Page last updated: 2024-10-29

ketamine and Acute Pain

ketamine has been researched along with Acute Pain in 96 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Acute Pain: Intensely discomforting, distressful, or agonizing sensation associated with trauma or disease, with well-defined location, character, and timing.

Research Excerpts

ExcerptRelevanceReference
" Due to the reduction of this symptom with Haloperidol, we decided to design a randomized clinical trial to compare the analgesic effect of Ketamine with Haloperidol and Fentanyl in reducing acute pain and its complications."9.51Sub dissociative dose of ketamine with haloperidol versus fentanyl on pain reduction in patients with acute pain in the emergency department; a randomized clinical trial. ( Baratloo, A; Moradi, MM; Payandemehr, P; Safaie, A, 2022)
"ketamine has potential advantages over morphine for musculoskeletal pain relief."9.51Non-inferiority of intranasal ketamine compared to intravenous morphine for musculoskeletal pain relief among older adults in an emergency department: a randomised controlled trial. ( Paksophis, T; Sri-On, J; Thong-On, K; Tongbua, S, 2022)
" S(+)-ketamine is an N-methyl-D-aspartic acid (NMDA) receptor antagonist with a strong analgesic effect and can significantly relieve postoperative acute pain and reduce opioid consumption."9.51Evaluation of the effect of perioperative administration of S(+)-ketamine hydrochloride injection for postoperative acute pain in children: study protocol for a prospective, multicenter, randomized, open-label, parallel-group, pragmatic clinical trial. ( Chen, P; Duan, C; Lan, C; Mi, W; Qu, S; Sun, Y; Wang, H; Yang, L; Zhang, J; Zhou, L, 2022)
"The purpose of this study is to investigate if an orally administered combination of aspirin and ketamine will provide better analgesia than a ketamine alone in adult patients presenting to the Emergency Department (ED) with acute musculoskeletal pain."9.51Oral Aspirin/ketamine versus oral ketamine for emergency department patients with acute musculoskeletal pain. ( Barberan, C; Correa Bravo, S; Davis, A; Drapkin, J; Fassassi, C; Gerges, L; Gohel, A; Hossain, R; Likourezos, A; Motov, S; Niceforo, P; Silver, M, 2022)
"The Ketamine for Acute Pain Management After Trauma (KAPT) with registration # NCT04129086 was registered on October 16, 2019."9.51Ketamine for acute pain after trauma: the KAPT randomized controlled trial. ( Balogh, J; Green, C; Harvin, JA; Kao, LS; Klugh, J; Prater, SJ; Puzio, TJ; Sergot, PB; Stephens, CT; Wade, CE; Wandling, MW, 2022)
"Low-dose ketamine might have higher or equivalent efficacy and safety when compared to opioids for managing acute pain among patients presenting to the emergency setting."9.41Efficacy of Low-dose Ketamine for Control of Acute Pain in the Emergency Setting: A Systematic Review and Meta-analysis of Randomized Controlled Trials. ( Ying, M; Zuo, Y, 2023)
"Ketamine is an N-methyl-D-aspartate receptor (NMDA) antagonist used widely as an intravenous analgesic for treatment of acute pain."9.41Efficacy and Tolerability of Oral Compared with Sublingual Ketamine Lozenges as Rescue Analgesics in Adults for Acute Pain: The OSKet Trial. ( Chong, CC; Schug, SA, 2021)
"To evaluate the effectiveness of a subanaesthetic single-dose ketamine (SDK) as an adjunct to opioids for acute pain in emergency department (ED) settings."9.41Subanaesthetic single-dose ketamine as an adjunct to opioid analgesics for acute pain management in the emergency department: a systematic review and meta-analysis. ( Fjendbo Galili, S; Nikolajsen, L; Papadomanolakis-Pakis, N, 2023)
"Given that combinations of morphine with low doses of ketamine in patients with renal colic pain causes more pain and morphine consumption reduction then this combination is suggested as an alternative treatment that could be utilized in patients with renal colic."9.27Can low-dose of ketamine reduce the need for morphine in renal colic? A double-blind randomized clinical trial. ( Abbasi, S; Bidi, N; Farsi, D; Hafezimoghadam, P; Mahshidfar, B; Mofidi, M; Rezai, M, 2018)
"Ketamine PCA led to lower cumulative opioid consumption and lower oxygen supplementation requirements, though hallucinations occurred more frequently with use of ketamine."9.27Ketamine versus hydromorphone patient-controlled analgesia for acute pain in trauma patients. ( Branson, RD; Droege, CA; Droege, ME; Ernst, N; Gerlach, TW; Johannigman, JA; Mueller, EW; Robinson, BRH; Takieddine, SC; Webb, M, 2018)
" The evidence generated by this study is that ketamine is non-inferior to opioids (morphine and fentanyl) in controlling acute pain in children."9.22The Effectiveness of Ketamine Compared to Opioid Analgesics for management of acute pain in Children in The Emergency Department: systematic Review. ( Alanazi, E, 2022)
"To compare the maximum change in numeric rating scale (NRS) pain scores, in patients receiving low-dose ketamine (LDK) or morphine (MOR) for acute pain in the emergency department."9.20Low-dose ketamine vs morphine for acute pain in the ED: a randomized controlled trial. ( Bebarta, VS; Ganem, VJ; Miller, JP; Schauer, SG, 2015)
"Low-dose ketamine has been used perioperatively for pain control and may be a useful adjunct to intravenous (IV) opioids in the control of acute pain in the emergency department (ED)."9.19Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial. ( Beaudoin, FL; Guan, W; Lin, C; Merchant, RC, 2014)
"The aim was to review current evidence regarding the off-label use of intranasal ketamine for acute pain presenting in the setting of the emergency department, and secondary to pediatric limb injuries, renal colic, digital nerve block, and migraines."9.12Intranasal Ketamine for Acute Pain. ( Rocchio, RJ; Ward, KE, 2021)
"There may be a role of IN ketamine for acute pain management in adults in an emergency setting."9.12Efficacy of intranasal ketamine for acute pain management in adults: a systematic review and meta-analysis. ( Hua, GC; Li, X; Peng, F, 2021)
"There has been increased interest in the use of low-dose ketamine (LDK) as an alternative analgesic for the management of acute pain in the emergency department (ED)."9.12Low-dose Ketamine For Acute Pain Control in the Emergency Department: A Systematic Review and Meta-analysis. ( Balzer, N; Grewal, K; McLeod, SL; Walsh, C, 2021)
"Intranasal ketamine has not been well studied in acute pain treatment and does not have a recognized place in therapy in current practice guidelines for pediatric patients."9.05Intranasal Ketamine for Treatment of Acute Pain in Pediatrics: A Systematic Review. ( Beckett, RD; Ferguson, CL, 2020)
"To assess the efficacy and safety of intranasal analgesic-dose ketamine as compared to intranasal fentanyl for pediatric acute pain."9.05Intranasal ketamine for acute pain management in children: A systematic review and meta-analysis. ( Anderson, JL; Bellolio, F; Homme, JL; Lee, JY; Oliveira J E Silva, L, 2020)
"Ketamine has been studied as an alternative to opioids for acute pain in the emergency department setting."9.01Hot Off the Press: A Systematic Review And Meta-analysis of Ketamine as an Alternative to Opioids for Acute Pain in the Emergency Department. ( Bond, C; Heitz, C; Milne, WK; Morgenstern, J, 2019)
"To evaluate the efficacy and safety of perioperative intravenous ketamine in adult patients when used for the treatment or prevention of acute pain following general anaesthesia."8.98Perioperative intravenous ketamine for acute postoperative pain in adults. ( Bell, RF; Brinck, EC; Heesen, M; Kontinen, V; Moore, RA; Straube, S; Tiippana, E, 2018)
"Ketamine is noninferior to morphine for the control of acute pain, indicating that ketamine can be considered as an alternative to opioids for ED short-term pain control."8.98A Systematic Review and Meta-analysis of Ketamine as an Alternative to Opioids for Acute Pain in the Emergency Department. ( Carpenter, CR; Colditz, GA; Doering, M; Karlow, N; Miller, J; Motov, S; Schlaepfer, CH; Schwarz, ES; Stoll, CRT, 2018)
"A short cut review was carried out to establish whether low-dose ketamine is better than morphine at safely and effectively reducing pain scores in ED patients with acute pain who do not respond to conventional therapies."8.93BET 2: Low-dose ketamine for acute pain in the ED. ( Duncan, C; Riley, B, 2016)
"Subdissociative-dose ketamine (low-dose ketamine) is effective and safe to use alone or in combination with opioid analgesics for the treatment of acute pain in the ED."8.93Is There a Role for Intravenous Subdissociative-Dose Ketamine Administered as an Adjunct to Opioids or as a Single Agent for Acute Pain Management in the Emergency Department? ( Motov, S; Nakajima, Y; Rosenbaum, S; Vilke, GM, 2016)
"This multi-center, retrospective cohort study evaluated adult patients who received analgesic and sub-dissociative dose ketamine for the management of acute pain between May 5, 2018, and August 30, 2021, in 21 emergency departments at academic, community, and critical access hospitals across four states."8.31Efficacy of analgesic and sub-dissociative dose ketamine for acute pain in the emergency department. ( Beaudrie-Nunn, AN; Bellolio, F; Canterbury, EA; Mara, KC; Wieruszewski, ED; Woods, EJ, 2023)
"A subanesthetic intravenous ketamine infusion is a safe and effective acute pain management modality for moderate to severely painful surgical procedures and may be useful in patients who are at increased risk for opioid-related adverse events."8.31Implementing an intravenous ketamine protocol for acute pain in the medical-surgical setting. ( Fretwell, D; Hunter, OO; Lu, A; Mariano, ER, 2023)
"Ketamine is known for its antinociceptive effect and is also used for treatment-resistant depression."8.31Intranasal (2R, 6R)-hydroxynorketamine for acute pain: Behavioural and neurophysiological safety analysis in mice. ( Aleem, M; Goswami, N; Manda, K, 2023)
"Managing severe acute nociceptive pain in buprenorphine-maintained individuals for opioid use disorder management is challenging owing to the high affinity and very slow dissociation of buprenorphine from μ-opioid receptors that hinders the use of full agonist opioid analgesics."7.96Efficacy of multimodal analgesic treatment of severe traumatic acute pain in mice pretreated with chronic high dose of buprenorphine inducing mechanical allodynia. ( Bounes, V; Coutens, B; Derreumaux, C; Frances, B; Guiard, BP; Labaste, F; Minville, V; Moulédous, L; Roussin, A, 2020)
"Ketamine infusions have been used for decades to treat acute pain, but a recent surge in usage has made the infusions a mainstay of treatment in emergency departments, in the perioperative period in individuals with refractory pain, and in opioid-tolerant patients."7.88Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists. ( Bhatia, A; Buvanendran, A; Cohen, SP; Davis, FN; Hooten, WM; Hurley, RW; Narouze, S; Schwenk, ES; Viscusi, ER; Wasan, AD, 2018)
"Before updating the French guidelines on postoperative pain treatment in 2015, the Pain Committee of the French Society of Anaesthesiology and Intensive Care (SFAR) conducted a survey on the medical use of ketamine in France."7.81Ketamine for pain management in France, an observational survey. ( Beloeil, H; Derivaux, B; Martinez, V, 2015)
"Rib fractures are associated with increased mortality, particularly in the elderly."6.90Ketamine infusion for pain control in elderly patients with multiple rib fractures: Results of a randomized controlled trial. ( Boyle, K; Carver, TW; Drescher, KM; Juul, J; Kugler, NW; Paul, JS; Peppard, WJ; Rein, L; Somberg, LB; Szabo, A, 2019)
" We hypothesized that low-dose ketamine, compared to placebo, as an adjunctive treatment to opioids would result in better pain control over 2 hours and greater patient satisfaction with pain control; further, this protocol will result in a lower opioid dosage over 2 hours."6.84Ketamine as an Adjunct to Opioids for Acute Pain in the Emergency Department: A Randomized Controlled Trial. ( Bowers, KJ; Heitz, C; McAllister, KB; Ray, M, 2017)
"In 12 healthy male volunteers the effect of rifampicin versus placebo pretreatment on S-ketamine-induced analgesia and cognition was quantified; the S-ketamine dosage was 20 mg/h for 2 h."6.77Estimation of the contribution of norketamine to ketamine-induced acute pain relief and neurocognitive impairment in healthy volunteers. ( Aarts, L; Dahan, A; Kharasch, E; Niesters, M; Noppers, I; Olofsen, E; Sarton, E, 2012)
"Ketamine was compared with various opioids given alone, and intranasal ketamine given with nitrous oxide was compared with nitrous oxide given alone."6.66Ketamine for the treatment of prehospital acute pain: a systematic review of benefit and harm. ( Dahl Friesgaard, K; Hyldmo, PK; Kongstad, P; Kurola, J; Larsen, R; Magnusson, V; Raatiniemi, L; Rehn, M; Rognås, L; Sandberg, M; Vist, GE, 2020)
"Ketamine is an old anesthetic agent that relieves pain by reducing central sensitization in the central nervous system."6.55Ketamine in the treatment of acute pain. ( Brinck, E; Kontinen, V, 2017)
" Predefined subgroup analyses and meta-regression did not detect significant differences across subgroups, including a dose-response relationship."6.53Ketamine added to morphine or hydromorphone patient-controlled analgesia for acute postoperative pain in adults: a systematic review and meta-analysis of randomized trials. ( Cheng, D; Johnston, B; Kaushal, A; Martin, J; Wang, L; Zhu, F, 2016)
"Ketamine is a well-known anesthetic with its use trailing back to the 1960s."6.52The use of subdissociative-dose ketamine for acute pain in the emergency department. ( Motov, SM; Sin, B; Ternas, T, 2015)
"To compare the analgesic efficacy of ultrasound-guided selective peripheral nerve block (PNB) and sub-dissociative dose ketamine (SDK) for management of acute pain in patients with extremity injuries presenting to the emergency department (ED)."5.69Ultrasound-guided selective peripheral nerve block compared with the sub-dissociative dose of ketamine for analgesia in patients with extremity injuries. ( Behera, SHP; Hansda, U; Mishra, TS; Mohanty, CR; Panda, R; Radhakrishnan, RV; Sahoo, S; Shaji, IM; Topno, N; Varghese, JJ, 2023)
"ketamine has potential advantages over morphine for musculoskeletal pain relief."5.51Non-inferiority of intranasal ketamine compared to intravenous morphine for musculoskeletal pain relief among older adults in an emergency department: a randomised controlled trial. ( Paksophis, T; Sri-On, J; Thong-On, K; Tongbua, S, 2022)
"A short cut review was carried out to establish whether low-dose ketamine is a safe and effective alternative to opioids in ED patients in acute severe pain."5.51BET 2: Safety and efficacy of low-dose ketamine versus opioids for acute pain management in the ED. ( AlSagre, A; BinKharfi, M, 2019)
"The purpose of this study is to investigate if an orally administered combination of aspirin and ketamine will provide better analgesia than a ketamine alone in adult patients presenting to the Emergency Department (ED) with acute musculoskeletal pain."5.51Oral Aspirin/ketamine versus oral ketamine for emergency department patients with acute musculoskeletal pain. ( Barberan, C; Correa Bravo, S; Davis, A; Drapkin, J; Fassassi, C; Gerges, L; Gohel, A; Hossain, R; Likourezos, A; Motov, S; Niceforo, P; Silver, M, 2022)
