kainic acid has been researched along with Chronic Disease in 60 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.67) | 18.7374 |
| 1990's | 12 (20.00) | 18.2507 |
| 2000's | 24 (40.00) | 29.6817 |
| 2010's | 20 (33.33) | 24.3611 |
| 2020's | 3 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Braine, EL; Casillas-Espinosa, PM; Curl, CL; Delbridge, LM; Gomes, FM; Jones, NC; Liu, Z; Macefield, VG; O'Brien, TJ; Powell, KL; Raaijmakers, AJA; Sharma, P; Sivathamboo, S | 1 |
| Ampig, K; Bui, AD; Ciernia, AV; Felong, S; Gschwind, T; Kim, HK; Nguyen, TM; Soltesz, I; Suh, D; Wood, MA | 1 |
| Cheng, W; Gao, Y; Li, S; Wang, X; Zhang, Y | 1 |
| Anderson, AE; Davanger, S; Dosa, ZJ; Egbenya, DL; Hussain, S; Lai, YC; Sørensen, JB | 1 |
| Chi, Y; Guan, J; Guo, Y; Li, X; Lu, Z; Rao, J; Wu, B; Xiao, K; Xu, Q; Xu, Y; Xue, S | 1 |
| Davanger, S; Egbenya, DL; Hammer, J; Lorgen, JØ | 1 |
| Jia, YJ; Li, TR; Lv, RJ; Ma, C; Qiu, WY; Shao, XQ; Wang, Q | 1 |
| Abramov, AY; Christian Wigley, W; Gola, L; Kovac, S; Lieb, A; Shekh-Ahmad, T; Walker, MC | 1 |
| Buckmaster, PS; Gulland, FM; Toyoda, I; Van Bonn, W; Wen, X | 1 |
| MacKenzie, G; Maguire, J | 1 |
| Day, B; Fulton, R; Liang, LP; Patel, M; Rowley, S; Shimizu, T | 1 |
| Bankstahl, M; Klein, S; Löscher, W; Römermann, K; Twele, F | 1 |
| Amhaoul, H; Bertoglio, D; De Deyn, PP; Dedeurwaerdere, S; Geerts, E; Hamaide, J; Katsifis, A; Kumar-Singh, S; Reichel, SN; Staelens, S; Van Dam, D; Van Der Linden, A; Verhaeghe, J | 1 |
| Andrade, JP; Andrade, PA; Leite, JF; Lukoyanov, NV; Luz, LL; Maia, GH; Soares, JI | 1 |
| Ali, I; Amhaoul, H; Boets, S; Dedeurwaerdere, S; Janssens, P; Langlois, X; Van Eetveldt, A | 1 |
| Dudek, FE; Hellier, JL; Staley, KJ; White, A; Williams, PA | 1 |
| Clark, S; Dudek, FE; Ferraro, DJ; Staley, KJ; Swiercz, W; White, AM; Williams, PA | 1 |
| Hattiangady, B; Shetty, AK | 1 |
| Boison, D; Lan, JQ; Li, T | 1 |
| Clark, S; Dudek, FE; Hellier, JL; Staley, KJ; White, A; Williams, PA | 1 |
| Kuzhandaivel, A; Margaryan, G; Mladinic, M; Nistri, A; Taccola, G | 1 |
| De Guise, S; Draghi, A; Gulland, FM; Jessup, D; Joshi, D; Levin, M | 1 |
| Kanamori, K; Ross, BD | 1 |
| Hou, X; Lin, Z; Lu, D; Na, M; Qiao, W; Song, Y; Sun, J; Wei, L; Xie, C | 1 |
| Brotons-Mas, JR; Cid, E; de la Prida, LM; Gal, B; Gómez-Domínguez, D; Inostroza, M; Solís, JM; Suárez, LM | 1 |
| Alvestad, S; Amiry-Moghaddam, M; Hammer, J; Hoddevik, EH; Ottersen, OP; Skare, Ø; Sonnewald, U | 1 |
| Corcoran, ME; Cui, SS; Hannesson, DK; Honer, WG; Saucier, DM; Schmued, LC; Wallace, AE; Zhang, X | 1 |
| Jasmin, L; Larson, AA; Ohara, PT; Tien, D | 1 |
| Shetty, AK; Zaman, V | 1 |
| Cavazos, JE; Cross, DJ; Jones, SM | 1 |
| Benesová, P; Betka, J; Langmeier, M; Trojan, S | 1 |
