kainic acid has been researched along with Disease Exacerbation in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (52.17) | 29.6817 |
| 2010's | 11 (47.83) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diaz-Hernandez, M; Engel, T; Henshall, DC; Hessel, EV; Jimenez-Pacheco, A; Mesuret, G; Miras-Portugal, MT; Sanz-Rodriguez, A | 1 |
| Chen, YN; Lang, SY; Li, RS; Wang, XQ; Yang, N; Zhang, JT; Zhu, F; Zuo, PP | 1 |
| Amhaoul, H; Bertoglio, D; De Deyn, PP; Dedeurwaerdere, S; Geerts, E; Hamaide, J; Katsifis, A; Kumar-Singh, S; Reichel, SN; Staelens, S; Van Dam, D; Van Der Linden, A; Verhaeghe, J | 1 |
| Maguire, J; Sivakumaran, S | 1 |
| Bitsika, V; Depaulis, A; Duveau, V; Makridakis, M; Mermelekas, G; Mullen, W; Roucard, C; Savvopoulos, P; Simon-Areces, J; Vlahou, A | 1 |
| Ali, I; Amhaoul, H; Boets, S; Dedeurwaerdere, S; Janssens, P; Langlois, X; Van Eetveldt, A | 1 |
| Gröhn, O; Laitinen, T; Miettinen, T; Salo, RA; Sierra, A | 1 |
| Hattiangady, B; Rao, MS; Shetty, AK | 1 |
| Crawford, EL; Hsu, O; Mayer, D; Pfefferbaum, A; Rohlfing, T; Sullivan, EV; Vinco, S; Zahr, NM | 1 |
| Agostinho, PM; Cognato, GP; Cunha, RA; Hockemeyer, J; Müller, CE; Souza, DO | 1 |
| Muha, N; Ramsdell, JS | 1 |
| Raymick, J; Sarkar, S; Schmued, L | 1 |
| Binns, D; Cardamone, L; Hicks, RJ; Jones, N; Jupp, B; O'Brien, TJ; Rees, S; Williams, J | 1 |
| Corcoran, ME; Cui, SS; Hannesson, DK; Honer, WG; Saucier, DM; Schmued, LC; Wallace, AE; Zhang, X | 1 |
| Fernandez, SR; Siao, CJ; Tsirka, SE | 1 |
| Bakhiet, M; Chen, Z; Winblad, B; Yu, S; Zhu, J | 1 |
| Maidment, NT; Rocha, L | 1 |
| Shetty, AK; Shetty, GA; Zaman, V | 1 |
| Boison, D; Fritschy, JM; Gouder, N; Scheurer, L | 1 |
| Avanzini, G; Buzzi, A; Chikhladze, M; Franceschetti, S; Frassoni, C; Magnaghi, G; Paradiso, B; Sancini, G; Simonato, M; Zucchini, S | 1 |
| Ercan, F; Erkanli, G; Onat, F; Salik, E; San, T; Sirvanci, S; Yananli, HR | 1 |
| Busiguina, S; Carro, E; Torres-Aleman, I; Trejo, JL | 1 |
| Cadusseau, J; Grannec, G; Jamin, N; Junier, MP | 1 |
23 other study(ies) available for kainic acid and Disease Exacerbation
| Article | Year |
|---|---|
P2X7 receptor inhibition interrupts the progression of seizures in immature rats and reduces hippocampal damage.
Topics: Amygdala; Animals; Animals, Newborn; Bumetanide; Cell Death; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Hippocampus; Kainic Acid; Male; Purinergic P2X Receptor Antagonists; Pyridines; Quinazolines; Rats; Rats, Sprague-Dawley; Sodium Potassium Chloride Symporter Inhibitors; Status Epilepticus; Tetrazoles | 2014 |
Changes and overlapping distribution in the expression of CB1/OX1-GPCRs in rat hippocampus by kainic acid-induced status epilepticus.
Topics: Animals; Antigens, Nuclear; Cell Membrane; Disease Models, Animal; Disease Progression; Fluorescent Antibody Technique; Hippocampus; Immunohistochemistry; Indoles; Kainic Acid; Male; Nerve Tissue Proteins; Orexin Receptors; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptor, Cannabinoid, CB1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Status Epilepticus | 2015 |
Brain inflammation in a chronic epilepsy model: Evolving pattern of the translocator protein during epileptogenesis.
Topics: Animals; Autoradiography; Brain; Carrier Proteins; Chronic Disease; Disease Models, Animal; Disease Progression; Electrocorticography; Encephalitis; Epilepsy; Follow-Up Studies; Immunohistochemistry; Kainic Acid; Longitudinal Studies; Magnetic Resonance Imaging; Male; Nerve Degeneration; Neuroglia; Neurons; Positron-Emission Tomography; Rats, Wistar; Receptors, GABA-A | 2015 |
Bumetanide reduces seizure progression and the development of pharmacoresistant status epilepticus.
