kainic acid has been researched along with Memory Disorders in 60 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (8.33) | 18.2507 |
| 2000's | 21 (35.00) | 29.6817 |
| 2010's | 29 (48.33) | 24.3611 |
| 2020's | 5 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Burjanadze, M; Dashniani, M; Gamkrelidze, G; Kandashvili, M; Kokaia, M; Lagani, V; Lepsveridze, E; Lordkipanidze, T; Solomonia, R; Tsverava, L | 1 |
| Babae, JF; Jogataei, MT; Mohammadi, E; Nikbakht, F; Vazifekhah, S | 1 |
| Grattan, LM; Kilmon, KA; Manahan, LM; Morris, JG; Portier, KM; Roberts, SM; Stuchal, LD | 1 |
| Moreira, JD; Müller, AP; Porciúncula, LO; Siqueira, LV; Souza, DO; Vinadé, L | 1 |
| Buchanan, RA; Consoli, DC; Dixit, S; Harrison, FE; May, JM; Nobis, WP; Tienda, AA; Wilcox, JM | 1 |
| Brazete, CS; Lukoyanov, NV; Luz, LL; Maia, GH; Soares, JI | 1 |
| Naderali, E; Nikbakht, F; Ofogh, SN; Rasoolijazi, H | 1 |
| Dong, D; Guo, SJ; Ruan, Y; Shen, DH; Wang, X; Zheng, XY; Zhu, J | 1 |
| Cai, HY; Hu, MM; Kong, LL; Qi, JS; Wang, ZJ; Wu, MN; Zhang, J | 1 |
| Gams Massi, D; Kpadonou, C; Ndiaye, M; Ouedraogo, M; Samb, A; Sow, AD; Toffa, DH | 1 |
| Chiu, KM; Lee, MY; Lin, TY; Lu, CW; Wang, MJ; Wang, SJ | 1 |
| Dong, D; Lv, YD; Qiu, X; Ruan, Y; Wu, XJ; Zheng, XY; Zhu, J | 1 |
| Al Hamda, MH; Dong, J; Xu, K; Yao, Y; Zhang, A; Zhu, M; Zhu, X | 1 |
| Cheng, W; Hu, B; Li, MQ; Lu, J; Wu, DM; Zhang, ZF; Zheng, YL | 1 |
| Brotons-Mas, JR; Cid, E; de la Prida, LM; Inostroza, M; Laurent, F | 1 |
| Arkhipov, VI; Godukhin, OV; Gordon, RY; Kapralova, MV | 1 |
| Benson, DL; Huntley, GW; Matikainen-Ankney, BA; Nikitczuk, JS; Patil, SB; Scarpa, J; Shapiro, ML | 1 |
| Chi, ZF; Duan, RS; Lin, YT; Shang, W; Sun, QJ; Wang, AH; Zhang, FX; Zheng, XY | 1 |
| Bonova, P; Burda, J; Burda, R; Danielisova, V; Gottlieb, M; Matiasova, M; Morochovic, R; Nemethova, M | 1 |
| Chen, LW; Horng, LY; Hsu, KT; Hsu, PL; Tseng, WZ; Wu, CL; Wu, RT | 1 |
| Boussadia, B; de Bock, F; Gangarossa, G; Ghosh, C; Janigro, D; Lassere, F; Marchi, N; Mselli-Lakhal, L; Pascussi, JM; Rousset, MC | 1 |
| Liang, LP; Patel, M; Pearson, JN; Roberts, LJ; Warren, E | 1 |
| Gröticke, I; Hoffmann, K; Löscher, W | 1 |
| Craig, LA; Hong, NS; Kopp, J; McDonald, RJ | 1 |
| Benke, TA; Cornejo, BJ; Mesches, MH | 1 |
| Han, PL; Jin, Y; Kim, SW; Lee, JK; Lim, CM; Park, JY; Seo, JS; Yoon, SH | 1 |
| Ashe, JH; Currás-Collazo, MC; Jebelli, AK; Qiu, S | 1 |
| Aisaki, K; Igarashi, K; Kanno, J; Kitajima, S; Matsugami, TR; Tanemura, K | 1 |
| Agostinho, PM; Cognato, GP; Cunha, RA; Hockemeyer, J; Müller, CE; Souza, DO | 1 |
