Page last updated: 2024-08-21

kainic acid and Necrosis

kainic acid has been researched along with Necrosis in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199010 (21.74)18.7374
1990's12 (26.09)18.2507
2000's20 (43.48)29.6817
2010's3 (6.52)24.3611
2020's1 (2.17)2.80

Authors

AuthorsStudies
Gordon, RY; Khutsian, SS; Kitchigina, VF; Mikheeva, IB; Shubina, LV1
Anastassov, I; Chappell, RL; Ripps, H1
Chang, SJ; Tsai, HL1
Antonov, SM; Dvoretskova, EA; Evstratova, AA; Mironova, EV2
Brunet, N; Calderó, J; Ciutat, D; Esquerda, JE; Hereu, M1
Jantas, D; Jaworska-Feil, L; Lason, W; Lipkowski, AW1
Bikashvili, TZ; Chkhikvishvili, TsG; Kotariya, NT; Zhvaniya, MG1
Giffard, RG; Glassford, A; Lee, JE; Xu, L1
Roy, M; Sapolsky, RM1
Leuchtmann, EA; McDonald, JW; Qu, Y; Ratner, AE; Vijitruth, R1
Gale, K; Kondratyev, A1
Aronoff, R; Maricq, AV; Mellem, JE; Seeburg, PH; Sprengel, R1
Bowers, DE; Rieke, GK1
Balázs, R; Lucassen, PJ; van Lookeren Campagne, M; Vermeulen, JP1
Bennett, SA; Roberts, DC; Staines, WA; Stevenson, B1
Chen, J; Graham, SH; Marsh, T; Zhang, JS1
Freund, TF; Magloczky, Z1
Alberch, J; Ferrer, I; Macaya, A; Martin, F; Pérez-Navarro, E; Planas, AM; Reiriz, J; Serrano, T1
Kanazawa, I; Kwak, S; Nishiyama, K; Takekoshi, S; Watanabe, K1
Martin, LJ; Portera-Cailliau, C; Price, DL1
Alcantara, F; Kirchgessner, AL; Liu, MT1
Gwag, BJ; Joe, E; Kim, EY; Kim, YH; Koh, JY; Sohn, S1
Coyle, JT; Leski, ML; Valentine, SL1
Cai, B; Fujikawa, DG; Shinmei, SS2
Ajilore, O; Bliss, T; Sapolsky, R; Yusim, A1
Fujikawa, DG; Itabashi, HH; Shinmei, SS; Wu, A1
Balzer, J; Dixon, CE; Fellows, W; Kondziolka, D; Lunsford, LD; Maesawa, S1
Asrari, M; Lobner, D1
Avanzini, G; Ientile, R; Macaione, V; Oteri, G; Pedale, S; Pisani, F; Torre, V1
Baille, V; Bockaert, J; Djebaïli, M; Lerner-Natoli, M; Montpied, P; Pascale, M; Rondouin, G1
Ientile, R; Macaione, S; Macaione, V; Pedale, S; Teletta, M; Torre, V1
Cadusseau, J; Grannec, G; Jamin, N; Junier, MP1
Ferrer, I; Puig, B1
Boyko, WJ; Galabru, CK; McGeer, EG; McGeer, PL1
Ben-Ari, Y; Lagowska, Y; Le Gal La Salle, G; Naquet, R; Ottersen, OP; Tremblay, E1
Carpenter, S; Cashman, NR; Evans, AC; Gendron, D; Gjedde, A; Teitelbaum, JS; Zatorre, RJ1
Cooley, RK; Vanderwolf, CH1
Acuff, CG; Clower, BR; Rockhold, RW1
Labruyere, J; Olney, JW; Price, MT; Samson, L1
Garthwaite, G; Garthwaite, J1
Nelson, SR; Olson, JP1
Ruth, RE1
Baran, H; Hornykiewicz, O; Kitz, K; Lassmann, H; Petsche, U; Seitelberger, F; Sperk, G1
Baran, H; Hornykiewicz, O; Lassmann, H; Seitelberger, F; Sperk, G1

Other Studies

46 other study(ies) available for kainic acid and Necrosis

ArticleYear
Kainate-Induced Degeneration of Hippocampal Neurons. Protective Effect of Activation of the Endocannabinoid System.
    Bulletin of experimental biology and medicine, 2021, Volume: 171, Issue:3

