Page last updated: 2024-08-21

kainic acid and Inflammation

kainic acid has been researched along with Inflammation in 69 studies

Research

Studies (69)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (1.45)	18.2507
2000's	12 (17.39)	29.6817
2010's	40 (57.97)	24.3611
2020's	16 (23.19)	2.80

Authors

Authors	Studies
Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J	1
Anilakumar, KR; Chandrasekhar, Y; Kumar, GP; Ramya, EM	1
Audinat, E; Blaquiere, M; Canet, G; deBock, F; Desrumaux, C; Garcia, V; Givalois, L; Hernandez, C; Marchi, N; Moreno-Montano, M; Planel, E; Vitalis, M; Zub, E; Zussy, C	1
Chen, C; Dong, X; Fan, J; Gong, L; He, D; Jiang, J; Jiang, P; Kuang, H; Kuang, R; Lin, D; Shen, W; Wang, X; Xia, N; Xie, Y; Zeng, L	1
Chang, A; Chang, Y; Wang, SJ	1
Audinat, E; Blaquiere, M; Canet, G; de Bock, F; Garbelli, R; Givalois, L; Klement, W; Marchi, N; Pastori, C; Reutelingsperger, C; Rossini, L; Sheikh, M; Solito, E; Zub, E	1
Deng, L; Liu, G; Lu, J; Yang, P; Zhou, N	1
Das, A; Das, S; Deller, T; Fan, W; Fu, T; Kur, IM; Momma, S; Müller-Braun, F; Prouvot, PH; Roeper, J; Stroh, A	1
Feria-Romero, I; Gallardo, JM; Guerra-Araiza, C; Guevara-Guzmán, R; Neri-Gomez, T; Orozco-Suarez, S; Rocha, L; Suárez-Santiago, JE; Vega-García, A	1
Fox, P; Koh, S; Mithal, DS; Sanchez, RM; Somogyi, JR; Vien, AC	1
Baluchnejadmojarad, T; Fahanik-Babaei, J; Mohamadi-Zarch, SM; Nazari-Serenjeh, M; Nourabadi, D; Ramazi, S; Roghani, M; Tashakori-Miyanroudi, M	1
Blain, EJ; Bonnet, CS; Gilbert, SJ; Mason, DJ; Williams, AS	1
Morales, T; Reyes-Mendoza, J	1
Khanizadeh, AM; Mojarad, TB; Nikbakht, F; Vazifehkhah, S	1
Dong, X; Fan, M; Hao, X; Huang, X; Jiang, P; Wang, X; Xie, Y; Xu, P; Zeng, L	1
Brugeaud, A; Coppola, G; Edge, ASB; Lin, HC; Petrillo, M; Seist, R; Stankovic, KM; Wu, CC; Yeh, WH	1
Feixiang, S; Guo, M; Haiyan, G; Jiahang, S; Jie, L; Shengjie, S; Sihua, Q; Xiaoying, G; Yanmei, Z; Ying, C	1
Bie, B; Chen, Y; Li, H; Li, J; Sheng, L; Wang, Z; Ye, J; You, H; Zhang, Q	1
Guan, L; Li, H; Li, S; Li, X; Li, Y; Lin, J; Shi, Y; Yang, C; Zhang, Y	1
Chen, YC; Du, TT; Jiang, Y; Liu, DF; Liu, YY; Shi, L; Wang, X; Zhang, JG; Zhang, X; Zhu, GY	1
Auladell, C; Beas-Zarate, C; Busquets, O; Camins, A; Castro-Torres, RD; Ettcheto, M; Folch, J; Verdaguer, E	1
Albertini, MC; Ambrogini, P; Bartolini, D; Betti, M; Cuppini, R; Di Palma, M; Galati, C; Galli, F; Lattanzi, D; Minelli, A; Olivieri, F; Palma, E; Ruffolo, G; Saccomanno, S; Savelli, D; Torquato, P	1
Jia, YJ; Li, TR; Lv, RJ; Ma, C; Qiu, WY; Shao, XQ; Wang, Q	1
Huang, WS; Zhu, L	1
Chen, W; He, Q; Hu, Y; Jiang, L; Man, S; Wu, L	1
Hsieh, HL; Hsieh, TY; Huang, SK; Lin, TY; Lu, CW; Wang, SJ	1
Kim, YB; Park, D; Yon, JM	1
Liu, YH; Qi, AQ; Qi, QD; Zhang, YH; Zhu, JL	1
Albertini, MC; Ambrogini, P; Bartolini, D; Betti, M; Cuppini, R; Di Palma, M; Galli, F; Lattanzi, D; Marinelli, R; Minelli, A; Torquato, P	1
Dingledine, R; Du, Y; Jiang, J; Kinjo, ER; Nguyen, HP; Yu, Y	1
Cheng, B; Cheng, Y; Fu, H; Huang, W; Li, X; Li, Y; Lu, P; Luo, H; Qi, Z; Rong, Z; Wang, X; Yao, Y; Ye, X; Zhang, YW; Zheng, H; Zheng, W	1
Adeyemi, OO; Afolayan, OO; Ajayi, AM; Ben-Azu, B; Ishola, IO; James, AB; Ojo, ES; Umukoro, S	1
Cheng, W; Hu, B; Li, MQ; Lu, J; Wu, DM; Zhang, ZF; Zheng, YL	1
Dirnagl, U; Dyrks, T; Graham, K; Harhausen, D; Khojasteh, U; Müller, J; Sudmann, V; Thiele, A; Wunder, A; Zille, M	1
Konat, GW; Michalovicz, LT	1
Hsieh, CL; Lin, YW	1
Chan, JY; Chang, AY; Chao, YM; Ho, YH; Lin, YT; Wu, CW	1
Choi, CH; Heo, RW; Kang, DH; Kim, H; Roh, GS; Yi, CO	1
Angibaud, J; Avignone, E; Lepleux, M; Nägerl, UV	1
Boussadia, B; Fontanaud, P; Hirbec, HE; Lasgouzes, T; Linck, N; Marchi, N; Peyroutou, R; Rassendren, FA; Sabilallah, M	1
Allegra, M; Bozzi, Y; Caleo, M; Cerri, C; Genovesi, S; Guglielmotti, A; Perry, VH; Pistillo, F; Püntener, U	1
Liu, J; Liu, Y; Liu, Z; Wang, F; Wang, S; Zhao, Y	1
Balzekas, I; Hernandez, J; Koh, S; White, J	1
Alikashani, A; Do Carmo, S; Najyb, O; Rassart, E	1
Baek, H; Kim, DW; Kim, HR; Kim, JJ; Kim, S; Kim, SR; Kim, Y; Kwon, OY; Lee, SJ; Lee, YH; Oh, SH; Park, JB; Shin, N; Yi, MH; Zhang, E	1
Bankstahl, JP; Bankstahl, M; Bar-Klein, G; Bascuñana, P; Brandt, C; Dalipaj, H; Friedman, A; Klee, R; Löscher, W; Töllner, K	1
Baek, H; Byun, HS; Cho, HS; Hong, J; Hur, GM; Jeon, BH; Kim, DW; Kim, HW; Lee, YR; Lim, CS; Park, JB; Shin, YS	1
Ho, WH; Lee, WT; Lin, YC; Liu, CL; Yang, MT	1
Lee, JK; Singh, AK; Singh, I; Won, JS	1
Carey, AN; Galli, RL; Ingram, DK; Joseph, JA; Lau, FC; Shukitt-Hale, B; Spangler, EL	1
Abdipranoto-Cowley, A; Croucher, D; Daniel, J; Galbraith, S; Henshall, S; Mervin, K; Park, JS; Vissel, B	1
Chiang, AY; Jolly, RA; Jordan, WH; Reams, RY; Ryan, TP; Searfoss, GH; Sharma, AK; Snyder, PW	1
