Page last updated: 2024-08-17

kanamycin a and Hearing Loss

kanamycin a has been researched along with Hearing Loss in 72 studies

Research

Studies (72)

Timeframe	Studies, this research(%)	All Research%
pre-1990	31 (43.06)	18.7374
1990's	4 (5.56)	18.2507
2000's	7 (9.72)	29.6817
2010's	22 (30.56)	24.3611
2020's	8 (11.11)	2.80

Authors

Authors	Studies
Jeon, J; Kim, SY; Lee, CH; Lee, SM	1
Chen, Z; Dong, H; Fang, J; Mao, S; Shi, H; Su, K; Wu, H; Xing, Y; Yu, D; Zhang, J	1
Chen, M; Ke, Z; Li, M; Li, Y; Liu, K; Qiao, Y; Shi, X; Wang, Y; Wu, L; Zheng, L	1
Balkissou Adamou, D; Kuaban, C; Pefura-Yone, EW; Poka-Mayap, V	1
Budhathoki, C; Dooley, KE; Dowdy, DW; Farley, JE; Francis, HW; Han, HR; Hong, H	1
Deng, X; Hu, Z	1
Bo, C; Han, Y; Liang, S; Liu, W; Wang, H; Wang, M; Wang, X; Xu, L; Zhang, D; Zhang, Z	1
Dai, X; He, XL; Huang, S; Li, J; Xia, ZF; Xiao, H; Yang, R; Zhang, Y	1
Bermúdez-Muñoz, JM; García-Alcántara, F; Martínez-Vega, R; Milo, M; Murillo-Cuesta, S; Pulido, S; Rivera, T; Varela-Nieto, I	1
Ahmed, S; Akhanda, MW; Banu, S; Ebers, A; Gleason, AT; Heysell, SK; Houpt, ER; Rahman, MT	1
Jung, G; Kim, SY; Koo, JW; Shim, YJ	1
Qiu, J; Qiu, Y; Song, Y; Sun, F; Tian, K; Wang, R; Yue, B; Zha, D; Zhou, K	1
Takasu, K; Tateno, T	1
Deng, X; Hu, Z; Li, X; Liu, Z; Zhou, Y	1
Gao, J; Guo, WW; Han, DY; Li, Z; Sun, AL; Sun, DX; Sun, JH; Wei, XN; Yang, SM; Zhang, XF	1
Bharti, H; Bhushan, B; Chander, R; Gupta, A; Kajal, NC; Ranga, V	1
Abbas, L; Rivolta, MN	1
Leufkens, HG; Mantel-Teeuwisse, AK; Mavhunga, F; Rennie, T; Ruswa, N; Sagwa, EL	1
Chabot, N; Clemo, HR; Corley, SB; Lomber, SG; Meredith, MA	1
Basta, D; Ernst, A; Götze, R; Gröschel, M; Müller, S	1
Adebola, SO; Adedeji, TO; Adefuye, BO; Oladeji, SM; Sogebi, OA	1
Alffenaar, JW; Borjas Howard, JF; Dijkstra, JA; Kosterink, JG; van Altena, R; van der Meer, ME; van der Werf, TS; van Soolingen, D	1
Cediel, R; Contreras, J; Murillo-Cuesta, S; Varela-Nieto, I	1
Camarero, G; García-Alcántara, F; Murillo-Cuesta, S; Rivera, T; Sistiaga, JA; Vacas, E; Varela-Nieto, I	1
Hirose, K; Ransohoff, RM; Sato, E; Shick, HE	1
Agterberg, MJ; de Groot, JC; Grolman, W; Havenith, S; Klis, SF; Sedee, RJ; Versnel, H	1
Hirose, K; Sato, E	1
Chen, J; Chen, Q; Chu, H; Cui, Y; Huang, X; Li, J; Li, Z; Wang, Y; Xiong, H; Zhou, L; Zhou, X	1
Chan, HC; Chung, YW; Jiang, XH; Tang, H; Tsang, LL; Wang, AM; Yu, L; Yu, MK; Zhang, XH; Zhou, Z	1
Lai, CJ; Liu, Q; Tian, J; Wang, TF; Yu, HM; Zhang, ZC; Zhou, XY	1
Ding, DL; Jiang, HY; Liu, H; Salvi, R; Sun, H; Wu, XW	1
Lesniak, W; Schacht, J; Sha, SH; Wang, AM	1
Campbell, K	1
PARTSCH, CJ	2
BONNEVILLE, J; WAYOFF, M	1
BRUNELLE, P	1
LEACH, W	1
FROST, JO	1
BECK, C; KRAHL, P	1
BANGS, J; BANGS, T; STEPHENSON, W; TENGG, NE; YOW, MD	1
BREUNINGER, H	1
CHEW, W	1
SCHINDEL, L	1
TAMARI, I; ZONDEK, B	1
DEGREEF, I	1
HAWKINS, JE	1
KRAHL, P	1
OWADA, K; SHIDA, K; WAKAZAWA, T	1
Doi, K; Kaneda, Y; Kubo, T; Mizuno, S; Morishita, R; Nakamura, T; Oshima, K; Shimamura, M; Tamai, K	1
Jiang, H; Schacht, J; Sha, SH	1
Asoh, S; Kashio, A; Ohta, S; Sakamoto, T; Suzukawa, K; Yamasoba, T	1
Gu, ZP; Ke, XM; Liu, YH; Qin, Y; Xiao, SF	1
Konishi, T; Mori, H	1
Alexander, A; Bryant, GM; Cronin-Schreiber, R; Guth, PS; Norris, CH; Quine, DB	1
Niemierko, J; Rutkowski, B	1
Lietman, PS; Moore, RD; Smith, CR	1
Britten, J; Caplan, E; deJongh, CA; Finley, RS; Fortner, CL; Newman, KA; Schimpff, SC; Wade, JC; Wiernik, PH	1
Bock, GR; Miller, JJ; Moorjani, P; Yates, GK	1
Borg, E; Engström, B	1
Deshpande, G; Faden, H; Grossi, M	1
Chen, ZH; She, WD	1
Basile, AS; Berlin, C; Huang, JM; Skolnick, P; Webster, D; Xie, C	1
Dooling, RJ; Manabe, K; Ryals, BM	1
Alam, SA; Ikeda, K; Katori, Y; Kawase, T; Kikuchi, T; Takasaka, T; Watanabe, K	1
Hawkins, JE; Johnson, LG; Moody, DB; Stebbins, WC	1
Ikonen, S; Janas, M; Pesonen, T; Rahko, T	1
Hashino, E; Sokabe, M	1
Hoffman, DW; Jones, KL; Rybak, LP; Whitworth, CA	1
Uziel, A	1
Bredberg, G; Lindquist, NG; Lyttkens, L; Rask-Anderson, H; Wästerström, SA	1
Kameyama, T; Nabeshima, T; Yamaguchi, K	1