" S(+)-ketamine is an N-methyl-D-aspartic acid (NMDA) receptor antagonist with a strong analgesic effect and can significantly relieve postoperative acute pain and reduce opioid consumption."5.51Evaluation of the effect of perioperative administration of S(+)-ketamine hydrochloride injection for postoperative acute pain in children: study protocol for a prospective, multicenter, randomized, open-label, parallel-group, pragmatic clinical trial. ( Chen, P; Duan, C; Lan, C; Mi, W; Qu, S; Sun, Y; Wang, H; Yang, L; Zhang, J; Zhou, L, 2022)
"The Ketamine for Acute Pain Management After Trauma (KAPT) with registration # NCT04129086 was registered on October 16, 2019."5.51Ketamine for acute pain after trauma: the KAPT randomized controlled trial. ( Balogh, J; Green, C; Harvin, JA; Kao, LS; Klugh, J; Prater, SJ; Puzio, TJ; Sergot, PB; Stephens, CT; Wade, CE; Wandling, MW, 2022)
" The primary objective of this pilot study is to determine if multiple dosing over a three-day perioperative period with oral ketamine is a safe treatment method for acute pain after amputation surgery."5.48Oral Ketamine for Acute Pain Management After Amputation Surgery. ( Buvanendran, A; Kroin, JS; Moric, M; Rajagopal, A; Robison, SJ; Tuman, KJ, 2018)
" This study aims to evaluate the use of topical ketamine in acute pain reduction by directly comparing it to lidocaine-prilocaine (EMLA) cream."5.41Topical ketamine as a local anesthetic agent in reducing venipuncture pain: A randomized controlled trial. ( Golshani, K; Heydari, F; Khalilian, S; Majidinejad, S; Masoumi, B; Massoumi, A, 2021)
"3 mg/kg over 15 min provides analgesic efficacy comparable to morphine for short-term treatment of acute pain in the geriatric ED patients but results in higher rates of psychoperceptual adverse effects."5.30Intravenous subdissociative-dose ketamine versus morphine for acute geriatric pain in the Emergency Department: A randomized controlled trial. ( Brady, J; Butt, M; Drapkin, J; Flom, P; Fromm, C; Gohel, A; Likourezos, A; Mai, M; Mann, S; Marshall, J; Motov, S; Rothberger, N; Yetter, E, 2019)
"Given that combinations of morphine with low doses of ketamine in patients with renal colic pain causes more pain and morphine consumption reduction then this combination is suggested as an alternative treatment that could be utilized in patients with renal colic."5.27Can low-dose of ketamine reduce the need for morphine in renal colic? A double-blind randomized clinical trial. ( Abbasi, S; Bidi, N; Farsi, D; Hafezimoghadam, P; Mahshidfar, B; Mofidi, M; Rezai, M, 2018)
"Ketamine PCA led to lower cumulative opioid consumption and lower oxygen supplementation requirements, though hallucinations occurred more frequently with use of ketamine."5.27Ketamine versus hydromorphone patient-controlled analgesia for acute pain in trauma patients. ( Branson, RD; Droege, CA; Droege, ME; Ernst, N; Gerlach, TW; Johannigman, JA; Mueller, EW; Robinson, BRH; Takieddine, SC; Webb, M, 2018)
" Although low-dose ketamine demonstrates analgesic efficacy for acute pain complaints in the ED, headaches have historically been excluded from these trials."5.27Low-dose Ketamine Does Not Improve Migraine in the Emergency Department: A Randomized Placebo-controlled Trial. ( Bos, L; Etchison, AR; Heitz, C; McAllister, KB; Mohammed, M; Park, B; Phan, AV; Ray, M, 2018)
"5 μg/kg intranasal fentanyl in children 4 to 17 years old with acute pain from suspected isolated extremity fractures presenting to an urban Level II pediatric trauma center from December 2015 to November 2016."5.24Randomized Controlled Feasibility Trial of Intranasal Ketamine Compared to Intranasal Fentanyl for Analgesia in Children with Suspected Extremity Fractures. ( Bryant, KK; Dunn, C; Hogg, M; Moore, CG; Reynolds, SL; Runyon, MS; Studnek, JR; Templin, MA; Walker, KR; Young, JR, 2017)
"Compare adverse effects and analgesic efficacy of low-dose ketamine for acute pain in the ED administered either by single intravenous push (IVP) or short infusion (SI)."5.24A prospective randomized, double-dummy trial comparing IV push low dose ketamine to short infusion of low dose ketamine for treatment of  pain in the ED. ( Brady, J; Drapkin, J; Fromm, C; Homel, P; Likourezos, A; Mai, M; Motov, S; Pushkar, I; Yasavolian, M, 2017)
" The evidence generated by this study is that ketamine is non-inferior to opioids (morphine and fentanyl) in controlling acute pain in children."5.22The Effectiveness of Ketamine Compared to Opioid Analgesics for management of acute pain in Children in The Emergency Department: systematic Review. ( Alanazi, E, 2022)
"Primary outcomes were postoperative acute pain at rest/during movement after 24 h and number of patients with ketamine-related adverse events."5.22Perioperative ketamine for postoperative pain management in patients with preoperative opioid intake: A systematic review and meta-analysis. ( Kranke, P; Lipke, E; Meyer-Frießem, CH; Pogatzki-Zahn, EM; Reichl, S; Schnabel, A; Weibel, S; Zahn, PK, 2022)
"3 mg/kg provides analgesic effectiveness and apparent safety comparable to that of intravenous morphine for short-term treatment of acute pain in the ED."5.20Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial. ( Cohen, V; Fromm, C; Homel, P; Likourezos, A; McKay, C; Motov, S; Pushkar, I; Rockoff, B; Soleyman-Zomalan, E; Terentiev, V, 2015)
"Low-dose ketamine combined with a reduced dose hydromorphone protocol produced rapid, profound pain relief without significant side effects in a diverse cohort of ED patients with acute pain."5.17Effective analgesia with low-dose ketamine and reduced dose hydromorphone in ED patients with severe pain. ( Ahern, TL; Frazee, BW; Herring, AA; Stone, MB, 2013)
"To assess the efficacy and safety of intranasal analgesic-dose ketamine as compared to intranasal fentanyl for pediatric acute pain."5.05Intranasal ketamine for acute pain management in children: A systematic review and meta-analysis. ( Anderson, JL; Bellolio, F; Homme, JL; Lee, JY; Oliveira J E Silva, L, 2020)
"Ketamine is noninferior to morphine for the control of acute pain, indicating that ketamine can be considered as an alternative to opioids for ED short-term pain control."4.98A Systematic Review and Meta-analysis of Ketamine as an Alternative to Opioids for Acute Pain in the Emergency Department. ( Carpenter, CR; Colditz, GA; Doering, M; Karlow, N; Miller, J; Motov, S; Schlaepfer, CH; Schwarz, ES; Stoll, CRT, 2018)
"To evaluate the efficacy and safety of perioperative intravenous ketamine in adult patients when used for the treatment or prevention of acute pain following general anaesthesia."4.98Perioperative intravenous ketamine for acute postoperative pain in adults. ( Bell, RF; Brinck, EC; Heesen, M; Kontinen, V; Moore, RA; Straube, S; Tiippana, E, 2018)
"The aim of the study is to determine the performance of low-dose ketamine (LDK) as an analgesic for acute pain management in adult patients in the emergency department (ED)."4.98Systematic review of the use of low-dose ketamine for analgesia in the emergency department. ( Clark, E; Ghate, G; Vaillancourt, C, 2018)
"A short cut review was carried out to establish whether low-dose ketamine is better than morphine at safely and effectively reducing pain scores in ED patients with acute pain who do not respond to conventional therapies."4.93BET 2: Low-dose ketamine for acute pain in the ED. ( Duncan, C; Riley, B, 2016)
"Ketamine is known for its antinociceptive effect and is also used for treatment-resistant depression."4.31Intranasal (2R, 6R)-hydroxynorketamine for acute pain: Behavioural and neurophysiological safety analysis in mice. ( Aleem, M; Goswami, N; Manda, K, 2023)
"This multi-center, retrospective cohort study evaluated adult patients who received analgesic and sub-dissociative dose ketamine for the management of acute pain between May 5, 2018, and August 30, 2021, in 21 emergency departments at academic, community, and critical access hospitals across four states."4.31Efficacy of analgesic and sub-dissociative dose ketamine for acute pain in the emergency department. ( Beaudrie-Nunn, AN; Bellolio, F; Canterbury, EA; Mara, KC; Wieruszewski, ED; Woods, EJ, 2023)
"Ketamine, adverse effects, tachycardia, hypertension, postoperative pain, chronic postsurgical pain."4.31Effect of Analgesic Low-Dose Ketamine Infusions on the Cardiovascular Response: A Retrospective Analysis. ( Cadavid, AM; Calle, E; Camelo, JE; Casas, FD; Ramirez, CD; Tovar, A; Visbal, K, 2023)
" The acute pain group did not show an opioid reduction associated with the ketamine infusions."4.12Low-dose ketamine infusions reduce opioid use in pediatric and young adult oncology patients. ( Anghelescu, DL; Li, Y; Morgan, KJ; Patni, T; Ryan, S; Wu, D, 2022)
"Managing severe acute nociceptive pain in buprenorphine-maintained individuals for opioid use disorder management is challenging owing to the high affinity and very slow dissociation of buprenorphine from μ-opioid receptors that hinders the use of full agonist opioid analgesics."3.96Efficacy of multimodal analgesic treatment of severe traumatic acute pain in mice pretreated with chronic high dose of buprenorphine inducing mechanical allodynia. ( Bounes, V; Coutens, B; Derreumaux, C; Frances, B; Guiard, BP; Labaste, F; Minville, V; Moulédous, L; Roussin, A, 2020)
"Guidelines issued by the American Society of Regional Anesthesia and Pain Medicine suggest that ketamine infusions for acute pain management are advantageous as a primary treatment or as an opioid adjunct."3.91Subanesthetic ketamine infusions for the management of pediatric pain in non-critical care settings: An observational analysis. ( Fernandez, PG; Lee, J; Masaracchia, MM; Sites, BD; Thomas, JJ, 2019)
"Before updating the French guidelines on postoperative pain treatment in 2015, the Pain Committee of the French Society of Anaesthesiology and Intensive Care (SFAR) conducted a survey on the medical use of ketamine in France."3.81Ketamine for pain management in France, an observational survey. ( Beloeil, H; Derivaux, B; Martinez, V, 2015)
"Unit medical protocols authorize ketamine for tourniquet pain, amputations, long-bone fractures, and pain refractory to other agents."3.80Prehospital analgesia with ketamine for combat wounds: a case series. ( Conklin, CC; Fisher, AD; Mabry, RL; Rippee, B; Shehan, H, 2014)
"The data suggest that the combination of metoclopramide and ketamine synergistically controls acute pain in mice."3.78Antinociception by metoclopramide, ketamine and their combinations in mice. ( Al-Baggou, BKh; Mohammad, FK; Naser, AS, 2012)
"We aimed to assess and compare the analgesic efficacies and adverse effects of ketamine administered through a breath-actuated nebulizer at 3 different dosing regimens for emergency department patients presenting with acute and chronic painful conditions."3.01Comparison of Nebulized Ketamine at Three Different Dosing Regimens for Treating Painful Conditions in the Emergency Department: A Prospective, Randomized, Double-Blind Clinical Trial. ( Butt, M; Davis, A; Dove, D; Drapkin, J; Fassassi, C; Favale, P; Gohel, A; Hossain, R; Kabariti, S; Likourezos, A; Marshall, J; Motov, S; Silver, M, 2021)
"Ketamine has the optimal characteristics for use in an Emergency Department."3.01[Ketamine for medically-delegated analgesia in the Emergency Department]. ( Della Santa, V; Heymann, EP; Jardot, F; Petreska, I, 2023)
"Rib fractures are associated with increased mortality, particularly in the elderly."2.90Ketamine infusion for pain control in elderly patients with multiple rib fractures: Results of a randomized controlled trial. ( Boyle, K; Carver, TW; Drescher, KM; Juul, J; Kugler, NW; Paul, JS; Peppard, WJ; Rein, L; Somberg, LB; Szabo, A, 2019)
"Acute pain is a common condition among prehospital patients and prompt management is pivotal."2.87Is intravenously administered, subdissociative-dose KETAmine non-inferior to MORPHine for prehospital analgesia (the KETAMORPH study): study protocol for a randomized controlled trial. ( Auffret, Y; Brenckmann, V; Broch, H; Deciron, F; Ecoffey, C; Fradin, P; Hardouin, JB; Javaudin, F; Jenvrin, J; Kabbaj, A; Lariby, S; Le Bastard, Q; Le Cornec, C; Le Pottier, M; Longo, C; Montassier, E, 2018)
"Ketamine is an effective and safe multimodal analgesic in patients undergoing breast surgery, administered both intravenously and when added to bupivacaine in paravertebral blocks."2.72The Effect of Ketamine on Acute and Chronic Wound Pain in Patients Undergoing Breast Surgery: A Meta-Analysis and Systematic Review. ( Bi, Y; Liu, B; Ma, J; Ye, Y; Zhang, X; Zhu, Y, 2021)
" Predefined subgroup analyses and meta-regression did not detect significant differences across subgroups, including a dose-response relationship."2.53Ketamine added to morphine or hydromorphone patient-controlled analgesia for acute postoperative pain in adults: a systematic review and meta-analysis of randomized trials. ( Cheng, D; Johnston, B; Kaushal, A; Martin, J; Wang, L; Zhu, F, 2016)
"Ketamine is a well-known anesthetic with its use trailing back to the 1960s."2.52The use of subdissociative-dose ketamine for acute pain in the emergency department. ( Motov, SM; Sin, B; Ternas, T, 2015)
"Recent awareness that chronic pain may occur after childbirth has prompted clinicians and researchers to investigate this topic."2.49Chronic pain after childbirth. ( Bollag, L; Landau, R; Ortner, C, 2013)
"The aim of this study is to assess the current situation in out of hospital pain management in Germany regarding the substances, indications, dosage and the delegation of the use of analgesics to emergency medical service (EMS) staff."1.91Application of analgesics in emergency services in Germany: a survey of the medical directors. ( Scharonow, M; Scharonow, O; Vilcane, S; Weilbach, C, 2023)
"Currently, the treatment of SCD acute pain only targets its symptoms, rather than underlying mechanisms, and is directed by expert and consensus guidelines."1.72Subanesthetic ketamine: the way forward for pain management in sickle cell disease patients? ( Carullo, V; Nobrega, R; Quezado, ZMN; Thein, SL, 2022)
"Acetaminophen was mixed with all 18 solutions and was examined at time 0, 15, 30, and 60 min."1.72Compatibility of intravenous acetaminophen with morphine, fentanyl and ketamine in acute pediatric pain setting. ( Chan, MTV; Cheaib, A; O'Loughlin, E; Peng, YG; Williams, R, 2022)
"Ketamine is a noncompetitive N-methyl-D-aspartate/glutamate receptor complex antagonist that decreases pain by diminishing central sensitization and hyperalgesia."1.62Nebulized Ketamine Used for Pain Management of Orthopedic Trauma. ( Davis, AR; Dove, D; Fassassi, C; Khordipour, E; Motov, S; Ranginwala, A, 2021)
"Fentanyl was most frequently used for APT (n = 19)."1.51Intranasal Analgesia and Sedation in Pediatric Emergency Care-A Prospective Observational Study on the Implementation of an Institutional Protocol in a Tertiary Children's Hospital. ( Bantel, C; Eich, C; Fieler, M; Jacobsen, N; Nemeth, M; Sümpelmann, R, 2019)
" The primary objective of this pilot study is to determine if multiple dosing over a three-day perioperative period with oral ketamine is a safe treatment method for acute pain after amputation surgery."1.48Oral Ketamine for Acute Pain Management After Amputation Surgery. ( Buvanendran, A; Kroin, JS; Moric, M; Rajagopal, A; Robison, SJ; Tuman, KJ, 2018)