Holopainen, IE; Järvelä, JT; Kukko-Lukjanov, TK; Lopez-Picon, FR; Plysjuk, A; Ruohonen, S	1
Guan, X; Lu, W; Petralia, RS; Rothstein, JD; Tao, YX; Yaster, M	1
Belan, P; Kao, SC; Kopach, O; Petralia, RS; Tao, YX; Voitenko, N	1
Ambrogini, P; Betti, M; Canonico, B; Ciuffoli, S; Colombo, E; Cuppini, R; Galli, F; Lattanzi, D; Minelli, A; Sestili, P; Viola, V	1
Baille, V; Barbier, L; Beaup, C; Carpentier, P; Depaulis, A; Dhote, F; Dorandeu, F; Heinrich, C; Peinnequin, A; Pernot, F	1
Banares, S; Hakem, R; Head, BP; Hu, Y; Huang, X; Krajewska, M; Krajewski, S; Kress, C; Kyoda, T; Leyva, R; Reed, JC; Rong, J; Salmena, L; Sze, CH; Whalen, MJ; Yang, J; You, Z	1
Dhanushkodi, A; McDonald, MP	1
Ndode-Ekane, XE; Pitkänen, A	1
Dhabhar, FS; Dinkel, K; Sapolsky, RM	1
Adamo, EB; Altavilla, D; Calabresi, P; Campo, GM; Costa, C; Esposito, M; Ientile, R; Marini, H; Marini, R; Minutoli, L; Passaniti, M; Pisani, F; Squadrito, F	1
Dreyer, J; Kuner, R; Kuner, T; Kusumawidijaja, G; Müller-Esterl, W; Oess, S; Schilling, K; Schleicher, M; Tappe, A	1
De Simoni, MG; Moshé, SL; Perego, C; Ravizza, T; Richichi, C; Rizzi, M; Velísková, J; Vezzani, A	1
Anderson, C; Behanna, HA; Koh, S; Robin, B; Somera, CA; Somera-Molina, KC; Stine, C; Van Eldik, LJ; Wainwright, MS; Watterson, DM	1
Andrianov, GN; Nozdrachev, AD; Ryzhova, IV	1
Furuta, K; Ito, S; Mabuchi, T; Maeda, M; Minami, T; Soen, M; Suzuki, M; Tatsumi, S	1
Auvin, S; Mazarati, A; Sankar, R; Shin, D	1
Bolton, SJ; Perry, VH	1

Reviews

1 review(s) available for kainic acid and Inflammation

Article	Year
Excitotoxicity, neuroinflammation and oxidant stress as molecular bases of epileptogenesis and epilepsy-derived neurodegeneration: The role of vitamin E. Biochimica et biophysica acta. Molecular basis of disease, 2019, 06-01, Volume: 1865, Issue:6 Topics: Animals; Antioxidants; Brain; Epilepsy; Humans; Inflammation; Kainic Acid; Neurodegenerative Diseases; Oxidative Stress; Vitamin E	2019

Other Studies

68 other study(ies) available for kainic acid and Inflammation

Article	Year
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. Current protocols in cytometry, 2010, Volume: Chapter 13 Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature	2010
Adaptogenic potential of ginsenosides against domoic acid-induced toxicity by regulating neuronal stress and kinate receptors: Ex vivo and in silico studies. Journal of food biochemistry, 2022, Volume: 46, Issue:5 Topics: Animals; Ginsenosides; Inflammation; Kainic Acid; Mice; Nootropic Agents; Panax; Plant Extracts; Poisons	2022
Seizure activity triggers tau hyperphosphorylation and amyloidogenic pathways. Epilepsia, 2022, Volume: 63, Issue:4 Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Inflammation; Kainic Acid; Mice; Mice, Inbred C57BL; Seizures; Status Epilepticus	2022
Captopril alleviates epilepsy and cognitive impairment by attenuation of C3-mediated inflammation and synaptic phagocytosis. Journal of neuroinflammation, 2022, Sep-14, Volume: 19, Issue:1 Topics: Animals; Captopril; Cognitive Dysfunction; Epilepsy; Inflammation; Kainic Acid; Phagocytosis; Rats; Rats, Sprague-Dawley	2022
Rutin prevents seizures in kainic acid-treated rats: evidence of glutamate levels, inflammation and neuronal loss modulation. Food & function, 2022, Oct-17, Volume: 13, Issue:20 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport Systems; Animals; Anti-Inflammatory Agents; Carbamazepine; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Hippocampus; HMGB1 Protein; Inflammation; Interleukin-10; Interleukin-1beta; Interleukin-6; Kainic Acid; N-Methylaspartate; Rats; Receptors, Interleukin-1; Rutin; Seizures; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha	2022
The GR-ANXA1 pathway is a pathological player and a candidate target in epilepsy. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:12 Topics: Animals; Annexin A1; Blood Cell Count; Brain; Corticosterone; Epilepsy; Gene Expression Regulation; Hippocampus; Humans; Inflammation; Kainic Acid; Mice; Mice, Inbred C57BL; Receptors, Glucocorticoid	2019
MicroRNA-27a-3p Downregulation Inhibits Inflammatory Response and Hippocampal Neuronal Cell Apoptosis by Upregulating Mitogen-Activated Protein Kinase 4 (MAP2K4) Expression in Epilepsy: In Vivo and In Vitro Studies. Medical science monitor : international medical journal of experimental and clinical research, 2019, Nov-11, Volume: 25 Topics: Animals; Apoptosis; Cell Survival; Disease Models, Animal; Down-Regulation; Epilepsy; Gene Expression Regulation; HEK293 Cells; Hippocampus; Humans; Inflammation; Kainic Acid; Male; MAP Kinase Kinase 4; MicroRNAs; Neurons; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Transcriptional Activation; Tumor Necrosis Factor-alpha	2019