| Blusztajn, JK; Glenn, MJ; Liu, YB; Mellott, TJ; Williams, CL; Wong-Goodrich, SJ | 1 |
| Adams, MA; Bechtholt-Gompf, AJ; Carlezon, WA; Cohen, BM; Ongür, D; Walther, HV | 1 |
| Burgos, JS; Pineda, A; Ramirez, C; Tercero, I | 1 |
| Aivar, P; Brotons-Mas, J; Cid, E; Gal, B; Inostroza, M; Menendez de la Prida, L; Sandi, C; Uzcategui, YG | 1 |
| Joo, SS; Kang, H; Kim, SU; Kim, TK; Kim, YB; Lee, HJ; Lee, SH; Lim, I; Matsuo, A; Park, D; Tooyama, I | 1 |
| Li, LY; Li, T; Liu, PP; Wang, Y; Zhang, HM | 1 |
| de Cabo, R; Ingram, DK; Mattson, MP; Miller, M; Qiu, G; So, KF; Spangler, EL; Wan, R; Zou, S | 1 |
| Antonucci, F; Bozzi, Y; Braida, D; Caleo, M; Clerici, M; Corradini, I; De Astis, S; Donzelli, A; Frassoni, C; Inverardi, F; Lipp, HP; Loos, M; Martucci, R; Matteoli, M; Pattini, L; Sala, M; Verderio, C; Welzl, H; Wolfer, D | 1 |
| Aguilar-Arredondo, A; Arias, C; Liquitaya-Montiel, A; Zepeda, A | 1 |
| Hattiangady, B; Shetty, AK | 1 |
| Huang, SY; Li, Z; Qiao, NN; Sun, RP; Wang, JW; Wang, YY; Yin, P | 1 |
| Choi, SS; Han, EJ; Han, KJ; Lee, HK; Lee, JK; Suh, HW | 1 |
| Chen, J; Li, C; Zhang, S | 1 |
| Shetty, AK; Zaman, V | 1 |
| Bartiromo, M; Bertolini, A; Ferrari, A; Genedani, S; Ottani, A; Renzo Botticelli, A; Saltini, S; Zaffe, D | 1 |
| Díaz-Cintra, S; Martínez, I; Morales, T; Prado-Alcalá, RA; Quirarte, GL; Quiroz, C | 1 |
| Guan, Z; Hong, J; Tang, Y; Yin, S; Zhang, W; Zhao, J | 1 |
| Arkhipov, VI; Shevchenko, NA | 1 |
| Bertchume, A; Csernansky, JG; Dong, H; Martin, MV | 1 |
| Arkhipov, VI; Kulesskaya, NA | 1 |
| Arkhipov, V; Kulesskaja, N; Lebedev, D | 1 |
| Clayton, EC; Means, LW; Peng, YG; Ramsdell, JS | 1 |
| Hirate, K; Nishikawa, T; Ohnishi, Y; Sato, T; Tanaka, K; Teramoto, T | 1 |
| Butcher, LL; Chartisathian, K; Chase, TN; Oh, JD | 1 |
| Nijjar, MS; Nijjar, SS | 1 |
| Jawad, MA; Lteif, L; Mikati, MA; Tarif, S | 1 |
| Brooke, SM; McGaugh, JL; Phillips, RG; Power, AE; Roozendaal, B; Sapolsky, RM | 1 |
| Bardgett, ME; Csernansky, JG; Yin, H | 1 |
| Bédard, L; Hockin, JC; Kosatsky, T; Perl, TM; Remis, RS; Todd, EC | 1 |
| Carpenter, S; Cashman, NR; Evans, AC; Gendron, D; Gjedde, A; Teitelbaum, JS; Zatorre, RJ | 1 |
| Zatorre, RJ | 1 |
2 review(s) available for kainic acid and Memory Disorders
| Article | Year |
|---|---|
Intrauterine environment-genome interaction and children's development (2): Brain structure impairment and behavioral disturbance induced in male mice offspring by a single intraperitoneal administration of domoic acid (DA) to their dams.