Reviews

2 review(s) available for kanamycin a and Hearing Loss

Article	Year
[UNEXPECTED DRUG EFFECTS: KANAMYCIN]. Medizinische Monatsschrift, 1964, Volume: 18 Topics: Deafness; Drug Hypersensitivity; Hearing Disorders; Hearing Loss; Humans; Kanamycin; Kidney Diseases; Toxicology; Vestibule, Labyrinth	1964
Non-genetic factors affecting hearing development. Acta oto-laryngologica. Supplementum, 1985, Volume: 421 Topics: Adult; Age Factors; Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Cochlea; Deafness; Female; Guinea Pigs; Hearing Loss; Hearing Loss, Noise-Induced; Humans; Hyperbilirubinemia; Hypothyroidism; Infant; Infant, Newborn; Kanamycin; Maternal-Fetal Exchange; Pregnancy; Rats	1985

Trials

2 trial(s) available for kanamycin a and Hearing Loss

Article	Year
Risk factors for the development of auditory toxicity in patients receiving aminoglycosides. The Journal of infectious diseases, 1984, Volume: 149, Issue:1 Topics: Amikacin; Body Temperature; Female; Gentamicins; Hearing Loss; Humans; Kanamycin; Male; Probability; Risk; Sepsis; Statistics as Topic; Time Factors; Tobramycin	1984
Comparison of standard versus pharmacokinetically adjusted amikacin dosing in granulocytopenic cancer patients. Antimicrobial agents and chemotherapy, 1982, Volume: 22, Issue:2 Topics: Agranulocytosis; Amikacin; Bacterial Infections; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Fever; Hearing Loss; Humans; Kanamycin; Kidney; Kinetics; Moxalactam; Neoplasms; Piperacillin; Ticarcillin	1982

Article

Year

Risk factors for the development of auditory toxicity in patients receiving aminoglycosides.

The Journal of infectious diseases, 1984, Volume: 149, Issue:1

Topics: Amikacin; Body Temperature; Female; Gentamicins; Hearing Loss; Humans; Kanamycin; Male; Probability; Risk; Sepsis; Statistics as Topic; Time Factors; Tobramycin

1984

Comparison of standard versus pharmacokinetically adjusted amikacin dosing in granulocytopenic cancer patients.

