Page last updated: 2024-08-17

kanamycin a and Deafness

kanamycin a has been researched along with Deafness in 139 studies

Research

Studies (139)

Timeframe	Studies, this research(%)	All Research%
pre-1990	74 (53.24)	18.7374
1990's	16 (11.51)	18.2507
2000's	21 (15.11)	29.6817
2010's	24 (17.27)	24.3611
2020's	4 (2.88)	2.80

Authors

Authors	Studies
Bako, P; Gerlinger, I; Löwenheim, H; Müller, M; Wolpert, S	1
Jeon, J; Kim, SY; Lee, CH; Lee, SM	1
Chen, F; Chen, J; Li, W; Liu, Z; Mi, W; Qiu, J; Wang, R; Xing, W; Yan, H; Zha, D	1
Klis, SFL; Ramekers, D; Versnel, H	1
Astolfi, L; Bettini, S; Franceschini, V; Martini, A; Mazzanti, B; Revoltella, RP; Simoni, E	1
Chi, F; Cong, N; Gu, Y; Han, Z; Ma, R; Wang, C	1
Cai, X; Fan, G; Kong, W; Sun, H; Tu, Y	1
Grolman, W; Hendriksen, FG; Klis, SF; Ramekers, D; Van Deurzen, MH; Waaijer, L	1
Duan, M; Jing, Y; Wei, J; Zheng, G; Zhu, K; Zhu, Z	1
Gao, J; Guo, WW; Han, DY; Li, Z; Sun, AL; Sun, DX; Sun, JH; Wei, XN; Yang, SM; Zhang, XF	1
Bailey, EM; Green, SH	1
Grolman, W; Havenith, S; Klis, SF; Versnel, H	1
Illing, RB; Rauch, AK; Rosskothen-Kuhl, N	1
Jang, JH; Lee, HS; Oh, SH; Park, MH	1
Heeringa, AN; Raphael, Y; Shore, SE; Stefanescu, RA	1
Gong, SS; Guo, JY; Liu, YY; Peng, Z; Wang, GP; Wu, Q; Xie, J	1
Fallon, JB; Irvine, DR; Irving, S; Pannu, SS; Shepherd, RK; Tooker, AC; Wise, AK	1
Bertolaso, L; Cilli, M; Ciorba, A; Franceschini, V; Giordano, P; Hatzopoulos, S; Jeffery, R; Lorito, G; Magosso, S; Martini, A; Michelini, M; Ognio, E; Papini, S; Poulsom, R; Revoltella, RP; Rosellini, A; Saccardi, R; Simoni, E; Urbani, S	1
Hughes, LF; Nannapaneni, N; Shore, S; Zeng, C; Zhou, J	1
Agterberg, MJ; de Groot, JC; Klis, SF; van Dijk, LM; Versnel, H	1
Campbell, S; Oesterle, EC	1
Kim, TS; Lefebvre, PP; Malgrange, B; Nguyen, L; Poirrier, AL; Van den Ackerveken, P; Vandenbosch, R	1
Fan, GR; Huang, X; Kong, WJ; Yang, Y; Yin, ZD	1
Fan, GR; Huang, X; Kong, WJ; Li, D; Yin, ZD	1
Fallon, JB; Landry, TG; Shepherd, RK; Wise, AK	1
Ding, DL; Jiang, HY; Liu, H; Salvi, R; Sun, H; Wu, XW	1
Ge, S; Peng, A; Wang, Q; Wu, W; Xiao, Z; Xie, D	1
Hampson, AJ; Heffer, LF; Li, J; Millard, RE; Minter, RL; Niasari, A; O'Leary, SJ; Sly, DJ; Winata, L	1
Illing, RB; Rosskothen-Kuhl, N	1
Esser, KH; Gross, G; Hoffmann, A; Lenarz, T; Paasche, G; Reich, U; Sasse, S; Scheper, V; Stöver, T; Warnecke, A; Wenzel, GI; Wissel, K	1
Kng, W; Yin, Z	1
Agterberg, MJ; de Groot, JC; Grolman, W; Klis, SF; Ramekers, D; van Loon, MC; Versnel, H	1
Chomskii, AN; Ivanov, AG; Lopotko, AI; Nurskii, KV; Tomson, VV; Zhuravskii, SG	1
Bartlett, PF; Clark, GM; Gillespie, LN; Marzella, PL	1
Dong, J; Kong, W; Liu, J	1
Kondo, K; Miyajima, C; Suzuki, M; Yamasoba, T	1
PARTSCH, CJ	2
BONNEVILLE, J; WAYOFF, M	1
BRUNELLE, P	1
LEACH, W	1
FROST, JO	1
BECK, C; KRAHL, P	1
BANGS, J; BANGS, T; STEPHENSON, W; TENGG, NE; YOW, MD	1
BREUNINGER, H	1
KRAHL, P	2
CENZI, P; MEO, G	1
LINDSAY, JR; PERLMAN, HB	1
PRUDENTECORREA, A	1
WALKER, EA	1
SCHINDEL, L	1
TAMARI, I; ZONDEK, B	1
DEGREEF, I	1
HAWKINS, JE	1
OWADA, K; SHIDA, K; WAKAZAWA, T	1
Delgutte, B; Eddington, DK; Litvak, LM; Smith, ZM	1
Delgutte, B; Eddington, D; Litvak, L	1
Abbas, PJ; Hu, N; Miller, CA; Nourski, KV	1
Altschuler, RA; Miller, JM; Mukaida, M; Nagase, S	1
Kong, W; Liu, J; Liu, W; Liu, Z	1
Clark, G; Hardman, J; O'leary, S; Richardson, R; Wise, AK	1
Ashayeri, H; Jafari, Z; Malayeri, S	1
Abrashkin, KA; Humayun, N; Lee, VA; Raphael, Y; Rejali, D; Swiderski, DL	1
Agterberg, MJ; de Groot, JC; Klis, SF; Smoorenburg, GF; Versnel, H	1
Alam, SA; Green, SH; Huang, J; Robinson, BK	1
Izumikawa, M; Kim, YH; Osumi, Y; Raphael, Y	1
Altschuler, RA; Bitsche, M; Glueckert, R; Miller, JM; Prieskorn, DM; Schrott-Fischer, A; Zhu, Y	1
Freeman, FR; Greer, M; Parker, RL	1
Huangfu, M; Komune, S; Snow, JB	1
Kumor, KM; Lietman, PS; McDonald, JM	1
Webster, DB; Webster, M	1
Liu, GY; Liu, RL; Liu, YC	1
Henley, CM; Rybak, LP	1
Hartmann, R; Klinke, R; Pfennigdorff, T	1
Bannister, LH; Dodson, HC; Douek, EE	1
Abbas, PJ; Miller, CA; Robinson, BK	1
Chen, Y; Clark, GM; Shepherd, RK; Xu, SA	1
Altschuler, RA; Frey, K; Miller, JM; Schacht, J; Schwartz, DR	1
Martin, RL; Shepherd, RK	1
Fan, J; Lin, Y; Song, R; Sun, D	1
Doi, K; Fujii, K; Kubo, T; Saika, T; Yamamoto, K	1
Altschuler, RA; Chi, DH; Kruszka, P; Miller, JM; O'Keeffe, LJ; Raphael, Y	1
Wu, J	1
Fang, J; Jin, X; Liu, Y; Song, R; Sun, D; Wang, Y; Wu, Y	1
Doi, K; Fujii, K; Fuse, Y; Hasegawa, T; Kubo, T	1
Inoue, H; Kimitsuki, T; Komune, S; Nakagawa, T; Uemura, T; Wakizono, S	1
Guth, PS; Stockwell, M	1
Newton, RW	1
Gnanapragasam, A	1
Iaroshevich, VI	1
Laitakari, K	1
Clark, CH	1
Gyo, K	1
Kálmán, R; László, P; Valéria, K	1
D'Arcy, PF; Harpur, ES	2
Moran, WB	1
Nakashima, T; Yamamoto, T	1
Hashino, E; Salvi, RJ; Sokabe, M; Tanaka, Y	1
Altschuler, RA; Hartshorn, DO; Miller, JM	1
Zhuang, J	1
Yu, D	1
Sheng, J	1
Hoffman, DW; Jones, KL; Rybak, LP; Whitworth, CA	1
Uziel, A	1
Jarvis, JF	1
Alleva, FR; Vernier, VG	1
Clark, WW; Pearson, RD; Stebbins, WC; Weiland, NG	1
Selavri, TV	1
Erlach, A	1
Debain, JJ; Freyss, G; Poulain, H	1
Carbon, C; Vachon, F	1
VanOmmen, RA	1
Crifò, S	1
Ilić, C; Nikolić, M; Volckov, V	1
Bewick, M; Brown, CB; Cameron, JS; Ogg, CS	1
Jones, HC	1
Harrison, JM; West, CD	1
Rindfleisch, U; Spieske, C; Thieler, H	1
Lehnhardt, E	1
Hattori, M; Ishida, H; Mizuno, S; Otani, I; Ouchi, H	1
Bunn, PA	1
Ernstson, S	1
Ichikawa, G; Kawamura, S; Miyazaki, M; Nishida, M; Sakata, E	1
Matz, GJ; Wallace, TH; Ward, PH	1
Arcieri, GM; Falco, FG; Hobson, LB; Smith, HM	1
Cramblett, HG; Eliot, DS; Sanders, DY	1
Hamilton, CH; Johnson, AH	1
Honma, T; Kawase, A; Tachiki, T; Yamada, T	1
Lawrence, R; Levin, S; Nibbe, AF	1
Toyota, B	1
Homma, T; Ishimoda, M; Kondo, M; Numakura, M; Tsuiki, T	1
Kerr, A; Schuknecht, HF	1
Duvall, AJ; Quick, CA	1
Marseillan, RF	1