Topics: Animals; Anxiety Disorders; Brain; Brain Damage, Chronic; Demyelinating Diseases; Excitatory Amino Acid Agonists; Female; Injections, Intraperitoneal; Kainic Acid; Learning Disabilities; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Morphogenesis; Pregnancy; Prenatal Exposure Delayed Effects; Synaptic Transmission | 2009 |
Domoic acid-induced neurodegeneration resulting in memory loss is mediated by Ca2+ overload and inhibition of Ca2+ + calmodulin-stimulated adenylate cyclase in rat brain (review).
Topics: Adenylyl Cyclases; Animals; Brain; Calcium; Calmodulin; Kainic Acid; Memory; Memory Disorders; Neurodegenerative Diseases; Neurotoxins; Rats | 2000 |
58 other study(ies) available for kainic acid and Memory Disorders
| Article | Year |
|---|---|
Myo-Inositol Limits Kainic Acid-Induced Epileptogenesis in Rats.
Topics: Animals; Antinematodal Agents; Disease Models, Animal; Epilepsy; Inositol; Kainic Acid; Male; Memory Disorders; Rats; Rats, Wistar; Seizures; Vitamin B Complex | 2022 |
Evaluation the cognition-improvement effects of N-acetyl cysteine in experimental temporal lobe epilepsy in rat.
Topics: Acetylcysteine; Animals; Cognition; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; Hippocampus; Kainic Acid; Maze Learning; Memory Disorders; Rats; TOR Serine-Threonine Kinases | 2023 |
Dose-response assessment for impaired memory from chronic exposure to domoic acid among native American consumers of razor clams.
Topics: Adolescent; Adult; Aged; American Indian or Alaska Native; Animals; Bivalvia; Cohort Studies; Databases, Factual; Dose-Response Relationship, Drug; Female; Humans; Kainic Acid; Male; Memory Disorders; Middle Aged; Neuromuscular Depolarizing Agents; Shellfish Poisoning; Young Adult | 2020 |
Dietary omega-3 fatty acids prevent neonatal seizure-induced early alterations in the hippocampal glutamatergic system and memory deficits in adulthood.
Topics: Animals; Diet; Epilepsy; Fatty Acids, Omega-3; Female; Glutamic Acid; Hippocampus; Kainic Acid; Male; Memory Disorders; Pregnancy; Rats; Rats, Wistar; Seizures | 2022 |
Altered synaptic glutamate homeostasis contributes to cognitive decline in young APP/PSEN1 mice.
Topics: Amyloid beta-Protein Precursor; Animals; Cognitive Dysfunction; Electroencephalography; Epilepsy; Female; Glutamic Acid; Hippocampus; Homeostasis; Kainic Acid; Long-Term Potentiation; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Plaque, Amyloid; Presenilin-1 | 2021 |
Serotonin depletion increases seizure susceptibility and worsens neuropathological outcomes in kainate model of epilepsy.
Topics: Animals; Disease Models, Animal; Disease Susceptibility; Epilepsy; Fenclonine; Hippocampus; Kainic Acid; Male; Maze Learning; Memory Disorders; Neurons; Rats, Wistar; Seizures; Serotonin; Spatial Memory | 2017 |
The role of rosemary extract in degeneration of hippocampal neurons induced by kainic acid in the rat: A behavioral and histochemical approach.