    Topics: Animals; Arachidonic Acids; Autophagosomes; Benzamides; CA3 Region, Hippocampal; Carbamates; Dentate Gyrus; Endocannabinoids; Endoplasmic Reticulum; Excitatory Amino Acid Agonists; Golgi Apparatus; Kainic Acid; Lysosomes; Male; Microscopy, Electron; Necrosis; Nerve Degeneration; Polyunsaturated Alkamides; Pyramidal Cells; Rats; Rats, Wistar; Status Epilepticus

2021
Cytoprotection by endogenous zinc in the vertebrate retina.
    Journal of neurochemistry, 2014, Volume: 129, Issue:2

    Topics: Animals; Cell Survival; Chelating Agents; Dark Adaptation; Data Interpretation, Statistical; Excitatory Amino Acid Agonists; Eye; Glutamic Acid; Histidine; Kainic Acid; Necrosis; Photoreceptor Cells, Vertebrate; Retina; Skates, Fish; Zinc

2014
Key proteins of activating cell death can be predicted through a kainic acid-induced excitotoxic stress.
    BioMed research international, 2015, Volume: 2015

    Topics: Animals; Apoptosis; Biomarkers; Cell Death; Epilepsy; Kainic Acid; Necrosis; Neurons; Proteome; Proteomics; Rats; Rats, Sprague-Dawley; Seizures; Stress, Physiological

2015
[Apoptosis and its receptor selective pathways during neurotoxic action of glutamate].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2008, Volume: 94, Issue:4

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Active Transport, Cell Nucleus; Animals; Apoptosis; Apoptosis Inducing Factor; Caspase 3; Cell Nucleus; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; N-Methylaspartate; Necrosis; Neurons; Rats; Rats, Wistar; Receptors, Glutamate; Tumor Suppressor Protein p53

2008
Apoptosis and the receptor specificity of its mechanisms during the neurotoxic action of glutamate.
    Neuroscience and behavioral physiology, 2009, Volume: 39, Issue:4

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Active Transport, Cell Nucleus; Animals; Apoptosis; Apoptosis Inducing Factor; Caspase 3; Cell Nucleus; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; N-Methylaspartate; Necrosis; Neurons; Rats; Rats, Wistar; Receptors, Glutamate; Tumor Suppressor Protein p53

2009
Development of microglia in the chick embryo spinal cord: implications in the regulation of motoneuronal survival and death.
    Journal of neuroscience research, 2009, Aug-15, Volume: 87, Issue:11

    Topics: Animals; Apoptosis; Axotomy; Bungarotoxins; Cell Count; Cell Death; Cell Survival; Chick Embryo; In Vitro Techniques; Kainic Acid; Lipopolysaccharides; Macrophage Activation; Macrophages; Microglia; Motor Neurons; Necrosis; Neurotoxins; Phagocytosis; Spinal Cord; Time Factors

2009
Effects of TRH and its analogues on primary cortical neuronal cell damage induced by various excitotoxic, necrotic and apoptotic agents.
    Neuropeptides, 2009, Volume: 43, Issue:5

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Kainic Acid; Mice; Mitogen-Activated Protein Kinases; N-Methylaspartate; Necrosis; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Pregnancy; Proto-Oncogene Proteins c-akt; Quisqualic Acid; Staurosporine; Thyrotropin-Releasing Hormone

2009
Ultrastructure of hippocampal field CA1 in rats after status epilepticus induced by systemic administration of kainic acid.
    Neuroscience and behavioral physiology, 2010, Volume: 40, Issue:2

    Topics: Animals; CA1 Region, Hippocampal; Interneurons; Kainic Acid; Male; Microscopy, Electron; Mitochondria; Necrosis; Neurons; Neuropil; Rats; Status Epilepticus; Synapses; Time Factors

2010
Caspase inhibitors reduce the apoptotic but not necrotic component of kainate injury in primary murine cortical neuronal cultures.
    Neurological research, 2002, Volume: 24, Issue:8

    Topics: Animals; Apoptosis; Brain Ischemia; Caspase Inhibitors; Caspases; Cell Nucleus; Cells, Cultured; Cerebral Cortex; Down-Regulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Fetus; Kainic Acid; Mice; Necrosis; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins

2002
The neuroprotective effects of virally-derived caspase inhibitors p35 and crmA following a necrotic insult.
    Neurobiology of disease, 2003, Volume: 14, Issue:1