Research

Studies (96)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's55 (57.29)24.3611
2020's41 (42.71)2.80

Authors

AuthorsStudies
Silverstein, WK1
Juurlink, DN1
Zipursky, JS1
Lindbeck, G1
Shah, MI1
Braithwaite, S1
Powell, JR1
Panchal, AR1
Browne, LR1
Lang, ES1
Burton, B1
Coughenour, J1
Crowe, RP1
Degn, H1
Hedges, M1
Gasper, J1
Guild, K1
Mattera, C1
Nasca, S1
Taillac, P1
Warth, M1
Meyer-Frießem, CH1
Lipke, E1
Weibel, S1
Kranke, P1
Reichl, S1
Pogatzki-Zahn, EM1
Zahn, PK1
Schnabel, A1
Moradi, MM2
Safaie, A1
Baratloo, A1
Payandemehr, P1
Tongbua, S1
Sri-On, J1
Thong-On, K1
Paksophis, T1
Anghelescu, DL2
Ryan, S1
Wu, D1
Morgan, KJ2
Patni, T1
Li, Y1
O'Loughlin, E1
Peng, YG1
Cheaib, A1
Chan, MTV1
Williams, R1
Davis, A3
Fassassi, C4
Dove, D3
Drapkin, J5
Likourezos, A6
Gohel, A4
Favale, P2
Hossain, R3
Butt, M3
Gerges, L2
Motov, S10
Kenney, MO1
Becerra, B1
Mallikarjunan, A1
Shah, N1
Smith, WR1
Barberan, C1
Correa Bravo, S1
Silver, M2
Niceforo, P1
Wang, H1
Duan, C1
Zhang, J1
Qu, S1
Sun, Y1
Zhou, L1
Yang, L1
Lan, C1
Mi, W1
Chen, P1
Puzio, TJ1
Klugh, J1
Wandling, MW1
Green, C1
Balogh, J1
Prater, SJ1
Stephens, CT1
Sergot, PB1
Wade, CE1
Kao, LS1
Harvin, JA1
Alanazi, E1
Nobrega, R1
Carullo, V1
Thein, SL1
Quezado, ZMN1
Mohanty, CR1
Varghese, JJ1
Panda, R1
Sahoo, S1
Mishra, TS1
Radhakrishnan, RV1
Topno, N1
Hansda, U1
Shaji, IM1
Behera, SHP1
Hunter, OO1
Lu, A1
Fretwell, D1
Mariano, ER1
Goswami, N1
Aleem, M1
Manda, K1
Fjendbo Galili, S1
Nikolajsen, L1
Papadomanolakis-Pakis, N1
Ying, M1
Zuo, Y1
Beaudrie-Nunn, AN1
Wieruszewski, ED1
Woods, EJ1
Bellolio, F2
Mara, KC1
Canterbury, EA1
Vilcane, S1
Scharonow, O1
Weilbach, C1
Scharonow, M1
Cadavid, AM1
Casas, FD1
Camelo, JE1
Tovar, A1
Ramirez, CD1
Calle, E1
Visbal, K1
Jardot, F1
Petreska, I1
Della Santa, V1
Heymann, EP1
Michelet, F1
Smyth, M1
Lall, R1
Noordali, H1
Starr, K1
Berridge, L1
Yeung, J1
Fuller, G1
Petrou, S1
Walker, A1
Mark, J1
Canaway, A1
Khan, K1
Perkins, GD1
Kugler, NW2
Carver, TW2
Juul, J2
Peppard, WJ2
Boyle, K1
Drescher, KM2
Szabo, A2
Rein, L1
Somberg, LB2
Paul, JS2
Coutens, B1
Derreumaux, C1
Labaste, F1
Minville, V1
Guiard, BP1
Moulédous, L1
Bounes, V1
Roussin, A1
Frances, B1
Savage, T1
Polsky, Z1
Ross, M1
Bouida, W1
Bel Haj Ali, K1
Ben Soltane, H1
Msolli, MA1
Boubaker, H1
Sekma, A1
Beltaief, K1
Grissa, MH1
Methamem, M1
Boukef, R1
Belguith, A1
Nouira, S1
Ferguson, CL1
Beckett, RD1
Oliveira J E Silva, L1
Lee, JY1
Homme, JL1
Anderson, JL1
Balzer, N1
McLeod, SL1
Walsh, C1
Grewal, K1
Bi, Y1
Ye, Y1
Zhu, Y1
Ma, J1
Zhang, X1
Liu, B1
Sandberg, M1
Hyldmo, PK1
Kongstad, P1
Dahl Friesgaard, K1
Raatiniemi, L1
Larsen, R1
Magnusson, V1
Rognås, L1
Kurola, J1
Rehn, M1
Vist, GE1
Davis, AR1
Ranginwala, A1
Khordipour, E1
Lovett, S1
Reed, T1
Riggs, R1
Lew, G1
Koch, E1
Durazo-Arvizu, RA1
Rech, MA1
Rocchio, RJ1
Ward, KE1
Li, C1
Doellner, C1
Leis, A1
Marinkovic, A1
Gibbons, K1
Wagner, D1
Heydari, F1
Khalilian, S1
Golshani, K1
Majidinejad, S1
Masoumi, B1
Massoumi, A1
Li, X1
Hua, GC1
Peng, F1
Kabariti, S1
Marshall, J2
Chong, CC1
Schug, SA1
Alshahrani, MS2
AlSulaibikh, AH1
ElTahan, MR1
AlFaraj, SZ1
Asonto, LP2
AlMulhim, AA1
AlAbbad, MF1
Almaghraby, N2
AlJumaan, MA1
AlJunaid, TO1
Darweesh, MN1
AlHawaj, FM1
Mahmoud, AM2
Alossaimi, BK2
Alotaibi, SK2
AlMutairi, TM2
AlSulaiman PharmD, DA1
Alfaraj, D2
Alhawwas, R1
Mbuagbaw, L1
Lewis, K1
Verhovsek, M1
Crowther, M1
Guyatt, G1
Alhazzani, W2
Ghate, G1
Clark, E1
Vaillancourt, C1
Abbasi, S1
Bidi, N1
Mahshidfar, B1
Hafezimoghadam, P1
Rezai, M1
Mofidi, M1
Farsi, D1
Reynolds, SL1
Bryant, KK1
Studnek, JR1
Hogg, M1
Dunn, C1
Templin, MA1
Moore, CG1
Young, JR1
Walker, KR1
Runyon, MS1
Buvanendran, A2
Kroin, JS1
Rajagopal, A1
Robison, SJ1
Moric, M1
Tuman, KJ1
Brinck, E1
Kontinen, V2
Takieddine, SC1
Droege, CA1
Ernst, N1
Droege, ME1
Webb, M1
Branson, RD1
Gerlach, TW1
Robinson, BRH1
Johannigman, JA1
Mueller, EW1
Le Cornec, C1
Lariby, S1
Brenckmann, V1
Hardouin, JB1
Ecoffey, C1
Le Pottier, M1
Fradin, P1
Broch, H1
Kabbaj, A1
Auffret, Y1
Deciron, F1
Longo, C1
Javaudin, F1
Le Bastard, Q1
Jenvrin, J1
Montassier, E1
Weingarten, TN1
Taenzer, AH1
Elkassabany, NM1
Le Wendling, L1
Nin, O1
Kent, ML1
Lubega, FA1
DeSilva, MS1
Munube, D1
Nkwine, R1
Tumukunde, J1
Agaba, PK1
Nabukenya, MT1
Bulamba, F1
Luggya, TS1
Mann, S1
Yetter, E1
Brady, J2
Rothberger, N1
Flom, P1
Mai, M2
Fromm, C3
Schwenk, ES1
Viscusi, ER1
Hurley, RW1
Wasan, AD1
Narouze, S1
Bhatia, A1
Davis, FN1
Hooten, WM1
Cohen, SP1
Breivik, H1
Zeballos, JL1
Lirk, P1
Rathmell, JP1
Karlow, N1
Schlaepfer, CH1
Stoll, CRT1
Doering, M1
Carpenter, CR1
Colditz, GA1
Miller, J1
Schwarz, ES1
Yin, Z1
Etchison, AR1
Bos, L1
Ray, M2
McAllister, KB2
Mohammed, M1
Park, B1
Phan, AV1
Heitz, C3
Morgenstern, J1
Bond, C1
Milne, WK1
Brinck, EC1
Tiippana, E1
Heesen, M1
Bell, RF1
Straube, S1
Moore, RA1
BinKharfi, M1
AlSagre, A1
Davison, SN1
Thompson, T1
Whiter, F1
Gallop, K1
Veronese, N1
Solmi, M1
Newton, P1
Stubbs, B1
Andolfatto, G1
Innes, K1
Dick, W1
Jenneson, S1
Willman, E1
Stenstrom, R1
Zed, PJ1
Benoit, G1
El Tahan, MM1
Al Sulaibikh, AH1
Al Faraj, SZ1
Al Mulhim, AA1
Al Abbad, MF1
Al Nahhash, SA1
Aldarweesh, MN1
Al Jumaan, MA1
Al Junaid, TO1
Al Hawaj, FM1
AlKenany, S1
ElSayed, OF1
Abdelwahab, HM1
Moussa, MM1
AlSulaiman, DA1
Al Shahrani, SD1
Puri, L1
Masaracchia, MM1
Sites, BD1
Lee, J1
Thomas, JJ1
Fernandez, PG1
Landau, R1
Bollag, L1
Ortner, C1
Ahern, TL2
Herring, AA2
Stone, MB1
Frazee, BW2
Jennings, CA1
Bobb, BT1
Noreika, DM1
Coyne, PJ1
Vaid, P1
McCartney, CJ1
Nelligan, K1
Russell, KW1
Scaife, CL1
Weber, DC1
Windsor, JS1
Wheeler, AR1
Smith, W1
Wedmore, I1
McIntosh, SE1
Lieberman, JR1
Beaudoin, FL1
Lin, C1
Guan, W1
Merchant, RC1
Fisher, AD1
Rippee, B1
Shehan, H1
Conklin, CC1
Mabry, RL1
Goltser, A1
Soleyman-Zomalan, E2
Kresch, F1
Anderson, ES1
Madia, VA1
Fahimi, J1
Miller, JP1
Schauer, SG1
Ganem, VJ1
Bebarta, VS1
Sin, B1
Ternas, T1
Motov, SM2
Rockoff, B1
Cohen, V1
Pushkar, I2
McKay, C1
Homel, P2
Terentiev, V1
Yetim, M1
Tekindur, S1
Eyi, YE1
Barrett, TW1
Schriger, DL1
Banting, J1
Beriano, T1
Radvansky, BM1
Shah, K1
Parikh, A1
Sifonios, AN1
Le, V1
Eloy, JD1
Martinez, V1
Derivaux, B1
Beloeil, H1
Wang, L1
Johnston, B1
Kaushal, A1
Cheng, D1
Zhu, F1
Martin, J1
Nelson, LS1
Badiola, IJ1
Rosenbaum, S1
Vilke, GM1
Nakajima, Y1
Lee, EN1
Lee, JH1
Duncan, C1
Riley, B1
Nemeth, M1
Jacobsen, N1
Bantel, C1
Fieler, M1
Sümpelmann, R1
Eich, C1
Bowers, KJ1
Yasavolian, M1
Mohammad, FK1
Al-Baggou, BKh1
Naser, AS1
Olofsen, E1
Noppers, I1
Niesters, M1
Kharasch, E1
Aarts, L1
Sarton, E1
Dahan, A1

Clinical Trials (46)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Analgesic Efficacy of Orally Administered VTS-K (Liquid Oral Ketamine Taken Simultaneously With VTS-Aspirin) for Pain Management of Adult ED Patients Presenting to the ED With Acute Musculoskeletal Pain[NCT04702555]25 participants (Actual)Observational2021-01-08Completed
A Comparison of Proprietary Formulations of Oral Ketamine + Aspirin and Oral Ketamine Alone in Adult Patients Presenting to the ED With Acute Musculoskeletal Pain: Prospective, Randomized, Open-Label, Clinical Trial.[NCT04860804]Phase 460 participants (Actual)Interventional2021-04-22Completed
Safety and Efficacy Evaluation of S (+) -Ketamine for Postoperative Acute Pain in Children in Perioperative Settings: A Multicenter, Randomized, Open-label, Active Controlled Pragmatic Clinical Trial[NCT04834427]Phase 43,000 participants (Anticipated)Interventional2021-05-01Not yet recruiting
Ketamine for Acute Pain After Trauma: KAPT Trial[NCT04129086]Phase 4305 participants (Actual)Interventional2020-07-01Completed
Paravertebral Block Versus Simultaneous Ketamine and Lidocaine Infusions for Pain Management in Rib Fracture Patients[NCT04413799]Early Phase 1170 participants (Anticipated)Interventional2020-09-01Recruiting
Pilot Study: Ketamine for Acute Pain After Rattlesnake Envenomation[NCT05379179]Phase 440 participants (Anticipated)Interventional2022-06-20Enrolling by invitation
A Combination Study With Sub-Dissociative Ketamine and Fentanyl to Treat Moderate to Severe Pain in the Emergency Department[NCT03959852]Phase 46 participants (Actual)Interventional2019-11-18Terminated (stopped due to Residency completed.)
Comparison of Ketamine 0.1 mg/kg, 0.2 mg/kg, and 0.3 mg/kg Intravenous Doses for Acute Pain in the Emergency Department: A Prospective, Randomized, Double-blind, Active-controlled, Clinical Trial[NCT03896230]Phase 411 participants (Actual)Interventional2019-05-03Terminated (stopped due to Due to resource limitations the study was on hold and was then terminated.)
A Prospective, Open-Label Pilot Clinical Trial of Oral Ketamine for Acute Pain Management After Amputation Surgery[NCT02341963]Phase 15 participants (Actual)Interventional2015-01-31Terminated (stopped due to Recruitment issues)
Ketamine Patient-Controlled Analgesia for Acute Pain in Native Airway Multiple and Orthopedic Trauma Patients: A Randomized, Active Comparator, Blinded Trial[NCT02062879]Phase 320 participants (Actual)Interventional2014-04-30Terminated (stopped due to Withdrawals from study due to anticipated effects from study drugs)
Intravenous Subdissociative-dose Ketamine Versus Morphine for Prehospital Analgesia a Randomized Controlled Trial[NCT03236805]Phase 3285 participants (Actual)Interventional2017-11-23Terminated (stopped due to 285 patients have recruited instead on 496 but we don't want to continue to prolonge the study. Analysis will be performed on the data we have.)
A Pilot Study of the Use of Oral Ketamine for Treatment of Vaso-Occlusive Pain in Adolescents and Young Adults[NCT05378555]Phase 310 participants (Anticipated)Interventional2023-05-01Recruiting
Low-dose Ketamine Versus Morphine for Severe Painful Sickle Cell Crises in Children at Mulago Hospital: A Randomised Controlled Trial[NCT02434939]Phase 4240 participants (Actual)Interventional2015-06-30Completed
Low-Dose Ketamine Versus Morphine for Moderate to Severe Pain in the Emergency Department Geriatric Population: A Prospective, Randomized, Double-Blind Study.[NCT02673372]Phase 460 participants (Actual)Interventional2016-04-30Completed
Ketamine for Refractory Chronic Migraine: a Pilot Study[NCT03896256]Early Phase 16 participants (Actual)Interventional2019-03-22Completed
The Effect of Low-dose of S-ketamine Combined With Sufentanil for Postoperative Patient-controlled Intravenous Analgesia in Patients Following Cesarean Section[NCT05299866]Phase 4216 participants (Anticipated)Interventional2022-04-12Recruiting
Effect of Mini-dose Dexmedetomidine-Esketamine Infusion on Sleep Quality in Older Patients Undergoing Knee or Hip Replacement Surgery: A Multicenter Randomized Controlled Trial[NCT05950646]Phase 4154 participants (Anticipated)Interventional2023-11-01Recruiting
The Effect of Intraoperative Lidocaine Infusion and Intraoperative Lidocaine Combined With Ketamine Infusion on Opioid Consumption After Laparoscopic Bariatric Surgery: A Randomized Controlled Trial[NCT04524130]Phase 487 participants (Anticipated)Interventional2021-04-01Active, not recruiting
(2R,6R)-Hydroxynorketamine a Novel Therapeutic Analgesic for the Treatment of Neuropathic Pain: A Randomized Double Blind Cross-Over Trial.[NCT05864053]Phase 1/Phase 225 participants (Anticipated)Interventional2024-01-31Not yet recruiting
Efficacy of Different Dose Esketamine and Dexmedetomidine Combination for Supplemental Analgesia After Scoliosis Correction Surgery: A Randomized, Double-blind Trial[NCT06062550]Phase 4312 participants (Anticipated)Interventional2023-10-31Not yet recruiting
Impact of Different Dose Esketamine and Dexmedetomidine Combination for Supplemental Analgesia on Long-term Outcomes After Scoliosis Correction Surgery: Follow-up of a Randomized Trial[NCT06087510]Phase 4312 participants (Anticipated)Interventional2024-01-31Not yet recruiting
The Effect and Contribution of a Perioperative Ketamine Infusion in an Established Enhanced Recovery Pathway[NCT04625283]Phase 41,544 participants (Anticipated)Interventional2021-04-12Enrolling by invitation
Patient Satisfaction With Subdissociative Dose Ketamine Versus Morphine for Emergency Department Pain Control[NCT04698772]32 participants (Actual)Observational2019-12-19Completed
Dexmedotomidine for Acute Pain Control in Patients With Multiple Rib Fractures[NCT05321121]Phase 460 participants (Anticipated)Interventional2021-11-12Recruiting
Ketamine Infusion Therapy for the Management of Acute Pain in Adult Rib Fracture Patients[NCT02432456]Phase 4153 participants (Actual)Interventional2015-09-30Completed
Analgesic Effects of Low-dose S-ketamine in Patients Undergoing Major Spine Fusion Surgery: A Double-blinded, Randomized Controlled Trial[NCT04964219]Phase 4164 participants (Anticipated)Interventional2022-02-08Recruiting
Low-dose S-ketamine and Dexmedetomidine in Combination With Opioids for Patient-controlled Analgesia After Scoliosis Correction Surgery: a Randomized, Double-blind, Placebo-controlled Trial[NCT04791059]Phase 4200 participants (Actual)Interventional2021-04-09Completed
Observational Study of the Efficacy of Ketamine for Rescue Analgesia in the Post Anesthesia Recovery Room[NCT04701008]143 participants (Actual)Observational2020-09-01Completed
Prehospital Analgesia With Intra-Nasal Ketamine[NCT02753114]Phase 4120 participants (Actual)Interventional2017-11-06Completed
Intranasal Ketamine Versus Subcutaneous Ketamine for Treatment of Post Traumatic Acute Pain in the Emergency Department[NCT05229055]Phase 2/Phase 31,000 participants (Anticipated)Interventional2023-04-15Recruiting
Ketamine for Acute Painful Crisis in Sickle Cell Disease Patients: Prospective Randomized Control Trial[NCT03431285]264 participants (Anticipated)Interventional2018-01-01Recruiting
Ketamine For Acute Treatment of Pain in Emergency Department[NCT02306759]Phase 460 participants (Actual)Interventional2015-01-31Completed
Comparing the Effectiveness of Low-dose Ketamine With Morphine to Treat Pain in Patients With Long Bone Fractures[NCT02430818]13 participants (Actual)Interventional2015-04-30Terminated (stopped due to were not able to enroll patients to a satisfactory level)
Low Dose Ketamine as an Adjunct to Opiates for Acute Pain in the Emergency Department[NCT02489630]Phase 4116 participants (Actual)Interventional2013-09-30Completed
Adjuvant Low-dose Ketamine in Pediatric Sickle Cell Vaso-occlusive Crisis (AKTSS)[NCT03296345]Phase 262 participants (Actual)Interventional2016-06-30Completed
Ketamine Infusion for Acute Sickle Cell crisiS in the Emergency Department[NCT02417298]12 participants (Actual)Interventional2015-11-30Terminated (stopped due to Feasibility)
Opioid-Free Shoulder Arthroplasty[NCT03540030]Phase 486 participants (Actual)Interventional2016-09-30Completed
Efficacy and Side Effects of Intrathecal Morphine in Multimodal Analgesia for Unilateral Total Knee Arthroplasty[NCT03232957]131 participants (Actual)Interventional2017-08-01Completed
Effect of Paracetamol and Ibuprofen When Intravenously Given Combination or Alone in Reducing Morphine Requirements After Total Knee Arthroplasty[NCT04414995]Phase 2/Phase 336 participants (Actual)Interventional2020-06-05Completed
ED Treatment of Suicidal Patients With Ketamine Infusion[NCT03502551]Phase 20 participants (Actual)Interventional2019-04-01Withdrawn (stopped due to Trial never received funding.)
A Double Blind, Placebo Controlled, Fixed-Flexible Dose Clinical Trial of Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome[NCT05657860]Phase 433 participants (Anticipated)Interventional2020-12-17Recruiting
Low Dose Ketamine Infusion for Analgesia in the Emergency Department (ED) to Reduce Side Effects: A Double Blind, Double Dummy Randomized Controlled Trial[NCT05518877]Phase 448 participants (Anticipated)Interventional2022-12-07Recruiting
The Check Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine. A Multi-Center, Randomized Double-Blind, Clinical Control Trial.[NCT02657031]Phase 454 participants (Actual)Interventional2016-03-17Completed
An Open-Label Clinical Trial of Simultaneous Administration of Oral Aspirin and Ketamine as Adjunct to Oral Antidepressant Therapy in Treatment-Resistant Depression[NCT05615948]Phase 420 participants (Anticipated)Interventional2022-12-06Recruiting
Cardiovascular and Neuropsychiatric Side Effects in Ketamine Analgesic Infusions in Acute Pain[NCT03979105]300 participants (Actual)Observational2017-07-01Completed
PCA Ketamine-Morphine Versus PCA Morphine as Post-Operative Analgesia in Colorectal Surgery[NCT06021717]Phase 460 participants (Actual)Interventional2018-04-05Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Reduction in Pain Score at 60 Minutes

Reduction of pain scores on numeric rating pain scale (NRS) at 60 minutes mark form the baseline. The NRS is an 11 item Likert Scale ranging from 0 (no pain) to 10 (very severe pain) with 5 indicating moderate pain. (NCT04860804)
Timeframe: 60 minutes

Interventionunits on a scale (Mean)
AOK Group2.18
OK Group4.01

Average Daily Opioid Use as Measured by the Morphine Milligram Equivalents (MME) Per Day

(NCT04129086)
Timeframe: In-hospital days (up to 6 weeks post hospital admission)