Antimicrobial agents and chemotherapy, 1982, Volume: 22, Issue:2

Topics: Agranulocytosis; Amikacin; Bacterial Infections; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Fever; Hearing Loss; Humans; Kanamycin; Kidney; Kinetics; Moxalactam; Neoplasms; Piperacillin; Ticarcillin

1982

Other Studies

68 other study(ies) available for kanamycin a and Hearing Loss

Article	Year
Pravastatin Administration Alleviates Kanamycin-Induced Cochlear Injury and Hearing Loss. International journal of molecular sciences, 2022, Apr-20, Volume: 23, Issue:9 Topics: Animals; Caspase 3; Cochlea; Deafness; Evoked Potentials, Auditory, Brain Stem; Hearing Loss; Kanamycin; Poly(ADP-ribose) Polymerase Inhibitors; Pravastatin; Rats	2022
A reduced form of nicotinamide riboside protects the cochlea against aminoglycoside-induced ototoxicity by SIRT1 activation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 150 Topics: 14-3-3 Proteins; Aminoglycosides; Animals; Anti-Bacterial Agents; Cochlea; Hearing Loss; Kanamycin; Mice; NAD; Niacinamide; Ototoxicity; Pyridinium Compounds; Reactive Oxygen Species; Resveratrol; Sirtuin 1	2022
Oridonin alleviates kanamycin-related hearing loss by inhibiting NLRP3/caspase-1/gasdermin D-induced inflammasome activation and hair cell pyroptosis. Molecular immunology, 2022, Volume: 149 Topics: Animals; Caspase 1; Diterpenes, Kaurane; Hair; Hearing Loss; Inflammasomes; Interleukin-1beta; Kanamycin; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Reactive Oxygen Species	2022
[Kanamycin-induced ototoxicity during treatment of multidrug-resistant tuberculosis]. Revue des maladies respiratoires, 2020, Volume: 37, Issue:5 Topics: Adult; Aminoglycosides; Antitubercular Agents; Cameroon; Female; Hearing Loss; Humans; Incidence; Kanamycin; Male; Ototoxicity; Retrospective Studies; Tuberculosis, Multidrug-Resistant	2020
Prevalence of Pre-Existing Hearing Loss Among Patients With Drug-Resistant Tuberculosis in South Africa. American journal of audiology, 2020, Jun-08, Volume: 29, Issue:2 Topics: Adolescent; Adult; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Antitubercular Agents; Audiometry; Auditory Threshold; Cross-Sectional Studies; Female; Hearing Loss; HIV Infections; Humans; Hypoalbuminemia; Kanamycin; Male; Middle Aged; Ototoxicity; Prevalence; Renal Insufficiency; South Africa; Thinness; Tuberculosis, Multidrug-Resistant; Young Adult	2020
Generation of Cochlear Hair Cells from Sox2 Positive Supporting Cells via DNA Demethylation. International journal of molecular sciences, 2020, Nov-17, Volume: 21, Issue:22 Topics: Animals; Azacitidine; DNA Methylation; Female; Furosemide; Hair Cells, Auditory; Hearing Loss; Kanamycin; Male; Mice; Mice, Transgenic; SOXB1 Transcription Factors	2020
Characterization of EGR-1 Expression in the Auditory Cortex Following Kanamycin-Induced Hearing Loss in Mice. Journal of molecular neuroscience : MN, 2021, Volume: 71, Issue:11 Topics: Animals; Auditory Cortex; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; Early Growth Response Protein 1; Evoked Potentials, Auditory, Brain Stem; Excitatory Amino Acid Antagonists; Hearing Loss; Kanamycin; Mice; Mice, Inbred CBA; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt	2021
SOD2 Alleviates Hearing Loss Induced by Noise and Kanamycin in Mitochondrial DNA4834-deficient Rats by Regulating PI3K/MAPK Signaling. Current medical science, 2021, Volume: 41, Issue:3 Topics: DNA, Mitochondrial; Gene Expression Regulation; Hearing Loss; Kanamycin; Mitochondria; Mitogen-Activated Protein Kinase Kinases; Noise; Phosphatidylinositol 3-Kinases; Signal Transduction; Superoxide Dismutase	2021
The expression of oxidative stress response genes is modulated by a combination of resveratrol and N-acetylcysteine to ameliorate ototoxicity in the rat cochlea. Hearing research, 2018, Volume: 358 Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Auditory Fatigue; Brain Stem; Cochlea; Cytoprotection; Disease Models, Animal; Drug Therapy, Combination; Evoked Potentials, Auditory, Brain Stem; Furosemide; Gene Expression Regulation; Hearing; Hearing Loss; Inflammation Mediators; Kanamycin; Male; Oxidative Stress; Rats, Wistar; Reaction Time; Resveratrol	2018