Neuronal activity triggers uptake of hematopoietic extracellular vesicles in vivo. PLoS biology, 2020, Volume: 18, Issue:3 Topics: Animals; Blood Cells; Brain; Dopaminergic Neurons; Extracellular Vesicles; Female; Hippocampus; Inflammation; Kainic Acid; Lipopolysaccharides; Male; Mice, Transgenic; Optogenetics; Proteasome Endopeptidase Complex; Signal Transduction; Stereotaxic Techniques; Ubiquitin	2020
Magnolia officinalis Reduces Inflammation and Damage Induced by Recurrent Status Epilepticus in Immature Rats. Current pharmaceutical design, 2020, Volume: 26, Issue:12 Topics: Animals; Disease Models, Animal; Hippocampus; Inflammation; Kainic Acid; Magnolia; Rats; Rats, Sprague-Dawley; Status Epilepticus	2020
Dexamethasone after early-life seizures attenuates increased susceptibility to seizures, seizure-induced microglia activation and neuronal injury later in life. Neuroscience letters, 2020, 05-29, Volume: 728 Topics: Animals; Dexamethasone; Disease Models, Animal; Epilepsy; Hippocampus; Inflammation; Kainic Acid; Macrophage Activation; Male; Microglia; Neurons; Rats, Long-Evans; Seizures	2020
Neuroprotective and anticonvulsant effects of sinomenine in kainate rat model of temporal lobe epilepsy: Involvement of oxidative stress, inflammation and pyroptosis. Journal of chemical neuroanatomy, 2020, Volume: 108 Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Inflammation; Kainic Acid; Male; Morphinans; Neuroprotective Agents; Oxidative Stress; Pyroptosis; Rats; Reactive Oxygen Species	2020
AMPA/kainate glutamate receptor antagonists prevent posttraumatic osteoarthritis. JCI insight, 2020, 07-09, Volume: 5, Issue:13 Topics: Adolescent; Aged; Aged, 80 and over; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Inflammation; Kainic Acid; Male; Mice, Inbred C57BL; Osteoarthritis	2020
Prolactin treatment reduces kainic acid-induced gliosis in the hippocampus of ovariectomized female rats. Brain research, 2020, 11-01, Volume: 1746 Topics: Animals; Anti-Inflammatory Agents; Cytokines; Excitatory Amino Acid Agonists; Female; Gliosis; Inflammation; Kainic Acid; Neuroprotective Agents; Ovariectomy; Prolactin; Rats; Rats, Wistar	2020
The possible role of progranulin on anti-inflammatory effects of metformin in temporal lobe epilepsy. Journal of chemical neuroanatomy, 2020, Volume: 109 Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Epilepsy, Temporal Lobe; Glial Fibrillary Acidic Protein; Hippocampus; Inflammation; Kainic Acid; Metformin; Progranulins; Rats	2020
RNA sequencing analysis of cortex and hippocampus in a kainic acid rat model of temporal lobe epilepsy to identify mechanisms and therapeutic targets related to inflammation, immunity and cognition. International immunopharmacology, 2020, Volume: 87 Topics: Animals; Cerebral Cortex; Cognition; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Immunity; Inflammation; Kainic Acid; Male; Rats, Sprague-Dawley; Sequence Analysis, RNA; Transcriptome	2020
Altered expression of genes regulating inflammation and synaptogenesis during regrowth of afferent neurons to cochlear hair cells. PloS one, 2020, Volume: 15, Issue:10 Topics: Animals; Animals, Newborn; Gene Expression; Hair Cells, Auditory; Inflammation; Kainic Acid; Mice; Mice, Inbred C57BL; Models, Neurological; Nerve Regeneration; Neurogenesis; Neurons, Afferent; Spiral Ganglion; Synapses; Tissue Culture Techniques	2020
CircHivep2 contributes to microglia activation and inflammation via miR-181a-5p/SOCS2 signalling in mice with kainic acid-induced epileptic seizures. Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:22 Topics: Adipocytes; Animals; Biotinylation; Cell Line; DNA-Binding Proteins; Epilepsy; Exosomes; Gene Expression Profiling; Gene Expression Regulation; Hippocampus; In Situ Hybridization, Fluorescence; Inflammation; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Microglia; MicroRNAs; Oligonucleotide Array Sequence Analysis; RNA, Circular; RNA, Long Noncoding; Seizures; Signal Transduction; Suppressor of Cytokine Signaling Proteins	2020
Vagus nerve stimulation affects inflammatory response and anti-apoptosis reactions via regulating miR-210 in epilepsy rat model. Neuroreport, 2021, 06-09, Volume: 32, Issue:9 Topics: Animals; Apoptosis; Disease Models, Animal; Epilepsy; Hippocampus; Inflammation; Kainic Acid; Male; MicroRNAs; Rats; Rats, Sprague-Dawley; Vagus Nerve Stimulation	2021
Abnormal neuronal damage and inflammation in the hippocampus of kainic acid-induced epilepsy mice. Cell biochemistry and function, 2021, Volume: 39, Issue:6 Topics: Animals; Disease Models, Animal; Doublecortin Protein; Epilepsy; Hippocampus; Inflammation; Kainic Acid; Mice; Mice, Inbred C57BL; Neurons	2021