InterventionMME per day (Mean)
Ketamine Plus Usual Care32
Usual Care39

Duration of Ketamine Drip

Length of time Ketamine drip was infused (NCT04129086)
Timeframe: Hospital discharge (up to 6 weeks post hospital admission)

Interventionhours (Median)
Ketamine Plus Usual Care60
Usual Care76

Health Status as Assessed by the Euro-QOL EQ-5D-3L Questionnaire (Current Health)

"For this item of the Euro-QOL EQ-5D-3L questionnaire, participants are asked the question How would you rate your health today?, and they respond with a score from 0 - 100, with a higher score indicating a better outcome." (NCT04129086)
Timeframe: 6 months post admission

Interventionscore on a scale (Median)
Ketamine Plus Usual Care75
Usual Care80

Health Status as Assessed by the Euro-QOL EQ-5D-3L Questionnaire (Current Health)

"For this item of the Euro-QOL EQ-5D-3L questionnaire, participants are asked the question How would you rate your health today?, and they respond with a score from 0 - 100, with a higher score indicating a better outcome." (NCT04129086)
Timeframe: Hospital discharge (about 1 to 6 weeks after admission)

Interventionscore on a scale (Median)
Ketamine Plus Usual Care70
Usual Care75

Health Status as Assessed by the Euro-QOL EQ-5D-3L Questionnaire (Previous Experience)

"For this item of the Euro-QOL EQ-5D-3L questionnaire, participants are asked the question Have you ever experience this kind of event?, and data are reported as the number of participants who responded yes." (NCT04129086)
Timeframe: 6 months post admission

InterventionParticipants (Count of Participants)
Ketamine Plus Usual Care69
Usual Care78

Health Status as Assessed by the Euro-QOL EQ-5D-3L Questionnaire (Previous Experience)

"For this item of the Euro-QOL EQ-5D-3L questionnaire, participants are asked the question Have you ever experience this kind of event?, and data are reported as the number of participants who responded yes." (NCT04129086)
Timeframe: Hospital discharge (about 1 to 6 weeks after admission)

InterventionParticipants (Count of Participants)
Ketamine Plus Usual Care82
Usual Care77

Hospital Free Days

Number of days patients were not in the hospital during the first 30 days after admission (NCT04129086)
Timeframe: 30 days post admission

Interventiondays (Median)
Ketamine Plus Usual Care20
Usual Care21

ICU Free Days

Number of inpatient hospital days patients did not require ICU level of care (NCT04129086)
Timeframe: Hospital discharge (up to 6 weeks post hospital admission)

Interventiondays (Median)
Ketamine Plus Usual Care29
Usual Care28

Number of Patients Requesting to Discontinue Ketamine

Number of patients requesting to stop Ketamine for any complaint (NCT04129086)
Timeframe: Hospital discharge (up to 6 weeks post hospital admission)

InterventionParticipants (Count of Participants)
Ketamine Plus Usual Care9
Usual Care0

Number of Patients That Required Unplanned Intubation During In-hospital Stay

incidence of need for unplanned intubation during in-hospital stay (NCT04129086)
Timeframe: Hospital discharge (up to 6 weeks post hospital admission)

InterventionParticipants (Count of Participants)
Ketamine Plus Usual Care2
Usual Care3

Number of Patients That Showed Signs of Delirium During In-hospital Stay

Incidence of delirium during in-hospital stay (NCT04129086)
Timeframe: Hospital discharge (up to 6 weeks post hospital admission)

InterventionParticipants (Count of Participants)
Ketamine Plus Usual Care16
Usual Care9

Number of Patients Who Continue to Use Opioids at 6 Months Post Admission

Number of patients who continue to use opioids (NCT04129086)
Timeframe: 6 months post admission

InterventionParticipants (Count of Participants)
Ketamine Plus Usual Care11
Usual Care11

Number of Patients Who Reported Continued Pain Continued Post-traumatic Pain at 6 Months Post Admission

Number of patients who reported continued pain at 6 months following trauma injury (NCT04129086)
Timeframe: 6 months post admission

InterventionParticipants (Count of Participants)
Ketamine Plus Usual Care78
Usual Care71

Number of Patients Who Required Unplanned Admission to Intensive Care Unit During In-hospital Stay

Incidence of need for unplanned admission to an ICU (NCT04129086)
Timeframe: Hospital discharge (up to 6 weeks post hospital admission)

InterventionParticipants (Count of Participants)
Ketamine Plus Usual Care7
Usual Care7

Pain as Assessed by Average Score on the Defense and Veterans Pain Rating Scale (DVPRS)

DVPRS scores were collected daily. For each participant, an average of the daily scores on the Defense and Veterans Pain Rating Scale was calculated. DVPRS scores range from 0 (no pain) to 10 (as bad as it could be, nothing else matters), with a higher score indicating a worse outcome. (NCT04129086)
Timeframe: From time of admission to time of discharge from hospital (about 1 to 6 weeks after admission)

Interventionscore on a scale (Median)
Ketamine Plus Usual Care2.9
Usual Care2.5

Ventilator Free Days

Number of inpatient hospital days patients did not require mechanical ventilation (NCT04129086)
Timeframe: Hospital discharge (up to 6 weeks post hospital admission)

Interventiondays (Median)
Ketamine Plus Usual Care30
Usual Care30

Health Status as Assessed by the Euro-QOL EQ-5D-3L Questionnaire (Anxiety/Depression)

For this item of the Euro-QOL EQ-5D-3L questionnaire, participants are asked to indicate their level of anxiety/depression by choosing a predefined category, and the data for this outcome are reported categorically as the number of participants who chose each category. (NCT04129086)
Timeframe: 6 months post admission

,
InterventionParticipants (Count of Participants)
I am not anxious or depressedI am slightly anxious or depressedI am moderately anxious or depressedI am severely anxious or depressedI am extremely anxious or depressed
Ketamine Plus Usual Care501511418
Usual Care531913215

Health Status as Assessed by the Euro-QOL EQ-5D-3L Questionnaire (Anxiety/Depression)

For this item of the Euro-QOL EQ-5D-3L questionnaire, participants are asked to indicate their level of anxiety/depression by choosing a predefined category, and the data for this outcome are reported categorically as the number of participants who chose each category. (NCT04129086)
Timeframe: Hospital discharge (about 1 to 6 weeks after admission)

,
InterventionParticipants (Count of Participants)
I am not anxious or depressedI am slightly anxious or depressedI am moderately anxious or depressedI am severely anxious or depressedI am extremely anxious or depressed
Ketamine Plus Usual Care702411613
Usual Care742015713

Health Status as Assessed by the Euro-QOL EQ-5D-3L Questionnaire (Mobility)

For this item of the Euro-QOL EQ-5D-3L questionnaire, participants are asked to indicate their level of mobility by choosing a predefined category, and the data for this outcome are reported categorically as the number of participants who chose each category. (NCT04129086)
Timeframe: 6 months post admission

,
InterventionParticipants (Count of Participants)
I have no problems walkingI have slight problems walkingI have moderate problems walkingI have severe problems walkingI am unable to walk
Ketamine Plus Usual Care501512914
Usual Care47211789

Health Status as Assessed by the Euro-QOL EQ-5D-3L Questionnaire (Mobility)

For this item of the Euro-QOL EQ-5D-3L questionnaire, participants are asked to indicate their level of mobility by choosing a predefined category, and the data for this outcome are reported categorically as the number of participants who chose each category. (NCT04129086)
Timeframe: Hospital discharge (about 1 to 6 weeks after admission)

,
InterventionParticipants (Count of Participants)
I have no problems walkingI have slight problems walkingI have moderate problems walkingI have severe problems walkingI am unable to walk
Ketamine Plus Usual Care3922151335
Usual Care3120131748

Health Status as Assessed by the Euro-QOL EQ-5D-3L Questionnaire (Pain/Discomfort)

For this item of the Euro-QOL EQ-5D-3L questionnaire, participants are asked to indicate their level of pain/discomfort by choosing a predefined category, and the data for this outcome are reported categorically as the number of participants who chose each category. (NCT04129086)
Timeframe: 6 months post admission

,
InterventionParticipants (Count of Participants)
I have no pain or discomfortI have slight pain or discomfortI have moderate pain or discomfortI have severe pain or discomfortI have extreme pain or discomfort
Ketamine Plus Usual Care3117211021
Usual Care2521241814

Health Status as Assessed by the Euro-QOL EQ-5D-3L Questionnaire (Pain/Discomfort)

For this item of the Euro-QOL EQ-5D-3L questionnaire, participants are asked to indicate their level of pain/discomfort by choosing a predefined category, and the data for this outcome are reported categorically as the number of participants who chose each category. (NCT04129086)
Timeframe: Hospital discharge (about 1 to 6 weeks after admission)

,
InterventionParticipants (Count of Participants)
I have no pain or discomfortI have slight pain or discomfortI have moderate pain or discomfortI have severe pain or discomfortI have extreme pain or discomfort
Ketamine Plus Usual Care2534302114
Usual Care1632391824

Health Status as Assessed by the Euro-QOL EQ-5D-3L Questionnaire (Self-Care)

For this item of the Euro-QOL EQ-5D-3L questionnaire, participants are asked to indicate their level of mobility by choosing a predefined category, and the data for this outcome are reported categorically as the number of participants who chose each category. (NCT04129086)
Timeframe: 6 months post admission

,
InterventionParticipants (Count of Participants)
I have no problems washing or dressing myselfI have slight problems washing or dressing myselfI have moderate problems washing or dressing myselfI have severe problems washing or dressing myselfI am unable to wash or dress myself
Ketamine Plus Usual Care291216934
Usual Care3810141128

Health Status as Assessed by the Euro-QOL EQ-5D-3L Questionnaire (Self-Care)

For this item of the Euro-QOL EQ-5D-3L questionnaire, participants are asked to indicate their level of self-care by choosing a predefined category, and the data for this outcome are reported categorically as the number of participants who chose each category. (NCT04129086)
Timeframe: Hospital discharge (about 1 to 6 weeks after admission)

,
InterventionParticipants (Count of Participants)
I have no problems washing or dressing myselfI have slight problems washing or dressing myselfI have moderate problems washing or dressing myselfI have severe problems washing or dressing myselfI am unable to wash or dress myself
Ketamine Plus Usual Care422413540
Usual Care371915751

Health Status as Assessed by the Euro-QOL EQ-5D-3L Questionnaire (Usual Activities)

For this item of the Euro-QOL EQ-5D-3L questionnaire, participants are asked to indicate their ability to carry out usual activities by choosing a predefined category, and the data for this outcome are reported categorically as the number of participants who chose each category. (NCT04129086)
Timeframe: 6 months post admission

,
InterventionParticipants (Count of Participants)
I have no problems doing my usual activitiesI have slight problems doing my usual activitiesI have moderate problems doing my usual activitiesI have severe problems doing my usual activitiesI am unable to do my usual activities
Ketamine Plus Usual Care291216934
Usual Care3810141128

Health Status as Assessed by the Euro-QOL EQ-5D-3L Questionnaire (Usual Activities)

For this item of the Euro-QOL EQ-5D-3L questionnaire, participants are asked to indicate their ability to carry out usual activities by choosing a predefined category, and the data for this outcome are reported categorically as the number of participants who chose each category. (NCT04129086)
Timeframe: Hospital discharge (about 1 to 6 weeks after admission)

,
InterventionParticipants (Count of Participants)
I have no problems doing my usual activitiesI have slight problems doing my usual activitiesI have moderate problems doing my usual activitiesI have severe problems doing my usual activitiesI am unable to do my usual activities
Ketamine Plus Usual Care1785292
Usual Care7109499

Number of Patients Discharged From the Hospital With an Opioid Prescription

Number of patients discharged from the hospital with an opioid prescription (NCT04129086)
Timeframe: Hospital discharge (up to 6 weeks post hospital admission)

,
InterventionParticipants (Count of Participants)
Any Opioid at dischargeTramadolHydrocodoneOxycodoneCodeineMethadoneFentanyl patchHydromorphoneMorphine
Ketamine Plus Usual Care827231010001
Usual Care978121530000

Post Traumatic Stress Disorder (PTSD) as Assessed by the PC-PTSD-5 Questionnaire

"The PC-PTSD-5 questionnaire asks the below 5 questions, and data are reported categorically as the number of participants who responded yes to each of the 5 questions. An answer of yes is indicative of a PTSD symptom, which is a worse outcome.~In the past month, have you had nightmares about the events or thought about the events when you did not want to?~In the past month, have you tried hard not to think about the events or went out of your way to avoid situations that reminded you of the events?~In the past month, have you been constantly on guard, watchful, or easily startled?~In the past month, have you felt numb or detached from people, activities, or your surroundings?~In the past month, have you felt guilty or unable to stop blaming yourself or others for the events or any problems the events may have caused?" (NCT04129086)
Timeframe: 6 months post admission

,
InterventionParticipants (Count of Participants)
1. had nightmares about the events or thought about the events when you did not want to2. tried hard not to think about the events or went out of your way to avoid situations3. been constantly on guard, watchful, or easily startled4. felt numb or detached from people, activities, or your surrounding5. felt guilty or unable to stop blaming yourself or others
Ketamine Plus Usual Care2441423724
Usual Care1944473623

Post Traumatic Stress Disorder (PTSD) as Assessed by the PC-PTSD-5 Questionnaire

"The PC-PTSD-5 questionnaire asks the below 5 questions, and data are reported categorically as the number of participants who responded yes to each of the 5 questions. An answer of yes is indicative of a PTSD symptom, which is a worse outcome.~In the past month, have you had nightmares about the events or thought about the events when you did not want to?~In the past month, have you tried hard not to think about the events or went out of your way to avoid situations that reminded you of the events?~In the past month, have you been constantly on guard, watchful, or easily startled?~In the past month, have you felt numb or detached from people, activities, or your surroundings?~In the past month, have you felt guilty or unable to stop blaming yourself or others for the events or any problems the events may have caused?" (NCT04129086)
Timeframe: Hospital discharge (about 1 to 6 weeks after admission)

,
InterventionParticipants (Count of Participants)
1. had nightmares about the events or thought about the events when you did not want to2. tried hard not to think about the events or went out of your way to avoid situations3. been constantly on guard, watchful, or easily startled4. felt numb or detached from people, activities, or your surrounding5. felt guilty or unable to stop blaming yourself or others
Ketamine Plus Usual Care3035362419
Usual Care1849433125

Risk of Future Opioid Abuse as Assessed by the Opioid Risk Tool (ORT)

Total ORT score ranges from 0 to 26. A score of 3 or lower indicates low risk for future opioid abuse, a score of 4 to 7 indicates moderate risk for opioid abuse, and a score of 8 or higher indicates a high risk for opioid abuse. (NCT04129086)
Timeframe: Hospital discharge (about 1 to 6 weeks after admission)

,
InterventionParticipants (Count of Participants)
Low risk of future opioid abuse (score of 0-3)Moderate risk of future opioid abuse (score of 4-7)High risk of future opioid abuse (score of 8 or higher)
Ketamine Plus Usual Care921319
Usual Care942510

Use of Other Pain Control Adjuncts Including Regional Anesthesia and Lidocaine Patch

Incidence of use of additional pain control adjuncts such as regional anesthesia and lidocaine patch during hospitalization (NCT04129086)
Timeframe: Hospital discharge (up to 6 weeks post hospital admission)

,
InterventionParticipants (Count of Participants)
Regional anesthesiaLidocaine drip
Ketamine Plus Usual Care160
Usual Care200

Adverse Events

"Frequency of adverse events secondary to ketamine including fatigue, dizziness, nausea, headache, feeling of unreality, changes in hearing or vision, mood changes, generalized discomfort, and hallucinations, changes in vital signs.~Adverse events were reported at baseline and then at 15 min/30 min/60 min/90 min and 120 minutes post-infusion." (NCT03896230)
Timeframe: Within 2 hours post infusion completion

,,
Interventionparticipants (Number)
at 15 min post infusionat 30 min post infusionat 60 min post infusionat 90 min post infusionat 120 min post infusion
Arm 1: 0.1 mg/kg Ketamine21111
Arm 1: 0.2 mg/kg Ketamine32220
Arm 1: 0.3 mg/kg Ketamine21000

Pain Score

"Pain score using Numerical Rating Scale (NRS) post ketamine infusion. The Numerical Rating Scale (NRS) ranges from 0-to-10 with 0 being no pain and lower numbers representing less pain, so in this case lower numbers will represent better outcomes.~Pain scores were reported at baseline and then at 15 min/30 min/60 min/90 min and 120 minutes post-infusion." (NCT03896230)
Timeframe: Within 2 hours post infusion completion

,
Interventionscore on a scale (Mean)
Baseline pain scorePain score at 15 minPain score at 30 minPain score at 60 minPain score at 90 min
Arm 1: 0.3 mg/kg Ketamine7.52652
Arm 1: 0.2 mg/kg Ketamine8.565.7577

Pain Score

"Pain score using Numerical Rating Scale (NRS) post ketamine infusion. The Numerical Rating Scale (NRS) ranges from 0-to-10 with 0 being no pain and lower numbers representing less pain, so in this case lower numbers will represent better outcomes.~Pain scores were reported at baseline and then at 15 min/30 min/60 min/90 min and 120 minutes post-infusion." (NCT03896230)
Timeframe: Within 2 hours post infusion completion

Interventionscore on a scale (Mean)
Baseline pain scorePain score at 15 minPain score at 30 minPain score at 60 minPain score at 90 minPain score at 120 min
Arm 1: 0.1 mg/kg Ketamine9.45.255.255.254.54

Breakthrough Daily Opioid Requirement

Breakthrough daily opioid requirement in milligrams of morphine equivalents/day (NCT02062879)
Timeframe: Participants will be followed for their entire hospital stay, an expected average of 1 week

Interventionmg morphine equivalents/day (Median)
Ketamine10
Hydromorphone10

Median Pain Score

Median daily pain score measures on a visual analogue scale for pain, with a range of 0 to 10. Higher scored indicate worse pain. (NCT02062879)
Timeframe: Participants will be followed for their entire hospital stay, an expected average of 1 week

Interventionscores on a scale (Median)
Ketamine6.3
Hydromorphone5.3

Total Daily Opioid Requirement

Daily breakthrough opioid requirement plus non-breakthrough opioid use in milligrams of morphine equivalents (NCT02062879)
Timeframe: Participants will be followed for their entire hospital stay, an expected average of 1 week.