    Topics: Animals; Caspase 1; Caspase 3; Caspase Inhibitors; Caspases; Cells, Cultured; Chlorocebus aethiops; Cysteine Proteinase Inhibitors; Enzyme Activation; Genetic Vectors; Kainic Acid; Membrane Potentials; Necrosis; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Serpins; Simplexvirus; Vero Cells; Viral Proteins

2003
AMPA receptors are the major mediators of excitotoxic death in mature oligodendrocytes.
    Neurobiology of disease, 2003, Volume: 14, Issue:3

    Topics: Animals; Apoptosis; Astrocytes; Biomarkers; Caspases; Cell Death; Cells, Cultured; Coculture Techniques; Drug Resistance; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; Necrosis; Nerve Fibers, Myelinated; Nerve Growth Factors; Neurotoxins; Oligodendroglia; Receptors, AMPA; Receptors, Kainic Acid

2003
Latency to onset of status epilepticus determines molecular mechanisms of seizure-induced cell death.
    Brain research. Molecular brain research, 2004, Feb-05, Volume: 121, Issue:1-2

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Boron Compounds; Calpain; Caspase 3; Caspases; Deoxyribonucleases; Disease Models, Animal; DNA Fragmentation; Kainic Acid; Male; Necrosis; Nerve Degeneration; Proteins; Rats; Rats, Sprague-Dawley; Seizures; Spectrin; Status Epilepticus; Time

2004
Neuronal toxicity in Caenorhabditis elegans from an editing site mutant in glutamate receptor channels.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Sep-15, Volume: 24, Issue:37

    Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Animals, Genetically Modified; Arginine; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcium; Calcium Channels; Calreticulin; Congenital Abnormalities; Endoplasmic Reticulum; Genotype; Glutamine; Ion Transport; Kainic Acid; Mammals; Mice; Molecular Sequence Data; Necrosis; Nerve Degeneration; Neurons; Phenotype; Receptor Cross-Talk; Receptors, AMPA; Receptors, Glutamate; RNA Editing; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship; Synaptic Transmission; Touch; Vesicular Glutamate Transport Proteins

2004
Necrotizing effects of kainic acid on neurons in the pigeon brain: histological observations.
    Brain research, 1981, May-18, Volume: 212, Issue:2

    Topics: Animals; Brain; Cerebellum; Columbidae; Corpus Striatum; Diencephalon; Dominance, Cerebral; Kainic Acid; Mesencephalon; Necrosis; Neurons; Pyrrolidines; Telencephalon

1981
NMDA and kainate induce internucleosomal DNA cleavage associated with both apoptotic and necrotic cell death in the neonatal rat brain.
    The European journal of neuroscience, 1995, Jul-01, Volume: 7, Issue:7

    Topics: Animals; Animals, Newborn; Apoptosis; Brain; Dizocilpine Maleate; DNA Damage; Electrophoresis, Agar Gel; Genetic Techniques; Kainic Acid; Microscopy, Electron; N-Methylaspartate; Necrosis; Neuroprotective Agents; Nucleosomes; Rats; Time Factors

1995
Periodic acid-Schiff (PAS)-positive deposits in brain following kainic acid-induced seizures: relationships to fos induction, neuronal necrosis, reactive gliosis, and blood-brain barrier breakdown.
    Acta neuropathologica, 1995, Volume: 89, Issue:2

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Mapping; Epilepsy; Extracellular Matrix; Gliosis; Immunohistochemistry; Kainic Acid; Male; Necrosis; Nerve Degeneration; Periodic Acid-Schiff Reaction; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Status Epilepticus

1995
Expression of cyclo-oxygenase 2 in rat brain following kainate treatment.
    Neuroreport, 1995, Jan-26, Volume: 6, Issue:2

    Topics: Animals; Base Sequence; Brain; Electric Stimulation; In Situ Hybridization; Isoenzymes; Kainic Acid; Male; Molecular Sequence Data; Necrosis; Neurons; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley

1995
Selective neuronal death in the contralateral hippocampus following unilateral kainate injections into the CA3 subfield.
    Neuroscience, 1993, Volume: 56, Issue:2

