ketamine has been researched along with Addiction, Opioid in 26 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Excerpt | Relevance | Reference |
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"Managing severe acute nociceptive pain in buprenorphine-maintained individuals for opioid use disorder management is challenging owing to the high affinity and very slow dissociation of buprenorphine from μ-opioid receptors that hinders the use of full agonist opioid analgesics." | 7.96 | Efficacy of multimodal analgesic treatment of severe traumatic acute pain in mice pretreated with chronic high dose of buprenorphine inducing mechanical allodynia. ( Bounes, V; Coutens, B; Derreumaux, C; Frances, B; Guiard, BP; Labaste, F; Minville, V; Moulédous, L; Roussin, A, 2020) |
"Ketamine is an N-methyl-d-aspartate receptor antagonist that has been shown to be useful in the reduction of acute postoperative pain and analgesic consumption in a variety of surgical interventions with variable routes of administration." | 6.75 | Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery. ( Abdu, WA; Beach, ML; Brown, JR; Clark, JA; Loftus, RW; Sengupta, DK; Yeager, MP, 2010) |
" The acute pain group did not show an opioid reduction associated with the ketamine infusions." | 4.12 | Low-dose ketamine infusions reduce opioid use in pediatric and young adult oncology patients. ( Anghelescu, DL; Li, Y; Morgan, KJ; Patni, T; Ryan, S; Wu, D, 2022) |
"Managing severe acute nociceptive pain in buprenorphine-maintained individuals for opioid use disorder management is challenging owing to the high affinity and very slow dissociation of buprenorphine from μ-opioid receptors that hinders the use of full agonist opioid analgesics." | 3.96 | Efficacy of multimodal analgesic treatment of severe traumatic acute pain in mice pretreated with chronic high dose of buprenorphine inducing mechanical allodynia. ( Bounes, V; Coutens, B; Derreumaux, C; Frances, B; Guiard, BP; Labaste, F; Minville, V; Moulédous, L; Roussin, A, 2020) |
"We describe an opioid-tolerant patient with severe acute pain which was unrelieved by morphine and ketamine via intravenous patient-controlled analgesia, but almost totally relieved by methadone." | 3.71 | Successful use of oral methadone after failure of intravenous morphine and ketamine. ( Mitchell, SJ; Sartain, JB, 2002) |
"Ketamine has been used as part of a multimodal analgesia regime in opioid abusers undergoing general anesthesia." | 2.78 | Opioid-sparing effect of preemptive bolus low-dose ketamine for moderate sedation in opioid abusers undergoing extracorporeal shock wave lithotripsy: a randomized clinical trial. ( Aghamohammadi, H; Elyassi, H; Gharaei, B; Jafari, A; Kamranmanesh, M; Poorzamani, M; Rostamian, B; Salimi, A, 2013) |
"Ketamine is an N-methyl-d-aspartate receptor antagonist that has been shown to be useful in the reduction of acute postoperative pain and analgesic consumption in a variety of surgical interventions with variable routes of administration." | 2.75 | Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery. ( Abdu, WA; Beach, ML; Brown, JR; Clark, JA; Loftus, RW; Sengupta, DK; Yeager, MP, 2010) |
"Demand for treatments for severe opioid use disorder is increasing worldwide." | 2.66 | Clinical benefits and risks of N-methyl-d-aspartate receptor antagonists to treat severe opioid use disorder: A systematic review. ( Fluyau, D; Pierre, CG; Revadigar, N, 2020) |
"The number of registered drug abusers increased from 70,000 in 1990 to more than one million by the end of 2004." | 2.43 | Recent trends in drug abuse in China. ( Fang, YX; Liu, ZM; Lu, L; Shi, J; Wang, YB, 2006) |