Interventionmg morphine equivalents/day (Median)
Ketamine10
Hydromorphone42.5

Incidence of Side Effects, Including Outlying Vital Signs

The patient will be assessed for vital signs (blood pressure, heart rate, respiratory rate, oxygen saturation), Ramsay Sedation Scale (RSS) score at 5,10,20 minutes following medication administration and then every 20 minutes until a total of 120 minutes from the first dose of study medication. outlying vital signs recorded.( systolic Blood pressure less than 90mmHg or greater than 150mmHg, Heart rate less than 50bpm or greater than 150bpm, oxygen saturation below 90%, respiratory rate below 9breaths/minute or greater than 40breaths/minute and RSS of 1 or greater than 3) The RSS was used to asses the level of agitation or sedation caused by the intervention .the scale ranges from 1(anxious/agitated) to 6( no response to stimulus-deep sedation) with 2 being the optimal (cooperative, oriented and tranquil).A checklist for side effects like airway problems, allergic reactions, salivation, dysphoria,nystagmus, respiratory/cardiac arrest, awakening hallucinations, nausea/vomiting was used (NCT02434939)
Timeframe: 5, 10, 20, 40, 60, 80, 100, 120 minutes post drug administration

Interventionparticipants (Number)
Low Dose Ketamine45
Morphine4

Incidence of Treatment Failure by Treatment Group.

Requiring more than two doses of the study medication provided for adequate pain control (NCT02434939)
Timeframe: 120 minutes

Interventionparticipants (Number)
Low Dose Ketamine34
Morphine48

Maximal Change in NRS Pain Scores as a Percentage of Baseline NRS Pain Score.

Our primary outcome measurement was the maximum change on the verbal NRS pain scale compared with their initial score (baseline). The NRS was used to measure a patient's subjective level of pain on a scale from 0 (representing no pain at all) to 10 (the worst pain imaginable) using whole numbers. The NRS score was documented just prior to the administration of the study drug (time zero). After infusion of the study drug was complete, NRS scores were documented at 5, 10, 20, and then every 20 minutes thereafter up to 120 minutes. We stopped recording NRS scores prior to 120 minutes if the patient requested a third dose of the study drug, withdrew consent or developed a severe adverse effect. (NCT02434939)
Timeframe: 5, 10, 20,25,30, 40,45,50 60, 80, 100, 120 minutes post drug adminstration

,
Interventionpercent change from baseline NRS score. (Mean)
OverallExcluding Treatment failuresAmong Treatment failuresThose still at maximal effect at 120
Low Dose Ketamine-66.4-81.1-33.8-80
Morphine-61.3-79.8-33.9-81.7

Time to Maximal Analgesic Effect and Duration of Action of Ketamine

"Following dosage with study medication, the amount of time taken to demonstrate the maximal change in the patient's NRS pain score.~Maximal change in NRS pain score is to be defined as the largest change from patient's baseline pain score. Duration of maximal change is how long the patient's pain score remained at this level." (NCT02434939)
Timeframe: 5, 10, 20, 40, 60, 80, 100, 120 minutes post drug administration

,
Interventionminutes (Mean)
time to maximal effectduration of maximal effect
Low Dose Ketamine19.860
Morphine34.158.5

Reduction of Pain Score at 30 Minutes

The primary outcome will be the comparative reduction of NRS pain scores between the 2 groups at 30 minutes. The NRS Pain scale ranges from 0 to 10 (0 being no pain at all to 10 being very severe pain; 5 is moderate pain) (NCT02673372)
Timeframe: 30 minutes

Interventionscore on a scale (Mean)
Morphine Group4.4
Ketamine Group4.2

Hallucination

Hallucinations were documented and confirmed by the treating medical team. (NCT02432456)
Timeframe: Total Index Hospitalization up to 365 days

,
InterventionParticipants (Count of Participants)
AdultElderly
Ketamine Infusion02
Placebo Infusion12

Length of Stay

Total hospital length of stay in days up to 365 days. (NCT02432456)
Timeframe: Total Index Hospitalization up to 365 days

,
Interventiondays (Median)
AdultElderly
Ketamine Infusion55
Placebo Infusion4.06

Oral Morphine Equivalent (Narcotic Usage)

This is an analysis of the narcotic utilization during the study. Oral Morphine Equivalents is a means of standardizing narcotic utilization given a multitude of different medications are utilized. Medications are standardized to units (milligrams) or oral morphine for a standardized comparison. (NCT02432456)
Timeframe: 12-24 hours post infusion

,
Interventionoral morphine equivalents (Median)
AdultElderly
Ketamine Infusion4521.3
Placebo Infusion45.030

Oral Morphine Equivalent (Narcotic Usage)

This is an analysis of the narcotic utilization during the study. Oral Morphine Equivalents is a means of standardizing narcotic utilization given a multitude of different medications are utilized. Medications are standardized to units (milligrams) or oral morphine for a standardized comparison. (NCT02432456)
Timeframe: 24-48 hours post infusion

,
Interventionoral morphine equivalents (Median)
AdultElderly
Ketamine Infusion69.025
Placebo Infusion6744

Oral Morphine Equivalent (Narcotic Usage) in Severely Injured

This is an analysis of the narcotic utilization during the study. Oral Morphine Equivalents is a means of standardizing narcotic utilization given a multitude of different medications are utilized. Medications are standardized to units (milligrams) or oral morphine for a standardized comparison. (NCT02432456)
Timeframe: Total Index Hospitalization up to 365 days

,
Interventionoral morphine equivalents (Median)
AdultElderly
Ketamine Infusion153.067.5
Placebo Infusion170.586.8

Regional Anesthesia Utilization

This is a measure of the Epidural Placement rates. Epidural placement was binary as in patient received or did not receive an epidural infusion catheter for supplemental pain management. (NCT02432456)
Timeframe: Total Index Hospitalization up to 365 days

,
Interventionparticipants (Number)
AdultElderly
Ketamine Infusion74
Placebo Infusion36

Respiratory Failure

Respiratory failure within this trial was defined by the need for unanticipated intubation and/or transfer to ICU for respiratory support. (NCT02432456)
Timeframe: Total Index Hospitalization up to 365 days

,
InterventionParticipants (Count of Participants)
AdultElderly
Ketamine Infusion20
Placebo Infusion30

Visual Analog Numeric Pain Score

Visual Analog Numeric Pain scores are reported as a single numeric score between 0 and 10. The more severe the pain the higher the number with 10 representing the most severe pain imaginable. (NCT02432456)
Timeframe: 12-24 hours post infusion

,
Interventionscore on a scale (Mean)
AdultElderly
Ketamine Infusion5.75.1
Placebo Infusion6.15.2

Visual Analog Numeric Pain Score

Visual Analog Numeric Pain scores are reported as a single numeric score between 0 and 10. The more severe the pain the higher the number with 10 representing the most severe pain imaginable. (NCT02432456)
Timeframe: 24-48 hours post infusion

,
Interventionscore on a scale (Mean)
AdultElderly
Ketamine Infusion5.65.1
Placebo Infusion5.84.4

Change From Baseline of Pain as Described by Numeric Rating Scale (NRS) [Minimum:0, Maximum 10] at 15 Minutes

Change from Baseline of Pain as described by Numeric Rating Scale (NRS) [minimum:0, maximum 10] at 15 minutes. Lower values indicate worst outcomes while higher values indicate better outcomes. (NCT02306759)
Timeframe: 15 minutes after administration of study intervention

Interventionunits on a scale (Median)
Treatment3.5
Placebo6.0

ED Length of Stay (Minutes)

ED Length of stay (minutes) throughout study period (NCT02306759)
Timeframe: throughout study completion

Interventionminutes (Mean)
Treatment267
Placebo292

Number of Participants With Adverse Events

Incidence or number of participants with adverse events. (NCT02306759)
Timeframe: during the study period

Interventionparticipants (Number)
Treatment2
Placebo4

Patient Satisfaction of Pain Control Based on a Likert Scale

Patient satisfaction of pain control based on a Likert Scale at the end of study completion, an average of 90 minutes. Scores reported out of scale of 10, 10 being most satisfied and 1 being least satisfied. (NCT02306759)
Timeframe: At the end of study period

Interventionunits on a scale (Mean)
Treatment8.57
Placebo6.05

Mean Consumption of Rescue Analgesia

(NCT02306759)
Timeframe: at designated intervals during study period (0, 15, 30, 45, 60, 75, 90, 105, 120 minutes)

,
Interventionmilligrams (Mean)
T5T15T30T45T60T75T90T105T120
Placebo00.140.2800.22000.420.42
Treatment00.230.370.07000.480.550

Number of Participants With an Adverse Effects

We will monitor for adverse effects and record for changes in vital signs including nausea and vomiting, hypotension, respiratory depression, laryngospasm, and emotional and psychological effects (emergence reactions). (NCT02430818)
Timeframe: 60 minutes

Interventionparticipants (Number)
Ketamine1
Morphine1

Pain Treatment-VAS (Visual Analog Scale)

Study outcomes involve change in participants' pain as measured by a visual analog scale. The scale is a 10 inch line from 0 to 10 inches with 10 being the most pain and 0 being no pain. There are no units on the scale; it is just a straight line from no pain (0) to the worst pain (10). We assessed at o, 15, and 60 minutes but only scored the VAS at 60 minutes. (NCT02430818)
Timeframe: At 0 minutes and 60 minutes

Interventionscore on a scale (Median)
Ketamine4
Morphine4

Would the Participant Would Consider Using the Drug Given to Them for Pain Relief in the Future

Patients will be assessed to determine whether the participant would consider using the drug given to them for pain relief in the future. It was measured on a likert scale from 1-5 with 1 being did not like and would not use the drug again to 5 being like and would definitely receive the medication again. There are no units. The numbers below are the total number of patients that completed this answer. This was only asked on patients that received medication as if they did not receive medication the answer would not make sense. The median value is the likert value on a scale of 1-5 with the standard deviation. (NCT02430818)
Timeframe: 60 minutes

Interventionunits on a scale (Median)
Ketamine4
Morphine4

Change in Level of Pain Control as Reported on the NRS-11

"Patient-reported pain scores on numerical rating scale (NRS) -11 pain scale (where 0 indicates no pain at all, 10 indicates the most severe pain). Initial group were patients enrolled and randomized in to the study, assessments were taken at the time of enrollment/randomization in to the study (up to 20 min prior to T=0). T = 0 min assessments were conducted at the time of medication administration (study allowed for an up to 20-minute delay in receiving study drug in order to retrieve study drug from secure storage, nursing documentation and patient verification prior to administration)." (NCT02489630)
Timeframe: 20 min pre-medication administration, 0 min, 30 min, 60 min, 90 min, 120 min post medication administration

,
InterventionUnits on a scale (1-10) (Mean)
InitialT = 0 minT = 30 minT = 60 minT = 90 minT = 120 min
Ketamine9.387.515.255.314.514.24
Placebo9.448.102.276.186.215.68

Change in Patient Satisfaction With Pain Control on a 1-4 Likert Scale

Patient-reported score regarding satisfaction with pain control, reported on a 4-point Likert scale (1-4, where 1 is the lowest satisfaction score possible and 4 is the highest satisfaction score possible). No data is reported for T = 0 min, as that assessment was conducted concurrently with initial medication dosing (since patients were at that point receiving their first pain control efforts, they could not yet assess their satisfaction with those efforts). (NCT02489630)
Timeframe: 0 min, 30 min, 60 min, 90 min, 120 min post medication administration

,
InterventionUnits on a scale (1-4) (Mean)
T = 30 minT = 60 minT = 90 minT = 120 min
Ketamine2.092.382.542.66
Placebo2.272.332.382.52

Difference in Opiate Dosage Between Study Arms in Morphine Equivalents

"Average difference in opiate dosage between study arms, calculated in morphine equivalents. Initial indicates at first dose of opioid administration, up to 20 mins prior to study drug administration, and from 0 min to 120 min after study drug administration." (NCT02489630)
Timeframe: 20 mins pre-medication administration, 0 min, 30 min, 60 min, 90 min, 120 min post medication administration

,
InterventionMilligrams of Morphine Equivalent (Mean)
Initial Narcotic DosageTotal Narcotic Dosage
Ketamine5.419.95
Placebo5.8312.81

Effect of Low-dose Ketamine (LDK) on Opioid Usage in the ED

Opioid usage for at least one but up to three prior patient visits in the last one year for each patient enrolled in the study was summarized, expressed as morphine equivalents in mg/kg/h, to account for different types of opioids used per patient preference, and then this was compared to the intervention group that received LDK. Percent change in opioid usage (expressed as morphine equivalents in mg/kg/h) is reported). (NCT03296345)
Timeframe: Up to one year prior and after LDK administration on day 1 of the study in the ED

Interventionpercent change (Mean)
Intervention-15

Effect of Low-dose Ketamine on Discharge Rates From the ED

"Percent discharge from the ED for intervention group and for at least one but up to three visits prior to receipt of ketamine in the last one year, were assessed. Participants were assigned a 0 if discharged or 1 if not discharged." (NCT03296345)
Timeframe: Up to one year prior to receipt of ketamine for the historical control arm/group and up to 18 months for the intervention arm/group

Interventionpercentage of participants (Number)
Intervention33
Historical Control17

Effect of Low-dose Ketamine on Pain Scores on Presentation to the ED

Patient pain scores at presentation for the enrolled encounters and for at least one but up to three visits prior to receipt of ketamine in the last one year, were assessed. At least one but up to three prior visits were averaged and compared to the intervention visit. Pain was assessed using the faces pain scale which consists of a series of line diagrams of faces with expressions of increasing distress. The score ranges from 0 (no pain) to 10 (the worst pain). (NCT03296345)
Timeframe: Up to one year prior and on presentation to the ED after LDK administration

InterventionScore on a scale (Mean)
Intervention9.23
Historical Control9.08

Effect of Low-dose Ketamine on Patient Pain Scores on Discharge From the ED/Admission to the Hospital

Patient pain scores at time of discharge from the ED/admission to the hospital for at least one but up to three visits prior to receipt of ketamine in the last one year, were assessed. At least one but up to three prior visits were averaged and compared to the intervention visit. Pain scores post receipt of ketamine are presented for the intervention group. Pain was assessed using the faces pain scale which consists of a series of line diagrams of faces with expressions of increasing distress. The score ranges from 0 (no pain) to 10 (the worst pain). (NCT03296345)
Timeframe: At time of discharge from the ED/admission to the hospital (up to one year prior and after LDK administration)

InterventionScore on a scale (Mean)
Intervention7.15
Historical Control7.26

Effect of Low-dose Ketamine on Percent Difference of Length of Stay (LOS) in the ED

Length of stay (LOS) in minutes in the ED for at least one but up to three visits prior to receipt of ketamine in the last one year, were assessed. (NCT03296345)
Timeframe: Up to one year prior to and after LDK administration on day 1 of the study in the ED

InterventionLOS in minutes (Mean)
Intervention273.5
Historical Control217.3

Effect of Low-dose Ketamine on Time to 50% Pain Reduction

Time to 50% pain reduction (pain reported 50% less than baseline) in minutes for at least one but up to three visits prior to receipt of ketamine in the last one year, were assessed as historical controls. Pain was assessed using the faces pain scale which consists of a series of line diagrams of faces with expressions of increasing distress. The score ranges from 0 (no pain) to 10 (the worst pain). (NCT03296345)
Timeframe: Up to one year prior to and after LDK administration on day 1 of the study in the ED

Interventiontime to 50% pain reduction in minutes (Mean)
Intervention116.1
Historical Control167.3

Subjective Effect of Low Dose Ketamine on Pain Relief Assessed Via a Patient Survey

"After receipt of LDK, patients and/or their parents, based on age, filled out a survey based on a Likert scale regarding their agreement (Strongly Disagree to Strongly Agree) with the following statements: Achieved faster pain relief with LDK, Achieved more complete pain relief with LDK, and Desire to receive LDK in a future vaso-occlusive crisis. There is also an area where patients could provide general comments regarding their experience in receiving LDK.~Count of Participants who agree or strongly agree for each question are reported." (NCT03296345)
Timeframe: after LDK administration on day 1 of the study in the ED

InterventionParticipants (Count of Participants)
Achieved faster pain relief?Achieved more complete pain relief?Desire to receive LDK in the future?
Intervention433049

ASES

American Shoulder and Elbow Surgeons (ASES) Shoulder Score for pain and function. Range 0-100. Low score = worse shoulder condition. Function, disability, and pain subscores (all ranges 0-50), and are summed for total ASES score. (NCT03540030)
Timeframe: 2 Weeks

Interventionunits on a scale (Median)
Observational54.3
Non-Opioid Intervention54.2

Morphine Use

Morphine milli-equivalents In-hospital post-operative. Continuous scale of MME, no defined better/worse. Measured as number and dose of medications taken. For example, if the patient received an opioid, the drug and dose was recorded and converted to MME. A time frame of when to assess opioid use in-hospital post-operative was not used but was a continuous monitor for rescue opioid from in-hospital post-operative through discharge. (NCT03540030)
Timeframe: In-hospital Stay

InterventionMorphine milli-equivalents (Median)
Observational45.0
Non-Opioid Intervention19.0

Post Op Pain

Pain at patient discharge or 24-hours, whichever comes first - measured on a 0 (no pain) -10 (worst possible pain) numeric rating scale (NRS). A score of 0(no pain) is preferable to 10(worst possible pain) (NCT03540030)
Timeframe: 24 hours

Interventionscore on a scale (Median)
Observational3.0
Non-Opioid Intervention2.0

Simple Shoulder Test

Simple Shoulder Test (SST) activity score. Range 0-12. 0 = worse activity score. (NCT03540030)
Timeframe: 2 Months