| Chapman, PL; Dudek, FE; Ferraro, DJ; Grabenstatter, HL; Williams, PA | 1 |
| Antal, K; Arabadzisz, D; Emri, Z; Fritschy, JM; Parpan, F | 1 |
| da Silva, FH; Gorter, JA; Kalitzin, SN; Kloosterman, F; Tolner, EA | 1 |
| Almajano, J; Azizyan, A; Bragin, A; Engel, J; Wilson, CL | 1 |
| Joseph, SA; Siddiqui, AH | 1 |
| Fornai, F; Giorgi, FS; Iudice, A; Lazzeri, G; Murri, L; Natale, G; Paparelli, A; Ruggieri, S | 1 |
| Alvestad, S; Eyjolfsson, E; Hammer, J; Ottersen, OP; Qu, H; Sonnewald, U | 1 |
| Einula, C; Gröhn, OH; Immonen, RJ; Kharatishvili, I; Pitkänen, A; Sierra, A | 1 |
| Behrens, CJ; Friedman, A; Gross, M; Heinemann, U; Ivens, S; Njunting, M; Soreq, H; Tolner, E; Tolner, EA; Zimmerman, G | 1 |
| Depaulis, A; Devaux, B; Pallud, J | 1 |
| Cai, Z; Hersey, K; Rhodes, PG; Sigrest, T | 1 |
| Bernard, C; Wheal, HV | 1 |
| Civenni, G; Messali, S; Monno, A; Rizzi, M; Samanin, R; Vezzani, A | 1 |
| Chen, Q; Leahy, JC; Vallano, ML | 1 |
| Drewes, LR; Gerhart, DZ; Gronlund, KM; Leino, RL; McCall, AL | 1 |
| Ben-Ari, Y; Bernard, CL; Esclapez, M; Gozlan, H; Hirsch, JC; Quesada, O | 1 |
| Atweh, SF; Bahuth, NB; Jabbur, SJ; Saadé, NE | 1 |
| Babb, TL; Christi, W; Mikuni, N | 1 |
| Ikemoto, M; Nakata, H; Ochiishi, T; Suzuki, SS; Takita, M | 1 |
| Giovengo, SL; Kovacs, KJ; Larson, AA; Shi, Q; Velázquez, RA | 1 |
| Bragin, A; Engel, J; Wilson, CL | 1 |
| Golarai, G; Lynch, M; Sayin, U; Sutula, T | 1 |
| Doi, T; Kamada, H; Mitsuyama, Y; Nakajima, A; Ohya-Nishiguchi, H; Tokumaru, J; Ueda, Y; Willmore, LJ; Yokoyama, H | 1 |
| Bernard, C; Marsden, DP; Wheal, HV | 1 |
| Bragin, A; Engel, J; Mody, I; Wilson, CL | 1 |
| Haruhiko, S; Hitoshi, A; Michiko, I; Shin, K | 1 |
| Dodd, PR; Johnston, GA; Maddison, JE; Watson, WE | 1 |
| Simpson, LH; Wheal, HV; Williamson, R | 1 |
| Tanaka, S; Tanaka, T; Yonemasu, Y | 1 |
2 review(s) available for kainic acid and Chronic Disease
| Article | Year |
|---|---|
MDMA and seizures: a dangerous liaison?
Topics: Acute Disease; Animals; Chronic Disease; Disease Susceptibility; Drug Interactions; Hallucinogens; Kainic Acid; Mice; Mossy Fibers, Hippocampal; N-Methyl-3,4-methylenedioxyamphetamine; Seizures | 2006 |
[Changes in spontaneous epileptic activity after selective intrahippocampal transection in a model of chronic mesial temporal lobe epilepsy].
Topics: Animals; Chronic Disease; Disease Models, Animal; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Kindling, Neurologic; Mice; Neuronal Plasticity; Neurosurgical Procedures | 2008 |
58 other study(ies) available for kainic acid and Chronic Disease
| Article | Year |
|---|---|
Altered cardiac structure and function is related to seizure frequency in a rat model of chronic acquired temporal lobe epilepsy.
