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kainic acid and Injuries, Spinal Cord

kainic acid has been researched along with Injuries, Spinal Cord in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (11.43)18.2507
2000's12 (34.29)29.6817
2010's17 (48.57)24.3611
2020's2 (5.71)2.80

Authors

AuthorsStudies
Anjum, A; Athi Kumar, RK; Cheah, YJ; Daud, MF; Idris, J; Ismail, OH; Lokanathan, Y; Mahadi, MK; Naicker, AS; Ng, MH; Tan, GC; Wong, YP; Yazid, MD1
Camiña, AE; Nishida, F; Portiansky, EL; Reggiani, PC; Sisti, MS; Zanuzzi, CN; Zappa Villar, MF1
Kaur, J; Mladinic, M; Nistri, A; Petrović, A; Tomljanović, I1
Jurcic, N; Mladinic, M; Nistri, A; Olivieri, D; Petrovic, A; Veeraraghavan, P1
Cantet, RJC; Laurella, SL; Nishida, F; Portiansky, EL; Sisti, MS; Zanuzzi, CN1
Barbeito, CG; Nishida, F; Portiansky, EL; Sisti, MS; Zanuzzi, CN1
Eltaysh, R; Farag, A; Lashen, S1
Bianchetti, E; Nistri, A; Shabbir, A1
Bianchetti, E; Cargonja, R; Mladinic, M; Nistri, A; Petrovic, A; Pilipović, K; Shabbir, A1
Kaur, J; Nistri, A; Sámano, C1
Dekanic, A; Nistri, A; Veeraraghavan, P1
Flores Gutiérrez, J; Kaur, J; Nistri, A1
Gonzalez-Inchauspe, C; Mazzone, GL; Nistri, A; Uchitel, OD; Veeraraghavan, P1
Hong, D; Tao, Y; Wu, C; Xu, R; Yang, R; Yang, Y; Yi, J1
Margaryan, G; Mladinic, M; Nistri, A; Taccola, G1
Brennan, J; Gao, Y; Gozen, O; Lepore, A; Li Jeon, N; Lorenzini, I; Poulsen, D; Robinson, MB; Rothstein, JD; Vidensky, S; Watkins, A; Won Park, J; Yang, Y1
Margaryan, G; Mattioli, C; Mladinic, M; Nistri, A2
Kuzhandaivel, A; Margaryan, G; Mazzone, GL; Mladinic, M; Nasrabady, SE; Nistri, A1
Kuzhandaivel, A; Margaryan, G; Mladinic, M; Nistri, A; Taccola, G1
Kuzhandaivel, A; Nasrabady, SE; Nistri, A1
Nasrabady, SE; Nistri, A; Sámano, C1
Deumens, R; Mazzone, GL; Taccola, G1
Guth, L; Inman, D; Steward, O1
Brené, S; Josephson, A; Olson, L; Schéele, C; Spenger, C; Trifunovski, A; Wahlestedt, C; Widenfalk, J1
Chang, SF; Hsu, CY; Lee, YH; Leu, SJ; Liaw, J; Tsai, MD; Tsai, SY; Wei, CP; Wu, CH; Yang, LY1
Choiniere, D; Teng, YD; Wrathall, JR1
Agrawal, SK; Fehlings, MG1
Burke, D; Magnuson, DS; Morassutti, DJ; Shields, CB; Trinder, TC; Zhang, YP1
He, X; Shiosaka, S; Tomizawa, K; Yamanaka, H; Yoshida, S1
Hughes, MG; McAdoo, DJ; Price, EM; Robak, G; Xu, G1
Burke, DA; Onifer, SM; Shields, CB; Zhang, YP1
Brene, S; Jubran, M; Lundströmer, K; Olson, L; Widenfalk, J1
Josephson, A; Olson, L; Spenger, C; Widenfalk, J; Widmer, HW1
Beattie, MS; Bresnahan, JC; Hermann, GE; Rogers, RC1

Other Studies

35 other study(ies) available for kainic acid and Injuries, Spinal Cord

ArticleYear
Protocol paper: kainic acid excitotoxicity-induced spinal cord injury paraplegia in Sprague-Dawley rats.
    Biological research, 2022, Dec-09, Volume: 55, Issue:1