Anterior thalamic nuclei deep brain stimulation reduces disruption of the blood-brain barrier, albumin extravasation, inflammation and apoptosis in kainic acid-induced epileptic rats. Neurological research, 2017, Volume: 39, Issue:12 Topics: Albumins; Animals; Anterior Thalamic Nuclei; Apoptosis; Blood-Brain Barrier; Capillary Permeability; Deep Brain Stimulation; Disease Models, Animal; Epilepsy; Inflammation; Kainic Acid; Male; Random Allocation; Rats, Sprague-Dawley	2017
JNK1 inhibition by Licochalcone A leads to neuronal protection against excitotoxic insults derived of kainic acid. Neuropharmacology, 2018, 03-15, Volume: 131 Topics: Animals; Anticonvulsants; Cell Survival; Chalcones; Hippocampus; Inflammation; Kainic Acid; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 8; Neurons; Neuroprotection; Neuroprotective Agents; Oxidative Stress; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Seizures	2018
Neurobiological Correlates of Alpha-Tocopherol Antiepileptogenic Effects and MicroRNA Expression Modulation in a Rat Model of Kainate-Induced Seizures. Molecular neurobiology, 2018, Volume: 55, Issue:10 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; alpha-Tocopherol; Animals; Blood-Brain Barrier; Disease Models, Animal; Gene Expression Regulation; Inflammation; Kainic Acid; Male; MicroRNAs; Nerve Degeneration; Oocytes; Oxidative Stress; Rats, Sprague-Dawley; Receptors, GABA; Seizures; Status Epilepticus; Xenopus	2018
The role of the microRNA-146a/complement factor H/interleukin-1β-mediated inflammatory loop circuit in the perpetuate inflammation of chronic temporal lobe epilepsy. Disease models & mechanisms, 2018, 03-23, Volume: 11, Issue:3 Topics: Animals; Case-Control Studies; Cell Line; Chronic Disease; Complement Factor H; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Gene Knockdown Techniques; Hippocampus; Humans; Inflammation; Interleukin-1beta; Kainic Acid; Male; MicroRNAs; Rats, Sprague-Dawley; Up-Regulation	2018
MiR-134 expression and changes in inflammatory cytokines of rats with epileptic seizures. European review for medical and pharmacological sciences, 2018, Volume: 22, Issue:11 Topics: Animals; Brain; Cell Proliferation; Cytokines; Epilepsy; Hippocampus; Inflammation; Kainic Acid; Male; MicroRNAs; Neurons; Rats; Seizures	2018
Curcumin Reduces Neuronal Loss and Inhibits the NLRP3 Inflammasome Activation in an Epileptic Rat Model. Current neurovascular research, 2018, Volume: 15, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Cognition Disorders; Curcumin; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Agonists; Female; Hippocampus; Inflammation; Interleukin-1beta; Kainic Acid; Male; Maze Learning; Neurons; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Rats, Sprague-Dawley	2018
Echinacoside, an Active Constituent of Cistanche Herba, Exerts a Neuroprotective Effect in a Kainic Acid Rat Model by Inhibiting Inflammatory Processes and Activating the Akt/GSK3β Pathway. Biological & pharmaceutical bulletin, 2018, Nov-01, Volume: 41, Issue:11 Topics: Animals; Brain; Cistanche; Cytokines; Disease Models, Animal; Epilepsy; Glutamic Acid; Glycogen Synthase Kinase 3 beta; Glycosides; Inflammation; Kainic Acid; Male; Microglia; Neuroprotective Agents; Neurotoxicity Syndromes; Phosphorylation; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats, Sprague-Dawley; Seizures; Signal Transduction	2018
The Ethanol Fraction of White Rose Petal Extract Abrogates Excitotoxicity-Induced Neuronal Damage Nutrients, 2018, Sep-26, Volume: 10, Issue:10 Topics: Animals; Antioxidants; Brain; Cytokines; Ethanol; Flowers; Humans; Inflammation; Kainic Acid; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; Neural Stem Cells; Oxidative Stress; Phytotherapy; Plant Extracts; Rosa; Seizures	2018
Overexpressed HspB6 Underlines a Novel Inhibitory Role in Kainic Acid-Induced Epileptic Seizure in Rats by Activating the cAMP-PKA Pathway. Cellular and molecular neurobiology, 2019, Volume: 39, Issue:1 Topics: Animals; Apoptosis; Base Sequence; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Hippocampus; HSP20 Heat-Shock Proteins; Inflammation; Kainic Acid; Male; MAP Kinase Kinase Kinase 5; Neurons; Phosphorylation; Rats, Sprague-Dawley; Seizures; Signal Transduction	2019
Suppressing pro-inflammatory prostaglandin signaling attenuates excitotoxicity-associated neuronal inflammation and injury. Neuropharmacology, 2019, 05-01, Volume: 149 Topics: Animals; Blood-Brain Barrier; Brain; Brain Injuries; Cytokines; Dinoprostone; Disease Models, Animal; Gliosis; Hippocampus; Indoles; Inflammation; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Receptors, Prostaglandin E, EP2 Subtype; Seizures; Signal Transduction; Status Epilepticus	2019