Interventionscore on a scale (Median)
Observational6
Non-Opioid Intervention6

Simple Shoulder Test

Simple Shoulder Test (SST) activity score. Range 0-12. 0 = worse activity score. (NCT03540030)
Timeframe: 2 Weeks

Interventionscore on a scale (Median)
Observational2.0
Non-Opioid Intervention2.0

Additional Post Op Pain

post-operative pain: measured on a 0 (no pain) -10 (worst) numeric rating scale (NRS) at 6hrs, 12hrs, 2 weeks, and 2 months. A score of 0(no pain) is preferable to 10(worst possible pain) (NCT03540030)
Timeframe: 6hrs, 12hrs, 2weeks, 2 months

,
Interventionscore on a scale (Median)
6 Hrs12 hrs2 weeks2 months
Non-Opioid Intervention0.000.820
Observational241.30.7

Constipation

rate of constipation (NCT03540030)
Timeframe: 2 Months

,
InterventionParticipants (Count of Participants)
YesNoUnknown
Non-Opioid Intervention4274
Observational7212

Constipation

rate of constipation (NCT03540030)
Timeframe: 2 Weeks

,
InterventionParticipants (Count of Participants)
YesNoUnknown
Non-Opioid Intervention13220
Observational1992

Falls

rate of falls (NCT03540030)
Timeframe: 2 Months

,
InterventionParticipants (Count of Participants)
YesNoUnknown
Non-Opioid Intervention4274
Observational4242

Falls

rate of falls (NCT03540030)
Timeframe: 2 Weeks

,
InterventionParticipants (Count of Participants)
YesNoUnknown
Non-Opioid Intervention5300
Observational1272

Nausea

rate of nausea (NCT03540030)
Timeframe: 2 Months

,
InterventionParticipants (Count of Participants)
YesNoUnknown
Non-Opioid Intervention1300
Observational0282

Nausea

rate of nausea (NCT03540030)
Timeframe: 2 Weeks

,
InterventionParticipants (Count of Participants)
YesNoUnknown
Non-Opioid Intervention1340
Observational5232

Pain Satisfaction

Satisfaction with overall pain using Numeric Pain Rating (NRS) scale. yes, no. No being better than yes. (NCT03540030)
Timeframe: 2 Months

,
InterventionParticipants (Count of Participants)
YesNoUnknown
Non-Opioid Intervention2924
Observational2352

Pain Satisfaction

Satisfaction with overall pain using Numeric Pain Rating (NRS) scale. yes, no. No being better than yes. (NCT03540030)
Timeframe: 2 Weeks

,
InterventionParticipants (Count of Participants)
YesNoUnknown
Non-Opioid Intervention3410
Observational2712

Veterans RAND 12 Item Health Survey (VR-12©) Physical Health Subscore, and Mental Health Subscore

quality of life using VR-12 subscores. Physical Health (PCS) subscore and Mental Health (MCS) subscore, not summed. Range reported in weighted units. Physical Health subscore: 1 point increase in PCS is associated with 6% lower total health care expenditures, 5% lower pharmacy expenditures, 9% lower rate of hospital inpatient visits, 4% lower rate of medical provider visits, 5% lower rate of hospital outpatient visits. Mental Health sub score a 1 point increase in MCS is associated with 7% lower total health care expenditures, 4% lower pharmacy expenditures, 15% lower rate of hospital inpatient visits, and 4% lower rate of medical provider visits. Both PCS/MCS are score 0-100 with 100 indicating the highest level of health. (NCT03540030)
Timeframe: 2 Months

,
Interventionscore on a scale (Median)
PCSMCS
Non-Opioid Intervention40.360.8
Observational38.458.7

Veterans RAND 12 Item Health Survey (VR-12©) Physical Health Subscore, and Mental Health Subscore

quality of life using VR-12 subscores. Physical Health (PCS) subscore and Mental Health (MCS) subscore, not summed. Range reported in weighted units. Physical Health subscore: 1 point increase in PCS is associated with 6% lower total health care expenditures, 5% lower pharmacy expenditures, 9% lower rate of hospital inpatient visits, 4% lower rate of medical provider visits, 5% lower rate of hospital outpatient visits. Mental Health sub score a 1 point increase in MCS is associated with 7% lower total health care expenditures, 4% lower pharmacy expenditures, 15% lower rate of hospital inpatient visits, and 4% lower rate of medical provider visits. Both PCS/MCS are score 0-100 with 100 indicating the highest level of health. (NCT03540030)
Timeframe: 2 Weeks

,
Interventionscore on a scale (Median)
PCSMCS
Non-Opioid Intervention35.059.1
Observational36.756.3

Anxiety

Reduction in 100 mm Visual Analog Scale (VAS) Score. The maximum possible change in VAS score is 100 mm, representing the complete relief of maximum anxiety. A change of 0 mm corresponds to no change in anxiety level, and a negative value indicates worsening of the anxiety after the medication. (NCT02657031)
Timeframe: 0-60 minutes

Interventionmm (Mean)
Control Arm33.7
Study Arm21.2

Headache Following Intervention

Reduction in 100 mm Visual Analog Scale (VAS) Score. Positive values represent a reduction in headache severity. The maximum possible change in VAS score is 100 mm, representing the complete relief of a maximally severe headache. A change of 0 mm corresponds to no change in headache severity, and a negative value indicates worsening of the headache after the medication. (NCT02657031)
Timeframe: 0-60 minutes

Interventionmm (Mean)
Control Arm63.5
Study Arm43.5

Nausea

Reduction in 100 mm Visual Analog Scale (VAS) Score. The maximum possible change in VAS score is 100 mm, representing the complete relief of maximum nausea. A change of 0 mm corresponds to no change in nausea level, and a negative value indicates worsening of the nausea after the medication. (NCT02657031)
Timeframe: 0-60 minutes

Interventionmm (Mean)
Control Arm38.9
Study Arm22.9

The Number of Participants Experiencing Vomiting

Yes/No (NCT02657031)
Timeframe: 0-60 minutes

Interventionparticipants (Number)
Control Arm2
Study Arm3

The Number of Patients Experiencing Restlessness

Yes/No (NCT02657031)
Timeframe: 0-60 minutes

Interventionparticipants (Number)
Control Arm3
Study Arm3

Reviews

28 reviews available for ketamine and Acute Pain

ArticleYear
Perioperative ketamine for postoperative pain management in patients with preoperative opioid intake: A systematic review and meta-analysis.
    Journal of clinical anesthesia, 2022, Volume: 78

    Topics: Acute Pain; Adult; Analgesics, Opioid; Humans; Hyperalgesia; Ketamine; Pain, Postoperative

2022
The Effectiveness of Ketamine Compared to Opioid Analgesics for management of acute pain in Children in The Emergency Department: systematic Review.
    The American journal of emergency medicine, 2022, Volume: 61

    Topics: Acute Pain; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Fentanyl; Humans; Ke

2022
Subanaesthetic single-dose ketamine as an adjunct to opioid analgesics for acute pain management in the emergency department: a systematic review and meta-analysis.
    BMJ open, 2023, 03-27, Volume: 13, Issue:3

    Topics: Acute Pain; Adult; Analgesics, Opioid; Emergency Service, Hospital; Humans; Ketamine; Pain Managemen

2023
Efficacy of Low-dose Ketamine for Control of Acute Pain in the Emergency Setting: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
    The western journal of emergency medicine, 2023, May-09, Volume: 24, Issue:3

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Child; Humans; Ketamine; Randomized Controlled Tr

2023
[Ketamine for medically-delegated analgesia in the Emergency Department].
    Revue medicale suisse, 2023, Oct-04, Volume: 19, Issue:844

    Topics: Acute Pain; Analgesia; Analgesics; Emergency Service, Hospital; Humans; Ketamine; Pain Management

2023
Intranasal Ketamine for Treatment of Acute Pain in Pediatrics: A Systematic Review.
    Pediatric emergency care, 2020, Volume: 36, Issue:8

    Topics: Acute Pain; Administration, Intranasal; Analgesics; Child; Humans; Ketamine

2020
Intranasal ketamine for acute pain management in children: A systematic review and meta-analysis.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:9

    Topics: Acute Pain; Administration, Intranasal; Analgesics; Child; Fentanyl; Humans; Ketamine; Pain Manageme

2020
Low-dose Ketamine For Acute Pain Control in the Emergency Department: A Systematic Review and Meta-analysis.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2021, Volume: 28, Issue:4

    Topics: Acute Pain; Analgesics; Emergency Service, Hospital; Humans; Ketamine; Pain Management

2021
The Effect of Ketamine on Acute and Chronic Wound Pain in Patients Undergoing Breast Surgery: A Meta-Analysis and Systematic Review.
    Pain practice : the official journal of World Institute of Pain, 2021, Volume: 21, Issue:3

    Topics: Acute Pain; Analgesics; Analgesics, Opioid; Breast Neoplasms; Bupivacaine; Chronic Pain; Female; Hum

2021
Ketamine for the treatment of prehospital acute pain: a systematic review of benefit and harm.
    BMJ open, 2020, 11-24, Volume: 10, Issue:11

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Emergency Medical Services; Humans; Ketamine; Ran

2020
Intranasal Ketamine for Acute Pain.
    The Clinical journal of pain, 2021, 04-01, Volume: 37, Issue:4

    Topics: Acute Pain; Administration, Intranasal; Analgesics; Analgesics, Opioid; Child; Double-Blind Method;

2021
Efficacy of intranasal ketamine for acute pain management in adults: a systematic review and meta-analysis.
    European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:8

    Topics: Acute Pain; Administration, Intranasal; Analgesics; Humans; Ketamine; Pain Management; Pain Measurem

2021
Systematic review of the use of low-dose ketamine for analgesia in the emergency department.
    CJEM, 2018, Volume: 20, Issue:1

    Topics: Acute Pain; Analgesia; Analgesics; Dose-Response Relationship, Drug; Emergency Service, Hospital; Hu

2018
Ketamine in the treatment of acute pain.
    Duodecim; laaketieteellinen aikakauskirja, 2017, Volume: 133, Issue:9

    Topics: Acute Pain; Anesthetics, Dissociative; Humans; Ketamine; Pain Management

2017
A Systematic Review and Meta-analysis of Ketamine as an Alternative to Opioids for Acute Pain in the Emergency Department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2018, Volume: 25, Issue:10

    Topics: Acute Pain; Administration, Intravenous; Adult; Analgesics, Opioid; Anesthetics, Dissociative; Emerg

2018
A Systematic Review and Meta-analysis of Ketamine as an Alternative to Opioids for Acute Pain in the Emergency Department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2018, Volume: 25, Issue:10

    Topics: Acute Pain; Administration, Intravenous; Adult; Analgesics, Opioid; Anesthetics, Dissociative; Emerg

2018
A Systematic Review and Meta-analysis of Ketamine as an Alternative to Opioids for Acute Pain in the Emergency Department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2018, Volume: 25, Issue:10

    Topics: Acute Pain; Administration, Intravenous; Adult; Analgesics, Opioid; Anesthetics, Dissociative; Emerg

2018
A Systematic Review and Meta-analysis of Ketamine as an Alternative to Opioids for Acute Pain in the Emergency Department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2018, Volume: 25, Issue:10

    Topics: Acute Pain; Administration, Intravenous; Adult; Analgesics, Opioid; Anesthetics, Dissociative; Emerg

2018
Hot Off the Press: A Systematic Review And Meta-analysis of Ketamine as an Alternative to Opioids for Acute Pain in the Emergency Department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2019, Volume: 26, Issue:8

    Topics: Acute Pain; Administration, Intravenous; Adult; Analgesics; Analgesics, Opioid; Emergency Service, H

2019
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
Perioperative intravenous ketamine for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2018, 12-20, Volume: 12

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg

2018
NMDA receptor antagonists and pain relief: A meta-analysis of experimental trials.
    Neurology, 2019, 04-02, Volume: 92, Issue:14

    Topics: Acute Pain; Dextromethorphan; Excitatory Amino Acid Antagonists; Humans; Hyperalgesia; Ketamine; Mod

2019
Chronic pain after childbirth.
    International journal of obstetric anesthesia, 2013, Volume: 22, Issue:2

    Topics: Acute Pain; Adrenergic alpha-Agonists; Adult; Amines; Analgesics; Anesthetics, Dissociative; Cesarea

2013
Postoperative pain management after total knee arthroplasty in elderly patients: treatment options.
    Drugs & aging, 2014, Volume: 31, Issue:2

    Topics: Acetaminophen; Acute Pain; Aged; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anti-Inflam

2014
Postoperative pain management after total knee arthroplasty in elderly patients: treatment options.
    Drugs & aging, 2014, Volume: 31, Issue:2

    Topics: Acetaminophen; Acute Pain; Aged; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anti-Inflam

2014
Postoperative pain management after total knee arthroplasty in elderly patients: treatment options.
    Drugs & aging, 2014, Volume: 31, Issue:2

    Topics: Acetaminophen; Acute Pain; Aged; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anti-Inflam

2014
Postoperative pain management after total knee arthroplasty in elderly patients: treatment options.
    Drugs & aging, 2014, Volume: 31, Issue:2

    Topics: Acetaminophen; Acute Pain; Aged; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anti-Inflam

2014
Postoperative pain management after total knee arthroplasty in elderly patients: treatment options.
    Drugs & aging, 2014, Volume: 31, Issue:2

    Topics: Acetaminophen; Acute Pain; Aged; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anti-Inflam

2014
Postoperative pain management after total knee arthroplasty in elderly patients: treatment options.
    Drugs & aging, 2014, Volume: 31, Issue:2

    Topics: Acetaminophen; Acute Pain; Aged; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anti-Inflam

2014
Postoperative pain management after total knee arthroplasty in elderly patients: treatment options.
    Drugs & aging, 2014, Volume: 31, Issue:2

    Topics: Acetaminophen; Acute Pain; Aged; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anti-Inflam

2014
Postoperative pain management after total knee arthroplasty in elderly patients: treatment options.
    Drugs & aging, 2014, Volume: 31, Issue:2

    Topics: Acetaminophen; Acute Pain; Aged; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anti-Inflam

2014
Postoperative pain management after total knee arthroplasty in elderly patients: treatment options.
    Drugs & aging, 2014, Volume: 31, Issue:2

    Topics: Acetaminophen; Acute Pain; Aged; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anti-Inflam

2014
The use of subdissociative-dose ketamine for acute pain in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2015, Volume: 22, Issue:3

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Female; Fenta

2015
The use of subdissociative-dose ketamine for acute pain in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2015, Volume: 22, Issue:3

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Female; Fenta

2015
The use of subdissociative-dose ketamine for acute pain in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2015, Volume: 22, Issue:3

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Female; Fenta

2015
The use of subdissociative-dose ketamine for acute pain in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2015, Volume: 22, Issue:3

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Female; Fenta

2015
The use of subdissociative-dose ketamine for acute pain in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2015, Volume: 22, Issue:3

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Female; Fenta

2015
The use of subdissociative-dose ketamine for acute pain in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2015, Volume: 22, Issue:3

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Female; Fenta

2015
The use of subdissociative-dose ketamine for acute pain in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2015, Volume: 22, Issue:3

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Female; Fenta

2015
The use of subdissociative-dose ketamine for acute pain in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2015, Volume: 22, Issue:3

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Female; Fenta

2015
The use of subdissociative-dose ketamine for acute pain in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2015, Volume: 22, Issue:3

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Female; Fenta

2015
Role of ketamine in acute postoperative pain management: a narrative review.
    BioMed research international, 2015, Volume: 2015

    Topics: Acute Pain; Anesthetics, Dissociative; Dose-Response Relationship, Drug; Evidence-Based Medicine; Hu

2015
Role of ketamine in acute postoperative pain management: a narrative review.
    BioMed research international, 2015, Volume: 2015

    Topics: Acute Pain; Anesthetics, Dissociative; Dose-Response Relationship, Drug; Evidence-Based Medicine; Hu

2015
Role of ketamine in acute postoperative pain management: a narrative review.
    BioMed research international, 2015, Volume: 2015

    Topics: Acute Pain; Anesthetics, Dissociative; Dose-Response Relationship, Drug; Evidence-Based Medicine; Hu

2015
Role of ketamine in acute postoperative pain management: a narrative review.
    BioMed research international, 2015, Volume: 2015

    Topics: Acute Pain; Anesthetics, Dissociative; Dose-Response Relationship, Drug; Evidence-Based Medicine; Hu

2015
Ketamine added to morphine or hydromorphone patient-controlled analgesia for acute postoperative pain in adults: a systematic review and meta-analysis of randomized trials.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2016, Volume: 63, Issue:3

    Topics: Acute Pain; Adult; Analgesia, Patient-Controlled; Drug Combinations; Humans; Hydromorphone; Ketamine

2016
Advanced Concepts and Controversies in Emergency Department Pain Management.
    Anesthesiology clinics, 2016, Volume: 34, Issue:2

    Topics: Acetaminophen; Acute Pain; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agen

2016
Can Chronic Pain Be Prevented?
    Anesthesiology clinics, 2016, Volume: 34, Issue:2

    Topics: Acute Pain; Amines; Anesthesia, Conduction; Chronic Pain; Cyclohexanecarboxylic Acids; Epigenesis, G

2016
Is There a Role for Intravenous Subdissociative-Dose Ketamine Administered as an Adjunct to Opioids or as a Single Agent for Acute Pain Management in the Emergency Department?
    The Journal of emergency medicine, 2016, Volume: 51, Issue:6

    Topics: Acute Pain; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Dissociative; Drug Therapy

2016
Is There a Role for Intravenous Subdissociative-Dose Ketamine Administered as an Adjunct to Opioids or as a Single Agent for Acute Pain Management in the Emergency Department?
    The Journal of emergency medicine, 2016, Volume: 51, Issue:6

    Topics: Acute Pain; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Dissociative; Drug Therapy

2016
Is There a Role for Intravenous Subdissociative-Dose Ketamine Administered as an Adjunct to Opioids or as a Single Agent for Acute Pain Management in the Emergency Department?
    The Journal of emergency medicine, 2016, Volume: 51, Issue:6