Reviews

12 review(s) available for kanamycin a and Deafness

Article	Year
[Research progress of acute kanamycin sulfate-induced deafness in guinea pig]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2012, Volume: 26, Issue:10 Topics: Animals; Anti-Bacterial Agents; Cochlea; Deafness; Disease Models, Animal; Ethacrynic Acid; Guinea Pigs; Hair Cells, Auditory; Humans; Kanamycin; Neurons; Spiral Ganglion	2012
OTONEUROLOGY. Progress in neurology and psychiatry, 1963, Volume: 18 Topics: Craniocerebral Trauma; Deafness; Dihydrostreptomycin Sulfate; Enzymes; Humans; Kanamycin; Meniere Disease; Neurology; Neurotology; Nystagmus, Pathologic; Oculomotor Nerve; Otolaryngology; Reticular Formation; Stapes Surgery; Toxicology; Vertigo; Vestibule, Labyrinth	1963
[UNEXPECTED DRUG EFFECTS: KANAMYCIN]. Medizinische Monatsschrift, 1964, Volume: 18 Topics: Deafness; Drug Hypersensitivity; Hearing Disorders; Hearing Loss; Humans; Kanamycin; Kidney Diseases; Toxicology; Vestibule, Labyrinth	1964
Non-sensory cells in the deafened organ of Corti: approaches for repair. The International journal of developmental biology, 2007, Volume: 51, Issue:6-7 Topics: Animals; Anti-Bacterial Agents; Deafness; Epithelium; Ethacrynic Acid; Genetic Therapy; Hair Cells, Auditory; Kanamycin; Labyrinth Supporting Cells; Models, Biological; Neomycin; Organ of Corti; Regeneration	2007
Ototoxicity in developing mammals. Brain research. Brain research reviews, 1995, Volume: 20, Issue:1 Topics: Age Distribution; Age Factors; Animals; Animals, Newborn; Cochlea; Deafness; Diuretics; Ear, Inner; Evoked Potentials; Gentamicins; Hearing; Hearing Loss, Noise-Induced; Humans; Hypothyroidism; Infant, Newborn; Kanamycin; Noise; Rats	1995
Toxicity of aminoglycoside antibiotics. Modern veterinary practice, 1977, Volume: 58, Issue:7 Topics: Aminoglycosides; Animals; Ataxia; Cat Diseases; Cats; Deafness; Dog Diseases; Dogs; Gentamicins; Heart Rate; Kanamycin; Kidney Tubular Necrosis, Acute; Neomycin; Rabbits; Respiratory Paralysis; Streptomycin	1977
Otorhinolaryngology. Surgery, gynecology & obstetrics, 1976, Volume: 142, Issue:2 Topics: Animals; Deafness; Ear Diseases; Electrodiagnosis; Ethacrynic Acid; Fibroma; Guinea Pigs; Humans; Kanamycin; Laryngeal Neoplasms; Laryngeal Nerves; Laryngostenosis	1976
Non-genetic factors affecting hearing development. Acta oto-laryngologica. Supplementum, 1985, Volume: 421 Topics: Adult; Age Factors; Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Cochlea; Deafness; Female; Guinea Pigs; Hearing Loss; Hearing Loss, Noise-Induced; Humans; Hyperbilirubinemia; Hypothyroidism; Infant; Infant, Newborn; Kanamycin; Maternal-Fetal Exchange; Pregnancy; Rats	1985
[Side effects of antibiotics-aminoglycosides]. Sovetskaia meditsina, 1972, Volume: 35, Issue:7 Topics: Age Factors; Aged; Animals; Anti-Bacterial Agents; Deafness; Drug Resistance, Microbial; Ear Diseases; Female; Fetal Diseases; Gentamicins; Glycosides; Guinea Pigs; Humans; Kanamycin; Kidney; Kidney Diseases; Microscopy, Electron; Neomycin; Neuromuscular Nondepolarizing Agents; Organ of Corti; Pregnancy; Time Factors; Vestibule, Labyrinth	1972
Committee on Environmental Hazards. Noise pollution: neonatal aspects. Pediatrics, 1974, Volume: 54, Issue:4 Topics: Adrenocorticotropic Hormone; Animals; Cats; Deafness; Environmental Exposure; Gentamicins; Guinea Pigs; Hearing Loss, Noise-Induced; Heart Rate; Humans; Incubators, Infant; Infant, Newborn; Infant, Newborn, Diseases; Kanamycin; Language Development; Neomycin; Noise; Sleep; Speech; Streptomycin; Stress, Physiological; Vasomotor System	1974
[Ototoxicity of antibiotics]. HNO, 1970, Volume: 18, Issue:4 Topics: Anti-Bacterial Agents; Deafness; Gentamicins; Humans; Kanamycin; Neomycin; Organ of Corti; Petrous Bone; Streptomycin	1970
Kanamycin. The Medical clinics of North America, 1970, Volume: 54, Issue:5 Topics: Deafness; Drug Hypersensitivity; Drug Resistance, Microbial; Enterobacteriaceae Infections; Humans; Kanamycin; Kidney; Kidney Diseases; Klebsiella; Neuromuscular Diseases; Organ of Corti; Paralysis; Staphylococcal Infections; Staphylococcus; Tuberculosis; Urinary Tract Infections; Vestibulocochlear Nerve	1970

Trials

1 trial(s) available for kanamycin a and Deafness

Article	Year
High dose frusemide in acute reversible intrinsic renal failure. A preliminary communication. Scottish medical journal, 1974, Volume: 19 Suppl 1 Topics: Acute Kidney Injury; Adult; Clinical Trials as Topic; Deafness; Furosemide; Gentamicins; Humans; Kanamycin; Male; Middle Aged; Oliguria; Peritoneal Dialysis; Renal Dialysis	1974

