ketamine has been researched along with Anorexia Nervosa in 11 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Anorexia Nervosa: An eating disorder that is characterized by the lack or loss of APPETITE, known as ANOREXIA. Other features include excess fear of becoming OVERWEIGHT; BODY IMAGE disturbance; significant WEIGHT LOSS; refusal to maintain minimal normal weight; and AMENORRHEA. This disorder occurs most frequently in adolescent females. (APA, Thesaurus of Psychological Index Terms, 1994)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In response to our narrative review, which suggested the use of the glutamatergic n-methyl-D-aspartate (NMDA) receptor antagonist ketamine as a potential treatment for anorexia nervosa (AN) [." | 9.22 | Reply to Skokou, M. Comment on "Keeler et al. Ketamine as a Treatment for Anorexia Nervosa: A Narrative Review. ( Himmerich, H; Juruena, MF; Kan, C; Keeler, JL; Treasure, J, 2022) |
| "Through serendipity, we observed an apparent synergy between adopting a ketogenic diet and receiving ketamine infusions that led to complete and durable remission in two patients with chronic enduring anorexia nervosa." | 8.31 | Synergy between ketamine and ketogenic diet in anorexia nervosa, and other neurobehavioral disorders. ( Beckwith, C; Scolnick, B, 2023) |
| "We describe an episode of apnea, a rare adverse event of ketamine, which was given for procedural sedation to a severely malnourished 13-year-old female with anorexia nervosa, generalized anxiety disorder, and high-functioning autism spectrum disorder." | 8.12 | Apnea with ketamine sedation in a patient with severe anorexia nervosa: A case report. ( Joshi, R; Marvin, W, 2022) |
| "Anorexia nervosa is a disorder associated with serious adverse health outcomes, for which there is currently considerable treatment ineffectiveness." | 7.01 | Ketamine and Zinc: Treatment of Anorexia Nervosa Via Dual NMDA Receptor Modulation. ( Bennett, MR; Can, AT; Hermens, DF; Lagopoulos, J; Mitchell, JS, 2023) |
| "Ketamine has rapid antidepressant effects, which are hypothesised to occur via increases in glutamate, with sequelae including increased neuroplasticity, neurogenesis and synaptogenesis." | 6.72 | Ketamine as a Treatment for Anorexia Nervosa: A Narrative Review. ( Himmerich, H; Juruena, MF; Kan, C; Keeler, JL; Treasure, J, 2021) |
| "We describe an episode of apnea, a rare adverse event of ketamine, which was given for procedural sedation to a severely malnourished 13-year-old female with anorexia nervosa, generalized anxiety disorder, and high-functioning autism spectrum disorder." | 4.12 | Apnea with ketamine sedation in a patient with severe anorexia nervosa: A case report. ( Joshi, R; Marvin, W, 2022) |
| "Ketamine has rapid antidepressant effects, which are hypothesised to occur via increases in glutamate, with sequelae including increased neuroplasticity, neurogenesis and synaptogenesis." | 2.72 | Ketamine as a Treatment for Anorexia Nervosa: A Narrative Review. ( Himmerich, H; Juruena, MF; Kan, C; Keeler, JL; Treasure, J, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 10 (90.91) | 2.80 |
| Authors | Studies |
|---|---|
| Keeler, JL | 2 |
| Treasure, J | 2 |
| Juruena, MF | 2 |
| Kan, C | 2 |
| Himmerich, H | 2 |
| Skokou, M | 1 |
| Calabrese, L | 1 |
| Scolnick, B | 2 |
| Zupec-Kania, B | 1 |
| Beckwith, C | 2 |
| Costello, K | 1 |
| Frank, GKW | 1 |
| Temizer, R | 1 |
| Chen, YW | 1 |
| Aoki, C | 1 |
| Mitchell, JS | 1 |
| Hermens, DF | 3 |
| Bennett, MR | 1 |
| Can, AT | 2 |
| Lagopoulos, J | 3 |
| Elwyn, R | 1 |
| Mitchell, J | 1 |
| Kohn, MR | 1 |
| Driver, C | 1 |
| Hay, P | 1 |
| Simcock, G | 1 |
| Dutton, M | 1 |
| Bouças, AP | 1 |
| Lilley, C | 1 |
| Joshi, R | 1 |
| Marvin, W | 1 |
| Wink, LK | 1 |
| O'Melia, AM | 1 |
| Shaffer, RC | 1 |
| Pedapati, E | 1 |
| Friedmann, K | 1 |
| Schaefer, T | 1 |
| Erickson, CA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ketogenic Diet in Weight Recovered Anorexia Nervosa to Target Metabolism and Normalize Persistent Eating Disorder Psychopathology[NCT06000774] | 20 participants (Anticipated) | Interventional | 2023-10-03 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for ketamine and Anorexia Nervosa
| Article | Year |
|---|---|
Ketamine as a Treatment for Anorexia Nervosa: A Narrative Review.
