Page last updated: 2024-08-21

kainic acid and Nerve Degeneration

kainic acid has been researched along with Nerve Degeneration in 493 studies

Research

Studies (493)

Timeframe	Studies, this research(%)	All Research%
pre-1990	77 (15.62)	18.7374
1990's	157 (31.85)	18.2507
2000's	203 (41.18)	29.6817
2010's	52 (10.55)	24.3611
2020's	4 (0.81)	2.80

Authors

Authors	Studies
Anagnostou, I; Morales, T	1
Canty, AJ; Hanson, KA; King, AE; Tian, N; Vickers, JC	1
Cao, J; Gao, M; Rui, Y; Tang, C; Wang, L; Wang, Y; Xu, B; Yan, BC; Zhang, J	1
Dhanushkodi, A; K, S; Kutty, BM; Parveen, S; Rai, KS; Senthilkumar, S; Venugopal, C	1
Gordon, RY; Khutsian, SS; Kitchigina, VF; Mikheeva, IB; Shubina, LV	1
Naderali, E; Nikbakht, F; Ofogh, SN; Rasoolijazi, H	1
Lauková, M; Shakarjian, MP; Velíšek, L; Velíšková, J	1
Albertini, MC; Ambrogini, P; Bartolini, D; Betti, M; Cuppini, R; Di Palma, M; Galati, C; Galli, F; Lattanzi, D; Minelli, A; Olivieri, F; Palma, E; Ruffolo, G; Saccomanno, S; Savelli, D; Torquato, P	1
Barbeito, CG; Nishida, F; Portiansky, EL; Sisti, MS; Zanuzzi, CN	1
Blugeon, C; Chali, F; Jourdren, L; Le Duigou, C; Marty, S; Miles, R; Milior, G; Morin-Brureau, M; Savary, E	1
Kouroupi, G; Koutsoudaki, PN; Matsas, R; Miltiadous, P; Stamatakis, A; Stylianopoulou, F	1
Chai, X; Frotscher, M; Haas, CA; Häussler, U; Kowalski, J; Münzner, G; Tinnes, S; Young, C; Zhao, S	1
Chiba, Y; Furukawa, A; Hasegawa-Ishii, S; Kawamura, N; Kita, Y; Maruyama, K; Shimada, A; Shimizu, T; Takei, S; Yoshikawa, K	1
Abushik, PA; Antonov, SM; Eaton, MJ; Sibarov, DA; Skatchkov, SN	1
Lin, KC; Wang, CC; Wang, SJ	1
Brewer, J; Bushell, TJ; Dev, KK; Millington, O; Shrestha, R	1
Ayalon, G; Bustos, D; Gogineni, A; Hanson, JE; Jubb, AM; Kirkpatrick, DS; Larson, JL; Lee, SH; Lewcock, JW; Li, H; Ngu, H; Pozniak, CD; Scearce-Levie, K; Sengupta Ghosh, A; Solanoy, H; Weimer, RM; Wu, J; Zhou, Q	1
Dittmann, J; King, AE; Southam, KA; Vickers, JC	1
Andrade, JP; Andrade, PA; do Carmo, JM; Lukoyanov, NV; Maia, GH; Quesado, JL; Soares, JI	1
Ambrogini, P; Betti, M; Ciffolilli, S; Cuppini, R; Galati, C; Galli, F; Lattanzi, D; Minelli, A; Piroddi, M	1
Arkhipov, V; Gordon, R; Kapralova, M; Pershina, E	1
Auladell, C; Beas-Zarate, C; Camins, A; de Lemos, L; Ettcheto, M; Folch, J; Gómez-Sintes, R; Junyent, F; Lucas, JJ; Pallas, M; Verdaguer, E	1
Doihara, T; Kobayashi, N; Li, C; Matsuda, S; Nabeka, H; Saito, S; Shimokawa, T; Takechi, H; Uematsu, K; Yamamiya, K	1
Blizzard, CA; Clark, JA; Dawkins, E; Dickson, TC; King, AE; Lewis, KE; Southam, KA	1
Amhaoul, H; Bertoglio, D; De Deyn, PP; Dedeurwaerdere, S; Geerts, E; Hamaide, J; Katsifis, A; Kumar-Singh, S; Reichel, SN; Staelens, S; Van Dam, D; Van Der Linden, A; Verhaeghe, J	1
Chen, X; Dong, G; Wang, H; Yun, W; Zheng, C; Zhou, X	1
Becker, AJ; Müller, JA; Schoch, S; Sowade, RF; van Loo, KM; Woitecki, AM	1
Auladell, C; Beas-Zarate, C; Busquets, O; Camins, A; de Lemos, L; Ettcheto, M; Folch, J; Lazarowski, A; Olloquequi, J; Verdaguer, E	1
Aschner, M; Gupta, RC; Milatovic, D; Montine, TJ; Zaja-Milatovic, S	1
Gröticke, I; Hoffmann, K; Löscher, W	1
Glickstein, SB; Koeller, HB; Ross, ME	1
Bai, Y; Bian, GL; Cao, R; Chen, LW; Wang, YQ	1
Binienda, Z; Bowyer, J; Cozart, M; Heard, D; Paule, M; Schmued, L	1
Behl, C; Clement, AB; Deussing, JM; Hanstein, R; Holsboer, F; Lu, A; Wurst, W	1
Bellanger, C; Chichery, R; Dickel, L; Graindorge, N; Jozet-Alves, C	1
Cho, SS; Choi, DH; Chung, CK; Jeon, GS; Kim, DW; Lee, HN	1
Chae, JS; Jeong, JH; Kim, AY; Kim, HC; Kim, SC; Kim, WK; Ko, KH; Koh, YH; Nah, SY; Shin, EJ; Yen, TP; Yoon, HJ	1
Jeong, JH; Kim, AY; Kim, HC; Kim, HJ; Kim, WK; Ko, KH; Koh, YH; Kwon, YS; Nah, SY; Shin, EJ; Wie, MB; Yoneda, Y	1
Campbell, J; Cataldo, AM; Chen, Y; Haroutunian, V; Jiang, Y; Mohan, PS; Nixon, RA; Paskevich, PA; Peterhoff, CM; Rao, MV; Schmidt, SD; Stavrides, PH; Yang, DS	1
Al-Sarraf, H; Krajci, D; Mohammadi, S; Pavlik, A	1
Kim, JH; Ong, WY	1
Armagan, G; Kanit, L; Sozmen, EY; Terek, CM; Yalcin, A	1
Hall, DG; Jordan, WH; Reams, RY; Sharma, AK; Snyder, PW	1
de la Villa, P; Gómez-Ramos, P; Pérez-Rico, C; Reinoso-Suárez, F	1
Burda, J; Burda, R; Danielisová, V; Domoráková, I; Gottlieb, M; Kravcuková, P; Mechírová, E; Némethová, M	1
Gohar, M; Humayun, S; Leystra-Lantz, C; McLean, J; Mepham, J; Moisse, K; Strong, MJ; Volkening, K	1
Brennan, J; Gao, Y; Gozen, O; Lepore, A; Li Jeon, N; Lorenzini, I; Poulsen, D; Robinson, MB; Rothstein, JD; Vidensky, S; Watkins, A; Won Park, J; Yang, Y	1
Bai, SS; Jin, DJ; Kong, QF; Li, HL; Sun, B; Wang, DD; Wang, GY; Wang, JH; Xiao, H; Xu, WS; Yan, BB; Zhai, DX	1
Farooqui, AA; He, X; Jenner, AM; Jittiwat, J; Kim, JH; Ong, WY; Patel, SC	1
Abdipranoto-Cowley, A; Croucher, D; Daniel, J; Galbraith, S; Henshall, S; Mervin, K; Park, JS; Vissel, B	1
Foote, LT; Kazl, C; Kim, MJ; Koh, S	1
Aroniadou-Anderjaska, V; Braga, MF; Figueiredo, TH; Fritsch, B; Qashu, F; Rogawski, MA	1
Beltramino, CA; Pereno, GL	1
Brunet, N; Calderó, J; Esquerda, JE; Tarabal, O	1
Chiang, AY; Jolly, RA; Jordan, WH; Reams, RY; Ryan, TP; Searfoss, GH; Sharma, AK; Snyder, PW	1
Miltiadous, P; Stamatakis, A; Stylianopoulou, F	1
Li, Z; Wang, W; Wang, X; Zhao, H; Zheng, H; Zhu, W	1
Berezin, V; Bock, E; Kiryushko, D; Korshunova, I; Pankratova, S; Sonn, K; Zharkovsky, A	1
Akamine, Y; Barinka, F; Esmaeili, MH; Lahtinen, L; Ndode-Ekane, XE; Pitkänen, A; Rantala, J	1
Andersson, DA; Rainey-Smith, SR; Rattray, M; Williams, RJ	1
Balaszczuk, V; Beltramino, CA; Pereno, GL	1
Kim, SU; Kim, YB; Lee, HJ; Lee, MC; Lim, IJ; Park, D; Ryu, JK	1
He, W; Hu, X; Wilson, CG; Wong, P; Xiong, W; Yan, R; Yang, J; Zhou, X	1
Duveau, V; Fritschy, JM	1
Borrelli, E; Bozzi, Y; Brilli, E; Santorufo, G; Tripathi, PP	1
Dalic, L; Dedeurwaerdere, S; Hicks, RJ; Liu, DS; Myers, DE; O'Brien, TJ; Tostevin, A; Vivash, L; Williams, DA	1
Holopainen, IE; Järvelä, JT; Kukko-Lukjanov, TK; Lopez-Picon, FR; Plysjuk, A; Ruohonen, S	1
Andrews, G; Chen, TT; Noebels, JL; Qian, J; Xu, K; Yoo, J	1
Martin, LJ	1
Auladell, C; Camins, A; de Lemos, L; Junyent, F; Pallàs, M; Porquet, D; Romero, R; Utrera, J	1
Ambrogini, P; Betti, M; Canonico, B; Ciuffoli, S; Colombo, E; Cuppini, R; Galli, F; Lattanzi, D; Minelli, A; Sestili, P; Viola, V	1
Koutsoudaki, PN; Miltiadous, P; Stamatakis, A; Stylianopoulou, F; Tiniakos, DG	1
Belluardo, N; Korhonen, L; Kukkonen, JP; Lindholm, D; Mudo, G; Putkonen, N; Putula, J	1
Domin, H; Dziubina, A; Gołembiowska, K; Kajta, M; Śmiałowska, M; Zięba, B	1
Dhanushkodi, A; McDonald, MP	1
Friedman, WJ; Le, AP	1
Raymick, J; Sarkar, S; Schmued, L	1
Drexel, M; Preidt, AP; Sperk, G	1
Goldowitz, D; Hamre, KM; Liu, L	1
Byun, JY; Kang, JW; Kim, DW; Lee, YH; Oh, SH; Seo, JH; Shin, YN; Yi, MH; Zhang, E	1
Fukui, M; Kang, KS; Wen, Y; Yamabe, N; Zhu, BT	1
Bloss, EB; El Maarouf, A; McCall, T; McEwen, BS; Nacher, J; Rutishauser, U; Weil, ZM	1
Ndode-Ekane, XE; Pitkänen, A	1
Cairns, NJ; Ferrario, M; Liberini, P; Moretto, G; Paterlini, M; Pizzi, M; Spano, P; Valerio, A	1
Doncarlos, LL; García-Ovejero, D; García-Segura, LM; Veiga, S	1
Guth, L; Inman, D; Steward, O	1
Lisý, V; Stastný, F	1
Giffard, RG; Glassford, A; Lee, JE; Xu, L	1
Hashimoto, K; Nakamura, R; Suzuki, Y; Takagi, Y; Umemura, K	1
Cespedes, GC; Cubeddu, LX; Guevara, BH	1
Cubeddu, LX; Guevara, BH; Hoffmann, IS; Torrico, F	1
Akbar, MT; Coffin, RS; de Belleroche, J; Kalwy, SA; Latchman, DS	1
Schauwecker, PE	3
Morimoto, K; Oda, T	1
Carvalho, AP; Carvalho, CM; Jakobsen, B; Malva, JO; Pinheiro, PS; Silva, AP; Zimmer, J	1
Brandt, C; Ebert, U; Löscher, W; Potschka, H	1
Angehagen, M; Ben-Menachem, E; Hansson, E; Rönnbäck, L	1
Bettler, B; Furtinger, S; Sperk, G	1
Chen, ZL; Indyk, JA; Strickland, S	1
Friedman, LK; Kaur, J; Liu, H; Magrys, BW; Velísková, J	1
Mahura, IS	1
Bartiromo, M; Bertolini, A; Ferrari, A; Genedani, S; Ottani, A; Renzo Botticelli, A; Saltini, S; Zaffe, D	1
Farooqui, AA; Fong, CW; Gopalakrishnakone, P; Hong, W; Ong, WY; Thwin, MM; Wei, S	1
Li, ST; Lu, YF; Matsui, H; Matsushita, M; Moriwaki, A; Oda, Y; Tomizawa, K; Wei, FY; Wu, HY	1
Hasegawa, M; Kurazono, S; Mori, S; Okamoto, M; Oohira, A; Sakiyama, J; Usui, S	1
Gilliams-Francis, KL; Naegele, JR; Quaye, AA	1
Aliprandi, M; Colella, D; De Simoni, MG; Moshé, SL; Perego, C; Ravizza, T; Richichi, C; Rizzi, M; Velískŏvá, J; Vezzani, A	1
Auyeung, WW; Lee, J; Mattson, MP	1
Sloviter, RS; Zappone, CA	1
Blot, B; Fraboulet, S; Hemming, FJ; Sadoul, R	1
Fukui, S; Ishihara, S; Nawashiro, H; Nomura, N; Otani, N; Shima, K; Tsuzuki, N	1
Gale, K; Kondratyev, A	2
Arsenijevic, D; Clavel, S; de Bilbao, F; Giannakopoulos, P; Julien, P; Murthy, MR; Paradis, E; Richard, D; Vallet, P	1
Gary, D; Mackenzie, A; Mattson, M; Robertson, GS; Thompson, C	1
Pérez-Clausell, J; Riba-Bosch, A	1
Shoham, S; Youdim, MB	1
Araki, T; Henshall, DC; Meller, R; Quan-Lan, J; Schindler, CK; Shinoda, S; Simon, RP; Taki, W	1
Dragunow, M; During, MJ; Francis, JS	1
Borges, K; Dingledine, R; McDermott, DL	1
Adamo, EB; Altavilla, D; Bellomo, M; Bitto, A; Bonaccorso, MC; Calapai, G; Laureanti, F; Marini, H; Marini, R; Minutoli, L; Passaniti, M; Seminara, P; Squadrito, F	1
Gides, JJ; Kalehua, AN; Kusiak, JW; Nagel, JE; Pyle, RS; Smith, RJ; Taub, DD; Whelchel, LM	1
Santos, JB; Schauwecker, PE; Williams, RW	1
Abdel-Rahman, A; Rao, MS; Shetty, AK	1
Chandrasekaran, A; Kaur, C; Ponnambalam, G	1
Brucklacher, R; Housman, C; Towfighi, J; Vannucci, RC	1
Aronoff, R; Maricq, AV; Mellem, JE; Seeburg, PH; Sprengel, R	1
Cho, J; Cho, SS; Jeon, GS; Kim, DW; Kim, SD; Lim, SY; Park, SW; Seo, JH	1
Adem, A; Chen, Z; Duan, RS; Mix, E; Nennesmo, I; Quezada, HC; Winblad, B; Zhu, J	1
Chen, Z; Concha, QH; Duan, RS; Ljunggren, HG; Mix, E; Winblad, B; Wu, Q; Zhu, J	1
Camins, A; Canudas, AM; Folch, J; Jiménez, A; Jordà, EG; Pallàs, M; Rimbau, V; Verdaguer, E	1
Noraberg, J	1
Akopian, G; Andersen, JK; Boonplueang, R; Kuhlenkamp, JF; Lu, SC; Stevenson, FF; Walsh, JP	1
Scallet, AC; Schmued, LC; Stowers, CC; Xu, L	1
Baráni, H; Halasová, E; Jakus, J; Poliacek, I; Stránsky, A; Szereda-Przestaszewska, M; Tomori, Z	1
Dahlström, A; Hansson, HA; Zhu, H	1
Alberch, J; Canals, JM; Canudas, AM; Pallàs, M; Pezzi, S	1
Gobbo, OL; O'Mara, SM	2
Löscher, W; Potschka, H; Volk, H	1
Bouquet, C; Karagogeos, D; Nothias, F; Soares, S; Traka, M; von Boxberg, Y	1
Ampo, K; Kadono, C; Kiryu-Seo, S; Kiyama, H; Konishi, H; Maeda, M; Ohba, N	1
Antal, K; Arabadzisz, D; Emri, Z; Fritschy, JM; Parpan, F	1
De Simoni, MG; Moshé, SL; Perego, C; Ravizza, T; Richichi, C; Rizzi, M; Velísková, J; Vezzani, A	1
Elger, B; Huth, A; Neuhaus, R; Ottow, E; Schneider, H; Seilheimer, B; Turski, L	1
Cole, AJ; Koh, S; Santos, TC	1
Bluthé, RM; Dantzer, R; Frenois, F; Kelley, KW	1
Nagayoshi, A; Oku, N; Takeda, A; Tamano, H; Yamada, K	1
Cano, J; Castaño, A; Machado, A; Revuelta, M; Venero, JL	1
Chechlacz, M; Gilliams-Francis, K; Lamonica, K; Lin, SL; Liu, J; Naegele, JR; Navarro-Quiroga, I; Neema, M	1
Kaur, G; Sharma, S	1
Lacaille, JC; Ratté, S	1
Heida, JG; Pittman, QJ; Teskey, GC	1
Benkovic, SA; Miller, DB; O'Callaghan, JP	1
Hattori, H; Matsuoka, O; Sakuma, S; Tokuhara, D; Yamano, T	1
Johnson, DA; Johnson, JA; Kan, YW; Kraft, AD; Lee, JM	1
McLin, JP; Steward, O	1
Brenner, M; Fukui, S; Gomi, H; Nawashiro, H; Ohsumi, A; Ooigawa, H; Otani, N; Shima, K; Toyooka, T	1
Farooqui, AA; Guan, XL; He, X; Ong, WY; Wenk, MR	1
Lin, AH; Luo, J; Masliah, E; Wyss-Coray, T	1
McLin, JP; Steward, O; Thompson, LM	1
Avanzini, G; Buzzi, A; Chikhladze, M; Franceschetti, S; Frassoni, C; Magnaghi, G; Paradiso, B; Sancini, G; Simonato, M; Zucchini, S	1
Lu, J; Roth, KA; Shacka, JJ; Uchiyama, Y; Xie, ZL; Zhang, J	1
Jandová, K; Langmeier, M; Milotová, M; Pokorný, J; Riljak, V	1
Chen, Z; Duan, RS; Mix, E; Quezada, HC; Winblad, B; Zhang, XM; Zhu, J	1
Jandová, K; Langmeier, M; Pokorný, J; Riljak, V	1
Aronica, E; Battaglia, G; Biagioni, F; Bruno, V; Busceti, CL; Caricasole, A; Fornai, F; Giorgi, FS; Gradini, R; Nicoletti, F; Riozzi, B; Storto, M	1
Gravanis, I; Parathath, SR; Tsirka, SE	1
Arias, C; Ferrera, P; Hernández-Ortega, K	1
Jandová, K; Langmeier, M; Riljak, V	1
Sanagi, T; Yabe, T; Yamada, H	1
B Jaffe, D; Chao, C; Dikkes, P; Guo, WH; Hemond, P; Lopez, MF; Yoon, K; Zurakowski, D	1
Ercan, F; Erkanli, G; Onat, F; Salik, E; San, T; Sirvanci, S; Yananli, HR	1
Carpentino, JE; Grabel, LB; Hartman, NW; Naegele, JR	1
Bellver-Estelles, C; Bonner, C; Hatazaki, S; Henshall, DC; Jimenez-Mateos, EM; Matsushima, S; Meller, R; Murphy, N; Prehn, JH; Simon, RP; Taki, W	1
Aono, S; Hayakawa, M; Ida, M; Kakizawa, H; Kojima, S; Kuroda, Y; Maeda, H; Matsui, F; Nakanishi, K; Oohira, A; Saito, A; Sato, Y; Tokita, Y	1
Akahoshi, N; Himi, T; Ishii, I; Ishizaki, Y; Murashima, YL	1
Bian, GL; Chen, LW; Wang, YQ; Wei, LC; Yung, KL	1
Araújo, IM; Bahr, BA; Brundin, P; Carreira, BP; Carvalho, CM; Gil, JM; Mohapel, P; Petersen, A; Pinheiro, PS; Soulet, D	1
Akashiba, H; Matsuki, N; Nakayama, K; Nakayama, KI; Nishiyama, N; Ueyama, C	1
Chae, JS; Kim, HC; Kim, HJ; Kim, WK; Ko, KH; Shin, EJ; Wie, MB; Yen, TP	1
Bing, G; Chae, JS; Jeong, JH; Jung, BD; Kim, HC; Kim, HJ; Kim, WK; Lee, SY; Park, ES; Shin, EJ; Wie, MB; Yen, TP	1
Einula, C; Gröhn, OH; Immonen, RJ; Kharatishvili, I; Pitkänen, A; Sierra, A	1
Duan, RS; Mohammed, AH; Winblad, B; Zhang, XM; Zhu, J; Zhu, SW	1
Miyamoto, R; Ogihara, T; Shimakawa, S; Suzuki, S; Tamai, H	1
Chai, M; Engblom, D; Lemberger, T; Parkitna, JR; Schütz, G	1
Geiger, JD; LaBella, FS; Nagy, JI	1
Moore, KE; Wuerthele, SM	1
Aamodt, A; Heggli, DE; Malthe-Sørenssen, D	1
Donaldson, PL; Duce, IR; Usherwood, PN	1
Baran, H; Hornykiewicz, O; Kish, SJ; Lassmann, H; Seitelberger, F; Sperk, G	1
McGeer, EG; McGeer, PL	1
Contestabile, A; Migani, P; Poli, A; Villani, L	1
Coyle, JT; Simonton, S; Zaczek, R	1
Artymyshyn, R; Goldberger, ME; Himes, BT; Murray, M; Tessler, A	1
Coull, BM; Woodward, WR	1
Kleinschmidt, J; Yazulla, S	1
Meldrum, BS; Menini, C; Riche, D; Silva-Comte, C; Stutzmann, JM	1
Bird, SJ; Gulley, RL; Mattox, DE; Ulrich, FA	1
Cuthbertson, GJ; Evenson, DA; Nadler, JV	1
Lancaster, B; Wheal, HV	1
Divac, I; Krivokuća, Z; Milivojević, Z	1
Schwarcz, R; Whetsell, WO	1
Krammer, EB	1
Francis, A; Rivett, AJ; Roth, JA; Whittemore, R	1
Bolz, J; Peichl, L	1
Czuczwar, S; Kleinrok, Z; Milart, P; Turski, W	1
Köhler, C; Schwarcz, R	1
Ibata, Y; Murabe, Y; Sano, Y	1
Cotman, CW; Gentry, C; Nadler, JV; Perry, BW	2
Ibata, Y; Kinoshita, H; Kubo, S; Murabe, Y; Obata, HL	1
Handelmann, GE; Olton, DS	1
Panula, PA	1
Iwatsubo, K; Kondo, Y	1
Cotman, CW; Nadler, JV; Perry, BW	1
Cuenod, M; Stella, M; Streit, P	1
Kurihara, E; Kuriyama, K; Yoneda, Y	1
Smiałowski, A	1
Bindokas, VP; Miller, RJ	1
Ishida, M; Kataoka, K; Mitani, A; Nakamura, Y; Ogata, T; Shibata, T; Shinozaki, H; Tsuji, K	1
Brown, CS; Chen, Q; Harris, C; Howe, A; Reiner, A; Surmeier, DJ	1
Bell, MD; Perry, VH	1
Anderton, BH; Leigh, PN; Meldrum, BS; Nunn, PB; Willis, CL	1
Choi, DW; Turetsky, D; Weiss, JH; Wilke, G	1
Massieu, L; Tapia, R	2
Albert, A; Bonhomme, V; Collette, J; Hans, P; Moonen, G	1
Cuevas, P; Giménez-Gallego, G; Herreras, O; Largo, C; Revilla, C	1
Britto, LR; Duvoisin, RM; Hamassaki-Britto, DE; Zhang, C	1
Rothwell, NJ; Strijbos, PJ	1
Lu, YM; Weiss, JH; Yin, HZ	1
Amaral, DG; Gualandris, A; Strickland, S; Tsirka, SE	1
Canzoniero, LM; Choi, DW; Csernansky, C; Demaro, J; Gwag, BJ; Koh, JY; Sensi, SL; Wie, MB	1
Domagala, W; Filipkowski, RK; Hetman, M; Kaczmarek, L	1
Brines, ML; Dare, AO; de Lanerolle, NC	1
Freund, TF; Maglóczky, Z	2
Fagg, GE; Massieu, L; McVey, M; Thedinga, KH	1
Iannotti, F; Sundström, LE; Wilde, GJ	1
Massieu, L; Morales-Villagrán, A; Tapia, R	1
Bennett, SA; Roberts, DC; Staines, WA; Stevenson, B	1
Chinnery, RM; Ince, PG; Shaw, PJ	1
Shinozaki, H	1
Ciani, E; Contestabile, A; Facchinetti, F; Virgili, M	1
Ben-Ari, Y; Jorquera, I; Niquet, J; Represa, A	1
Keilhoff, G; Wolf, G	1
Macgregor, DG; Stone, TW	1
Finch, RE; Peng, YG; Ramsdell, JS; Switzer, RC; Taylor, TB	1
Duberley, RM; Ham, J; Rickards, CR; Scanlon, MF	1
Akiyama, H; Ikeda, K; Kimura, H; Kondo, H; McGeer, EG; McGeer, PL; Tooyama, I	1
Jarrard, LE; Meldrum, BS	1
Baudry, M; Najm, I; Schreiber, SS; Tocco, G	1
Binienda, Z; Caputo, FA; Hall, S; Paule, MG; Rountree, RL; Scallet, AC; Schmued, L; Slikker, W; Sobotka, T	1
Frey, P; García-Ladona, FJ; Mengod, G; Palacios, JM; Probst, A; Solà, C	1
Diemer, NH; Finsen, BR; Jørgensen, MB; Zimmer, J	1
Olney, JW; Price, MT; Yamada, KA; Zorumski, CF	1
Best, N; Mitchell, J; Sundstrom, LE; Wheal, HV	1
Friedberg, EB; Ross, DT	1
Baker, SJ; Curran, T; Hayward, M; Miao, GG; Morgan, JI; Robertson, LM; Schilling, K; Smeyne, RJ; Vendrell, M	1
Borsello, T; Rossi, F; Strata, P; Vaudano, E	1
Finch, CE; Morgan, TE; Nichols, NR; Pasinetti, GM	1
Comelli, MC; Cosi, C; Guidolin, D; Skaper, SD; Spoerri, PE	1
Bardgett, ME; Csernansky, JG; Jackson, JL; Taylor, GT	1
Scallet, AC; Schmued, LC; Slikker, W	1
Halonen, T; Kotti, T; Miettinen, R; Riekkinen, PJ; Toppinen, A; Tuunanen, J	1
Matyja, E; Renkawek, K	1
Bendotti, C; Boschert, U; Catsicas, S; Dickinson, R; O'Shaughnessy, C; Pich, EM; Tessari, M	1
Bing, G; Chen, J; Hong, JS; McMillian, MK; Pennypacker, KR; Pérez-Otano, I	1
Weiss, JH; Yin, HZ	1
Chiang, J; Lu, YM; Weiss, JH; Yin, HZ	1
Benabid, AL; Benazzouz, A; Piallat, B	1
Eckersdorf, B; Golebiewski, H; Konopacki, J	1
Massieu, L; Tapia, R; Velasco, I	1
Graham, DI; Jones, PA; MacGregor, DG; Maxwell, WL; Stone, TW	1
Jöhren, O; Saavedra, JM; Viswanathan, M	1
Kwak, S; Nakamura, R	1
Niquet, J; Represa, A	1
Lei, DL; Liu, HM; Yang, DL	1
Coyle, JT; Getz, RL; Konradi, C; Leveque, JC; Simonian, NA	1
Deupree, DL; Dickman, E; Kirch, RD; Schloss, JV; Tang, XW; Wu, JY; Yarom, M	1
Kamada, T; Kitagawa, K; Kuwabara, K; Mabuchi, T; Mandai, K; Matsumoto, M; Matsushita, K; Ogawa, S; Ohtsuki, T; Tagaya, M; Ueda, H; Yanagihara, T	1
Rogove, AD; Strickland, S; Tsirka, SE	1
Marsala, M; Yaksh, TL; Yang, LC	1
Ciani, E; Contestabile, A; Virgili, M	1
Baudry, M; DeSimoni, MG; Finch, CE; Mascarucci, P; Musleh, WD; Pasinetti, GM; Sakhi, S; Schreiber, S; Tocco, G	1
Bugge, TH; Degen, JL; Rogove, AD; Strickland, S; Tsirka, SE	1
Albertson, C; Schmued, LC; Slikker, W	1
Martin, LJ; Portera-Cailliau, C; Price, DL	1
Abraham, CR; Mallory, M; Masliah, E; Mucke, L; Rockenstein, EM; Sheldon, E; Veinberg, I; Westland, CE	1
Garcia, ML; Garcia, VB; Isackson, PJ; Murray, KD; Strehler, EE	1
Buckmaster, PS; Dudek, FE	1
Aisen, PS; Freire-Moar, J; Pasinetti, GM; Sakhi, SH; Schreiber, SS; Tocco, G	1
Fuchs, K; Schwarzer, C; Sieghart, W; Sperk, G; Tsunashima, K; Wanzenböck, C	1
Chabot, JG; Doré, S; Kar, S; Quirion, R; Seto, D	1
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Babb, TL; Cifuentes, F; Mathern, GW; Pretorius, JK	1
Aronica, EM; Bennett, MV; Gorter, JA; Grooms, SY; Paupard, MC; Zukin, RS	1
Scallet, AC; Ye, X	1
Rogove, AD; Tsirka, SE	1
Carriedo, SG; Ha, DH; Weiss, JH; Yin, HZ	1
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Hefti, F; Venero, JL	1
Bywood, PT; Johnson, SM	3
Andrew, RD; Jarvis, CR; Polischuk, TM	1
Chen, Y; Kirsch, J; Maerz, W; Mitchell, J; Schachner, M; Van Rossum, D; Wheal, HV; Wieland, H	1
Kitamura, Y; Matsuoka, Y; Taniguchi, T	1
Friedman, LK	1
Bardgett, ME; Csernansky, CA; Csernansky, JG; Kogelman, L; Montgomery, EM	1
Fosbraey, P; Kitchen, I; Ridd, MJ	1
Damm, D; Mark, RJ; Mattson, MP; Opanashuk, LA; Porter, J; Seroogy, KB	1
Bolton, SJ; Perry, VH	1
Baudry, M; Liu, W; Rong, Y; Schreiber, SS	1
Kitamura, Y; Matsuoka, Y; Okazaki, M; Taniguchi, T; Terai, K	1
Chen, ST; Chuang, JI	1
Kristensen, BW; Noraberg, J; Zimmer, J	1
Ben-Ari, Y; Guischard, F; Khrestchatisky, M; Ouaghi, P; Rivera, S; Timsit, S; Tremblay, E	1
Gwag, BJ; Joe, E; Kim, EY; Kim, YH; Koh, JY; Sohn, S	1
Bar-Peled, O; Knudson, M; Korsmeyer, SJ; Rothstein, JD	1
Lim, TM; Makjanić, J; Ong, WY; Ren, MQ; Watt, F	1
Endo, A; Nagai, N; Takada, A; Takada, Y; Takahashi, H; Urano, T	1
Carricondo, F; Gil-Loyzaga, P; Hernández, E; Poch-Broto, J; Simón, F	1
Biasiol, S; Jhaveri, S; Repici, M; Vercelli, A	1
Ginsberg, SD; Martin, LJ; Portera-Cailliau, C	1
Gerard, C; Höepken, UE; Lu, B; McGinty, A; Osaka, H; Pasinetti, GM	1
Duan, W; Mattson, MP; Rangnekar, VM	1
Bing, G; Chang, RC; Feng, Z; Hong, JS; Hudson, P; Jin, L; Tiao, N	1
Akeefe, H; Bellosta, S; Buttini, M; Mahley, RW; Mucke, L; Orth, M; Pitas, RE; Wyss-Coray, T	1
Conti, M; De Luigi, A; De Simoni, MG; Marchesi, F; Moneta, D; Ravizza, T; Vezzani, A	1
Kimura, H; Kitamura, Y; Matsuoka, Y; Okazaki, M; Takata, K; Taniguchi, T; Tooyama, I	1
Bol, JG; Eriksson, C; Lucassen, PJ; Schultzberg, M; Van Dam, AM; Winblad, B	1
Chen, Q; Reiner, A; Surmeier, DJ	1
Iannotti, F; Pringle, AK; Signorelli, F; Thomas, SJ	1
Bugge, TH; Chen, ZL; Degen, JL; Indyk, JA; Kombrinck, KW; Strickland, S	1
Kitamura, Y; Matsuoka, Y; Ohta, S; Okazaki, M; Sekino, Y; Takata, K; Taniguchi, T	1
Emerson, MR; Nelson, SR; Pazdernik, TL; Samson, FE	1
Blondeau, N; Heurteaux, C; Lazdunski, M; Plamondon, H	1
Choi, I; Gwag, BJ; Huh, K; Jung, NP; Kim, EY; Ko, HW; Oh, YK; Park, EC; Shin, HC; Won, SJ	1
Brorson, JR; Robberecht, W; Vandenberghe, W	1
Kim, J; Kim, YC; Lee, MK; Markelonis, GJ; Oh, TH; Yeo, H	1
Bouilleret, V; Boyet, S; Marescaux, C; Nehlig, A	1
Ramirez, JJ; Schauwecker, PE; Steward, O	1
Bendotti, C; Guglielmetti, F; Hirst, WD; Samanin, R; Tortarolo, M	1
Jolkkonen, J; Pitkänen, A	1
Benarese, M; Boroni, F; Goffi, F; Pizzi, M; Spano, PF; Valerio, A	1
Han, SH; Lee, KW; Lee, SH	1
Baldessarini, RJ; Tarazi, FI	1
Eriksson, C; Iverfeldt, K; Schultzberg, M; Tehranian, R; Winblad, B	1
Andrews, AM; Binienda, Z; Scallet, AC; Schmued, LC; Slikker, W; Wang, GJ	1
Hopkins, KJ; Schmued, LC; Wang, G	1
Borin, G; Ceccon, M; Facci, L; Floreani, M; Giusti, P; Imbesi, M; Skaper, SD	1
Bouilleret, V; Marescaux, C; Namer, IJ; Nehlig, A	1
de Kloet, ER; Grootendorst, J; Haasdijk, E; Jaarsma, D; Mulder, M	1
Azcoitia, I; Fernandez-Galaz, C; Garcia-Segura, LM; Sierra, A	1
Ajilore, O; Bliss, T; Sapolsky, R; Yusim, A	1
Doi, K; Fujii, K; Fuse, Y; Hasegawa, T; Kubo, T; Nishimura, H; Uno, Y	1
Carrasco, J; Hadberg, H; Hidalgo, J; Molinero, A; Penkowa, M	1
Hopkins, KJ; Schmued, LC	1
Dumas, TC; Ho, DY; Lawrence, MS; McLaughlin, JR; Sapolsky, RM	1
Baráni, H; Bosel'ová, L; Jakus, J; Poliacek, I; Stránsky, A	1
Hirai, H; Kurokawa, K; Matsuda, M; Onteniente, B; Riban, V; Suzuki, F	1
Brusa, R; Casarini, M; Diodato, E; Grilli, M; Lozza, G; Memo, M; Ongini, E; Rozmahel, R; St George-Hyslop, P; Uberti, D; Westaway, D	1
Ahlenius, S; Eriksson, C; Schultzberg, M; Winblad, B; Zou, LP	1
Lees, GJ; Leong, W	1
Asaga, H; Ishigami, A	1
Belluardo, N; Korhonen, L; Lindholm, D	1
Carrasco, J; Hidalgo, J; Molinero, A; Penkowa, M	1
Auvergne, R; Brana, C; El Bahh, B; Le Gal La Salle, G; Leré, C; Rougier, A	1
O'Neill, MJ	1
He, XP; Shiosaka, S; Yoshida, S	1
Bonhomme, N; Casara, P; Dorey, G; Lestage, P; Lockhart, B; Roger, A	1
Akaike, A; Ishida, Y; Kakimura, J; Kitamura, Y; Mizutani, H; Shimohama, S; Takata, K; Taniguchi, T	1
Bagnis, C; Cisterni, C; Jordier, F; Kallenbach, S; Pettmann, B	1
Corti, C; Ferraguti, F; Mion, S; Valerio, E; Xuereb, J	1
Bienemann, A; Henley, JM; Ma, J; Noel, J; Ralph, GS; Tan, HK; Uney, JB	1
Azcoitia, I; Garcia-Segura, LM; Harada, N; Honda , S; Sierra, A; Veiga, S	1
Lu, XR; Ong, WY	1
Shetty, AK; Turner, DA	1
Leung, LS; Wu, K	1
Levid, J; Schreiber, SS; Tan, Z	1
Baik, EJ; Kim, EJ; Kwon, KJ; Lee, JE; Lee, SH; Moon, CH	1
Gale, K; Kondratyev, A; Sahibzada, N	1
Schreiber, SS; Tan, Z; Tu, W	1
Benz, AM; Izumi, M; Izumi, Y; Zorumski, CF	1
Bottazzi, B; Garlanda, C; Hirsch, E; Mantovani, A; Moneta, D; Peri, G; Ravizza, T; Richards, GJ; Vezzani, A	1
Kiessling, M; Roth, SU; Sommer, C	1
Du, F; Eid, T; Schwarcz, R	1
Hashizume, K; Sawamura, A; Tanaka, T; Yoshida, K	1
Kargieman, L; Kasanetz, F; Murer, MG; Pazo, JH; Riquelme, LA; Tseng, KY	1
Chow, D; Einheber, S; Milner, TA; Pierce, JP; Schnapp, LM; Znamensky, V	1
Dettbarn, WD; Gupta, RC; Milatovic, D; Zivin, M	1
Day, BJ; Li, QY; Patel, M; Pedersen, C	1
Che, Y; Han, PL; Lee, JK; Piao, CS	1
Ananth, C; Gopalakrishnakone, P; Kaur, C; Thameem Dheen, S	1
Baudry, M; Bi, R; Chun, JT; Hoe, W; Liu, R; Liu, W; Schreiber, SS	1
Baldinotti, I; Ciani, E; Contestabile, A	1
Kim, HJ; Kim, SP; Lee, SR; Moon, KD; Oh, SY	1
Brooke, SM; McGaugh, JL; Phillips, RG; Power, AE; Roozendaal, B; Sapolsky, RM	1
Chen, L; Li, S; Liu, Z; Tian, Z; Wang, Y	1
Shetty, AK; Zaman, V	1
Berman, FW; LePage, KT; Murray, TF	1
Chabot, JG; Mennicken, F; Quirion, R	1
Ayala-Guerrero, F; Gonzalez-Maciel, A; Reynoso-Robles, R; Romero-Velazquez, RM; Vargas, L	1
Borrelli, E; Bozzi, Y	1
Choi, YH; Jang, YP; Kim, J; Kim, SG; Kim, SR; Kim, YC; Markelonis, GJ; Oh, TH	1
Bulloch, K; de Leon, MJ; Dyakin, V; McEwen, BS; Patel, A; Vadasz, C; Wolf, OT	1
Fritschy, JM; Grady, RM; Knuesel, I; Riban, V; Sanes, JR; Schaub, MC; Zuellig, RA	1
Akiyama, K; Asaga, H; Ishigami, A; Ohsawa, T	1
Hashizume, K; Sawamura, A; Tanaka, T	1
Holmes, GL; Stafstrom, CE; Tandon, P; Yang, Y	1
Lu, W; Rogove, AD; Tsirka, SE	1
Coyle, JT; Schwarcz, R; Zaczek, R	1
Bird, SJ; Fex, J; Gulley, RL; Wenthold, RJ	1
Coyle, JT	2
Di Chiara, G; Gessa, GL; Morelli, M; Mulas, ML; Porceddu, ML	1
Fuxe, K; Goldstein, M; Hökfelt, T; Jonsson, G; Schwarcz, R; Terenius, L	1
Cuénod, M; Henke, H; Reubi, JC; Streit, P	1
Gottesfeld, Z; Jacobowitz, DM	1
McGeer, EG; McGeer, PL; Singh, K	1
Bennett, JP; Coyle, JT; Schwarcz, R	1
de Gubareff, T; Olney, JW	1
Dray, F; Gros, C; Llorens, C; Pollard, H; Schwartz, JC	1
Coyle, JT; Hedreen, JC; Zaczek, R	1
Ben-Ari, Y; Naquet, R; Ottersen, OP; Tremblay, E	1
Ben-Ari, Y; Lagowska, J; Le Gal La Salle, G; Tremblay, E	1
Glendenning, KK; Hutson, KA; Masterton, RB	1
Fuxe, K; Köhler, C; Schwarcz, R	1
Karobath, M; Krammer, EB; Lischka, MF; Schönbeck, G	1
Altar, CA; Christakos, S; German, D; Iacopino, A; Sonsalla, PK	1
Coyle, JT; Lyons, WE; Puttfarcken, PS	1
Isacson, O; Sofroniew, MV	1
Cavazos, J; Golarai, G; Sutula, T	1
Chan, YG; Kaur, C; Ling, EA	1
Kaur, C; Ling, EA	1
Borgers, M; Van Deuren, B; Van Reempts, J	1
Jope, RS; Kolasa, K; Li, X; Song, L	1
Haruhiko, S; Hitoshi, A; Michiko, I; Shin, K	1
Hertzberg, EL; Nagy, JI; Vukelic, JI; Yamamoto, T	1
Cotman, CW; Koh, JY; Lin, A; Palmer, E	1
Kollegger, H; McBean, GJ; Tipton, KF	1
Olney, JW; Pathikonda, M; Snider, WD; Stewart, GR	1
Hugon, J; Vallat, JM	1
Andersson, PB; Gordon, S; Perry, VH	1
Memo, M; Pizzi, M; Ribola, M; Spano, P; Valerio, A	1
Pearson, HE; Sonstein, WJ; Stoffler, DJ	2
Matthews, JC; Scallet, AC	1
Murer, MG; Pazo, JH; Riquelme, LA; Stern, J	1
Chai, CY; Lin, AM; Pan, CM; Wang, SD	1
Arvin, B; Le Peillet, E; Meldrum, BS; Moncada, C	1
Abicht, K; Fischer, S; Hass, P; Keilhoff, G; Wolf, G	1
Leander, JD; Ornstein, PL; Salhoff, CR; Schoepp, DD	1
D'Incalci, M; Ignatowicz, E; Rizzi, M; Vezzani, AM	1
Ahier, RG; Cremer, JE; Doran, M; Hajnal, JV; King, MD; van Bruggen, N; Williams, SR	1
Ford, LM; Giordano, M; Sanberg, PR; Shipley, MT	1
Baimbridge, KG; Choi, DW; Koh, J; Weiss, JH	1
Coyle, JT; Miyamoto, M	1
Ebner, FF; Ross, DT	1
Benavides, J; Capdeville, C; Dauphin, F; Dubois, A; Duverger, D; Fage, D; Gotti, B; MacKenzie, ET; Scatton, B	1
Chung, SK; Cohen, RS; Pfaff, DW	1
Bernardi, G; Calabresi, P; De Murtas, M; Mercuri, NB	1
Beart, PM; Jarrott, B; Lewis, SJ; Louis, CJ; Louis, WJ; Verberne, AJ	1
Carey, RG; Horn, KM	1
Mizuno, N; Sugimoto, T	1
Hinrichsen, CF; Ryan, AT	1
Frederickson, CJ; Hernandez, MD; McGinty, JF	1
Barthe, D; Hugon, J; Leboutet, MJ; Spencer, PS; Vallat, JM	1
Arissian, K; Asanuma, H; Ichikawa, M	1
Olney, JW	1
Choi, DW; Kriegstein, AR; Maulucci-Gedde, M	1
Morgan, IG	1
Benavides, J; Carter, C; Fage, D; Scatton, B	1
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Foster, AC; Gill, R; Woodruff, GN	1
Marasigan, SM; Miyoshi, K; Sato, M	1
Sangalli, L; Schwarcz, R; Vezzani, A; Wu, HQ	1
Meldrum, B	1
Gramsbergen, JB; Korf, J; Loopuijt, L; Paans, AM; Vaalburg, W; Veenma-van der Duin, L	1
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Foster, AC; Gill, R; Kemp, JA; Woodruff, GN	1
Nadler, JV; Sater, RA	1
Deckel, AW; DiFiglia, M; Schiff, L	1
Besson, JM; Peschanski, M	1
Horsburgh, GM; Sefton, AJ	1
Matyja, E	1
Carpenter, P; Dreher, B; Lim, WL; Sefton, AJ	1
Armstrong, DR; Ault, B; Gruenthal, M; Nadler, JV; Okazaki, MM	1
Murakami, TH; Ozaki, HS; Shimada, M; Toyoshima, T	1

Reviews

12 review(s) available for kainic acid and Nerve Degeneration

Article	Year
Role of JNK isoforms in the kainic acid experimental model of epilepsy and neurodegeneration. Frontiers in bioscience (Landmark edition), 2017, 01-01, Volume: 22, Issue:5 Topics: Adaptor Proteins, Signal Transducing; Animals; Anticonvulsants; Disease Models, Animal; Epilepsy; Hippocampus; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Kainic Acid; MAP Kinase Signaling System; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 10; Nerve Degeneration	2017
[Cerebral ischemia-hypoxia and biophysical mechanisms of neurodegeneration and neuroprotection effects]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2003, Volume: 49, Issue:2 Topics: Animals; Brain Ischemia; Calcium; Calcium Channels; Excitatory Amino Acid Antagonists; Humans; Hypoxia, Brain; Ion Channels; Kainic Acid; Nerve Degeneration; Neurons; Neuroprotective Agents; Oxygen; Reactive Oxygen Species; Receptors, Glutamate; Reperfusion Injury; Sodium; Sodium Channel Blockers; Sodium Channels	2003
Domoic acid-induced neurotoxicity in the hippocampus of adult rats. Neurotoxicity research, 2004, Volume: 6, Issue:2 Topics: Animals; Bivalvia; Hippocampus; Humans; Kainic Acid; Nerve Degeneration; Neurotoxins; Rats; Shellfish	2004
Selective degeneration and synaptic reorganization of hippocampal interneurons in a chronic model of temporal lobe epilepsy. Advances in neurology, 2006, Volume: 97 Topics: Afferent Pathways; Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Interneurons; Kainic Acid; Nerve Degeneration; Nerve Net; Neural Inhibition; Pyramidal Cells; Synapses	2006
[Kainic acid and neurobiology]. Ceskoslovenska fysiologie, 2006, Volume: 55, Issue:3 Topics: Animals; Brain; Excitatory Amino Acid Agonists; Humans; Kainic Acid; Nerve Degeneration; Receptors, Kainic Acid	2006
Recent advances in the use of selective neuron-destroying agents for neurobiological research. Experientia, 1984, Jun-15, Volume: 40, Issue:6 Topics: Animals; Aziridines; Choline; Colchicine; Folic Acid; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Lectins; Mitogens; Mustard Compounds; Nerve Degeneration; Nervous System; Neurons; Piperidines; Pyrrolidonecarboxylic Acid; Quinolinic Acid; Quinolinic Acids	1984
Excitotoxic mechanisms of neurodegeneration in transmissible spongiform encephalopathies. Annals of the New York Academy of Sciences, 1997, Oct-15, Volume: 825 Topics: Animals; Brain; Cricetinae; Glutamic Acid; Humans; Hypothalamus; Ibogaine; Kainic Acid; Mice; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Prion Diseases	1997
Kainate-evoked modulation of gene expression in rat brain. Acta biochimica Polonica, 1997, Volume: 44, Issue:4 Topics: Animals; Brain; Dystrophin; Excitatory Amino Acids; Gene Expression; Kainic Acid; Models, Neurological; Nerve Degeneration; Rats; Receptors, Glutamate; RNA, Messenger; Seizures; Transcription Factors	1997
Molecular mechanisms that underlie structural and functional changes at the postsynaptic membrane during synaptic plasticity. Progress in neurobiology, 1998, Volume: 55, Issue:6 Topics: Animals; Hippocampus; Humans; Kainic Acid; Multigene Family; Nerve Degeneration; Neural Cell Adhesion Molecules; Neuronal Plasticity; Receptors, LDL; Synaptic Membranes	1998
Regional localization of dopamine and ionotropic glutamate receptor subtypes in striatolimbic brain regions. Journal of neuroscience research, 1999, Feb-15, Volume: 55, Issue:4 Topics: Animals; Binding Sites; Frontal Lobe; Hippocampus; Kainic Acid; Limbic System; Neostriatum; Nerve Degeneration; Nucleus Accumbens; Prosencephalon; Rats; Receptors, Dopamine; Receptors, Glutamate; Visual Cortex	1999
