kaolinite and Bronchitis

Topics: Air Pollutants, Occupational; Aluminum Silicates; Bronchitis; Chronic Disease; Crystallization; Dust; Free Radicals; Humans; Kaolin; Models, Theoretical; Occupational Diseases; Pneumoconiosis; Risk Factors; Silicon Dioxide; Silicosis; Thermodynamics

The authors proved variable clinical and pathogenetic features of disease in workers under long occupational exposure to dust of kaolin and its baking products. Therefore, special experimental studies should cover kaolin and mullite as primary and final product in entire technologic sequence of high-alumina refractories production. Natural refractory clay and mullite dust were administered to rats intratracheally during chronic experiments. Lungs of the rats exposed to mullite dust demonstrated reliable changes of lipid content in 1 month and those of hydroxyproline content--in 3 months. When exposed to intratracheal administration of kaolin and mullite dust, respiratory system develops typical changes--slow development of benign diffuse and sclerotic form of pneumoconiosis that is associated or, more frequently, preceded by chronic dust bronchitis.

Topics: Animals; Bronchitis; Chemical Industry; Chronic Disease; Dust; Humans; Hydroxyproline; Kaolin; Lung; Male; Occupational Diseases; Rats

Topics: Adult; Bronchitis; Dust; Female; Gossypium; Humans; Kallikreins; Kaolin; Kinins; Male; Middle Aged; Occupational Diseases; Prekallikrein

Topics: Bronchitis; Cross-Sectional Studies; Environmental Exposure; Forced Expiratory Volume; Humans; Kaolin; Lung; Lung Diseases; Pneumoconiosis; Silicic Acid

Topics: Adult; Air Pollutants; Air Pollutants, Occupational; Bronchitis; Chronic Disease; Dust; Humans; Kaolin; Middle Aged; Pneumoconiosis; Risk

Topics: Aluminum Silicates; Bronchitis; Humans; Kaolin; Pneumoconiosis