Other Studies

126 other study(ies) available for kanamycin a and Deafness

Article	Year
The ototoxic effect of locally applied kanamycin and furosemide in guinea pigs. Journal of neuroscience methods, 2022, Apr-15, Volume: 372 Topics: Animals; Cochlea; Deafness; Furosemide; Guinea Pigs; Hair Cells, Auditory; Kanamycin; Spiral Ganglion	2022
Pravastatin Administration Alleviates Kanamycin-Induced Cochlear Injury and Hearing Loss. International journal of molecular sciences, 2022, Apr-20, Volume: 23, Issue:9 Topics: Animals; Caspase 3; Cochlea; Deafness; Evoked Potentials, Auditory, Brain Stem; Hearing Loss; Kanamycin; Poly(ADP-ribose) Polymerase Inhibitors; Pravastatin; Rats	2022
miR-182 prevented ototoxic deafness induced by co-administration of kanamycin and furosemide in rats. Neuroscience letters, 2020, 04-01, Volume: 723 Topics: Animals; Anti-Bacterial Agents; Deafness; Drug Combinations; Female; Furosemide; Kanamycin; MicroRNAs; Ototoxicity; Rats; Rats, Sprague-Dawley; Sodium Potassium Chloride Symporter Inhibitors	2020
Simultaneous rather than retrograde spiral ganglion cell degeneration following ototoxically induced hair cell loss in the guinea pig cochlea. Hearing research, 2020, Volume: 390 Topics: Animals; Auditory Threshold; Deafness; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Furosemide; Guinea Pigs; Hair Cells, Auditory; Kanamycin; Nerve Degeneration; Ototoxicity; Spiral Ganglion	2020
Human mesenchymal stromal cell therapy for damaged cochlea repair in nod-scid mice deafened with kanamycin. Cytotherapy, 2018, Volume: 20, Issue:2 Topics: Adipogenesis; Adult; Animals; Cell Proliferation; Cells, Cultured; Cochlea; Deafness; Humans; Kanamycin; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred NOD; Mice, SCID; Osteogenesis; Phenotype; Regeneration	2018
Mimic Cochlear Implant Surgery-Induced Cochlear Infection Fails to Further Damage Auditory Pathway in Deafened Guinea Pigs. Medical science monitor : international medical journal of experimental and clinical research, 2018, Aug-06, Volume: 24 Topics: Animals; Auditory Pathways; Auditory Threshold; Bacterial Infections; China; Cochlea; Cochlear Implantation; Deafness; Evoked Potentials, Auditory, Brain Stem; Guinea Pigs; Hair Cells, Auditory; Hearing Loss, Sensorineural; Kanamycin; Neurons; Otitis; Spiral Ganglion	2018
Endoplasmic reticulum stress is involved in spiral ganglion neuron apoptosis following chronic kanamycin-induced deafness. Bioscience reports, 2019, 02-28, Volume: 39, Issue:2 Topics: Animals; Apoptosis; Caspase 12; Deafness; eIF-2 Kinase; Endoplasmic Reticulum Stress; Endoribonucleases; Heat-Shock Proteins; Kanamycin; Male; Multienzyme Complexes; Neurons; Protein Serine-Threonine Kinases; Rats, Sprague-Dawley; Spiral Ganglion; Transcription Factor CHOP	2019
The peripheral processes of spiral ganglion cells after intracochlear application of brain-derived neurotrophic factor in deafened guinea pigs. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2013, Volume: 34, Issue:3 Topics: Animals; Brain-Derived Neurotrophic Factor; Deafness; Furosemide; Guinea Pigs; Hair Cells, Auditory; Kanamycin; Myelin Sheath; Nerve Degeneration; Neurons; Spiral Ganglion	2013
Therapeutic effect of adeno-associated virus (AAV)-mediated ADNF-9 expression on cochlea of kanamycin-deafened guinea pigs. Acta oto-laryngologica, 2013, Volume: 133, Issue:10 Topics: Animals; Cells, Cultured; Cochlea; Deafness; Dependovirus; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Genetic Vectors; Guinea Pigs; Hair Cells, Auditory; Kanamycin; Oligopeptides; Transfection	2013
[Math1 gene therapy for kanamycin and furosemide-induced deaf guinea pigs]. Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 2013, Volume: 48, Issue:7 Topics: Adenoviridae; Animals; Basic Helix-Loop-Helix Transcription Factors; Cochlea; Deafness; Ear, Inner; Evoked Potentials, Auditory, Brain Stem; Furosemide; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; Guinea Pigs; Hair Cells, Auditory; Hearing Loss; Kanamycin; Perilymph	2013
Postnatal expression of neurotrophic factors accessible to spiral ganglion neurons in the auditory system of adult hearing and deafened rats. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Sep-24, Volume: 34, Issue:39 Topics: Animals; Cochlear Nucleus; Deafness; Gene Expression Regulation, Developmental; Hair Cells, Auditory; Kanamycin; Nerve Growth Factors; Organ Specificity; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Spiral Ganglion	2014
Local delivery of brain-derived neurotrophic factor on the perforated round window membrane in Guinea pigs: a possible clinical application. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2015, Volume: 36, Issue:4 Topics: Animals; Brain-Derived Neurotrophic Factor; Deafness; Disease Models, Animal; Drug Administration Routes; Evoked Potentials, Auditory, Brain Stem; Female; Furosemide; Guinea Pigs; Kanamycin; Round Window, Ear	2015
Counter-regulation of the AP-1 monomers pATF2 and Fos: Molecular readjustment of brainstem neurons in hearing and deaf adult rats after electrical intracochlear stimulation. Neuroscience, 2016, Jan-28, Volume: 313 Topics: Activating Transcription Factor 2; Animals; Auditory Pathways; Brain Stem; Cochlear Implants; Deafness; Disease Models, Animal; Female; Functional Laterality; Gene Expression; Kanamycin; Neuronal Plasticity; Neurons; Phosphorylation; Proto-Oncogene Proteins c-fos; Rats, Wistar; Sensory Deprivation	2016
Efficacy of the cat deafening method: Co-administration of ethacrynic acid and kanamycin. Acta oto-laryngologica, 2016, Volume: 136, Issue:3 Topics: Animals; Cats; Deafness; Disease Models, Animal; Ethacrynic Acid; Kanamycin; Organ of Corti	2016
Altered vesicular glutamate transporter distributions in the mouse cochlear nucleus following cochlear insult. Neuroscience, 2016, Feb-19, Volume: 315 Topics: Animals; Cell Count; Cochlear Diseases; Cochlear Nucleus; Deafness; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Functional Laterality; Immunohistochemistry; Kanamycin; Mice, Inbred C57BL; Neurons; Spiral Ganglion; Vesicular Glutamate Transport Protein 1; Vesicular Glutamate Transport Protein 2	2016
E2F1-CDK1 pathway activation in kanamycin-induced spiral ganglion cell apoptosis and the protective effect of CR8. Neuroscience letters, 2016, Mar-23, Volume: 617 Topics: Animals; Anti-Bacterial Agents; Apoptosis; Caspase 9; CDC2 Protein Kinase; Deafness; E2F1 Transcription Factor; Guinea Pigs; Hair Cells, Auditory; Kanamycin; Male; Neuroprotective Agents; Purines; Pyridines; Signal Transduction; Spiral Ganglion	2016
Second spatial derivative analysis of cortical surface potentials recorded in cat primary auditory cortex using thin film surface arrays: Comparisons with multi-unit data. Journal of neuroscience methods, 2016, 07-15, Volume: 267 Topics: Acoustic Stimulation; Animals; Auditory Cortex; Auditory Perception; Cats; Cochlear Implants; Deafness; Disease Models, Animal; Electrodes, Implanted; Equipment Design; Evoked Potentials, Auditory; Kanamycin; Signal Processing, Computer-Assisted	2016
Cochlear repair by transplantation of human cord blood CD133+ cells to nod-scid mice made deaf with kanamycin and noise. Cell transplantation, 2008, Volume: 17, Issue:6 Topics: AC133 Antigen; Aged; Animals; Anti-Bacterial Agents; Antigens, CD; Chimerism; Cochlea; Deafness; Female; Fetal Blood; Glycoproteins; Hematopoietic Stem Cell Transplantation; Humans; In Situ Hybridization, Fluorescence; Kanamycin; Mice; Mice, Inbred NOD; Mice, SCID; Noise; Peptides; Transplantation, Heterologous	2008