Topics: Animals; Avoidance Learning; Disease Models, Animal; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Fluoresceins; Hippocampus; Kainic Acid; Learning Disabilities; Male; Maze Learning; Memory Disorders; Nerve Degeneration; Neurons; Neuroprotective Agents; Plant Extracts; Rats; Rats, Wistar; Rosmarinus; Time Factors | 2018 |
Kainic Acid Impairs the Memory Behavior of APP23 Mice by Increasing Brain Amyloid Load through a Tumor Necrosis Factor-α-Dependent Mechanism.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Brain; Disease Models, Animal; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Expression Regulation; Kainic Acid; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Oligopeptides; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha | 2018 |
Amyloid β protein injection into medial septum impairs hippocampal long-term potentiation and cognitive behaviors in rats.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognition; Hippocampus; Kainic Acid; Long-Term Potentiation; Maze Learning; Memory Disorders; Neuronal Plasticity; Peptide Fragments; Rats; Spatial Learning; Spatial Memory | 2018 |
Topics: Animals; Calcium; Disease Models, Animal; Epilepsy, Temporal Lobe; Female; Humans; Kainic Acid; Magnesium; Male; Memory Disorders; Mice; Mice, Inbred BALB C; Nerve Net; Prognosis; Random Allocation; Severity of Illness Index; Temporal Lobe; Treatment Outcome | 2018 |
Ropivacaine Protects against Memory Impairment and Hippocampal Damage in a Rat Neurodegeneration Model.
Topics: Animals; Apoptosis; Caspase 3; Cell Death; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Kainic Acid; Male; Memory Disorders; Mitogen-Activated Protein Kinases; Neurodegenerative Diseases; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Ropivacaine; Spatial Memory | 2018 |
Kainic acid Induces production and aggregation of amyloid β-protein and memory deficits by activating inflammasomes in NLRP3- and NF-κB-stimulated pathways.
Topics: Amyloid beta-Peptides; Animals; Inflammasomes; Kainic Acid; Memory Disorders; Mice; Microglia; Neurons; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Protein Aggregates; Reactive Oxygen Species; Signal Transduction | 2019 |
MicroRNA-23a contributes to hippocampal neuronal injuries and spatial memory impairment in an experimental model of temporal lobe epilepsy.
Topics: Animals; Antagomirs; Brain; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; Hippocampus; Kainic Acid; Male; Memory Disorders; Mice; Mice, Inbred C57BL; MicroRNAs; Neurons; Spatial Memory; Status Epilepticus; Temporal Lobe | 2019 |
Troxerutin counteracts domoic acid-induced memory deficits in mice by inhibiting CCAAT/enhancer binding protein β-mediated inflammatory response and oxidative stress.
Topics: Animals; Butadienes; CCAAT-Enhancer-Binding Protein-beta; CDC2 Protein Kinase; Gene Knockdown Techniques; Genes, ras; Hippocampus; Hydroxyethylrutoside; Inflammation; Inflammation Mediators; Kainic Acid; Male; Memory Disorders; Mice; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidases; Nitriles; Oxidative Stress; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Reactive Oxygen Species; Signal Transduction | 2013 |
Specific impairment of "what-where-when" episodic-like memory in experimental models of temporal lobe epilepsy.
Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Kainic Acid; Male; Memory; Memory Disorders; Memory, Episodic; Rats; Rats, Wistar | 2013 |
Memory disorders in rats after impairment of the dorsal hippocampal CA3 field with kainic acid.
Topics: Animals; CA3 Region, Hippocampal; Cell Death; Feeding Behavior; Kainic Acid; Male; Memory Disorders; Pyramidal Cells; Rats; Rats, Wistar | 2013 |
N-cadherin regulates molecular organization of excitatory and inhibitory synaptic circuits in adult hippocampus in vivo.
Topics: Animals; beta Catenin; Cadherins; Dendrites; Dendritic Spines; Disks Large Homolog 4 Protein; Guanylate Kinases; Hippocampus; Kainic Acid; Male; Membrane Proteins; Memory Disorders; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Neurons; Prosencephalon; Receptors, AMPA; Seizures; Spatial Memory; Synapses | 2014 |
Abnormal expression of synaptophysin, SNAP-25, and synaptotagmin 1 in the hippocampus of kainic acid-exposed rats with behavioral deficits.
Topics: Animals; Behavior, Animal; Hippocampus; Kainic Acid; Learning; Male; Memory; Memory Disorders; Rats, Wistar; Synaptophysin; Synaptosomal-Associated Protein 25; Synaptotagmin I | 2014 |
Delayed remote ischemic postconditioning protects against transient cerebral ischemia/reperfusion as well as kainate-induced injury in rats.