    Topics: Anesthetics; Animals; Biomarkers; Calbindin 2; Cell Death; Chloral Hydrate; Disease Models, Animal; Dominance, Cerebral; Dose-Response Relationship, Drug; Drug Combinations; Epilepsy, Temporal Lobe; Ether; Hippocampus; Injections; Injections, Intraperitoneal; Kainic Acid; Magnesium Sulfate; Male; Necrosis; Nerve Degeneration; Nerve Tissue Proteins; Neural Pathways; Neurons; Pentobarbital; Pyramidal Cells; Rats; Rats, Wistar; S100 Calcium Binding Protein G; Seizures

1993
Both apoptosis and necrosis occur following intrastriatal administration of excitotoxins.
    Acta neuropathologica, 1995, Volume: 90, Issue:5

    Topics: Animals; Apoptosis; Cell Death; Corpus Striatum; Immunohistochemistry; Kainic Acid; Male; Necrosis; Neurotoxins; Quinolinic Acid; Rats; Rats, Sprague-Dawley

1995
In situ nick end-labeling detects necrosis of hippocampal pyramidal cells induced by kainic acid.
    Neuroscience letters, 1996, Jul-12, Volume: 212, Issue:2

    Topics: Animals; Apoptosis; Hippocampus; Kainic Acid; Male; Microscopy, Electron; Necrosis; Pyramidal Cells; Rats; Rats, Wistar

1996
Non-NMDA and NMDA receptor-mediated excitotoxic neuronal deaths in adult brain are morphologically distinct: further evidence for an apoptosis-necrosis continuum.
    The Journal of comparative neurology, 1997, Feb-03, Volume: 378, Issue:1

    Topics: Animals; Apoptosis; Brain; Cell Death; Dizocilpine Maleate; Kainic Acid; Male; Necrosis; Nerve Degeneration; Neurons; Neurotoxins; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate

1997
Excitotoxicity in the enteric nervous system.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Nov-15, Volume: 17, Issue:22

    Topics: Animals; Antibody Specificity; Apoptosis; Cells, Cultured; Enteric Nervous System; Excitatory Amino Acid Agonists; Ganglia; Glutamic Acid; Guinea Pigs; Kainic Acid; Male; Membrane Potentials; Mitochondria; N-Methylaspartate; Necrosis; Neurites; Neurons; Neurotoxins; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate

1997
Zn2+ entry produces oxidative neuronal necrosis in cortical cell cultures.
    The European journal of neuroscience, 1999, Volume: 11, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Chloromethyl Ketones; Animals; Antioxidants; Apoptosis; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Chromans; Cysteine Proteinase Inhibitors; Dizocilpine Maleate; Dopamine Agonists; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Free Radicals; Hypoglycemic Agents; Insulin; Kainic Acid; Lipid Peroxidation; Mice; Microscopy, Electron; Mitochondrial Swelling; Necrosis; Nerve Degeneration; Neurons; Neurotoxins; Oligopeptides; Oxidative Stress; Pregnancy; Zinc

1999
L-type voltage-gated calcium channels modulate kainic acid neurotoxicity in cerebellar granule cells.
    Brain research, 1999, May-15, Volume: 828, Issue:1-2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Apoptosis; Benzodiazepines; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Survival; Cells, Cultured; Cerebellum; Cysteine Proteinase Inhibitors; Dizocilpine Maleate; Electric Conductivity; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ion Channel Gating; Kainic Acid; Necrosis; Neurons; Nifedipine; Oligopeptides; Phosphodiesterase Inhibitors; Rats; Ryanodine; Sodium; Sucrose; Thapsigargin

1999
Kainic acid-induced seizures produce necrotic, not apoptotic, neurons with internucleosomal DNA cleavage: implications for programmed cell death mechanisms.
    Neuroscience, 2000, Volume: 98, Issue:1

    Topics: Animals; Apoptosis; Dizocilpine Maleate; DNA Fragmentation; Entorhinal Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; In Situ Nick-End Labeling; Kainic Acid; Male; Microscopy, Electron; Necrosis; Neurons; Nucleosomes; Rats; Rats, Wistar; Seizures; Status Epilepticus

2000
Glucocorticoids exacerbate insult-induced declines in metabolism in selectively vulnerable hippocampal cell fields.
    Brain research, 2000, Jul-07, Volume: 870, Issue:1-2

    Topics: Animals; Dentate Gyrus; Energy Metabolism; Excitatory Amino Acid Agonists; Glucocorticoids; Kainic Acid; Male; Necrosis; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Stress, Physiological

