kallidin and Parkinson-Disease

Kinin peptides ubiquitously occur in nervous tissue and participate in inflammatory processes associated with distinct neurological disorders. These substances have also been demonstrated to promote the oxidative stress. On the other hand, the importance of oxidative stress and inflammation has been emphasized in disorders that involve the neurodegenerative processes such as Parkinson's disease (PD). A growing number of reports have demonstrated the increased expression of kinin receptors in neurodegenerative diseases. In this study, the effect of bradykinin and des-Arg

Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; Bradykinin; Cell Differentiation; Cell Line, Tumor; Cell Survival; Cytokines; Humans; Kallidin; Kinins; Oxidative Stress; Parkinson Disease; Reactive Oxygen Species