    Topics: Animals; Disease Models, Animal; Humans; Kainic Acid; Paraplegia; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Spinal Injuries

2022
Intracerebroventricular Delivery of Human Umbilical Cord Mesenchymal Stem Cells as a Promising Therapy for Repairing the Spinal Cord Injury Induced by Kainic Acid.
    Stem cell reviews and reports, 2020, Volume: 16, Issue:1

    Topics: Animals; Cell- and Tissue-Based Therapy; Humans; Infusions, Intraventricular; Kainic Acid; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Neuroglia; Neurons; Rats; Spinal Cord; Spinal Cord Injuries; Umbilical Cord

2020
Pharmacological induction of Heat Shock Protein 70 by celastrol protects motoneurons from excitotoxicity in rat spinal cord in vitro.
    The European journal of neuroscience, 2019, Volume: 49, Issue:2

    Topics: Animals; Animals, Newborn; Cell Line, Tumor; Cell Survival; Female; HSP70 Heat-Shock Proteins; Humans; Kainic Acid; Locomotion; Male; Motor Neurons; Neuroprotective Agents; Pentacyclic Triterpenes; Rats, Wistar; Spinal Cord; Spinal Cord Injuries; Triterpenes

2019
Loss of inhibitory synapses causes locomotor network dysfunction of the rat spinal cord during prolonged maintenance in vitro.
    Brain research, 2019, 05-01, Volume: 1710

    Topics: Action Potentials; Animals; Animals, Newborn; Cell Culture Techniques; Kainic Acid; Locomotion; Motor Neurons; Periodicity; Rats; Rats, Wistar; Serotonin; Spinal Cord; Spinal Cord Injuries; Synapses; Synapsins; Synaptic Transmission; Synaptophysin

2019
Lidocaine protects neurons of the spinal cord in an excitotoxicity model.
    Neuroscience letters, 2019, 04-17, Volume: 698

    Topics: Animals; Disease Models, Animal; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Lidocaine; Male; Neurons; Neuroprotective Agents; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries

2019
Reactivity of microglia and astrocytes after an excitotoxic injury induced by kainic acid in the rat spinal cord.
    Tissue & cell, 2019, Volume: 56

    Topics: Animals; Antibodies, Anti-Idiotypic; Apoptosis; Astrocytes; Glial Fibrillary Acidic Protein; Kainic Acid; Microglia; Nerve Degeneration; Neuroglia; Neurons; Rats; Spinal Cord; Spinal Cord Injuries

2019
Histoarchitecture restoration of cerebellar sub-layers as a response to estradiol treatment following Kainic acid-induced spinal cord injury.
    Cell and tissue research, 2019, Volume: 376, Issue:3

    Topics: Animals; Astrocytes; Disease Models, Animal; Estradiol; Kainic Acid; Male; Microglia; Purkinje Cells; Rats; Rats, Wistar; Recovery of Function; Spinal Cord Injuries

2019
The volatile anesthetic methoxyflurane protects motoneurons against excitotoxicity in an in vitro model of rat spinal cord injury.
    Neuroscience, 2015, Jan-29, Volume: 285

    Topics: Action Potentials; Acute Disease; Anesthetics, Inhalation; Animals; Cell Death; Excitatory Amino Acid Agonists; Kainic Acid; Locomotion; Methoxyflurane; Motor Neurons; Neuroprotective Agents; Rats, Wistar; Reflex; Spinal Cord; Spinal Cord Injuries; Synaptic Transmission; Time Factors; Tissue Culture Techniques; Treatment Outcome

2015
Role of HSP70 in motoneuron survival after excitotoxic stress in a rat spinal cord injury model in vitro.
    The European journal of neuroscience, 2015, Volume: 42, Issue:12

    Topics: Animals; Animals, Newborn; Apoptosis Inducing Factor; Benzoquinones; Cell Death; Cell Survival; Central Nervous System Agents; Disease Models, Animal; Female; HSP70 Heat-Shock Proteins; Kainic Acid; Lactams, Macrocyclic; Locomotion; Lumbar Vertebrae; Male; Microelectrodes; Motor Neurons; Purine Nucleosides; Rats, Wistar; Spinal Cord; Spinal Cord Injuries; Thoracic Vertebrae