    Topics: Acute Pain; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Dissociative; Drug Therapy

2016
Is There a Role for Intravenous Subdissociative-Dose Ketamine Administered as an Adjunct to Opioids or as a Single Agent for Acute Pain Management in the Emergency Department?
    The Journal of emergency medicine, 2016, Volume: 51, Issue:6

    Topics: Acute Pain; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Dissociative; Drug Therapy

2016
The Effects of Low-Dose Ketamine on Acute Pain in an Emergency Setting: A Systematic Review and Meta-Analysis.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Acute Pain; Dose-Response Relationship, Drug; Emergency Medical Services; Humans; Ketamine; Treatmen

2016
The Effects of Low-Dose Ketamine on Acute Pain in an Emergency Setting: A Systematic Review and Meta-Analysis.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Acute Pain; Dose-Response Relationship, Drug; Emergency Medical Services; Humans; Ketamine; Treatmen

2016
The Effects of Low-Dose Ketamine on Acute Pain in an Emergency Setting: A Systematic Review and Meta-Analysis.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Acute Pain; Dose-Response Relationship, Drug; Emergency Medical Services; Humans; Ketamine; Treatmen

2016
The Effects of Low-Dose Ketamine on Acute Pain in an Emergency Setting: A Systematic Review and Meta-Analysis.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Acute Pain; Dose-Response Relationship, Drug; Emergency Medical Services; Humans; Ketamine; Treatmen

2016
BET 2: Low-dose ketamine for acute pain in the ED.
    Emergency medicine journal : EMJ, 2016, Volume: 33, Issue:12

    Topics: Acute Pain; Analgesics; Analgesics, Opioid; Emergency Service, Hospital; Evidence-Based Emergency Me

2016

Trials

31 trials available for ketamine and Acute Pain

ArticleYear
Sub dissociative dose of ketamine with haloperidol versus fentanyl on pain reduction in patients with acute pain in the emergency department; a randomized clinical trial.
    The American journal of emergency medicine, 2022, Volume: 54

    Topics: Acute Pain; Adult; Analgesics; Double-Blind Method; Emergency Service, Hospital; Fentanyl; Haloperid

2022
Non-inferiority of intranasal ketamine compared to intravenous morphine for musculoskeletal pain relief among older adults in an emergency department: a randomised controlled trial.
    Age and ageing, 2022, 03-01, Volume: 51, Issue:3

    Topics: Acute Pain; Aged; Analgesics; Analgesics, Opioid; Double-Blind Method; Emergency Service, Hospital;

2022
Oral Aspirin/ketamine versus oral ketamine for emergency department patients with acute musculoskeletal pain.
    The American journal of emergency medicine, 2022, Volume: 58

    Topics: Acute Pain; Adult; Analgesics; Aspirin; Double-Blind Method; Emergency Service, Hospital; Humans; Ke

2022
Evaluation of the effect of perioperative administration of S(+)-ketamine hydrochloride injection for postoperative acute pain in children: study protocol for a prospective, multicenter, randomized, open-label, parallel-group, pragmatic clinical trial.
    Trials, 2022, Jul-23, Volume: 23, Issue:1

    Topics: Acute Pain; Adolescent; Analgesics; Analgesics, Opioid; Child; Child, Preschool; Humans; Infant; Inf

2022
Ketamine for acute pain after trauma: the KAPT randomized controlled trial.
    Trials, 2022, Jul-27, Volume: 23, Issue:1

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Humans; Ketamine; Pain Measurement; Pain, Postope

2022
Ultrasound-guided selective peripheral nerve block compared with the sub-dissociative dose of ketamine for analgesia in patients with extremity injuries.
    The American journal of emergency medicine, 2023, Volume: 63

    Topics: Acute Pain; Humans; Ketamine; Peripheral Nerves; Plastic Surgery Procedures; Prospective Studies

2023
Randomised controlled trial of analgesia for the management of acute severe pain from traumatic injury: study protocol for the paramedic analgesia comparing ketamine and morphine in trauma (PACKMaN).
    Scandinavian journal of trauma, resuscitation and emergency medicine, 2023, Nov-24, Volume: 31, Issue:1

    Topics: Acute Pain; Adolescent; Analgesia; Analgesics, Opioid; Double-Blind Method; Humans; Ketamine; Morphi

2023
Ketamine infusion for pain control in elderly patients with multiple rib fractures: Results of a randomized controlled trial.
    The journal of trauma and acute care surgery, 2019, Volume: 87, Issue:5

    Topics: Acute Pain; Age Factors; Aged; Aged, 80 and over; Analgesics; Dose-Response Relationship, Drug; Doub

2019
Effect on Opioids Requirement of Early Administration of Intranasal Ketamine for Acute Traumatic Pain.
    The Clinical journal of pain, 2020, Volume: 36, Issue:6

    Topics: Acute Pain; Analgesics; Analgesics, Opioid; Double-Blind Method; Humans; Ketamine; Prospective Studi

2020
A randomized, noninferiority, controlled trial of two doses of intravenous subdissociative ketamine for analgesia in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2021, Volume: 28, Issue:6

    Topics: Acute Pain; Adolescent; Adult; Analgesia; Analgesics, Opioid; Double-Blind Method; Emergency Service

2021
Topical ketamine as a local anesthetic agent in reducing venipuncture pain: A randomized controlled trial.
    The American journal of emergency medicine, 2021, Volume: 48

    Topics: Acute Pain; Administration, Cutaneous; Adolescent; Adult; Anesthesia, Local; Anesthetics, Local; Dou

2021
Comparison of Nebulized Ketamine at Three Different Dosing Regimens for Treating Painful Conditions in the Emergency Department: A Prospective, Randomized, Double-Blind Clinical Trial.
    Annals of emergency medicine, 2021, Volume: 78, Issue:6

    Topics: Acute Pain; Administration, Intravenous; Adult; Aged; Analgesics; Double-Blind Method; Emergency Ser

2021
Efficacy and Tolerability of Oral Compared with Sublingual Ketamine Lozenges as Rescue Analgesics in Adults for Acute Pain: The OSKet Trial.
    Clinical drug investigation, 2021, Volume: 41, Issue:9

    Topics: Acute Pain; Administration, Sublingual; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method;

2021
Ketamine administration for acute painful sickle cell crisis: A randomized controlled trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2022, Volume: 29, Issue:2

    Topics: Acute Pain; Analgesics; Analgesics, Opioid; Anemia, Sickle Cell; Double-Blind Method; Humans; Ketami

2022
Can low-dose of ketamine reduce the need for morphine in renal colic? A double-blind randomized clinical trial.
    The American journal of emergency medicine, 2018, Volume: 36, Issue:3

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Therapy, Combination; E

2018
Can low-dose of ketamine reduce the need for morphine in renal colic? A double-blind randomized clinical trial.
    The American journal of emergency medicine, 2018, Volume: 36, Issue:3

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Therapy, Combination; E

2018
Can low-dose of ketamine reduce the need for morphine in renal colic? A double-blind randomized clinical trial.
    The American journal of emergency medicine, 2018, Volume: 36, Issue:3

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Therapy, Combination; E

2018
Can low-dose of ketamine reduce the need for morphine in renal colic? A double-blind randomized clinical trial.
    The American journal of emergency medicine, 2018, Volume: 36, Issue:3

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Therapy, Combination; E

2018
Randomized Controlled Feasibility Trial of Intranasal Ketamine Compared to Intranasal Fentanyl for Analgesia in Children with Suspected Extremity Fractures.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2017, Volume: 24, Issue:12

    Topics: Acute Pain; Administration, Intranasal; Adolescent; Analgesics; Arm Injuries; Child; Child, Preschoo

2017
Ketamine versus hydromorphone patient-controlled analgesia for acute pain in trauma patients.
    The Journal of surgical research, 2018, Volume: 225

    Topics: Acute Pain; Adult; Analgesia, Patient-Controlled; Analgesics; Double-Blind Method; Female; Hallucina

2018
Is intravenously administered, subdissociative-dose KETAmine non-inferior to MORPHine for prehospital analgesia (the KETAMORPH study): study protocol for a randomized controlled trial.
    Trials, 2018, May-02, Volume: 19, Issue:1

    Topics: Acute Pain; Administration, Intravenous; Analgesics, Opioid; Anesthetics, Dissociative; Emergency Me

2018
Low dose ketamine versus morphine for acute severe vaso occlusive pain in children: a randomized controlled trial.
    Scandinavian journal of pain, 2018, 01-26, Volume: 18, Issue:1

    Topics: Acute Pain; Administration, Intravenous; Adolescent; Analgesics; Anemia, Sickle Cell; Child; Double-

2018
Low dose ketamine versus morphine for acute severe vaso occlusive pain in children: a randomized controlled trial.
    Scandinavian journal of pain, 2018, 01-26, Volume: 18, Issue:1

    Topics: Acute Pain; Administration, Intravenous; Adolescent; Analgesics; Anemia, Sickle Cell; Child; Double-

2018
Low dose ketamine versus morphine for acute severe vaso occlusive pain in children: a randomized controlled trial.
    Scandinavian journal of pain, 2018, 01-26, Volume: 18, Issue:1

    Topics: Acute Pain; Administration, Intravenous; Adolescent; Analgesics; Anemia, Sickle Cell; Child; Double-

2018
Low dose ketamine versus morphine for acute severe vaso occlusive pain in children: a randomized controlled trial.
    Scandinavian journal of pain, 2018, 01-26, Volume: 18, Issue:1

    Topics: Acute Pain; Administration, Intravenous; Adolescent; Analgesics; Anemia, Sickle Cell; Child; Double-

2018
Intravenous subdissociative-dose ketamine versus morphine for acute geriatric pain in the Emergency Department: A randomized controlled trial.
    The American journal of emergency medicine, 2019, Volume: 37, Issue:2

    Topics: Acute Pain; Aged; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Eme

2019
Intravenous subdissociative-dose ketamine versus morphine for acute geriatric pain in the Emergency Department: A randomized controlled trial.
    The American journal of emergency medicine, 2019, Volume: 37, Issue:2

    Topics: Acute Pain; Aged; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Eme

2019
Intravenous subdissociative-dose ketamine versus morphine for acute geriatric pain in the Emergency Department: A randomized controlled trial.
    The American journal of emergency medicine, 2019, Volume: 37, Issue:2

    Topics: Acute Pain; Aged; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Eme

2019
Intravenous subdissociative-dose ketamine versus morphine for acute geriatric pain in the Emergency Department: A randomized controlled trial.
    The American journal of emergency medicine, 2019, Volume: 37, Issue:2

    Topics: Acute Pain; Aged; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Eme

2019
Ketamine infusion for pain control in adult patients with multiple rib fractures: Results of a randomized control trial.
    The journal of trauma and acute care surgery, 2019, Volume: 86, Issue:2

    Topics: Acute Pain; Adolescent; Adult; Aged; Anesthetics, Dissociative; Double-Blind Method; Female; Humans;

2019
Ketamine infusion for pain control in adult patients with multiple rib fractures: Results of a randomized control trial.
    The journal of trauma and acute care surgery, 2019, Volume: 86, Issue:2

    Topics: Acute Pain; Adolescent; Adult; Aged; Anesthetics, Dissociative; Double-Blind Method; Female; Humans;

2019
Ketamine infusion for pain control in adult patients with multiple rib fractures: Results of a randomized control trial.
    The journal of trauma and acute care surgery, 2019, Volume: 86, Issue:2

    Topics: Acute Pain; Adolescent; Adult; Aged; Anesthetics, Dissociative; Double-Blind Method; Female; Humans;

2019
Ketamine infusion for pain control in adult patients with multiple rib fractures: Results of a randomized control trial.
    The journal of trauma and acute care surgery, 2019, Volume: 86, Issue:2

    Topics: Acute Pain; Adolescent; Adult; Aged; Anesthetics, Dissociative; Double-Blind Method; Female; Humans;

2019
Ketamine infusion for pain control in adult patients with multiple rib fractures: Results of a randomized control trial.
    The journal of trauma and acute care surgery, 2019, Volume: 86, Issue:2

    Topics: Acute Pain; Adolescent; Adult; Aged; Anesthetics, Dissociative; Double-Blind Method; Female; Humans;

2019
Ketamine infusion for pain control in adult patients with multiple rib fractures: Results of a randomized control trial.
    The journal of trauma and acute care surgery, 2019, Volume: 86, Issue:2

    Topics: Acute Pain; Adolescent; Adult; Aged; Anesthetics, Dissociative; Double-Blind Method; Female; Humans;

2019
Ketamine infusion for pain control in adult patients with multiple rib fractures: Results of a randomized control trial.
    The journal of trauma and acute care surgery, 2019, Volume: 86, Issue:2

    Topics: Acute Pain; Adolescent; Adult; Aged; Anesthetics, Dissociative; Double-Blind Method; Female; Humans;

2019
Ketamine infusion for pain control in adult patients with multiple rib fractures: Results of a randomized control trial.
    The journal of trauma and acute care surgery, 2019, Volume: 86, Issue:2

    Topics: Acute Pain; Adolescent; Adult; Aged; Anesthetics, Dissociative; Double-Blind Method; Female; Humans;

2019
Ketamine infusion for pain control in adult patients with multiple rib fractures: Results of a randomized control trial.
    The journal of trauma and acute care surgery, 2019, Volume: 86, Issue:2

    Topics: Acute Pain; Adolescent; Adult; Aged; Anesthetics, Dissociative; Double-Blind Method; Female; Humans;

2019
Low-dose Ketamine Does Not Improve Migraine in the Emergency Department: A Randomized Placebo-controlled Trial.
    The western journal of emergency medicine, 2018, Volume: 19, Issue:6

    Topics: Acute Pain; Adult; Anesthetics, Dissociative; Double-Blind Method; Emergency Service, Hospital; Fati

2018
Prehospital Analgesia With Intranasal Ketamine (PAIN-K): A Randomized Double-Blind Trial in Adults.
    Annals of emergency medicine, 2019, Volume: 74, Issue:2

    Topics: Acute Pain; Administration, Intranasal; Adult; Aged; Analgesics; Anesthetics, Inhalation; Double-Bli

2019
Prehospital Analgesia With Intranasal Ketamine (PAIN-K): A Randomized Double-Blind Trial in Adults.
    Annals of emergency medicine, 2019, Volume: 74, Issue:2

    Topics: Acute Pain; Administration, Intranasal; Adult; Aged; Analgesics; Anesthetics, Inhalation; Double-Bli

2019
Prehospital Analgesia With Intranasal Ketamine (PAIN-K): A Randomized Double-Blind Trial in Adults.
    Annals of emergency medicine, 2019, Volume: 74, Issue:2

    Topics: Acute Pain; Administration, Intranasal; Adult; Aged; Analgesics; Anesthetics, Inhalation; Double-Bli

2019
Prehospital Analgesia With Intranasal Ketamine (PAIN-K): A Randomized Double-Blind Trial in Adults.
    Annals of emergency medicine, 2019, Volume: 74, Issue:2

    Topics: Acute Pain; Administration, Intranasal; Adult; Aged; Analgesics; Anesthetics, Inhalation; Double-Bli

2019
Study protocol for a randomized, blinded, controlled trial of ketamine for acute painful crisis of sickle cell disease.
    Trials, 2019, May-27, Volume: 20, Issue:1

    Topics: Acute Pain; Anemia, Sickle Cell; Humans; Ketamine; Morphine; Outcome Assessment, Health Care; Prospe

2019
Effective analgesia with low-dose ketamine and reduced dose hydromorphone in ED patients with severe pain.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:5

    Topics: Acute Pain; Adult; Analgesics; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administra

2013
Effective analgesia with low-dose ketamine and reduced dose hydromorphone in ED patients with severe pain.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:5

    Topics: Acute Pain; Adult; Analgesics; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administra

2013
Effective analgesia with low-dose ketamine and reduced dose hydromorphone in ED patients with severe pain.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:5

    Topics: Acute Pain; Adult; Analgesics; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administra

2013
Effective analgesia with low-dose ketamine and reduced dose hydromorphone in ED patients with severe pain.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:5

    Topics: Acute Pain; Adult; Analgesics; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administra

2013
Effective analgesia with low-dose ketamine and reduced dose hydromorphone in ED patients with severe pain.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:5

    Topics: Acute Pain; Adult; Analgesics; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administra

2013
Effective analgesia with low-dose ketamine and reduced dose hydromorphone in ED patients with severe pain.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:5

    Topics: Acute Pain; Adult; Analgesics; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administra

2013
Effective analgesia with low-dose ketamine and reduced dose hydromorphone in ED patients with severe pain.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:5

    Topics: Acute Pain; Adult; Analgesics; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administra

2013
Effective analgesia with low-dose ketamine and reduced dose hydromorphone in ED patients with severe pain.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:5

    Topics: Acute Pain; Adult; Analgesics; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administra

2013
Effective analgesia with low-dose ketamine and reduced dose hydromorphone in ED patients with severe pain.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:5

    Topics: Acute Pain; Adult; Analgesics; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administra

2013
Effective analgesia with low-dose ketamine and reduced dose hydromorphone in ED patients with severe pain.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:5

    Topics: Acute Pain; Adult; Analgesics; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administra

2013
Effective analgesia with low-dose ketamine and reduced dose hydromorphone in ED patients with severe pain.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:5

    Topics: Acute Pain; Adult; Analgesics; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administra

2013
Effective analgesia with low-dose ketamine and reduced dose hydromorphone in ED patients with severe pain.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:5

    Topics: Acute Pain; Adult; Analgesics; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administra

2013
Effective analgesia with low-dose ketamine and reduced dose hydromorphone in ED patients with severe pain.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:5

    Topics: Acute Pain; Adult; Analgesics; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administra

2013
Effective analgesia with low-dose ketamine and reduced dose hydromorphone in ED patients with severe pain.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:5

    Topics: Acute Pain; Adult; Analgesics; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administra

2013
Effective analgesia with low-dose ketamine and reduced dose hydromorphone in ED patients with severe pain.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:5