Excitatory transmitters and epilepsy-related brain damage. International review of neurobiology, 1985, Volume: 27 Topics: Acetylcholine; Amygdala; Animals; Brain; Cholinesterase Inhibitors; Convulsants; Electric Stimulation; Epilepsy; Kainic Acid; Lithium; Nerve Degeneration; Neural Pathways; Neurons; Neurotransmitter Agents; Piperidines; Rats; Somatosensory Cortex; Synaptic Transmission	1985
Kainic acid: insights into excitatory mechanisms causing selective neuronal degeneration. Ciba Foundation symposium, 1987, Volume: 126 Topics: Animals; Biomechanical Phenomena; Brain; Injections; Kainic Acid; Nerve Degeneration; Nervous System; Nervous System Physiological Phenomena; Neurons; Receptors, Kainic Acid; Receptors, Neurotransmitter	1987

Other Studies

481 other study(ies) available for kainic acid and Nerve Degeneration

Article	Year
Fatherhood diminishes the hippocampal damaging action of excitotoxic lesioning in mice. Journal of neuroendocrinology, 2019, Volume: 31, Issue:10 Topics: Animals; Female; Gliosis; Hippocampus; Infusions, Intraventricular; Kainic Acid; Male; Mice; Nerve Degeneration; Nesting Behavior; Paternity; Phosphorylation; Prolactin; Proto-Oncogene Proteins c-akt; Receptors, Prolactin; STAT5 Transcription Factor	2019
Microtubule-dependent processes precede pathological calcium influx in excitotoxin-induced axon degeneration. Journal of neurochemistry, 2020, Volume: 152, Issue:5 Topics: Animals; Axons; Calcium; Cells, Cultured; Excitatory Amino Acid Agonists; Kainic Acid; Mice; Mice, Inbred C57BL; Microtubules; Nerve Degeneration	2020
Hyperoside alleviates epilepsy-induced neuronal damage by enhancing antioxidant levels and reducing autophagy. Journal of ethnopharmacology, 2020, Jul-15, Volume: 257 Topics: Animals; Antioxidants; Autophagosomes; Autophagy; Autophagy-Related Proteins; CA3 Region, Hippocampal; Disease Models, Animal; DNA-Binding Proteins; Kainic Acid; Male; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Quercetin; Seizures; Signal Transduction	2020
Remarkable migration propensity of dental pulp stem cells towards neurodegenerative milieu: An in vitro analysis. Neurotoxicology, 2020, Volume: 81 Topics: Animals; Cells, Cultured; Chemotaxis; Coculture Techniques; Culture Media, Conditioned; Dental Pulp; Hippocampus; Humans; Kainic Acid; Mesenchymal Stem Cells; Mice; Nerve Degeneration; Paracrine Communication; Phenotype; Stem Cells	2020
Kainate-Induced Degeneration of Hippocampal Neurons. Protective Effect of Activation of the Endocannabinoid System. Bulletin of experimental biology and medicine, 2021, Volume: 171, Issue:3 Topics: Animals; Arachidonic Acids; Autophagosomes; Benzamides; CA3 Region, Hippocampal; Carbamates; Dentate Gyrus; Endocannabinoids; Endoplasmic Reticulum; Excitatory Amino Acid Agonists; Golgi Apparatus; Kainic Acid; Lysosomes; Male; Microscopy, Electron; Necrosis; Nerve Degeneration; Polyunsaturated Alkamides; Pyramidal Cells; Rats; Rats, Wistar; Status Epilepticus	2021
The role of rosemary extract in degeneration of hippocampal neurons induced by kainic acid in the rat: A behavioral and histochemical approach. Journal of integrative neuroscience, 2018, Volume: 17, Issue:1 Topics: Animals; Avoidance Learning; Disease Models, Animal; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Fluoresceins; Hippocampus; Kainic Acid; Learning Disabilities; Male; Maze Learning; Memory Disorders; Nerve Degeneration; Neurons; Neuroprotective Agents; Plant Extracts; Rats; Rats, Wistar; Rosmarinus; Time Factors	2018
Developmental and sex differences in tetramethylenedisulfotetramine (TMDT)-induced syndrome in rats. Developmental neurobiology, 2018, Volume: 78, Issue:4 Topics: Animals; Brain; Bridged-Ring Compounds; Cell Death; Dose-Response Relationship, Drug; Electroencephalography; Female; Kainic Acid; Male; Nerve Degeneration; Neurons; Neurotoxicity Syndromes; Random Allocation; Rats, Sprague-Dawley; Seizures; Sex Characteristics	2018
Neurobiological Correlates of Alpha-Tocopherol Antiepileptogenic Effects and MicroRNA Expression Modulation in a Rat Model of Kainate-Induced Seizures. Molecular neurobiology, 2018, Volume: 55, Issue:10 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; alpha-Tocopherol; Animals; Blood-Brain Barrier; Disease Models, Animal; Gene Expression Regulation; Inflammation; Kainic Acid; Male; MicroRNAs; Nerve Degeneration; Oocytes; Oxidative Stress; Rats, Sprague-Dawley; Receptors, GABA; Seizures; Status Epilepticus; Xenopus	2018
Reactivity of microglia and astrocytes after an excitotoxic injury induced by kainic acid in the rat spinal cord. Tissue & cell, 2019, Volume: 56 Topics: Animals; Antibodies, Anti-Idiotypic; Apoptosis; Astrocytes; Glial Fibrillary Acidic Protein; Kainic Acid; Microglia; Nerve Degeneration; Neuroglia; Neurons; Rats; Spinal Cord; Spinal Cord Injuries	2019
Lipid markers and related transcripts during excitotoxic neurodegeneration in kainate-treated mice. The European journal of neuroscience, 2019, Volume: 50, Issue:1 Topics: Animals; Biomarkers; CA1 Region, Hippocampal; Cell Death; Cell Proliferation; Cholesterol; Gene Expression Profiling; Kainic Acid; Lipid Droplets; Male; Membrane Lipids; Mice; Mice, Inbred C57BL; Microglia; Microscopy, Electron; Microscopy, Fluorescence, Multiphoton; Nerve Degeneration; Neurons; Up-Regulation	2019
Subventricular zone-derived neural stem cell grafts protect against hippocampal degeneration and restore cognitive function in the mouse following intrahippocampal kainic acid administration. Stem cells translational medicine, 2013, Volume: 2, Issue:3 Topics: Animals; Astrocytes; Behavior, Animal; Cell Movement; Cell Proliferation; Cell Survival; Cognition; Disease Models, Animal; Epilepsy, Temporal Lobe; Genetic Therapy; Genetic Vectors; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Insulin-Like Growth Factor I; Kainic Acid; Lentivirus; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Degeneration; Neural Stem Cells; Neurogenesis; Neurons; Spheroids, Cellular; Time Factors; Transduction, Genetic	2013
Epilepsy-induced motility of differentiated neurons. Cerebral cortex (New York, N.Y. : 1991), 2014, Volume: 24, Issue:8 Topics: Animals; Cell Adhesion Molecules, Neuronal; Cell Body; Cell Movement; Dendrites; Disease Models, Animal; Epilepsy; Extracellular Matrix Proteins; Green Fluorescent Proteins; Immunohistochemistry; In Situ Hybridization; Interneurons; Kainic Acid; Male; Mice, Inbred C57BL; Mice, Transgenic; Nerve Degeneration; Nerve Tissue Proteins; Neurogenesis; Neurons; Patch-Clamp Techniques; Reelin Protein; RNA, Messenger; Serine Endopeptidases; Tissue Culture Techniques	2014
Excitotoxicity-induced immediate surge in hippocampal prostanoid production has latent effects that promote chronic progressive neuronal death. Prostaglandins, leukotrienes, and essential fatty acids, 2013, Volume: 88, Issue:5 Topics: Animals; Cell Death; Hippocampus; Kainic Acid; Male; Microglia; Nerve Degeneration; Neurons; Prostaglandins; Rats; Rats, Wistar	2013
Kainate-induced calcium overload of cortical neurons in vitro: Dependence on expression of AMPAR GluA2-subunit and down-regulation by subnanomolar ouabain. Cell calcium, 2013, Volume: 54, Issue:2 Topics: Adamantane; Animals; Calcium; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Female; In Vitro Techniques; Kainic Acid; Nerve Degeneration; Neurons; Ouabain; Patch-Clamp Techniques; Piperidines; Pregnancy; Rats; Rats, Wistar; Receptors, AMPA	2013
Bupropion attenuates kainic acid-induced seizures and neuronal cell death in rat hippocampus. Progress in neuro-psychopharmacology & biological psychiatry, 2013, Aug-01, Volume: 45 Topics: Animals; Anticonvulsants; Bupropion; CA3 Region, Hippocampal; Cell Death; Dose-Response Relationship, Drug; Epilepsy, Temporal Lobe; Kainic Acid; Male; Microglia; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nerve Degeneration; Neurons; Phosphorylation; Proto-Oncogene Proteins c-fos; Rats; Seizures	2013
Lymphocyte-mediated neuroprotection in in vitro models of excitotoxicity involves astrocytic activation and the inhibition of MAP kinase signalling pathways. Neuropharmacology, 2014, Volume: 76 Pt A Topics: Animals; Astrocytes; Cell Death; Culture Media, Conditioned; Cytokines; Fluoroacetates; Hippocampus; Kainic Acid; Lymphocyte Activation; MAP Kinase Signaling System; Mice; Nerve Degeneration; Neuroprotective Agents; Signal Transduction; T-Lymphocytes	2014
Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration. The Journal of experimental medicine, 2013, Nov-18, Volume: 210, Issue:12 Topics: Animals; Brain; Disks Large Homolog 4 Protein; Glutamic Acid; Guanylate Kinases; Kainic Acid; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Membrane Proteins; Mice; Mice, Knockout; N-Methylaspartate; Nerve Degeneration; Nerve Tissue Proteins; Synapses	2013
Excitotoxin-induced caspase-3 activation and microtubule disintegration in axons is inhibited by taxol. Acta neuropathologica communications, 2013, Sep-09, Volume: 1 Topics: Animals; Axons; Caspase 3; Cells, Cultured; Cerebral Cortex; Cytoskeleton; Dendrites; Dose-Response Relationship, Drug; Kainic Acid; Mice; Microtubule-Associated Proteins; Microtubules; Nerve Degeneration; Neuroprotective Agents; Paclitaxel; Wallerian Degeneration	2013
Loss of hippocampal neurons after kainate treatment correlates with behavioral deficits. PloS one, 2014, Volume: 9, Issue:1 Topics: Animals; Avoidance Learning; Behavior, Animal; Hippocampus; Kainic Acid; Male; Maze Learning; Memory; Nerve Degeneration; Pyramidal Cells; Rats	2014
Post-seizure α-tocopherol treatment decreases neuroinflammation and neuronal degeneration induced by status epilepticus in rat hippocampus. Molecular neurobiology, 2014, Volume: 50, Issue:1 Topics: alpha-Tocopherol; Animals; Cell Death; Encephalitis; Hippocampus; Kainic Acid; Lipid Peroxidation; Male; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Status Epilepticus	2014
Delayed treatments with pharmacological modulators of pre- and postsynaptic mGlu receptors rescue the hippocampus from kainate-induced neurodegeneration. Neuroscience letters, 2014, Jun-06, Volume: 570 Topics: Animals; Bridged Bicyclo Compounds; Hippocampus; Kainic Acid; Microinjections; Nerve Degeneration; Pyridines; Rats, Wistar; Receptors, Metabotropic Glutamate; Time Factors	2014
Mice Lacking Functional Fas Death Receptors Are Protected from Kainic Acid-Induced Apoptosis in the Hippocampus. Molecular neurobiology, 2015, Volume: 52, Issue:1 Topics: Animals; Apoptosis; CA1 Region, Hippocampal; CA3 Region, Hippocampal; fas Receptor; Gene Expression Regulation; Hippocampus; In Situ Nick-End Labeling; Kainic Acid; Mice, Inbred C57BL; Mice, Inbred MRL lpr; Models, Biological; Nerve Degeneration; Neuroglia; Neuroprotection; Neurotoxins; Transcription, Genetic	2015
Prosaposin overexpression following kainic acid-induced neurotoxicity. PloS one, 2014, Volume: 9, Issue:12 Topics: Animals; Cerebral Cortex; Choroid Plexus; GABAergic Neurons; gamma-Aminobutyric Acid; Gene Expression Regulation; Hippocampus; In Situ Hybridization; Interneurons; Kainic Acid; Lysosomes; Male; Microscopy, Fluorescence; Nerve Degeneration; Neurons; Neurotoxicity Syndromes; Rats; Rats, Wistar; Saposins; Seizures; Up-Regulation	2014
Identifying the primary site of pathogenesis in amyotrophic lateral sclerosis - vulnerability of lower motor neurons to proximal excitotoxicity. Disease models & mechanisms, 2015, Volume: 8, Issue:3 Topics: Amyotrophic Lateral Sclerosis; Animals; Axons; Cell Line; Forelimb; Hindlimb; Kainic Acid; Mice, Inbred C57BL; Motor Activity; Motor Neurons; Nerve Degeneration; Neurotoxins; Spinal Cord	2015
Brain inflammation in a chronic epilepsy model: Evolving pattern of the translocator protein during epileptogenesis. Neurobiology of disease, 2015, Volume: 82 Topics: Animals; Autoradiography; Brain; Carrier Proteins; Chronic Disease; Disease Models, Animal; Disease Progression; Electrocorticography; Encephalitis; Epilepsy; Follow-Up Studies; Immunohistochemistry; Kainic Acid; Longitudinal Studies; Magnetic Resonance Imaging; Male; Nerve Degeneration; Neuroglia; Neurons; Positron-Emission Tomography; Rats, Wistar; Receptors, GABA-A	2015
A reduced susceptibility to chemoconvulsant stimulation in adenylyl cyclase 8 knockout mice. Epilepsy research, 2016, Volume: 119 Topics: Adenylyl Cyclases; Animals; Cell Death; Convulsants; Disease Models, Animal; Hippocampus; Kainic Acid; Male; MAP Kinase Signaling System; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Neurons; Pilocarpine; Seizures; Status Epilepticus	2016
Identification of Synaptotagmin 10 as Effector of NPAS4-Mediated Protection from Excitotoxic Neurodegeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, Mar-02, Volume: 36, Issue:9 Topics: Animals; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Cell Survival; Cells, Cultured; Female; Hippocampus; Humans; Kainic Acid; Male; Mice; Mice, Transgenic; Nerve Degeneration; Neurons; Neuroprotective Agents; Potassium Chloride; Pregnancy; Rats; Rats, Wistar; RNA, Small Interfering; Synapses; Synaptotagmins; Up-Regulation	2016
Pharmacologic suppression of oxidative damage and dendritic degeneration following kainic acid-induced excitotoxicity in mouse cerebrum. Neurotoxicology, 2008, Volume: 29, Issue:4 Topics: Animals; Cerebrum; Citrulline; Dendrites; Disease Models, Animal; Drug Interactions; Female; Functional Laterality; Isoprostanes; Kainic Acid; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neuroprotective Agents; Neurotoxicity Syndromes; Nitric Oxide Synthase; Oxidative Stress	2008
Behavioral alterations in a mouse model of temporal lobe epilepsy induced by intrahippocampal injection of kainate. Experimental neurology, 2008, Volume: 213, Issue:1 Topics: Animals; Convulsants; Dentate Gyrus; Depressive Disorder; Disease Models, Animal; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Female; Hippocampus; Kainic Acid; Learning Disabilities; Maze Learning; Memory Disorders; Mental Disorders; Mice; Mood Disorders; Nerve Degeneration; Neurocognitive Disorders; Neuropsychological Tests; Status Epilepticus	2008
Cyclin D1 in excitatory neurons of the adult brain enhances kainate-induced neurotoxicity. Neurobiology of disease, 2008, Volume: 31, Issue:2 Topics: Adult; Animals; Apoptosis; Convulsants; Cyclin D1; Disease Models, Animal; Epilepsy; Female; Hippocampus; Humans; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Neurotoxins; Pentylenetetrazole; Pyramidal Cells; Rats; Rats, Sprague-Dawley	2008
Identification and kainic acid-induced up-regulation of low-affinity p75 neurotrophin receptor (p75NTR) in the nigral dopamine neurons of adult rats. Neurochemistry international, 2008, Volume: 53, Issue:3-4 Topics: Acetylcholine; Animals; Apoptosis; Basal Nucleus of Meynert; Brain-Derived Neurotrophic Factor; Cell Count; Cell Survival; Choline O-Acetyltransferase; Dopamine; Excitatory Amino Acid Agonists; Kainic Acid; Male; Nerve Degeneration; Neurons; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Receptor, Nerve Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substantia Nigra; Tyrosine 3-Monooxygenase; Up-Regulation	2008
Introducing Black-Gold II, a highly soluble gold phosphate complex with several unique advantages for the histochemical localization of myelin. Brain research, 2008, Sep-10, Volume: 1229 Topics: Amphetamine; Animals; Fluoresceins; Kainic Acid; Myelin Sheath; Nerve Degeneration; Organic Chemicals; Peripheral Nervous System Diseases; Phosphates; Rats	2008
Transgenic overexpression of corticotropin releasing hormone provides partial protection against neurodegeneration in an in vivo model of acute excitotoxic stress. Neuroscience, 2008, Oct-15, Volume: 156, Issue:3 Topics: Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Cell Death; Corticotropin-Releasing Hormone; Disease Models, Animal; Excitatory Amino Acid Agonists; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hippocampus; Indoles; Intermediate Filament Proteins; Kainic Acid; Mice; Mice, Transgenic; Nerve Degeneration; Nerve Tissue Proteins; Nestin; Neurofilament Proteins; Neurotoxicity Syndromes; Plant Lectins; Proteins; Reaction Time; RNA, Untranslated; Seizures	2008
Does kainic acid induce partial brain lesion in an invertebrate model: sepia officinalis? Comparison with electrolytic lesion. Brain research, 2008, Oct-31, Volume: 1238 Topics: Animals; Brain; Decapodiformes; Electric Injuries; Excitatory Amino Acid Agonists; Kainic Acid; Microelectrodes; Microinjections; Nerve Degeneration	2008
Expression of L-serine biosynthetic enzyme 3-phosphoglycerate dehydrogenase (Phgdh) and neutral amino acid transporter ASCT1 following an excitotoxic lesion in the mouse hippocampus. Neurochemical research, 2009, Volume: 34, Issue:5 Topics: Amino Acid Transport System ASC; Animals; Hippocampus; Immunohistochemistry; Kainic Acid; Mice; Mice, Inbred ICR; Nerve Degeneration; Neuroglia; Neurons; Phosphoglycerate Dehydrogenase; Serine; Stereoisomerism; Up-Regulation	2009
Ginsenosides attenuate kainic acid-induced synaptosomal oxidative stress via stimulation of adenosine A(2A) receptors in rat hippocampus. Behavioural brain research, 2009, Jan-30, Volume: 197, Issue:1 Topics: Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Ginsenosides; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Seizures; Statistics, Nonparametric; Synaptosomes	2009
Protection against kainate neurotoxicity by ginsenosides: attenuation of convulsive behavior, mitochondrial dysfunction, and oxidative stress. Journal of neuroscience research, 2009, Feb-15, Volume: 87, Issue:3 Topics: Animals; Anticonvulsants; Antioxidants; Calcium; Ginsenosides; Glutathione; Hippocampus; Kainic Acid; Lipid Peroxidation; Male; Membrane Potential, Mitochondrial; Mitochondria; Motor Activity; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Seizures; Superoxide Dismutase	2009
Marked calpastatin (CAST) depletion in Alzheimer's disease accelerates cytoskeleton disruption and neurodegeneration: neuroprotection by CAST overexpression. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Nov-19, Volume: 28, Issue:47 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Animals; Brain; Calcium-Binding Proteins; Calpain; Case-Control Studies; Caspases; Cell Death; Cell Line, Transformed; Cytoskeleton; Excitatory Amino Acid Agonists; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation; Hippocampus; Humans; Kainic Acid; Male; Mice; Mice, Transgenic; Middle Aged; Nerve Degeneration; Postmortem Changes; RNA, Small Interfering; Transfection	2008
NMDA preconditioning and neuroprotection in vivo: delayed onset of kainic acid-induced neurodegeneration and c-Fos attenuation in CA3a neurons. Brain research, 2009, Feb-23, Volume: 1256 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cell Death; Dizocilpine Maleate; Female; Gene Expression; Genes, fos; Hippocampus; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate	2009
Localization of the transcription factor, sterol regulatory element binding protein-2 (SREBP-2) in the normal rat brain and changes after kainate-induced excitotoxic injury. Journal of chemical neuroanatomy, 2009, Volume: 37, Issue:2 Topics: Animals; Brain; Cerebral Cortex; Corpus Striatum; Down-Regulation; Encephalitis; Hippocampus; Immunohistochemistry; Injections, Intraventricular; Kainic Acid; Male; Nerve Degeneration; Neurons; Neurotoxins; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sterol Regulatory Element Binding Protein 2	2009
The levels of glutathione and nitrite-nitrate and the expression of Bcl-2 mRNA in ovariectomized rats treated by raloxifene against kainic acid. The International journal of neuroscience, 2009, Volume: 119, Issue:2 Topics: Animals; Apoptosis; Disease Models, Animal; Female; Glutathione; Kainic Acid; Nerve Degeneration; Neuroprotective Agents; Nitrates; Nitric Oxide; Nitrites; Ovariectomy; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; RNA, Messenger; Selective Estrogen Receptor Modulators; Treatment Outcome; Up-Regulation	2009
Temporal profile of clinical signs and histopathologic changes in an F-344 rat model of kainic acid-induced mesial temporal lobe epilepsy. Toxicologic pathology, 2008, Volume: 36, Issue:7 Topics: Animals; Astrocytes; Behavior, Animal; Dentate Gyrus; Disease Models, Animal; Doublecortin Protein; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Gliosis; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Microglia; Mossy Fibers, Hippocampal; Nerve Degeneration; Rats; Rats, Inbred F344; Seizures; Status Epilepticus; Thalamus	2008
Kainic acid intraocular injections during the postnatal critical period induce plastic changes in the visual system. Neuroscience research, 2009, Volume: 63, Issue:4 Topics: Age Factors; Animals; Animals, Newborn; Excitatory Amino Acid Agonists; Functional Laterality; Kainic Acid; Nerve Degeneration; Neuronal Plasticity; Optic Nerve; Rats; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells; Superior Colliculi; Visual Pathways	2009
Postconditioning and anticonditioning: possibilities to interfere to evoked apoptosis. Cellular and molecular neurobiology, 2009, Volume: 29, Issue:6-7 Topics: Animals; Apoptosis; Cell Count; Cell Survival; Fluoresceins; Ginkgo biloba; Hippocampus; Immunohistochemistry; Kainic Acid; Maze Learning; Nerve Degeneration; Neurons; Norepinephrine; Organic Chemicals; Plant Extracts; Rats	2009
The complement factor C5a receptor is upregulated in NFL-/- mouse motor neurons. Journal of neuroimmunology, 2009, May-29, Volume: 210, Issue:1-2 Topics: Amyotrophic Lateral Sclerosis; Animals; Complement C5a; Disease Models, Animal; Excitatory Amino Acid Agonists; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Neuron Disease; Motor Neurons; Nerve Degeneration; Neurofilament Proteins; Neurotoxins; Receptor, Anaphylatoxin C5a; Up-Regulation	2009
Presynaptic regulation of astroglial excitatory neurotransmitter transporter GLT1. Neuron, 2009, Mar-26, Volume: 61, Issue:6 Topics: Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Cerebral Cortex; Coculture Techniques; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Embryo, Mammalian; Excitatory Amino Acid Agents; Excitatory Amino Acid Transporter 2; Green Fluorescent Proteins; Humans; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microfluidic Analytical Techniques; Mutagenesis; Nerve Degeneration; Neurons; NF-kappa B; Presynaptic Terminals; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Spinal Cord Injuries; Superoxide Dismutase; Synapses; Tetrodotoxin; Transfection; Up-Regulation	2009
A role for the parafascicular thalamic nucleus in the development of morphine dependence and withdrawal. Brain research, 2009, May-19, Volume: 1271 Topics: Animals; Cell Nucleus; Denervation; Disease Models, Animal; Electrophysiology; Intralaminar Thalamic Nuclei; Kainic Acid; Male; Microscopy, Electron, Transmission; Morphine; Morphine Dependence; Narcotics; Nerve Degeneration; Neurons; Neurotoxins; Organelles; Rats; Rats, Wistar; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance Withdrawal Syndrome	2009
Apolipoprotein D modulates F2-isoprostane and 7-ketocholesterol formation and has a neuroprotective effect on organotypic hippocampal cultures after kainate-induced excitotoxic injury. Neuroscience letters, 2009, May-22, Volume: 455, Issue:3 Topics: Aldehydes; Animals; Apolipoproteins D; Arachidonic Acid; Binding Sites; Cholesterol; F2-Isoprostanes; Hippocampus; Kainic Acid; Ketocholesterols; L-Lactate Dehydrogenase; Microtubule-Associated Proteins; Nerve Degeneration; Neurons; Neurotoxins; Organ Culture Techniques; Oxidative Stress; Rats; Rats, Wistar	2009
Activin A is essential for neurogenesis following neurodegeneration. Stem cells (Dayton, Ohio), 2009, Volume: 27, Issue:6 Topics: Activins; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Excitatory Amino Acid Agonists; Fluorescent Antibody Technique; Gliosis; Hippocampus; Inflammation; Kainic Acid; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Nerve Degeneration; Neurogenesis	2009
Early-life experience alters response of developing brain to seizures. Brain research, 2009, Aug-18, Volume: 1285 Topics: Aging; Animals; Animals, Newborn; Apoptosis; Brain; Convulsants; Disease Models, Animal; Encephalitis; Environmental Exposure; Epilepsy; Exploratory Behavior; Female; Gliosis; Hippocampus; Kainic Acid; Male; Maternal Deprivation; Microglia; Nerve Degeneration; Physical Stimulation; Rats; Time	2009
Pathological alterations in GABAergic interneurons and reduced tonic inhibition in the basolateral amygdala during epileptogenesis. Neuroscience, 2009, Sep-29, Volume: 163, Issue:1 Topics: Amygdala; Animals; Convulsants; Down-Regulation; Epilepsy; Fluoresceins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Immunohistochemistry; Inhibitory Postsynaptic Potentials; Interneurons; Kainic Acid; Male; Nerve Degeneration; Neural Inhibition; Organic Chemicals; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Kainic Acid; Staining and Labeling; Status Epilepticus; Synaptic Transmission	2009
Differential role of gonadal hormones on kainic acid-induced neurodegeneration in medial amygdaloid nucleus of female and male rats. Neuroscience, 2009, Oct-20, Volume: 163, Issue:3 Topics: Amygdala; Androgens; Animals; Cell Survival; Estrogens; Female; Gonadal Hormones; Kainic Acid; Male; Nerve Degeneration; Neurons; Orchiectomy; Ovariectomy; Rats; Rats, Wistar; Seizures; Sex Factors; Testosterone	2009
Excitotoxic motoneuron degeneration induced by glutamate receptor agonists and mitochondrial toxins in organotypic cultures of chick embryo spinal cord. The Journal of comparative neurology, 2009, Oct-01, Volume: 516, Issue:4 Topics: Animals; Calcium Signaling; Chick Embryo; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Malonates; Mitochondria; Motor Neuron Disease; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Organ Culture Techniques; Propionates; Riluzole; Spinal Cord	2009
Kainic acid-induced F-344 rat model of mesial temporal lobe epilepsy: gene expression and canonical pathways. Toxicologic pathology, 2009, Volume: 37, Issue:6 Topics: Animals; Behavior, Animal; Cluster Analysis; Disease Models, Animal; Epilepsy, Temporal Lobe; Gene Expression Regulation; Hippocampus; Histocytochemistry; Inflammation; Kainic Acid; Male; Nerve Degeneration; Neuronal Plasticity; Rats; Rats, Inbred F344; Reproducibility of Results; Signal Transduction; Toxicogenetics	2009
Neuroprotective effects of IGF-I following kainic acid-induced hippocampal degeneration in the rat. Cellular and molecular neurobiology, 2010, Volume: 30, Issue:3 Topics: Animals; Biomarkers; Cell Death; Cytoprotection; Dentate Gyrus; Disease Models, Animal; Epilepsy, Temporal Lobe; Fluoresceins; Glial Fibrillary Acidic Protein; Gliosis; Hippocampus; HSP72 Heat-Shock Proteins; Insulin-Like Growth Factor I; Kainic Acid; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Organic Chemicals; Rats; Rats, Wistar; Staining and Labeling; Stress, Physiological	2010
Kainic acid-activated microglia mediate increased excitability of rat hippocampal neurons in vitro and in vivo: crucial role of interleukin-1beta. Neuroimmunomodulation, 2010, Volume: 17, Issue:1 Topics: Action Potentials; Animals; Animals, Newborn; Antibodies, Neutralizing; Cells, Cultured; Culture Media, Conditioned; Encephalitis; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; Interleukin-1beta; Kainic Acid; Male; Microglia; Nerve Degeneration; Neurons; Neurotoxins; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Up-Regulation	2010
A metallothionein mimetic peptide protects neurons against kainic acid-induced excitotoxicity. Journal of neuroscience research, 2010, Volume: 88, Issue:5 Topics: Animals; Blood-Brain Barrier; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Temporal Lobe; Hippocampus; Intercellular Signaling Peptides and Proteins; Kainic Acid; Male; Metallothionein; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Peptides; Rats; Rats, Wistar; Seizures	2010
Urokinase-type plasminogen activator regulates neurodegeneration and neurogenesis but not vascular changes in the mouse hippocampus after status epilepticus. Neurobiology of disease, 2010, Volume: 37, Issue:3 Topics: Animals; Cell Movement; Cerebral Arteries; Cytoprotection; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Epilepsy; Hippocampus; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microtubule-Associated Proteins; Neovascularization, Pathologic; Nerve Degeneration; Neurogenesis; Neuropeptides; Neurotoxins; Pyramidal Cells; Status Epilepticus; Stem Cells; Urokinase-Type Plasminogen Activator	2010
Tumour necrosis factor alpha induces rapid reduction in AMPA receptor-mediated calcium entry in motor neurones by increasing cell surface expression of the GluR2 subunit: relevance to neurodegeneration. Journal of neurochemistry, 2010, Volume: 113, Issue:3 Topics: Animals; Biotinylation; Blotting, Western; Calcium; Calcium Signaling; Cell Survival; Cells, Cultured; Excitatory Amino Acid Agonists; Female; Fluorescent Antibody Technique; Kainic Acid; Mice; Motor Neurons; Nerve Degeneration; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Pregnancy; Receptors, AMPA; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; Spectrometry, Fluorescence; Tumor Necrosis Factor-alpha	2010
Kainic acid-induced early genes activation and neuronal death in the medial extended amygdala of rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2011, Volume: 63, Issue:3 Topics: Amygdala; Animals; Cell Death; Gene Expression; Genes, Immediate-Early; Kainic Acid; Male; Nerve Degeneration; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Status Epilepticus	2011
Midkine, heparin-binding growth factor, blocks kainic acid-induced seizure and neuronal cell death in mouse hippocampus. BMC neuroscience, 2010, Mar-26, Volume: 11 Topics: Animals; Anticonvulsants; Astrocytes; Biomarkers; Cell Death; Cytokines; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Hippocampus; Injections, Intraventricular; Interneurons; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Midkine; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Pyramidal Cells	2010
BACE1 deficiency causes altered neuronal activity and neurodegeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Jun-30, Volume: 30, Issue:26 Topics: Action Potentials; Aging; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Axons; Brain; Cell Membrane; Hippocampus; In Vitro Techniques; Kainic Acid; Membrane Potentials; Mice; Mice, Knockout; Nerve Degeneration; Neurons; Phenotype; Seizures; Sodium Channels	2010
PSA-NCAM-dependent GDNF signaling limits neurodegeneration and epileptogenesis in temporal lobe epilepsy. The European journal of neuroscience, 2010, Volume: 32, Issue:1 Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Focal Adhesion Protein-Tyrosine Kinases; Glial Cell Line-Derived Neurotrophic Factor; Glycoside Hydrolases; Hippocampus; Kainic Acid; Male; Mice; Nerve Degeneration; Neural Cell Adhesion Molecule L1; Neuroprotective Agents; Sialic Acids; Signal Transduction	2010
Kainic acid-induced seizures activate GSK-3β in the hippocampus of D2R-/- mice. Neuroreport, 2010, Aug-23, Volume: 21, Issue:12 Topics: Animals; Apoptosis; Disease Models, Animal; Enzyme Activation; Excitatory Amino Acid Agonists; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Kainic Acid; Mice; Mice, Knockout; Nerve Degeneration; Proto-Oncogene Proteins c-akt; Receptors, Dopamine D2; Seizures; Signal Transduction	2010