2000
Status epilepticus-induced neuronal loss in humans without systemic complications or epilepsy.
    Epilepsia, 2000, Volume: 41, Issue:8

    Topics: Animals; Astrocytes; Brain; Cell Death; Electroencephalography; Entorhinal Cortex; Gliosis; Hippocampus; Humans; Kainic Acid; Medical Records; Necrosis; Neocortex; Neuroglia; Neurons; Pilocarpine; Rats; Status Epilepticus

2000
Seizure-induced neuronal necrosis: implications for programmed cell death mechanisms.
    Epilepsia, 2000, Volume: 41 Suppl 6

    Topics: Animals; Apoptosis; Brain; Cell Nucleolus; Coloring Agents; DNA Damage; In Situ Nick-End Labeling; Kainic Acid; Lithium; Male; Necrosis; Neurons; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus

2000
Subnecrotic stereotactic radiosurgery controlling epilepsy produced by kainic acid injection in rats.
    Journal of neurosurgery, 2000, Volume: 93, Issue:6

    Topics: Animals; Brain Mapping; Electroencephalography; Epilepsy; Hippocampus; Kainic Acid; Male; Necrosis; Radiosurgery; Rats; Rats, Sprague-Dawley

2000
Calcitonin potentiates oxygen-glucose deprivation-induced neuronal death.
    Experimental neurology, 2001, Volume: 167, Issue:1

    Topics: Animals; Apoptosis; Calcitonin; Cell Death; Cells, Cultured; Culture Media, Serum-Free; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glucose; Hypoxia-Ischemia, Brain; Kainic Acid; Mice; N-Methylaspartate; Necrosis; Neurons; Oxygen; Receptors, AMPA; Salmon; Staurosporine

2001
Neuroprotective effects of lamotrigine and remacemide on excitotoxicity induced by glutamate agonists in isolated chick retina.
    Experimental neurology, 2001, Volume: 170, Issue:1

    Topics: Acetamides; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chick Embryo; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; L-Lactate Dehydrogenase; Lamotrigine; N-Methylaspartate; Necrosis; Neuroprotective Agents; Phenethylamines; Retina; Retinal Ganglion Cells; Triazines

2001
Molecular events involved in neuronal death induced in the mouse hippocampus by in-vivo injection of kainic acid.
    Brain research. Molecular brain research, 2001, Sep-30, Volume: 93, Issue:2

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; DNA Fragmentation; Excitatory Amino Acid Agonists; Gene Expression Regulation; Genes, p53; Hippocampus; In Situ Nick-End Labeling; Kainic Acid; Male; Mice; Mice, Knockout; Mice, Transgenic; Necrosis; Nerve Tissue Proteins; Neurons; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53

2001
Apoptosis and necrosis occurring in excitotoxic cell death in isolated chick embryo retina.
    Journal of neurochemistry, 2001, Volume: 79, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Chick Embryo; Excitatory Amino Acid Agonists; In Situ Nick-End Labeling; Kainic Acid; Kinetics; L-Lactate Dehydrogenase; N-Methylaspartate; Necrosis; Receptors, Glutamate; Retina

2001
Two temporal stages of oligodendroglial response to excitotoxic lesion in the gray matter of the adult rat brain.
    Experimental neurology, 2001, Volume: 172, Issue:1

    Topics: Animals; Apoptosis; Astrocytes; bcl-2-Associated X Protein; Brain; Cell Count; Demyelinating Diseases; Disease Progression; Female; In Situ Nick-End Labeling; Kainic Acid; Macrophages; Microglia; Myelin Sheath; Necrosis; Oligodendroglia; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Thalamus; Time Factors

2001
Caspase-3-associated apoptotic cell death in excitotoxic necrosis of the entorhinal cortex following intraperitoneal injection of kainic acid in the rat.
    Neuroscience letters, 2002, Mar-22, Volume: 321, Issue:3

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Cytochrome c Group; Entorhinal Cortex; Fas Ligand Protein; Female; Glutamic Acid; Kainic Acid; Membrane Glycoproteins; Mitochondria; Necrosis; Neurons; Neurotoxins; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Signal Transduction

2002
Thalamic injections of kainic acid produce myocardial necrosis.
    Life sciences, 1979, Jul-02, Volume: 25, Issue:1