Topics: Animals; Chronic Disease; Diastole; Disease Models, Animal; Echocardiography; Electrocardiography; Electroencephalography; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Fibrosis; Heart Rate; Kainic Acid; Mitral Valve; Myocardium; Rats; Status Epilepticus; Sudden Unexpected Death in Epilepsy; Ventricular Dysfunction; Ventricular Remodeling; Video Recording | 2021 |
Optogenetic intervention of seizures improves spatial memory in a mouse model of chronic temporal lobe epilepsy.
Topics: Animals; Channelrhodopsins; Chronic Disease; Cognitive Dysfunction; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Hippocampus; Interneurons; Kainic Acid; Mice; Optogenetics; Parvalbumins; Spatial Learning; Spatial Memory; Video Recording | 2020 |
Decreased excitatory drive onto hilar neuronal nitric oxide synthase expressing interneurons in chronic models of epilepsy.
Topics: Animals; Chronic Disease; Convulsants; Epilepsy; Excitatory Postsynaptic Potentials; Gene Expression Regulation, Enzymologic; Hippocampus; Humans; Interneurons; Kainic Acid; Male; Mice; Mice, Transgenic; Nitric Oxide Synthase Type I; Patch-Clamp Techniques; Pilocarpine; Rats, Sprague-Dawley | 2021 |
The calcium sensor synaptotagmin 1 is expressed and regulated in hippocampal postsynaptic spines.
Topics: Animals; Cells, Cultured; Chronic Disease; Cytoplasmic Vesicles; Dendritic Spines; Disease Models, Animal; Down-Regulation; Epilepsy, Temporal Lobe; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Mice, Knockout; Microscopy, Electron; Post-Synaptic Density; Presynaptic Terminals; Rats, Sprague-Dawley; Rats, Wistar; Synaptotagmin I | 2017 |
Establishment of a rhesus monkey model of chronic temporal lobe epilepsy using repetitive unilateral intra-amygdala kainic acid injections.
Topics: Amygdala; Animals; Chronic Disease; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Epilepsy, Temporal Lobe; Functional Laterality; Gliosis; Infusion Pumps, Implantable; Kainic Acid; Macaca mulatta; Male; Neurosurgical Procedures; Pyramidal Cells; Seizures; Temporal Lobe | 2017 |
PICK1 facilitates lasting reduction in GluA2 concentration in the hippocampus during chronic epilepsy.
Topics: Animals; Blotting, Western; Carrier Proteins; Chronic Disease; Cytoskeletal Proteins; Disease Models, Animal; Down-Regulation; Epilepsy; Hippocampus; Kainic Acid; Male; Multivariate Analysis; Neurons; Nuclear Proteins; Rats, Wistar; Receptors, AMPA; Regression Analysis; Tubulin | 2017 |
The role of the microRNA-146a/complement factor H/interleukin-1β-mediated inflammatory loop circuit in the perpetuate inflammation of chronic temporal lobe epilepsy.
Topics: Animals; Case-Control Studies; Cell Line; Chronic Disease; Complement Factor H; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Gene Knockdown Techniques; Hippocampus; Humans; Inflammation; Interleukin-1beta; Kainic Acid; Male; MicroRNAs; Rats, Sprague-Dawley; Up-Regulation | 2018 |
Combination antioxidant therapy prevents epileptogenesis and modifies chronic epilepsy.
Topics: Animals; Antioxidants; Biomarkers; Chronic Disease; Epilepsy; Kainic Acid; Leprostatic Agents; Male; NADPH Oxidases; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Reactive Oxygen Species | 2019 |
Hippocampal neuropathology of domoic acid-induced epilepsy in California sea lions (Zalophus californianus).
Topics: Age Factors; Animals; Cell Count; Chronic Disease; Epilepsy; Epilepsy, Temporal Lobe; Female; Functional Laterality; Hippocampus; Humans; Kainic Acid; Male; Marine Toxins; Neurons; Organ Size; Sclerosis; Sea Lions; Sex Factors; Somatostatin; Species Specificity | 2014 |
Chronic stress shifts the GABA reversal potential in the hippocampus and increases seizure susceptibility.
Topics: Acute Disease; Animals; Bumetanide; Chronic Disease; Corticosterone; Disease Models, Animal; gamma-Aminobutyric Acid; Hippocampus; K Cl- Cotransporters; Kainic Acid; Male; Membrane Potentials; Mice, Inbred C57BL; Phosphorylation; Pyramidal Cells; Restraint, Physical; Seizures; Sodium Potassium Chloride Symporter Inhibitors; Solute Carrier Family 12, Member 2; Stress, Psychological; Symporters | 2015 |
Mitochondrial respiration deficits driven by reactive oxygen species in experimental temporal lobe epilepsy.
