kaolinite and Salmonella-Infections--Animal

Treatment and control of acute neonatal diarrhea in calves are outlined and discussed. The difficulty in making a definitive etiological diagnosis makes effective treatment and control also difficult and largely empirical. Physiological events in calves with diarrhea are known, and fluid therapy is directed toward treating dehydration and acidosis. Whether affected calves should receive antibacterial agents orally is an open question. Principles of control of diarrhea in calves are outlined and discussed.

Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; Bicarbonates; Cattle; Cattle Diseases; Colostrum; Dehydration; Diarrhea; Diet; Escherichia coli Infections; Glucose; Glycine; Housing, Animal; Infusions, Parenteral; Kaolin; Phosphates; Potassium Chloride; Reoviridae Infections; Salmonella Infections, Animal; Sodium Chloride

The dependence of the invasive action of Salmonella typhimurium in mice on the aggregation of microbial cells has been studied in vivo, as well as in vitro on explanted intestinal tissue. The aggregation of salmonellae on kaolin grains has been found to lead to an increase in the level of adhesion of salmonellae to the intestinal mucosa of mice in vitro, to the accelerated course of infection in mice and their death and to the increased contamination of the spleen. The data obtained in these experiments age indicative of the possibility of the adverse influence of some sorbents on the course of the infectious process and confirm the concept advanced by the authors on the major importance of the surface concentration of salmonellae on the mucous membrane for the effectiveness of contamination.

Topics: Adsorption; Animals; Bacterial Adhesion; Cells, Cultured; Intestinal Absorption; Intestinal Mucosa; Kaolin; Mice; Microscopy, Electron; Salmonella Infections, Animal; Salmonella typhimurium