2015
A study of methylprednisolone neuroprotection against acute injury to the rat spinal cord in vitro.
    Neuroscience, 2016, Feb-19, Volume: 315

    Topics: Animals; Animals, Newborn; Immunohistochemistry; Kainic Acid; Lumbar Vertebrae; Membrane Potentials; Methylprednisolone; Motor Activity; N-Methylaspartate; Neural Pathways; Neuroglia; Neurons; Neuroprotective Agents; Neurotransmitter Agents; Rats, Wistar; Serotonin; Spinal Cord Injuries; White Matter

2016
A study of cannabinoid-1 receptors during the early phase of excitotoxic damage to rat spinal locomotor networks in vitro.
    Neuroscience, 2016, 10-01, Volume: 333

    Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Disease Models, Animal; Endocannabinoids; Glycerides; Kainic Acid; Locomotion; Motor Neurons; Neural Pathways; Neuroprotection; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats, Wistar; Receptor, Cannabinoid, CB1; Spinal Cord; Spinal Cord Injuries; Tissue Culture Techniques

2016
Neuroprotective effect of propofol against excitotoxic injury to locomotor networks of the rat spinal cord in vitro.
    The European journal of neuroscience, 2016, Volume: 44, Issue:7

    Topics: Animals; Disease Models, Animal; Electric Stimulation; Kainic Acid; Locomotion; Motor Neurons; Neuroprotective Agents; Periodicity; Propofol; Rats; Spinal Cord; Spinal Cord Injuries

2016
ASIC channel inhibition enhances excitotoxic neuronal death in an in vitro model of spinal cord injury.
    Neuroscience, 2017, 02-20, Volume: 343

    Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Animals; Cell Death; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Indoles; Kainic Acid; Mice; Neuroglia; Neurons; Protons; RNA, Messenger; Spinal Cord; Spinal Cord Injuries; Synaptic Transmission; Tissue Culture Techniques

2017
Domoic acid induced spinal cord lesions in adult mice: evidence for the possible molecular pathways of excitatory amino acids in spinal cord lesions.
    Neurotoxicology, 2008, Volume: 29, Issue:4

    Topics: Animals; Cell Death; Cell Line, Transformed; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Female; In Situ Nick-End Labeling; Kainic Acid; Mice; Mice, Inbred C57BL; Movement Disorders; Proteasome Endopeptidase Complex; Reactive Oxygen Species; Severity of Illness Index; Signal Transduction; Spinal Cord Injuries; Tetrazolium Salts; Thiazoles

2008
Kainate and metabolic perturbation mimicking spinal injury differentially contribute to early damage of locomotor networks in the in vitro neonatal rat spinal cord.
    Neuroscience, 2008, Aug-13, Volume: 155, Issue:2

    Topics: Action Potentials; Animals; Animals, Newborn; Cell Death; Culture Media; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; In Vitro Techniques; Kainic Acid; Locomotion; Models, Neurological; N-Methylaspartate; Nerve Net; Neurotoxins; Periodicity; Rats; Rats, Wistar; Receptors, Kainic Acid; Serotonin; Spinal Cord; Spinal Cord Injuries; Time Factors

2008
Presynaptic regulation of astroglial excitatory neurotransmitter transporter GLT1.
    Neuron, 2009, Mar-26, Volume: 61, Issue:6

    Topics: Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Cerebral Cortex; Coculture Techniques; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Embryo, Mammalian; Excitatory Amino Acid Agents; Excitatory Amino Acid Transporter 2; Green Fluorescent Proteins; Humans; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microfluidic Analytical Techniques; Mutagenesis; Nerve Degeneration; Neurons; NF-kappa B; Presynaptic Terminals; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Spinal Cord Injuries; Superoxide Dismutase; Synapses; Tetrodotoxin; Transfection; Up-Regulation

2009
Extracellular magnesium enhances the damage to locomotor networks produced by metabolic perturbation mimicking spinal injury in the neonatal rat spinal cord in vitro.
    Neuroscience, 2009, Oct-06, Volume: 163, Issue:2