Hearing loss with kanamycin treatment for multidrug-resistant tuberculosis in Bangladesh. The European respiratory journal, 2018, Volume: 51, Issue:3 Topics: Adult; Aminoglycosides; Antitubercular Agents; Bangladesh; Body Mass Index; Cohort Studies; Female; Hearing Loss; Humans; Kanamycin; Kaplan-Meier Estimate; Male; Mycobacterium tuberculosis; Risk Factors; Tuberculosis, Multidrug-Resistant	2018
The Novel Peptide Vaccine GV1001 Protects Hearing in a Kanamycin-induced Ototoxicity Mouse Model. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2018, Volume: 39, Issue:8 Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Ear, Inner; Hair Cells, Auditory; Hearing; Hearing Loss; Kanamycin; Male; Mice; Peptide Fragments; Telomerase; Vaccines, Subunit	2018
Upregulation of HSP60 expression in the postnatal rat cochlea and rats with drug-induced hearing loss. Cell stress & chaperones, 2018, Volume: 23, Issue:6 Topics: Animals; Auditory Threshold; Chaperonin 60; Cochlea; Evoked Potentials, Auditory, Brain Stem; Furosemide; Hair Cells, Auditory; Hearing Loss; Kanamycin; Labyrinth Supporting Cells; Mitochondrial Proteins; Rats; Rats, Sprague-Dawley; Spiral Ganglion; Transcriptional Activation; Up-Regulation	2018
In vivo transcranial flavoprotein autofluorescence imaging of tonotopic map reorganization in the mouse auditory cortex with impaired auditory periphery. Hearing research, 2019, Volume: 377 Topics: Acoustic Stimulation; Animals; Auditory Cortex; Auditory Threshold; Brain Mapping; Bumetanide; Disease Models, Animal; Evoked Potentials, Auditory; Female; Flavoproteins; Hearing; Hearing Loss; Kanamycin; Mice, Inbred C57BL; Microscopy, Fluorescence; Neuronal Plasticity; Optical Imaging; Reaction Time; Time Factors	2019
Generation of new hair cells by DNA methyltransferase (Dnmt) inhibitor 5-azacytidine in a chemically-deafened mouse model. Scientific reports, 2019, 05-29, Volume: 9, Issue:1 Topics: Animals; Azacitidine; Cochlea; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; Ear, Inner; Enzyme Inhibitors; Furosemide; Hair Cells, Auditory, Inner; Hearing Loss; Humans; Kanamycin; Mice; Regeneration	2019
[Math1 gene therapy for kanamycin and furosemide-induced deaf guinea pigs]. Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 2013, Volume: 48, Issue:7 Topics: Adenoviridae; Animals; Basic Helix-Loop-Helix Transcription Factors; Cochlea; Deafness; Ear, Inner; Evoked Potentials, Auditory, Brain Stem; Furosemide; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; Guinea Pigs; Hair Cells, Auditory; Hearing Loss; Kanamycin; Perilymph	2013
Profile of adverse drug reactions in drug resistant tuberculosis from Punjab. The Indian journal of tuberculosis, 2014, Volume: 61, Issue:4 Topics: Adolescent; Adult; Aged; Antitubercular Agents; Arthralgia; Ataxia; Chemical and Drug Induced Liver Injury; Child; Cycloserine; Drug Eruptions; Drug Therapy, Combination; Ethambutol; Ethionamide; Female; Gastrointestinal Diseases; Hearing Loss; Humans; Hypothyroidism; India; Kanamycin; Levofloxacin; Male; Middle Aged; Peripheral Nervous System Diseases; Psychoses, Substance-Induced; Pyrazinamide; Severity of Illness Index; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Vision Disorders; Young Adult	2014
Aminoglycoside ototoxicity and hair cell ablation in the adult gerbil: A simple model to study hair cell loss and regeneration. Hearing research, 2015, Volume: 325 Topics: Aminoglycosides; Animals; Cochlea; Disease Models, Animal; Female; Gerbillinae; Hair Cells, Auditory, Outer; Hearing; Hearing Loss; Humans; Immunohistochemistry; Kanamycin; Male; Myelin Sheath; Phalloidine; Regeneration; Spiral Ganglion	2015
Comparing amikacin and kanamycin-induced hearing loss in multidrug-resistant tuberculosis treatment under programmatic conditions in a Namibian retrospective cohort. BMC pharmacology & toxicology, 2015, Dec-10, Volume: 16 Topics: Adolescent; Adult; Amikacin; Anti-Bacterial Agents; Body Weight; Chi-Square Distribution; Child; Child, Preschool; Coinfection; Hearing Loss; Hearing Tests; HIV Infections; Humans; Incidence; Infant; Infant, Newborn; Kanamycin; Logistic Models; Middle Aged; Namibia; Retrospective Studies; Risk Assessment; Risk Factors; Sex Factors; Tuberculosis, Multidrug-Resistant	2015