Changes in hippocampal GABAA/cBZR density during limbic epileptogenesis: relationship to cell loss and mossy fibre sprouting. Neurobiology of disease, 2011, Volume: 41, Issue:2 Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Kainic Acid; Male; Mossy Fibers, Hippocampal; Nerve Degeneration; Neuronal Plasticity; Random Allocation; Rats; Rats, Wistar; Receptors, GABA-A; Recovery of Function; Status Epilepticus	2011
Kainic acid-induced neurodegeneration and activation of inflammatory processes in organotypic hippocampal slice cultures: treatment with cyclooxygenase-2 inhibitor does not prevent neuronal death. Neuropharmacology, 2011, Volume: 60, Issue:7-8 Topics: Animals; Cell Culture Techniques; Cell Death; Cyclooxygenase 2 Inhibitors; Dinoprostone; Excitatory Amino Acid Agonists; Hippocampus; Inflammation; Kainic Acid; Male; Nerve Degeneration; Neurons; Nitrobenzenes; Rats; Rats, Sprague-Dawley; Sulfonamides	2011
Knockout of Zn transporters Zip-1 and Zip-3 attenuates seizure-induced CA1 neurodegeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Jan-05, Volume: 31, Issue:1 Topics: Animals; CA1 Region, Hippocampal; Cation Transport Proteins; Cell Death; Disease Models, Animal; Electroencephalography; Excitatory Amino Acid Agonists; Fluoresceins; Gene Expression Regulation, Viral; Green Fluorescent Proteins; Kainic Acid; Mice; Mice, Transgenic; Nerve Degeneration; Neurons; Organic Chemicals; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Seizures; Video Recording; Zinc	2011
An approach to experimental synaptic pathology using green fluorescent protein-transgenic mice and gene knockout mice to show mitochondrial permeability transition pore-driven excitotoxicity in interneurons and motoneurons. Toxicologic pathology, 2011, Volume: 39, Issue:1 Topics: Animals; Apoptosis; Cyclophilins; Female; Green Fluorescent Proteins; Interneurons; Kainic Acid; Male; Mice; Mice, Knockout; Mice, Transgenic; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Models, Animal; Motor Neurons; Nerve Degeneration; Neurotoxins; Peptidyl-Prolyl Isomerase F; Quinolinic Acid; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sex Factors; Spinal Cord	2011
Decrease of calbindin-d28k, calretinin, and parvalbumin by taurine treatment does not induce a major susceptibility to kainic acid. Journal of neuroscience research, 2011, Volume: 89, Issue:7 Topics: Animals; Calbindin 1; Calbindin 2; Calbindins; Calcium-Binding Proteins; Disease Models, Animal; Disease Susceptibility; Down-Regulation; Drug Resistance; Epilepsy; Kainic Acid; Male; Mice; Mice, Inbred Strains; Nerve Degeneration; Neurotoxins; Parvalbumins; S100 Calcium Binding Protein G; Taurine	2011
Dietary supplementation with α-tocopherol reduces neuroinflammation and neuronal degeneration in the rat brain after kainic acid-induced status epilepticus. Free radical research, 2011, Volume: 45, Issue:10 Topics: alpha-Tocopherol; Animals; Antioxidants; Biological Availability; Brain; Dietary Supplements; Humans; Inflammation; Kainic Acid; Lipid Peroxidation; Male; Nerve Degeneration; Neurons; Oxidative Stress; Rats; Rats, Sprague-Dawley; Status Epilepticus	2011
IGF-I ameliorates hippocampal neurodegeneration and protects against cognitive deficits in an animal model of temporal lobe epilepsy. Experimental neurology, 2011, Volume: 231, Issue:2 Topics: Animals; Cell Count; Cell Death; Disease Models, Animal; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Hippocampus; Insulin-Like Growth Factor I; Kainic Acid; Male; Maze Learning; Memory; Mice; Nerve Degeneration; Neurogenesis; Neurons	2011
Involvement of cyclin-dependent kinase-5 in the kainic acid-mediated degeneration of glutamatergic synapses in the rat hippocampus. The European journal of neuroscience, 2011, Volume: 34, Issue:8 Topics: Animals; Calcium; Calpain; Cells, Cultured; Cyclin-Dependent Kinase 5; Disks Large Homolog 4 Protein; Excitatory Amino Acid Agonists; GluK2 Kainate Receptor; GluK3 Kainate Receptor; Hippocampus; Humans; Intracellular Signaling Peptides and Proteins; Kainic Acid; Male; Membrane Proteins; Nerve Degeneration; Neurons; Rats; Rats, Wistar; Receptors, Kainic Acid; Synapses	2011
Selective mGluR1 antagonist EMQMCM inhibits the kainate-induced excitotoxicity in primary neuronal cultures and in the rat hippocampus. Neurotoxicity research, 2012, Volume: 21, Issue:4 Topics: Animals; Apoptosis; Caspase 3; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Kainic Acid; L-Lactate Dehydrogenase; Male; Mice; Microinjections; Nerve Degeneration; Neuroprotective Agents; Primary Cell Culture; Quinolines; Rats; Rats, Wistar	2012
Intracranial V. cholerae sialidase protects against excitotoxic neurodegeneration. PloS one, 2011, Volume: 6, Issue:12 Topics: Animals; Anxiety; G(M1) Ganglioside; Gene Deletion; Inflammation; Kainic Acid; Memory; Mice; Motor Activity; Nerve Degeneration; Neuraminidase; Neuroprotective Agents; Neurotoxins; Sialyltransferases; Skull; Vibrio cholerae	2011
Matrix metalloproteinase-7 regulates cleavage of pro-nerve growth factor and is neuroprotective following kainic acid-induced seizures. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Jan-11, Volume: 32, Issue:2 Topics: Animals; Animals, Newborn; Disease Models, Animal; Epilepsy; Kainic Acid; Male; Matrix Metalloproteinase 7; Nerve Degeneration; Nerve Growth Factors; Neuroprotective Agents; Organ Culture Techniques; Protein Precursors; Rats; Rats, Sprague-Dawley	2012
Temporal progression of kainic acid induced changes in vascular laminin expression in rat brain with neuronal and glial correlates. Current neurovascular research, 2012, Volume: 9, Issue:2 Topics: Animals; Astrocytes; Blood-Brain Barrier; Cerebral Arteries; Disease Models, Animal; Disease Progression; Glial Fibrillary Acidic Protein; Gliosis; Kainic Acid; Laminin; Male; Nerve Degeneration; Neurotoxins; Rats; Rats, Sprague-Dawley; Time Factors; Up-Regulation	2012
Sequel of spontaneous seizures after kainic acid-induced status epilepticus and associated neuropathological changes in the subiculum and entorhinal cortex. Neuropharmacology, 2012, Volume: 63, Issue:5 Topics: Animals; Anticonvulsants; Astrocytes; Diazepam; Disease Models, Animal; Drug Resistance; Entorhinal Cortex; Epilepsy, Temporal Lobe; Hippocampus; Kainic Acid; Male; Marine Toxins; Microglia; Nerve Degeneration; Neurogenesis; Neurons; Organ Specificity; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Status Epilepticus; Time Factors	2012
Kainic acid-induced neuronal degeneration in hippocampal pyramidal neurons is driven by both intrinsic and extrinsic factors: analysis of FVB/N↔C57BL/6 chimeras. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Aug-29, Volume: 32, Issue:35 Topics: Animals; Apoptosis; Female; Hippocampus; Humans; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Degeneration; Pregnancy; Pyramidal Cells; Radiation Chimera	2012
Expression of CD200 in alternative activation of microglia following an excitotoxic lesion in the mouse hippocampus. Brain research, 2012, Oct-24, Volume: 1481 Topics: Animals; Antigens, CD; Disease Models, Animal; Encephalitis; Excitatory Amino Acid Agonists; Hippocampus; Interleukin-4; Kainic Acid; Lipopolysaccharides; Male; Mice; Mice, Inbred Strains; Microglia; Nerve Degeneration; Primary Cell Culture; Rats; Rats, Sprague-Dawley	2012
Beneficial effects of natural phenolics on levodopa methylation and oxidative neurodegeneration. Brain research, 2013, Feb-25, Volume: 1497 Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Antiparkinson Agents; Carbidopa; Catechin; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Disease Models, Animal; Excitatory Amino Acid Agonists; Fluoresceins; Glial Fibrillary Acidic Protein; Hippocampus; Hydroxybenzoates; In Vitro Techniques; Kainic Acid; Levodopa; Male; Methylation; Mice; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Reserpine; Time Factors; Tyrosine	2013
Depletion of polysialic acid from neural cell adhesion molecule (PSA-NCAM) increases CA3 dendritic arborization and increases vulnerability to excitotoxicity. Experimental neurology, 2013, Volume: 241 Topics: Analysis of Variance; Animals; Body Mass Index; CA3 Region, Hippocampal; Dendrites; Disease Models, Animal; Excitatory Amino Acid Agonists; Fluoresceins; Gene Expression Regulation; Kainic Acid; Male; Metalloendopeptidases; Nerve Degeneration; Neural Cell Adhesion Molecules; Organic Chemicals; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sialic Acids; Silver Staining; Stress, Psychological	2013
Urokinase-type plasminogen activator receptor modulates epileptogenesis in mouse model of temporal lobe epilepsy. Molecular neurobiology, 2013, Volume: 47, Issue:3 Topics: Animals; Apoptosis; Blood-Brain Barrier; Body Temperature; Cell Movement; Dentate Gyrus; Disease Models, Animal; Doublecortin Domain Proteins; Epilepsy, Temporal Lobe; Genotype; Inflammation; Kainic Acid; Macrophages; Male; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Mossy Fibers, Hippocampal; Nerve Degeneration; Neurogenesis; Neuropeptides; Receptors, Urokinase Plasminogen Activator; Status Epilepticus; Survival Analysis; T-Lymphocytes	2013
Spinal cord mGlu1a receptors: possible target for amyotrophic lateral sclerosis therapy. Pharmacology, biochemistry, and behavior, 2002, Volume: 73, Issue:2 Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Survival; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Ganglia, Spinal; Glycine; Humans; Immunohistochemistry; Kainic Acid; Motor Neurons; Nerve Degeneration; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord	2002
Glial expression of estrogen and androgen receptors after rat brain injury. The Journal of comparative neurology, 2002, Aug-26, Volume: 450, Issue:3 Topics: Animals; Astrocytes; Brain; Brain Injuries; Disease Models, Animal; Estrogen Receptor alpha; Estrogen Receptor beta; Glial Fibrillary Acidic Protein; Gliosis; Immunohistochemistry; Kainic Acid; Lectins; Male; Microglia; Nerve Degeneration; Nerve Regeneration; Neuroglia; Plant Lectins; Rats; Rats, Wistar; Receptors, Androgen; Receptors, Estrogen; Vimentin	2002
Genetic influences on secondary degeneration and wound healing following spinal cord injury in various strains of mice. The Journal of comparative neurology, 2002, Sep-23, Volume: 451, Issue:3 Topics: Animals; Drug Resistance; Excitatory Amino Acid Agonists; Female; Kainic Acid; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nerve Degeneration; Nerve Regeneration; Neurons; Neurotoxins; Spinal Cord; Spinal Cord Injuries; Wound Healing	2002
Nitric oxide synthase inhibition and glutamate binding in quinolinate-lesioned rat hippocampus. Physiological research, 2002, Volume: 51, Issue:3 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cell Membrane; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Kainic Acid; Male; Molsidomine; N-Methylaspartate; Nerve Degeneration; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Quinolinic Acid; Quisqualic Acid; Rats; Rats, Wistar; Tritium	2002
Caspase inhibitors reduce the apoptotic but not necrotic component of kainate injury in primary murine cortical neuronal cultures. Neurological research, 2002, Volume: 24, Issue:8 Topics: Animals; Apoptosis; Brain Ischemia; Caspase Inhibitors; Caspases; Cell Nucleus; Cells, Cultured; Cerebral Cortex; Down-Regulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Fetus; Kainic Acid; Mice; Necrosis; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins	2002
Ability of NMDA and non-NMDA receptor antagonists to inhibit cerebral ischemic damage in aged rats. Brain research, 2003, Feb-21, Volume: 964, Issue:1 Topics: Aging; Animals; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Infarction, Middle Cerebral Artery; Kainic Acid; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Telencephalon	2003
Treatment with 7-nitroindazole enhances kainic acid induced cholinergic neurotoxicity in the rat striatum: a neuroprotective role for neuronal nitric oxide. Cellular and molecular neurobiology, 2002, Volume: 22, Issue:5-6 Topics: Animals; Cell Death; Choline O-Acetyltransferase; Cholinergic Fibers; Drug Synergism; Enzyme Inhibitors; Indazoles; Kainic Acid; Neostriatum; Nerve Degeneration; Neurons; Neurotoxins; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Up-Regulation	2002
Lesion of caudate-putamen interneurons with kainic acid alters dopamine and serotonin metabolism in the olfactory tubercle of the rat. Cellular and molecular neurobiology, 2002, Volume: 22, Issue:5-6 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Cell Death; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Interneurons; Kainic Acid; Neostriatum; Nerve Degeneration; Neural Inhibition; Neural Pathways; Neurotoxins; Olfactory Pathways; Rats; Rats, Sprague-Dawley; Serotonin	2002
Heat shock protein 27 delivered via a herpes simplex virus vector can protect neurons of the hippocampus against kainic-acid-induced cell loss. Brain research. Molecular brain research, 2003, Mar-17, Volume: 111, Issue:1-2 Topics: Animals; Cell Count; Cell Death; Disease Models, Animal; Epilepsy; Genetic Vectors; Heat-Shock Proteins; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley; Simplexvirus; Stress, Physiological; Treatment Outcome	2003
Differences in ionotropic glutamate receptor subunit expression are not responsible for strain-dependent susceptibility to excitotoxin-induced injury. Brain research. Molecular brain research, 2003, Apr-10, Volume: 112, Issue:1-2 Topics: Animals; Cell Death; Disease Models, Animal; Drug Resistance; Epilepsy; Genetic Predisposition to Disease; Glutamic Acid; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurotoxins; Protein Subunits; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Species Specificity; Synaptic Transmission	2003
Kainate exacerbates beta-amyloid toxicity in rat hippocampus. Neuroscience letters, 2003, Apr-17, Volume: 340, Issue:3 Topics: Amyloid beta-Peptides; Animals; Drug Synergism; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Peptide Fragments; Rats; Rats, Sprague-Dawley	2003
Activation of neuropeptide Y receptors is neuroprotective against excitotoxicity in organotypic hippocampal slice cultures. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:9 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dentate Gyrus; Hippocampus; Kainic Acid; Nerve Degeneration; Neuroprotective Agents; Organ Culture Techniques; Pyramidal Cells; Rats; Receptors, Neuropeptide; Receptors, Neuropeptide Y	2003
N-methyl-D-aspartate receptor blockade after status epilepticus protects against limbic brain damage but not against epilepsy in the kainate model of temporal lobe epilepsy. Neuroscience, 2003, Volume: 118, Issue:3 Topics: Animals; Cell Death; Dentate Gyrus; Disease Models, Animal; Dizocilpine Maleate; DNA Fragmentation; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Female; Hippocampus; Kainic Acid; Limbic System; Mediodorsal Thalamic Nucleus; Nerve Degeneration; Neurons; Neuroprotective Agents; Olfactory Pathways; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Status Epilepticus; Treatment Outcome	2003
Topiramate protects against glutamate- and kainate-induced neurotoxicity in primary neuronal-astroglial cultures. Epilepsy research, 2003, Volume: 54, Issue:1 Topics: Animals; Animals, Newborn; Anticonvulsants; Astrocytes; Calcium; Calcium Signaling; Cell Membrane; Cell Survival; Cells, Cultured; Fructose; Glutamic Acid; Immunohistochemistry; Kainic Acid; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Phenytoin; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Topiramate; Valproic Acid	2003
Altered expression of GABAB receptors in the hippocampus after kainic-acid-induced seizures in rats. Brain research. Molecular brain research, 2003, May-12, Volume: 113, Issue:1-2 Topics: Animals; Dentate Gyrus; Down-Regulation; Epilepsy; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Neural Inhibition; Neural Pathways; Neurons; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; RNA, Messenger; Synaptic Transmission; Up-Regulation	2003
The hippocampal laminin matrix is dynamic and critical for neuronal survival. Molecular biology of the cell, 2003, Volume: 14, Issue:7 Topics: Animals; Binding, Competitive; Cell Adhesion; Cell Survival; Extracellular Matrix; Fibrinolysin; Hippocampus; Kainic Acid; Laminin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Neurons; Plasminogen; Protein Binding	2003
GluR2(B) knockdown accelerates CA3 injury after kainate seizures. Journal of neuropathology and experimental neurology, 2003, Volume: 62, Issue:7 Topics: Animals; Calcium Signaling; Cell Death; Epilepsy; Glutamic Acid; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Nerve Degeneration; Neurons; Neurotoxins; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Status Epilepticus	2003
Effect of gamma-hydroxybutyrate in two rat models of focal cerebral damage. Brain research, 2003, Oct-03, Volume: 986, Issue:1-2 Topics: Animals; Apomorphine; Brain; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Kainic Acid; Learning; Male; Memory Disorders; Motor Activity; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Rats; Rats, Wistar; Sodium Oxybate	2003
Genetic basis of kainate-induced excitotoxicity in mice: phenotypic modulation of seizure-induced cell death. Epilepsy research, 2003, Volume: 55, Issue:3 Topics: Animals; Cell Count; Cell Death; Chimera; Excitatory Amino Acid Agonists; Female; Fluoresceins; Fluorescent Dyes; Hippocampus; Kainic Acid; Male; Mice; Mice, Inbred Strains; Nerve Degeneration; Neurons; Organic Chemicals; Phenotype; Seizures; Species Specificity; Staining and Labeling; Time Factors	2003
Group IIA secretory phospholipase A2 stimulates exocytosis and neurotransmitter release in pheochromocytoma-12 cells and cultured rat hippocampal neurons. Neuroscience, 2003, Volume: 121, Issue:4 Topics: Animals; Animals, Newborn; Calcium Signaling; Cell Membrane; Cells, Cultured; Chelating Agents; Enzyme Inhibitors; Exocytosis; Group II Phospholipases A2; Hippocampus; Kainic Acid; Membrane Fusion; Membrane Potentials; Nerve Degeneration; Neurons; Neurotransmitter Agents; Patch-Clamp Techniques; PC12 Cells; Phospholipases A; Phospholipases A2; Presynaptic Terminals; Rats; Rats, Wistar; Synaptic Vesicles	2003
Critical role of calpain-mediated cleavage of calcineurin in excitotoxic neurodegeneration. The Journal of biological chemistry, 2004, Feb-06, Volume: 279, Issue:6 Topics: Amino Acid Sequence; Animals; Binding Sites; Calcineurin; Calpain; Cells, Cultured; Glutamic Acid; Hippocampus; Kainic Acid; Male; Mice; Models, Neurological; Molecular Sequence Data; Nerve Degeneration; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2004
Kainic acid-induced convulsions cause prolonged changes in the chondroitin sulfate proteoglycans neurocan and phosphacan in the limbic structures. Experimental neurology, 2003, Volume: 184, Issue:1 Topics: Animals; Antibodies, Monoclonal; Astrocytes; Behavior, Animal; Chondroitin Sulfate Proteoglycans; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Immunoblotting; Immunoglobulin G; Kainic Acid; Lectins, C-Type; Limbic System; Male; Microscopy, Confocal; Microscopy, Fluorescence; Nerve Degeneration; Nerve Net; Nerve Tissue Proteins; Neurocan; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor-Like Protein Tyrosine Phosphatases, Class 5; Seizures	2003
PARP cleavage, DNA fragmentation, and pyknosis during excitotoxin-induced neuronal death. Experimental neurology, 2003, Volume: 184, Issue:1 Topics: Animals; Blotting, Western; Caspase 3; Caspases; Cell Death; Cell Survival; Cerebral Cortex; DNA Fragmentation; Excitatory Amino Acid Agonists; Fluorescent Dyes; In Situ Nick-End Labeling; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Phenotype; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; Rats; Rats, Long-Evans; Spectrin	2003
Glia activation and cytokine increase in rat hippocampus by kainic acid-induced status epilepticus during postnatal development. Neurobiology of disease, 2003, Volume: 14, Issue:3 Topics: Aging; Animals; Animals, Newborn; Cytokines; Disease Models, Animal; Disease Susceptibility; Epilepsy; Female; Gliosis; Hippocampus; Inflammation Mediators; Interleukin 1 Receptor Antagonist Protein; Kainic Acid; Male; Nerve Degeneration; Neuroglia; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sialoglycoproteins; Status Epilepticus; Up-Regulation	2003
Interactive effects of excitotoxic injury and dietary restriction on microgliosis and neurogenesis in the hippocampus of adult mice. Neuromolecular medicine, 2003, Volume: 4, Issue:3 Topics: Animals; Bromodeoxyuridine; Cell Division; Down-Regulation; Epilepsy; Food Deprivation; Gliosis; Hippocampus; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Microglia; Nerve Degeneration; Nerve Regeneration; Neurons; Neurotoxins; Stem Cells	2003
Translamellar disinhibition in the rat hippocampal dentate gyrus after seizure-induced degeneration of vulnerable hilar neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Jan-28, Volume: 24, Issue:4 Topics: Animals; Axonal Transport; Cell Survival; Dentate Gyrus; Diffusion; Electric Stimulation; Fluorescent Dyes; GABA Antagonists; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Neural Inhibition; Neurons; Perforant Pathway; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Seizures; Stilbamidines	2004
Early increase of apoptosis-linked gene-2 interacting protein X in areas of kainate-induced neurodegeneration. Neuroscience, 2004, Volume: 123, Issue:4 Topics: Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; Calcium-Binding Proteins; Carrier Proteins; Cell Cycle Proteins; Cell Death; Cerebral Cortex; Endosomal Sorting Complexes Required for Transport; Excitatory Amino Acid Agonists; Hippocampus; Humans; Immunohistochemistry; Kainic Acid; Male; Nerve Degeneration; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Staining and Labeling; Synaptophysin; Time Factors	2004
A role of glial fibrillary acidic protein in hippocampal degeneration after cerebral trauma or kainate-induced seizure. Acta neurochirurgica. Supplement, 2003, Volume: 86 Topics: Animals; Brain Injuries; Cell Survival; Glial Fibrillary Acidic Protein; Hippocampus; Kainic Acid; Mice; Mice, Knockout; Nerve Degeneration; Neurons; Seizures; Wounds, Nonpenetrating	2003
Latency to onset of status epilepticus determines molecular mechanisms of seizure-induced cell death. Brain research. Molecular brain research, 2004, Feb-05, Volume: 121, Issue:1-2 Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Boron Compounds; Calpain; Caspase 3; Caspases; Deoxyribonucleases; Disease Models, Animal; DNA Fragmentation; Kainic Acid; Male; Necrosis; Nerve Degeneration; Proteins; Rats; Rats, Sprague-Dawley; Seizures; Spectrin; Status Epilepticus; Time	2004
Lipoprotein lipase and endothelial lipase expression in mouse brain: regional distribution and selective induction following kainic acid-induced lesion and focal cerebral ischemia. Neurobiology of disease, 2004, Volume: 15, Issue:2 Topics: Animals; Brain; Brain Ischemia; Cerebral Cortex; Cerebral Infarction; Corpus Striatum; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hippocampus; Infarction, Middle Cerebral Artery; Kainic Acid; Lipase; Lipoprotein Lipase; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurotoxins; Pyramidal Cells; Reaction Time; RNA, Messenger; Up-Regulation	2004
Kainic acid-induced naip expression in the hippocampus is blocked in mice lacking TNF receptors. Brain research. Molecular brain research, 2004, Apr-07, Volume: 123, Issue:1-2 Topics: Animals; Apoptosis; Brain Ischemia; Disease Models, Animal; Genetic Predisposition to Disease; Hippocampus; Kainic Acid; Mice; Mice, Knockout; Nerve Degeneration; Nerve Tissue Proteins; Neuronal Apoptosis-Inhibitory Protein; Neuroprotective Agents; Receptors, Tumor Necrosis Factor; RNA, Messenger; Tumor Necrosis Factor-alpha	2004
Response to kainic acid injections: changes in staining for zinc, FOS, cell death and glial response in the rat forebrain. Neuroscience, 2004, Volume: 125, Issue:3 Topics: Animals; Cell Compartmentation; Cell Death; Cytoplasm; Fluoresceins; Fluorescent Dyes; Gliosis; Glutamic Acid; Kainic Acid; Male; Nerve Degeneration; Neurotoxins; Organic Chemicals; Presynaptic Terminals; Prosencephalon; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Reaction Time; Seizures; Synaptic Transmission; Synaptic Vesicles; Zinc	2004
Nutritional iron deprivation attenuates kainate-induced neurotoxicity in rats: implications for involvement of iron in neurodegeneration. Annals of the New York Academy of Sciences, 2004, Volume: 1012 Topics: Animals; Animals, Newborn; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Avian Proteins; Basigin; Behavior, Animal; Blood Glucose; Blood Proteins; Body Weight; Brain; Brain Chemistry; Cell Count; Dietary Supplements; Disease Models, Animal; Hematocrit; Immunohistochemistry; Iron; Iron Deficiencies; Kainic Acid; Male; Membrane Glycoproteins; Microglia; Nerve Degeneration; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Silver Staining; Zinc	2004
Expression, interaction, and proteolysis of death-associated protein kinase and p53 within vulnerable and resistant hippocampal subfields following seizures. Hippocampus, 2004, Volume: 14, Issue:3 Topics: Animals; Apoptosis Regulatory Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Cell Death; Cell Nucleus; Death-Associated Protein Kinases; Denervation; Disease Models, Animal; Functional Laterality; Hippocampus; Immunity, Innate; Kainic Acid; Male; Nerve Degeneration; Neurons; Nuclear Proteins; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Rats; Rats, Sprague-Dawley; Seizures; Tumor Suppressor Protein p53	2004
Over expression of ATF-3 protects rat hippocampal neurons from in vivo injection of kainic acid. Brain research. Molecular brain research, 2004, May-19, Volume: 124, Issue:2 Topics: Activating Transcription Factor 3; Animals; Apoptosis; Cytoprotection; Hippocampus; Immunity, Innate; Kainic Acid; Nerve Degeneration; Neurons; Oxidative Stress; Rats; Transcription Factors	2004
Reciprocal changes of CD44 and GAP-43 expression in the dentate gyrus inner molecular layer after status epilepticus in mice. Experimental neurology, 2004, Volume: 188, Issue:1 Topics: Animals; Dentate Gyrus; Disease Models, Animal; Epilepsy, Temporal Lobe; GAP-43 Protein; Growth Cones; Hyaluronan Receptors; Immunohistochemistry; Kainic Acid; Mice; Mossy Fibers, Hippocampal; Nerve Degeneration; Neuronal Plasticity; Neuropeptide Y; Pilocarpine; Status Epilepticus; Up-Regulation	2004
Modulation of IL-1 beta gene expression by lipid peroxidation inhibition after kainic acid-induced rat brain injury. Experimental neurology, 2004, Volume: 188, Issue:1 Topics: Animals; Behavior, Animal; Benzofurans; Brain Edema; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Gene Expression Regulation; Glutathione; Hippocampus; Interleukin-1; Kainic Acid; Lipid Peroxidation; Male; Malondialdehyde; Nerve Degeneration; Neurotoxins; Oxidative Stress; Rats; Rats, Sprague-Dawley; RNA, Messenger; Seizures	2004
Monocyte chemoattractant protein-1 and macrophage inflammatory protein-2 are involved in both excitotoxin-induced neurodegeneration and regeneration. Experimental cell research, 2004, Jul-01, Volume: 297, Issue:1 Topics: Animals; Apoptosis; Astrocytes; Cell Line, Transformed; Cell Survival; Chemokine CCL2; Chemokine CXCL2; Culture Media, Conditioned; Disease Models, Animal; Encephalitis; Enzyme Inhibitors; Fibroblast Growth Factor 2; Hippocampus; Kainic Acid; Macrophages; Male; Monokines; Nerve Degeneration; Nerve Regeneration; Neurodegenerative Diseases; Neurons; Neurotoxins; Rats; Rats, Inbred F344; Up-Regulation	2004
Genetic control of sensitivity to hippocampal cell death induced by kainic acid: a quantitative trait loci analysis. The Journal of comparative neurology, 2004, Sep-06, Volume: 477, Issue:1 Topics: Animals; Behavior, Animal; Cell Count; Cell Death; Chromosome Mapping; Crosses, Genetic; Excitatory Amino Acid Agonists; Female; Genetic Linkage; Genetic Predisposition to Disease; Genotype; Hippocampus; Histocytochemistry; Kainic Acid; Male; Mice; Mice, Inbred Strains; Nerve Degeneration; Neurons; Phenotype; Quantitative Trait Loci; Seizures	2004
Nestin expression in hippocampal astrocytes after injury depends on the age of the hippocampus. Glia, 2004, Volume: 47, Issue:4 Topics: Aging; Animals; Astrocytes; Denervation; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Hippocampus; Intermediate Filament Proteins; Kainic Acid; Male; Nerve Degeneration; Nerve Tissue Proteins; Nestin; Rats; Rats, Inbred F344; S100 Proteins	2004
Neuropathology of seizures in the immature rabbit. Brain research. Developmental brain research, 2004, Sep-17, Volume: 152, Issue:2 Topics: Animals; Animals, Newborn; Brain Damage, Chronic; Convulsants; Disease Models, Animal; Fever; Hypotension; Kainic Acid; Muscarinic Agonists; Nerve Degeneration; Neurons; Pilocarpine; Prosencephalon; Rabbits; Seizures	2004
Neuronal toxicity in Caenorhabditis elegans from an editing site mutant in glutamate receptor channels. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Sep-15, Volume: 24, Issue:37 Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Animals, Genetically Modified; Arginine; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcium; Calcium Channels; Calreticulin; Congenital Abnormalities; Endoplasmic Reticulum; Genotype; Glutamine; Ion Transport; Kainic Acid; Mammals; Mice; Molecular Sequence Data; Necrosis; Nerve Degeneration; Neurons; Phenotype; Receptor Cross-Talk; Receptors, AMPA; Receptors, Glutamate; RNA Editing; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship; Synaptic Transmission; Touch; Vesicular Glutamate Transport Proteins	2004
Glial expression of the 90-kDa heat shock protein (HSP90) and the 94-kDa glucose-regulated protein (GRP94) following an excitotoxic lesion in the mouse hippocampus. Glia, 2004, Nov-15, Volume: 48, Issue:3 Topics: Animals; Antioxidants; Astrocytes; Biomarkers; Calcium-Binding Proteins; Encephalitis; Glial Fibrillary Acidic Protein; Gliosis; Hippocampus; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Injections, Intraventricular; Kainic Acid; Male; Membrane Proteins; Mice; Mice, Inbred ICR; Microfilament Proteins; Microglia; Nerve Degeneration; Neuroglia; Neurotoxins; Oxidative Stress; Pyramidal Cells	2004
Increased microglial activation and astrogliosis after intranasal administration of kainic acid in C57BL/6 mice. Journal of neurobiology, 2005, Feb-05, Volume: 62, Issue:2 Topics: Animals; Antigens, CD; Antigens, Differentiation; Blotting, Western; Brain; Cell Count; Excitatory Amino Acid Agonists; fas Receptor; Flow Cytometry; Glial Fibrillary Acidic Protein; Gliosis; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Microglia; Nerve Degeneration; Time Factors	2005
IL-12p35 deficiency alleviates kainic acid-induced hippocampal neurodegeneration in C57BL/6 mice. Neurobiology of disease, 2004, Volume: 17, Issue:2 Topics: Animals; Brain; Excitatory Amino Acid Agonists; fas Receptor; Glial Fibrillary Acidic Protein; Hippocampus; Interleukin-12; Interleukin-12 Subunit p35; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Nerve Degeneration; Protein Subunits	2004
p21(WAF1/Cip1) is not involved in kainic acid-induced apoptosis in murine cerebellar granule cells. Brain research, 2004, Dec-31, Volume: 1030, Issue:2 Topics: Animals; Apoptosis; Benzodiazepines; Cell Cycle; Cell Cycle Proteins; Cells, Cultured; Cerebellum; Cyclin-Dependent Kinase Inhibitor p21; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Neurons; Quinoxalines; Receptors, AMPA	2004