" Inadequate doses or dosing regimens should be avoided." | 2.39 | Pharmacology of intravenous sedatives and opioids in critically ill patients. ( Levine, RL, 1994) |
"The growing social problem of drug abuse has increased the likelihood that anesthesiologists will find acute or chronic drug users among patients requiring anesthesia for elective or emergency surgery." | 1.37 | [Anesthesia in drug addiction]. ( Uña Orejón, R; Vázquez Moyano, M, 2011) |
"S(+)-ketamine is a valuable adjunct in the anesthetic regimen, since it attenuates hyperactivity of the central nervous system during rapid opioid detoxification." | 1.33 | S(+)-ketamine attenuates increase in electroencephalograph activity and amplitude height of sensory-evoked potentials during rapid opioid detoxification. ( Freye, E; Latasch, L; Levy, JV, 2006) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (11.54) | 18.2507 |
2000's | 4 (15.38) | 29.6817 |
2010's | 11 (42.31) | 24.3611 |
2020's | 8 (30.77) | 2.80 |
Authors | Studies |
---|---|
Silverstein, WK | 1 |
Juurlink, DN | 1 |
Zipursky, JS | 1 |
Anghelescu, DL | 1 |
Ryan, S | 1 |
Wu, D | 1 |
Morgan, KJ | 1 |
Patni, T | 1 |
Li, Y | 1 |
Ocker, AC | 1 |
Shah, NB | 1 |
Schwenk, ES | 1 |
Witkowski, TA | 1 |
Cohen, MJ | 1 |
Viscusi, ER | 1 |
Lin, C | 1 |
Wong, BY | 1 |
Lo, MT | 1 |
Chiu, YC | 1 |
Lin, YH | 1 |
Coutens, B | 1 |
Derreumaux, C | 1 |
Labaste, F | 1 |
Minville, V | 1 |
Guiard, BP | 1 |
Moulédous, L | 1 |
Bounes, V | 1 |
Roussin, A | 1 |
Frances, B | 1 |
Fluyau, D | 1 |
Revadigar, N | 1 |
Pierre, CG | 1 |
Witkin, JM | 1 |
Kranzler, J | 1 |
Kaniecki, K | 1 |
Popik, P | 1 |
Smith, JL | 1 |
Hashimoto, K | 1 |
Sporn, J | 1 |
Cobb, J | 1 |
Craig, W | 1 |
Richard, J | 1 |
Snow, E | 1 |
Turcotte, H | 1 |
Warters, R | 1 |
Quaye, A | 1 |
Zeballos, JL | 1 |
Lirk, P | 1 |
Rathmell, JP | 1 |
Nielsen, RV | 2 |
Fomsgaard, JS | 2 |
Nikolajsen, L | 2 |
Dahl, JB | 2 |
Mathiesen, O | 2 |
Barelli, R | 1 |
Morelli Sbarra, G | 1 |
Sbaraglia, F | 1 |
Zappia, L | 1 |
Rossi, M | 1 |
Kim, BW | 1 |
Peskin, RM | 1 |
Siegel, H | 1 |
Martusevicius, R | 1 |
Fredheim, OM | 1 |
Nøstdahl, T | 1 |
Nordstrand, B | 1 |
Høivik, T | 1 |
Rygnestad, T | 1 |
Borchgrevink, PC | 1 |
Angst, MS | 1 |
Clark, JD | 1 |
Loftus, RW | 1 |
Yeager, MP | 1 |
Clark, JA | 1 |
Brown, JR | 1 |
Abdu, WA | 1 |
Sengupta, DK | 1 |
Beach, ML | 1 |
Vázquez Moyano, M | 1 |
Uña Orejón, R | 1 |
Seigne, RD | 1 |
Gharaei, B | 1 |
Jafari, A | 1 |
Aghamohammadi, H | 1 |
Kamranmanesh, M | 1 |
Poorzamani, M | 1 |
Elyassi, H | 1 |
Rostamian, B | 1 |
Salimi, A | 1 |
Sartain, JB | 1 |
Mitchell, SJ | 1 |
Fang, YX | 1 |
Wang, YB | 1 |
Shi, J | 1 |
Liu, ZM | 1 |
Lu, L | 1 |
Freye, E | 1 |
Latasch, L | 1 |
Levy, JV | 1 |
Levine, RL | 1 |
Nicolodi, M | 1 |
Del Bianco, PL | 1 |
Sicuteri, F | 1 |
Connor, DF | 1 |
Muir, A | 1 |
Haller, G | 1 |
Waeber, JL | 1 |
Infante, NK | 1 |
Clergue, F | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Efficacy of Different Dose Esketamine and Dexmedetomidine Combination for Supplemental Analgesia After Scoliosis Correction Surgery: A Randomized, Double-blind Trial[NCT06062550] | Phase 4 | 312 participants (Anticipated) | Interventional | 2023-10-31 | Not yet recruiting | ||
Impact of Different Dose Esketamine and Dexmedetomidine Combination for Supplemental Analgesia on Long-term Outcomes After Scoliosis Correction Surgery: Follow-up of a Randomized Trial[NCT06087510] | Phase 4 | 312 participants (Anticipated) | Interventional | 2024-01-31 | Not yet recruiting | ||
