ketamine has been researched along with Acute Renal Colic in 7 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "IN ketamine is as effective as IV morphine for pain control in renal colic patients." | 9.41 | Intranasal ketamine versus intravenous morphine for pain management in patients with renal colic: a double-blind, randomized, controlled trial. ( Moharamzadeh, P; Paknezhad, SP; Pouraghaei, M; Rajabpour, ZV; Soleimanpour, H, 2021) |
| "The present study was conducted to compare the analgesic effect of intravenous fentanyl with that of intranasal ketamine in renal colic patients." | 9.34 | Comparing intranasal ketamine with intravenous fentanyl in reducing pain in patients with renal colic: A double-blind randomized clinical trial. ( Maleki Verki, M; Motamed, H; Mozafari, J; Sabouhi, A; Tirandaz, F, 2020) |
| " This study was conducted to compare the analgesic efficacy of morphine plus ketamine (MK) versus morphine plus placebo (MP) in patients with acute renal colic." | 9.30 | Comparing the analgesic efficacy of morphine plus ketamine versus morphine plus placebo in patients with acute renal colic: A double-blinded randomized controlled trial. ( Bozorgi, F; Erfanian Irankar, S; Hosseini, SA; Hosseininejad, SM; Jahanian, F; Moosazadeh, M; Shahbakhti, N, 2019) |
| "The findings suggest that the use of ketamine can produce a more rapid relief effect, and decrease the use of opioids which create various complications, including nausea and vomiting in patients, especially patients with renal colic." | 9.30 | Comparison of the Analgesic Effect of Intravenous Ketamine versus Intravenous Morphine in Reducing Pain of Renal Colic Patients: Double-Blind Clinical Trial Study. ( Delirrooyfard, A; Esfahani, SRN; Forouzan, A; Masoumi, K; Motamed, H, 2019) |
| "Given that combinations of morphine with low doses of ketamine in patients with renal colic pain causes more pain and morphine consumption reduction then this combination is suggested as an alternative treatment that could be utilized in patients with renal colic." | 9.27 | Can low-dose of ketamine reduce the need for morphine in renal colic? A double-blind randomized clinical trial. ( Abbasi, S; Bidi, N; Farsi, D; Hafezimoghadam, P; Mahshidfar, B; Mofidi, M; Rezai, M, 2018) |
| "To compare the effectiveness of intranasal (IN) ketamine versus intravenous (IV) morphine in reducing pain in patients with renal colic." | 9.24 | Comparison of intranasal ketamine versus IV morphine in reducing pain in patients with renal colic. ( Farnia, MR; Jalali, A; Momeni, M; Saeedi, M; Seyedhosseini, J; Vahidi, E, 2017) |
| "IN ketamine is as effective as IV morphine for pain control in renal colic patients." | 5.41 | Intranasal ketamine versus intravenous morphine for pain management in patients with renal colic: a double-blind, randomized, controlled trial. ( Moharamzadeh, P; Paknezhad, SP; Pouraghaei, M; Rajabpour, ZV; Soleimanpour, H, 2021) |
| "The present study was conducted to compare the analgesic effect of intravenous fentanyl with that of intranasal ketamine in renal colic patients." | 5.34 | Comparing intranasal ketamine with intravenous fentanyl in reducing pain in patients with renal colic: A double-blind randomized clinical trial. ( Maleki Verki, M; Motamed, H; Mozafari, J; Sabouhi, A; Tirandaz, F, 2020) |
| " This study was conducted to compare the analgesic efficacy of morphine plus ketamine (MK) versus morphine plus placebo (MP) in patients with acute renal colic." | 5.30 | Comparing the analgesic efficacy of morphine plus ketamine versus morphine plus placebo in patients with acute renal colic: A double-blinded randomized controlled trial. ( Bozorgi, F; Erfanian Irankar, S; Hosseini, SA; Hosseininejad, SM; Jahanian, F; Moosazadeh, M; Shahbakhti, N, 2019) |