    Topics: Animals; Animals, Newborn; Cell Death; Cell Hypoxia; Efferent Pathways; Excitatory Amino Acid Agonists; Extracellular Space; Hydrogen-Ion Concentration; Hypoglycemia; Kainic Acid; Locomotion; Magnesium; Nerve Fibers, Myelinated; Neurons; Oxidative Stress; Rats; Rats, Wistar; Reflex; Spinal Cord; Spinal Cord Injuries

2009
Neuroprotection of locomotor networks after experimental injury to the neonatal rat spinal cord in vitro.
    Neuroscience, 2010, Feb-03, Volume: 165, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Cell Survival; Disease Models, Animal; Drug Therapy, Combination; Efferent Pathways; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; Locomotion; Motor Neurons; Nerve Fibers, Myelinated; Neurons; Neuroprotective Agents; Posterior Horn Cells; Rats; Rats, Wistar; Spinal Cord Injuries; Time Factors

2010
Kainate-induced delayed onset of excitotoxicity with functional loss unrelated to the extent of neuronal damage in the in vitro spinal cord.
    Neuroscience, 2010, Jun-30, Volume: 168, Issue:2

    Topics: Animals; Animals, Newborn; Cell Count; Cell Survival; Electrophysiology; In Vitro Techniques; Kainic Acid; Locomotion; Motor Neurons; Neurons; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Injuries

2010
Deconstructing locomotor networks with experimental injury to define their membership.
    Annals of the New York Academy of Sciences, 2010, Volume: 1198

    Topics: Animals; Animals, Newborn; Chronic Disease; Convulsants; Excitatory Amino Acid Agonists; Glutamates; Interneurons; Kainic Acid; Locomotion; Lumbar Vertebrae; Nerve Net; Neurons; Neurotoxins; Rats; Spinal Cord Injuries; Strychnine; Wounds and Injuries

2010
Studies of locomotor network neuroprotection by the selective poly(ADP-ribose) polymerase-1 inhibitor PJ-34 against excitotoxic injury to the rat spinal cord in vitro.
    The European journal of neuroscience, 2011, Volume: 33, Issue:12

    Topics: Animals; Animals, Newborn; Cell Death; Electric Stimulation; Excitatory Amino Acid Agonists; In Vitro Techniques; Kainic Acid; Locomotion; Membrane Potentials; Neuroprotective Agents; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Spinal Cord Injuries

2011
A study of the potential neuroprotective effect of riluzole on locomotor networks of the neonatal rat spinal cord in vitro damaged by excitotoxicity.
    Neuroscience, 2012, Oct-11, Volume: 222

    Topics: Animals; Animals, Newborn; Cell Count; Cell Survival; Electric Stimulation; Electrophysiological Phenomena; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Immunohistochemistry; Kainic Acid; Locomotion; Motor Neurons; Nerve Net; Neuroprotective Agents; Rats; Rats, Wistar; Riluzole; Spinal Cord Injuries

2012
Early spread of hyperexcitability to caudal dorsal horn networks after a chemically-induced lesion of the rat spinal cord in vitro.
    Neuroscience, 2013, Jan-15, Volume: 229

    Topics: Animals; Glutamate Decarboxylase; Kainic Acid; Neuralgia; Posterior Horn Cells; Rats; Spinal Cord; Spinal Cord Injuries

2013
Genetic influences on secondary degeneration and wound healing following spinal cord injury in various strains of mice.
    The Journal of comparative neurology, 2002, Sep-23, Volume: 451, Issue:3

    Topics: Animals; Drug Resistance; Excitatory Amino Acid Agonists; Female; Kainic Acid; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nerve Degeneration; Nerve Regeneration; Neurons; Neurotoxins; Spinal Cord; Spinal Cord Injuries; Wound Healing

2002
Activity-induced and developmental downregulation of the Nogo receptor.
    Cell and tissue research, 2003, Volume: 311, Issue:3

    Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Disease Models, Animal; Down-Regulation; Ganglia, Spinal; GPI-Linked Proteins; Higher Nervous Activity; Hippocampus; Kainic Acid; Learning; Male; Motor Activity; Myelin Proteins; Neuronal Plasticity; Nogo Proteins; Nogo Receptor 1; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Peptide; RNA, Messenger; Spinal Cord; Spinal Cord Injuries