Analgesic Effects of Low-dose S-ketamine in Patients Undergoing Major Spine Fusion Surgery: A Double-blinded, Randomized Controlled Trial[NCT04964219] | Phase 4 | 164 participants (Anticipated) | Interventional | 2022-02-08 | Recruiting | ||
Effect of Mini-dose Esketamine-dexmedetomidine Supplemented Analgesia on Long-term Outcomes Following Scoliosis Correction Surgery: 2-year Follow-up of a Randomized Controlled Trial[NCT05718544] | Phase 4 | 199 participants (Actual) | Interventional | 2023-01-30 | Active, not recruiting | ||
Prospective Randomized Double Blind Study of Intraoperative Dexmedetomidine and Postoperative Pain Control in Patients Undergoing Multi-level Thoraco-lumbar Spine Surgery[NCT01850017] | Phase 4 | 142 participants (Actual) | Interventional | 2012-08-31 | Completed | ||
The Effect of Intraoperative Ketamine on Opioid Consumption and Pain After Spine Surgery in Opioid-dependent Patients[NCT02085577] | Phase 4 | 147 participants (Actual) | Interventional | 2014-05-31 | Completed | ||
A Prospective, Block Randomized, Double-Blind Placebo-Controlled Trial of Ketamine in Patients Undergoing Anterior Cervical Discectomy and Fusion[NCT02378740] | Phase 4 | 0 participants (Actual) | Interventional | 2015-04-30 | Withdrawn (stopped due to PI has left the University) | ||
A Prospective, Randomized, Single Blinded Comparison of Intraoperative Ketamine Infusion Versus Placebo in Patients Having Spinal Fusion[NCT02424591] | Phase 4 | 46 participants (Actual) | Interventional | 2014-08-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
"Beck's Depression Inventory (BDI) is a 21-item, self-report rating inventory that measures attitudes and symptoms of depression. Each sentence has a rating from 0 to 3 and the sentences go from mild to fairly severe descriptions of moods. The numbers are tabulated, the lowest possible score is 0 and the highest is 63.~A score of 1-10 indicates normal ups and downs. 11-16 indicates a mild mood disturbance; 17-20, borderline clinical depression; 21-30, moderate depression; 31-40, severe depression; over 40, extreme depression" (NCT02424591)
Timeframe: Post-op Day 3
Intervention | points (Median) |
---|---|
Ketamine | 8 |
Placebo | 9 |
"McGill Short Form measures pain in different ways. The first part of the form lists 15 adjectives for pain, for which the answers can be none (0), Mild (1), Moderate (2) and Severe (3). Descriptors 1-11 represent the sensory dimension of pain experience and 12-15 represent the affective dimension. A score of 0 is good, and a score of 45 indicates extreme pain. The lower the score the less pain a subject feels (better), as the scores go up, so do the pain levels (worse).~PPI (Present Pain Intensity) asks patients to measure pain from 0 (no pain) to 5 (excruciating). Again, a lower score is ideal." (NCT02424591)
Timeframe: Post-op Day 3
Intervention | points (Median) |
---|---|
Ketamine | 11 |
Placebo | 10.5 |
Quality of Recovery 15 questions questionnaires that ask, on a scale of 0-10, with 0 always being bad and 10 always being best, how the patient is recovering. The total number is reviewed, so the highest total score possible is 150 and the lowest is 0. (NCT02424591)
Timeframe: Post-op Day 3
Intervention | points (Median) |
---|---|
Ketamine | 95 |
Placebo | 101 |
4 reviews available for ketamine and Addiction, Opioid
Article | Year |
---|---|
Clinical benefits and risks of N-methyl-d-aspartate receptor antagonists to treat severe opioid use disorder: A systematic review.