Cochlear damage changes the distribution of vesicular glutamate transporters associated with auditory and nonauditory inputs to the cochlear nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Apr-01, Volume: 29, Issue:13 Topics: Acoustic Stimulation; Analysis of Variance; Animals; Auditory Pathways; Cell Death; Cochlear Nucleus; Deafness; Evoked Potentials, Auditory, Brain Stem; Functional Laterality; Gene Expression Regulation; Guinea Pigs; Hair Cells, Auditory; Kanamycin; Psychoacoustics; Time Factors; Vesicular Glutamate Transport Protein 1; Vesicular Glutamate Transport Protein 2; Vesicular Transport Proteins	2009
Enhanced survival of spiral ganglion cells after cessation of treatment with brain-derived neurotrophic factor in deafened guinea pigs. Journal of the Association for Research in Otolaryngology : JARO, 2009, Volume: 10, Issue:3 Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cochlear Implants; Deafness; Electric Stimulation; Evoked Potentials, Auditory, Brain Stem; Female; Furosemide; Guinea Pigs; Kanamycin; Models, Animal; Nerve Degeneration; Protein Synthesis Inhibitors; Sodium Potassium Chloride Symporter Inhibitors; Spiral Ganglion	2009
Supporting cell characteristics in long-deafened aged mouse ears. Journal of the Association for Research in Otolaryngology : JARO, 2009, Volume: 10, Issue:4 Topics: Aging; Animals; Biomarkers; Calcium-Binding Proteins; Cell Differentiation; Deafness; Diuretics; Furosemide; Hair Cells, Auditory; Humans; Intercellular Signaling Peptides and Proteins; Jagged-1 Protein; Kanamycin; Labyrinth Supporting Cells; Membrane Proteins; Mice; Protein Synthesis Inhibitors; Serrate-Jagged Proteins; SOXB1 Transcription Factors; Spiral Ganglion; Tubulin	2009
Ototoxic drugs: difference in sensitivity between mice and guinea pigs. Toxicology letters, 2010, Mar-01, Volume: 193, Issue:1 Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cisplatin; Deafness; Drug-Related Side Effects and Adverse Reactions; Evoked Potentials, Auditory, Brain Stem; Fluorescent Antibody Technique; Guinea Pigs; Hearing; Kanamycin; Male; Mice; Mice, Inbred BALB C; Neurons; Organ of Corti; Species Specificity; Spiral Ganglion; Tolonium Chloride	2010
Time course of neuronal and synaptic plasticity in dorsal cochlear nucleus of guinea pig following chronic kanamycin-induced deafness. Brain research, 2010, Apr-30, Volume: 1328 Topics: Animals; Auditory Threshold; Cochlear Nerve; Cochlear Nucleus; Deafness; Disease Models, Animal; Guinea Pigs; Hearing; Insulin-Like Growth Factor I; Kanamycin; Neuronal Plasticity; Neurotoxins; Presynaptic Terminals; Recovery of Function; RNA, Messenger; Synapses; Synaptic Transmission; Time Factors; Up-Regulation	2010
Time sequence of auditory nerve and spiral ganglion cell degeneration following chronic kanamycin-induced deafness in the guinea pig. Brain research, 2010, May-17, Volume: 1331 Topics: Animals; Chronic Disease; Cochlear Nerve; Deafness; Guinea Pigs; Kanamycin; Nerve Degeneration; Neurons; Protein Synthesis Inhibitors; Schwann Cells; Spiral Ganglion; Time	2010
Spiral ganglion neuron survival and function in the deafened cochlea following chronic neurotrophic treatment. Hearing research, 2011, Volume: 282, Issue:1-2 Topics: Acoustic Stimulation; Analysis of Variance; Animals; Auditory Threshold; Brain-Derived Neurotrophic Factor; Cell Proliferation; Cell Survival; Cochlea; Cochlear Implantation; Cytoprotection; Deafness; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Female; Guinea Pigs; Humans; Infusion Pumps, Implantable; Infusions, Parenteral; Kanamycin; Male; Neurogenesis; Neurons; Neurotrophin 3; Recombinant Proteins; Spiral Ganglion; Time Factors	2011
Ototoxic destruction by co-administration of kanamycin and ethacrynic acid in rats. Journal of Zhejiang University. Science. B, 2011, Volume: 12, Issue:10 Topics: Animals; Anti-Bacterial Agents; Deafness; Ear, Inner; Ethacrynic Acid; Hearing Loss; Kanamycin; Rats; Rats, Sprague-Dawley; Stria Vascularis	2011
[Expression of TMPRSS3 in the rat cochlea following kanamycin ototoxicity]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2011, Volume: 36, Issue:10 Topics: Animals; Anti-Bacterial Agents; Cochlea; Deafness; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Kanamycin; Male; Membrane Proteins; Rats; Rats, Sprague-Dawley; Serine Endopeptidases	2011
Brain-derived neurotrophic factor modulates auditory function in the hearing cochlea. Journal of the Association for Research in Otolaryngology : JARO, 2012, Volume: 13, Issue:1 Topics: Animals; Auditory Threshold; Brain-Derived Neurotrophic Factor; Cell Survival; Deafness; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Female; Guinea Pigs; Hearing; Infusion Pumps; Kanamycin; Male; Otoacoustic Emissions, Spontaneous; Protein Synthesis Inhibitors; Round Window, Ear; Spiral Ganglion	2012
The impact of hearing experience on signal integration in the auditory brainstem: a c-Fos study of the rat. Brain research, 2012, Jan-30, Volume: 1435 Topics: Acoustic Stimulation; Analysis of Variance; Animals; Animals, Newborn; Auditory Threshold; Cochlea; Cochlear Implants; Cochlear Nucleus; Deafness; Disease Models, Animal; Electric Stimulation; Female; Functional Laterality; Gene Expression Regulation; Inferior Colliculi; Kanamycin; Male; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Time Factors	2012
Stable release of BDNF from the fibroblast cell line NIH3T3 grown on silicone elastomers enhances survival of spiral ganglion cells in vitro and in vivo. Hearing research, 2012, Volume: 289, Issue:1-2 Topics: Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Cell Adhesion; Cell Culture Techniques; Cell Proliferation; Cell Survival; Coculture Techniques; Deafness; Disease Models, Animal; Ethacrynic Acid; Female; Fibroblasts; Genetic Vectors; Green Fluorescent Proteins; Guinea Pigs; Humans; Kanamycin; Lentivirus; Male; Mice; Neurons; NIH 3T3 Cells; Paracrine Communication; Rats; Rats, Sprague-Dawley; Silicone Elastomers; Spiral Ganglion; Time Factors; Transfection	2012
Spiral ganglion cell morphology in guinea pigs after deafening and neurotrophic treatment. Hearing research, 2013, Volume: 298 Topics: Animals; Auditory Threshold; Brain-Derived Neurotrophic Factor; Cell Shape; Cell Size; Cell Survival; Deafness; Disease Models, Animal; Female; Furosemide; Ganglia, Spinal; Guinea Pigs; Hair Cells, Auditory; Kanamycin; Nerve Degeneration; Neurons; Time Factors	2013
Protective effect of calcium channel blocker verapamil on morphological and functional state of hair cells of the organ of corti in experimental kanamycin-induced ototoxicity. Bulletin of experimental biology and medicine, 2002, Volume: 133, Issue:4 Topics: Animals; Calcium Channel Blockers; Deafness; Kanamycin; Male; Organ of Corti; Rats; Verapamil	2002
BDNF-induced survival of auditory neurons in vivo: Cessation of treatment leads to accelerated loss of survival effects. Journal of neuroscience research, 2003, Mar-15, Volume: 71, Issue:6 Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Deafness; Female; Guinea Pigs; Hair Cells, Auditory; Humans; Infusion Pumps, Implantable; Infusions, Parenteral; Kanamycin; Male; Neurons, Afferent; Time Factors	2003
[The role of mtDNA deletion in the sensitivity to aminoglycoside antibiotic induced deafness]. Zhonghua er bi yan hou ke za zhi, 2000, Volume: 35, Issue:2 Topics: Animals; Anti-Bacterial Agents; Deafness; DNA, Mitochondrial; Doxorubicin; Ear, Inner; Evoked Potentials, Auditory, Brain Stem; Female; Gene Deletion; Kanamycin; Male; Mutation; Random Allocation; Rats; Rats, Wistar	2000