2003
Injury-induced Janus kinase/protein kinase C-dependent phosphorylation of growth-associated protein 43 and signal transducer and activator of transcription 3 for neurite growth in dorsal root ganglion.
    Journal of neuroscience research, 2007, Feb-01, Volume: 85, Issue:2

    Topics: Animals; Blotting, Western; Cells, Cultured; Cortisone; Enzyme Activation; Enzyme Inhibitors; Female; Fluorescent Antibody Technique; Ganglia, Spinal; GAP-43 Protein; Janus Kinases; Kainic Acid; Male; Nerve Regeneration; Neurites; Neurotoxins; Phosphorylation; Protein Kinase C; Rats; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord Injuries; STAT3 Transcription Factor

2007
Dose-dependent reduction of tissue loss and functional impairment after spinal cord trauma with the AMPA/kainate antagonist NBQX.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:11 Pt 1

    Topics: Animals; Dose-Response Relationship, Drug; Female; Kainic Acid; Osmolar Concentration; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spinal Cord; Spinal Cord Injuries

1994
Role of NMDA and non-NMDA ionotropic glutamate receptors in traumatic spinal cord axonal injury.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Feb-01, Volume: 17, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Cobalt; Excitatory Amino Acid Agonists; Kainic Acid; Male; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord Injuries

1997
Comparing deficits following excitotoxic and contusion injuries in the thoracic and lumbar spinal cord of the adult rat.
    Experimental neurology, 1999, Volume: 156, Issue:1

    Topics: Animals; Blood-Brain Barrier; Contusions; Electromagnetic Fields; Evoked Potentials, Motor; Excitatory Amino Acid Agonists; Kainic Acid; Locomotion; Male; Neural Pathways; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Diseases; Spinal Cord Injuries

1999
Injury induces neuropsin mRNA in the central nervous system.
    Brain research, 1999, Apr-10, Volume: 824, Issue:2

    Topics: Animals; Brain Injuries; In Situ Hybridization; Kainic Acid; Kallikreins; Mice; RNA, Messenger; Serine Endopeptidases; Spinal Cord Injuries

1999
Evidence that reversed glutamate uptake contributes significantly to glutamate release following experimental injury to the rat spinal cord.
    Brain research, 2000, May-26, Volume: 865, Issue:2

    Topics: Animals; Glutamic Acid; Kainic Acid; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries

2000
A topical mixture for preventing, abolishing, and treating autophagia and self-mutilation in laboratory rats.
    Contemporary topics in laboratory animal science, 2001, Volume: 40, Issue:2

    Topics: Administration, Topical; Animal Welfare; Animals; Female; Kainic Acid; Lumbosacral Region; Metronidazole; Pharmaceutical Preparations; Rats; Rats, Sprague-Dawley; Self Mutilation; Skin, Artificial; Spinal Cord Injuries

2001
Neurotrophic factors and receptors in the immature and adult spinal cord after mechanical injury or kainic acid.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, May-15, Volume: 21, Issue:10

    Topics: Aging; Animals; Animals, Newborn; Astrocytes; Axotomy; Disease Models, Animal; Female; Gene Expression Regulation; Kainic Acid; Meninges; Nerve Growth Factors; Rats; Rats, Sprague-Dawley; Receptors, Nerve Growth Factor; RNA, Messenger; Schwann Cells; Spinal Cord; Spinal Cord Injuries; Wounds, Nonpenetrating

2001
NOGO mRNA expression in adult and fetal human and rat nervous tissue and in weight drop injury.
    Experimental neurology, 2001, Volume: 169, Issue:2

    Topics: Adult; Animals; Animals, Newborn; Fetus; Ganglia; Ganglia, Spinal; Gene Expression Regulation; Growth Inhibitors; Humans; Kainic Acid; Motor Neurons; Myelin Proteins; Neurons; Neurons, Afferent; Nogo Proteins; Organ Specificity; Protein Isoforms; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spinal Cord; Spinal Cord Injuries; Transcription, Genetic; Weight-Bearing

2001
Tumor necrosis factor-alpha induces cFOS and strongly potentiates glutamate-mediated cell death in the rat spinal cord.
    Neurobiology of disease, 2001, Volume: 8, Issue:4

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cell Death; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Male; Microglia; Neurons; Neurotoxins; Phenotype; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Tumor Necrosis Factor-alpha

2001