Topics: Animals; Brain Ischemia; CA1 Region, Hippocampal; Female; Ischemic Postconditioning; Kainic Acid; Male; Maze Learning; Memory Disorders; Rats, Wistar; Reperfusion Injury | 2014 |
Activating mitochondrial function and haemoglobin expression with EH-201, an inducer of erythropoietin in neuronal cells, reverses memory impairment.
Topics: Animals; Astrocytes; Cells, Cultured; Disease Models, Animal; Erythropoietin; Female; Glucosides; Hemoglobins; Hydrogen Peroxide; Kainic Acid; Male; Memory Disorders; Mice, Inbred C57BL; Mitochondria; Neuroprotective Agents; PC12 Cells; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Reactive Oxygen Species; Stilbenes; Succinate Dehydrogenase; Transcription Factors | 2015 |
Lack of CAR impacts neuronal function and cerebrovascular integrity in vivo.
Topics: Animals; Anxiety; Benzazepines; Brain; Calcium-Binding Proteins; Constitutive Androstane Receptor; Disease Models, Animal; Exploratory Behavior; Kainic Acid; Locomotion; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Knockout; Microfilament Proteins; Microvessels; Neuroglia; Neurons; Receptors, Cytoplasmic and Nuclear; Recognition, Psychology; Tight Junctions; Zonula Occludens Proteins | 2016 |
Scavenging of highly reactive gamma-ketoaldehydes attenuates cognitive dysfunction associated with epileptogenesis.
Topics: Aldehydes; Animals; Antioxidants; Cognitive Dysfunction; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Kainic Acid; Ketones; Male; Memory Disorders; Neuroprotective Agents; Pilocarpine; Random Allocation; Rats, Sprague-Dawley; Salicylanilides; Status Epilepticus | 2017 |
Behavioral alterations in a mouse model of temporal lobe epilepsy induced by intrahippocampal injection of kainate.
Topics: Animals; Convulsants; Dentate Gyrus; Depressive Disorder; Disease Models, Animal; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Female; Hippocampus; Kainic Acid; Learning Disabilities; Maze Learning; Memory Disorders; Mental Disorders; Mice; Mood Disorders; Nerve Degeneration; Neurocognitive Disorders; Neuropsychological Tests; Status Epilepticus | 2008 |
Reduced cholinergic status in hippocampus produces spatial memory deficits when combined with kainic acid induced seizures.
Topics: Acetylcholine; Alzheimer Disease; Animals; Antibodies, Monoclonal; Cholinergic Agents; Convulsants; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Memory Disorders; Rats; Rats, Long-Evans; Ribosome Inactivating Proteins, Type 1; Risk Factors; Saporins; Seizures; Spatial Behavior | 2008 |
A single early-life seizure impairs short-term memory but does not alter spatial learning, recognition memory, or anxiety.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anxiety; Conditioning, Classical; Disease Models, Animal; Exploratory Behavior; Fear; Female; Kainic Acid; Male; Maze Learning; Memory Disorders; Memory, Short-Term; Neuropsychological Tests; Pregnancy; Rats; Recognition, Psychology; Seizures; Space Perception | 2008 |
Fluoxetine attenuates kainic acid-induced neuronal cell death in the mouse hippocampus.
Topics: Animals; Astrocytes; Avoidance Learning; Cell Death; Cyclooxygenase 2; Dose-Response Relationship, Drug; Fluoxetine; Gliosis; Hippocampus; Interleukin-1beta; Kainic Acid; Male; Memory; Memory Disorders; Mice; Mice, Inbred BALB C; Microglia; Neurons; Neuroprotective Agents; NF-kappa B; Tumor Necrosis Factor-alpha | 2009 |
Domoic acid induces a long-lasting enhancement of CA1 field responses and impairs tetanus-induced long-term potentiation in rat hippocampal slices.
Topics: Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Electrophysiology; Enzyme Activation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Kainic Acid; Long-Term Potentiation; Male; Memory Disorders; Neuromuscular Depolarizing Agents; Neuronal Plasticity; Phosphorylation; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Tetanus | 2009 |
Caffeine and an adenosine A(2A) receptor antagonist prevent memory impairment and synaptotoxicity in adult rats triggered by a convulsive episode in early life.