Organotypic brain slice cultures: an efficient and reliable method for neurotoxicological screening and mechanistic studies. Alternatives to laboratory animals : ATLA, 2004, Volume: 32, Issue:4 Topics: Animal Testing Alternatives; Animals; Brain; Cell Death; Glutamic Acid; Hippocampus; Kainic Acid; Microscopy, Fluorescence; Nerve Degeneration; Neurons; Neurotoxins; Organ Culture Techniques; Propidium; Rats; Rats, Wistar; Toxicity Tests	2004
Increased susceptibility of glutathione peroxidase-1 transgenic mice to kainic acid-related seizure activity and hippocampal neuronal cell death. Experimental neurology, 2005, Volume: 192, Issue:1 Topics: Animals; Cell Death; Cells, Cultured; Disease Models, Animal; Epilepsy; Genetic Predisposition to Disease; Glutathione Disulfide; Glutathione Peroxidase; Hippocampus; Kainic Acid; Mice; Mice, Transgenic; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Organ Culture Techniques; Oxidative Stress; Receptors, N-Methyl-D-Aspartate; Up-Regulation	2005
Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons. Brain research, 2005, Feb-21, Volume: 1035, Issue:1 Topics: Animals; Astrocytes; Brain; Fluoresceins; Fluorescent Dyes; Glial Fibrillary Acidic Protein; Immunohistochemistry; Indoles; Kainic Acid; Male; Nerve Degeneration; Nitro Compounds; Organic Chemicals; Propionates; Rats; Rats, Sprague-Dawley; Staining and Labeling	2005
Cough and laryngeal muscle discharges in brainstem lesioned anaesthetized cats. Physiological research, 2005, Volume: 54, Issue:6 Topics: Anesthesia; Animals; Brain Stem; Cats; Cough; Electromyography; Kainic Acid; Laryngeal Muscles; Laryngeal Nerves; Medulla Oblongata; Nerve Degeneration; Physical Stimulation; Pons; Raphe Nuclei; Respiratory Center; Respiratory Muscles	2005
Characterization of cell proliferation in the adult dentate under normal conditions and after kainate induced seizures using ribonucleotide reductase and BrdU. Brain research, 2005, Mar-02, Volume: 1036, Issue:1-2 Topics: Animals; Astrocytes; Biomarkers; Bromodeoxyuridine; Caspase 3; Caspases; Cell Death; Cell Proliferation; Convulsants; Dentate Gyrus; Epilepsy; Fluorescent Antibody Technique; Kainic Acid; Male; Nerve Degeneration; Nerve Regeneration; Neuronal Plasticity; Neurons; Rats; Rats, Sprague-Dawley; Recovery of Function; Ribonucleotide Reductases; Stem Cells; Up-Regulation	2005
Endogenous brain-derived neurotrophic factor protects dopaminergic nigral neurons against transneuronal degeneration induced by striatal excitotoxic injury. Brain research. Molecular brain research, 2005, Mar-24, Volume: 134, Issue:1 Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Blotting, Northern; Brain Injuries; Brain-Derived Neurotrophic Factor; Cell Count; Corpus Striatum; Diagnostic Imaging; Dopamine; Electrophoretic Mobility Shift Assay; Functional Laterality; Gene Expression Regulation, Developmental; Immunoglobulin G; Immunohistochemistry; In Situ Hybridization; Kainic Acid; Male; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Receptor, trkB; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase	2005
Exercise, but not environmental enrichment, improves learning after kainic acid-induced hippocampal neurodegeneration in association with an increase in brain-derived neurotrophic factor. Behavioural brain research, 2005, Apr-15, Volume: 159, Issue:1 Topics: Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Environment; Exploratory Behavior; Hippocampus; Housing, Animal; Kainic Acid; Learning; Male; Motor Activity; Nerve Degeneration; Neurons; Neurotoxins; Physical Conditioning, Animal; Rats; Rats, Wistar; Spatial Behavior	2005
Immunohistochemical localization of P-glycoprotein in rat brain and detection of its increased expression by seizures are sensitive to fixation and staining variables. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2005, Volume: 53, Issue:4 Topics: Acetone; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Fixatives; Formaldehyde; Freeze Drying; Frozen Sections; Hydrogen-Ion Concentration; Immunohistochemistry; Kainic Acid; Male; Nerve Degeneration; Polymers; Rats; Rats, Wistar; Seizures; Staining and Labeling; Tissue Fixation	2005
Neuronal and glial expression of the adhesion molecule TAG-1 is regulated after peripheral nerve lesion or central neurodegeneration of adult nervous system. The European journal of neuroscience, 2005, Volume: 21, Issue:5 Topics: Animals; Animals, Newborn; Blotting, Western; Cell Adhesion Molecules, Neuronal; Cells, Cultured; Contactin 2; DNA-Binding Proteins; Early Growth Response Protein 2; Female; Ganglia, Spinal; Gene Expression Regulation, Developmental; Immunohistochemistry; In Situ Hybridization; Indoles; Kainic Acid; Microtubule-Associated Proteins; Nerve Degeneration; Neuroglia; Neurons; Rats; Rats, Wistar; RNA, Messenger; S100 Proteins; Schwann Cells; Sciatic Neuropathy; Spinal Cord; Transcription Factors	2005
The p53-independent nuclear translocation of cyclin G1 in degenerating neurons by ischemic and traumatic insults. Experimental neurology, 2005, Volume: 193, Issue:2 Topics: Animals; Brain Injuries; Brain Ischemia; Cell Death; Cells, Cultured; Cyclin G; Cyclin G1; Cyclins; Cycloheximide; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Fluoresceins; Fluorescent Dyes; Gene Expression Regulation; Gerbillinae; Immunohistochemistry; In Situ Hybridization; In Situ Nick-End Labeling; Kainic Acid; Mice; Mice, Knockout; Microscopy, Immunoelectron; N-Methylaspartate; Nerve Degeneration; Neurons; Organic Chemicals; Phosphopyruvate Hydratase; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Time Factors; Tumor Suppressor Protein p53	2005
Combining exercise and cyclooxygenase-2 inhibition does not ameliorate learning deficits after brain insult, despite an increase in BDNF levels. Brain research, 2005, Jun-07, Volume: 1046, Issue:1-2 Topics: Analysis of Variance; Animals; Brain Damage, Chronic; Brain-Derived Neurotrophic Factor; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Exploratory Behavior; Kainic Acid; Male; Maze Learning; Nerve Degeneration; Physical Conditioning, Animal; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Sulfonamides	2005
Epileptogenesis and chronic seizures in a mouse model of temporal lobe epilepsy are associated with distinct EEG patterns and selective neurochemical alterations in the contralateral hippocampus. Experimental neurology, 2005, Volume: 194, Issue:1 Topics: Action Potentials; Animals; Brain Chemistry; Calbindins; Chronic Disease; Disease Models, Animal; Down-Regulation; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Functional Laterality; Galanin; Hippocampus; Kainic Acid; Mice; Mossy Fibers, Hippocampal; Nerve Degeneration; Neural Pathways; Neuropeptide Y; Neurotoxins; Pyramidal Cells; S100 Calcium Binding Protein G; Sincalide; Status Epilepticus; Theta Rhythm; Up-Regulation	2005
Inflammatory response and glia activation in developing rat hippocampus after status epilepticus. Epilepsia, 2005, Volume: 46 Suppl 5 Topics: Animals; Animals, Newborn; Astrocytes; Blotting, Western; Cytokines; Disease Models, Animal; Gliosis; Hippocampus; Immunohistochemistry; Inflammation; Inflammation Mediators; Interleukin-6; Kainic Acid; Male; Nerve Degeneration; Neuroglia; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Status Epilepticus; Tumor Necrosis Factor-alpha	2005
Novel alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor antagonists of 2,3-benzodiazepine type: chemical synthesis, in vitro characterization, and in vivo prevention of acute neurodegeneration. Journal of medicinal chemistry, 2005, Jul-14, Volume: 48, Issue:14 Topics: Acute Disease; Animals; Benzodiazepines; Binding, Competitive; Brain Infarction; Cells, Cultured; Dioxoles; Hippocampus; In Vitro Techniques; Ischemic Attack, Transient; Kainic Acid; Male; Mice; Nerve Degeneration; Neuroprotective Agents; Patch-Clamp Techniques; Prosencephalon; Radioligand Assay; Rats; Rats, Inbred F344; Receptors, AMPA	2005
Susceptibility to seizure-induced injury and acquired microencephaly following intraventricular injection of saporin-conjugated 192 IgG in developing rat brain. Experimental neurology, 2005, Volume: 194, Issue:2 Topics: Animals; Animals, Newborn; Antibodies, Monoclonal; Atrophy; Basal Nucleus of Meynert; Brain Damage, Chronic; Cholinergic Agents; Convulsants; Disease Models, Animal; Disease Susceptibility; Epilepsy; Excitatory Amino Acid Agonists; Female; Immunotoxins; Injections, Intraventricular; Kainic Acid; Male; N-Glycosyl Hydrolases; Nerve Degeneration; Nerve Growth Factors; Rats; Rats, Sprague-Dawley; Receptor, Nerve Growth Factor; Ribosome Inactivating Proteins, Type 1; Saporins	2005
Pentoxifylline and insulin-like growth factor-I (IGF-I) abrogate kainic acid-induced cognitive impairment in mice. Journal of neuroimmunology, 2005, Volume: 169, Issue:1-2 Topics: Analysis of Variance; Animals; Behavior, Animal; Cognition Disorders; Discrimination Learning; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Fluoresceins; Free Radical Scavengers; Hippocampus; Insulin-Like Growth Factor Binding Protein 1; Kainic Acid; Male; Mice; Mice, Inbred ICR; Motor Activity; Nerve Degeneration; Neurons; Organic Chemicals; Pentoxifylline	2005
Increase in hippocampal cell death after treatment with kainate in zinc deficiency. Neurochemistry international, 2005, Volume: 47, Issue:8 Topics: Animals; Cell Death; Disease Models, Animal; Disease Susceptibility; Epilepsy; Excitatory Amino Acid Agonists; Extracellular Fluid; Food, Formulated; Hippocampus; In Situ Nick-End Labeling; Injections, Intraperitoneal; Kainic Acid; Male; Mice; Nerve Degeneration; Neurotoxins; Pyramidal Cells; Up-Regulation; Zinc	2005
Kainate-induced zinc translocation from presynaptic terminals causes neuronal and astroglial cell death and mRNA loss of BDNF receptors in the hippocampal formation and amygdala. Journal of neuroscience research, 2005, Oct-15, Volume: 82, Issue:2 Topics: Amygdala; Animals; Astrocytes; Brain-Derived Neurotrophic Factor; Cell Death; Chelating Agents; Chlorides; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Presynaptic Terminals; Pyramidal Cells; Rats; Rats, Wistar; Receptor, trkB; RNA, Messenger; Synaptic Transmission; Up-Regulation; Zinc; Zinc Compounds	2005
DNA damage and nonhomologous end joining in excitotoxicity: neuroprotective role of DNA-PKcs in kainic acid-induced seizures. Hippocampus, 2005, Volume: 15, Issue:8 Topics: Animals; Benzothiazoles; Cell Death; Cells, Cultured; DNA Damage; DNA Repair; DNA-Activated Protein Kinase; DNA-Binding Proteins; Entorhinal Cortex; Excitatory Amino Acid Agonists; Heterozygote; Hippocampus; Immunohistochemistry; In Situ Nick-End Labeling; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Mitochondria; Nerve Degeneration; Neurons; Nuclear Proteins; Seizures; Thiazoles; Toluene; Tumor Suppressor Protein p53	2005
Neuroprotective potential of dietary restriction against kainate-induced excitotoxicity in adult male Wistar rats. Brain research bulletin, 2005, Nov-30, Volume: 67, Issue:6 Topics: Animals; Antioxidants; Blotting, Western; Brain; Caloric Restriction; Excitatory Amino Acid Agonists; Glutathione; Glutathione Peroxidase; HSP70 Heat-Shock Proteins; Kainic Acid; Lipid Peroxidation; Male; Nerve Degeneration; Neurons; Oxidoreductases; Rats; Rats, Wistar	2005
Febrile convulsions induced by the combination of lipopolysaccharide and low-dose kainic acid enhance seizure susceptibility, not epileptogenesis, in rats. Epilepsia, 2005, Volume: 46, Issue:12 Topics: Age Factors; Amygdala; Animals; Animals, Newborn; Body Temperature; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Electric Stimulation; Electroencephalography; Epilepsy; Hippocampus; Humans; Kainic Acid; Kindling, Neurologic; Lipopolysaccharides; Male; Nerve Degeneration; Rats; Rats, Sprague-Dawley; Seizures; Seizures, Febrile	2005
Regional neuropathology following kainic acid intoxication in adult and aged C57BL/6J mice. Brain research, 2006, Jan-27, Volume: 1070, Issue:1 Topics: Aging; Animals; Brain; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Hippocampus; Histocytochemistry; Immunoglobulin G; Immunohistochemistry; Kainic Acid; Lectins; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Seizures; Staining and Labeling	2006
Kainic acid dose affects delayed cell death mechanism after status epilepticus. Brain & development, 2007, Volume: 29, Issue:1 Topics: Animals; Caspase 3; Cell Death; Cell Nucleus; Convulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Microscopy, Electron, Transmission; Nerve Degeneration; Neurons; Pyramidal Cells; Rats; Rats, Wistar; Status Epilepticus; Time Factors	2007
Neuronal sensitivity to kainic acid is dependent on the Nrf2-mediated actions of the antioxidant response element. Journal of neurochemistry, 2006, Volume: 98, Issue:6 Topics: Animals; Antioxidants; Disease Susceptibility; Excitatory Amino Acid Agonists; Female; Glial Fibrillary Acidic Protein; Hippocampus; Kainic Acid; Male; Mice; Mice, Knockout; Mice, Transgenic; Microglia; Nerve Degeneration; Neurons; Neurotoxins; NF-E2-Related Factor 2; Oligonucleotide Array Sequence Analysis; Response Elements; Seizures	2006
Comparison of seizure phenotype and neurodegeneration induced by systemic kainic acid in inbred, outbred, and hybrid mouse strains. The European journal of neuroscience, 2006, Volume: 24, Issue:8 Topics: Animals; Cell Count; Dentate Gyrus; Drug Resistance; Excitatory Amino Acid Agonists; Fluoresceins; Fluorescent Dyes; Hybridization, Genetic; Kainic Acid; Male; Mice; Mice, Inbred Strains; Mossy Fibers, Hippocampal; Nerve Degeneration; Organic Chemicals; Phenotype; Quinolinic Acid; Seizures; Species Specificity	2006
Enhanced hippocampal neurodegeneration after traumatic or kainate excitotoxicity in GFAP-null mice. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2006, Volume: 13, Issue:9 Topics: Animals; Astrocytes; Brain Injuries; Cell Communication; Cell Survival; Cytoprotection; Disease Models, Animal; Drug Resistance; Glial Fibrillary Acidic Protein; Hippocampus; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Neurotoxins; Pyramidal Cells; Recovery of Function; Seizures; Up-Regulation	2006
Expression, activity, and role of serine palmitoyltransferase in the rat hippocampus after kainate injury. Journal of neuroscience research, 2007, Feb-01, Volume: 85, Issue:2 Topics: Animals; Antimetabolites; Astrocytes; Blotting, Western; Ceramides; Cycloserine; Excitatory Amino Acid Agonists; Fatty Acids, Monounsaturated; Hippocampus; Immunohistochemistry; Kainic Acid; Nerve Degeneration; Organ Culture Techniques; Rats; Rats, Wistar; Serine C-Palmitoyltransferase; Spectrometry, Mass, Electrospray Ionization	2007
Bioluminescence imaging of Smad signaling in living mice shows correlation with excitotoxic neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America, 2006, Nov-28, Volume: 103, Issue:48 Topics: Animals; Biomarkers; Cells, Cultured; Central Nervous System; Dizocilpine Maleate; Genes, Reporter; Kainic Acid; Mice; Microscopy, Confocal; Nerve Degeneration; Signal Transduction; Smad Proteins	2006
Differential susceptibility to striatal neurodegeneration induced by quinolinic acid and kainate in inbred, outbred and hybrid mouse strains. The European journal of neuroscience, 2006, Volume: 24, Issue:11 Topics: Animals; Chimera; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance; Genetic Predisposition to Disease; Huntington Disease; Kainic Acid; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Mice, Inbred ICR; Nerve Degeneration; Neurons; Neurotoxins; Phenotype; Quinolinic Acid; Species Specificity	2006
A pathogenetic hypothesis of Unverricht-Lundborg disease onset and progression. Neurobiology of disease, 2007, Volume: 25, Issue:3 Topics: Animals; Cystatin B; Cystatins; Disease Models, Animal; Disease Progression; Electrophysiology; Epilepsies, Myoclonic; Excitatory Amino Acid Agonists; Genetic Predisposition to Disease; Hippocampus; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Nerve Degeneration; Neurons; Organ Culture Techniques; Unverricht-Lundborg Syndrome	2007
Kainic acid induces early and transient autophagic stress in mouse hippocampus. Neuroscience letters, 2007, Feb-27, Volume: 414, Issue:1 Topics: Animals; Autophagy; Autophagy-Related Protein 5; Biomarkers; Epilepsy; Hippocampus; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Molecular Chaperones; Nerve Degeneration; Neurotoxins; Oncogene Protein v-akt; Stress, Physiological; Ubiquitins; Up-Regulation	2007
Morphological changes in the hippocampus following nicotine and kainic acid administration. Physiological research, 2007, Volume: 56, Issue:5 Topics: Animals; Benzimidazoles; Excitatory Amino Acid Agonists; Fluoresceins; Fluorescent Dyes; Hippocampus; Injections, Intraperitoneal; Kainic Acid; Male; NADPH Dehydrogenase; Nerve Degeneration; Neurons; Nicotine; Nicotinic Agonists; Organic Chemicals; Rats; Rats, Wistar; Staining and Labeling	2007
IL-18 deficiency aggravates kainic acid-induced hippocampal neurodegeneration in C57BL/6 mice due to an overcompensation by IL-12. Experimental neurology, 2007, Volume: 205, Issue:1 Topics: Adaptation, Physiological; Animals; Astrocytes; Female; Gliosis; Hippocampus; Interferon-gamma; Interleukin-12; Interleukin-18; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Motor Activity; Nerve Degeneration; Recombinant Proteins; Severity of Illness Index	2007
Kainic acid and nitrergic neurons in immature hippocampus. Prague medical report, 2006, Volume: 107, Issue:4 Topics: Animals; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; NADPH Dehydrogenase; Nerve Degeneration; Nitrergic Neurons; Rats; Rats, Wistar	2006
Induction of the Wnt inhibitor, Dickkopf-1, is associated with neurodegeneration related to temporal lobe epilepsy. Epilepsia, 2007, Volume: 48, Issue:4 Topics: Animals; Cell Death; Disease Models, Animal; Epilepsy, Temporal Lobe; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Kainic Acid; Lithium Compounds; Male; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Sclerosis; Wnt Proteins	2007
Nitric oxide synthase isoforms undertake unique roles during excitotoxicity. Stroke, 2007, Volume: 38, Issue:6 Topics: Animals; Blood-Brain Barrier; Excitatory Amino Acid Agonists; Isoenzymes; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III	2007
Sequential expression of cell-cycle regulators and Alzheimer's disease-related proteins in entorhinal cortex after hippocampal excitotoxic damage. Journal of neuroscience research, 2007, Volume: 85, Issue:8 Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antibodies, Monoclonal; Biomarkers; Cell Cycle; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Cyclins; Dentate Gyrus; Entorhinal Cortex; Epitopes; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Nerve Tissue Proteins; Phosphorylation; Rats; Rats, Wistar; tau Proteins; Time Factors	2007
Changes in pigment epithelium-derived factor expression following kainic acid induced cerebellar lesion in rat. Neuroscience letters, 2007, Aug-31, Volume: 424, Issue:1 Topics: Animals; Astrocytes; Calbindins; Cerebellar Diseases; Cerebellum; Eye Proteins; Glial Fibrillary Acidic Protein; Gliosis; Immunohistochemistry; In Situ Hybridization, Fluorescence; Kainic Acid; Male; Microglia; Nerve Degeneration; Nerve Growth Factors; Neurotoxins; Plant Lectins; Purkinje Cells; Rats; Rats, Wistar; RNA, Messenger; S100 Calcium Binding Protein G; Serpins; Up-Regulation	2007
IGF2 knockout mice are resistant to kainic acid-induced seizures and neurodegeneration. Brain research, 2007, Oct-17, Volume: 1175 Topics: Animals; Apoptosis; Brain; Disease Models, Animal; Epilepsy; Genetic Predisposition to Disease; Hippocampus; Insulin-Like Growth Factor II; Kainic Acid; Limbic System; Mice; Mice, Knockout; Nerve Degeneration; Neural Pathways; Neurotoxins; Organ Culture Techniques	2007
Time-dependent changes in distribution of basic fibroblast growth factor immunoreactive cells in hippocampus after kainic acid injection in rat pups. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2007, Volume: 25, Issue:6 Topics: Animals; Animals, Newborn; Astrocytes; Cell Count; Cell Death; Disease Progression; Down-Regulation; Fibroblast Growth Factor 2; Gliosis; Hippocampus; Immunohistochemistry; Kainic Acid; Nerve Degeneration; Neurons; Neurotoxins; Pyramidal Cells; Rats; Rats, Wistar; Seizures; Time Factors	2007
Region-specific differentiation of embryonic stem cell-derived neural progenitor transplants into the adult mouse hippocampus following seizures. Journal of neuroscience research, 2008, Feb-15, Volume: 86, Issue:3 Topics: Animals; Astrocytes; Biomarkers; Cell Differentiation; Cell Movement; Cell Proliferation; Cells, Cultured; Cellular Senescence; Convulsants; Dentate Gyrus; Embryonic Stem Cells; Excitatory Amino Acid Agonists; Fornix, Brain; Hippocampus; Kainic Acid; Mice; Mice, SCID; Nerve Degeneration; Neurons; Oligodendroglia; Sclerosis; Seizures; Stem Cell Transplantation	2008
Microarray profile of seizure damage-refractory hippocampal CA3 in a mouse model of epileptic preconditioning. Neuroscience, 2007, Dec-05, Volume: 150, Issue:2 Topics: Animals; Brain Damage, Chronic; Convulsants; Disease Models, Animal; Down-Regulation; Epilepsy; Excitatory Amino Acid Agonists; Gene Expression; Gene Expression Profiling; Hippocampus; Ischemic Preconditioning; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Nerve Tissue Proteins; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Status Epilepticus; Treatment Outcome; Up-Regulation	2007
A highly sulfated chondroitin sulfate preparation, CS-E, prevents excitatory amino acid-induced neuronal cell death. Journal of neurochemistry, 2008, Volume: 104, Issue:6 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Caspase 3; Cell Death; Cell Survival; Chondroitin Sulfates; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neocortex; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Phosphorylation; Polyelectrolytes; Polymers; Pregnancy; Rats; Rats, Sprague-Dawley; Tyrosine	2008
Increased expression of the lysosomal protease cathepsin S in hippocampal microglia following kainate-induced seizures. Neuroscience letters, 2007, Dec-18, Volume: 429, Issue:2-3 Topics: Animals; Astrocytes; Cathepsins; Coloring Agents; Disease Models, Animal; Enzyme Activation; Epilepsy; Gene Expression Regulation, Enzymologic; Gliosis; Hippocampus; Kainic Acid; Lysosomes; Male; Mice; Mice, Inbred C57BL; Microglia; Nerve Degeneration; Neurotoxins; Nicotine; Nicotinic Agonists; Oligonucleotide Array Sequence Analysis; Pyramidal Cells; Up-Regulation	2007
Neurokinin-3 peptide instead of neurokinin-1 synergistically exacerbates kainic acid-inducing degeneration of neurons in the substantia nigra of mice. Journal of neurochemistry, 2008, Volume: 105, Issue:1 Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Drug Synergism; Fluoresceins; Kainic Acid; Male; Mice; Mice, Inbred Strains; Nerve Degeneration; Nerve Tissue Proteins; Neurokinin-1 Receptor Antagonists; Neurons; Organic Chemicals; Peptide Fragments; Pyrrolidonecarboxylic Acid; Quinolines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Substance P; Substantia Nigra; Tetrazolium Salts; Thiazoles	2008
Calpain activation is involved in early caspase-independent neurodegeneration in the hippocampus following status epilepticus. Journal of neurochemistry, 2008, Volume: 105, Issue:3 Topics: Animals; Calpain; Caspases; Convulsants; Dipeptides; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Epilepsy; Fluoresceins; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Organic Chemicals; Rats; Rats, Wistar; Spectrin; Status Epilepticus; Time Factors	2008
Ablation of p27 enhance kainate-induced seizure and hippocampal degeneration. Neuroreport, 2007, Nov-19, Volume: 18, Issue:17 Topics: Animals; Blotting, Western; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p27; DNA; Excitatory Amino Acid Agonists; Hippocampus; Immunohistochemistry; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Seizures	2007
Role of glutathione peroxidase in the ontogeny of hippocampal oxidative stress and kainate seizure sensitivity in the genetically epilepsy-prone rats. Neurochemistry international, 2008, Volume: 52, Issue:6 Topics: Aging; Animals; Antioxidants; Drug Resistance; Enzyme Activation; Epilepsy; Excitatory Amino Acid Agonists; Genetic Predisposition to Disease; Glutathione; Glutathione Peroxidase; Hippocampus; Kainic Acid; Lipid Peroxidation; Male; Nerve Degeneration; Neuroglia; Neurotoxins; Oxidative Stress; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxide Dismutase-1	2008
Kainate-induced mitochondrial oxidative stress contributes to hippocampal degeneration in senescence-accelerated mice. Cellular signalling, 2008, Volume: 20, Issue:4 Topics: Aging, Premature; Animals; Caspase 3; Cytochromes c; Disease Models, Animal; Enzyme Activation; Glutathione; Glutathione Disulfide; Hippocampus; Ion Channels; Kainic Acid; Lipid Peroxidation; Lipofuscin; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred Strains; Mitochondria; Mitochondrial Proteins; Nerve Degeneration; Neurons; Oxidation-Reduction; Oxidative Stress; Proteins; Proto-Oncogene Proteins c-fos; Seizures; Superoxide Dismutase; Time Factors; Uncoupling Protein 2	2008
Manganese enhanced MRI detects mossy fiber sprouting rather than neurodegeneration, gliosis or seizure-activity in the epileptic rat hippocampus. NeuroImage, 2008, May-01, Volume: 40, Issue:4 Topics: Algorithms; Animals; Blood-Brain Barrier; Chlorides; Chronic Disease; Contrast Media; Data Interpretation, Statistical; Dentate Gyrus; Electroencephalography; Epilepsy; Excitatory Amino Acid Agonists; Gadolinium; Gliosis; Kainic Acid; Magnetic Resonance Imaging; Male; Manganese Compounds; Mossy Fibers, Hippocampal; Nerve Degeneration; Rats; Rats, Wistar; Seizures; Status Epilepticus	2008
Gender differences in susceptibility to kainic acid-induced neurodegeneration in aged C57BL/6 mice. Neurotoxicology, 2008, Volume: 29, Issue:3 Topics: Aging; Animals; Astrocytes; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cell Proliferation; Cerebral Cortex; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Agonists; Female; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nerve Degeneration; Nerve Growth Factors; Seizures; Sex Characteristics	2008
Edaravone prevents kainic acid-induced neuronal death. Brain research, 2008, May-13, Volume: 1209 Topics: Aldehydes; Animals; Antipyrine; Brain; Cell Death; Disease Models, Animal; Down-Regulation; Edaravone; Epilepsy; Free Radical Scavengers; Glutathione; Kainic Acid; Lipid Peroxidation; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Rats; Rats, Sprague-Dawley; Status Epilepticus; Treatment Outcome	2008
CREB has a context-dependent role in activity-regulated transcription and maintains neuronal cholesterol homeostasis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008, Volume: 22, Issue:8 Topics: Animals; Base Sequence; Cholesterol; Corpus Striatum; Cyclic AMP Response Element Modulator; Cyclic AMP Response Element-Binding Protein; Female; Gene Expression Profiling; Hippocampus; Homeostasis; Kainic Acid; Male; Mice; Mice, Knockout; Mice, Transgenic; Nerve Degeneration; Neuronal Plasticity; Neurons; Oligonucleotide Array Sequence Analysis; RNA Interference; RNA, Small Interfering; Signal Transduction; Transcription, Genetic	2008
Characterization and localization of adenosine receptors in rat spinal cord. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1984, Volume: 4, Issue:9 Topics: Adenosine; Animals; Autoradiography; Binding Sites; Kainic Acid; Male; Nerve Degeneration; Rats; Receptors, Cell Surface; Receptors, Purinergic; Spinal Cord; Tissue Distribution	1984
Effect of systemic and intrastriatal injections of haloperidol on striatal dopamine and DOPAC concentrations in rats pretreated by section of nigrostriatal fibres. The Journal of pharmacy and pharmacology, 1980, Volume: 32, Issue:7 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Feedback; Glutamate Decarboxylase; Haloperidol; Kainic Acid; Male; Nerve Degeneration; Phenylacetates; Rats; Receptors, Dopamine; Substantia Nigra	1980
Kainic acid neurotoxicity; effect of systemic injection on neurotransmitter markers in different brain regions. Brain research, 1981, Dec-28, Volume: 230, Issue:1-2 Topics: Amygdala; Animals; Brain; Choline O-Acetyltransferase; Corpus Striatum; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Hippocampus; Injections, Subcutaneous; Kainic Acid; Male; Nerve Degeneration; Neurons; Neurotransmitter Agents; Pyrrolidines; Rats; Rats, Inbred Strains; Septum Pellucidum; Thalamus	1981
Investigations into the mechanism of excitant amino acid cytotoxicity using a well-characterized glutamatergic system. Brain research, 1983, Mar-14, Volume: 263, Issue:1 Topics: Animals; Aspartic Acid; Concanavalin A; Cysteine; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Grasshoppers; Kainic Acid; Nerve Degeneration; Neuromuscular Junction; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Receptors, Cell Surface; Receptors, Glutamate; Synaptic Transmission	1983
Kainic acid induced seizures: neurochemical and histopathological changes. Neuroscience, 1983, Volume: 10, Issue:4 Topics: Amygdala; Animals; Behavior, Animal; Brain; Cerebral Cortex; Corpus Striatum; Hippocampus; Kainic Acid; Limbic System; Male; Microscopy, Electron; Nerve Degeneration; Neurons; Neurotransmitter Agents; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Synaptic Transmission	1983
Substantia nigra cell death from kainic acid or folic acid injections into the pontine tegmentum. Brain research, 1984, Apr-30, Volume: 298, Issue:2 Topics: Afferent Pathways; Animals; Cell Survival; Choline O-Acetyltransferase; Cholinergic Fibers; Dopamine; Folic Acid; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Kainic Acid; Male; Nerve Degeneration; Pons; Pyrrolidines; Rats; Rats, Inbred Strains; Substantia Nigra; Tyrosine 3-Monooxygenase	1984
Local and distant neuronal degeneration following intrastriatal injection of kainic acid. Journal of neuropathology and experimental neurology, 1980, Volume: 39, Issue:3 Topics: Amygdala; Animals; Astrocytes; Axonal Transport; Axons; Cerebral Cortex; Corpus Striatum; Dominance, Cerebral; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Neural Pathways; Neurons; Pyrrolidines; Rats; Substantia Nigra; Thalamus	1980
Spinal neurons mediate return of substance P following deafferentation of cat spinal cord. Brain research, 1981, Dec-28, Volume: 230, Issue:1-2 Topics: Afferent Pathways; Animals; Cats; Ganglia, Spinal; Kainic Acid; Nerve Degeneration; Nerve Fibers; Nerve Regeneration; Neurons; Spinal Cord; Substance P	1981
Studies of effects of kainic acid lesions in the dorsal lateral geniculate nucleus of rat. The Journal of comparative neurology, 1982, Oct-10, Volume: 211, Issue:1 Topics: Animals; Aspartic Acid; Autoradiography; Axonal Transport; Evoked Potentials, Visual; Female; Geniculate Bodies; Kainic Acid; Microscopy, Fluorescence; Nerve Degeneration; Nerve Fibers; Neurons; Pyrrolidines; Rats; Rats, Inbred Strains; Superior Colliculi; Synaptic Transmission; Visual Cortex; Visual Pathways	1982
The effects of intraocular injection of kainic acid on the synaptic organization of the goldfish retina. Brain research, 1980, Jan-27, Volume: 182, Issue:2 Topics: Animals; Axons; Dendrites; Dose-Response Relationship, Drug; Glutamates; Goldfish; Kainic Acid; Nerve Degeneration; Neurons; Photoreceptor Cells; Pyrrolidines; Receptors, Neurotransmitter; Retina; Synapses; Visual Pathways	1980