Changes in cell proliferation in rat and guinea pig cochlea after aminoglycoside-induced damage. Neuroscience letters, 2003, Aug-28, Volume: 347, Issue:3 Topics: Aminoglycosides; Animals; Cell Division; Cochlea; Deafness; Ethacrynic Acid; Guinea Pigs; Hair Cells, Auditory; Kanamycin; Rats; Species Specificity	2003
[Audiological tests in kanamycin therapy]. HNO, 1961, Volume: 9 Topics: Anti-Bacterial Agents; Audiology; Audiometry; Deafness; Hearing Loss; Humans; Kanamycin	1961
[Nil nocere: On the ototoxicity of kanamycin]. Munchener medizinische Wochenschrift (1950), 1961, Jul-21, Volume: 103 Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Deafness; Ear Diseases; Hearing Loss; Kanamycin	1961
[2 cases of deafness caused by kanamycin]. Revue d'oto-neuro-ophtalmologie, 1960, Volume: 32 Topics: Anti-Bacterial Agents; Deafness; Hearing Loss; Kanamycin	1960
The toxic effect of kanamycin on the inner ear: report of a case. Canadian Medical Association journal, 1959, Sep-01, Volume: 81 Topics: Deafness; Ear, Inner; Hearing Loss; Kanamycin	1959
Ototoxicity of neomycin and other antibiotics. The Journal of laryngology and otology, 1962, Volume: 76 Topics: Anti-Bacterial Agents; Deafness; Ear; Hearing Loss; Kanamycin; Neomycin; Polymyxins; Ristocetin; Streptomycin; Vancomycin; Viomycin	1962
The problem of ototoxicity in the treatment of tuberculosis. Tuberculology and thoracic diseases, 1963, Volume: 21 Topics: Deafness; Dihydrostreptomycin Sulfate; Ear, Inner; Hearing Loss; Humans; Kanamycin; Kidney Diseases; Neomycin; Streptomycin; Tuberculosis; Viomycin	1963
[Experimental and fine tissue studies on the ototoxicity of kanamycin]. Archiv fur Ohren-, Nasen- und Kehlkopfheilkunde, 1962, Volume: 179 Topics: Cochlea; Deafness; Ear, Inner; Hearing Loss; Kanamycin	1962
The ototoxic effects of kanamycin sulfate in infants and children. The Journal of pediatrics, 1962, Volume: 60 Topics: Craniocerebral Trauma; Deafness; Ear, Inner; Hearing Loss; Kanamycin	1962
[Bilateral deafness after instillation treatment of a preumonectomy cavity with neomycin and kanamycin]. HNO, 1963, Volume: 11 Topics: Deafness; Hearing Loss; Humans; Kanamycin; Neomycin; Pneumonectomy	1963
[OTOTOXIC ANTIBIOTICS IN EAR DROPS, THEIR ADVANTAGES AND DISADVANTAGES]. Archiv fur Ohren-, Nasen- und Kehlkopfheilkunde, 1963, Dec-09, Volume: 182 Topics: Anti-Bacterial Agents; Cochlear Nerve; Deafness; Drug Resistance; Drug Resistance, Microbial; Ear, Inner; Kanamycin; Neomycin; Neurologic Manifestations; Streptomycin; Toxicology; Viomycin	1963
[TREATMENT OF OTOTOXIC MANIFESTATIONS DUE TO ANTITUBERCULAR ANTIBIOTIC THERAPY. CLINICAL USE OF A MONOAMINE OXIDASE INHIBITOR (NIALAMIDE)]. Gazzetta internazionale di medicina e chirurgia, 1964, Apr-15, Volume: 68 Topics: Antibiotics, Antitubercular; Antitubercular Agents; Audiometry; Cochlear Nerve; Deafness; Dihydrostreptomycin Sulfate; Kanamycin; Monoamine Oxidase Inhibitors; Nialamide; Streptomycin; Toxicology; Tuberculosis; Tuberculosis, Pulmonary; Vertigo; Vestibular Nerve; Viomycin	1964
[THE PROBLEM OF THE TOXIC ACTION OF STREPTOMYCIN AND KANAMYCIN ON AUDITORY FUNCTION]. Resenha clinico-cientifica, 1963, Volume: 32 Topics: Audiometry; Cochlea; Deafness; Kanamycin; Pharmacology; Streptomycin; Tinnitus; Toxicology; Tuberculosis; Tuberculosis, Meningeal; Tuberculosis, Pulmonary	1963
HEARING AND RELATED PROBLEMS IN CHILDHOOD. Clinical pediatrics, 1964, Volume: 3 Topics: Audiometry; Child; Cochlear Nerve; Craniocerebral Trauma; Deafness; Dihydrostreptomycin Sulfate; Electroencephalography; Encephalitis; Fetal Diseases; Humans; Hypoxia; Infant; Influenza, Human; Kanamycin; Malaria; Measles; Meningitis; Mumps; Neomycin; Oklahoma; Otitis Media; Polymyxins; Pregnancy; Quinine; Streptomycin; Toxicology; Vancomycin	1964
EFFECT OF AUDITORY STIMULATION OF REPRODUCTION. IV. EXPERIMENTS OF DEAF RATS. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 116 Topics: Acoustic Stimulation; Cochlea; Deafness; Fertility; Hearing Loss; Kanamycin; Pharmacology; Rats; Research; Toxicology	1964
THE OTOTOXICITY OF KANAMYCIN. A THEORETICAL AND EXPERIMENTAL STUDY. Acta oto-rhino-laryngologica Belgica, 1964, Volume: 18 Topics: Cats; Chemical Phenomena; Chemistry; Cochlea; Deafness; Dihydrostreptomycin Sulfate; Ear, Inner; Guinea Pigs; Hearing Loss; Kanamycin; Kidney; Neomycin; Pathology; Pharmacology; Research; Streptomycin; Tinnitus; Toxicology; Viomycin	1964
The ototoxicity of kanamycin. Transactions of the American Otological Society, 1959, Volume: 47 Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Deafness; Ear, Inner; Hearing Loss; Kanamycin	1959
[Experimental research on the ototoxicity of kanamycin and the possibilities of its prevention]. HNO, 1962, Volume: 10 Topics: Ascorbic Acid; Deafness; Ear Diseases; Hearing Loss; Kanamycin	1962
[Study of the prevention of kanamycin ototoxity]. Jibi inkoka Otolaryngology, 1962, Volume: 34 Topics: Biomedical Research; Deafness; Hearing Loss; Humans; Kanamycin	1962
Desynchronization of electrically evoked auditory-nerve activity by high-frequency pulse trains of long duration. The Journal of the Acoustical Society of America, 2003, Volume: 114, Issue:4 Pt 1 Topics: Acoustic Stimulation; Animals; Artifacts; Auditory Threshold; Cats; Cochlear Implants; Cochlear Nerve; Deafness; Electrodes, Implanted; Evoked Potentials, Auditory; Kanamycin; Loudness Perception; Mathematical Computing; Nerve Fibers; Pitch Discrimination; Signal Processing, Computer-Assisted	2003
Improved neural representation of vowels in electric stimulation using desynchronizing pulse trains. The Journal of the Acoustical Society of America, 2003, Volume: 114, Issue:4 Pt 1 Topics: Animals; Auditory Threshold; Cats; Cochlear Implants; Cochlear Nerve; Deafness; Electrodes, Implanted; Humans; Kanamycin; Mathematical Computing; Nerve Fibers; Phonetics; Reaction Time; Signal Processing, Computer-Assisted; Sound Spectrography; Speech Acoustics; Speech Perception; Stochastic Processes	2003
Co-administration of kanamycin and ethacrynic acid as a deafening method for acute animal experiments. Hearing research, 2004, Volume: 187, Issue:1-2 Topics: Animals; Deafness; Disease Models, Animal; Drug Synergism; Ethacrynic Acid; Guinea Pigs; Kanamycin	2004
Neonatal deafening causes changes in Fos protein induced by cochlear electrical stimulation. Journal of neurocytology, 2003, Volume: 32, Issue:4 Topics: Age Factors; Animals; Animals, Newborn; Auditory Pathways; Cochlea; Cochlear Implants; Deafness; Electric Stimulation; Functional Laterality; Immunohistochemistry; Inferior Colliculi; Kanamycin; Language Development Disorders; Nerve Degeneration; Neural Conduction; Neuronal Plasticity; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spiral Ganglion	2003
[The relationship between the fragment deletion of mtDNA in old rat and the sensitivity to aminoglycoside antibiotic induced deafness]. Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology, 2004, Volume: 18, Issue:11 Topics: Animals; Anti-Bacterial Agents; Deafness; DNA, Mitochondrial; Ear, Inner; Evoked Potentials, Auditory, Brain Stem; Gene Deletion; Kanamycin; Rats; Rats, Wistar	2004
Resprouting and survival of guinea pig cochlear neurons in response to the administration of the neurotrophins brain-derived neurotrophic factor and neurotrophin-3. The Journal of comparative neurology, 2005, Jun-27, Volume: 487, Issue:2 Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Count; Cell Survival; Cochlea; Cochlear Implantation; Deafness; Disease Models, Animal; Furosemide; GAP-43 Protein; Guinea Pigs; Immunohistochemistry; Kanamycin; Models, Biological; Nerve Degeneration; Nerve Regeneration; Neurofilament Proteins; Neurons, Afferent; Neurotrophin 3; Time Factors	2005