Topics: Analgesics, Opioid; Excitatory Amino Acid Antagonists; Humans; Ketamine; Memantine; Methadone; Opiat | 2020 |
[Treatment of acute pain during drug-assisted rehabilitation].
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents | 2010 |
Recent trends in drug abuse in China.
Topics: China; Drug and Narcotic Control; HIV Infections; Ketamine; N-Methyl-3,4-methylenedioxyamphetamine; | 2006 |
Pharmacology of intravenous sedatives and opioids in critically ill patients.
Topics: Analgesics, Opioid; Antipsychotic Agents; Barbiturates; Benzodiazepines; Cardiovascular System; Crit | 1994 |
4 trials available for ketamine and Addiction, Opioid
Article | Year |
---|---|
Intraoperative S-ketamine for the reduction of opioid consumption and pain one year after spine surgery: A randomized clinical trial of opioid-dependent patients.
Topics: Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Female; Hu | 2019 |
Intraoperative S-ketamine for the reduction of opioid consumption and pain one year after spine surgery: A randomized clinical trial of opioid-dependent patients.
Topics: Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Female; Hu | 2019 |
Intraoperative S-ketamine for the reduction of opioid consumption and pain one year after spine surgery: A randomized clinical trial of opioid-dependent patients.
Topics: Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Female; Hu | 2019 |
Intraoperative S-ketamine for the reduction of opioid consumption and pain one year after spine surgery: A randomized clinical trial of opioid-dependent patients.
Topics: Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Female; Hu | 2019 |
Intraoperative S-ketamine for the reduction of opioid consumption and pain one year after spine surgery: A randomized clinical trial of opioid-dependent patients.
Topics: Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Female; Hu | 2019 |
Intraoperative S-ketamine for the reduction of opioid consumption and pain one year after spine surgery: A randomized clinical trial of opioid-dependent patients.
Topics: Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Female; Hu | 2019 |
Intraoperative S-ketamine for the reduction of opioid consumption and pain one year after spine surgery: A randomized clinical trial of opioid-dependent patients.
Topics: Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Female; Hu | 2019 |
Intraoperative S-ketamine for the reduction of opioid consumption and pain one year after spine surgery: A randomized clinical trial of opioid-dependent patients.
Topics: Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Female; Hu | 2019 |
Intraoperative S-ketamine for the reduction of opioid consumption and pain one year after spine surgery: A randomized clinical trial of opioid-dependent patients.
Topics: Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Female; Hu | 2019 |
Intraoperative S-ketamine for the reduction of opioid consumption and pain one year after spine surgery: A randomized clinical trial of opioid-dependent patients.
Topics: Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Female; Hu | 2019 |
Intraoperative S-ketamine for the reduction of opioid consumption and pain one year after spine surgery: A randomized clinical trial of opioid-dependent patients.
Topics: Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Female; Hu | 2019 |
Intraoperative S-ketamine for the reduction of opioid consumption and pain one year after spine surgery: A randomized clinical trial of opioid-dependent patients.
Topics: Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Female; Hu | 2019 |
Intraoperative S-ketamine for the reduction of opioid consumption and pain one year after spine surgery: A randomized clinical trial of opioid-dependent patients.
Topics: Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Female; Hu | 2019 |
Intraoperative S-ketamine for the reduction of opioid consumption and pain one year after spine surgery: A randomized clinical trial of opioid-dependent patients.
Topics: Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Female; Hu | 2019 |
Intraoperative S-ketamine for the reduction of opioid consumption and pain one year after spine surgery: A randomized clinical trial of opioid-dependent patients.
Topics: Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Female; Hu | 2019 |
Intraoperative S-ketamine for the reduction of opioid consumption and pain one year after spine surgery: A randomized clinical trial of opioid-dependent patients.