Topics: Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Animals, Newborn; Caffeine; Disease Models, Animal; Disease Progression; Drug Administration Schedule; Glial Fibrillary Acidic Protein; Kainic Acid; Memory Disorders; Neurotoxicity Syndromes; Phosphodiesterase Inhibitors; Purines; Pyrimidines; Qa-SNARE Proteins; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Synapses; Synaptophysin; Synaptosomal-Associated Protein 25; Triazoles; Tritium; Xanthines | 2010 |
Water maze experience and prenatal choline supplementation differentially promote long-term hippocampal recovery from seizures in adulthood.
Topics: Animals; Choline; Female; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Hippocampus; Humans; Kainic Acid; Male; Maze Learning; Memory Disorders; Neurogenesis; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Rats; Rats, Sprague-Dawley; Retention, Psychology; Space Perception; Status Epilepticus | 2011 |
Blockade of astrocytic glutamate uptake in rats induces signs of anhedonia and impaired spatial memory.
Topics: Animals; Astrocytes; Brain; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Glutamic Acid; Kainic Acid; Male; Maze Learning; Memory Disorders; Mood Disorders; Motor Activity; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Self Administration | 2010 |
Simvastatin is the statin that most efficiently protects against kainate-induced excitotoxicity and memory impairment.
Topics: Animals; Excitatory Amino Acid Agonists; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kainic Acid; Memory Disorders; Mice; Mice, Transgenic; Neuroprotective Agents; Random Allocation; Simvastatin; Treatment Outcome | 2011 |
Hippocampal-dependent spatial memory in the water maze is preserved in an experimental model of temporal lobe epilepsy in rats.
Topics: Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Electrophysiology; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Learning; Magnetic Resonance Imaging; Male; Maze Learning; Memory Disorders; Muscarinic Agonists; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Spatial Behavior | 2011 |
Human neural stem cells overexpressing choline acetyltransferase restore cognitive function of kainic acid-induced learning and memory deficit animals.
Topics: Acetylcholine; Alzheimer Disease; Animals; Astrocytes; CA3 Region, Hippocampal; Choline O-Acetyltransferase; Cognition Disorders; Disease Models, Animal; Humans; Kainic Acid; Learning; Male; Memory Disorders; Neural Stem Cells; Neurogenesis; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation | 2012 |
Hypothermia reduces brain edema, spontaneous recurrent seizure attack, and learning memory deficits in the kainic acid treated rats.
Topics: Animals; Brain Edema; Hypothermia, Induced; Kainic Acid; Learning; Memory Disorders; Random Allocation; Rats; Rats, Sprague-Dawley; Reaction Time; Secondary Prevention; Seizures | 2011 |
Neuroprotection provided by dietary restriction in rats is further enhanced by reducing glucocortocoids.
Topics: Adrenalectomy; Animals; Brain-Derived Neurotrophic Factor; Caloric Restriction; Corticosterone; Cyclic AMP Response Element-Binding Protein; Excitatory Amino Acid Agonists; Hippocampus; HSP70 Heat-Shock Proteins; Kainic Acid; Male; Memory Disorders; Rats; Rats, Sprague-Dawley | 2012 |
Epileptiform activity and cognitive deficits in SNAP-25(+/-) mice are normalized by antiepileptic drugs.
Topics: Animals; Anticonvulsants; Association Learning; Brain; Carbamazepine; Cognition Disorders; Epilepsy; Ethosuximide; Hyperkinesis; Kainic Acid; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Nimodipine; Seizures; Synaptosomal-Associated Protein 25; Valproic Acid | 2014 |
Insulin growth factor-I promotes functional recovery after a focal lesion in the dentate gyrus.
Topics: Animals; Astrocytes; Behavior, Animal; Brain Damage, Chronic; Dendrites; Dentate Gyrus; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Fear; Glial Fibrillary Acidic Protein; Infusions, Intraventricular; Insulin-Like Growth Factor I; Kainic Acid; Male; Memory Disorders; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurogenesis; Neuronal Plasticity; Neurons; Neuropeptides; Nootropic Agents; Rats; Rats, Wistar | 2012 |
Neural stem cell grafting counteracts hippocampal injury-mediated impairments in mood, memory, and neurogenesis.