Silencing MicroRNA-155 Attenuates Kainic Acid-Induced Seizure by Inhibiting Microglia Activation. Neuroimmunomodulation, 2019, Volume: 26, Issue:2 Topics: Adult; Animals; Convulsants; Epilepsy, Temporal Lobe; Female; Humans; Inflammation; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Microglia; MicroRNAs; Seizures	2019
Ameliorative influence of Cnestis ferruginea vahl ex DC (Connaraceae) root extract on kainic acid-induced temporal lobe epilepsy in mice: Role of oxidative stress and neuroinflammation. Journal of ethnopharmacology, 2019, Oct-28, Volume: 243 Topics: Animals; Anticonvulsants; Connaraceae; Cyclooxygenase 2; Epilepsy, Temporal Lobe; Hippocampus; Inflammation; Kainic Acid; Male; Medicine, African Traditional; Mice; NF-kappa B; Oxidative Stress; Plant Extracts; Plant Roots; Seizures	2019
Troxerutin counteracts domoic acid-induced memory deficits in mice by inhibiting CCAAT/enhancer binding protein β-mediated inflammatory response and oxidative stress. Journal of immunology (Baltimore, Md. : 1950), 2013, Apr-01, Volume: 190, Issue:7 Topics: Animals; Butadienes; CCAAT-Enhancer-Binding Protein-beta; CDC2 Protein Kinase; Gene Knockdown Techniques; Genes, ras; Hippocampus; Hydroxyethylrutoside; Inflammation; Inflammation Mediators; Kainic Acid; Male; Memory Disorders; Mice; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidases; Nitriles; Oxidative Stress; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Reactive Oxygen Species; Signal Transduction	2013
Specific imaging of inflammation with the 18 kDa translocator protein ligand DPA-714 in animal models of epilepsy and stroke. PloS one, 2013, Volume: 8, Issue:8 Topics: Animals; Autoradiography; Blood-Brain Barrier; Carrier Proteins; Cells, Cultured; Disease Models, Animal; Epilepsy; Fluorine Radioisotopes; Immunoenzyme Techniques; Inflammation; Kainic Acid; Macrophages; Male; Mice; Mice, Inbred C57BL; Microglia; Positron-Emission Tomography; Pyrazoles; Pyrimidines; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, GABA-A; Stroke	2013
Peripherally restricted acute phase response to a viral mimic alters hippocampal gene expression. Metabolic brain disease, 2014, Volume: 29, Issue:1 Topics: Acute-Phase Reaction; Cytokines; Disease Susceptibility; Dose-Response Relationship, Drug; Exploratory Behavior; Gene Expression Regulation; Hippocampus; Illness Behavior; Inflammation; Kainic Acid; MicroRNAs; Molecular Mimicry; Nerve Tissue Proteins; Neuroimmunomodulation; Neurotoxins; Poly I-C; Receptors, Chemokine; Receptors, Cytokine; Seizures; Synaptic Transmission; Up-Regulation	2014
Auricular electroacupuncture reduced inflammation-related epilepsy accompanied by altered TRPA1, pPKCα, pPKCε, and pERk1/2 signaling pathways in kainic acid-treated rats. Mediators of inflammation, 2014, Volume: 2014 Topics: Animals; Electroacupuncture; Epilepsy; Inflammation; Kainic Acid; Male; MAP Kinase Signaling System; Protein Kinase C-alpha; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Signal Transduction; TRPA1 Cation Channel; TRPC Cation Channels	2014
Peripheral inflammation increases seizure susceptibility via the induction of neuroinflammation and oxidative stress in the hippocampus. Journal of biomedical science, 2015, Jun-24, Volume: 22 Topics: Animals; Cyclic N-Oxides; Epilepsy, Temporal Lobe; Hippocampus; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Kainic Acid; Lipopolysaccharides; Microglia; Nitrobenzenes; Oxidative Stress; Rats; Seizures; Spin Labels; Sulfonamides; Tumor Necrosis Factor-alpha	2015
High-fat diet-induced obesity exacerbates kainic acid-induced hippocampal cell death. BMC neuroscience, 2015, Oct-30, Volume: 16 Topics: Animals; Cell Death; Diet, High-Fat; Excitatory Amino Acid Agonists; Fatty Liver; Hippocampus; Hypercholesterolemia; In Situ Nick-End Labeling; Inflammation; Insulin Resistance; Kainic Acid; Male; Mice; Mice, Inbred ICR; Neurons; Obesity; Oxidative Stress; Seizures	2015
Altered morphological dynamics of activated microglia after induction of status epilepticus. Journal of neuroinflammation, 2015, Nov-04, Volume: 12 Topics: Animals; Cell Movement; CX3C Chemokine Receptor 1; Excitatory Amino Acid Agonists; Hippocampus; In Vitro Techniques; Inflammation; Kainic Acid; Macrophage Activation; Mice; Mice, Inbred C57BL; Microglia; Purinergic P2Y Receptor Agonists; Receptors, Chemokine; Receptors, Purinergic P2Y12; Status Epilepticus	2015