Topics: Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Female; Hu | 2019 |
Intraoperative ketamine reduces immediate postoperative opioid consumption after spinal fusion surgery in chronic pain patients with opioid dependency: a randomized, blinded trial.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Chronic Pain; Double-Bli | 2017 |
Intraoperative ketamine reduces immediate postoperative opioid consumption after spinal fusion surgery in chronic pain patients with opioid dependency: a randomized, blinded trial.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Chronic Pain; Double-Bli | 2017 |
Intraoperative ketamine reduces immediate postoperative opioid consumption after spinal fusion surgery in chronic pain patients with opioid dependency: a randomized, blinded trial.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Chronic Pain; Double-Bli | 2017 |
Intraoperative ketamine reduces immediate postoperative opioid consumption after spinal fusion surgery in chronic pain patients with opioid dependency: a randomized, blinded trial.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Chronic Pain; Double-Bli | 2017 |
Intraoperative ketamine reduces immediate postoperative opioid consumption after spinal fusion surgery in chronic pain patients with opioid dependency: a randomized, blinded trial.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Chronic Pain; Double-Bli | 2017 |
Intraoperative ketamine reduces immediate postoperative opioid consumption after spinal fusion surgery in chronic pain patients with opioid dependency: a randomized, blinded trial.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Chronic Pain; Double-Bli | 2017 |
Intraoperative ketamine reduces immediate postoperative opioid consumption after spinal fusion surgery in chronic pain patients with opioid dependency: a randomized, blinded trial.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Chronic Pain; Double-Bli | 2017 |
Intraoperative ketamine reduces immediate postoperative opioid consumption after spinal fusion surgery in chronic pain patients with opioid dependency: a randomized, blinded trial.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Chronic Pain; Double-Bli | 2017 |
Intraoperative ketamine reduces immediate postoperative opioid consumption after spinal fusion surgery in chronic pain patients with opioid dependency: a randomized, blinded trial.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Chronic Pain; Double-Bli | 2017 |
Intraoperative ketamine reduces immediate postoperative opioid consumption after spinal fusion surgery in chronic pain patients with opioid dependency: a randomized, blinded trial.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Chronic Pain; Double-Bli | 2017 |
Intraoperative ketamine reduces immediate postoperative opioid consumption after spinal fusion surgery in chronic pain patients with opioid dependency: a randomized, blinded trial.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Chronic Pain; Double-Bli | 2017 |
Intraoperative ketamine reduces immediate postoperative opioid consumption after spinal fusion surgery in chronic pain patients with opioid dependency: a randomized, blinded trial.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Chronic Pain; Double-Bli | 2017 |
Intraoperative ketamine reduces immediate postoperative opioid consumption after spinal fusion surgery in chronic pain patients with opioid dependency: a randomized, blinded trial.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Chronic Pain; Double-Bli | 2017 |
Intraoperative ketamine reduces immediate postoperative opioid consumption after spinal fusion surgery in chronic pain patients with opioid dependency: a randomized, blinded trial.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Chronic Pain; Double-Bli | 2017 |
Intraoperative ketamine reduces immediate postoperative opioid consumption after spinal fusion surgery in chronic pain patients with opioid dependency: a randomized, blinded trial.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Chronic Pain; Double-Bli | 2017 |
Intraoperative ketamine reduces immediate postoperative opioid consumption after spinal fusion surgery in chronic pain patients with opioid dependency: a randomized, blinded trial.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Chronic Pain; Double-Bli | 2017 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery.
Topics: Adult; Aged; Analgesics, Opioid; Back Pain; Chronic Disease; Double-Blind Method; Elective Surgical | 2010 |
Opioid-sparing effect of preemptive bolus low-dose ketamine for moderate sedation in opioid abusers undergoing extracorporeal shock wave lithotripsy: a randomized clinical trial.
Topics: Adolescent; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissociative; Con | 2013 |
18 other studies available for ketamine and Addiction, Opioid
Article | Year |
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Ketamine for the treatment of acute pain.