Topics: Animals; Cell Proliferation; Dentate Gyrus; Hippocampus; Intercellular Signaling Peptides and Proteins; Kainic Acid; Male; Memory Disorders; Mood Disorders; Neural Stem Cells; Neurodegenerative Diseases; Neurogenesis; Rats; Rats, Sprague-Dawley; Reelin Protein | 2012 |
Neonatal immune challenge exacerbates seizure-induced hippocampus-dependent memory impairment in adult rats.
Topics: Analysis of Variance; Animals; Animals, Newborn; Avoidance Learning; Cytokines; Disease Models, Animal; Female; Hippocampus; Kainic Acid; Lipopolysaccharides; Male; Maze Learning; Memory Disorders; Minocycline; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Seizures; Time Factors; Up-Regulation | 2013 |
Effects of MK-801 and CNQX on various neurotoxic responses induced by kainic acid in mice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Apoptosis; Blotting, Northern; Blotting, Western; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Immunoenzyme Techniques; Injections, Intraventricular; Kainic Acid; Lethal Dose 50; Male; Memory Disorders; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; Neurons; Phosphorylation; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; RNA Probes; Survival Rate | 2002 |
[Role of nitric oxide in excitotoxicity and memory impairment induced by kainic acid].
Topics: Animals; Enzyme Inhibitors; Female; Indazoles; Kainic Acid; Memory Disorders; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar | 2000 |
Fetal hippocampal CA3 cell grafts enriched with fibroblast growth factor-2 exhibit enhanced neuronal integration into the lesioned aging rat hippocampus in a kainate model of temporal lobe epilepsy.
Topics: Animals; Brain Tissue Transplantation; Bromodeoxyuridine; Cell Division; Disease Models, Animal; Epilepsy, Temporal Lobe; Fetus; Fibroblast Growth Factor 2; Graft Survival; Hippocampus; Kainic Acid; Male; Memory Disorders; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Phenotype; Rats; Rats, Inbred F344; Stem Cells | 2003 |
Effect of gamma-hydroxybutyrate in two rat models of focal cerebral damage.
Topics: Animals; Apomorphine; Brain; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Kainic Acid; Learning; Male; Memory Disorders; Motor Activity; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Rats; Rats, Wistar; Sodium Oxybate | 2003 |
Enhanced inhibitory avoidance learning prevents the memory-impairing effects of post-training hippocampal inactivation.
Topics: Animals; Avoidance Learning; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Memory; Memory Disorders; Neural Inhibition; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Reaction Time; Tetrodotoxin | 2003 |
Abnormal expression of epilepsy-related gene ERG1/NSF in the spontaneous recurrent seizure rats with spatial learning memory deficits induced by kainic acid.
Topics: Animals; Behavior, Animal; Carrier Proteins; Cell Count; Excitatory Amino Acid Agonists; Gene Expression Regulation; Immunohistochemistry; In Situ Hybridization; Kainic Acid; Male; Maze Learning; Membrane Proteins; Memory Disorders; Rats; Rats, Sprague-Dawley; Spatial Behavior; Status Epilepticus; Time Factors; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2005 |
Studies of the reproduction of long-term memory during exposure to kainic Acid.
Topics: Animals; Association Learning; Conditioning, Operant; Feeding Behavior; Habits; Hippocampus; Kainic Acid; Male; Memory Disorders; Mental Recall; Neurotoxins; Rats; Rats, Wistar | 2005 |
Low dose quetiapine reverses deficits in contextual and cued fear conditioning in rats with excitotoxin-induced hippocampal neuropathy.
Topics: Animals; Antipsychotic Agents; Conditioning, Operant; Cranial Nerve Diseases; Cues; Dibenzothiazepines; Electroshock; Excitatory Amino Acid Agonists; Fear; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Memory Disorders; Motor Activity; Neurotoxins; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Reversal Learning | 2005 |
Effect of indomethacin on kainic acid-induced memory disorders.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Conditioning, Psychological; Cyclooxygenase Inhibitors; Indomethacin; Kainic Acid; Male; Memory Disorders; Rats; Rats, Wistar | 2006 |
Behavioral perseveration and impairment of long-term memory in rats after intrahippocampal injection of kainic acid in subconvulsive dose.