Evidence for Status Epilepticus and Pro-Inflammatory Changes after Intranasal Kainic Acid Administration in Mice. PloS one, 2016, Volume: 11, Issue:3 Topics: Administration, Intranasal; Animals; Astrocytes; Behavior, Animal; Disease Models, Animal; Electroencephalography; Inflammation; Kainic Acid; Mice; Mice, Transgenic; Microglia; Status Epilepticus	2016
The Chemokine CCL2 Mediates the Seizure-enhancing Effects of Systemic Inflammation. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, Mar-30, Volume: 36, Issue:13 Topics: Animals; Antibodies; Benzoxazines; Chemokine CCL2; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Hippocampus; Indazoles; Inflammation; Kainic Acid; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Piperidines; Propionates; Receptors, CCR2; RNA, Messenger; Signal Transduction; Up-Regulation	2016
Leukocyte Infiltration Triggers Seizure Recurrence in a Rat Model of Temporal Lobe Epilepsy. Inflammation, 2016, Volume: 39, Issue:3 Topics: Animals; Blood-Brain Barrier; Brain; Disease Models, Animal; Epilepsy, Temporal Lobe; Inflammation; Kainic Acid; Leukocytes; Neurons; Rats; Recurrence; Seizures	2016
Confounding effect of EEG implantation surgery: Inadequacy of surgical control in a two hit model of temporal lobe epilepsy. Neuroscience letters, 2016, 05-27, Volume: 622 Topics: Animals; Dose-Response Relationship, Drug; Electrodes, Implanted; Electroencephalography; Epilepsy, Temporal Lobe; Hippocampus; Hyperthermia, Induced; Inflammation; Kainic Acid; Lipopolysaccharides; Mice, Inbred C57BL; Mice, Transgenic; Microglia	2016
Apolipoprotein D Overexpression Protects Against Kainate-Induced Neurotoxicity in Mice. Molecular neurobiology, 2017, Volume: 54, Issue:6 Topics: Animals; Apolipoproteins D; Apoptosis; Astrocytes; Cholesterol; Endocytosis; Hippocampus; Humans; Inflammation; Kainic Acid; Mice, Transgenic; Models, Biological; Neurons; Neuroprotection; Neurotoxins; Plasma Membrane Calcium-Transporting ATPases; Protein Subunits; Receptors, N-Methyl-D-Aspartate; Seizures; Up-Regulation	2017
CD200R/Foxp3-mediated signalling regulates microglial activation. Scientific reports, 2016, 10-12, Volume: 6 Topics: Animals; Anti-Inflammatory Agents; Antigens, CD; Cell Survival; Forkhead Transcription Factors; Green Fluorescent Proteins; Hippocampus; Inflammation; Kainic Acid; Male; Membrane Glycoproteins; Mice; Mice, Inbred ICR; Microglia; Neurons; Nitric Oxide; Phenotype; Signal Transduction; STAT3 Transcription Factor; STAT6 Transcription Factor	2016
Isoflurane prevents acquired epilepsy in rat models of temporal lobe epilepsy. Annals of neurology, 2016, Volume: 80, Issue:6 Topics: Animals; Blood-Brain Barrier; Disease Models, Animal; Electrocorticography; Epilepsy, Temporal Lobe; Female; Inflammation; Isoflurane; Kainic Acid; Magnetic Resonance Imaging; Male; Neuroimaging; Neurons; Paraoxon; Positron-Emission Tomography; Rats	2016
The anti-inflammatory role of extranuclear apurinic/apyrimidinic endonuclease 1/redox effector factor-1 in reactive astrocytes. Molecular brain, 2016, 12-16, Volume: 9, Issue:1 Topics: Acetylation; Animals; Anti-Inflammatory Agents; Astrocytes; Cells, Cultured; Cytoplasm; DNA-(Apurinic or Apyrimidinic Site) Lyase; E1A-Associated p300 Protein; Hippocampus; Humans; I-kappa B Kinase; Inflammation; Kainic Acid; Lipopolysaccharides; Nitric Oxide Synthase Type II; Protein Transport; Rats; Reactive Oxygen Species; Sequence Deletion; Signal Transduction; Subcellular Fractions; Transcription Factor RelA; Tumor Necrosis Factor-alpha	2016
Everolimus is better than rapamycin in attenuating neuroinflammation in kainic acid-induced seizures. Journal of neuroinflammation, 2017, 01-21, Volume: 14, Issue:1 Topics: Animals; Convulsants; Everolimus; Immunosuppressive Agents; Inflammation; Kainic Acid; Mice; Microglia; Seizures; Sirolimus; TOR Serine-Threonine Kinases	2017
Statin inhibits kainic acid-induced seizure and associated inflammation and hippocampal cell death. Neuroscience letters, 2008, Aug-08, Volume: 440, Issue:3 Topics: Animals; Atorvastatin; Cell Death; Disease Models, Animal; Dose-Response Relationship, Drug; Ectodysplasins; Heptanoic Acids; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Situ Nick-End Labeling; Inflammation; Interleukin-1beta; Kainic Acid; Male; Nitric Oxide Synthase Type II; Pyrroles; Rats; Rats, Sprague-Dawley; Seizures; Tumor Necrosis Factor-alpha	2008
Blueberry polyphenols attenuate kainic acid-induced decrements in cognition and alter inflammatory gene expression in rat hippocampus. Nutritional neuroscience, 2008, Volume: 11, Issue:4 Topics: Animals; Blueberry Plants; Cognition Disorders; Diet; Flavonoids; Fruit; Gene Expression; Hippocampus; Inflammation; Insulin-Like Growth Factor I; Interleukin-1beta; Kainic Acid; Male; Maze Learning; NF-kappa B; Phenols; Phytotherapy; Plant Extracts; Polyphenols; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha	2008