Cortical and thalamic connectivity of the auditory anterior ectosylvian cortex of early-deaf cats: Implications for neural mechanisms of crossmodal plasticity. Hearing research, 2016, Volume: 333 Topics: Acoustic Stimulation; Adaptation, Physiological; Age Factors; Animals; Auditory Cortex; Auditory Pathways; Auditory Perception; Cats; Disease Models, Animal; Hearing; Hearing Loss; Kanamycin; Neuroanatomical Tract-Tracing Techniques; Neuronal Plasticity; Photic Stimulation; Thalamus; Visual Cortex; Visual Perception	2016
Central Nervous Activity upon Systemic Salicylate Application in Animals with Kanamycin-Induced Hearing Loss--A Manganese-Enhanced MRI (MEMRI) Study. PloS one, 2016, Volume: 11, Issue:4 Topics: Amygdala; Animals; Auditory Cortex; Auditory Threshold; Cochlea; Female; Hearing Loss; Hypothalamus; Kanamycin; Magnetic Resonance Imaging; Male; Manganese; Mice; Radiography; Salicylates	2016
Clinical predictors of aminoglycoside-induced ototoxicity in drug-resistant Tuberculosis patients on intensive therapy. Auris, nasus, larynx, 2017, Volume: 44, Issue:4 Topics: Adult; Age Factors; Aminoglycosides; Antitubercular Agents; Audiometry, Pure-Tone; Body Mass Index; Coinfection; Comorbidity; Cycloserine; Diabetes Mellitus; Female; Hearing Loss; HIV Infections; Humans; Kanamycin; Levofloxacin; Male; Middle Aged; Nigeria; Prospective Studies; Prothionamide; Pyrazinamide; Risk Factors; Time Factors; Tuberculosis, Multidrug-Resistant; Young Adult	2017
Reduced Chance of Hearing Loss Associated with Therapeutic Drug Monitoring of Aminoglycosides in the Treatment of Multidrug-Resistant Tuberculosis. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:3 Topics: Adult; Amikacin; Antitubercular Agents; Area Under Curve; Audiometry; Biological Availability; Drug Administration Schedule; Drug Dosage Calculations; Drug Monitoring; Extensively Drug-Resistant Tuberculosis; Female; Hearing Loss; Humans; Kanamycin; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Retrospective Studies	2017
Comparison of different aminoglycoside antibiotic treatments to refine ototoxicity studies in adult mice. Laboratory animals, 2010, Volume: 44, Issue:2 Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Cochlea; Disease Models, Animal; Dose-Response Relationship, Drug; Evoked Potentials, Auditory, Brain Stem; Gentamicins; Hearing Loss; Kanamycin; Male; Mice; Mice, Inbred C57BL; Mortality; Neomycin	2010
Direct drug application to the round window: a comparative study of ototoxicity in rats. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2009, Volume: 141, Issue:5 Topics: Administration, Topical; Animals; Cochlea; Evoked Potentials, Auditory, Brain Stem; Furosemide; Hearing Loss; Injections, Intravenous; Injections, Subcutaneous; Kanamycin; Male; Random Allocation; Rats; Rats, Wistar; Round Window, Ear	2009
Expression of fractalkine receptor CX3CR1 on cochlear macrophages influences survival of hair cells following ototoxic injury. Journal of the Association for Research in Otolaryngology : JARO, 2010, Volume: 11, Issue:2 Topics: Animals; Auditory Threshold; Bone Marrow; Cell Survival; Cochlea; CX3C Chemokine Receptor 1; Evoked Potentials, Auditory, Brain Stem; Female; Hair Cells, Auditory, Outer; Hearing Loss; Kanamycin; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pregnancy; Protein Synthesis Inhibitors; Radiation Chimera; Receptors, Chemokine	2010
Spiral ganglion cell survival after round window membrane application of brain-derived neurotrophic factor using gelfoam as carrier. Hearing research, 2011, Volume: 272, Issue:1-2 Topics: Acoustic Stimulation; Animals; Auditory Threshold; Brain-Derived Neurotrophic Factor; Cell Shape; Cell Size; Cell Survival; Disease Models, Animal; Drug Carriers; Electric Stimulation; Evoked Potentials, Auditory, Brain Stem; Female; Furosemide; Gelatin Sponge, Absorbable; Guinea Pigs; Hearing Loss; Kanamycin; Neuroprotective Agents; Spiral Ganglion; Time Factors	2011
Comparative analysis of combination kanamycin-furosemide versus kanamycin alone in the mouse cochlea. Hearing research, 2011, Volume: 272, Issue:1-2 Topics: Acoustic Stimulation; Animals; Atrophy; Auditory Threshold; Cell Death; Cell Movement; Cochlea; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Furosemide; Hair Cells, Auditory, Outer; Hearing Loss; Kanamycin; Macrophages; Male; Mice; Mice, Inbred C57BL; Monocytes	2011