Sustained limbic seizures induced by intraamygdaloid kainic acid in the baboon: Symptomatology and neuropathological consequences. Annals of neurology, 1980, Volume: 8, Issue:5 Topics: Amygdala; Animals; Cerebral Cortex; Electroencephalography; Evoked Potentials; Kainic Acid; Limbic System; Nerve Degeneration; Papio; Pyrrolidines; Seizures; Synaptic Transmission	1980
Effects of neuronal activity on kainic acid neurotoxicity in the ventral cochlear nucleus. Neuroscience letters, 1980, Volume: 20, Issue:2 Topics: Acoustic Stimulation; Animals; Brain Stem; Cochlear Nerve; Guinea Pigs; Kainic Acid; Nerve Degeneration; Neurons; Pyrrolidines; Synaptic Transmission	1980
Comparative toxicity of kainic acid and other acidic amino acids toward rat hippocampal neurons. Neuroscience, 1981, Volume: 6, Issue:12 Topics: Amino Acids; Animals; Dose-Response Relationship, Drug; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Membrane Potentials; Nerve Degeneration; Neurons; Pyrrolidines; Rats; Rats, Inbred Strains; Synaptic Transmission	1981
A comparative histological and electrophysiological study of some neurotoxins in the rat hippocampus. The Journal of comparative neurology, 1982, Oct-20, Volume: 211, Issue:2 Topics: Afferent Pathways; Animals; Cycloleucine; Dose-Response Relationship, Drug; Evoked Potentials; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Neurons; Neurotoxins; Rats; Rats, Inbred Strains; Seizures; Synaptic Transmission	1982
Activation pattern in the prefrontal system of kainic acid-pretreated rats. Acta neurobiologiae experimentalis, 1982, Volume: 42, Issue:2 Topics: Animals; Frontal Lobe; Kainic Acid; Male; Nerve Degeneration; Pyrrolidines; Rats; Rats, Inbred Strains; Synaptic Transmission	1982
The organotypic tissue culture model of corticostriatal system used for examining amino acid neurotoxicity and its antagonism: studies on kainic acid, quinolinic acid and (-) 2-amino-7-phosphonoheptanoic acid. Journal of neural transmission. Supplementum, 1983, Volume: 19 Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Amino Acids; Animals; Caudate Nucleus; Corpus Striatum; Culture Techniques; Dose-Response Relationship, Drug; Frontal Lobe; Kainic Acid; Microscopy, Electron; Models, Neurological; Nerve Degeneration; Pyridines; Pyrrolidines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission	1983
Anterograde and transsynaptic degeneration 'en cascade' in basal ganglia induced by intrastriatal injection of kainic acid: an animal analogue of Huntington's disease. Brain research, 1980, Aug-25, Volume: 196, Issue:1 Topics: Acetylcholinesterase; Animals; Basal Ganglia; Corpus Striatum; Disease Models, Animal; Female; Globus Pallidus; Huntington Disease; Kainic Acid; Male; Nerve Degeneration; Neurons; Pyrrolidines; Rats; Substantia Nigra; Synapses	1980
Sulfate conjugation of dopamine in rat brain: regional distribution of activity and evidence for neuronal localization. Journal of neurochemistry, 1984, Volume: 42, Issue:5 Topics: Animals; Arylsulfotransferase; Brain; Cerebellum; Corpus Striatum; Dopamine; Kainic Acid; Kinetics; Male; Nerve Degeneration; Neurons; Rats; Rats, Inbred Strains; Sulfurtransferases; Tissue Distribution	1984
Kainic acid induces sprouting of retinal neurons. Science (New York, N.Y.), 1984, Feb-03, Volume: 223, Issue:4635 Topics: Animals; Cats; Dendrites; Dose-Response Relationship, Drug; Kainic Acid; Nerve Degeneration; Neurons; Pyrrolidines; Rabbits; Retina	1984
Effects of atropine, pilocarpine and morphine on footshock-induced aggressive behaviour in rats after lesion of hippocampal pyramidal cells with kainic acid. Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina, 1982, Volume: 37 Topics: Aggression; Animals; Atropine; Drug Interactions; Electroshock; Hippocampus; Humans; Kainic Acid; Male; Morphine; Nerve Degeneration; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Cholinergic	1982
Evidence against an exclusive role of glutamate in kainic acid neurotoxicity. Neuroscience letters, 1980, Oct-02, Volume: 19, Issue:3 Topics: Animals; Choline O-Acetyltransferase; Glutamates; Granulocytes; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Nerve Degeneration; Pyrrolidines; Rats	1980
Morphological studies on neuroglia. II. Response of glial cells to kainic acid-induced lesions. Cell and tissue research, 1981, Volume: 216, Issue:3 Topics: Animals; Astrocytes; Cell Nucleus; Cytoskeleton; Hippocampus; Kainic Acid; Macrophages; Microscopy, Electron; Nerve Degeneration; Neuroglia; Oligodendroglia; Organoids; Pyrrolidines; Rats	1981
Fate of the hippocampal mossy fiber projection after destruction of its postsynaptic targets with intraventricular kainic acid. The Journal of comparative neurology, 1981, Mar-10, Volume: 196, Issue:4 Topics: Afferent Pathways; Animals; Axons; Dendrites; Hippocampus; Kainic Acid; Male; Microscopy, Electron; Nerve Degeneration; Nerve Fibers; Nerve Regeneration; Pyrrolidines; Rats; Synapses; Synaptic Vesicles	1981
The effect of small doses of kainic acid on the area CA3 of the hippocampal formation. An electron microscopic study. Archivum histologicum Japonicum = Nihon soshikigaku kiroku, 1981, Volume: 44, Issue:2 Topics: Animals; Axons; Dendrites; Hippocampus; Kainic Acid; Male; Microscopy, Electron; Nerve Degeneration; Nerve Endings; Neuroglia; Neurons; Pyrrolidines; Rats; Rats, Inbred Strains	1981
Recovery of function after neurotoxic damage to the hippocampal CA3 region: importance of postoperative recovery interval and task experience. Behavioral and neural biology, 1981, Volume: 33, Issue:4 Topics: Animals; Choice Behavior; Conditioning, Operant; Discrimination Learning; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Nerve Regeneration; Neurons; Orientation; Pyrrolidines; Rats; Rats, Inbred Strains; Retention, Psychology; Time Factors	1981
A fine structural and histochemical study on the effect of kainic acid on cultured neostriatal cells. Brain research, 1980, Jan-06, Volume: 181, Issue:1 Topics: Acetylcholinesterase; Animals; Corpus Striatum; Culture Techniques; Kainic Acid; Microscopy, Electron, Scanning; Nerve Degeneration; Nerve Fibers; Neurons; Pyrrolidines; Rats	1980
Diminished responses of nigral dopaminergic neurons to haloperidol and morphine following lesions in the striatum. Brain research, 1980, Jan-06, Volume: 181, Issue:1 Topics: Animals; Corpus Striatum; Dopamine; Evoked Potentials; Haloperidol; Kainic Acid; Male; Morphine; Nerve Degeneration; Neural Pathways; Neurons; Rats; Receptors, Dopamine; Substantia Nigra	1980
Selective reinnervation of hippocampal area CA1 and the fascia dentata after destruction of CA3-CA4 afferents with kainic acid. Brain research, 1980, Jan-20, Volume: 182, Issue:1 Topics: Afferent Pathways; Animals; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Nerve Degeneration; Nerve Fibers; Nerve Regeneration; Neurons; Rats; Septum Pellucidum	1980
Kainate-induced lesion in the optic tectum: dependency upon optic nerve afferents or glutamate. Brain research, 1980, Apr-07, Volume: 187, Issue:1 Topics: Animals; Columbidae; Glutamates; Kainic Acid; Nerve Degeneration; Neurons; Optic Nerve; Pyrrolidines; Retina; Visual Cortex; Visual Pathways	1980
Interconnection of GABA-ergic neurons in rat extrapyramidal tract: analysis using intracerebral microinjection of kainic acid. Experimental neurology, 1980, Volume: 68, Issue:1 Topics: 4-Aminobutyrate Transaminase; Animals; Cerebral Cortex; Corpus Striatum; Electrolytes; Extrapyramidal Tracts; gamma-Aminobutyric Acid; Globus Pallidus; Glutamate Decarboxylase; Kainic Acid; Male; Motor Activity; Nerve Degeneration; Neurons; Pyrrolidines; Rats; Substantia Nigra; Succinate Dehydrogenase	1980
Degeneration of hippocampal CA3 pyramidal cells induced by intraventricular kainic acid. The Journal of comparative neurology, 1980, Jul-15, Volume: 192, Issue:2 Topics: Animals; Axons; Dendrites; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Nerve Degeneration; Neuroglia; Neurons; Pyrrolidines; Rats; Synapses	1980
Different sensitivity of hippocampal neurons to kainic acid in the rabbit. Neuroscience, 1980, Volume: 5, Issue:8 Topics: Animals; Dose-Response Relationship, Drug; Glutamates; Hippocampus; Kainic Acid; Nerve Degeneration; Neurons; Pyrrolidines; Rabbits	1980
Excitotoxic degeneration is initiated at non-random sites in cultured rat cerebellar neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:11 Topics: Animals; Calcium; Cells, Cultured; Cerebellum; Excitatory Amino Acid Agonists; Intracellular Membranes; Ions; Kainic Acid; Membrane Potentials; Mitochondria; Nerve Degeneration; Neurites; Neurons; Osmolar Concentration; Purkinje Cells; Rats; Sodium	1995
Neurotoxicity of acromelic acid in cultured neurons from rat spinal cord. Neuroscience, 1995, Volume: 68, Issue:2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cells, Cultured; Kainic Acid; L-Lactate Dehydrogenase; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neurotoxins; Rats; Rats, Wistar; Spinal Cord	1995
Glutamate-mediated excitotoxic death of cultured striatal neurons is mediated by non-NMDA receptors. Experimental neurology, 1995, Volume: 136, Issue:2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basal Ganglia; Cell Death; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glutamic Acid; Kainic Acid; Nerve Degeneration; Pregnancy; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	1995
Adhesion molecule expression on murine cerebral endothelium following the injection of a proinflammagen or during acute neuronal degeneration. Journal of neurocytology, 1995, Volume: 24, Issue:9 Topics: Animals; Antigens, Differentiation, Myelomonocytic; Brain; Cell Adhesion Molecules; Endothelium, Vascular; Immunohistochemistry; Intercellular Adhesion Molecule-1; Kainic Acid; Kinetics; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Nerve Degeneration; Platelet Endothelial Cell Adhesion Molecule-1; Vascular Cell Adhesion Molecule-1	1995
Neuronal damage induced by beta-N-oxalylamino-L-alanine, in the rat hippocampus, can be prevented by a non-NMDA antagonist, 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline. Brain research, 1993, Nov-05, Volume: 627, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; beta-Alanine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Quinoxalines; Rats; Rats, Wistar	1993
AMPA/kainate receptor-mediated damage to NADPH-diaphorase-containing neurons is Ca2+ dependent. Neuroscience letters, 1994, Feb-14, Volume: 167, Issue:1-2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Kainic Acid; Mice; NADPH Dehydrogenase; Nerve Degeneration; Neurons; Receptors, AMPA; Receptors, Kainic Acid	1994
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline protects against both AMPA and kainate-induced lesions in rat striatum in vivo. Neuroscience, 1994, Volume: 59, Issue:4 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biomarkers; Choline O-Acetyltransferase; Corpus Striatum; Glutamate Decarboxylase; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Nerve Tissue Proteins; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate	1994
Propofol protects cultured rat hippocampal neurons against N-methyl-D-aspartate receptor-mediated glutamate toxicity. Journal of neurosurgical anesthesiology, 1994, Volume: 6, Issue:4 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Neurons; Phosphopyruvate Hydratase; Propofol; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Time Factors	1994
Neuroprotective effect of acidic fibroblast growth factor on seizure-associated brain damage. Neurological research, 1994, Volume: 16, Issue:5 Topics: Animals; Brain; Brain Damage, Chronic; Fibroblast Growth Factor 1; Hippocampus; Kainic Acid; Nerve Degeneration; Organ Specificity; Rats; Rats, Wistar; Recombinant Proteins; Seizures	1994
Changes in expression of glutamate receptor subunits following photoreceptor degeneration in the rd mouse retina. Neuroscience letters, 1995, Jan-02, Volume: 183, Issue:1-2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Gene Expression; In Situ Hybridization; Kainic Acid; Mice; Mice, Inbred C57BL; Nerve Degeneration; Photoreceptor Cells; Receptors, Glutamate; Retina	1995
Interleukin-1 beta attenuates excitatory amino acid-induced neurodegeneration in vitro: involvement of nerve growth factor. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:5 Pt 1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Antibodies, Monoclonal; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acids; Fetus; Glutamic Acid; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Kainic Acid; Kinetics; N-Methylaspartate; Nerve Degeneration; Nerve Growth Factors; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sialoglycoproteins	1995
Ca2+ permeable AMPA/kainate channels permit rapid injurious Ca2+ entry. Neuroreport, 1995, May-30, Volume: 6, Issue:8 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cell Count; Cells, Cultured; Cobalt; Dose-Response Relationship, Drug; Kainic Acid; Mice; Mice, Inbred Strains; N-Methylaspartate; Nerve Degeneration; Receptors, AMPA; Receptors, Kainic Acid	1995
Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator. Nature, 1995, Sep-28, Volume: 377, Issue:6547 Topics: Animals; Drug Resistance; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Nerve Degeneration; Seizures; Tissue Plasminogen Activator	1995
Staurosporine-induced neuronal apoptosis. Experimental neurology, 1995, Volume: 135, Issue:2 Topics: Alkaloids; Animals; Apoptosis; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Kainic Acid; Mice; Mice, Inbred Strains; N-Methylaspartate; Nerve Degeneration; Neurons; Staurosporine; Time Factors	1995
Elevated cathepsin D expression in kainate-evoked rat brain neurodegeneration. Experimental neurology, 1995, Volume: 136, Issue:1 Topics: Animals; Blotting, Northern; Brain; Cathepsin D; Cerebral Cortex; Glial Fibrillary Acidic Protein; Immunohistochemistry; Kainic Acid; Male; Nerve Degeneration; Rats; Rats, Wistar; RNA, Messenger; Seizures; Time Factors	1995
The cardiac glycoside ouabain potentiates excitotoxic injury of adult neurons in rat hippocampus. Neuroscience letters, 1995, May-26, Volume: 191, Issue:3 Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Electroencephalography; Hippocampus; Kainic Acid; Limbic System; Nerve Degeneration; Neurons; Ouabain; Rats; Seizures; Sodium-Potassium-Exchanging ATPase	1995
Delayed cell death in the contralateral hippocampus following kainate injection into the CA3 subfield. Neuroscience, 1995, Volume: 66, Issue:4 Topics: Animals; Calbindin 2; Cell Death; Disease Models, Animal; Epilepsy, Temporal Lobe; Functional Laterality; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Nerve Degeneration; Pyramidal Cells; Rats; Rats, Wistar; S100 Calcium Binding Protein G; Silver Staining; Time Factors	1995
A comparative analysis of the neuroprotective properties of competitive and uncompetitive N-methyl-D-aspartate receptor antagonists in vivo: implications for the process of excitotoxic degeneration and its therapy. Neuroscience, 1993, Volume: 55, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Biomarkers; Cell Death; Choline O-Acetyltransferase; Corpus Striatum; Dizocilpine Maleate; Drug Administration Schedule; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Injections; Injections, Intraperitoneal; Kainic Acid; Male; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neurotoxins; Pipecolic Acids; Piperazines; Quinolinic Acid; Rats; Receptors, N-Methyl-D-Aspartate	1993
Propidium iodide in vivo: an early marker of neuronal damage in rat hippocampus. Neuroscience letters, 1994, Oct-24, Volume: 180, Issue:2 Topics: Animals; Biological Transport; Cell Death; Chromatin; Fluorescent Dyes; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Nerve Degeneration; Propidium; Pyramidal Cells; Rats; Rats, Wistar	1994
Accumulation of extracellular glutamate by inhibition of its uptake is not sufficient for inducing neuronal damage: an in vivo microdialysis study. Journal of neurochemistry, 1995, Volume: 64, Issue:5 Topics: Animals; Cell Death; Choline; Choline O-Acetyltransferase; Corpus Striatum; Dicarboxylic Acids; Dizocilpine Maleate; Extracellular Space; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Kainic Acid; Male; Microdialysis; Nerve Degeneration; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar	1995
Periodic acid-Schiff (PAS)-positive deposits in brain following kainic acid-induced seizures: relationships to fos induction, neuronal necrosis, reactive gliosis, and blood-brain barrier breakdown. Acta neuropathologica, 1995, Volume: 89, Issue:2 Topics: Animals; Blood-Brain Barrier; Brain; Brain Mapping; Epilepsy; Extracellular Matrix; Gliosis; Immunohistochemistry; Kainic Acid; Male; Necrosis; Nerve Degeneration; Periodic Acid-Schiff Reaction; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Status Epilepticus	1995
Non-NMDA receptors in motor neuron disease (MND): a quantitative autoradiographic study in spinal cord and motor cortex using [3H]CNQX and [3H]kainate. Brain research, 1994, Aug-29, Volume: 655, Issue:1-2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; Aged; Autoradiography; Female; Humans; Kainic Acid; Male; Middle Aged; Motor Cortex; Motor Neuron Disease; Nerve Degeneration; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Spinal Cord	1994
Neuron damage induced by some potent kainoids and neuroprotective action of new agonists for metabotropic glutamate receptors. European neurology, 1994, Volume: 34 Suppl 3 Topics: Amino Acids, Dicarboxylic; Animals; Animals, Newborn; Brain; Culture Techniques; Cyclopropanes; Dose-Response Relationship, Drug; Ganglia, Spinal; Glycine; Kainic Acid; Motor Neurons; Nerve Degeneration; Neuromuscular Diseases; Neurons; Rats; Receptors, Metabotropic Glutamate; Spinal Cord; Stereoisomerism; Structure-Activity Relationship; Synaptic Transmission	1994
Decreased excitotoxic sensitivity in the olfactory cortex of adult rats after neonatal NMDA blockade. Neuroreport, 1994, Oct-27, Volume: 5, Issue:16 Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Animals, Newborn; Enzyme Induction; Hippocampus; Kainic Acid; Nerve Degeneration; Olfactory Bulb; Ornithine Decarboxylase; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	1994
Proliferative astrocytes may express fibronectin-like protein in the hippocampus of epileptic rats. Neuroscience letters, 1994, Oct-10, Volume: 180, Issue:1 Topics: Animals; Astrocytes; Cell Division; Epilepsy; Fibronectins; Glial Fibrillary Acidic Protein; Hippocampus; Histocytochemistry; Kainic Acid; Male; Nerve Degeneration; Rats; Rats, Wistar; Thymidine	1994
Comparison of double fluorescence staining and LDH-test for monitoring cell viability in vitro. Neuroreport, 1993, Nov-18, Volume: 5, Issue:2 Topics: Animals; Biomarkers; Cell Survival; Cells, Cultured; Cerebral Cortex; Culture Media, Conditioned; Cytological Techniques; Fluoresceins; Fluorescent Dyes; Glutamates; Glutamic Acid; Hydrolysis; Kainic Acid; L-Lactate Dehydrogenase; Microscopy, Fluorescence; N-Methylaspartate; Nerve Degeneration; Nerve Tissue Proteins; Neuroglia; Neurons; Neurotoxins; Propidium; Quinolinic Acid; Rats; Rats, Wistar	1993
Blockade by 1,3-dipropyl-8-cyclopentylxanthine (CPX) of purine protection against kainate neurotoxicity. Brain research, 1994, May-02, Volume: 644, Issue:2 Topics: Animals; Kainic Acid; Male; Nerve Degeneration; Phenylisopropyladenosine; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Xanthines	1994
Neuroexcitatory and neurotoxic actions of the amnesic shellfish poison, domoic acid. Neuroreport, 1994, Apr-14, Volume: 5, Issue:8 Topics: Animals; Blotting, Northern; Brain; Brain Chemistry; Brain Stem; Female; Immunohistochemistry; Kainic Acid; Mice; Mice, Inbred ICR; Nerve Degeneration; Neurons; Neurotoxins; Proto-Oncogene Proteins c-fos; Silver Staining	1994
Glutamate neurotoxicity: a role for non-N-methyl-D-aspartate receptors? Biochemical Society transactions, 1993, Volume: 21, Issue:1 Topics: Animals; Brain; Cells, Cultured; Choline O-Acetyltransferase; Glutamates; Glutamic Acid; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Somatostatin	1993
Early response of brain resident microglia to kainic acid-induced hippocampal lesions. Brain research, 1994, Jan-28, Volume: 635, Issue:1-2 Topics: Animals; Brain; Cell Adhesion Molecules; Complement System Proteins; Hippocampus; Immunohistochemistry; Injections, Intraventricular; Kainic Acid; Lymphocyte Function-Associated Antigen-1; Male; Microglia; Models, Neurological; Nerve Degeneration; Nerve Tissue Proteins; Rats; Rats, Wistar	1994
Selective neuronal death in the contralateral hippocampus following unilateral kainate injections into the CA3 subfield. Neuroscience, 1993, Volume: 56, Issue:2 Topics: Anesthetics; Animals; Biomarkers; Calbindin 2; Cell Death; Chloral Hydrate; Disease Models, Animal; Dominance, Cerebral; Dose-Response Relationship, Drug; Drug Combinations; Epilepsy, Temporal Lobe; Ether; Hippocampus; Injections; Injections, Intraperitoneal; Kainic Acid; Magnesium Sulfate; Male; Necrosis; Nerve Degeneration; Nerve Tissue Proteins; Neural Pathways; Neurons; Pentobarbital; Pyramidal Cells; Rats; Rats, Wistar; S100 Calcium Binding Protein G; Seizures	1993
Selective excitotoxic pathology in the rat hippocampus. Neuropathology and applied neurobiology, 1993, Volume: 19, Issue:5 Topics: Animals; Brain; Brain Damage, Chronic; Cell Death; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Organ Specificity; Piperazines; Quisqualic Acid; Rats; Rats, Sprague-Dawley	1993
Co-expression of HSP72 and c-fos in rat brain following kainic acid treatment. Neuroreport, 1993, Dec-13, Volume: 5, Issue:3 Topics: Animals; Brain Chemistry; Gene Expression; Genes, fos; Heat-Shock Proteins; Immunohistochemistry; In Situ Hybridization; Kainic Acid; Male; Nerve Degeneration; Rats; Rats, Sprague-Dawley; RNA Probes; RNA, Messenger	1993
Domoic acid-treated cynomolgus monkeys (M. fascicularis): effects of dose on hippocampal neuronal and terminal degeneration. Brain research, 1993, Nov-12, Volume: 627, Issue:2 Topics: Animals; Dose-Response Relationship, Drug; Female; Hippocampus; Kainic Acid; Macaca fascicularis; Male; Marine Toxins; Nerve Degeneration; Nerve Endings; Neurons; Neurotoxins; Silver Staining	1993
Increased levels of the Kunitz protease inhibitor-containing beta APP mRNAs in rat brain following neurotoxic damage. Brain research. Molecular brain research, 1993, Volume: 17, Issue:1-2 Topics: Amyloid beta-Protein Precursor; Animals; Astrocytes; Base Sequence; Brain; Enzyme Induction; Glial Fibrillary Acidic Protein; Hippocampus; Isoenzymes; Kainic Acid; Male; Molecular Sequence Data; Nerve Degeneration; Nerve Tissue Proteins; Rats; Rats, Wistar; RNA, Messenger; Serine Proteinase Inhibitors	1993
Microglial MHC antigen expression after ischemic and kainic acid lesions of the adult rat hippocampus. Glia, 1993, Volume: 7, Issue:1 Topics: Animals; Brain Diseases; Brain Ischemia; Hippocampus; Histocompatibility Antigens; Kainic Acid; Leukocyte Common Antigens; Male; Nerve Degeneration; Neuroglia; Rats; Rats, Wistar	1993
A benzodiazepine recognition site associated with the non-NMDA glutamate receptor. Neuron, 1993, Volume: 10, Issue:1 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Binding Sites; Binding, Competitive; Cells, Cultured; Chick Embryo; Electric Conductivity; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Nerve Degeneration; Neurons; Quisqualic Acid; Rats; Receptors, Glutamate; Retina	1993
The use of sodium sulphide-fixed brain tissue for immunocytochemical staining of activated microglia and reactive astrocytes. Histochemistry, 1993, Volume: 99, Issue:1 Topics: Animals; Antibodies, Monoclonal; Astrocytes; Benzoxazines; Fluorescein-5-isothiocyanate; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Injections, Intraventricular; Kainic Acid; Male; Nerve Degeneration; Neuroglia; Oxazines; Rats; Rats, Wistar; Sulfides; Tissue Fixation	1993
Degeneration of rat thalamic reticular neurons following intrathalamic domoic acid injection. Neuroscience letters, 1993, Mar-05, Volume: 151, Issue:1 Topics: Animals; Dopamine; In Vitro Techniques; Injections; Kainic Acid; Male; Motor Activity; Nerve Degeneration; Neuromuscular Depolarizing Agents; Rats; Reticular Formation; Thalamic Nuclei; Thalamus	1993
Continuous c-fos expression precedes programmed cell death in vivo. Nature, 1993, May-13, Volume: 363, Issue:6425 Topics: 3T3 Cells; Animals; beta-Galactosidase; Cell Death; Cells, Cultured; Central Nervous System; Etoposide; Female; Kainic Acid; Male; Mice; Mice, Mutant Strains; Mice, Transgenic; Nerve Degeneration; Neurons; Ovary; Proto-Oncogene Proteins c-fos; Tooth	1993
Regressive modifications of climbing fibres following Purkinje cell degeneration in the cerebellar cortex of the adult rat. Neuroscience, 1993, Volume: 53, Issue:3 Topics: Animals; Cerebellar Cortex; Immunohistochemistry; Kainic Acid; Nerve Degeneration; Nerve Fibers; Olivary Nucleus; Phytohemagglutinins; Propidium; Purkinje Cells; Rats; Rats, Wistar	1993
TGF-beta 1 mRNA increases in macrophage/microglial cells of the hippocampus in response to deafferentation and kainic acid-induced neurodegeneration. Experimental neurology, 1993, Volume: 120, Issue:2 Topics: Afferent Pathways; Animals; Glial Fibrillary Acidic Protein; Hippocampus; Kainic Acid; Limbic System; Macrophages; Male; Mesoderm; Nerve Degeneration; Rats; Rats, Inbred F344; RNA, Messenger; Seizures; Temporal Lobe; Transforming Growth Factor beta	1993
Glucocorticoids depress activity-dependent expression of BDNF mRNA in hippocampal neurones. Neuroreport, 1993, Volume: 4, Issue:5 Topics: Animals; Brain-Derived Neurotrophic Factor; Depression, Chemical; Dexamethasone; Female; Glucocorticoids; Hippocampus; In Situ Hybridization; Kainic Acid; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Potassium; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation	1993
Kainic acid decreases hippocampal neuronal number and increases dopamine receptor binding in the nucleus accumbens: an animal model of schizophrenia. Behavioural brain research, 1995, Volume: 70, Issue:2 Topics: Animals; Brain Mapping; Caudate Nucleus; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Motor Activity; Nerve Degeneration; Neural Pathways; Nucleus Accumbens; Putamen; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Schizophrenia; Spiperone; Temporal Lobe; Up-Regulation	1995
Domoic acid-induced neuronal degeneration in the primate forebrain revealed by degeneration specific histochemistry. Brain research, 1995, Oct-09, Volume: 695, Issue:1 Topics: Animals; Entorhinal Cortex; Female; Hippocampus; Kainic Acid; Macaca mulatta; Male; Nerve Degeneration; Neuromuscular Depolarizing Agents; Prosencephalon; Pyramidal Cells	1995
Alpha 2-adrenoceptor agonist, dexmedetomidine, protects against kainic acid-induced convulsions and neuronal damage. Brain research, 1995, Sep-25, Volume: 693, Issue:1-2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Anticonvulsants; Disease Models, Animal; gamma-Aminobutyric Acid; Hippocampus; Histocytochemistry; Imidazoles; Kainic Acid; Male; Medetomidine; Nerve Degeneration; Neurons; Rats; Rats, Wistar; Seizures; Status Epilepticus; Vigabatrin	1995
Occurrence of lamellar bodies in the rat brain organotypic cultures in normal and pathological conditions. Folia neuropathologica, 1995, Volume: 33, Issue:3 Topics: Animals; Astrocytes; Brain; Hypoxia; In Vitro Techniques; Kainic Acid; Nerve Degeneration; Organelles; Quinolinic Acid; Rats; Rats, Wistar	1995
Developmental and plasticity-related differential expression of two SNAP-25 isoforms in the rat brain. The Journal of comparative neurology, 1996, Apr-01, Volume: 367, Issue:2 Topics: Animals; Base Sequence; Brain; Embryonic and Fetal Development; Gene Expression Regulation, Developmental; Kainic Acid; Membrane Proteins; Molecular Sequence Data; Nerve Degeneration; Nerve Tissue Proteins; Neuronal Plasticity; Oligonucleotide Probes; Rats; Rats, Wistar; Synaptosomal-Associated Protein 25	1996
Induction of NF-kB-like transcription factors in brain areas susceptible to kainate toxicity. Glia, 1996, Volume: 16, Issue:4 Topics: Animals; Base Sequence; Biotransformation; Brain; Brain Chemistry; Cytoplasm; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Gliosis; Hippocampus; Immunohistochemistry; Kainic Acid; Macrophage Activation; Male; Microglia; Molecular Sequence Data; Nerve Degeneration; NF-kappa B; Oligonucleotide Probes; Rats; Rats, Inbred F344	1996
Zn(2+) permeates Ca(2+) permeable AMPA/kainate channels and triggers selective neural injury. Neuroreport, 1995, Dec-15, Volume: 6, Issue:18 Topics: Animals; Cell Count; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Kainic Acid; Mice; Nerve Degeneration; Receptors, AMPA; Receptors, Kainic Acid; Zinc	1995
Ca(2+)-permeable AMPA/kainate and NMDA channels: high rate of Ca2+ influx underlies potent induction of injury. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Sep-01, Volume: 16, Issue:17 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Intracellular Membranes; Kainic Acid; Mice; Mice, Inbred Strains; N-Methylaspartate; Nerve Degeneration; Osmolar Concentration; Permeability; Time Factors	1996
Subthalamic nucleus lesion in rats prevents dopaminergic nigral neuron degeneration after striatal 6-OHDA injection: behavioural and immunohistochemical studies. The European journal of neuroscience, 1996, Volume: 8, Issue:7 Topics: Animals; Dopamine; Drug Administration Schedule; Functional Laterality; Immunohistochemistry; Kainic Acid; Male; Motor Activity; Nerve Degeneration; Oxidopamine; Rats; Rats, Wistar; Rotation; Substantia Nigra; Thalamic Nuclei	1996
Kainic acid versus carbachol induced emotional-defensive response in the cat. Behavioural brain research, 1996, Volume: 77, Issue:1-2 Topics: Agonistic Behavior; Animals; Arousal; Brain Mapping; Carbachol; Cats; Dose-Response Relationship, Drug; Electroencephalography; Emotions; Female; Hypothalamus, Anterior; Hypothalamus, Middle; Kainic Acid; Kindling, Neurologic; Limbic System; Male; Nerve Degeneration; Neural Pathways; Neuroglia; Neurons; Periaqueductal Gray	1996
Inhibition of glutamate uptake induces progressive accumulation of extracellular glutamate and neuronal damage in rat cortical cultures. Journal of neuroscience research, 1996, Jun-15, Volume: 44, Issue:6 Topics: Animals; Anti-Bacterial Agents; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Kainic Acid; L-Lactate Dehydrogenase; Nerve Degeneration; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	1996
Prevention by a purine analogue of kainate-induced neuropathology in rat hippocampus. Brain research, 1996, Jun-24, Volume: 725, Issue:1 Topics: Animals; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Neuroprotective Agents; Phenylisopropyladenosine; Rats; Rats, Wistar	1996
Expression of non-angiotensin II -125I-CGP 42112 binding sites on activated microglia after kainic acid induced neurodegeneration. Brain research, 1995, Dec-08, Volume: 702, Issue:1-2 Topics: Angiotensin II; Animals; Autoradiography; Binding Sites; Dose-Response Relationship, Drug; Hippocampus; Kainic Acid; Male; Microglia; Nerve Degeneration; Oligopeptides; Rats; Rats, Sprague-Dawley; Time Factors	1995
Selective degeneration of inhibitory interneurons in the rat spinal cord induced by intrathecal infusion of acromelic acid. Brain research, 1995, Dec-08, Volume: 702, Issue:1-2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dose-Response Relationship, Drug; Injections, Spinal; Interneurons; Kainic Acid; Male; Nerve Degeneration; Rats; Rats, Wistar; Spinal Cord; Time Factors	1995