Activin A is essential for neurogenesis following neurodegeneration. Stem cells (Dayton, Ohio), 2009, Volume: 27, Issue:6 Topics: Activins; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Excitatory Amino Acid Agonists; Fluorescent Antibody Technique; Gliosis; Hippocampus; Inflammation; Kainic Acid; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Nerve Degeneration; Neurogenesis	2009
Kainic acid-induced F-344 rat model of mesial temporal lobe epilepsy: gene expression and canonical pathways. Toxicologic pathology, 2009, Volume: 37, Issue:6 Topics: Animals; Behavior, Animal; Cluster Analysis; Disease Models, Animal; Epilepsy, Temporal Lobe; Gene Expression Regulation; Hippocampus; Histocytochemistry; Inflammation; Kainic Acid; Male; Nerve Degeneration; Neuronal Plasticity; Rats; Rats, Inbred F344; Reproducibility of Results; Signal Transduction; Toxicogenetics	2009
Kainic acid-induced neurodegeneration and activation of inflammatory processes in organotypic hippocampal slice cultures: treatment with cyclooxygenase-2 inhibitor does not prevent neuronal death. Neuropharmacology, 2011, Volume: 60, Issue:7-8 Topics: Animals; Cell Culture Techniques; Cell Death; Cyclooxygenase 2 Inhibitors; Dinoprostone; Excitatory Amino Acid Agonists; Hippocampus; Inflammation; Kainic Acid; Male; Nerve Degeneration; Neurons; Nitrobenzenes; Rats; Rats, Sprague-Dawley; Sulfonamides	2011
Effect of inhibition of spinal cord glutamate transporters on inflammatory pain induced by formalin and complete Freund's adjuvant. Anesthesiology, 2011, Volume: 114, Issue:2 Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Blotting, Western; Disease Models, Animal; Formaldehyde; Freund's Adjuvant; Glutamic Acid; Inflammation; Kainic Acid; Male; Nicotinic Acids; Pain; Phosphoserine; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord	2011
Inflammation alters trafficking of extrasynaptic AMPA receptors in tonically firing lamina II neurons of the rat spinal dorsal horn. Pain, 2011, Volume: 152, Issue:4 Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biotinylation; Calcium; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Freund's Adjuvant; In Vitro Techniques; Inflammation; Kainic Acid; Male; Microscopy, Immunoelectron; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Receptors, AMPA; Spinal Cord	2011
Dietary supplementation with α-tocopherol reduces neuroinflammation and neuronal degeneration in the rat brain after kainic acid-induced status epilepticus. Free radical research, 2011, Volume: 45, Issue:10 Topics: alpha-Tocopherol; Animals; Antioxidants; Biological Availability; Brain; Dietary Supplements; Humans; Inflammation; Kainic Acid; Lipid Peroxidation; Male; Nerve Degeneration; Neurons; Oxidative Stress; Rats; Rats, Sprague-Dawley; Status Epilepticus	2011
Inflammatory changes during epileptogenesis and spontaneous seizures in a mouse model of mesiotemporal lobe epilepsy. Epilepsia, 2011, Volume: 52, Issue:12 Topics: Animals; Cell Death; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Eicosanoids; Epilepsy, Temporal Lobe; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hippocampus; Inflammation; Kainic Acid; Mice; Mice, Inbred C57BL; Plant Lectins; RNA, Messenger; Seizures; Signal Transduction; Time Factors	2011
Neuronal deletion of caspase 8 protects against brain injury in mouse models of controlled cortical impact and kainic acid-induced excitotoxicity. PloS one, 2011, Volume: 6, Issue:9 Topics: Animals; Blood-Brain Barrier; Brain Injuries; Caspase 8; Cell Death; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Gene Deletion; Gliosis; Inflammation; Kainic Acid; Memory; Mice; Neurons; Neurotoxins; Seizures; Tumor Necrosis Factor-alpha	2011
Intracranial V. cholerae sialidase protects against excitotoxic neurodegeneration. PloS one, 2011, Volume: 6, Issue:12 Topics: Animals; Anxiety; G(M1) Ganglioside; Gene Deletion; Inflammation; Kainic Acid; Memory; Mice; Motor Activity; Nerve Degeneration; Neuraminidase; Neuroprotective Agents; Neurotoxins; Sialyltransferases; Skull; Vibrio cholerae	2011
Urokinase-type plasminogen activator receptor modulates epileptogenesis in mouse model of temporal lobe epilepsy. Molecular neurobiology, 2013, Volume: 47, Issue:3 Topics: Animals; Apoptosis; Blood-Brain Barrier; Body Temperature; Cell Movement; Dentate Gyrus; Disease Models, Animal; Doublecortin Domain Proteins; Epilepsy, Temporal Lobe; Genotype; Inflammation; Kainic Acid; Macrophages; Male; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Mossy Fibers, Hippocampal; Nerve Degeneration; Neurogenesis; Neuropeptides; Receptors, Urokinase Plasminogen Activator; Status Epilepticus; Survival Analysis; T-Lymphocytes	2013