The ages of suspicion, diagnosis, amplification, and intervention in deaf children. International journal of pediatric otorhinolaryngology, 2007, Volume: 71, Issue:1 Topics: Age Distribution; Anti-Bacterial Agents; Birth Weight; Child, Preschool; Consanguinity; Cross-Sectional Studies; Deafness; Female; Gentamicins; Hearing Aids; Humans; Hyperbilirubinemia; Incubators, Infant; Infant; Intensive Care Units, Neonatal; Iran; Kanamycin; Male; Measles; Meningitis; Mumps; Pregnancy; Pregnancy Complications; Risk Factors; Rubella; Socioeconomic Factors; Surveys and Questionnaires	2007
Cochlear implants and ex vivo BDNF gene therapy protect spiral ganglion neurons. Hearing research, 2007, Volume: 228, Issue:1-2 Topics: Adenoviridae; Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cochlear Implantation; Cochlear Implants; Deafness; Disease Models, Animal; Ethacrynic Acid; Feasibility Studies; Fibroblasts; Genetic Therapy; Genetic Vectors; Guinea Pigs; Kanamycin; Nerve Degeneration; Neurons; Prosthesis Design; Sepharose; Spiral Ganglion; Transduction, Genetic	2007
Time course of cochlear electrophysiology and morphology after combined administration of kanamycin and furosemide. Hearing research, 2007, Volume: 231, Issue:1-2 Topics: Action Potentials; Animals; Anti-Bacterial Agents; Cell Survival; Cochlea; Deafness; Electrophysiology; Female; Furosemide; Ganglia; Ganglia, Spinal; Guinea Pigs; Hair Cells, Auditory; Kanamycin; Sodium Potassium Chloride Symporter Inhibitors	2007
Prosurvival and proapoptotic intracellular signaling in rat spiral ganglion neurons in vivo after the loss of hair cells. The Journal of comparative neurology, 2007, Aug-20, Volume: 503, Issue:6 Topics: Animals; Anti-Bacterial Agents; Apoptosis; Blotting, Western; Cell Survival; Cyclic AMP Response Element-Binding Protein; Deafness; Fluorescent Antibody Technique; Hair Cells, Auditory; Image Processing, Computer-Assisted; Immunohistochemistry; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Kanamycin; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; Spiral Ganglion	2007
Deafferentation-associated changes in afferent and efferent processes in the guinea pig cochlea and afferent regeneration with chronic intrascalar brain-derived neurotrophic factor and acidic fibroblast growth factor. The Journal of comparative neurology, 2008, Apr-01, Volume: 507, Issue:4 Topics: Animals; Auditory Pathways; Brain-Derived Neurotrophic Factor; Cochlea; Deafness; Enzyme Inhibitors; Ethacrynic Acid; Female; Fibroblast Growth Factor 1; Guinea Pigs; Image Processing, Computer-Assisted; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Kanamycin; Male; Microscopy, Confocal; Microscopy, Electron, Transmission; Nerve Regeneration; Neurons; Neurons, Afferent; Neurons, Efferent; Parvalbumins; Protein Synthesis Inhibitors; Synaptophysin; Time	2008
Unusual neurotoxicity of kanamycin. JAMA, 1967, May-01, Volume: 200, Issue:5 Topics: Aged; Audiometry; Deafness; Humans; Injections, Spinal; Kanamycin; Male; Nervous System Diseases; Organ of Corti; Paralysis; Physical Therapy Modalities	1967
Mechanism of the production of the negative endocochlear DC potential in the guinea pig. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1983, Volume: 91, Issue:4 Topics: Animals; Cochlea; Cochlear Microphonic Potentials; Deafness; Endolymph; Evoked Potentials, Auditory; Guinea Pigs; Hypoxia; Kanamycin; Mathematics; Potassium	1983
Effect of 'high-dose' amikacin in children. Developmental pharmacology and therapeutics, 1984, Volume: 7, Issue:6 Topics: Adolescent; Amikacin; Bacterial Infections; Child; Child, Preschool; Creatinine; Deafness; Hearing; Hearing Loss, Bilateral; Humans; Infant; Kanamycin; Kidney; Time Factors	1984
Multipolar spiral ganglion neurons following organ of Corti loss. Brain research, 1982, Jul-29, Volume: 244, Issue:2 Topics: Animals; Cochlea; Deafness; Denervation; Ethacrynic Acid; Guinea Pigs; Kanamycin; Nerve Regeneration; Neurons; Organ of Corti; Spiral Ganglion	1982
[Effects of poria cocos on ototoxicity induced by kanamycin in guinea-pigs]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1995, Volume: 15, Issue:7 Topics: Animals; Deafness; Drugs, Chinese Herbal; Evoked Potentials, Auditory, Brain Stem; Female; Guinea Pigs; Hair Cells, Auditory, Outer; Kanamycin; Male; Reflex, Acoustic	1995
Evoked potentials from the auditory nerve following sinusoidal electrical stimulation of the cochlea: new possibilities for preoperative testing in cochlear-implant candidates? Acta oto-laryngologica, 1994, Volume: 114, Issue:5 Topics: Acoustic Stimulation; Action Potentials; Animals; Artifacts; Cats; Cochlea; Cochlear Implants; Deafness; Disease Models, Animal; Electric Stimulation; Ethacrynic Acid; Evoked Potentials, Auditory, Brain Stem; Humans; Kanamycin; Neomycin; Vestibulocochlear Nerve	1994
Effects of unilateral deafening on the cochlear nucleus of the guinea pig at different ages. Brain research. Developmental brain research, 1994, Jul-15, Volume: 80, Issue:1-2 Topics: Aging; Animals; Brain Stem; Cell Size; Cochlear Nucleus; Deafness; Functional Laterality; Guinea Pigs; Kanamycin; Neurons, Afferent	1994
Characterization of wave I of the electrically evoked auditory brainstem response in the guinea pig. Hearing research, 1993, Volume: 69, Issue:1-2 Topics: Animals; Cochlea; Cochlear Implants; Deafness; Electric Stimulation; Evoked Potentials, Auditory, Brain Stem; Guinea Pigs; Hair Cells, Auditory; Humans; Kanamycin; Nerve Degeneration; Vestibulocochlear Nerve	1993
Profound hearing loss in the cat following the single co-administration of kanamycin and ethacrynic acid. Hearing research, 1993, Volume: 70, Issue:2 Topics: Animals; Cats; Cochlea; Deafness; Dendrites; Disease Models, Animal; Dose-Response Relationship, Drug; Ethacrynic Acid; Evoked Potentials, Auditory, Brain Stem; Hair Cells, Auditory; Kanamycin; Kidney; Organ of Corti; Spiral Ganglion	1993
Chronic electrical stimulation reverses deafness-related depression of electrically evoked 2-deoxyglucose activity in the guinea pig inferior colliculus. Hearing research, 1993, Volume: 70, Issue:2 Topics: Animals; Cochlea; Cochlear Implants; Deafness; Deoxyglucose; Electric Stimulation; Electrodes, Implanted; Ethacrynic Acid; Evoked Potentials, Auditory, Brain Stem; Guinea Pigs; Inferior Colliculi; Kanamycin	1993
Onset of ototoxicity in the cat is related to onset of auditory function. Hearing research, 1995, Volume: 92, Issue:1-2 Topics: Aging; Animals; Anti-Bacterial Agents; Audiometry; Auditory Cortex; Auditory Threshold; Cats; Cochlea; Deafness; Diuretics; Drug Synergism; Ethacrynic Acid; Evoked Potentials, Auditory, Brain Stem; Hearing Loss, High-Frequency; Kanamycin	1995
[Treatment of ototoxic auditory damage caused by kanamycin with electroacupuncture at different acupoints]. Zhen ci yan jiu = Acupuncture research, 1995, Volume: 20, Issue:3 Topics: Animals; Anti-Bacterial Agents; Deafness; Electroacupuncture; Guinea Pigs; Hair Cells, Auditory; Kanamycin	1995
Electrically evoked auditory brainstem response and Fos-immunoreactivity in kanamycin-deafened rats. Advances in oto-rhino-laryngology, 1997, Volume: 52 Topics: Acoustic Stimulation; Animals; Animals, Newborn; Cochlear Nucleus; Deafness; Electrodes, Implanted; Evoked Potentials, Auditory, Brain Stem; Hearing; Immunohistochemistry; Kanamycin; Neurons; Rats	1997
Neurotrophins can enhance spiral ganglion cell survival after inner hair cell loss. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1997, Volume: 15, Issue:4-5 Topics: Animals; Anti-Bacterial Agents; Antimetabolites; Brain-Derived Neurotrophic Factor; Cell Survival; Cochlea; Deafness; Guinea Pigs; Hair Cells, Auditory, Inner; Kanamycin; Nerve Growth Factors; Neurotrophin 3; Organ of Corti; Peripheral Nervous System; Spiral Ganglion	1997
