Page last updated: 2024-10-29

ketamine and Amyotrophic Lateral Sclerosis

ketamine has been researched along with Amyotrophic Lateral Sclerosis in 3 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Gold, ND1
Mallard, AJ1
Hermann, JC1
Zeifman, RJ1
Pagni, BA1
Bogenschutz, MP1
Ross, S1
Zilio, F1
Gomez-Pilar, J1
Cao, S1
Zhang, J1
Zang, D1
Qi, Z1
Tan, J1
Hiromi, T1
Wu, X1
Fogel, S1
Huang, Z1
Hohmann, MR1
Fomina, T1
Synofzik, M1
Grosse-Wentrup, M1
Owen, AM1
Northoff, G1
Marcos Vidal, JM1
Bermejo González, JC1
Baticón Escudero, PM1

Reviews

1 review available for ketamine and Amyotrophic Lateral Sclerosis

ArticleYear
Exploring the Potential Utility of Psychedelic Therapy for Patients With Amyotrophic Lateral Sclerosis.
    Journal of palliative medicine, 2023, Volume: 26, Issue:10

    Topics: Amyotrophic Lateral Sclerosis; Hallucinogens; Humans; Ketamine; Motor Neuron Disease; Neurodegenerat

2023

Other Studies

2 other studies available for ketamine and Amyotrophic Lateral Sclerosis

ArticleYear
Are intrinsic neural timescales related to sensory processing? Evidence from abnormal behavioral states.
    NeuroImage, 2021, 02-01, Volume: 226

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Anesthesia, General; Anesthetics, General; Brain; Case-C

2021
[Noninvasive ventilation through a nasal mask to sedate a man with amyotrophic lateral sclerosis during percutaneous endoscopic gastrostomy].
    Revista espanola de anestesiologia y reanimacion, 2011, Volume: 58, Issue:4

    Topics: Amyotrophic Lateral Sclerosis; Apnea; Deep Sedation; Endoscopy; Enteral Nutrition; Gastrostomy; Huma

2011