Topics: Acute Disease; Animals; Antioxidants; Cell Respiration; Chronic Disease; Disease Models, Animal; Epilepsy, Temporal Lobe; Female; Glycolysis; Hippocampus; Kainic Acid; Male; Mice, Knockout; Mitochondria; Oxygen; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase | 2015 |
The AMPA receptor antagonist NBQX exerts anti-seizure but not antiepileptogenic effects in the intrahippocampal kainate mouse model of mesial temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Chronic Disease; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Female; Hippocampus; Kainic Acid; Mice; Nitriles; Phenytoin; Pyridones; Quinoxalines; Receptors, AMPA; Seizures; Status Epilepticus | 2015 |
Brain inflammation in a chronic epilepsy model: Evolving pattern of the translocator protein during epileptogenesis.
Topics: Animals; Autoradiography; Brain; Carrier Proteins; Chronic Disease; Disease Models, Animal; Disease Progression; Electrocorticography; Encephalitis; Epilepsy; Follow-Up Studies; Immunohistochemistry; Kainic Acid; Longitudinal Studies; Magnetic Resonance Imaging; Male; Nerve Degeneration; Neuroglia; Neurons; Positron-Emission Tomography; Rats, Wistar; Receptors, GABA-A | 2015 |
Altered taste preference and loss of limbic-projecting serotonergic neurons in the dorsal raphe nucleus of chronically epileptic rats.
Topics: Anhedonia; Animals; Cell Count; Chronic Disease; Depressive Disorder; Disease Models, Animal; Dorsal Raphe Nucleus; Electrocorticography; Epilepsy; Immunohistochemistry; Kainic Acid; Male; Random Allocation; Rats, Wistar; Seizures; Serotonergic Neurons; Status Epilepticus; Taste Perception | 2016 |
Metabotropic glutamate receptor 2/3 density and its relation to the hippocampal neuropathology in a model of temporal lobe epilepsy in rats.
Topics: Acute Disease; Amino Acids; Animals; Autoradiography; Chronic Disease; Cross-Sectional Studies; Disease Models, Animal; Disease Progression; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Male; Parietal Lobe; Radiopharmaceuticals; Rats, Wistar; Receptors, Metabotropic Glutamate; Thalamus; Time Factors; Tritium; Xanthenes | 2016 |
NMDA receptor-mediated long-term alterations in epileptiform activity in experimental chronic epilepsy.
Topics: Analysis of Variance; Animals; Biphenyl Compounds; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Electroencephalography; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Kainic Acid; Long-Term Synaptic Depression; Male; Propionates; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors; Wakefulness | 2009 |
Development of spontaneous recurrent seizures after kainate-induced status epilepticus.
Topics: Action Potentials; Animals; Brain; Chronic Disease; Convulsants; Disease Models, Animal; Electric Stimulation; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Neurons; Rats; Rats, Sprague-Dawley; Recurrence; Seizures; Signal Processing, Computer-Assisted; Status Epilepticus; Telemetry; Time Factors | 2009 |
Decreased neuronal differentiation of newly generated cells underlies reduced hippocampal neurogenesis in chronic temporal lobe epilepsy.
Topics: Animals; Astrocytes; Cell Differentiation; Cell Survival; Chronic Disease; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Kainic Acid; Microglia; Neurogenesis; Neurons; Oligodendroglia; Rats; Rats, Inbred F344; Stem Cell Niche; Stem Cells; Time Factors | 2010 |
Uncoupling of astrogliosis from epileptogenesis in adenosine kinase (ADK) transgenic mice.
Topics: Adenosine Kinase; Animals; Astrocytes; Brain; Cell Death; Chronic Disease; Epilepsy; Gliosis; Kainic Acid; Male; Mice; Mice, Knockout; Mice, Transgenic; Pyramidal Cells; Recurrence; Seizures; Severity of Illness Index; Status Epilepticus; Time Factors; Tissue Distribution; Transgenes; Up-Regulation | 2008 |
EEG spike activity precedes epilepsy after kainate-induced status epilepticus.