Entactin immunoreactivity in immature and adult rat brain. Brain research. Developmental brain research, 1996, Sep-02, Volume: 95, Issue:2 Topics: Animals; Antibody Specificity; Basement Membrane; Hippocampus; Immunohistochemistry; Kainic Acid; Laminin; Male; Membrane Glycoproteins; Neoplasm Proteins; Nerve Degeneration; Nerve Regeneration; Nerve Tissue Proteins; Rats; Rats, Wistar; Staining and Labeling	1996
Local injection of kainic acid causes widespread degeneration of NADPH-d neurons and induction of NADPH-d in neurons, endothelial cells and reactive astrocytes. Brain research, 1996, Aug-19, Volume: 730, Issue:1-2 Topics: Animals; Astrocytes; Cerebral Cortex; Cerebrovascular Circulation; Endothelium, Vascular; Enzyme Induction; Histocytochemistry; Injections; Kainic Acid; Male; NADPH Dehydrogenase; Nerve Degeneration; Neurons; Rats; Rats, Wistar; Time Factors	1996
Kainate induces apoptosis in neurons. Neuroscience, 1996, Volume: 74, Issue:3 Topics: Animals; Anisomycin; Apoptosis; Aurintricarboxylic Acid; Cell Nucleus; Cerebellum; Cycloheximide; Dactinomycin; DNA; Electrophoresis, Agar Gel; Kainic Acid; Kinetics; Nerve Degeneration; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley	1996
Studies of NMDA- and non-NMDA-mediated neurotoxicity in cultured neurons. Neurochemistry international, 1996, Volume: 29, Issue:3 Topics: Animals; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Kainic Acid; Nerve Degeneration; Neurons; Quinoxalines; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate	1996
Delayed neuronal death in ischemic hippocampus involves stimulation of protein tyrosine phosphorylation. The American journal of physiology, 1996, Volume: 271, Issue:4 Pt 1 Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Death; Enzyme Inhibitors; Gerbillinae; Hippocampus; Ischemia; Kainic Acid; Lactones; Macrolides; Male; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Phosphoproteins; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Reperfusion Injury; Time Factors	1996
Neuronal cell death and tPA. Nature, 1996, Nov-14, Volume: 384, Issue:6605 Topics: Animals; Cell Death; Hippocampus; Kainic Acid; Mice; Nerve Degeneration; Neurons; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Serine Proteinase Inhibitors; Tissue Plasminogen Activator	1996
Effect of spinal kainic acid receptor activation on spinal amino acid and prostaglandin E2 release in rat. Neuroscience, 1996, Volume: 75, Issue:2 Topics: Animals; Dinoprostone; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acids; Extracellular Space; Injections, Spinal; Kainic Acid; Male; Nerve Degeneration; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Spinal Cord	1996
Absence of excitotoxic neuropathology in microencephalic rats after systemic kainic acid administration. Neuroscience letters, 1996, Oct-25, Volume: 218, Issue:1 Topics: Animals; Cell Death; Female; Glutamic Acid; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Olfactory Pathways; Pregnancy; Rats; Rats, Wistar	1996
Hereditary deficiencies in complement C5 are associated with intensified neurodegenerative responses that implicate new roles for the C-system in neuronal and astrocytic functions. Neurobiology of disease, 1996, Volume: 3, Issue:3 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Cell Death; Cells, Cultured; Complement C5; Electrophysiology; Hippocampus; Interleukin-6; Kainic Acid; Lipopolysaccharides; Mice; Mice, Inbred Strains; Nerve Degeneration; Pyramidal Cells; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tumor Necrosis Factor-alpha	1996
An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Jan-15, Volume: 17, Issue:2 Topics: alpha-2-Antiplasmin; Animals; DNA, Complementary; Drug Resistance; Endopeptidases; Excitatory Amino Acid Agonists; Extracellular Space; Fibrinolysin; Hippocampus; Kainic Acid; Male; Mice; Mice, Knockout; Microglia; Models, Neurological; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Organ Specificity; Plasminogen; RNA, Messenger; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator	1997
Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration. Brain research, 1997, Mar-14, Volume: 751, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antihypertensive Agents; Axons; Dizocilpine Maleate; Dopamine Agents; Eosine Yellowish-(YS); Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Eye Enucleation; Fluorescent Antibody Technique; Fluorescent Dyes; Hallucinogens; Hematoxylin; Ibogaine; Kainic Acid; Male; Metals; Nerve Degeneration; Nissl Bodies; Nitro Compounds; Phencyclidine; Propionates; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Silver Staining; Stereotaxic Techniques	1997
Non-NMDA and NMDA receptor-mediated excitotoxic neuronal deaths in adult brain are morphologically distinct: further evidence for an apoptosis-necrosis continuum. The Journal of comparative neurology, 1997, Feb-03, Volume: 378, Issue:1 Topics: Animals; Apoptosis; Brain; Cell Death; Dizocilpine Maleate; Kainic Acid; Male; Necrosis; Nerve Degeneration; Neurons; Neurotoxins; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate	1997
Amyloid precursor proteins protect neurons of transgenic mice against acute and chronic excitotoxic injuries in vivo. Neuroscience, 1997, Volume: 78, Issue:1 Topics: Amyloid beta-Protein Precursor; Animals; Brain; Excitatory Amino Acid Agonists; Gene Expression; Gliosis; HIV Envelope Protein gp120; Humans; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Degeneration; Neurons; Neurotoxins; RNA, Messenger; Transgenes	1997
Seizure-induced alterations of plasma membrane calcium ATPase isoforms 1, 2 and 3 mRNA and protein in rat hippocampus. Brain research. Molecular brain research, 1997, Volume: 45, Issue:2 Topics: Animals; Calcium-Transporting ATPases; Cell Membrane; Hippocampus; Isoenzymes; Kainic Acid; Male; Nerve Degeneration; Prosencephalon; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; RNA, Messenger; Seizures; Transcription, Genetic	1997
Network properties of the dentate gyrus in epileptic rats with hilar neuron loss and granule cell axon reorganization. Journal of neurophysiology, 1997, Volume: 77, Issue:5 Topics: Animals; Axons; Brain Mapping; Dentate Gyrus; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Evoked Potentials; Kainic Acid; Male; Nerve Degeneration; Nerve Net; Nerve Regeneration; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Receptors, GABA-A	1997
Maturational regulation and regional induction of cyclooxygenase-2 in rat brain: implications for Alzheimer's disease. Experimental neurology, 1997, Volume: 144, Issue:2 Topics: Alzheimer Disease; Amygdala; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Brain; Cells, Cultured; Cerebral Cortex; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Induction; Excitatory Amino Acid Agonists; Gene Expression Regulation, Developmental; Hippocampus; Isoenzymes; Kainic Acid; Nerve Degeneration; Nerve Tissue Proteins; Organ Specificity; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Seizures	1997
Glutamate uptake impairment and neuronal damage in young and aged rats in vivo. Journal of neurochemistry, 1997, Volume: 69, Issue:3 Topics: Aging; Amino Acids; Animals; Aspartic Acid; Corpus Striatum; Dicarboxylic Acids; Glutamic Acid; Hippocampus; Kainic Acid; Kinetics; Male; Microdialysis; Nerve Degeneration; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar	1997
GABA(A) receptor subunits in the rat hippocampus II: altered distribution in kainic acid-induced temporal lobe epilepsy. Neuroscience, 1997, Volume: 80, Issue:4 Topics: Animals; Dentate Gyrus; Epilepsy, Temporal Lobe; Hippocampus; Humans; Immunohistochemistry; Interneurons; Kainic Acid; Macromolecular Substances; Male; Nerve Degeneration; Neurons; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Time Factors	1997
Systemic administration of kainic acid induces selective time dependent decrease in [125I]insulin-like growth factor I, [125I]insulin-like growth factor II and [125I]insulin receptor binding sites in adult rat hippocampal formation. Neuroscience, 1997, Volume: 80, Issue:4 Topics: Animals; Autoradiography; Binding Sites; Cell Survival; Dentate Gyrus; Down-Regulation; Epilepsy, Temporal Lobe; Hippocampus; Humans; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Iodine Radioisotopes; Kainic Acid; Male; Nerve Degeneration; Neurons; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Receptor, IGF Type 2; Receptor, Insulin; Time Factors	1997
Expression of activating transcription factor-2, serum response factor and cAMP/Ca response element binding protein in the adult rat brain following generalized seizures, nerve fibre lesion and ultraviolet irradiation. Neuroscience, 1997, Volume: 81, Issue:1 Topics: Activating Transcription Factor 2; Age Factors; Animals; Antibody Specificity; Axotomy; Brain Chemistry; Cyclic AMP Response Element-Binding Protein; DNA-Binding Proteins; Epilepsy, Generalized; Excitatory Amino Acid Agonists; Kainic Acid; Leucine Zippers; Male; Nerve Degeneration; Nerve Fibers; Nuclear Proteins; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Serum Response Factor; Synaptic Transmission; Transcription Factors; Ultraviolet Rays	1997
Astrocytes may contribute to the latent period in progressive neuron loss, axon sprouting, and chronic seizures in rat kainate hippocampal epilepsy. Epilepsy research. Supplement, 1996, Volume: 12 Topics: Animals; Astrocytes; Axons; Cell Count; Epilepsy; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Nerve Regeneration; Rats; Rats, Sprague-Dawley	1996
Status epilepticus-induced alterations in metabotropic glutamate receptor expression in young and adult rats. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Nov-01, Volume: 17, Issue:21 Topics: Aging; Animals; Animals, Suckling; Cell Death; Dentate Gyrus; Excitatory Amino Acid Agonists; Gene Expression Regulation, Developmental; Glutamic Acid; In Situ Hybridization, Fluorescence; Kainic Acid; Male; Mossy Fibers, Hippocampal; Nerve Degeneration; Nerve Tissue Proteins; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; RNA, Messenger; Status Epilepticus	1997
Neurotoxic responses by microglia elicited by excitotoxic injury in the mouse hippocampus. Current biology : CB, 1998, Jan-01, Volume: 8, Issue:1 Topics: Animals; Cell Death; Cells, Cultured; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Hippocampus; Kainic Acid; Macrophage Migration-Inhibitory Factors; Male; Mice; Mice, Inbred C57BL; Microglia; Nerve Degeneration; Neurons; Pregnancy; Tissue Plasminogen Activator	1998
Kainate-stimulated Zn2+ uptake labels cortical neurons with Ca2+-permeable AMPA/kainate channels. Brain research, 1998, Jan-19, Volume: 781, Issue:1-2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Chemical Precipitation; Cobalt; Ion Channels; Kainic Acid; Membrane Potentials; Mice; Nerve Degeneration; Neurons; Permeability; Zinc	1998
Regionally specific induction of BDNF and truncated trkB.T1 receptors in the hippocampal formation after intraseptal injection of kainic acid. Brain research, 1998, Apr-20, Volume: 790, Issue:1-2 Topics: Animals; Brain-Derived Neurotrophic Factor; Choline O-Acetyltransferase; Excitatory Amino Acid Agonists; Female; gamma-Aminobutyric Acid; Gene Expression Regulation, Enzymologic; Glutamate Decarboxylase; Hippocampus; Kainic Acid; Microinjections; Nerve Degeneration; Prosencephalon; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Receptor, Ciliary Neurotrophic Factor; Receptor, trkA; Receptors, Nerve Growth Factor; RNA, Messenger; Septal Nuclei	1998
Degeneration of the dendritic arbor as an index of neurotoxicity in identified catecholamine neurons in rat brain slices. Experimental neurology, 1998, Volume: 151, Issue:2 Topics: Animals; Catecholamines; Dendrites; Excitatory Amino Acid Agonists; Kainic Acid; Male; Microtomy; Nerve Degeneration; Neurotoxins; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase	1998
Excitatory amino acid-induced degeneration of dendrites of catecholamine neurons in rat substantia nigra. Experimental neurology, 1998, Volume: 151, Issue:2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Catecholamines; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Substantia Nigra	1998
Intrinsic optical signaling denoting neuronal damage in response to acute excitotoxic insult by domoic acid in the hippocampal slice. Neurobiology of disease, 1998, Volume: 4, Issue:6 Topics: Animals; Calcium Chloride; Dendrites; Electrophysiology; Fluorescent Dyes; Hippocampus; Image Cytometry; Image Processing, Computer-Assisted; Isoquinolines; Kainic Acid; Male; Membrane Potentials; Microinjections; Nerve Degeneration; Neuromuscular Depolarizing Agents; Neurons; Neurotoxins; Optics and Photonics; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA	1998
Induction of plasminogen in rat hippocampal pyramidal neurons by kainic acid. Neuroscience letters, 1998, Aug-14, Volume: 252, Issue:2 Topics: Animals; Antibodies; Excitatory Amino Acid Agonists; Extracellular Matrix; Fibrinolysin; Gene Expression; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Plasminogen; Plasminogen Activators; Pyramidal Cells; Rats; Rats, Wistar; RNA, Messenger	1998
Selective reduction of GluR2 protein in adult hippocampal CA3 neurons following status epilepticus but prior to cell loss. Hippocampus, 1998, Volume: 8, Issue:5 Topics: Animals; Cell Count; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Microscopy, Electron; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reference Values; RNA, Messenger; Silver Staining; Status Epilepticus	1998
Progressive neurodegeneration after intracerebroventricular kainic acid administration in rats: implications for schizophrenia? Biological psychiatry, 1998, Dec-01, Volume: 44, Issue:11 Topics: Animals; Cerebral Ventricles; Cognition Disorders; Hippocampus; Kainic Acid; Limbic System; Male; Nerve Degeneration; Rats; Schizophrenia; Time Factors	1998
The effect of acute kainic acid treatment on mu-opioid receptors in rat brain. Brain research, 1998, Dec-14, Volume: 814, Issue:1-2 Topics: Animals; Brain; Kainic Acid; Linear Models; Male; Nerve Degeneration; Neurotoxins; Radioligand Assay; Rats; Rats, Wistar; Receptors, Opioid, mu	1998
Heparin-binding epidermal growth factor-like growth factor in hippocampus: modulation of expression by seizures and anti-excitotoxic action. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Jan-01, Volume: 19, Issue:1 Topics: Animals; Epidermal Growth Factor; Female; Heparin; Heparin-binding EGF-like Growth Factor; Hippocampus; Intercellular Signaling Peptides and Proteins; Kainic Acid; Male; Nerve Degeneration; Neuroprotective Agents; Prosencephalon; Rats; Rats, Sprague-Dawley; RNA, Messenger; Seizures	1999
Differential blood-brain barrier breakdown and leucocyte recruitment following excitotoxic lesions in juvenile and adult rats. Experimental neurology, 1998, Volume: 154, Issue:1 Topics: Aging; Animals; Astrocytes; Biomarkers; Blood-Brain Barrier; Brain; Excitatory Amino Acid Agonists; Immunoenzyme Techniques; Inflammation; Kainic Acid; Leukocytes; Male; Microglia; N-Methylaspartate; Nerve Degeneration; Permeability; Rats; Rats, Wistar; Time Factors	1998
Status epilepticus induces p53 sequence-specific DNA binding in mature rat brain. Brain research. Molecular brain research, 1999, Jan-08, Volume: 63, Issue:2 Topics: Animals; Brain; Cycloheximide; Gene Expression Regulation; Genes, p53; Kainic Acid; Male; Nerve Degeneration; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Status Epilepticus; Tumor Suppressor Protein p53	1999
Kainic acid-induced activation of nuclear factor-kappaB in rat hippocampus. Experimental brain research, 1999, Volume: 124, Issue:2 Topics: Animals; Astrocytes; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Hippocampus; Injections, Intraventricular; Kainic Acid; Macrophage-1 Antigen; Male; Microglia; Nerve Degeneration; Neuroimmunomodulation; NF-kappa B; Rats; Rats, Wistar	1999
The antioxidant melatonin reduces cortical neuronal death after intrastriatal injection of kainate in the rat. Experimental brain research, 1999, Volume: 124, Issue:2 Topics: Animals; Antioxidants; Apoptosis; Cerebral Cortex; Corpus Striatum; Excitatory Amino Acid Agonists; Glutathione; Glutathione Peroxidase; In Situ Nick-End Labeling; Kainic Acid; Male; Melatonin; Nerve Degeneration; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley	1999
Markers for neuronal degeneration in organotypic slice cultures. Brain research. Brain research protocols, 1999, Volume: 3, Issue:3 Topics: Animals; Animals, Newborn; Biomarkers; Calcium Channels; Cells, Cultured; Cerebral Cortex; Cobalt; Coloring Agents; Corpus Striatum; Excitatory Amino Acid Agonists; Fluorescent Dyes; Hippocampus; Image Processing, Computer-Assisted; Ion Transport; Kainic Acid; Microtubule-Associated Proteins; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Propidium; Rats; Rats, Wistar; Silver Staining; Tolonium Chloride	1999
Increased cyclin D1 in vulnerable neurons in the hippocampus after ischaemia and epilepsy: a modulator of in vivo programmed cell death? The European journal of neuroscience, 1999, Volume: 11, Issue:1 Topics: Amygdala; Animals; Apoptosis; Biomarkers; Brain Ischemia; Cell Cycle; Cell Nucleus; Cyclin D1; Cyclin D2; Cyclin D3; Cyclins; Epilepsy; Excitatory Amino Acid Agonists; Gene Expression; Hippocampus; In Situ Hybridization; Kainic Acid; Male; Nerve Degeneration; Neurons; Neurotoxins; Prosencephalon; Rats; Rats, Wistar; RNA, Messenger; Time Factors	1999
Zn2+ entry produces oxidative neuronal necrosis in cortical cell cultures. The European journal of neuroscience, 1999, Volume: 11, Issue:1 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Chloromethyl Ketones; Animals; Antioxidants; Apoptosis; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Chromans; Cysteine Proteinase Inhibitors; Dizocilpine Maleate; Dopamine Agonists; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Free Radicals; Hypoglycemic Agents; Insulin; Kainic Acid; Lipid Peroxidation; Mice; Microscopy, Electron; Mitochondrial Swelling; Necrosis; Nerve Degeneration; Neurons; Neurotoxins; Oligopeptides; Oxidative Stress; Pregnancy; Zinc	1999
Motor neuron degeneration is attenuated in bax-deficient neurons in vitro. Journal of neuroscience research, 1999, Mar-01, Volume: 55, Issue:5 Topics: Animals; Aspartic Acid; Astrocytes; bcl-2-Associated X Protein; Cell Death; Cell Division; Cell Nucleus; Cell Size; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Female; Genotype; Kainic Acid; Male; Mice; Motor Neurons; Nerve Degeneration; Paraquat; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Spinal Cord; Superoxides	1999
A nuclear microscopic study of elemental changes in the rat hippocampus after kainate-induced neuronal injury. Journal of neurochemistry, 1999, Volume: 72, Issue:4 Topics: Animals; Astrocytes; Calcium; Excitatory Amino Acid Agonists; Hippocampus; Injections, Intraventricular; Kainic Acid; Macrophages; Male; Microscopy, Electron, Scanning Transmission; Nerve Degeneration; Neurotoxins; Nissl Bodies; Pyramidal Cells; Rats; Rats, Wistar; Spectrometry, X-Ray Emission	1999
Neuronal degeneration and a decrease in laminin-like immunoreactivity is associated with elevated tissue-type plasminogen activator in the rat hippocampus after kainic acid injection. Neuroscience research, 1999, Volume: 33, Issue:2 Topics: Animals; Cerebral Ventricles; Hippocampus; Kainic Acid; Kinetics; Laminin; Male; Nerve Degeneration; Neurons; Rats; Rats, Wistar; Time Factors; Tissue Plasminogen Activator	1999
Trimetazidine prevents cochlear lesions induced by intraperitoneal and perilymphatic administration of kainic acid. Brain research, 1999, Apr-24, Volume: 826, Issue:1 Topics: Animals; Electrophysiology; Excitatory Amino Acid Agonists; Injections, Intralymphatic; Injections, Intraperitoneal; Kainic Acid; Male; Microscopy, Electron; Nerve Degeneration; Neurotoxins; Organ of Corti; Rats; Rats, Long-Evans; Reaction Time; Trimetazidine; Vasodilator Agents; Vestibulocochlear Nerve	1999
Maturation of NADPH-d activity in the rat's barrel-field cortex and its relationship to cytochrome oxidase activity. Experimental neurology, 1999, Volume: 156, Issue:2 Topics: Animals; Biomarkers; Electron Transport Complex IV; Enzyme Induction; Excitatory Amino Acid Agonists; Fetal Proteins; Gene Expression Regulation, Developmental; Kainic Acid; Morphogenesis; NADPH Dehydrogenase; Nerve Degeneration; Nerve Tissue Proteins; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxygen Consumption; Rats; Rats, Wistar; Somatosensory Cortex; Vibrissae	1999
Fimbria-fornix transection and excitotoxicity produce similar neurodegeneration in the septum. Neuroscience, 1999, Volume: 88, Issue:4 Topics: Animals; Denervation; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Septum Pellucidum	1999
Expression of C5a receptor in mouse brain: role in signal transduction and neurodegeneration. Neuroscience, 1999, Volume: 88, Issue:4 Topics: Animals; Brain; Brain Diseases; Cells, Cultured; Complement C5a; Humans; Kainic Acid; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Nerve Degeneration; Neuroglia; Neurons; Receptors, Complement; Recombinant Proteins; RNA, Messenger; Signal Transduction	1999
Prostate apoptosis response-4 production in synaptic compartments following apoptotic and excitotoxic insults: evidence for a pivotal role in mitochondrial dysfunction and neuronal degeneration. Journal of neurochemistry, 1999, Volume: 72, Issue:6 Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain; Carrier Proteins; Caspases; Cell Survival; Cells, Cultured; Dendrites; Female; Gene Expression Regulation; Glutamic Acid; Hippocampus; Intracellular Signaling Peptides and Proteins; Kainic Acid; Male; Mitochondria; Nerve Degeneration; Neurites; Neurons; Oligodeoxyribonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Synapses; Synaptosomes	1999
Long-term increase of Sp-1 transcription factors in the hippocampus after kainic acid treatment. Brain research. Molecular brain research, 1999, May-21, Volume: 69, Issue:1 Topics: Animals; Antibodies; Brain Chemistry; Disease Models, Animal; DNA Primers; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Gene Expression; Kainic Acid; Male; Mossy Fibers, Hippocampal; Nerve Degeneration; Protein Binding; Rats; Rats, Inbred F344; Sp1 Transcription Factor	1999
Expression of human apolipoprotein E3 or E4 in the brains of Apoe-/- mice: isoform-specific effects on neurodegeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Jun-15, Volume: 19, Issue:12 Topics: Aging; Alzheimer Disease; Animals; Apolipoprotein E3; Apolipoprotein E4; Apolipoproteins E; Brain Chemistry; Dendrites; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Agonists; Fluorescent Antibody Technique; Gene Expression Regulation, Developmental; Genotype; Humans; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Neurotoxins; Presynaptic Terminals; RNA, Messenger; Synaptophysin	1999
Interleukin-1beta immunoreactivity and microglia are enhanced in the rat hippocampus by focal kainate application: functional evidence for enhancement of electrographic seizures. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Jun-15, Volume: 19, Issue:12 Topics: Animals; Antibodies; Anticonvulsants; Antirheumatic Agents; Bicuculline; Cell Count; Electroencephalography; Enzyme-Linked Immunosorbent Assay; Epilepsy; Excitatory Amino Acid Agonists; GABA Antagonists; Glutamic Acid; Hippocampus; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Kainic Acid; Male; Microglia; Nerve Degeneration; Neurons; Piperazines; Rats; Rats, Sprague-Dawley; Sialoglycoproteins	1999
Kainic acid-induced inducible cyclooxygenase and c-Jun phosphorylation in the rat hippocampal formation. Brain research, 1999, Jul-31, Volume: 836, Issue:1-2 Topics: Animals; Cyclooxygenase 2; Enzyme Induction; Hippocampus; Isoenzymes; Kainic Acid; Male; Nerve Degeneration; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar	1999
Immunohistochemical localization of interleukin-1beta, interleukin-1 receptor antagonist and interleukin-1beta converting enzyme/caspase-1 in the rat brain after peripheral administration of kainic acid. Neuroscience, 1999, Volume: 93, Issue:3 Topics: Animals; Apoptosis; Brain Chemistry; Caspase 1; Enzyme Induction; Excitatory Amino Acid Agonists; Gene Expression Regulation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Kainic Acid; Male; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Rats; Rats, Sprague-Dawley; Sialoglycoproteins	1999
NMDA and non-NMDA receptor-mediated excitotoxicity are potentiated in cultured striatal neurons by prior chronic depolarization. Experimental neurology, 1999, Volume: 159, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cells, Cultured; Corpus Striatum; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Fetus; GluK2 Kainate Receptor; GluK3 Kainate Receptor; Kainic Acid; Membrane Potentials; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Potassium Chloride; Pregnancy; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate	1999
Ischaemic pre-conditioning in organotypic hippocampal slice cultures is inversely correlated to the induction of the 72 kDa heat shock protein (HSP72). Brain research, 1999, Oct-23, Volume: 845, Issue:2 Topics: Animals; Brain Ischemia; Excitatory Amino Acid Agonists; Glutamic Acid; Heat-Shock Proteins; Hippocampus; HSP72 Heat-Shock Proteins; Ischemic Preconditioning; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	1999
Neuronal death and blood-brain barrier breakdown after excitotoxic injury are independent processes. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Nov-15, Volume: 19, Issue:22 Topics: Animals; Blood-Brain Barrier; Cell Death; Cell Survival; Heterozygote; Hippocampus; Kainic Acid; Male; Mice; Mice, Knockout; Nerve Degeneration; Neurons; Neurotoxins; Plasminogen; Tissue Plasminogen Activator	1999
Endogenous adenosine protects CA1 neurons from kainic acid-induced neuronal cell loss in the rat hippocampus. The European journal of neuroscience, 1999, Volume: 11, Issue:10 Topics: Adenosine; Animals; Apoptosis; Disease Models, Animal; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Hippocampus; Histocompatibility Antigens Class II; Injections, Intraventricular; Kainic Acid; Macrophage-1 Antigen; Male; Microtubule-Associated Proteins; Nerve Degeneration; Neuroglia; Neurons; Phosphorylation; Proto-Oncogene Proteins c-jun; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline	1999
A global hypoxia preconditioning model: neuroprotection against seizure-induced specific gravity changes (edema) and brain damage in rats. Brain research. Brain research protocols, 1999, Volume: 4, Issue:3 Topics: Animals; Brain Edema; Disease Models, Animal; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Hypoxia, Brain; Ischemic Preconditioning; Kainic Acid; Male; Nerve Degeneration; Rats; Rats, Wistar; Specific Gravity	1999
Mutually protective actions of kainic acid epileptic preconditioning and sublethal global ischemia on hippocampal neuronal death: involvement of adenosine A1 receptors and K(ATP) channels. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1999, Volume: 19, Issue:12 Topics: Animals; Disease Models, Animal; DNA Fragmentation; Epilepsy; Glyburide; Hippocampus; In Situ Nick-End Labeling; Ischemic Attack, Transient; Ischemic Preconditioning; Kainic Acid; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Phenylisopropyladenosine; Potassium Channels; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Purinergic P1; Time Factors; Xanthines	1999
Nuclear factor kappa B-mediated kainate neurotoxicity in the rat and hamster hippocampus. Neuroscience, 1999, Volume: 94, Issue:1 Topics: Animals; Cell Death; Cell Nucleus; Cricetinae; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; Kainic Acid; Mesocricetus; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; NF-kappa B; Rats; Rats, Sprague-Dawley	1999
AMPA receptor calcium permeability, GluR2 expression, and selective motoneuron vulnerability. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Jan-01, Volume: 20, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amyotrophic Lateral Sclerosis; Animals; Calcium; Cell Survival; Cells, Cultured; Excitatory Amino Acid Agonists; Gene Expression; Kainic Acid; Motor Neurons; Nerve Degeneration; Neurotoxins; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord	2000
Cynandione A from Cynanchum wilfordii protects cultured cortical neurons from toxicity induced by H2O2, L-glutamate, and kainate. Journal of neuroscience research, 2000, Jan-15, Volume: 59, Issue:2 Topics: Animals; Antioxidants; Biphenyl Compounds; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Fetus; Glutamic Acid; Hydrogen Peroxide; Kainic Acid; Nerve Degeneration; Neuroglia; Neurons; Neuroprotective Agents; Oxidants; Oxidative Stress; Plant Roots; Plants, Medicinal; Rats; Rats, Sprague-Dawley	2000
Mapping of the progressive metabolic changes occurring during the development of hippocampal sclerosis in a model of mesial temporal lobe epilepsy. Brain research, 2000, Jan-10, Volume: 852, Issue:2 Topics: Animals; Behavior, Animal; Brain Mapping; Carbon Radioisotopes; Deoxyglucose; Disease Models, Animal; Energy Metabolism; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Glucose; Hippocampus; Kainic Acid; Male; Mice; Microinjections; Nerve Degeneration; Sclerosis	2000
Genetic dissection of the signals that induce synaptic reorganization. Experimental neurology, 2000, Volume: 161, Issue:1 Topics: Animals; Dentate Gyrus; Epilepsy; Excitatory Amino Acid Agonists; GAP-43 Protein; Gene Expression; In Situ Hybridization; Kainic Acid; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Mossy Fibers, Hippocampal; Nerve Degeneration; Proto-Oncogene Proteins c-fos; RNA, Messenger; Seizures; Signal Transduction; Species Specificity; Synapses	2000
Differential expression of S100beta and glial fibrillary acidic protein in the hippocampus after kainic acid-induced lesions and mossy fiber sprouting in adult rat. Experimental neurology, 2000, Volume: 161, Issue:1 Topics: Age Factors; Animals; Blotting, Northern; Calcium-Binding Proteins; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Kainic Acid; Male; Mossy Fibers, Hippocampal; Nerve Degeneration; Nerve Growth Factors; Rats; Rats, Sprague-Dawley; RNA, Messenger; S100 Calcium Binding Protein beta Subunit; S100 Proteins	2000
Intracerebral injection of caspase-3 inhibitor prevents neuronal apoptosis after kainic acid-evoked status epilepticus. Brain research. Molecular brain research, 2000, Feb-22, Volume: 75, Issue:2 Topics: Animals; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; DNA Fragmentation; Enzyme Induction; Enzyme Inhibitors; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Neurons; Oligopeptides; Rats; Rats, Sprague-Dawley; Status Epilepticus	2000
Do GABAergic circuitries play a critical role in the regulation of seizure-induced neuronal damage and synaptic reorganization in the rat hippocampus? Electroencephalography and clinical neurophysiology. Supplement, 1999, Volume: 50 Topics: Afferent Pathways; Animals; Brain Chemistry; Cell Survival; Denervation; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Fornix, Brain; gamma-Aminobutyric Acid; Hippocampus; Kainic Acid; Mossy Fibers, Hippocampal; Nerve Degeneration; Perforant Pathway; Rats; Status Epilepticus; Synapses	1999