    Topics: Animals; Hydroxydopamines; Kainic Acid; Male; Myocardium; Necrosis; Norepinephrine; Pyrrolidines; Rats; Reserpine; Thalamus

1979
Diazepam pretreatment reduces distant hippocampal damage induced by intra-amygdaloid injections of kainic acid.
    European journal of pharmacology, 1978, Dec-01, Volume: 52, Issue:3-4

    Topics: Amygdala; Animals; Convulsants; Diazepam; Hippocampus; Injections; Kainic Acid; Male; Necrosis; Pyrrolidines; Rats

1978
Neurologic sequelae of domoic acid intoxication due to the ingestion of contaminated mussels.
    The New England journal of medicine, 1990, Jun-21, Volume: 322, Issue:25

    Topics: Animals; Bivalvia; Brain; Disease Outbreaks; Electromyography; Food Contamination; Glucose; Humans; Kainic Acid; Marine Toxins; Memory Disorders; Motor Neurons; Myoclonus; Necrosis; Nervous System Diseases; Neuromuscular Diseases; Neurotransmitter Agents; Prince Edward Island; Seizures; Temporal Lobe; Tomography, Emission-Computed

1990
Phenoxybenzamine reduces mortality associated with intracerebral injections of excitatory neurotoxins.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:3

    Topics: Animals; Diencephalon; Hematuria; Injections; Kainic Acid; Kidney Cortex; Necrosis; Neurotoxins; Phenoxybenzamine; Rats; Telencephalon

1991
Excitotoxin-induced myocardial necrosis.
    European journal of pharmacology, 1989, Aug-03, Volume: 166, Issue:3

    Topics: Animals; Aspartic Acid; Blood Pressure; Cardiomyopathies; Heart Rate; Hypothalamus, Middle; Injections; Injections, Intraventricular; Kainic Acid; Male; Myocardium; N-Methylaspartate; Necrosis; Rats; Rats, Inbred Strains

1989
Calcium influx accompanies but does not cause excitotoxin-induced neuronal necrosis in retina.
    Brain research bulletin, 1985, Volume: 14, Issue:4

    Topics: Animals; Arcuate Nucleus of Hypothalamus; Aspartic Acid; Calcium; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Mice; N-Methylaspartate; Necrosis; Nicotinic Acids; Nimodipine; Pyrrolidines; Retina

1985
Neurotoxicity of excitatory amino acid receptor agonists in rat cerebellar slices: dependence on calcium concentration.
    Neuroscience letters, 1986, May-15, Volume: 66, Issue:2

    Topics: Animals; Aspartic Acid; Calcium; Cerebellum; Golgi Apparatus; Granulocytes; Kainic Acid; N-Methylaspartate; Necrosis; Neurons; Osmolar Concentration; Rats; Receptors, Amino Acid; Receptors, Cell Surface

1986
Role of early edema in the development of regional seizure-related brain damage.
    Neurochemical research, 1987, Volume: 12, Issue:6

    Topics: Animals; Brain; Brain Edema; Hippocampus; Kainic Acid; Male; Mannitol; Necrosis; Parietal Lobe; Rats; Rats, Inbred Strains; Seizures; Specific Gravity; Temporal Lobe; Thalamus

1987
Extravasated protein as a cause of limbic seizure-induced brain damage: an evaluation using kainic acid.
    Advances in experimental medicine and biology, 1986, Volume: 203

    Topics: Amygdala; Animals; Blood Proteins; Blood-Brain Barrier; Brain Mapping; Cell Survival; Female; Hippocampus; Immunoglobulin G; Kainic Acid; Necrosis; Rats; Seizures; Time Factors

1986
Ultrastructural analysis of rat brain tissue following systemic kainate administration.
    Advances in experimental medicine and biology, 1986, Volume: 203

    Topics: Animals; Astrocytes; Blood-Brain Barrier; Brain; Cerebral Cortex; Edema; Hippocampus; Horseradish Peroxidase; Kainic Acid; Necrosis; Potassium; Rats; Time Factors

1986
Kainic acid-induced seizures: dose-relationship of behavioural, neurochemical and histopathological changes.
    Brain research, 1985, Jul-15, Volume: 338, Issue:2

    Topics: Animals; Biogenic Amines; Brain; Brain Edema; Kainic Acid; Male; Necrosis; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures

1985