kaolinite and Hemorrhagic-Disorders

Twelve Indian patients with pre-eclampsia, 15 with eclampsia and 15 with normal pregnancy in the third trimester were investigated. A systemic bleeding diathesis was encountered in two patients with eclampsia and in none with pre-eclampsia; two patients with pre-eclampsia, however, had excessive uterine haemorrhage. Coagulation studies showed statistically significant prolongation of thrombin time, elevation of serum fibrinogen degradation products (FDP) and hypofibrinogenaemia in patients with pre-eclampsia as well as eclampsia. In patients with eclampsia, significant thrombocytopenia also occurred. Euglobulin lysis time showed no significant change in patients with pre-eclampsia and eclampsia. There was no significant difference in the coagulation profile between patients with eclampsia and pre-eclampsia, except for more hypofibrinogenaemia in the former. The laboratory findings suggest the occurrence of intravascular coagulation in patients with pre-eclampsia and eclampsia.

Topics: Adult; Albuminuria; Blood Coagulation; Blood Coagulation Disorders; Blood Platelets; Eclampsia; Edema; Female; Fibrinogen; Hemorrhagic Disorders; Humans; Hypertension; India; Kaolin; Middle Aged; Phosphatidylethanolamines; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third; Prothrombin Time; Serum Globulins; Thrombocytopenia; Uterine Hemorrhage

Topics: Adenine Nucleotides; Adult; Blood Cell Count; Blood Coagulation Factors; Blood Coagulation Tests; Blood Platelet Disorders; Blood Platelets; Child, Preschool; Clot Retraction; Connective Tissue; Female; Hemorrhagic Disorders; Humans; Kaolin; Microscopy, Electron; Photometry; Platelet Adhesiveness; Prothrombin Time; Thrombin

Topics: Adenosine Diphosphate; Albinism; Blood Coagulation Factors; Blood Platelets; Bone Marrow Cells; Collagen; Epinephrine; Hemorrhagic Disorders; Humans; Inclusion Bodies; Kaolin; Lipoproteins; Macrophages; Microscopy, Electron; Norepinephrine; Organoids; Platelet Adhesiveness

Topics: Blood Coagulation Disorders; Blood Coagulation Tests; Child; Diagnosis; Hemorrhagic Disorders; Humans; Infant; Infant, Newborn; Kaolin; Liver Function Tests; Mass Screening

Topics: Blood Coagulation; Blood Coagulation Disorders; Blood Coagulation Tests; Hemorrhagic Disorders; Humans; Kaolin