Topics: Acute Pain; Analgesics; Analgesics, Opioid; Contraindications, Drug; Dose-Response Relationship, Dru | 2021 |
Low-dose ketamine infusions reduce opioid use in pediatric and young adult oncology patients.
Topics: Acute Pain; Analgesics; Analgesics, Opioid; Child; Death; Humans; Infusions, Intravenous; Ketamine; | 2022 |
Ketamine and Cognitive Behavioral Therapy for Rapid Opioid Tapering With Sustained Opioid Abstinence: A Case Report and 1-Year Follow-up.
Topics: Analgesics; Analgesics, Opioid; Cognitive Behavioral Therapy; Follow-Up Studies; Humans; Hydromorpho | 2020 |
Development of an addiction index and delineation 15-year trends of illicit drugs from the Taiwan national drug enhancement database.
Topics: Amphetamine-Related Disorders; Anesthetics, Dissociative; Cannabis; Central Nervous System Stimulant | 2020 |
Efficacy of multimodal analgesic treatment of severe traumatic acute pain in mice pretreated with chronic high dose of buprenorphine inducing mechanical allodynia.
Topics: Acute Pain; Analgesics; Animals; Buprenorphine; Dose-Response Relationship, Drug; Drug Therapy, Comb | 2020 |
R-(-)-ketamine modifies behavioral effects of morphine predicting efficacy as a novel therapy for opioid use disorder
Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Dose-Response Relationship, Drug; Humans; Ketami | 2020 |
Low-dose ketamine infusion for post-cesarean delivery analgesia in patients with opioid use disorder.
Topics: Analgesia; Analgesics, Opioid; Cesarean Section; Double-Blind Method; Female; Humans; Ketamine; Opio | 2021 |
Low-Dose Ketamine for Acute Pain Management: A Timely Nudge Toward Multimodal Analgesia.
Topics: Acute Pain; Analgesia; Analgesics; Dose-Response Relationship, Drug; Humans; Ketamine; Opioid-Relate | 2018 |
Prevention of post-operative hyperalgesia in a heroin-addicted patient on methadone maintenance.
Topics: Analgesics, Opioid; Heroin; Humans; Hyperalgesia; Ketamine; Male; Methadone; Middle Aged; Opioid-Rel | 2019 |
Dexmedetomidine, ketamine, and midazolam for oral rehabilitation: a case report.
Topics: Adult; Analgesics, Opioid; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Dissociative; Ane | 2015 |
Ketamine for managing perioperative pain in opioid-dependent patients with chronic pain: a unique indication?
Topics: Chronic Disease; Disease Management; Humans; Ketamine; Opioid-Related Disorders; Pain; Pain, Postope | 2010 |
[Anesthesia in drug addiction].
Topics: Anesthesia; Cannabinoids; Cocaine-Related Disorders; Hallucinogens; Humans; Ketamine; Opioid-Related | 2011 |
Intraoperative ketamine and chronic opioid use: less pain, more morphine?
Topics: Analgesics; Analgesics, Opioid; Chronic Disease; Follow-Up Studies; Humans; Intraoperative Care; Ket | 2011 |
Successful use of oral methadone after failure of intravenous morphine and ketamine.
Topics: Acute Disease; Administration, Oral; Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, O | 2002 |
S(+)-ketamine attenuates increase in electroencephalograph activity and amplitude height of sensory-evoked potentials during rapid opioid detoxification.
Topics: Adult; Electroencephalography; Evoked Potentials, Somatosensory; Female; Humans; Ketamine; Male; Mid | 2006 |
Modulation of excitatory amino acids pathway: a possible therapeutic approach to chronic daily headache associated with analgesic drugs abuse.
Topics: Acetates; Adult; Amines; Chronic Disease; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagon | 1997 |
Balanced analgesia for the management of pain associated with multiple fractured ribs in an opioid addict.
Topics: Adult; Amides; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Loca | 1998 |
Ketamine combined with morphine for the management of pain in an opioid addict.
Topics: Adult; Anesthetics, Intravenous; Female; Humans; Ketamine; Opioid-Related Disorders; Pain Measuremen | 2002 |