Conservation of endocochlear potential in mice with profound hearing loss induced by co-administration of kanamycin and furosemide. Laboratory animals, 2011, Volume: 45, Issue:2 Topics: Animals; Anti-Bacterial Agents; Auditory Threshold; Cell Death; Cell Survival; Cochlea; Cochlear Microphonic Potentials; Disease Models, Animal; Diuretics; Drug Combinations; Evoked Potentials, Auditory, Brain Stem; Furosemide; Hair Cells, Auditory, Inner; Hair Cells, Auditory, Outer; Hearing Loss; Kanamycin; Male; Mice; Mice, Inbred CBA; Protein Synthesis Inhibitors; Stria Vascularis; Time Factors	2011
A protective mechanism against antibiotic-induced ototoxicity: role of prestin. PloS one, 2011, Feb-25, Volume: 6, Issue:2 Topics: Animals; Anti-Bacterial Agents; Apoptosis; Cell Line; CHO Cells; Cricetinae; Cricetulus; Cytoprotection; Ear Diseases; Hair Cells, Auditory; Hearing Loss; Kanamycin; Male; Mice; Mice, Inbred BALB C; Molecular Motor Proteins	2011
[Ototoxicity of kanamycin sulfate in adult rats and its underlying mechanisms]. Sheng li xue bao : [Acta physiologica Sinica], 2011, Apr-25, Volume: 63, Issue:2 Topics: Animals; Cochlea; Evoked Potentials, Auditory, Brain Stem; Hair Cells, Auditory, Outer; Hearing Loss; Kanamycin; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Spiral Ganglion	2011
Ototoxic destruction by co-administration of kanamycin and ethacrynic acid in rats. Journal of Zhejiang University. Science. B, 2011, Volume: 12, Issue:10 Topics: Animals; Anti-Bacterial Agents; Deafness; Ear, Inner; Ethacrynic Acid; Hearing Loss; Kanamycin; Rats; Rats, Sprague-Dawley; Stria Vascularis	2011
Tanshinone (Salviae miltiorrhizae extract) preparations attenuate aminoglycoside-induced free radical formation in vitro and ototoxicity in vivo. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:6 Topics: Abietanes; Animals; Anti-Bacterial Agents; Auditory Threshold; Cochlea; Drug Interactions; Drugs, Chinese Herbal; Evoked Potentials, Auditory, Brain Stem; Free Radical Scavengers; Gentamicins; Hearing Loss; Hydroxyl Radical; Kanamycin; Lipid Peroxidation; Male; Mice; Mice, Inbred CBA; Oxidants; Phenanthrenes; Superoxides	2003
A milligram of prevention. Journal of the American Academy of Audiology, 2003, Volume: 14, Issue:3 Topics: Anti-Bacterial Agents; Hearing Loss; Hearing Loss, Noise-Induced; Humans; Kanamycin	2003
[Audiological tests in kanamycin therapy]. HNO, 1961, Volume: 9 Topics: Anti-Bacterial Agents; Audiology; Audiometry; Deafness; Hearing Loss; Humans; Kanamycin	1961
[Nil nocere: On the ototoxicity of kanamycin]. Munchener medizinische Wochenschrift (1950), 1961, Jul-21, Volume: 103 Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Deafness; Ear Diseases; Hearing Loss; Kanamycin	1961
[2 cases of deafness caused by kanamycin]. Revue d'oto-neuro-ophtalmologie, 1960, Volume: 32 Topics: Anti-Bacterial Agents; Deafness; Hearing Loss; Kanamycin	1960
The toxic effect of kanamycin on the inner ear: report of a case. Canadian Medical Association journal, 1959, Sep-01, Volume: 81 Topics: Deafness; Ear, Inner; Hearing Loss; Kanamycin	1959
Ototoxicity of neomycin and other antibiotics. The Journal of laryngology and otology, 1962, Volume: 76 Topics: Anti-Bacterial Agents; Deafness; Ear; Hearing Loss; Kanamycin; Neomycin; Polymyxins; Ristocetin; Streptomycin; Vancomycin; Viomycin	1962
The problem of ototoxicity in the treatment of tuberculosis. Tuberculology and thoracic diseases, 1963, Volume: 21 Topics: Deafness; Dihydrostreptomycin Sulfate; Ear, Inner; Hearing Loss; Humans; Kanamycin; Kidney Diseases; Neomycin; Streptomycin; Tuberculosis; Viomycin	1963
[Experimental and fine tissue studies on the ototoxicity of kanamycin]. Archiv fur Ohren-, Nasen- und Kehlkopfheilkunde, 1962, Volume: 179 Topics: Cochlea; Deafness; Ear, Inner; Hearing Loss; Kanamycin	1962
The ototoxic effects of kanamycin sulfate in infants and children. The Journal of pediatrics, 1962, Volume: 60 Topics: Craniocerebral Trauma; Deafness; Ear, Inner; Hearing Loss; Kanamycin	1962
[Bilateral deafness after instillation treatment of a preumonectomy cavity with neomycin and kanamycin]. HNO, 1963, Volume: 11 Topics: Deafness; Hearing Loss; Humans; Kanamycin; Neomycin; Pneumonectomy	1963
THE CHANGING ROLE OF THE OTOLARYNGOLOGIST IN TUBERCULOSIS: EVALUATION OF ANTIBIOTICS IN HEARING IMPAIRMENT. The Journal of the Florida Medical Association. Florida Medical Association, 1964, Volume: 51 Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Hearing Disorders; Hearing Loss; Kanamycin; Neomycin; Pantothenic Acid; Streptomycin; Toxicology; Tuberculosis; Viomycin	1964