| "The findings suggest that the use of ketamine can produce a more rapid relief effect, and decrease the use of opioids which create various complications, including nausea and vomiting in patients, especially patients with renal colic." | 5.30 | Comparison of the Analgesic Effect of Intravenous Ketamine versus Intravenous Morphine in Reducing Pain of Renal Colic Patients: Double-Blind Clinical Trial Study. ( Delirrooyfard, A; Esfahani, SRN; Forouzan, A; Masoumi, K; Motamed, H, 2019) |
| "Given that combinations of morphine with low doses of ketamine in patients with renal colic pain causes more pain and morphine consumption reduction then this combination is suggested as an alternative treatment that could be utilized in patients with renal colic." | 5.27 | Can low-dose of ketamine reduce the need for morphine in renal colic? A double-blind randomized clinical trial. ( Abbasi, S; Bidi, N; Farsi, D; Hafezimoghadam, P; Mahshidfar, B; Mofidi, M; Rezai, M, 2018) |
| "To compare the effectiveness of intranasal (IN) ketamine versus intravenous (IV) morphine in reducing pain in patients with renal colic." | 5.24 | Comparison of intranasal ketamine versus IV morphine in reducing pain in patients with renal colic. ( Farnia, MR; Jalali, A; Momeni, M; Saeedi, M; Seyedhosseini, J; Vahidi, E, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Pouraghaei, M | 1 |
| Moharamzadeh, P | 1 |
| Paknezhad, SP | 1 |
| Rajabpour, ZV | 1 |
| Soleimanpour, H | 1 |
| Abbasi, S | 1 |
| Bidi, N | 1 |
| Mahshidfar, B | 1 |
| Hafezimoghadam, P | 1 |
| Rezai, M | 1 |
| Mofidi, M | 1 |
| Farsi, D | 1 |
| Hosseininejad, SM | 1 |
| Jahanian, F | 1 |
| Erfanian Irankar, S | 1 |
| Moosazadeh, M | 1 |
| Hosseini, SA | 1 |
| Shahbakhti, N | 1 |
| Bozorgi, F | 1 |
| Mozafari, J | 1 |
| Maleki Verki, M | 1 |
| Motamed, H | 2 |
| Sabouhi, A | 1 |
| Tirandaz, F | 1 |
| Forouzan, A | 1 |
| Masoumi, K | 1 |
| Esfahani, SRN | 1 |
| Delirrooyfard, A | 1 |
| Farnia, MR | 1 |
| Jalali, A | 1 |
| Vahidi, E | 1 |
| Momeni, M | 1 |
| Seyedhosseini, J | 1 |
| Saeedi, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Combination Study With Sub-Dissociative Ketamine and Fentanyl to Treat Moderate to Severe Pain in the Emergency Department[NCT03959852] | Phase 4 | 6 participants (Actual) | Interventional | 2019-11-18 | Terminated (stopped due to Residency completed.) | ||
| Comparison of Ketamine 0.1 mg/kg, 0.2 mg/kg, and 0.3 mg/kg Intravenous Doses for Acute Pain in the Emergency Department: A Prospective, Randomized, Double-blind, Active-controlled, Clinical Trial[NCT03896230] | Phase 4 | 11 participants (Actual) | Interventional | 2019-05-03 | Terminated (stopped due to Due to resource limitations the study was on hold and was then terminated.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Frequency of adverse events secondary to ketamine including fatigue, dizziness, nausea, headache, feeling of unreality, changes in hearing or vision, mood changes, generalized discomfort, and hallucinations, changes in vital signs.~Adverse events were reported at baseline and then at 15 min/30 min/60 min/90 min and 120 minutes post-infusion." (NCT03896230)
Timeframe: Within 2 hours post infusion completion
| Intervention | participants (Number) | ||||
|---|---|---|---|---|---|
| at 15 min post infusion | at 30 min post infusion | at 60 min post infusion | at 90 min post infusion | at 120 min post infusion | |
| Arm 1: 0.1 mg/kg Ketamine | 2 | 1 | 1 | 1 | 1 |
| Arm 1: 0.2 mg/kg Ketamine | 3 | 2 | 2 | 2 | 0 |
| Arm 1: 0.3 mg/kg Ketamine | 2 | 1 | 0 | 0 | 0 |