[Cross susceptibility of ototoxicity about aminoglycoside antibiotics]. Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology, 1997, Volume: 11, Issue:1 Topics: Adolescent; Adult; Anti-Bacterial Agents; Deafness; Disease Susceptibility; Family Health; Female; Gentamicins; Humans; Kanamycin; Male; Pedigree	1997
An experimental study of electro-acupuncture on auditory impairment caused by kanamycin in guinea pigs. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 1999, Volume: 19, Issue:1 Topics: Animals; Anti-Bacterial Agents; Cochlea; Deafness; Electroacupuncture; Evoked Potentials, Auditory, Brain Stem; Guinea Pigs; Kanamycin; Succinate Dehydrogenase	1999
Expression of glutamate receptors in the cochlea of the normal and kanamycin-deaf rats. Advances in oto-rhino-laryngology, 2000, Volume: 57 Topics: Animals; Deafness; Gene Expression Regulation; Hair Cells, Auditory; Kanamycin; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; RNA, Messenger; Spiral Ganglion	2000
Profiles of resting potentials across the stria vascularis in kanamycin-deafened guinea pigs. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1994, Volume: 251 Suppl 1 Topics: Animals; Anti-Bacterial Agents; Deafness; Evoked Potentials; Guinea Pigs; Hypoxia; Kanamycin; Stria Vascularis	1994
Guanylate cyclase and cyclic guanosine monophosphate in the guinea-pig cochlea. Journal of neurochemistry, 1977, Volume: 28, Issue:1 Topics: Animals; Cochlea; Cochlear Nerve; Cyclic AMP; Cyclic GMP; Deafness; Ethacrynic Acid; Guanylate Cyclase; Guinea Pigs; Kanamycin; Olivary Nucleus	1977
Side effects of drugs used to treat tuberculosis. Scottish medical journal, 1975, Volume: 20, Issue:2 Topics: Aminosalicylic Acids; Animals; Antitubercular Agents; Capreomycin; Chemical and Drug Induced Liver Injury; Cycloserine; Deafness; Drug Hypersensitivity; Ethambutol; Ethionamide; Gastrointestinal Diseases; Goiter; Humans; Isoniazid; Kanamycin; Liver; Mental Disorders; Mice; Nervous System Diseases; Pyrazinamide; Rifampin; Streptomycin; Thioacetazone; Tuberculosis; Viomycin	1975
Ototoxic therapeutic agents. The Medical journal of Malaysia, 1975, Volume: 29, Issue:4 Topics: Animals; Anti-Bacterial Agents; Chloramphenicol; Deafness; Dihydrostreptomycin Sulfate; Ethacrynic Acid; Female; Humans; Infant, Newborn; Kanamycin; Neomycin; Pregnancy; Quinine; Salicylates; Streptomycin	1975
[Ototoxicity of some drug agents]. Voenno-meditsinskii zhurnal, 1975, Issue:10 Topics: Age Factors; Aminoglycosides; Bleomycin; Cochlea; Deafness; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Ear; Ethacrynic Acid; Furosemide; Hearing Disorders; Humans; Kanamycin; Neomycin; Streptomycin; Toxicology; Vestibule, Labyrinth; Viomycin	1975
Vestibular disorders in medically managed chronic renal insufficiency. Acta oto-laryngologica. Supplementum, 1977, Volume: 349 Topics: Adolescent; Adult; Aged; Audiometry; Caloric Tests; Deafness; Ear; Electronystagmography; Female; Furosemide; Hearing Disorders; Humans; Kanamycin; Kidney Failure, Chronic; Labyrinth Diseases; Male; Middle Aged; Streptomycin; Vestibular Function Tests; Vestibule, Labyrinth	1977
[Electrically and acoustically evoked brain stem responses in normal and KM deaf guinea pigs (author's transl)]. Nihon Jibiinkoka Gakkai kaiho, 1979, Jan-20, Volume: 82, Issue:1 Topics: Acoustic Stimulation; Animals; Auditory Perception; Brain Stem; Deafness; Electric Stimulation; Guinea Pigs; Kanamycin	1979
[Toxic hearing damage caused by antibiotics]. Orvosi hetilap, 1977, Jan-09, Volume: 118, Issue:2 Topics: Aged; Anti-Bacterial Agents; Deafness; Erythromycin; Female; Humans; Kanamycin; Male; Neomycin; Penicillins	1977
Comparison of the ototoxic effect of kanamycin on albino and pigmented rats, studied using an operant method. Experientia, 1976, Dec-15, Volume: 32, Issue:12 Topics: Acoustic Stimulation; Albinism; Animals; Deafness; Discrimination Learning; Kanamycin; Male; Rats	1976
[Negative DC resting potential inside the organ of Corti of the kanamycin-poisoned guinea pig (author's transl)]. Nihon Jibiinkoka Gakkai kaiho, 1975, Feb-20, Volume: 78, Issue:2 Topics: Animals; Deafness; Electrophysiology; Guinea Pigs; Kanamycin; Organ of Corti	1975
Hair cell regeneration in the adult budgerigar after kanamycin ototoxicity. Hearing research, 1992, Volume: 59, Issue:1 Topics: Animals; Auditory Threshold; Deafness; Hair Cells, Auditory; Kanamycin; Microscopy, Electron, Scanning; Microvilli; Parrots; Regeneration; Species Specificity; Time Factors	1992
Protective effect of electrical stimulation in the deafened guinea pig cochlea. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1991, Volume: 104, Issue:3 Topics: Animals; Auditory Threshold; Cell Nucleus; Cell Survival; Cytoplasm; Deafness; Electric Stimulation; Electrodes, Implanted; Ethacrynic Acid; Evoked Potentials, Auditory; Guinea Pigs; Hair Cells, Auditory; Kanamycin; Reaction Time; Scala Tympani; Spiral Ganglion	1991
[Factors causing deafness in deaf-mute students]. Zhonghua er bi yan hou ke za zhi, 1989, Volume: 24, Issue:4 Topics: Child, Preschool; Deafness; Female; Gentamicins; Humans; Infant; Kanamycin; Male; Streptomycin	1989
[Effect of kanamycin on the cochleas in guinea pigs]. Zhonghua er bi yan hou ke za zhi, 1989, Volume: 24, Issue:4 Topics: Animals; Cochlea; Cochlear Microphonic Potentials; Cyclic AMP; Cyclic GMP; Deafness; Ear, Inner; Guinea Pigs; Kanamycin	1989
[A pedigree analysis of aminoglycoside antibiotic ototoxicity in 43 families]. Zhonghua er bi yan hou ke za zhi, 1988, Volume: 23, Issue:3 Topics: Anti-Bacterial Agents; Child; Child, Preschool; Deafness; Gentamicins; Humans; Infant; Kanamycin; Pedigree; Streptomycin	1988
Nutritional status, glutathione levels, and ototoxicity of loop diuretics and aminoglycoside antibiotics. Hearing research, 1987, Dec-31, Volume: 31, Issue:3 Topics: Animals; Chinchilla; Cochlea; Deafness; Drug Synergism; Ethacrynic Acid; Evoked Potentials, Auditory; Food Deprivation; Glutathione; Hearing Loss; Inactivation, Metabolic; Kanamycin; Liver; Nutritional Status	1987
Screening drugs for ototoxicity. The Journal of pharmacy and pharmacology, 1972, Volume: 24 Topics: Animals; Deafness; Ethacrynic Acid; Injections, Intraperitoneal; Injections, Intravenous; Kanamycin; Mice; Mice, Inbred DBA	1972
Some aspects of the oto-toxic antibiotics. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1968, Oct-05, Volume: 42, Issue:38 Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anti-Bacterial Agents; Child; Cochlea; Deafness; Dihydrostreptomycin Sulfate; Female; Humans; Kanamycin; Male; Organ of Corti; Streptomycin; Tinnitus	1968
The bioassay of kanamycin auditory toxicity. Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 176, Issue:1 Topics: Animals; Auditory Perception; Biological Assay; Deafness; Dihydrostreptomycin Sulfate; Female; Kanamycin; Kidney; Neomycin; Postural Balance; Rats; Reflex; Streptomycin; Vestibular Function Tests	1968
Noise-and drug-induced hearing loss in monkeys. Advances in oto-rhino-laryngology, 1973, Volume: 20 Topics: Acoustic Stimulation; Animals; Auditory Threshold; Conditioning, Operant; Deafness; Disease Models, Animal; Haplorhini; Hearing Loss, Noise-Induced; Kanamycin; Macaca; Methods; Neomycin; Papio; Quinidine; Sodium Salicylate; Time Factors	1973