EFFECT OF AUDITORY STIMULATION OF REPRODUCTION. IV. EXPERIMENTS OF DEAF RATS. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 116 Topics: Acoustic Stimulation; Cochlea; Deafness; Fertility; Hearing Loss; Kanamycin; Pharmacology; Rats; Research; Toxicology	1964
THE OTOTOXICITY OF KANAMYCIN. A THEORETICAL AND EXPERIMENTAL STUDY. Acta oto-rhino-laryngologica Belgica, 1964, Volume: 18 Topics: Cats; Chemical Phenomena; Chemistry; Cochlea; Deafness; Dihydrostreptomycin Sulfate; Ear, Inner; Guinea Pigs; Hearing Loss; Kanamycin; Kidney; Neomycin; Pathology; Pharmacology; Research; Streptomycin; Tinnitus; Toxicology; Viomycin	1964
The ototoxicity of kanamycin. Transactions of the American Otological Society, 1959, Volume: 47 Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Deafness; Ear, Inner; Hearing Loss; Kanamycin	1959
[Experimental research on the ototoxicity of kanamycin and the possibilities of its prevention]. HNO, 1962, Volume: 10 Topics: Ascorbic Acid; Deafness; Ear Diseases; Hearing Loss; Kanamycin	1962
[Study of the prevention of kanamycin ototoxity]. Jibi inkoka Otolaryngology, 1962, Volume: 34 Topics: Biomedical Research; Deafness; Hearing Loss; Humans; Kanamycin	1962
Intrathecal injection of HVJ-E containing HGF gene to cerebrospinal fluid can prevent and ameliorate hearing impairment in rats. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:1 Topics: Animals; Cerebrospinal Fluid; Ear, Inner; Genetic Therapy; Genetic Vectors; Hearing Loss; Hepatocyte Growth Factor; Injections, Spinal; Kanamycin; Rats; Sendai virus; Subarachnoid Space; Transfection	2004
Kanamycin alters cytoplasmic and nuclear phosphoinositide signaling in the organ of Corti in vivo. Journal of neurochemistry, 2006, Volume: 99, Issue:1 Topics: Animals; Cell Nucleus; Cytoplasm; Hair Cells, Auditory, Outer; Hearing Loss; Kanamycin; Male; Mice; Mice, Inbred CBA; Organ of Corti; Phosphatidylinositols	2006
A protein derived from the fusion of TAT peptide and FNK, a Bcl-x(L) derivative, prevents cochlear hair cell death from aminoglycoside ototoxicity in vivo. Journal of neuroscience research, 2007, May-15, Volume: 85, Issue:7 Topics: Aminoglycosides; Analysis of Variance; Animals; bcl-X Protein; Cell Death; Cochlea; Ethacrynic Acid; Evoked Potentials, Auditory, Brain Stem; Gene Products, tat; Guinea Pigs; Hair Cells, Auditory; Hearing Loss; Immunohistochemistry; Kanamycin; Male; Neuroprotective Agents; Peptide Fragments; Recombinant Fusion Proteins	2007
Adeno-associated virus-mediated Bcl-xL prevents aminoglycoside-induced hearing loss in mice. Chinese medical journal, 2007, Jul-20, Volume: 120, Issue:14 Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; bcl-X Protein; Cochlea; Dependovirus; Female; Genetic Therapy; Hearing Loss; Kanamycin; Mice; Mice, Inbred C57BL	2007
Permeability to sodium ions of the endolymph-perilymph barrier. Hearing research, 1984, Volume: 15, Issue:2 Topics: Action Potentials; Animals; Cell Membrane Permeability; Cochlear Microphonic Potentials; Electric Conductivity; Endolymph; Guinea Pigs; Hearing Loss; Hearing Loss, Noise-Induced; Hypoxia; Kanamycin; Labyrinthine Fluids; Membrane Potentials; Perilymph; Sodium	1984
The potentiation of ototoxicity when aminooxyacetic acid and kanamycin are co-administered. Hearing research, 1984, Volume: 15, Issue:2 Topics: Acetates; Aminooxyacetic Acid; Animals; Cochlea; Cochlear Microphonic Potentials; Drug Synergism; Guinea Pigs; Hair Cells, Auditory; Hearing Loss; Kanamycin; Time Factors	1984
[Amikacin-induced hearing loss in patients treated with repeated hemodialysis]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1984, Nov-05, Volume: 39, Issue:45 Topics: Adult; Amikacin; Endocarditis, Bacterial; Female; Hearing Loss; Hearing Loss, Bilateral; Humans; Kanamycin; Kidney Failure, Chronic; Male; Middle Aged; Pneumonia; Renal Dialysis	1984
Effects of N-acetylcysteine on kanamycin ototoxicity in the guinea pig. Hearing research, 1983, Volume: 9, Issue:3 Topics: Acetylcysteine; Action Potentials; Animals; Drug Synergism; Free Radicals; Guinea Pigs; Hair Cells, Auditory; Hearing; Hearing Loss; Kanamycin	1983