Neuroprotection by metabotropic glutamate receptor agonists on kainate-induced degeneration of motor neurons in spinal cord slices from adult rat. Neuropharmacology, 2000, Mar-03, Volume: 39, Issue:5 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Cell Survival; Choline O-Acetyltransferase; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Situ Nick-End Labeling; In Vitro Techniques; Kainic Acid; Male; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord	2000
Differential vulnerabilities of substantia nigra catecholamine neurons to excitatory amino acid-induced degeneration in rat midbrain slices. Experimental neurology, 2000, Volume: 162, Issue:1 Topics: Animals; Catecholamines; Cell Death; Dendrites; Excitatory Amino Acid Agonists; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase	2000
Kainic acid-induced seizures cause neuronal death in infant rats pretreated with lipopolysaccharide. Neuroreport, 2000, Feb-28, Volume: 11, Issue:3 Topics: Animals; Animals, Newborn; Cell Survival; Drug Synergism; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Lipopolysaccharides; Mossy Fibers, Hippocampal; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Reference Values; Seizures	2000
Increased expression of mRNA encoding interleukin-1beta and caspase-1, and the secreted isoform of interleukin-1 receptor antagonist in the rat brain following systemic kainic acid administration. Journal of neuroscience research, 2000, Apr-15, Volume: 60, Issue:2 Topics: Animals; Apoptosis; Brain; Caspase 1; Excitatory Amino Acid Agonists; In Situ Hybridization; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-1beta; Kainic Acid; Male; Microglia; Nerve Degeneration; Neurotoxins; Peptide Fragments; Polymerase Chain Reaction; Protein Isoforms; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sialoglycoproteins; Time Factors	2000
Systemic administration of domoic acid-induced spinal cord lesions in neonatal rats. The journal of spinal cord medicine, 2000,Spring, Volume: 23, Issue:1 Topics: Animals; Animals, Newborn; Dose-Response Relationship, Drug; Electroencephalography; Extremities; Injections, Subcutaneous; Kainic Acid; Nerve Degeneration; Neuromuscular Depolarizing Agents; Neurotoxins; Paralysis; Rats; Rats, Sprague-Dawley; Spinal Cord; Tremor	2000
Temporal progression of kainic acid induced neuronal and myelin degeneration in the rat forebrain. Brain research, 2000, May-02, Volume: 864, Issue:1 Topics: Amygdala; Animals; Basal Ganglia; Coloring Agents; Denervation; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Agonists; Female; Fluorescent Dyes; Glutamic Acid; Hippocampus; Hypothalamus; Kainic Acid; Myelin Sheath; Nerve Degeneration; Neurons; Neurotoxins; Olfactory Pathways; Parietal Lobe; Phosphates; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Status Epilepticus; Thalamus; Time Factors	2000
Intracellular glutathione levels determine cerebellar granule neuron sensitivity to excitotoxic injury by kainic acid. Brain research, 2000, Apr-17, Volume: 862, Issue:1-2 Topics: Animals; Cell Survival; Cerebellum; Excitatory Amino Acid Agonists; Fluoresceins; Glutamic Acid; Glutathione; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species	2000
Magnetic resonance imaging follow-up of progressive hippocampal changes in a mouse model of mesial temporal lobe epilepsy. Epilepsia, 2000, Volume: 41, Issue:6 Topics: Animals; Brain Diseases; Disease Models, Animal; Epilepsy, Temporal Lobe; Follow-Up Studies; Functional Laterality; Gadolinium; Hippocampus; Image Enhancement; Kainic Acid; Magnetic Resonance Imaging; Mice; Microinjections; Nerve Degeneration; Sclerosis; Seizures; Status Epilepticus	2000
Presence of apolipoprotein E immunoreactivity in degenerating neurones of mice is dependent on the severity of kainic acid-induced lesion. Brain research, 2000, Jun-23, Volume: 868, Issue:2 Topics: Animals; Apolipoproteins E; Behavior, Animal; Brain; Kainic Acid; Male; Mice; Mice, Inbred Strains; Nerve Degeneration; Neurodegenerative Diseases; Neuroglia; Neurons; Neurotoxins; Seizures	2000
Gonadal hormones affect neuronal vulnerability to excitotoxin-induced degeneration. Journal of neurocytology, 1999, Volume: 28, Issue:9 Topics: Animals; Excitatory Amino Acid Agonists; Female; Gonadal Steroid Hormones; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Neurotoxins; Orchiectomy; Ovariectomy; Ovary; Rats; Rats, Wistar; Testis	1999
Glucocorticoids exacerbate insult-induced declines in metabolism in selectively vulnerable hippocampal cell fields. Brain research, 2000, Jul-07, Volume: 870, Issue:1-2 Topics: Animals; Dentate Gyrus; Energy Metabolism; Excitatory Amino Acid Agonists; Glucocorticoids; Kainic Acid; Male; Necrosis; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Stress, Physiological	2000
Deafness induced up-regulation of GluR2/3 and NR1 in the spiral ganglion cells of the rat cochlea. Neuroreport, 2000, Aug-03, Volume: 11, Issue:11 Topics: Age Factors; Animals; Animals, Newborn; Cell Count; Deafness; Kainic Acid; Nerve Degeneration; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Spiral Ganglion; Up-Regulation	2000
Enhanced seizures and hippocampal neurodegeneration following kainic acid-induced seizures in metallothionein-I + II-deficient mice. The European journal of neuroscience, 2000, Volume: 12, Issue:7 Topics: Animals; Apoptosis; Astrocytes; Caspase 1; Caspase 3; Caspases; DNA, Single-Stranded; Epilepsy; Excitatory Amino Acid Agonists; Female; Gene Expression Regulation, Enzymologic; Glial Fibrillary Acidic Protein; Granulocyte-Macrophage Colony-Stimulating Factor; Hippocampus; In Situ Nick-End Labeling; Kainic Acid; Male; Malondialdehyde; Metallothionein; Metallothionein 3; Mice; Mice, Inbred Strains; Mice, Knockout; Microglia; Nerve Degeneration; Nerve Tissue Proteins; NF-kappa B; Nitrogen; Oxidative Stress; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Seizures; Superoxide Dismutase; Tyrosine; Zinc	2000
Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration. Brain research, 2000, Aug-25, Volume: 874, Issue:2 Topics: Animals; Brain; Fluoresceins; Fluorescent Antibody Technique; Fluorescent Dyes; Kainic Acid; Male; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Staining and Labeling	2000
Gene therapies that enhance hippocampal neuron survival after an excitotoxic insult are not equivalent in their ability to maintain synaptic transmission. Experimental neurology, 2000, Volume: 166, Issue:1 Topics: Animals; Apoptosis Regulatory Proteins; Carrier Proteins; Cell Survival; Chromogenic Compounds; Dentate Gyrus; Excitatory Postsynaptic Potentials; Genetic Therapy; Glucose Transporter Type 1; Hippocampus; Kainic Acid; Male; Monosaccharide Transport Proteins; Mossy Fibers, Hippocampal; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley; Synaptic Transmission	2000
Kainic acid lesions to the lateral tegmental field of medulla: effects on cough, expiration and aspiration reflexes in anesthetized cats. Physiological research, 2000, Volume: 49, Issue:3 Topics: Anesthesia; Animals; Blood Pressure; Cats; Cough; Decerebrate State; Electromyography; Excitatory Amino Acid Agonists; Female; Fourth Ventricle; Kainic Acid; Male; Medulla Oblongata; Mesencephalon; Nerve Degeneration; Physical Stimulation; Reflex; Respiratory Mechanics; Reticular Formation	2000
Long-term increase of GluR2 alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor subunit in the dispersed dentate gyrus after intrahippocampal kainate injection in the mouse. Neuroscience, 2000, Volume: 101, Issue:1 Topics: Animals; Dentate Gyrus; Disease Models, Animal; Epilepsy; Kainic Acid; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Rats; Rats, Wistar; Receptors, AMPA; Time Factors	2000
Presenilin-1 regulates the neuronal threshold to excitotoxicity both physiologically and pathologically. Proceedings of the National Academy of Sciences of the United States of America, 2000, Nov-07, Volume: 97, Issue:23 Topics: Alzheimer Disease; Animals; Brain; Cells, Cultured; Disease Models, Animal; Excitatory Amino Acid Agonists; Gene Expression; Humans; Infarction, Middle Cerebral Artery; Kainic Acid; Membrane Proteins; Mice; Mice, Knockout; Mice, Transgenic; N-Methylaspartate; Nerve Degeneration; Neurons; Presenilin-1	2000
Seizure-induced neuronal death is associated with induction of c-Jun N-terminal kinase and is dependent on genetic background. Brain research, 2000, Nov-24, Volume: 884, Issue:1--2 Topics: Animals; Cell Death; Epilepsy; Hippocampus; JNK Mitogen-Activated Protein Kinases; Kainic Acid; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Nerve Degeneration; Neurons; Neurotoxins; Phosphorylation; Proto-Oncogene Proteins c-jun; Seizures; Time Factors	2000
Inhibition of kainic acid induced expression of interleukin-1 beta and interleukin-1 receptor antagonist mRNA in the rat brain by NMDA receptor antagonists. Brain research. Molecular brain research, 2000, Dec-28, Volume: 85, Issue:1-2 Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Epilepsies, Myoclonic; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression; In Situ Hybridization; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Kainic Acid; Male; Microglia; Nerve Degeneration; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sialoglycoproteins	2000
In vivo, the direct and seizure-induced neuronal cytotoxicity of kainate and AMPA is modified by the non-competitive antagonist, GYKI 52466. Brain research, 2001, Jan-26, Volume: 890, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cell Death; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Nerve Degeneration; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Seizures	2001
Protein deimination in the rat brain after kainate administration: citrulline-containing proteins as a novel marker of neurodegeneration. Neuroscience letters, 2001, Feb-16, Volume: 299, Issue:1-2 Topics: Animals; Biomarkers; Citrulline; Disease Models, Animal; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Hydrolases; Imines; Kainic Acid; Microtubule-Associated Proteins; Nerve Degeneration; Nerve Tissue Proteins; Neuroglia; Neurons; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Rats; Rats, Wistar; Telencephalon	2001
Regulation of X-chromosome-linked inhibitor of apoptosis protein in kainic acid-induced neuronal death in the rat hippocampus. Molecular and cellular neurosciences, 2001, Volume: 17, Issue:2 Topics: Animals; Apoptosis; Biomarkers; Caspase 3; Caspases; Cell Death; Cells, Cultured; Excitatory Amino Acid Agonists; Gene Expression Regulation, Developmental; Genetic Linkage; Hippocampus; In Situ Nick-End Labeling; Kainic Acid; Male; Nerve Degeneration; Neurons; Proteins; Rats; RNA, Messenger; X Chromosome; X-Linked Inhibitor of Apoptosis Protein	2001
Interleukin-6 deficiency reduces the brain inflammatory response and increases oxidative stress and neurodegeneration after kainic acid-induced seizures. Neuroscience, 2001, Volume: 102, Issue:4 Topics: Animals; Apoptosis; Blood-Brain Barrier; Encephalitis; Epilepsy; Excitatory Amino Acid Agonists; Gene Expression; Gliosis; Hippocampus; In Situ Nick-End Labeling; Interleukin-6; Kainic Acid; Macrophages; Metallothionein; Mice; Mice, Knockout; Microglia; Nerve Degeneration; Oxidative Stress; Seizures; Superoxide Dismutase	2001
Decreased epileptic susceptibility correlates with neuropeptide Y overexpression in a model of tolerance to excitotoxicity. Brain research, 2001, Mar-16, Volume: 894, Issue:2 Topics: Adaptation, Physiological; Animals; Behavior, Animal; Cell Death; Disease Models, Animal; Disease Susceptibility; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Nerve Degeneration; Neuropeptide Y; Neurotoxins; Pyramidal Cells; Rats; Rats, Wistar	2001
Pharmacology and neuroprotective actions of mGlu receptor ligands. Developmental medicine and child neurology. Supplement, 2001, Volume: 86 Topics: Amino Acids; Brain; Brain Ischemia; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Glycine; Hippocampus; Humans; Kainic Acid; Ligands; Nerve Degeneration; Neuroprotective Agents; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate	2001
Expression of neuropsin in oligodendrocytes after injury to the CNS. Neuroscience research, 2001, Volume: 39, Issue:4 Topics: Animals; Axons; Brain Injuries; Excitatory Amino Acid Agonists; Eye Enucleation; Hippocampus; Immunohistochemistry; Kainic Acid; Kallikreins; Mice; Myelin Basic Protein; Nerve Degeneration; Oligodendroglia; Optic Nerve; Pyramidal Cells; RNA, Messenger; Serine Endopeptidases	2001
Protective effect of the antioxidant 6-ethoxy-2,2-pentamethylen-1,2-dihydroquinoline (S 33113) in models of cerebral neurodegeneration. European journal of pharmacology, 2001, Mar-23, Volume: 416, Issue:1-2 Topics: Alloxan; Animals; Antioxidants; Body Temperature; Brain Ischemia; Cell Survival; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Hippocampus; Hyperglycemia; Injections, Intraventricular; Kainic Acid; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Nerve Degeneration; Neurons; Quinolines; Rats; Rats, Wistar; Rectum; Survival Rate; tert-Butylhydroperoxide	2001
Alpha-synuclein protein is not scavenged in neuronal loss induced by kainic acid or focal ischemia. Brain research, 2001, Apr-13, Volume: 898, Issue:1 Topics: alpha-Synuclein; Animals; Brain; Brain Ischemia; Cell Death; Kainic Acid; Male; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Rats; Rats, Wistar; Synucleins; Time Factors	2001
Death of motoneurons induced by trophic deprivation or by excitotoxicity is not prevented by overexpression of SMN. Neurobiology of disease, 2001, Volume: 8, Issue:2 Topics: Animals; Cell Survival; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Fetus; Genetic Vectors; Humans; Kainic Acid; Lentivirus; Motor Neurons; Nerve Degeneration; Nerve Growth Factors; Nerve Tissue Proteins; Neurotoxins; Rats; RNA-Binding Proteins; RNA, Antisense; SMN Complex Proteins; Spinal Cord; Spinal Muscular Atrophies of Childhood; Survival of Motor Neuron 1 Protein; Transduction, Genetic	2001
Activated astrocytes in areas of kainate-induced neuronal injury upregulate the expression of the metabotropic glutamate receptors 2/3 and 5. Experimental brain research, 2001, Volume: 137, Issue:1 Topics: Adaptation, Physiological; Animals; Astrocytes; Brain Injuries; COS Cells; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Gliosis; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Mice; Nerve Degeneration; Nerve Regeneration; Neuronal Plasticity; Pyramidal Cells; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Up-Regulation	2001
Disruption of the GluR2-NSF interaction protects primary hippocampal neurons from ischemic stress. Molecular and cellular neurosciences, 2001, Volume: 17, Issue:4 Topics: Animals; Brain Ischemia; Calcium; Carrier Proteins; Cell Death; Cells, Cultured; Excitatory Amino Acid Agonists; Gene Expression; Glucose; Hippocampus; Kainic Acid; N-Ethylmaleimide-Sensitive Proteins; Nerve Degeneration; Neurons; Receptors, AMPA; Recombinant Proteins; Transfection; Vesicular Transport Proteins	2001
Brain aromatase is neuroprotective. Journal of neurobiology, 2001, Jun-15, Volume: 47, Issue:4 Topics: Animals; Aromatase; Aromatase Inhibitors; Brain; Cell Death; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Fadrozole; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Orchiectomy; Testosterone	2001
Heme oxgenase-1 is expressed in viable astrocytes and microglia but in degenerating pyramidal neurons in the kainate-lesioned rat hippocampus. Experimental brain research, 2001, Volume: 137, Issue:3-4 Topics: Animals; Astrocytes; Blotting, Western; Excitatory Amino Acid Agonists; Heme Oxygenase (Decyclizing); Hippocampus; Immunohistochemistry; Kainic Acid; Male; Microglia; Microscopy, Electron; Nerve Degeneration; Pyramidal Cells; Rats; Rats, Wistar	2001
Glutamic acid decarboxylase-67-positive hippocampal interneurons undergo a permanent reduction in number following kainic acid-induced degeneration of ca3 pyramidal neurons. Experimental neurology, 2001, Volume: 169, Issue:2 Topics: Animals; Cell Survival; Dentate Gyrus; Glutamate Decarboxylase; Hippocampus; Immunohistochemistry; Injections, Intraventricular; Interneurons; Isoenzymes; Kainic Acid; Male; Nerve Degeneration; Pyramidal Cells; Rats; Rats, Inbred F344; Time Factors	2001
Enhanced but fragile inhibition in the dentate gyrus in vivo in the kainic acid model of temporal lobe epilepsy: a study using current source density analysis. Neuroscience, 2001, Volume: 104, Issue:2 Topics: Animals; Bicuculline; Dentate Gyrus; Disease Models, Animal; Electric Stimulation; Entorhinal Cortex; Epilepsy, Temporal Lobe; Evoked Potentials; Excitatory Amino Acid Agonists; GABA Antagonists; Kainic Acid; Male; Membrane Potentials; Mossy Fibers, Hippocampal; Nerve Degeneration; Neural Inhibition; Neuronal Plasticity; Neurons; Perforant Pathway; Rats; Rats, Long-Evans; Synaptic Transmission	2001
Increased expression of Fas (CD95/APO-1) in adult rat brain after kainate-induced seizures. Neuroreport, 2001, Jul-03, Volume: 12, Issue:9 Topics: Animals; Brain; Cell Death; Excitatory Amino Acid Agonists; fas Receptor; Immunohistochemistry; In Situ Nick-End Labeling; Kainic Acid; Male; Nerve Degeneration; Neurodegenerative Diseases; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seizures; Tumor Suppressor Protein p53	2001
Differential roles of cyclooxygenase isoforms after kainic acid-induced prostaglandin E(2) production and neurodegeneration in cortical and hippocampal cell cultures. Brain research, 2001, Jul-20, Volume: 908, Issue:1 Topics: Animals; Astrocytes; Bisbenzimidazole; Cells, Cultured; Cerebral Cortex; Coloring Agents; Cyclooxygenase Inhibitors; Dinoprostone; Excitatory Amino Acid Agonists; Fetus; Fluorescent Dyes; Gene Expression Regulation, Enzymologic; Hippocampus; Kainic Acid; L-Lactate Dehydrogenase; Mice; Nerve Degeneration; Neurons; Propidium; Prostaglandin-Endoperoxide Synthases; Protein Isoforms	2001
Electroconvulsive shock exposure prevents neuronal apoptosis after kainic acid-evoked status epilepticus. Brain research. Molecular brain research, 2001, Jul-13, Volume: 91, Issue:1-2 Topics: Animals; Apoptosis; bcl-X Protein; Biomarkers; DNA Fragmentation; Electroconvulsive Therapy; Entorhinal Cortex; Excitatory Amino Acid Agonists; Gene Expression; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Neurons; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; RNA, Messenger; Status Epilepticus	2001
Downregulation of free ubiquitin: a novel mechanism of p53 stabilization and neuronal cell death. Brain research. Molecular brain research, 2001, Jul-13, Volume: 91, Issue:1-2 Topics: Animals; Brain; Camptothecin; Cell Death; Cells, Cultured; DNA Damage; Down-Regulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; In Situ Nick-End Labeling; Kainic Acid; Male; Nerve Degeneration; Neurons; Nuclear Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53; Ubiquitins	2001
Lactate dehydrogenase release is facilitated by brief sonication of rat hippocampal slices and isolated retinas following acute neuronal damage. Journal of neuroscience methods, 2001, Jul-15, Volume: 108, Issue:1 Topics: Acute Disease; Animals; Brain Injuries; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hippocampus; Iodoacetates; Kainic Acid; L-Lactate Dehydrogenase; Nerve Degeneration; Neurochemistry; Neurons; Neurotoxins; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Retina; Sonication	2001
Dynamic induction of the long pentraxin PTX3 in the CNS after limbic seizures: evidence for a protective role in seizure-induced neurodegeneration. Neuroscience, 2001, Volume: 105, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; C-Reactive Protein; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Genetic Predisposition to Disease; Immunohistochemistry; Kainic Acid; Limbic System; Male; Mice; Mice, Knockout; Nerve Degeneration; Neurons; Neuroprotective Agents; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Serum Amyloid P-Component	2001
Kainate-induced epilepsy alters protein expression of AMPA receptor subunits GluR1, GluR2 and AMPA receptor binding protein in the rat hippocampus. Acta neuropathologica, 2001, Volume: 101, Issue:5 Topics: Animals; Carrier Proteins; Cell Survival; Dentate Gyrus; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Hippocampus; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Kainic Acid; Male; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neurotoxins; Rats; Receptors, AMPA	2001
Ibotenate injections into the pre- and parasubiculum provide partial protection against kainate-induced epileptic damage in layer III of rat entorhinal cortex. Epilepsia, 2001, Volume: 42, Issue:7 Topics: Animals; Convulsants; Disease Models, Animal; Entorhinal Cortex; Epilepsy; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Ibotenic Acid; Kainic Acid; Male; Nerve Degeneration; Neurons, Afferent; Neuroprotective Agents; Rats; Rats, Sprague-Dawley	2001
Kainic acid-induced substantia nigra seizure in rats: behavior, EEG and metabolism. Brain research, 2001, Aug-17, Volume: 911, Issue:1 Topics: Action Potentials; Animals; Behavior, Animal; Carbon Radioisotopes; Deoxyglucose; Electroencephalography; Energy Metabolism; Epilepsy; Excitatory Amino Acid Agonists; Glucose; Hippocampus; Kainic Acid; Nerve Degeneration; Neurons; Rats; Rats, Wistar; Substantia Nigra	2001
Subthalamic nucleus lesions reduce low frequency oscillatory firing of substantia nigra pars reticulata neurons in a rat model of Parkinson's disease. Brain research, 2001, Jun-15, Volume: 904, Issue:1 Topics: Action Potentials; Animals; Biological Clocks; Disease Models, Animal; Excitatory Amino Acid Agonists; Kainic Acid; Male; Nerve Degeneration; Neural Pathways; Neurons; Neurotoxins; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Substantia Nigra; Subthalamic Nucleus; Sympatholytics	2001
Dentate hilar mossy cells and somatostatin-containing neurons are immunoreactive for the alpha8 integrin subunit: characterization in normal and kainic acid-treated rats. Neuroscience, 2001, Volume: 105, Issue:3 Topics: Animals; Cell Adhesion; Cell Communication; Cell Compartmentation; Cell Count; Cell Death; Dendrites; Dentate Gyrus; Epilepsy; Excitatory Amino Acid Agonists; Extracellular Matrix; Immunohistochemistry; Integrin alpha Chains; Integrins; Kainic Acid; Male; Microscopy, Electron; Mossy Fibers, Hippocampal; Nerve Degeneration; Parvalbumins; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Somatostatin	2001
Alterations in cytochrome c oxidase activity and energy metabolites in response to kainic acid-induced status epilepticus. Brain research, 2001, Aug-31, Volume: 912, Issue:1 Topics: Adenosine Triphosphate; Amygdala; Animals; Antioxidants; Brain; Cerebral Cortex; Cyclic N-Oxides; Electron Transport Complex IV; Energy Metabolism; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Nerve Degeneration; Neurotoxins; Nitrogen Oxides; Oxidative Stress; Phosphocreatine; Rats; Reactive Oxygen Species; RNA, Messenger; Status Epilepticus; Vitamin E	2001
Dependence of excitotoxic neurodegeneration on mitochondrial aconitase inactivation. Journal of neurochemistry, 2001, Volume: 78, Issue:4 Topics: Aconitate Hydratase; Animals; Astrocytes; Cell Death; Cell Fractionation; Cells, Cultured; Enzyme Inhibitors; Fumarate Hydratase; Glucose; Kainic Acid; Metalloporphyrins; Mitochondria; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Oxygen; Paraquat; Rats; Superoxides	2001
Delayed induction of alpha B-crystallin in activated glia cells of hippocampus in kainic acid-treated mouse brain. Journal of neuroscience research, 2001, Sep-01, Volume: 65, Issue:5 Topics: Animals; Arginine; Astrocytes; Crystallins; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gliosis; Heat-Shock Proteins; Hippocampus; Immunohistochemistry; Indazoles; Kainic Acid; Male; Mice; Mice, Inbred BALB C; Molecular Chaperones; Neoplasm Proteins; Nerve Degeneration; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Seizures	2001
Domoic acid-induced neuronal damage in the rat hippocampus: changes in apoptosis related genes (bcl-2, bax, caspase-3) and microglial response. Journal of neuroscience research, 2001, Oct-15, Volume: 66, Issue:2 Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Convulsants; Gene Expression Profiling; Gene Expression Regulation; Genes, bcl-2; Hippocampus; Histocompatibility Antigens Class II; In Situ Hybridization; In Situ Nick-End Labeling; Kainic Acid; Macrophage-1 Antigen; Male; Marine Toxins; Microglia; Microscopy, Electron; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neurotoxins; Phagocytosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seizures; Time Factors; Up-Regulation	2001
Kainate excitotoxicity in organotypic hippocampal slice cultures: evidence for multiple apoptotic pathways. Brain research, 2001, Oct-19, Volume: 916, Issue:1-2 Topics: Amino Acid Chloromethyl Ketones; Animals; Animals, Newborn; Apoptosis; bcl-2-Associated X Protein; Brain Diseases; Caspase Inhibitors; Caspases; Cells, Cultured; Cyclosporine; Cytochrome c Group; Cytosol; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hippocampus; Immunohistochemistry; Kainic Acid; Membrane Potentials; Mitochondria; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyramidal Cells; Rats; RNA, Messenger	2001
Sustained, long-lasting inhibition of nitric oxide synthase aggravates the neural damage in some models of excitotoxic brain injury. Brain research bulletin, 2001, Sep-01, Volume: 56, Issue:1 Topics: Animals; Basal Nucleus of Meynert; Brain; Brain Injuries; Calcium Channel Blockers; Choline O-Acetyltransferase; Cholinergic Fibers; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamate Decarboxylase; Ibotenic Acid; Immunohistochemistry; Kainic Acid; Male; NADPH Dehydrogenase; Neostriatum; Nerve Degeneration; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Verapamil	2001
Ether fraction of methanol extracts of Gastrodia elata, a traditional medicinal herb, protects against kainic acid-induced neuronal damage in the mouse hippocampus. Neuroscience letters, 2001, Nov-13, Volume: 314, Issue:1-2 Topics: Animals; Dose-Response Relationship, Drug; Epilepsy; Ether; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Methanol; Mice; Mice, Inbred ICR; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Orchidaceae; Phytotherapy; Plant Extracts	2001
Memory retrieval impairment induced by hippocampal CA3 lesions is blocked by adrenocortical suppression. Nature neuroscience, 2001, Volume: 4, Issue:12 Topics: Adrenal Cortex; Animals; Corticosterone; Hippocampus; Hypothalamo-Hypophyseal System; Kainic Acid; Male; Maze Learning; Memory; Memory Disorders; Nerve Degeneration; Neural Inhibition; Neural Pathways; Pituitary-Adrenal System; Pyridines; Rats; Rats, Sprague-Dawley; Reaction Time	2001
Prevention of neurotoxin damage of 6-OHDA to dopaminergic nigral neuron by subthalamic nucleus lesions. Stereotactic and functional neurosurgery, 2000, Volume: 75, Issue:2-3 Topics: Afferent Pathways; Animals; Biomarkers; Dopamine; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Male; Medial Forebrain Bundle; Microinjections; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neurotoxins; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Substantia Nigra; Subthalamic Nucleus; Tyrosine 3-Monooxygenase; Ventral Tegmental Area	2000
Fetal hippocampal CA3 cell grafts transplanted to lesioned CA3 region of the adult hippocampus exhibit long-term survival in a rat model of temporal lobe epilepsy. Neurobiology of disease, 2001, Volume: 8, Issue:6 Topics: Aging; Animals; Biomarkers; Brain Tissue Transplantation; Bromodeoxyuridine; Cell Count; Epilepsy, Temporal Lobe; Fetal Tissue Transplantation; Graft Survival; Hippocampus; Immunohistochemistry; Kainic Acid; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Pyramidal Cells; Rats; Rats, Inbred F344	2001
Domoic acid neurotoxicity in cultured cerebellar granule neurons is controlled preferentially by the NMDA receptor Ca(2+) influx pathway. Brain research, 2002, Jan-04, Volume: 924, Issue:1 Topics: Aniline Compounds; Animals; Animals, Newborn; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cell Death; Cells, Cultured; Cerebellar Cortex; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Fluorescent Dyes; Kainic Acid; L-Lactate Dehydrogenase; Nerve Degeneration; Neuromuscular Depolarizing Agents; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium-Calcium Exchanger; Xanthenes	2002
Systemic administration of kainic acid in adult rat stimulates expression of the chemokine receptor CCR5 in the forebrain. Glia, 2002, Volume: 37, Issue:2 Topics: Animals; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Avian Proteins; Basigin; Blood Proteins; Brain Injuries; Chemokines; Excitatory Amino Acid Agonists; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Gliosis; Immunohistochemistry; Kainic Acid; Membrane Glycoproteins; Nerve Degeneration; Neuroglia; Neurons; Neurotoxins; Phosphopyruvate Hydratase; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, CCR5; RNA, Messenger; Up-Regulation	2002
Effect of an anticonvulsant drug on kainic acid-induced brain damage. Proceedings of the Western Pharmacology Society, 2001, Volume: 44 Topics: Animals; Anticonvulsants; Behavior, Animal; Brain Diseases; Cerebellar Cortex; Cerebellum; Dentate Gyrus; Excitatory Amino Acid Agonists; Kainic Acid; Male; Nerve Degeneration; Purkinje Cells; Rats; Rats, Wistar	2001
Dopamine D2 receptor signaling controls neuronal cell death induced by muscarinic and glutamatergic drugs. Molecular and cellular neurosciences, 2002, Volume: 19, Issue:2 Topics: Acetylcholine; Animals; Behavior, Animal; Cell Death; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Agonists; Female; Genotype; Glutamic Acid; Kainic Acid; Limbic System; Male; Mice; Mice, Knockout; Molecular Sequence Data; Muscarinic Agonists; Nerve Degeneration; Pilocarpine; Receptors, Dopamine D2; Receptors, Muscarinic; RNA, Messenger; Signal Transduction; Synaptic Transmission	2002
Arctigenin protects cultured cortical neurons from glutamate-induced neurodegeneration by binding to kainate receptor. Journal of neuroscience research, 2002, Apr-15, Volume: 68, Issue:2 Topics: Animals; Cells, Cultured; Cerebral Cortex; Free Radical Scavengers; Furans; Glutamic Acid; Kainic Acid; Lignans; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Peroxides; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid	2002
Volumetric structural magnetic resonance imaging (MRI) of the rat hippocampus following kainic acid (KA) treatment. Brain research, 2002, May-03, Volume: 934, Issue:2 Topics: Animals; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Astrocytes; Avian Proteins; Basigin; Benzoxazines; Blood Proteins; Brain Mapping; Cell Count; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Agonists; Fluoresceins; Fluorescent Dyes; Glial Fibrillary Acidic Protein; Gyrus Cinguli; Hippocampus; Immunohistochemistry; Kainic Acid; Lateral Ventricles; Magnetic Resonance Imaging; Male; Membrane Glycoproteins; Microglia; Nerve Degeneration; Organic Chemicals; Oxazines; Rats; Rats, Sprague-Dawley	2002
Increased vulnerability to kainate-induced seizures in utrophin-knockout mice. The European journal of neuroscience, 2002, Volume: 15, Issue:9 Topics: Animals; Cell Count; Cell Size; Cell Survival; Cytoskeletal Proteins; Dentate Gyrus; Dystrophin; Epilepsy; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Female; Genetic Predisposition to Disease; Genotype; Hypertrophy; Immunohistochemistry; Kainic Acid; Male; Membrane Proteins; Mice; Mice, Knockout; Nerve Degeneration; Neurons; RNA, Messenger; Up-Regulation; Utrophin	2002
