keratan-sulfate has been researched along with Pneumonia* in 1 studies
1 other study(ies) available for keratan-sulfate and Pneumonia
| Article | Year |
|---|---|
A keratan sulfate disaccharide prevents inflammation and the progression of emphysema in murine models.
Emphysema is a typical component of chronic obstructive pulmonary disease (COPD), a progressive and inflammatory airway disease. However, no effective treatment currently exists. Here, we show that keratan sulfate (KS), one of the major glycosaminoglycans produced in the small airway, decreased in lungs of cigarette smoke-exposed mice. To confirm the protective effect of KS in the small airway, a disaccharide repeating unit of KS designated L4 ([SO Topics: Animals; Bronchoalveolar Lavage Fluid; Dexamethasone; Disaccharides; Disease Models, Animal; Disease Progression; Keratan Sulfate; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Models, Biological; Pancreatic Elastase; Pneumonia; Pulmonary Alveoli; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; RAW 264.7 Cells; Smoking; Sus scrofa | 2017 |