Topics: Action Potentials; Animals; Biomarkers; Brain Injuries; Chronic Disease; Dentate Gyrus; Disease Models, Animal; Electroencephalography; Epilepsy; Humans; Kainic Acid; Male; Monitoring, Physiologic; Rats; Rats, Sprague-Dawley; Recurrence; Signal Processing, Computer-Assisted; Status Epilepticus; Telemetry; Time Factors; Video Recording | 2010 |
Deconstructing locomotor networks with experimental injury to define their membership.
Topics: Animals; Animals, Newborn; Chronic Disease; Convulsants; Excitatory Amino Acid Agonists; Glutamates; Interneurons; Kainic Acid; Locomotion; Lumbar Vertebrae; Nerve Net; Neurons; Neurotoxins; Rats; Spinal Cord Injuries; Strychnine; Wounds and Injuries | 2010 |
Immunomodulatory effects upon in vitro exposure of California sea lion and southern sea otter peripheral blood leukocytes to domoic acid.
Topics: Animals; Animals, Wild; Cell Proliferation; Cells, Cultured; Chronic Disease; Conservation of Natural Resources; Dose-Response Relationship, Drug; Female; Immunomodulation; Kainic Acid; Leukocytes; Male; Neuromuscular Depolarizing Agents; Otters; Phagocytosis; Respiratory Burst; Sea Lions; Species Specificity; T-Lymphocytes | 2010 |
Chronic electrographic seizure reduces glutamine and elevates glutamate in the extracellular fluid of rat brain.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Chronic Disease; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Extracellular Fluid; Glutamic Acid; Glutamine; Hippocampus; Intracellular Fluid; Kainic Acid; Male; Microdialysis; Neurotoxins; Rats; Rats, Wistar; Synaptic Vesicles | 2011 |
Administration of simvastatin after kainic acid-induced status epilepticus restrains chronic temporal lobe epilepsy.
Topics: Animals; Anticholesteremic Agents; Behavior, Animal; Chronic Disease; Cytokines; Enzyme-Linked Immunosorbent Assay; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Kainic Acid; Male; Mossy Fibers, Hippocampal; Neurons; Rats; Rats, Wistar; Simvastatin; Status Epilepticus | 2011 |
Systemic injection of kainic acid differently affects LTP magnitude depending on its epileptogenic efficiency.
Topics: Animals; Chronic Disease; Disease Resistance; Electroencephalography; Hippocampus; In Vitro Techniques; Kainic Acid; Long-Term Potentiation; Male; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Recognition, Psychology; Status Epilepticus; Synaptic Transmission; Theta Rhythm | 2012 |
Mislocalization of AQP4 precedes chronic seizures in the kainate model of temporal lobe epilepsy.
Topics: Animals; Aquaporin 4; Astrocytes; Cell Polarity; Chronic Disease; Disease Models, Animal; Epilepsy, Temporal Lobe; Kainic Acid; Male; Rats; Rats, Sprague-Dawley; Seizures | 2013 |
Relations between brain pathology and temporal lobe epilepsy.
Topics: Animals; Brain; Cell Death; Cell Survival; Chronic Disease; Disease Models, Animal; Disease Progression; Epilepsy, Temporal Lobe; Kainic Acid; Limbic System; Male; Mossy Fibers, Hippocampal; Neurons; Pilocarpine; Rats; Rats, Inbred F344; Rats, Wistar; Reaction Time; Recurrence; Survival Rate | 2002 |
Vagal afferents are necessary for the establishment but not the maintenance of kainic acid-induced hyperalgesia in mice.
Topics: Animals; Brain; Cell Count; Cell Death; Chronic Disease; Disease Models, Animal; Hyperalgesia; Immunohistochemistry; In Situ Nick-End Labeling; Kainic Acid; Male; Mice; Mice, Inbred Strains; Mitogen-Activated Protein Kinases; Neurons, Afferent; Nodose Ganglion; Oncogene Proteins v-fos; Pain Measurement; Spinal Cord; Vagotomy; Vagus Nerve | 2003 |
Pretreatment of donor cells with FGF-2 enhances survival of fetal hippocampal CA3 cell transplants in the chronically lesioned young adult hippocampus.
Topics: Animals; Brain Tissue Transplantation; Bromodeoxyuridine; Cell Count; Cell Survival; Cells, Cultured; Chronic Disease; Epilepsy, Temporal Lobe; Fetal Tissue Transplantation; Fibroblast Growth Factor 2; Graft Survival; Hippocampus; Kainic Acid; Male; Neurons; Rats; Rats, Inbred F344 | 2003 |
Sprouting and synaptic reorganization in the subiculum and CA1 region of the hippocampus in acute and chronic models of partial-onset epilepsy.