    Topics: Acute Pain; Adult; Analgesics; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administra

2013
Effective analgesia with low-dose ketamine and reduced dose hydromorphone in ED patients with severe pain.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:5

    Topics: Acute Pain; Adult; Analgesics; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administra

2013
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Acute Pain; Adult; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Doub

2014
Low-dose ketamine vs morphine for acute pain in the ED: a randomized controlled trial.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:3

    Topics: Acute Pain; Adolescent; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Emergency Servic

2015
Low-dose ketamine vs morphine for acute pain in the ED: a randomized controlled trial.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:3

    Topics: Acute Pain; Adolescent; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Emergency Servic

2015
Low-dose ketamine vs morphine for acute pain in the ED: a randomized controlled trial.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:3

    Topics: Acute Pain; Adolescent; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Emergency Servic

2015
Low-dose ketamine vs morphine for acute pain in the ED: a randomized controlled trial.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:3

    Topics: Acute Pain; Adolescent; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Emergency Servic

2015
Low-dose ketamine vs morphine for acute pain in the ED: a randomized controlled trial.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:3

    Topics: Acute Pain; Adolescent; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Emergency Servic

2015
Low-dose ketamine vs morphine for acute pain in the ED: a randomized controlled trial.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:3

    Topics: Acute Pain; Adolescent; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Emergency Servic

2015
Low-dose ketamine vs morphine for acute pain in the ED: a randomized controlled trial.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:3

    Topics: Acute Pain; Adolescent; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Emergency Servic

2015
Low-dose ketamine vs morphine for acute pain in the ED: a randomized controlled trial.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:3

    Topics: Acute Pain; Adolescent; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Emergency Servic

2015
Low-dose ketamine vs morphine for acute pain in the ED: a randomized controlled trial.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:3

    Topics: Acute Pain; Adolescent; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Emergency Servic

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Adult; Analgesia; Analgesics, Opioid; Anesthetics, Dissociative; Double-Blind Method; Em

2015
Ketamine as an Adjunct to Opioids for Acute Pain in the Emergency Department: A Randomized Controlled Trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2017, Volume: 24, Issue:6

    Topics: Acute Pain; Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Drug T

2017
Ketamine as an Adjunct to Opioids for Acute Pain in the Emergency Department: A Randomized Controlled Trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2017, Volume: 24, Issue:6

    Topics: Acute Pain; Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Drug T

2017
Ketamine as an Adjunct to Opioids for Acute Pain in the Emergency Department: A Randomized Controlled Trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2017, Volume: 24, Issue:6

    Topics: Acute Pain; Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Drug T

2017
Ketamine as an Adjunct to Opioids for Acute Pain in the Emergency Department: A Randomized Controlled Trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2017, Volume: 24, Issue:6

    Topics: Acute Pain; Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Drug T

2017
Ketamine as an Adjunct to Opioids for Acute Pain in the Emergency Department: A Randomized Controlled Trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2017, Volume: 24, Issue:6

    Topics: Acute Pain; Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Drug T

2017
Ketamine as an Adjunct to Opioids for Acute Pain in the Emergency Department: A Randomized Controlled Trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2017, Volume: 24, Issue:6

    Topics: Acute Pain; Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Drug T

2017
Ketamine as an Adjunct to Opioids for Acute Pain in the Emergency Department: A Randomized Controlled Trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2017, Volume: 24, Issue:6

    Topics: Acute Pain; Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Drug T

2017
Ketamine as an Adjunct to Opioids for Acute Pain in the Emergency Department: A Randomized Controlled Trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2017, Volume: 24, Issue:6

    Topics: Acute Pain; Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Drug T

2017
Ketamine as an Adjunct to Opioids for Acute Pain in the Emergency Department: A Randomized Controlled Trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2017, Volume: 24, Issue:6

    Topics: Acute Pain; Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Drug T

2017
A prospective randomized, double-dummy trial comparing IV push low dose ketamine to short infusion of low dose ketamine for treatment of  pain in the ED.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:8

    Topics: Acute Pain; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Emergency Serv

2017
A prospective randomized, double-dummy trial comparing IV push low dose ketamine to short infusion of low dose ketamine for treatment of  pain in the ED.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:8

    Topics: Acute Pain; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Emergency Serv

2017
A prospective randomized, double-dummy trial comparing IV push low dose ketamine to short infusion of low dose ketamine for treatment of  pain in the ED.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:8

    Topics: Acute Pain; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Emergency Serv

2017
A prospective randomized, double-dummy trial comparing IV push low dose ketamine to short infusion of low dose ketamine for treatment of  pain in the ED.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:8

    Topics: Acute Pain; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Emergency Serv

2017
Estimation of the contribution of norketamine to ketamine-induced acute pain relief and neurocognitive impairment in healthy volunteers.
    Anesthesiology, 2012, Volume: 117, Issue:2

    Topics: Acute Pain; Adolescent; Adult; Analgesics; Cognition; Hot Temperature; Humans; Ketamine; Male; Memor

2012

Other Studies

37 other studies available for ketamine and Acute Pain

ArticleYear
Ketamine for the treatment of acute pain.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2021, 11-01, Volume: 193, Issue:43

    Topics: Acute Pain; Analgesics; Analgesics, Opioid; Contraindications, Drug; Dose-Response Relationship, Dru

2021
Evidence-Based Guidelines for Prehospital Pain Management: Recommendations.
    Prehospital emergency care, 2023, Volume: 27, Issue:2

    Topics: Acetaminophen; Acute Pain; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal;

2023
Low-dose ketamine infusions reduce opioid use in pediatric and young adult oncology patients.
    Pediatric blood & cancer, 2022, Volume: 69, Issue:9

    Topics: Acute Pain; Analgesics; Analgesics, Opioid; Child; Death; Humans; Infusions, Intravenous; Ketamine;

2022
Compatibility of intravenous acetaminophen with morphine, fentanyl and ketamine in acute pediatric pain setting.
    Paediatric anaesthesia, 2022, Volume: 32, Issue:7

    Topics: Acetaminophen; Acute Pain; Analgesics, Opioid; Child; Double-Blind Method; Fentanyl; Humans; Ketamin

2022
Analgesic Efficacy of Oral Aspirin/Ketamine Combination for Management of Acute Musculoskeletal Pain in the Emergency Department - A Proof of Concept Pilot Study.
    The Journal of emergency medicine, 2022, Volume: 62, Issue:6

    Topics: Acute Pain; Adult; Analgesics; Aspirin; Double-Blind Method; Emergency Service, Hospital; Humans; Ke

2022
Early Initiation of Sub-Anesthetic Ketamine Infusion in Adults with Vaso-Occlusive Crises Is Associated with Greater Reduction in Sickle Cell Pain Intensity: A Single Center's Experience.
    Pain medicine (Malden, Mass.), 2022, 12-01, Volume: 23, Issue:12

    Topics: Acute Pain; Adolescent; Adult; Analgesics, Opioid; Anemia, Sickle Cell; Anesthetics; Humans; Ketamin

2022
Subanesthetic ketamine: the way forward for pain management in sickle cell disease patients?
    Expert review of hematology, 2022, Volume: 15, Issue:10

    Topics: Acute Pain; Analgesics, Non-Narcotic; Analgesics, Opioid; Anemia, Sickle Cell; Chronic Pain; Humans;

2022
Implementing an intravenous ketamine protocol for acute pain in the medical-surgical setting.
    Journal of the American Association of Nurse Practitioners, 2023, Feb-01, Volume: 35, Issue:2

    Topics: Acute Pain; Analgesics; Analgesics, Opioid; Humans; Infusions, Intravenous; Ketamine; Pain Managemen

2023
Intranasal (2R, 6R)-hydroxynorketamine for acute pain: Behavioural and neurophysiological safety analysis in mice.
    Clinical and experimental pharmacology & physiology, 2023, Volume: 50, Issue:2

    Topics: Acute Pain; Analgesics; Animals; Antidepressive Agents; Depression; Ketamine; Mice

2023
Efficacy of analgesic and sub-dissociative dose ketamine for acute pain in the emergency department.
    The American journal of emergency medicine, 2023, Volume: 70

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug-Related Side Effects an

2023
Application of analgesics in emergency services in Germany: a survey of the medical directors.
    BMC emergency medicine, 2023, 09-14, Volume: 23, Issue:1

    Topics: Acetaminophen; Acute Pain; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Butylsco

2023
Effect of Analgesic Low-Dose Ketamine Infusions on the Cardiovascular Response: A Retrospective Analysis.
    Pain physician, 2023, Volume: 26, Issue:5

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Humans; Hypertension; Ketamine; Pain, Postoperati

2023
Efficacy of multimodal analgesic treatment of severe traumatic acute pain in mice pretreated with chronic high dose of buprenorphine inducing mechanical allodynia.
    European journal of pharmacology, 2020, May-15, Volume: 875

    Topics: Acute Pain; Analgesics; Animals; Buprenorphine; Dose-Response Relationship, Drug; Drug Therapy, Comb

2020
Is low-dose ketamine an effective and safe alternative to opioids for treatment of acute pain in the emergency department?
    CJEM, 2020, Volume: 22, Issue:3

    Topics: Acute Pain; Analgesics; Analgesics, Opioid; Emergency Service, Hospital; Humans; Ketamine

2020
Nebulized Ketamine Used for Pain Management of Orthopedic Trauma.
    The Journal of emergency medicine, 2021, Volume: 60, Issue:3

    Topics: Acute Pain; Analgesics; Analgesics, Opioid; Double-Blind Method; Humans; Ketamine; Pain Management

2021
Low-Dose Ketamine Infusion as Adjuvant Therapy during an Acute Pain Crisis in Pediatric Patients.
    Journal of pain & palliative care pharmacotherapy, 2021, Volume: 35, Issue:1

    Topics: Acute Pain; Adolescent; Analgesics; Analgesics, Opioid; Child; Child, Preschool; Humans; Ketamine; P

2021
Oral Ketamine for Acute Pain Management After Amputation Surgery.
    Pain medicine (Malden, Mass.), 2018, 06-01, Volume: 19, Issue:6

    Topics: Acute Pain; Administration, Oral; Amputation, Surgical; Analgesics; Female; Humans; Ketamine; Male;

2018
Safety in Acute Pain Medicine-Pharmacologic Considerations and the Impact of Systems-Based Gaps.
    Pain medicine (Malden, Mass.), 2018, 11-01, Volume: 19, Issue:11

    Topics: Acetaminophen; Acute Pain; Analgesia; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Humans; K

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesics; Anesthesia, Conduction; Anesthesiologists; Consensus; Humans; Infusions, Int

2018
Ketamine has anti-hyperalgesic effects and relieves acute pain, but does not prevent persistent postoperative pain (PPP).
    Scandinavian journal of pain, 2015, 04-01, Volume: 7, Issue:1

    Topics: Acute Pain; Analgesics; Double-Blind Method; Humans; Hyperalgesia; Ketamine; Pain, Postoperative

2015
Low-Dose Ketamine for Acute Pain Management: A Timely Nudge Toward Multimodal Analgesia.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:5

    Topics: Acute Pain; Analgesia; Analgesics; Dose-Response Relationship, Drug; Humans; Ketamine; Opioid-Relate

2018
BET 2: Safety and efficacy of low-dose ketamine versus opioids for acute pain management in the ED.
    Emergency medicine journal : EMJ, 2019, Volume: 36, Issue:2

    Topics: Acute Pain; Analgesics; Analgesics, Opioid; Emergency Service, Hospital; Humans; Ketamine; Pain Mana

2019
Clinical Pharmacology Considerations in Pain Management in Patients with Advanced Kidney Failure.
    Clinical journal of the American Society of Nephrology : CJASN, 2019, 06-07, Volume: 14, Issue:6

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Analgesics, Opioid; Carbamazepine; Chronic Pain

2019
Ketamine and lidocaine infusions decrease opioid consumption during vaso-occlusive crisis in adolescents with sickle cell disease.
    Current opinion in supportive and palliative care, 2019, Volume: 13, Issue:4

    Topics: Acute Pain; Adolescent; Age Factors; Analgesics, Opioid; Anemia, Sickle Cell; Female; Humans; Infusi

2019
Subanesthetic ketamine infusions for the management of pediatric pain in non-critical care settings: An observational analysis.
    Acta anaesthesiologica Scandinavica, 2019, Volume: 63, Issue:9

    Topics: Acute Pain; Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Child; Child, Preschool; Fema

2019
Oral ketamine for sickle cell crisis pain refractory to opioids.
    Journal of pain & palliative care pharmacotherapy, 2013, Volume: 27, Issue:2

    Topics: Activities of Daily Living; Acute Pain; Administration, Oral; Adult; Analgesics; Analgesics, Opioid;

2013
Oral ketamine for sickle cell crisis pain refractory to opioids.
    Journal of pain & palliative care pharmacotherapy, 2013, Volume: 27, Issue:2

    Topics: Activities of Daily Living; Acute Pain; Administration, Oral; Adult; Analgesics; Analgesics, Opioid;

2013
Oral ketamine for sickle cell crisis pain refractory to opioids.
    Journal of pain & palliative care pharmacotherapy, 2013, Volume: 27, Issue:2

    Topics: Activities of Daily Living; Acute Pain; Administration, Oral; Adult; Analgesics; Analgesics, Opioid;

2013
Oral ketamine for sickle cell crisis pain refractory to opioids.
    Journal of pain & palliative care pharmacotherapy, 2013, Volume: 27, Issue:2

    Topics: Activities of Daily Living; Acute Pain; Administration, Oral; Adult; Analgesics; Analgesics, Opioid;

2013
Oral ketamine for sickle cell crisis pain refractory to opioids.
    Journal of pain & palliative care pharmacotherapy, 2013, Volume: 27, Issue:2

    Topics: Activities of Daily Living; Acute Pain; Administration, Oral; Adult; Analgesics; Analgesics, Opioid;

2013
Oral ketamine for sickle cell crisis pain refractory to opioids.
    Journal of pain & palliative care pharmacotherapy, 2013, Volume: 27, Issue:2

    Topics: Activities of Daily Living; Acute Pain; Administration, Oral; Adult; Analgesics; Analgesics, Opioid;

2013
Oral ketamine for sickle cell crisis pain refractory to opioids.
    Journal of pain & palliative care pharmacotherapy, 2013, Volume: 27, Issue:2

    Topics: Activities of Daily Living; Acute Pain; Administration, Oral; Adult; Analgesics; Analgesics, Opioid;

2013
Oral ketamine for sickle cell crisis pain refractory to opioids.
    Journal of pain & palliative care pharmacotherapy, 2013, Volume: 27, Issue:2

    Topics: Activities of Daily Living; Acute Pain; Administration, Oral; Adult; Analgesics; Analgesics, Opioid;

2013
Oral ketamine for sickle cell crisis pain refractory to opioids.
    Journal of pain & palliative care pharmacotherapy, 2013, Volume: 27, Issue:2

    Topics: Activities of Daily Living; Acute Pain; Administration, Oral; Adult; Analgesics; Analgesics, Opioid;

2013
Ketamine for acute-on-chronic pain.
    The Canadian nurse, 2013, Volume: 109, Issue:8

    Topics: Acute Pain; Analgesics; Chronic Pain; Humans; Infusions, Intravenous; Ketamine; Nursing Staff, Hospi

2013
Wilderness Medical Society practice guidelines for the treatment of acute pain in remote environments.
    Wilderness & environmental medicine, 2014, Volume: 25, Issue:1

    Topics: Acute Pain; Administration, Intranasal; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Lo

2014
Prehospital analgesia with ketamine for combat wounds: a case series.
    Journal of special operations medicine : a peer reviewed journal for SOF medical professionals, 2014,Winter, Volume: 14, Issue:4

    Topics: Acute Pain; Amputation, Traumatic; Analgesics; Analgesics, Opioid; Benzodiazepines; Emergency Medica

2014
Short (low-dose) ketamine infusion for managing acute pain in the ED: case-report series.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:4

    Topics: Acute Pain; Adult; Aged; Analgesics; Emergency Service, Hospital; Female; Humans; Infusions, Intrave

2015
The first 500: initial experience with widespread use of low-dose ketamine for acute pain management in the ED.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:2

    Topics: Acute Pain; Adult; Aged; Analgesics; Emergency Service, Hospital; Female; Humans; Ketamine; Male; Mi

2015
Low-Dose Ketamine Infusion for Managing Acute Pain.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:9

    Topics: Acute Pain; Analgesics; Emergency Service, Hospital; Female; Humans; Ketamine; Male; Pain Management

2015
Annals of Emergency Medicine Journal Club. Move Over Morphine: Is Ketamine an Effective and Safe Alternative for Treating Acute Pain?: September 2015 Annals of Emergency Medicine Journal Club.
    Annals of emergency medicine, 2015, Volume: 66, Issue:3

    Topics: Acute Pain; Analgesics; Double-Blind Method; Emergencies; Humans; Ketamine; Morphine; Randomized Con

2015
Journal Club: Ketamine in the Emergency Department.
    Journal of special operations medicine : a peer reviewed journal for SOF medical professionals, 2015,Fall, Volume: 15, Issue:3

    Topics: Acute Pain; Analgesics; Female; Humans; Ketamine; Male; Pain Management

2015
Ketamine for pain management in France, an observational survey.
    Anaesthesia, critical care & pain medicine, 2015, Volume: 34, Issue:6

    Topics: Acute Pain; Aged; Anesthetics, Dissociative; Chronic Pain; Female; France; Health Care Surveys; Huma

2015
Intranasal Analgesia and Sedation in Pediatric Emergency Care-A Prospective Observational Study on the Implementation of an Institutional Protocol in a Tertiary Children's Hospital.
    Pediatric emergency care, 2019, Volume: 35, Issue:2

    Topics: Acute Pain; Administration, Intranasal; Adolescent; Analgesia; Child; Child, Preschool; Conscious Se

2019
Antinociception by metoclopramide, ketamine and their combinations in mice.
    Pharmacological reports : PR, 2012, Volume: 64, Issue:2

    Topics: Acute Pain; Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Syne

2012