Topics: Animals; Behavior, Animal; Conditioning, Operant; Electroencephalography; Excitatory Amino Acid Agonists; Extinction, Psychological; Hippocampus; Injections; Kainic Acid; Male; Memory Disorders; Rats; Rats, Wistar; Seizures | 2008 |
Working memory deficits induced by single but not repeated exposures to domoic acid.
Topics: Animals; Behavior, Animal; Brain; Drug Administration Schedule; In Vitro Techniques; Injections, Intraperitoneal; Kainic Acid; Male; Maze Learning; Memory Disorders; Mice; Random Allocation; Time Factors | 1999 |
[The ameliorating effects of a novel NC-1900 on impairments of learning/memory caused by glutamic acid].
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine Vasopressin; Avoidance Learning; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Kainic Acid; Learning Disabilities; Male; Memory Disorders; Mice; Mice, Inbred Strains; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oligopeptides; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Resorcinols | 1999 |
Overexpression of neurotrophin receptor p75 contributes to the excitotoxin-induced cholinergic neuronal death in rat basal forebrain.
Topics: Acetylcholine; Animals; Antibodies; Apoptosis; Behavior, Animal; Cell Count; Cell Death; Choline O-Acetyltransferase; Cycloheximide; DNA Fragmentation; Kainic Acid; Male; Memory Disorders; Microinjections; Neurons; Neuroprotective Agents; Neurotoxins; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptor, Nerve Growth Factor | 2000 |
Time sequence and types of memory deficits after experimental status epilepticus.
Topics: Animals; Excitatory Amino Acid Agonists; Kainic Acid; Male; Maze Learning; Memory Disorders; Rats; Rats, Sprague-Dawley; Reaction Time; Status Epilepticus; Swimming | 2001 |
Memory retrieval impairment induced by hippocampal CA3 lesions is blocked by adrenocortical suppression.
Topics: Adrenal Cortex; Animals; Corticosterone; Hippocampus; Hypothalamo-Hypophyseal System; Kainic Acid; Male; Maze Learning; Memory; Memory Disorders; Nerve Degeneration; Neural Inhibition; Neural Pathways; Pituitary-Adrenal System; Pyridines; Rats; Rats, Sprague-Dawley; Reaction Time | 2001 |
Kainic acid lesions disrupt fear-mediated memory processing.
Topics: Animals; Brain; Conditioning, Psychological; Fear; Kainic Acid; Light; Male; Memory Disorders; Rats; Rats, Sprague-Dawley | 2002 |
An outbreak of toxic encephalopathy caused by eating mussels contaminated with domoic acid.
Topics: Adult; Age Factors; Aged; Animals; Bivalvia; Brain Diseases; Canada; Disease Outbreaks; Female; Follow-Up Studies; Food Contamination; Foodborne Diseases; Gastrointestinal Diseases; Humans; Kainic Acid; Male; Marine Toxins; Memory Disorders; Middle Aged; Neurotransmitter Agents; Prince Edward Island; Sex Factors | 1990 |
Neurologic sequelae of domoic acid intoxication due to the ingestion of contaminated mussels.
Topics: Animals; Bivalvia; Brain; Disease Outbreaks; Electromyography; Food Contamination; Glucose; Humans; Kainic Acid; Marine Toxins; Memory Disorders; Motor Neurons; Myoclonus; Necrosis; Nervous System Diseases; Neuromuscular Diseases; Neurotransmitter Agents; Prince Edward Island; Seizures; Temporal Lobe; Tomography, Emission-Computed | 1990 |
Memory loss following domoic acid intoxication from ingestion of toxic mussels.
Topics: Animals; Bivalvia; Humans; Kainic Acid; Marine Toxins; Memory Disorders; Neurotoxins; Shellfish Poisoning | 1990 |