Topics: Animals; Anticonvulsants; Brain; Bumetanide; Diazepam; Disease Progression; Drug Resistant Epilepsy; Electroencephalography; Entorhinal Cortex; Excitatory Amino Acid Agonists; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Seizures; Sodium Potassium Chloride Symporter Inhibitors; Status Epilepticus | 2016 |
High-Throughput LC-MS/MS Proteomic Analysis of a Mouse Model of Mesiotemporal Lobe Epilepsy Predicts Microglial Activation Underlying Disease Development.
Topics: Animals; Chromatography, Liquid; Disease Models, Animal; Disease Progression; Epilepsy, Temporal Lobe; High-Throughput Screening Assays; Kainic Acid; Mice; Microglia; Neurodegenerative Diseases; Proteome; Proteomics; Synaptic Transmission; Tandem Mass Spectrometry; Time Factors | 2016 |
Metabotropic glutamate receptor 2/3 density and its relation to the hippocampal neuropathology in a model of temporal lobe epilepsy in rats.
Topics: Acute Disease; Amino Acids; Animals; Autoradiography; Chronic Disease; Cross-Sectional Studies; Disease Models, Animal; Disease Progression; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Male; Parietal Lobe; Radiopharmaceuticals; Rats, Wistar; Receptors, Metabotropic Glutamate; Thalamus; Time Factors; Tritium; Xanthenes | 2016 |
Diffusion tensor MRI shows progressive changes in the hippocampus and dentate gyrus after status epilepticus in rat - histological validation with Fourier-based analysis.
Topics: Animals; Anisotropy; Astrocytes; Brain Mapping; Dentate Gyrus; Diffusion Magnetic Resonance Imaging; Diffusion Tensor Imaging; Disease Progression; Fourier Analysis; Kainic Acid; Male; Nerve Fibers, Myelinated; Rats, Wistar; Status Epilepticus | 2017 |
Grafting of striatal precursor cells into hippocampus shortly after status epilepticus restrains chronic temporal lobe epilepsy.
Topics: Animals; Bromodeoxyuridine; Cell Count; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Disease Progression; Embryo, Mammalian; Epilepsy, Temporal Lobe; Fibroblast Growth Factor 2; Hippocampus; Kainic Acid; Nerve Tissue Proteins; Neurons; Neuropeptide Y; Rats; Rats, Inbred F344; Status Epilepticus; Stem Cell Transplantation; Stem Cells; Time Factors | 2008 |
In vivo glutamate decline associated with kainic acid-induced status epilepticus.
Topics: Analysis of Variance; Animals; Aspartic Acid; Disease Progression; Glutamic Acid; Hippocampus; Image Processing, Computer-Assisted; Immunohistochemistry; Kainic Acid; Lactic Acid; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurons; Organ Size; Rats; Rats, Wistar; Seizures; Status Epilepticus; Time Factors | 2009 |
Caffeine and an adenosine A(2A) receptor antagonist prevent memory impairment and synaptotoxicity in adult rats triggered by a convulsive episode in early life.
Topics: Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Animals, Newborn; Caffeine; Disease Models, Animal; Disease Progression; Drug Administration Schedule; Glial Fibrillary Acidic Protein; Kainic Acid; Memory Disorders; Neurotoxicity Syndromes; Phosphodiesterase Inhibitors; Purines; Pyrimidines; Qa-SNARE Proteins; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Synapses; Synaptophysin; Synaptosomal-Associated Protein 25; Triazoles; Tritium; Xanthines | 2010 |
Domoic acid induced seizures progress to a chronic state of epilepsy in rats.
Topics: Animals; Disease Models, Animal; Disease Progression; Epilepsy; Kainic Acid; Male; Marine Toxins; Neurotoxins; Rats; Rats, Sprague-Dawley; Seizures; Videotape Recording | 2011 |
Temporal progression of kainic acid induced changes in vascular laminin expression in rat brain with neuronal and glial correlates.
Topics: Animals; Astrocytes; Blood-Brain Barrier; Cerebral Arteries; Disease Models, Animal; Disease Progression; Glial Fibrillary Acidic Protein; Gliosis; Kainic Acid; Laminin; Male; Nerve Degeneration; Neurotoxins; Rats; Rats, Sprague-Dawley; Time Factors; Up-Regulation | 2012 |
Hypometabolism precedes limbic atrophy and spontaneous recurrent seizures in a rat model of TLE.