Neurotoxic effects of polymorphonuclear granulocytes on hippocampal primary cultures. Proceedings of the National Academy of Sciences of the United States of America, 2004, Jan-06, Volume: 101, Issue:1 Topics: Animals; Cell Death; Cell Survival; Cells, Cultured; Coculture Techniques; Hippocampus; Inflammation; Kainic Acid; Male; Neutrophils; Pancreatic Elastase; Protease Inhibitors; Rats; Rats, Sprague-Dawley	2004
Levetiracetam protects against kainic acid-induced toxicity. Life sciences, 2004, Jan-23, Volume: 74, Issue:10 Topics: Animals; Behavior, Animal; Brain; Cells, Cultured; Cerebral Cortex; Diencephalon; DNA Primers; Excitatory Amino Acid Agonists; Glutathione; Inflammation; Interleukin-1; Kainic Acid; Levetiracetam; Lipid Peroxidation; Macrophages; Male; Malondialdehyde; Neurons; Neurotoxicity Syndromes; Nootropic Agents; Piracetam; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA	2004
Nitric oxide synthase (NOS)-interacting protein interacts with neuronal NOS and regulates its distribution and activity. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Nov-17, Volume: 24, Issue:46 Topics: Animals; Brain; Carrier Proteins; Cells, Cultured; Chlorocebus aethiops; COS Cells; Epilepsy; Freund's Adjuvant; Hippocampus; Humans; Immunohistochemistry; In Vitro Techniques; Inflammation; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Synapses; Transfection; Ubiquitin-Protein Ligases	2004
Inflammatory response and glia activation in developing rat hippocampus after status epilepticus. Epilepsia, 2005, Volume: 46 Suppl 5 Topics: Animals; Animals, Newborn; Astrocytes; Blotting, Western; Cytokines; Disease Models, Animal; Gliosis; Hippocampus; Immunohistochemistry; Inflammation; Inflammation Mediators; Interleukin-6; Kainic Acid; Male; Nerve Degeneration; Neuroglia; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Status Epilepticus; Tumor Necrosis Factor-alpha	2005
Glial activation links early-life seizures and long-term neurologic dysfunction: evidence using a small molecule inhibitor of proinflammatory cytokine upregulation. Epilepsia, 2007, Volume: 48, Issue:9 Topics: Age Factors; Amino Acid Transport System X-AG; Animals; Astrocytes; Blotting, Western; Clusterin; Complement Factor H; Cytokines; Disease Models, Animal; Disease Susceptibility; Fluorescent Antibody Technique; Hippocampus; Immunohistochemistry; Inflammation; Kainic Acid; Male; Microglia; Neuroglia; Random Allocation; Rats; Rats, Sprague-Dawley; Seizures; Severity of Illness Index; Up-Regulation	2007
The role of defensins in the excitability of the peripheral vestibular system in the frog: evidence for the presence of communication between the immune and nervous systems. Hearing research, 2007, Volume: 230, Issue:1-2 Topics: Acetylcholine; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; alpha-Defensins; Animals; Atropine; Cholinergic Antagonists; Cycloleucine; Defensins; Dose-Response Relationship, Drug; Glutamic Acid; Humans; Immune System; In Vitro Techniques; Inflammation; Kainic Acid; N-Methylaspartate; Naloxone; Narcotic Antagonists; Neuroimmunomodulation; Neurons, Afferent; Rabbits; Rana temporaria; Receptors, Cholinergic; Receptors, Glutamate; Receptors, Opioid; Semicircular Canals; Synaptic Transmission; Vestibule, Labyrinth	2007
A synthetic kainoid, (2S,3R,4R)-3-carboxymethyl-4-(phenylthio)pyrrolidine-2-carboxylic acid (PSPA-1) serves as a novel anti-allodynic agent for neuropathic pain. European journal of pharmacology, 2007, Dec-01, Volume: 575, Issue:1-3 Topics: Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Hyperalgesia; Immunohistochemistry; Inflammation; Kainic Acid; Mice; Mononeuropathies; N-Methylaspartate; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Nociceptors; Pain; Spinal Cord; Time Factors	2007
Inflammation modifies status epilepticus-induced hippocampal injury during development. Epilepsia, 2007, Volume: 48 Suppl 8 Topics: Animals; Animals, Newborn; Brain; Disease Models, Animal; Hippocampus; Inflammation; Kainic Acid; Lipopolysaccharides; Lithium Chloride; Neurons; Pilocarpine; Rats; Status Epilepticus	2007
Differential blood-brain barrier breakdown and leucocyte recruitment following excitotoxic lesions in juvenile and adult rats. Experimental neurology, 1998, Volume: 154, Issue:1 Topics: Aging; Animals; Astrocytes; Biomarkers; Blood-Brain Barrier; Brain; Excitatory Amino Acid Agonists; Immunoenzyme Techniques; Inflammation; Kainic Acid; Leukocytes; Male; Microglia; N-Methylaspartate; Nerve Degeneration; Permeability; Rats; Rats, Wistar; Time Factors	1998