keratan-sulfate and Eye-Diseases

keratan-sulfate has been researched along with Eye-Diseases* in 1 studies

Reviews

1 review(s) available for keratan-sulfate and Eye-Diseases

ArticleYear
The versatile roles of lumican in eye diseases: A review.
    The ocular surface, 2023, Volume: 29

    Lumican is a keratan sulfate proteoglycan that belongs to the small leucine-rich proteoglycan family. Research has lifted the veil on the versatile roles of lumican in the pathogenesis of eye diseases. Lumican has pivotal roles in the maintenance of physiological tissue homogenesis and is often upregulated in pathological conditions, e.g., fibrosis, scar tissue formation in injured tissues, persistent inflammatory responses and immune anomaly, etc. Herein, we will review literature regarding the role of lumican in pathogenesis of inherited congenital and acquired eye diseases, e.g., cornea dystrophy, cataract, glaucoma and chorioretinal diseases, etc.

    Topics: Chondroitin Sulfate Proteoglycans; Cornea; Eye Diseases; Humans; Keratan Sulfate; Lumican; Proteoglycans

2023