Topics: Acute Disease; Animals; Chronic Disease; Convulsants; Disease Models, Animal; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Hippocampus; Immunohistochemistry; Injections, Intraventricular; Kainic Acid; Kindling, Neurologic; Male; Muscarinic Antagonists; Nerve Regeneration; Neural Pathways; Neuronal Plasticity; Pentylenetetrazole; Pilocarpine; Rats; Rats, Sprague-Dawley; Synapses | 2004 |
Long-lasting changes in the density of nitrergic neurons following kainic acid administration and chronic hypoxia.
Topics: Animals; Auditory Cortex; Cell Count; Chronic Disease; Hippocampus; Hypoxia; Injections, Intraperitoneal; Kainic Acid; Male; Nitrergic Neurons; Rats; Rats, Wistar; Time Factors | 2005 |
Use of chronic epilepsy models in antiepileptic drug discovery: the effect of topiramate on spontaneous motor seizures in rats with kainate-induced epilepsy.
Topics: Animals; Anticonvulsants; Chronic Disease; Cross-Over Studies; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Epilepsy; Fructose; Injections, Intraperitoneal; Kainic Acid; Pilocarpine; Rats; Rats, Sprague-Dawley; Research Design; Sodium Chloride; Status Epilepticus; Topiramate | 2005 |
Epileptogenesis and chronic seizures in a mouse model of temporal lobe epilepsy are associated with distinct EEG patterns and selective neurochemical alterations in the contralateral hippocampus.
Topics: Action Potentials; Animals; Brain Chemistry; Calbindins; Chronic Disease; Disease Models, Animal; Down-Regulation; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Functional Laterality; Galanin; Hippocampus; Kainic Acid; Mice; Mossy Fibers, Hippocampal; Nerve Degeneration; Neural Pathways; Neuropeptide Y; Neurotoxins; Pyramidal Cells; S100 Calcium Binding Protein G; Sincalide; Status Epilepticus; Theta Rhythm; Up-Regulation | 2005 |
Physiological changes in chronic epileptic rats are prominent in superficial layers of the medial entorhinal area.
Topics: Animals; Cell Count; Cell Death; Chronic Disease; Disease Models, Animal; Electric Stimulation; Entorhinal Cortex; Epilepsy; Evoked Potentials; Hippocampus; Kainic Acid; Male; Neural Pathways; Neurons; Rats; Rats, Sprague-Dawley | 2005 |
Analysis of chronic seizure onsets after intrahippocampal kainic acid injection in freely moving rats.
Topics: Animals; Behavior, Animal; Chronic Disease; Cortical Synchronization; Dentate Gyrus; Electrodes, Implanted; Electroencephalography; Entorhinal Cortex; Functional Laterality; Hippocampus; Kainic Acid; Microinjections; Motor Activity; Rats; Rats, Wistar; Seizures; Synaptic Transmission | 2005 |
CA3 axonal sprouting in kainate-induced chronic epilepsy.
Topics: Animals; Axons; Cell Count; Chronic Disease; Coloring Agents; Dentate Gyrus; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; Horseradish Peroxidase; Immunohistochemistry; Kainic Acid; Male; Mossy Fibers, Hippocampal; Phytohemagglutinins; Rats; Rats, Sprague-Dawley; Seizures | 2005 |
Limbic structures show altered glial-neuronal metabolism in the chronic phase of kainate induced epilepsy.
Topics: Animals; Carbon Isotopes; Chronic Disease; Epilepsy; Kainic Acid; Limbic System; Magnetic Resonance Spectroscopy; Male; Neuroglia; Neurons; Protons; Rats; Rats, Sprague-Dawley | 2008 |
Manganese enhanced MRI detects mossy fiber sprouting rather than neurodegeneration, gliosis or seizure-activity in the epileptic rat hippocampus.
Topics: Algorithms; Animals; Blood-Brain Barrier; Chlorides; Chronic Disease; Contrast Media; Data Interpretation, Statistical; Dentate Gyrus; Electroencephalography; Epilepsy; Excitatory Amino Acid Agonists; Gadolinium; Gliosis; Kainic Acid; Magnetic Resonance Imaging; Male; Manganese Compounds; Mossy Fibers, Hippocampal; Nerve Degeneration; Rats; Rats, Wistar; Seizures; Status Epilepticus | 2008 |
Acetylcholine-induced seizure-like activity and modified cholinergic gene expression in chronically epileptic rats.