"Pain score using Numerical Rating Scale (NRS) post ketamine infusion. The Numerical Rating Scale (NRS) ranges from 0-to-10 with 0 being no pain and lower numbers representing less pain, so in this case lower numbers will represent better outcomes.~Pain scores were reported at baseline and then at 15 min/30 min/60 min/90 min and 120 minutes post-infusion." (NCT03896230)
Timeframe: Within 2 hours post infusion completion
| Intervention | score on a scale (Mean) | ||||
|---|---|---|---|---|---|
| Baseline pain score | Pain score at 15 min | Pain score at 30 min | Pain score at 60 min | Pain score at 90 min | |
| Arm 1: 0.3 mg/kg Ketamine | 7.5 | 2 | 6 | 5 | 2 |
| Arm 1: 0.2 mg/kg Ketamine | 8.5 | 6 | 5.75 | 7 | 7 |
"Pain score using Numerical Rating Scale (NRS) post ketamine infusion. The Numerical Rating Scale (NRS) ranges from 0-to-10 with 0 being no pain and lower numbers representing less pain, so in this case lower numbers will represent better outcomes.~Pain scores were reported at baseline and then at 15 min/30 min/60 min/90 min and 120 minutes post-infusion." (NCT03896230)
Timeframe: Within 2 hours post infusion completion
| Intervention | score on a scale (Mean) | |||||
|---|---|---|---|---|---|---|
| Baseline pain score | Pain score at 15 min | Pain score at 30 min | Pain score at 60 min | Pain score at 90 min | Pain score at 120 min | |
| Arm 1: 0.1 mg/kg Ketamine | 9.4 | 5.25 | 5.25 | 5.25 | 4.5 | 4 |
6 trials available for ketamine and Acute Renal Colic
| Article | Year |
|---|---|
Intranasal ketamine versus intravenous morphine for pain management in patients with renal colic: a double-blind, randomized, controlled trial.
Topics: Administration, Intranasal; Adult; Double-Blind Method; Humans; Injections, Intravenous; Ketamine; M | 2021 |
Can low-dose of ketamine reduce the need for morphine in renal colic? A double-blind randomized clinical trial.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Therapy, Combination; E | 2018 |
Can low-dose of ketamine reduce the need for morphine in renal colic? A double-blind randomized clinical trial.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Therapy, Combination; E | 2018 |
Can low-dose of ketamine reduce the need for morphine in renal colic? A double-blind randomized clinical trial.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Therapy, Combination; E | 2018 |
Can low-dose of ketamine reduce the need for morphine in renal colic? A double-blind randomized clinical trial.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Therapy, Combination; E | 2018 |
Comparing the analgesic efficacy of morphine plus ketamine versus morphine plus placebo in patients with acute renal colic: A double-blinded randomized controlled trial.
Topics: Acute Disease; Adult; Analgesics; Dizziness; Double-Blind Method; Drug Therapy, Combination; Emergen | 2019 |
Comparing intranasal ketamine with intravenous fentanyl in reducing pain in patients with renal colic: A double-blind randomized clinical trial.
Topics: Administration, Intranasal; Adult; Anesthetics, Dissociative; Anesthetics, Intravenous; Double-Blind | 2020 |
Comparison of the Analgesic Effect of Intravenous Ketamine versus Intravenous Morphine in Reducing Pain of Renal Colic Patients: Double-Blind Clinical Trial Study.
Topics: Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Dose-Response Relationship, Drug; D | 2019 |
Comparison of intranasal ketamine versus IV morphine in reducing pain in patients with renal colic.
Topics: Abdominal Pain; Administration, Intranasal; Administration, Intravenous; Adult; Analgesics, Opioid; | 2017 |
1 other study available for ketamine and Acute Renal Colic
| Article | Year |
|---|---|
Topics: Analgesics; Humans; Ketamine; Morphine; Renal Colic | 2022 |