Page last updated: 2024-10-29

ketamine and Alcoholic Intoxication

ketamine has been researched along with Alcoholic Intoxication in 8 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Alcoholic Intoxication: An acute brain syndrome which results from the excessive ingestion of ETHANOL or ALCOHOLIC BEVERAGES.

Research Excerpts

ExcerptRelevanceReference
"Ketamine effects also were more like ethanol than marijuana or cocaine."2.69Dose-related ethanol-like effects of the NMDA antagonist, ketamine, in recently detoxified alcoholics. ( Charney, DS; Cooney, NL; Karper, LP; Krystal, JH; Namanworth, S; Petrakis, IL; Stetson, P; Trevisan, LA; Webb, E, 1998)
"This review addressed the adverse effects of the frequently-used recreational drug, ketamine through using mice and monkey models."2.49Long term ketamine and ketamine plus alcohol toxicity - what can we learn from animal models? ( Chan, WM; Fan, M; Jiang, Y; Lam, WP; Luan, P; Tang, HC; Tsui, TY; Wai, MS; Yew, DT, 2013)
"Ketamine was administered for agitation on 32 visits involving 27 patients."1.42Ketamine use for acute agitation in the emergency department. ( Campillo, A; Castillo, EM; Davie, T; Hopper, AB; Vilke, GM; Wilson, MP, 2015)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hopper, AB1
Vilke, GM1
Castillo, EM1
Campillo, A1
Davie, T1
Wilson, MP1
Dickerson, D1
Pittman, B1
Ralevski, E1
Perrino, A1
Limoncelli, D2
Edgecombe, J1
Acampora, G1
Krystal, JH4
Petrakis, I1
Wai, MS1
Luan, P1
Jiang, Y1
Chan, WM1
Tsui, TY1
Tang, HC1
Lam, WP1
Fan, M1
Yew, DT1
Petrakis, IL3
Krupitsky, E1
Schutz, C1
Trevisan, L2
D'Souza, DC1
Gueorguieva, R1
Jatlow, P1
Boutros, NN1
Gelernter, J1
Westerman, ST1
Gilbert, LM1
Webb, E1
Cooney, NL1
Karper, LP1
Namanworth, S1
Stetson, P1
Trevisan, LA1
Charney, DS1
Kronz, CS1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
ED Treatment of Suicidal Patients With Ketamine Infusion[NCT03502551]Phase 20 participants (Actual)Interventional2019-04-01Withdrawn (stopped due to Trial never received funding.)
Study of the Efficacity of the Systemic Ketamine for the Improvement of Post-Operative Analgesia After ORL Carcinological Surgery at the Alcohol-Dependent Patient.[NCT00329394]Phase 356 participants (Anticipated)Interventional2006-04-30Suspended
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for ketamine and Alcoholic Intoxication

ArticleYear
Long term ketamine and ketamine plus alcohol toxicity - what can we learn from animal models?
    Mini reviews in medicinal chemistry, 2013, Volume: 13, Issue:2

    Topics: Alcoholic Intoxication; Anesthetics, Dissociative; Animals; Brain; Haplorhini; Ketamine; Kidney; Liv

2013
NMDA receptor antagonism and the ethanol intoxication signal: from alcoholism risk to pharmacotherapy.
    Annals of the New York Academy of Sciences, 2003, Volume: 1003

    Topics: Alcoholic Intoxication; Alcoholism; Animals; Ethanol; Excitatory Amino Acid Antagonists; Humans; Ket

2003

Trials

3 trials available for ketamine and Alcoholic Intoxication

ArticleYear
Ethanol-like effects of thiopental and ketamine in healthy humans.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:2

    Topics: Adult; Alcohol Drinking; Alcoholic Intoxication; Double-Blind Method; Ethanol; Excitatory Amino Acid

2010
Altered NMDA glutamate receptor antagonist response in individuals with a family vulnerability to alcoholism.
    The American journal of psychiatry, 2004, Volume: 161, Issue:10

    Topics: Adult; Affect; Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Brief Psychiatric Rating Scale;

2004
Dose-related ethanol-like effects of the NMDA antagonist, ketamine, in recently detoxified alcoholics.
    Archives of general psychiatry, 1998, Volume: 55, Issue:4

    Topics: Adolescent; Adult; Age of Onset; Alcoholic Intoxication; Alcoholism; Dose-Response Relationship, Dru

1998

Other Studies

3 other studies available for ketamine and Alcoholic Intoxication

ArticleYear
Ketamine use for acute agitation in the emergency department.
    The Journal of emergency medicine, 2015, Volume: 48, Issue:6

    Topics: Adult; Aged; Aggression; Alcoholic Intoxication; Anesthetics, Dissociative; Antipsychotic Agents; Be

2015
A non-invasive method of qualitative and quantitative measurement of drugs.
    The Laryngoscope, 1981, Volume: 91, Issue:9 Pt 1

    Topics: Alcoholic Intoxication; Cocaine; Diazepam; Electronystagmography; Ethanol; Humans; Illicit Drugs; Ke

1981
A 30-year-old woman with possible unknown ingestion of date rape drugs.
    Journal of emergency nursing, 2000, Volume: 26, Issue:6

    Topics: Adult; Alcoholic Intoxication; Anti-Anxiety Agents; Datura stramonium; Diagnosis, Differential; Fema

2000