[Clinical studies of cochleotoxicosis due to viomycin and kanamycin during tuberculostatic treatment (a prophylactic attempt)]. Monatsschrift fur Ohrenheilkunde und Laryngo-Rhinologie, 1968, Volume: 102, Issue:11 Topics: Adult; Aged; Audiometry; Cochlea; Deafness; Humans; Kanamycin; Labyrinth Diseases; Male; Nialamide; Tuberculosis; Viomycin	1968
[Gentamicin and auricular toxicity]. Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris, 1969, Volume: 86, Issue:9 Topics: Adult; Animals; Audiometry; Deafness; Ear Diseases; Ear, Inner; Female; Gentamicins; Guinea Pigs; Histocytochemistry; Humans; Kanamycin; Kidney Failure, Chronic; Labyrinthine Fluids; Neomycin; Organ of Corti; Streptomycin; Vertigo; Vestibular Function Tests; Viomycin	1969
[Reputedly nephrotoxic antibiotic therapy during severe infections]. La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1972, Jul-10, Volume: 48, Issue:31 Topics: Acute Kidney Injury; Adolescent; Adult; Amphotericin B; Anti-Bacterial Agents; Bacterial Infections; Colistin; Deafness; Endocarditis, Bacterial; Female; Humans; Kanamycin; Kidney; Kidney Function Tests; Male; Middle Aged; Pseudomonas Infections; Sepsis; Staphylococcal Infections; Streptococcal Infections; Urea; Vancomycin	1972
Untoward effects of antimicrobial agents on major organ systems. The Medical clinics of North America, 1974, Volume: 58, Issue:3 Topics: Agranulocytosis; Amphotericin B; Anemia, Aplastic; Anemia, Hemolytic; Anti-Bacterial Agents; Ataxia; Bacitracin; Cardiovascular Diseases; Chemical and Drug Induced Liver Injury; Chloramphenicol; Deafness; Gastrointestinal Diseases; Gentamicins; Humans; Kanamycin; Kidney Diseases; Leukopenia; Lung Diseases; Neomycin; Neuromuscular Diseases; Nitrofurantoin; Optic Neuritis; Peripheral Nervous System Diseases; Skin Diseases; Streptomycin; Sulfonamides; Tetracycline; Thrombocytopenia; Vertigo	1974
Identification of ototoxic drugs by guinea pig shiver audiometry. Audiology : official organ of the International Society of Audiology, 1974, Volume: 13, Issue:4 Topics: Animals; Audiometry; Auditory Threshold; Avoidance Learning; Deafness; Disease Models, Animal; Drug Evaluation, Preclinical; Ear; Ear Diseases; Electroshock; Ethacrynic Acid; Female; Guinea Pigs; Kanamycin; Male; Organ of Corti; Shivering; Sodium; Sulfates	1974
[Toxic materials and the cochleovestibular apparatus]. Medicinski glasnik, 1972, Volume: 26, Issue:2 Topics: Adult; Audiometry; Carbon Monoxide Poisoning; Cochlea; Deafness; Humans; Kanamycin; Male; Occupational Diseases; Quinine; Streptomycin; Trichloroethylene; Vestibule, Labyrinth	1972
Intrauterine ototoxicity. A case report and review of literature. Journal of the National Medical Association, 1973, Volume: 65, Issue:3 Topics: Abnormalities, Drug-Induced; Adult; Deafness; Ear; Ethacrynic Acid; Female; Fetus; Humans; Kanamycin; Maternal-Fetal Exchange; Pregnancy	1973
Drug-induced deafness. JAMA, 1973, Apr-23, Volume: 224, Issue:4 Topics: Adult; Anti-Bacterial Agents; Aspirin; Deafness; Drug-Related Side Effects and Adverse Reactions; Ethacrynic Acid; Gentamicins; Glycosides; Humans; Injections, Intravenous; Kanamycin; Male; Middle Aged; Neomycin; Paromomycin; Quinidine	1973
Transneuronal cell atrophy in the congenitally deaf white cat. The Journal of comparative neurology, 1973, Oct-15, Volume: 151, Issue:4 Topics: Acoustic Stimulation; Animals; Atrophy; Brain Stem; Cats; Cochlea; Deafness; Hearing Tests; Kanamycin; Neurons; Olivary Nucleus; Organ of Corti	1973
[Nil nocere! Irreversible loss of hearing under kanamycin treatment in kidney insufficiency]. Zeitschrift fur arztliche Fortbildung, 1974, Feb-15, Volume: 68, Issue:4 Topics: Adult; Audiometry; Deafness; Female; Humans; Kanamycin; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Male; Middle Aged; Nephrocalcinosis; Pyelonephritis; Time Factors	1974
[Effects of vitamin B1 derivatives on the hearing disorders caused by kanamycin. 2]. Virology, 1970, Volume: 42, Issue:1 Topics: Animals; Cochlea; Deafness; Kanamycin; Microscopy, Phase-Contrast; Rabbits; Thiamine	1970
Ethacrynic acid-induced hearing loss in guinea pigs. Acta oto-laryngologica, 1972, Volume: 73, Issue:6 Topics: Animals; Audiometry; Auditory Threshold; Deafness; Ethacrynic Acid; Guinea Pigs; Hearing Tests; Kanamycin	1972
[Treatment and prevention of deafness due to streptomycin and kanamycin. 2]. Nihon Jibiinkoka Gakkai kaiho, 1971, Volume: 74, Issue:2 Topics: Action Potentials; Animals; Cochlea; Deafness; Guinea Pigs; Kanamycin; Streptomycin	1971
The ototoxicity of kanamycin. A comparative histopathological study. The Laryngoscope, 1965, Volume: 75, Issue:11 Topics: Aged; Animals; Cochlea; Deafness; Female; Guinea Pigs; Humans; Kanamycin; Organ of Corti; Temporal Bone; Vestibule, Labyrinth	1965
Clinical research experience with gentamicin. Incidence of adverse reactions. The Medical journal of Australia, 1970, Jun-13, Volume: 1 Topics: Deafness; Gentamicins; Hearing Disorders; Humans; Kanamycin; Kidney Diseases; Male; Middle Aged; Neomycin; Streptomycin; Vestibular Nerve; Vestibule, Labyrinth; Vestibulocochlear Nerve	1970
Retrospective study for possible kanamycin ototoxicity among neonatal infants. The Journal of pediatrics, 1967, Volume: 70, Issue:6 Topics: Audiometry; Child, Preschool; Deafness; Escherichia coli Infections; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature, Diseases; Kanamycin; Retrospective Studies; Staphylococcal Infections; Streptococcal Infections	1967
Kanamycin ototoxicity--possible potentiation by other drugs. Southern medical journal, 1970, Volume: 63, Issue:5 Topics: Adult; Deafness; Drug Synergism; Ethacrynic Acid; Female; Humans; Kanamycin; Male; Mannitol; Middle Aged; Neomycin; Streptomycin	1970
[Severe hearing disorders caused by kanamycin]. Virology, 1970, Volume: 42, Issue:1 Topics: Adult; Child; Deafness; Ear, Inner; Female; Hearing Tests; Humans; Kanamycin; Male; Middle Aged	1970
Lung abscess secondary to vibrio fetus, malabsorption syndrome and acquired agammaglobulinemia. Chest, 1971, Volume: 60, Issue:2 Topics: Agammaglobulinemia; Carcinoma; Deafness; Female; Humans; Kanamycin; Lung Abscess; Malabsorption Syndromes; Middle Aged; Stomach Neoplasms; Thrombophlebitis; Vibrio; Vibrio Infections	1971
[Medical suit]. Nihon Ishikai zasshi. Journal of the Japan Medical Association, 1967, Jul-01, Volume: 58, Issue:1 Topics: Adult; Deafness; Female; Humans; Jurisprudence; Kanamycin	1967
[Clinical studies on kanamycin deafness]. Nihon Jibiinkoka Gakkai kaiho, 1968, Volume: 71, Issue:3 Topics: Adult; Audiometry; Deafness; Female; Humans; Kanamycin; Kidney Diseases; Streptomycin	1968
The spiral ganglion in profound deafness. Acta oto-laryngologica, 1968, Volume: 65, Issue:6 Topics: Atrophy; Deafness; Fractures, Bone; Humans; Kanamycin; Labyrinth Diseases; Organ of Corti; Otosclerosis; Syphilis, Congenital; Temporal Bone; Thrombosis; Virus Diseases	1968
Antibiotic deafness. Eye, ear, nose & throat monthly, 1968, Volume: 47, Issue:12 Topics: Age Factors; Deafness; Humans; Kanamycin; Kidney Function Tests; Male; Middle Aged	1968
Tracers and endogenous debris in delineating cochlear barriers and pathways, an experimental study. The Annals of otology, rhinology, and laryngology, 1969, Volume: 78, Issue:5 Topics: Animals; Deafness; Ferritins; Guinea Pigs; Hearing Loss, Noise-Induced; Kanamycin; Lanthanum; Lysosomes; Microscopy, Electron; Organ of Corti; Streptomycin; Thorium Dioxide; Wounds and Injuries	1969
Electrophysiological study of kanamycin and aminosidine ototoxicity in the unanesthetized guinea pig. Acta physiologica latino americana, 1965, Volume: 15, Issue:3 Topics: Animals; Anti-Bacterial Agents; Cochlea; Deafness; Guinea Pigs; Kanamycin; Vestibulocochlear Nerve	1965