kaolinite and Gastrointestinal-Hemorrhage

kaolinite has been researched along with Gastrointestinal-Hemorrhage* in 3 studies

Trials

1 trial(s) available for kaolinite and Gastrointestinal-Hemorrhage

Article	Year
Impaired platelet-connective-tissue reaction in man after aspirin ingestion. Lancet (London, England), 1967, Sep-02, Volume: 2, Issue:7514 Topics: Adenine Nucleotides; Adult; Aspirin; Blood Platelets; Connective Tissue; Gastrointestinal Hemorrhage; Humans; Kaolin; Lactose; Male; Placebos; Prothrombin Time	1967

Other Studies

2 other study(ies) available for kaolinite and Gastrointestinal-Hemorrhage

Article	Year
Surgical application of kaolin-impregnated gauze (Combat Gauze) in severe hemorrhagic gastritis. The American surgeon, 2010, Volume: 76, Issue:7 Topics: Accidents, Traffic; Bandages; Gastritis; Gastrointestinal Hemorrhage; Gastroscopy; Hemostatics; Humans; Kaolin; Male; Young Adult	2010
Differences in the haemorrhagic toxicity of aspirin between rats and mice. Acta pharmacologica et toxicologica, 1985, Volume: 56, Issue:1 Rats and mice were fed a diet containing aspirin at levels of 0, 0.3, 0.6 and 1.2% for 1 and 4 weeks. Haemorrhagic death and/or haemorrhagic anaemia occurred in rats in a dose-dependent manner. Prothrombin and kaolin-activated partial thromboplastin time indices were also decreased depending on the daily doses. However, no conspicuous haemorrhagic signs were found in mice given aspirin. These results suggest marked differences in haemorrhagic effects of aspirin between rats and mice. From results of supplementary experiments with two metabolites of aspirin, salicylic acid and gentisic acid, and from the fact of close relationship between hepatic concentration of salicylic acid and haemorrhagic effects of aspirin, it is inferred that salicylic acid may be a precursor for the active metabolite(s) to cause haemorrhage. The mechanism of species differences of aspirin is discussed. Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Gastrointestinal Hemorrhage; Gentisates; Hydroxybenzoates; Kaolin; Liver; Male; Mice; Mice, Inbred ICR; Organ Size; Partial Thromboplastin Time; Prothrombin Time; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Species Specificity; Time Factors	1985

Article

Year

Surgical application of kaolin-impregnated gauze (Combat Gauze) in severe hemorrhagic gastritis.

The American surgeon, 2010, Volume: 76, Issue:7

Topics: Accidents, Traffic; Bandages; Gastritis; Gastrointestinal Hemorrhage; Gastroscopy; Hemostatics; Humans; Kaolin; Male; Young Adult

2010

Differences in the haemorrhagic toxicity of aspirin between rats and mice.

Acta pharmacologica et toxicologica, 1985, Volume: 56, Issue:1

Rats and mice were fed a diet containing aspirin at levels of 0, 0.3, 0.6 and 1.2% for 1 and 4 weeks. Haemorrhagic death and/or haemorrhagic anaemia occurred in rats in a dose-dependent manner. Prothrombin and kaolin-activated partial thromboplastin time indices were also decreased depending on the daily doses. However, no conspicuous haemorrhagic signs were found in mice given aspirin. These results suggest marked differences in haemorrhagic effects of aspirin between rats and mice. From results of supplementary experiments with two metabolites of aspirin, salicylic acid and gentisic acid, and from the fact of close relationship between hepatic concentration of salicylic acid and haemorrhagic effects of aspirin, it is inferred that salicylic acid may be a precursor for the active metabolite(s) to cause haemorrhage. The mechanism of species differences of aspirin is discussed.

Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Gastrointestinal Hemorrhage; Gentisates; Hydroxybenzoates; Kaolin; Liver; Male; Mice; Mice, Inbred ICR; Organ Size; Partial Thromboplastin Time; Prothrombin Time; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Species Specificity; Time Factors

1985