ketamine has been researched along with Active Hyperemia in 2 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Moreover, the duration of the reactive hyperemia was shorter in the ketamine than in the pentobarbital group (118+/-47 vs." | 5.31 | Comparison between the effects of pentobarbital or ketamine/nitrous oxide anesthesia on metabolic and endothelial components of coronary reactive hyperemia. ( Pagliaro, P; Penna, C; Rastaldo, R, 2001) |
| " Nonetheless, an adequate dosage and way of administration should be considered and established for human use." | 1.40 | The effect of ketamine on optical and electrical characteristics of spreading depolarizations in gyrencephalic swine cortex. ( Orakcioglu, B; Sakowitz, OW; Sánchez-Porras, R; Santos, E; Schiebel, P; Schöll, M; Stock, C; Unterberg, AW; Zheng, Z, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sánchez-Porras, R | 1 |
| Santos, E | 1 |
| Schöll, M | 1 |
| Stock, C | 1 |
| Zheng, Z | 1 |
| Schiebel, P | 1 |
| Orakcioglu, B | 1 |
| Unterberg, AW | 1 |
| Sakowitz, OW | 1 |
| Rastaldo, R | 1 |
| Penna, C | 1 |
| Pagliaro, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Spreading Depolarization and Ketamine Suppression[NCT02501941] | Phase 1 | 10 participants (Actual) | Interventional | 2015-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for ketamine and Active Hyperemia
| Article | Year |
|---|---|
The effect of ketamine on optical and electrical characteristics of spreading depolarizations in gyrencephalic swine cortex.
Topics: Animals; Cerebral Cortex; Cerebrovascular Circulation; Cortical Spreading Depression; Disease Models | 2014 |
Comparison between the effects of pentobarbital or ketamine/nitrous oxide anesthesia on metabolic and endothelial components of coronary reactive hyperemia.
Topics: Anesthesia; Anesthetics, Combined; Animals; Coronary Circulation; Coronary Vessels; Endothelium, Vas | 2001 |