Topics: Analysis of Variance; Animals; Atrophy; Brain Mapping; CA1 Region, Hippocampal; Disease Models, Animal; Disease Progression; Electroencephalography; Electron Transport Complex IV; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Fluorodeoxyglucose F18; Glial Fibrillary Acidic Protein; Glucose Metabolism Disorders; Glucose Transporter Type 1; Kainic Acid; Limbic System; Magnetic Resonance Imaging; Male; Positron-Emission Tomography; Pyramidal Cells; Rats; Rats, Wistar; Synaptophysin; Time Factors | 2012 |
Relations between brain pathology and temporal lobe epilepsy.
Topics: Animals; Brain; Cell Death; Cell Survival; Chronic Disease; Disease Models, Animal; Disease Progression; Epilepsy, Temporal Lobe; Kainic Acid; Limbic System; Male; Mossy Fibers, Hippocampal; Neurons; Pilocarpine; Rats; Rats, Inbred F344; Rats, Wistar; Reaction Time; Recurrence; Survival Rate | 2002 |
Cell type-specific roles for tissue plasminogen activator released by neurons or microglia after excitotoxic injury.
Topics: Animals; Cell Count; Cells, Cultured; Disease Progression; Gene Expression; Genes, fms; Genetic Predisposition to Disease; Kainic Acid; Mice; Mice, Knockout; Mice, Transgenic; Microglia; Neurodegenerative Diseases; Neurofilament Proteins; Neurons; Neurotoxins; Organ Specificity; Promoter Regions, Genetic; Tissue Plasminogen Activator | 2003 |
The chemokine receptor CCR5 is not a necessary inflammatory mediator in kainic acid-induced hippocampal injury: evidence for a compensatory effect by increased CCR2 and CCR3.
Topics: Animals; Cell Survival; Cells, Cultured; Disease Progression; Excitatory Amino Acid Agonists; Hippocampus; Inflammation Mediators; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurodegenerative Diseases; Neurons; Receptors, CCR2; Receptors, CCR3; Receptors, CCR5; Receptors, Chemokine; RNA, Messenger | 2003 |
Opioid peptide release in the rat hippocampus after kainic acid-induced status epilepticus.
Topics: Animals; Disease Models, Animal; Disease Progression; Down-Regulation; Dynorphins; Enkephalins; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Opioid Peptides; Rats; Rats, Wistar; Reaction Time; Status Epilepticus | 2003 |
Hippocampal neurotrophin levels in a kainate model of temporal lobe epilepsy: a lack of correlation between brain-derived neurotrophic factor content and progression of aberrant dentate mossy fiber sprouting.
Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Disease Progression; Epilepsy, Temporal Lobe; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Mossy Fibers, Hippocampal; Nerve Growth Factor; Nerve Growth Factors; Neurotrophin 3; Rats; Rats, Inbred F344 | 2003 |
Overexpression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis.
Topics: Action Potentials; Adenosine A1 Receptor Antagonists; Adenosine Kinase; Animals; Anticonvulsants; Astrocytes; Brain; Disease Models, Animal; Disease Progression; Electroencephalography; Enzyme Inhibitors; Epilepsy, Temporal Lobe; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Kainic Acid; Mice; Neurons; Tubercidin; Xanthines | 2004 |
A pathogenetic hypothesis of Unverricht-Lundborg disease onset and progression.
Topics: Animals; Cystatin B; Cystatins; Disease Models, Animal; Disease Progression; Electrophysiology; Epilepsies, Myoclonic; Excitatory Amino Acid Agonists; Genetic Predisposition to Disease; Hippocampus; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Nerve Degeneration; Neurons; Organ Culture Techniques; Unverricht-Lundborg Syndrome | 2007 |
Time-dependent changes in distribution of basic fibroblast growth factor immunoreactive cells in hippocampus after kainic acid injection in rat pups.
Topics: Animals; Animals, Newborn; Astrocytes; Cell Count; Cell Death; Disease Progression; Down-Regulation; Fibroblast Growth Factor 2; Gliosis; Hippocampus; Immunohistochemistry; Kainic Acid; Nerve Degeneration; Neurons; Neurotoxins; Pyramidal Cells; Rats; Rats, Wistar; Seizures; Time Factors | 2007 |
Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy.
Topics: Animals; Behavior, Animal; Cell Count; Cerebellar Diseases; Disease Models, Animal; Disease Progression; Glucose; Hippocampus; Immunohistochemistry; Injections, Subcutaneous; Insulin-Like Growth Factor I; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Olivary Nucleus; Physical Conditioning, Animal; Purkinje Cells; Pyridines; Rats; Rats, Wistar; Treatment Outcome | 2001 |
Two temporal stages of oligodendroglial response to excitotoxic lesion in the gray matter of the adult rat brain.
Topics: Animals; Apoptosis; Astrocytes; bcl-2-Associated X Protein; Brain; Cell Count; Demyelinating Diseases; Disease Progression; Female; In Situ Nick-End Labeling; Kainic Acid; Macrophages; Microglia; Myelin Sheath; Necrosis; Oligodendroglia; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Thalamus; Time Factors | 2001 |