Increased and type II-specific expression of peptidylarginine deiminase in activated microglia but not hyperplastic astrocytes following kainic acid-evoked neurodegeneration in the rat brain. Neuroscience letters, 2002, Jun-28, Volume: 326, Issue:2 Topics: Animals; Astrocytes; Blotting, Western; Brain; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Hydrolases; Hyperplasia; Immunohistochemistry; Kainic Acid; Microglia; Nerve Degeneration; Protein-Arginine Deiminase Type 2; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Time Factors	2002
Electrophysiological, behavioral and metabolical features of globus pallidus seizures induced by a microinjection of kainic acid in rats. Brain research, 2002, May-10, Volume: 935, Issue:1-2 Topics: Action Potentials; Animals; Behavior, Animal; Carbon Radioisotopes; Deoxyglucose; Energy Metabolism; Epilepsy; European Union; Excitatory Amino Acid Agonists; Functional Laterality; Globus Pallidus; Glucose; Kainic Acid; Male; Movement Disorders; Nerve Degeneration; Neural Pathways; Neurons; Rats; Rats, Wistar	2002
Downregulation of kainate receptors in the hippocampus following repeated seizures in immature rats. Brain research. Developmental brain research, 2002, Jun-30, Volume: 136, Issue:2 Topics: Animals; Animals, Newborn; Binding Sites; Down-Regulation; Drug Administration Schedule; Epilepsy; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Hippocampus; Kainic Acid; Learning; Male; Memory; Nerve Degeneration; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Synaptic Transmission	2002
Microglial activation and recruitment, but not proliferation, suffice to mediate neurodegeneration. Cell death and differentiation, 2002, Volume: 9, Issue:8 Topics: Animals; Biomarkers; Cell Death; Cell Division; Chemotaxis; Down-Regulation; Excitatory Amino Acid Agonists; Gliosis; Hippocampus; Immunohistochemistry; Kainic Acid; Macrophage Colony-Stimulating Factor; Male; Mice; Mice, Mutant Strains; Microglia; Nerve Degeneration; Pyramidal Cells; Tissue Plasminogen Activator	2002
Long-term sequelae of striatal kainate lesion. Brain research, 1978, Sep-08, Volume: 152, Issue:3 Topics: Acetylcholine; Animals; Choline; Choline O-Acetyltransferase; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Kainic Acid; Nerve Degeneration; Neurons; Pyrrolidines; Rats; Receptors, Muscarinic; Tyrosine 3-Monooxygenase	1978
Kainic acid injections result in degeneration of cochlear nucleus cells innervated by the auditory nerve. Science (New York, N.Y.), 1978, Dec-08, Volume: 202, Issue:4372 Topics: Animals; Brain Stem; Dose-Response Relationship, Drug; Glutamates; Guinea Pigs; Kainic Acid; Male; Nerve Degeneration; Neurotransmitter Agents; Pyrrolidines; Receptors, Neurotransmitter; Vestibulocochlear Nerve	1978
An animal model for Huntington's disease. Biological psychiatry, 1979, Volume: 14, Issue:2 Topics: Animals; Choline O-Acetyltransferase; Corpus Striatum; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Huntington Disease; Kainic Acid; Nerve Degeneration; Neural Pathways; Rats; Receptors, Neurotransmitter; Substantia Nigra; Tyrosine 3-Monooxygenase	1979
Evidence for a GABAergic projection from the substantia nigra to the ventromedial thalamus and to the superior colliculus of the rat. Brain research, 1979, Nov-02, Volume: 176, Issue:2 Topics: Animals; Choline O-Acetyltransferase; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Kainic Acid; Male; Nerve Degeneration; Neural Pathways; Rats; Substantia Nigra; Superior Colliculi; Thalamus; Tyrosine 3-Monooxygenase	1979
Ibotenic acid-induced neuronal degeneration: a morphological and neurochemical study. Experimental brain research, 1979, Volume: 37, Issue:2 Topics: Animals; Brain; Choline O-Acetyltransferase; Corpus Striatum; Dopamine; Enkephalins; Fluorescent Antibody Technique; Glutamate Decarboxylase; Glutamates; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Nerve Degeneration; Oxazoles; Rats; Serotonin; Substantia Nigra; Tyrosine 3-Monooxygenase	1979
Kainic acid toxicity and binding in the optic tectum. Progress in brain research, 1979, Volume: 51 Topics: Animals; Binding, Competitive; Columbidae; Glutamates; Kainic Acid; Nerve Degeneration; Neurotransmitter Agents; Optic Lobe, Nonmammalian; Pyrrolidines; Rats; Synaptic Transmission; Time Factors	1979
Kainic acid-induced neurotoxicity in the striatum: a histofluorescent study. Brain research, 1979, Jun-29, Volume: 169, Issue:3 Topics: Animals; Axonal Transport; Corpus Striatum; Dopamine; Hippocampus; Kainic Acid; Male; Microscopy, Fluorescence; Nerve Degeneration; Nerve Fibers; Pyrrolidines; Rats; Receptors, Dopamine	1979
Kainate-induced degeneration of neostriatal neurons: dependency upon corticostriatal tract. Brain research, 1978, Jan-13, Volume: 139, Issue:2 Topics: Animals; Cerebral Cortex; Corpus Striatum; Efferent Pathways; Glutamates; Huntington Disease; In Vitro Techniques; Kainic Acid; Male; Nerve Degeneration; Pyrrolidines; Rats	1978
Inhibitors of GABA metabolism: implications for Huntington's disease. Annals of neurology, 1977, Volume: 2, Issue:4 Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Aminocaproic Acid; Animals; Caudate Nucleus; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Huntington Disease; Kainic Acid; Male; Nerve Degeneration; Rats; Substantia Nigra; Transaminases; Valproic Acid	1977
The fate of synaptic receptors in the kainate-lesioned striatum. Brain research, 1978, Jan-27, Volume: 140, Issue:2 Topics: Animals; Axons; Corpus Striatum; Kainic Acid; Male; Nerve Degeneration; Pyrrolidines; Rats; Receptors, Neurotransmitter	1978
Localization of opiate receptors and enkephalins in the rat striatum in relationship with the nigrostriatal dopaminergic system: lesion studies. Brain research, 1978, Aug-04, Volume: 151, Issue:2 Topics: Animals; Binding Sites; Corpus Striatum; Dopamine; Endorphins; Enkephalins; Hydroxydopamines; Kainic Acid; Nerve Degeneration; Neural Pathways; Neurons; Rats; Receptors, Dopamine; Receptors, Opioid; Substantia Nigra	1978
Evidence for a hippocampal-septal glutamatergic pathway in the rat. Experimental neurology, 1979, Volume: 65, Issue:1 Topics: Acetylcholine; Animals; gamma-Aminobutyric Acid; Glutamates; Hippocampus; Kainic Acid; Nerve Degeneration; Neural Pathways; Pyramidal Tracts; Rats; Septal Nuclei; Synaptic Transmission	1979
Evidence suggesting secondary epileptogenic lesion after kainic acid: pre treatment with diazepam reduces distant but not local brain damage. Brain research, 1979, Apr-13, Volume: 165, Issue:2 Topics: Amygdala; Animals; Diazepam; Hippocampus; Kainic Acid; Nerve Degeneration; Neural Pathways; Premedication; Pyrrolidines; Rats; Seizures	1979
A new model of focal status epilepticus: intra-amygdaloid application of kainic acid elicits repetitive secondarily generalized convulsive seizures. Brain research, 1979, Mar-09, Volume: 163, Issue:1 Topics: Amygdala; Animals; Dose-Response Relationship, Drug; Evoked Potentials; Hippocampus; Kainic Acid; Male; Models, Neurological; Nerve Degeneration; Pyrrolidines; Rats; Seizures; Status Epilepticus	1979
Preservation of trapezoid body fibers after biochemical ablation of superior olives with kainic acid. Brain research, 1979, Sep-07, Volume: 173, Issue:1 Topics: Animals; Auditory Pathways; Axons; Cats; Cochlear Nerve; Kainic Acid; Nerve Degeneration; Nerve Fibers, Myelinated; Olivary Nucleus; Pyrrolidines	1979
Hippocampal lesions indicate differences between the excitotoxic properties of acidic amono acids. Brain research, 1979, Oct-19, Volume: 175, Issue:2 Topics: Animals; Glutamates; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Nerve Degeneration; Neural Pathways; Neurons; Oxazoles; Pyrrolidines; Rats	1979
Is there a selectivity of neuronal degeneration induced by intrastriatal injection of kainic acid? Brain research, 1979, Nov-30, Volume: 177, Issue:3 Topics: Acetylcholinesterase; Animals; Brain Mapping; Corpus Striatum; Dopamine; Female; gamma-Aminobutyric Acid; Kainic Acid; Male; Nerve Degeneration; Neural Pathways; Neurons; Pyrrolidines; Quinuclidinyl Benzilate; Rats	1979
Calbindin-D28K-containing neurons in animal models of neurodegeneration: possible protection from excitotoxicity. Brain research. Molecular brain research, 1992, Volume: 13, Issue:3 Topics: Animals; Basal Ganglia Diseases; Biogenic Amines; Calbindin 1; Calbindins; Calcium; Cell Survival; Disease Models, Animal; Kainic Acid; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neurotoxins; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; RNA, Messenger; S100 Calcium Binding Protein G	1992
Dissociation of nitric oxide generation and kainate-mediated neuronal degeneration in primary cultures of rat cerebellar granule cells. Neuropharmacology, 1992, Volume: 31, Issue:6 Topics: Animals; Arginine; Azo Compounds; Cell Death; Cells, Cultured; Cerebellum; Cyclic GMP; Kainic Acid; Kinetics; Magnesium; Nerve Degeneration; Neurons; Nitric Oxide; Nitroarginine; Rats; Rats, Wistar	1992
Neuronal loss or replacement in the injured adult cerebral neocortex induces extensive remodeling of intrinsic and afferent neural systems. Experimental neurology, 1992, Volume: 117, Issue:2 Topics: Afferent Pathways; Analysis of Variance; Animals; Axonal Transport; Cerebral Cortex; Choline O-Acetyltransferase; Female; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Nerve Regeneration; Neurons; Neurotoxins; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Sympathectomy	1992
Alteration of long-lasting structural and functional effects of kainic acid in the hippocampus by brief treatment with phenobarbital. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1992, Volume: 12, Issue:11 Topics: Animals; Hippocampus; Injections, Intraventricular; Kainic Acid; Kindling, Neurologic; Male; Nerve Degeneration; Nerve Fibers; Phenobarbital; Rats; Rats, Sprague-Dawley; Seizures; Synapses; Time Factors	1992
Ultrastructural and immunocytochemical studies of macrophages in an excitotoxin induced lesion in the rat brain. Journal fur Hirnforschung, 1992, Volume: 33, Issue:6 Topics: Animals; Antibodies, Monoclonal; Brain; Cerebral Cortex; Immunohistochemistry; Kainic Acid; Lectins; Macrophages; Male; Microscopy, Electron; Nerve Degeneration; Neurotoxins; Plant Lectins; Rats; Rats, Wistar	1992
Activation and re-expression of surface antigen in microglia following an epidural application of kainic acid in the rat brain. Journal of anatomy, 1992, Volume: 180 ( Pt 2) Topics: Animals; Antibodies, Monoclonal; Antigens, Surface; Brain; Hippocampus; Immunoenzyme Techniques; Kainic Acid; Macrophage-1 Antigen; Male; Microscopy, Electron; Nerve Degeneration; Neuroglia; Rats; Rats, Inbred Strains; Thalamic Nuclei	1992
Microwave-enhanced silver staining of degenerating neuronal processes. Acta neuropathologica, 1992, Volume: 84, Issue:2 Topics: Animals; Animals, Newborn; Axons; Brain; Brain Ischemia; Histocytochemistry; Kainic Acid; Microscopy, Electron; Microwaves; Nerve Degeneration; Nerve Endings; Neurons; Rats; Silver Staining	1992
Adrenalectomy potentiates immediate early gene expression in rat brain. Journal of neurochemistry, 1992, Volume: 58, Issue:6 Topics: Adrenalectomy; Animals; Brain; Brain Chemistry; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Gene Expression; Genes; Glucocorticoids; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Pentylenetetrazole; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Inbred Strains; RNA, Messenger; Transcription, Genetic	1992
Acromelic acid, a novel kainate analogue, induces long-lasting paraparesis with selective degeneration of interneurons in the rat spinal cord. Experimental neurology, 1992, Volume: 116, Issue:2 Topics: Animals; Behavior, Animal; Chronic Disease; Glial Fibrillary Acidic Protein; Immunohistochemistry; Interneurons; Kainic Acid; Male; Nerve Degeneration; Paraplegia; Rats; Rats, Inbred Strains; Spinal Cord	1992
Depletion of connexin43-immunoreactivity in astrocytes after kainic acid-induced lesions in rat brain. Neuroscience letters, 1991, Sep-02, Volume: 130, Issue:1 Topics: Animals; Astrocytes; Brain Diseases; Connexins; Immunohistochemistry; Kainic Acid; Male; Membrane Proteins; Nerve Degeneration; Rats; Rats, Inbred Strains; Thalamus	1991
A metabotropic glutamate receptor agonist does not mediate neuronal degeneration in cortical culture. Brain research, 1991, Oct-11, Volume: 561, Issue:2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebral Cortex; Cycloleucine; Embryo, Mammalian; Glutamates; Ibotenic Acid; Kainic Acid; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Receptors, Glutamate; Receptors, Neurotransmitter; Tetrodotoxin	1991
The inhibition of glutamine synthetase in rat corpus striatum in vitro by methionine sulfoximine increases the neurotoxic effects of kainate and N-methyl-D-aspartate. Neuroscience letters, 1991, Sep-02, Volume: 130, Issue:1 Topics: Animals; Cerebellum; Corpus Striatum; Drug Synergism; Female; Glutamate-Ammonia Ligase; Kainic Acid; Methionine Sulfoximine; N-Methylaspartate; Nerve Degeneration; Nervous System Diseases; Neuroglia; Phosphopyruvate Hydratase; Rats; Rats, Inbred Strains	1991
Excitotoxicity in the embryonic chick spinal cord. Annals of neurology, 1991, Volume: 30, Issue:6 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; beta-Alanine; Chick Embryo; Cyanobacteria Toxins; Dizocilpine Maleate; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Quinoxalines; Quisqualic Acid; Spinal Cord	1991
Abnormal distribution of phosphorylated neurofilaments in neuronal degeneration induced by kainic acid. Neuroscience letters, 1990, Oct-30, Volume: 119, Issue:1 Topics: Animals; Immunohistochemistry; Injections, Spinal; Intermediate Filaments; Kainic Acid; Male; Motor Neurons; Nerve Degeneration; Neurons; Phosphorylation; Rats; Rats, Inbred Strains; Reference Values; Spinal Cord; Staining and Labeling	1990
The kinetics and morphological characteristics of the macrophage-microglial response to kainic acid-induced neuronal degeneration. Neuroscience, 1991, Volume: 42, Issue:1 Topics: Animals; Blotting, Western; Female; Hippocampus; Immunohistochemistry; Injections; Kainic Acid; Kinetics; Macrophages; Male; Mice; Mice, Inbred BALB C; Nerve Degeneration; Neuroglia; Staining and Labeling; Stereotaxic Techniques	1991
Various Ca2+ entry blockers prevent glutamate-induced neurotoxicity. European journal of pharmacology, 1991, Dec-17, Volume: 209, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium Channel Blockers; Cerebellum; Dihydropyridines; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Isradipine; Kainic Acid; Nerve Degeneration; Nervous System Diseases; Nifedipine; Rats; Rats, Inbred Strains; Verapamil	1991
Response of retinal terminals to loss of postsynaptic target neurons in the dorsal lateral geniculate nucleus of the adult cat. The Journal of comparative neurology, 1992, Jan-15, Volume: 315, Issue:3 Topics: Animals; Cats; Geniculate Bodies; Kainic Acid; Nerve Degeneration; Neural Pathways; Neurons; Retina; Synapses; Visual Cortex	1992
Nutrition, neurotoxicants and age-related neurodegeneration. Neurotoxicology, 1991,Fall, Volume: 12, Issue:3 Topics: Aging; Amino Acids; Animals; Avoidance Learning; Brain Diseases; Diet; Dietary Proteins; Energy Intake; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Rats; Rats, Inbred F344; Risk Factors; Trimethyltin Compounds	1991
Role of the mesopontine area in the circling behavior induced by apomorphine in rats bearing unilateral lesion of the entopeduncular nucleus. Behavioural brain research, 1991, Oct-25, Volume: 45, Issue:1 Topics: Animals; Apomorphine; Brain Mapping; Corpus Striatum; Dominance, Cerebral; Globus Pallidus; Kainic Acid; Male; Motor Activity; Nerve Degeneration; Neural Pathways; Pons; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Superior Colliculi; Thalamic Nuclei	1991
Afferent and efferent connections of the mesencephalic cardioinhibitory area (CIM) in the cat. The Chinese journal of physiology, 1991, Volume: 34, Issue:3 Topics: Afferent Pathways; Animals; Brain Stem; Cats; Efferent Pathways; Female; Heart; Histocytochemistry; Horseradish Peroxidase; Kainic Acid; Male; Mesencephalon; Microinjections; Nerve Degeneration; Neurons, Afferent; Neurons, Efferent	1991
Non-NMDA antagonists protect against kainate more than AMPA toxicity in the rat hippocampus. Neuroscience letters, 1991, Dec-09, Volume: 133, Issue:2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains	1991
Magnesium sulphate subcutaneously injected protects against kainate-induced convulsions and neurodegeneration: in vivo study on the rat hippocampus. Neuroscience, 1991, Volume: 43, Issue:1 Topics: Animals; Convulsants; Hippocampus; In Vitro Techniques; Injections, Subcutaneous; Kainic Acid; Magnesium Sulfate; Male; Nerve Degeneration; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Seizures	1991
Neuroprotectant effects of LY274614, a structurally novel systemically active competitive NMDA receptor antagonist. Journal of neural transmission. General section, 1991, Volume: 85, Issue:2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Female; Ibotenic Acid; Isoquinolines; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Quisqualic Acid; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	1991
Nerve cell death induced in vivo by kainic acid and quinolinic acid does not involve apoptosis. Neuroreport, 1991, Volume: 2, Issue:11 Topics: Animals; Calcium; Cell Death; DNA; Electrophoresis, Agar Gel; Gene Expression Regulation; Hippocampus; Kainic Acid; Male; Methylprednisolone; Nerve Degeneration; Neurons; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	1991
Selectivity of kainic acid as a neurotoxin within the dorsal lateral geniculate nucleus of the cat: a model for transneuronal retrograde degeneration. Journal of neurocytology, 1991, Volume: 20, Issue:5 Topics: Animals; Cats; Disease Models, Animal; Geniculate Bodies; Horseradish Peroxidase; Kainic Acid; Microscopy, Electron; Nerve Degeneration; Retina; Visual Pathways	1991
Diffusion-weighted imaging of kainic acid lesions in the rat brain. Magnetic resonance in medicine, 1991, Volume: 20, Issue:1 Topics: Amygdala; Animals; Brain; Corpus Callosum; Corpus Striatum; Diffusion; Kainic Acid; Magnetic Resonance Spectroscopy; Male; Nerve Degeneration; Putamen; Rats; Rats, Inbred Strains	1991
Neural grafts and pharmacological intervention in a model of Huntington's disease. Brain research bulletin, 1990, Volume: 25, Issue:3 Topics: Acetylcholinesterase; Amphetamine; Animals; Brain Tissue Transplantation; Catalepsy; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Electron Transport Complex IV; Female; Fetal Tissue Transplantation; Huntington Disease; Immunohistochemistry; Kainic Acid; Motor Activity; Nerve Degeneration; Pregnancy; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains	1990
Cortical neurons containing somatostatin- or parvalbumin-like immunoreactivity are atypically vulnerable to excitotoxic injury in vitro. Neurology, 1990, Volume: 40, Issue:8 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebral Cortex; Fetus; Ibotenic Acid; Kainic Acid; L-Lactate Dehydrogenase; Mice; Muscle Proteins; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Oxazoles; Parvalbumins; Somatostatin	1990
Idebenone attenuates neuronal degeneration induced by intrastriatal injection of excitotoxins. Experimental neurology, 1990, Volume: 108, Issue:1 Topics: Animals; Apomorphine; Benzoquinones; Choline O-Acetyltransferase; Corpus Striatum; Glutamate Decarboxylase; Histocytochemistry; Kainic Acid; Kinetics; Male; Motor Activity; NADPH Dehydrogenase; Nerve Degeneration; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quinones; Quisqualic Acid; Rats; Rats, Inbred Strains; Ubiquinone	1990
Thalamic retrograde degeneration following cortical injury: an excitotoxic process? Neuroscience, 1990, Volume: 35, Issue:3 Topics: Animals; Cerebral Cortex; Electron Transport Complex IV; Female; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Histocytochemistry; Kainic Acid; Mice; Mice, Inbred BALB C; Models, Neurological; Nerve Degeneration; Retrograde Degeneration; Thalamus	1990
The quantification of brain lesions with an omega 3 site ligand: a critical analysis of animal models of cerebral ischaemia and neurodegeneration. Brain research, 1990, Jul-09, Volume: 522, Issue:2 Topics: Affinity Labels; Aging; Animals; Autoradiography; Brain; Brain Ischemia; Disease Models, Animal; Isoquinolines; Kainic Acid; Male; Mice; Nerve Degeneration; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, GABA-A	1990
Transneuronal degeneration in the midbrain central gray following chemical lesions in the ventromedial nucleus: a qualitative and quantitative analysis. Neuroscience, 1990, Volume: 38, Issue:2 Topics: Animals; Cerebral Cortex; Female; Kainic Acid; Mesencephalon; N-Methylaspartate; Nerve Degeneration; Neurons; Parietal Lobe; Periaqueductal Gray; Rats; Rats, Inbred Strains; Synapses; Ventromedial Hypothalamic Nucleus	1990
Kainic acid on neostriatal neurons intracellularly recorded in vitro: electrophysiological evidence for differential neuronal sensitivity. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1990, Volume: 10, Issue:12 Topics: Action Potentials; Animals; Cell Membrane; Corpus Striatum; Dose-Response Relationship, Drug; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Male; Membrane Potentials; N-Methylaspartate; Nerve Degeneration; Neural Conduction; Neurons; Quisqualic Acid; Rats; Rats, Inbred Strains	1990
Excitotoxin-induced degeneration of rat vagal afferent neurons. Neuroscience, 1990, Volume: 34, Issue:2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Ibotenic Acid; Kainic Acid; Nerve Degeneration; Neurons, Afferent; Nodose Ganglion; Pressoreceptors; Rats; Rats, Inbred Strains; Vagus Nerve	1990
Kainic acid-induced terminal degeneration in the dorsal lateral geniculate of tree shrew. Brain research, 1987, Jul-21, Volume: 416, Issue:1 Topics: Animals; Geniculate Bodies; Horseradish Peroxidase; Kainic Acid; Nerve Degeneration; Nerve Endings; Retinal Ganglion Cells; Tupaiidae; Visual Pathways; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; Wheat Germ Agglutinins	1987
Quinolinic and kainic acids can enhance calcitonin gene-related peptide-like immunoreactivity in striatal neurons with substance P-like immunoreactivity. Brain research, 1987, Aug-25, Volume: 418, Issue:2 Topics: Animals; Calcitonin Gene-Related Peptide; Cats; Caudate Nucleus; Corpus Striatum; Female; Kainic Acid; Male; Nerve Degeneration; Neuropeptides; Puromycin; Pyridines; Quinolinic Acid; Quinolinic Acids; Substance P	1987
An appraisal of some lesioning methods applied to the posterior hypothalamus in rats. Brain, behavior and evolution, 1989, Volume: 34, Issue:3 Topics: Animals; Behavior, Animal; Brain Mapping; Electrocoagulation; Hypothalamic Area, Lateral; Hypothalamus; Hypothalamus, Posterior; Kainic Acid; Male; Motor Activity; Nerve Degeneration; Neural Pathways; Neurons; Rats; Rats, Inbred Strains; Stereotyped Behavior	1989
Translocation of zinc may contribute to seizure-induced death of neurons. Brain research, 1989, Feb-20, Volume: 480, Issue:1-2 Topics: Amygdala; Animals; Cell Survival; Cerebellum; Hippocampus; In Vitro Techniques; Kainic Acid; Nerve Degeneration; Quinolines; Rats; Seizures; Sulfonamides; Toluene; Zinc	1989
Kainic acid induces early and delayed degenerative neuronal changes in rat spinal cord. Neuroscience letters, 1989, Oct-09, Volume: 104, Issue:3 Topics: Animals; Injections, Spinal; Kainic Acid; Male; Microscopy, Electron; Nerve Degeneration; Neurotoxins; Rats; Rats, Inbred Strains; Spinal Cord	1989
Reorganization of the projection from the sensory cortex to the motor cortex following elimination of the thalamic projection to the motor cortex in cats; Golgi, electron microscope and degeneration study. Brain research, 1987, Dec-22, Volume: 437, Issue:1 Topics: Animals; Cats; Female; Golgi Apparatus; Kainic Acid; Male; Microscopy, Electron; Motor Cortex; Nerve Degeneration; Neurons; Somatosensory Cortex; Synaptic Transmission; Thalamic Nuclei	1987
Glutamate neurotoxicity in cortical cell culture. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1987, Volume: 7, Issue:2 Topics: Animals; Cell Count; Cells, Cultured; Cerebral Cortex; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Histocytochemistry; Immunoenzyme Techniques; Kainic Acid; Membrane Potentials; Mice; Nerve Degeneration	1987
AMPA is a powerful neurotoxin in the chicken retina. Neuroscience letters, 1987, Aug-31, Volume: 79, Issue:3 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chickens; Choline O-Acetyltransferase; Dose-Response Relationship, Drug; Ibotenic Acid; Injections; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Oxadiazoles; Oxazoles; Quisqualic Acid; Retina; Retinal Ganglion Cells; Vitreous Body	1987
Peripheral type benzodiazepine binding sites are a sensitive indirect index of neuronal damage. Brain research, 1987, Sep-22, Volume: 421, Issue:1-2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding Sites; Choline O-Acetyltransferase; Corpus Striatum; Glutamate Decarboxylase; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A	1987
Evidence for reactive synaptogenesis in the ventrolateral thalamus and red nucleus of the rat: changes in high affinity glutamate uptake and numbers of corticofugal fiber terminals. Experimental brain research, 1987, Volume: 69, Issue:1 Topics: Animals; Cerebellar Nuclei; Cerebral Cortex; Cerebral Decortication; Glutamates; Glutamic Acid; Kainic Acid; Male; Nerve Degeneration; Neuronal Plasticity; Rats; Rats, Inbred Strains; Red Nucleus; Thalamic Nuclei	1987
Neuroprotective effects of MK-801 in vivo: selectivity and evidence for delayed degeneration mediated by NMDA receptor activation. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1988, Volume: 8, Issue:12 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Aspartic Acid; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Ibotenic Acid; Isoflurane; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Piperazines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors	1988
Experimental striatal degeneration induced by kainic acid administration: relevance to morphological changes in Huntington's disease. The Japanese journal of psychiatry and neurology, 1986, Volume: 40, Issue:1 Topics: Animals; Corpus Striatum; Disease Models, Animal; Huntington Disease; Kainic Acid; Male; Microinjections; Microscopy, Electron; Nerve Degeneration; Rats; Rats, Inbred Strains; Stereotaxic Techniques	1986
ATP as a marker of excitotoxin-induced nerve cell death in vivo. Journal of neural transmission, 1987, Volume: 70, Issue:3-4 Topics: Adenosine Triphosphate; Animals; Cell Survival; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Neurotoxins; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains	1987
Excitatory amino acid antagonists as novel anticonvulsants. Advances in experimental medicine and biology, 1986, Volume: 203 Topics: Amino Acids, Dicarboxylic; Animals; Anticonvulsants; Aspartic Acid; Epilepsy; Glutamates; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Nervous System Diseases; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Structure-Activity Relationship	1986
Imaging of the degeneration of neurons and their processes in rat or cat brain by 45CaCl2 autoradiography or 55CoCl2 positron emission tomography. Journal of neurochemistry, 1988, Volume: 50, Issue:6 Topics: Animals; Autoradiography; Brain; Brain Diseases; Calcium; Calcium Chloride; Calcium Radioisotopes; Cats; Cobalt; Cobalt Radioisotopes; Corpus Striatum; Frontal Lobe; Hippocampus; Hydroxydopamines; Kainic Acid; Male; Nerve Degeneration; Neurons; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra; Tomography, Emission-Computed	1988
Protective effects of mossy fiber lesions against kainic acid-induced seizures and neuronal degeneration. Neuroscience, 1988, Volume: 26, Issue:3 Topics: Animals; Colchicine; Electroencephalography; Functional Laterality; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Nerve Degeneration; Rats; Rats, Inbred Strains; Reaction Time; Seizures	1988
Systemic administration of MK-801 prevents N-methyl-D-aspartate-induced neuronal degeneration in rat brain. Neuroscience letters, 1987, May-19, Volume: 76, Issue:3 Topics: Animals; Aspartic Acid; Choline O-Acetyltransferase; Corpus Striatum; Dibenzocycloheptenes; Dizocilpine Maleate; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Rats; Rats, Inbred Strains	1987
On the relation between seizures and brain lesions after intracerebroventricular kainic acid. Neuroscience letters, 1988, Jan-11, Volume: 84, Issue:1 Topics: Animals; Brain; Electroencephalography; Injections, Intraventricular; Kainic Acid; Limbic System; Male; Nerve Degeneration; Neurons; Rats; Rats, Inbred Strains; Seizures	1988
Neuronal organization of fetal striatal grafts in kainate- and sham-lesioned rat caudate nucleus: light- and electron-microscopic observations. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1988, Volume: 8, Issue:4 Topics: Animals; Caudate Nucleus; Corpus Striatum; Kainic Acid; Microscopy, Electron; Nerve Degeneration; Neurons; Rats; Rats, Inbred Strains	1988
Structural alteration and possible growth of afferents after kainate lesion in the adult rat thalamus. The Journal of comparative neurology, 1987, Apr-08, Volume: 258, Issue:2 Topics: Animals; Kainic Acid; Male; Nerve Degeneration; Neurons, Afferent; Rats; Rats, Inbred Strains; Thalamus	1987
Cellular degeneration and synaptogenesis in the developing retina of the rat. The Journal of comparative neurology, 1987, Sep-22, Volume: 263, Issue:4 Topics: Animals; Cell Survival; Injections; Kainic Acid; Nerve Degeneration; Neurons; Rats; Rats, Inbred Strains; Retina; Retinal Ganglion Cells; Synapses	1987
Ultrastructural evaluation of the damage of postsynaptic elements after kainic acid injection into the rat neostriatum. Journal of neuroscience research, 1986, Volume: 15, Issue:3 Topics: Animals; Corpus Striatum; Dendrites; Injections; Kainic Acid; Microscopy, Electron; Nerve Degeneration; Rats; Rats, Inbred Strains; Synapses; Time Factors	1986
Role of target tissue in regulating the development of retinal ganglion cells in the albino rat: effects of kainate lesions in the superior colliculus. The Journal of comparative neurology, 1986, Sep-08, Volume: 251, Issue:2 Topics: Aging; Animals; Cell Count; Horseradish Peroxidase; Ibotenic Acid; Kainic Acid; Microinjections; Nerve Crush; Nerve Degeneration; Neurotoxins; Rats; Rats, Inbred Strains; Retina; Retinal Ganglion Cells; Superior Colliculi; Time Factors; Visual Pathways	1986
Kainic acid seizures and neuronal cell death: insights from studies of selective lesions and drugs. Advances in experimental medicine and biology, 1986, Volume: 203 Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Convulsants; Hippocampus; Kainic Acid; Limbic System; Male; Nerve Degeneration; Neural Inhibition; Neural Pathways; Phenobarbital; Rats; Seizures; Time Factors	1986
Differential effects of kainic-acid-induced hippocampal lesions on the acquisition of the jump-box avoidance task in mice. Journal of neuroscience research, 1986, Volume: 15, Issue:2 Topics: Animals; Avoidance Learning; Behavior, Animal; Cerebral Cortex; Field Dependence-Independence; Hippocampus; Kainic Acid; Mice; Mice, Inbred Strains; Microinjections; Nerve Degeneration; Sodium Chloride	1986