Acoustic reflex after experimental lesions to inner and outer hair cells. Hearing research, 1982, Volume: 6, Issue:1 Topics: Animals; Auditory Threshold; Hair Cells, Auditory; Hair Cells, Auditory, Inner; Hearing Loss; Hearing Loss, Noise-Induced; Kanamycin; Rabbits; Reflex, Acoustic	1982
Renal and Auditory toxic effects of amikacin in children with cancer. American journal of diseases of children (1960), 1982, Volume: 136, Issue:3 Topics: Adolescent; Amikacin; Bacterial Infections; Child; Child, Preschool; Hearing Loss; Hearing Loss, High-Frequency; Humans; Infant; Kanamycin; Kidney Diseases; Neoplasms	1982
[Effect of ligustrazine on kanamycin ototoxicity]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1995, Volume: 15, Issue:10 Topics: Animals; Auditory Threshold; Cochlea; Female; Free Radical Scavengers; Guinea Pigs; Hearing Loss; Kanamycin; Male; Malondialdehyde; Pyrazines; Superoxide Dismutase	1995
N-methyl-D-aspartate antagonists limit aminoglycoside antibiotic-induced hearing loss. Nature medicine, 1996, Volume: 2, Issue:12 Topics: Animals; Anti-Bacterial Agents; Cochlea; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Guinea Pigs; Hair Cells, Auditory; Hearing Loss; Hearing Tests; Kanamycin; Male; N-Methylaspartate; Neomycin; Piperidines; Prosencephalon; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	1996
Recovery of hearing and vocal behavior after hair-cell regeneration. Proceedings of the National Academy of Sciences of the United States of America, 1997, Dec-09, Volume: 94, Issue:25 Topics: Animals; Auditory Perception; Auditory Threshold; Conditioning, Psychological; Discrimination, Psychological; Hair Cells, Auditory; Hearing; Hearing Loss; Humans; Kanamycin; Learning; Male; Parakeets; Regeneration; Time Factors; Vocalization, Animal	1997
Acute effects of combined administration of kanamycin and furosemide on the stria vascularis studied by distortion product otoacoustic emission and transmission electron microscopy. The Tohoku journal of experimental medicine, 1998, Volume: 186, Issue:2 Topics: Animals; Anti-Bacterial Agents; Diuretics; Drug Synergism; Furosemide; Guinea Pigs; Hearing Loss; Kanamycin; Microscopy, Electron; Otoacoustic Emissions, Spontaneous; Stria Vascularis	1998
Hearing thresholds with outer and inner hair cell loss. American journal of otolaryngology, 1979,Fall, Volume: 1, Issue:1 Topics: Animals; Audiometry; Auditory Threshold; Cell Count; Dihydrostreptomycin Sulfate; Erythrocebus patas; Guinea Pigs; Hair Cells, Auditory; Hair Cells, Auditory, Inner; Hearing Loss; Hearing Loss, Noise-Induced; Kanamycin; Macaca; Neomycin	1979
Results of hearing testing at 7-year follow-up of kanamycin-treated newborn infants. ORL; journal for oto-rhino-laryngology and its related specialties, 1978, Volume: 40, Issue:5 Topics: Audiometry; Bacterial Infections; Child; Female; Follow-Up Studies; Hearing; Hearing Loss; Hearing Tests; Humans; Infant, Newborn; Infant, Newborn, Diseases; Kanamycin; Male	1978
Kanamycin induced low-frequency hearing loss in the budgerigar (Melopsittacus undulatus). The Journal of the Acoustical Society of America, 1989, Volume: 85, Issue:1 Topics: Animals; Audiometry; Auditory Fatigue; Auditory Threshold; Dose-Response Relationship, Drug; Hearing Loss; Kanamycin; Male; Parakeets; Psittaciformes	1989
Nutritional status, glutathione levels, and ototoxicity of loop diuretics and aminoglycoside antibiotics. Hearing research, 1987, Dec-31, Volume: 31, Issue:3 Topics: Animals; Chinchilla; Cochlea; Deafness; Drug Synergism; Ethacrynic Acid; Evoked Potentials, Auditory; Food Deprivation; Glutathione; Hearing Loss; Inactivation, Metabolic; Kanamycin; Liver; Nutritional Status	1987
Ototoxicity of kanamycin in albino and pigmented guinea pigs. I. A morphologic and electrophysiologic study. The American journal of otology, 1986, Volume: 7, Issue:1 Topics: Animals; Audiometry, Evoked Response; Guinea Pigs; Hair Cells, Auditory; Hair Cells, Auditory, Inner; Hearing Loss; Kanamycin; Male; Melanins	1986
[Measurement of an auditory impairment induced by aminoglycosides using a shuttle box method in newborn rats]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 86, Issue:6 Topics: Animals; Animals, Newborn; Auditory Threshold; Avoidance Learning; Conditioning, Classical; Female; Hearing Loss; Hearing Tests; Kanamycin; Male; Rats; Rats, Inbred Strains; Streptomycin; Toxicology	1985