Topics: Anorexia Nervosa; Antidepressive Agents; Brain; Comorbidity; Depression; Glutamic Acid; Humans; Keta | 2021 |
Comment on Keeler et al. Ketamine as a Treatment for Anorexia Nervosa: A Narrative Review.
Topics: Adolescent; Anorexia Nervosa; Female; Humans; Incidence; Ketamine; Nutrients; Prevalence | 2022 |
Reply to Skokou, M. Comment on "Keeler et al. Ketamine as a Treatment for Anorexia Nervosa: A Narrative Review.
Topics: Anorexia Nervosa; Humans; Ketamine; Nutrients | 2022 |
Ketamine and Zinc: Treatment of Anorexia Nervosa Via Dual NMDA Receptor Modulation.
Topics: Anorexia Nervosa; Brain; Humans; Ketamine; Receptors, N-Methyl-D-Aspartate; Zinc | 2023 |
Novel ketamine and zinc treatment for anorexia nervosa and the potential beneficial interactions with the gut microbiome.
Topics: Anorexia Nervosa; Brain; Gastrointestinal Microbiome; Humans; Ketamine; Zinc | 2023 |
Anorexia nervosa, zinc deficiency and the glutamate system: The ketamine option.
Topics: Animals; Anorexia Nervosa; Dietary Supplements; Excitatory Amino Acid Antagonists; Glutamic Acid; Hu | 2020 |
1 trial available for ketamine and Anorexia Nervosa
| Article | Year |
|---|---|
Ketogenic diet and ketamine infusion treatment to target chronic persistent eating disorder psychopathology in anorexia nervosa: a pilot study.
Topics: Adult; Anorexia Nervosa; Diet, Ketogenic; Feeding and Eating Disorders; Humans; Ketamine; Pilot Proj | 2022 |
4 other studies available for ketamine and Anorexia Nervosa
| Article | Year |
|---|---|
Individual differences in the positive outcome from adolescent ketamine treatment in a female mouse model of anorexia nervosa involve drebrin A at excitatory synapses of the medial prefrontal cortex.
Topics: Animals; Anorexia; Anorexia Nervosa; Cytoplasm; Disease Models, Animal; Female; gamma-Aminobutyric A | 2023 |
Synergy between ketamine and ketogenic diet in anorexia nervosa, and other neurobehavioral disorders.
Topics: Anorexia Nervosa; Diet, Ketogenic; Humans; Ketamine | 2023 |
Apnea with ketamine sedation in a patient with severe anorexia nervosa: A case report.
Topics: Adolescent; Anesthesia; Anesthetics, Dissociative; Anorexia Nervosa; Apnea; Autism Spectrum Disorder | 2022 |
Intranasal ketamine treatment in an adult with autism spectrum disorder.
Topics: Administration, Intranasal; Adult; Anorexia Nervosa; Child Development Disorders, Pervasive; Depress | 2014 |