Topics: Acetylcholine; Acetylcholinesterase; Alternative Splicing; Animals; Chronic Disease; Convulsants; Electrophysiology; Entorhinal Cortex; Epilepsy; Gene Expression; Kainic Acid; Microelectrodes; Muscarinic Antagonists; Nicotinic Antagonists; Organ Culture Techniques; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seizures | 2008 |
Intrauterine hypoxia-ischemia increases N-methyl-D-aspartate-induced cGMP formation and glutamate accumulation in cultured rat cerebellar granule cells.
Topics: Animals; Arginine; Brain Ischemia; Cells, Cultured; Cerebellar Diseases; Chronic Disease; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Fetal Hypoxia; Gestational Age; Glutamic Acid; Hypoxia, Brain; Kainic Acid; N-Methylaspartate; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1995 |
Plasticity of AMPA and NMDA receptor-mediated epileptiform activity in a chronic model of temporal lobe epilepsy.
Topics: Animals; Chronic Disease; Disease Models, Animal; Electric Stimulation; Epilepsy, Temporal Lobe; Hippocampus; Humans; In Vitro Techniques; Kainic Acid; Long-Term Potentiation; Male; Neuronal Plasticity; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tetany | 1995 |
Enhanced neuropeptide Y release in the hippocampus is associated with chronic seizure susceptibility in kainic acid treated rats.
Topics: Animals; Antibodies; Chronic Disease; Disease Susceptibility; Dose-Response Relationship, Drug; Electrophysiology; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Neurons; Neuropeptide Y; Pentylenetetrazole; Potassium Chloride; Rats; Rats, Sprague-Dawley; Seizures | 1994 |
Chronic mild acidosis specifically reduces functional expression of N-methyl-D-aspartate receptors and increases long-term survival in primary cultures of cerebellar granule cells.
Topics: Acidosis; Animals; Cell Survival; Cells, Cultured; Cerebellum; Chronic Disease; Electrophysiology; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors | 1994 |
Chronic seizures increase glucose transporter abundance in rat brain.
Topics: Animals; Brain; Chronic Disease; Glucose Transporter Type 1; Glucose Transporter Type 3; Immunoblotting; Immunohistochemistry; Kainic Acid; Male; Monosaccharide Transport Proteins; Nerve Tissue Proteins; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Reference Values; Seizures; Time Factors | 1996 |
Enhanced NMDAR-dependent epileptiform activity is controlled by oxidizing agents in a chronic model of temporal lobe epilepsy.
Topics: Animals; Chronic Disease; Disease Models, Animal; Dithionitrobenzoic Acid; Electric Stimulation; Epilepsy, Temporal Lobe; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; Male; Oxidants; Oxidation-Reduction; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1996 |
Augmentation of nociceptive reflexes and chronic deafferentation pain by chemical lesions of either dopaminergic terminals or midbrain dopaminergic neurons.
Topics: Animals; Behavior, Animal; Chronic Disease; Denervation; Dopamine; Excitatory Amino Acid Agonists; Female; Kainic Acid; Ligation; Male; Microinjections; Neostriatum; Nerve Endings; Neurons; Nociceptors; Oxidopamine; Pain; Rats; Rats, Sprague-Dawley; Reflex; Sciatic Nerve; Substantia Nigra; Sympatholytics; Ventral Tegmental Area | 1997 |
Increased NR1-NR2A/B coassembly as a mechanism for rat chronic hippocampal epilepsy.
Topics: Animals; Chronic Disease; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1999 |
Immunohistochemical analysis on the role of adenosine A1 receptors in epilepsy.
Topics: Animals; Cell Count; CHO Cells; Chronic Disease; Cricetinae; Electrodes, Implanted; Epilepsy; Female; Hippocampus; Immunohistochemistry; Kainic Acid; Kindling, Neurologic; Male; Molecular Weight; Mossy Fibers, Hippocampal; Purinergic P1 Receptor Agonists; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Purinergic P1; Time Factors | 1999 |
Zinc in the extracellular area of the central nervous system is necessary for the development of kainic acid-induced persistent hyperalgesia in mice.
Topics: Aminoquinolines; Animals; Behavior, Animal; Cations, Divalent; Central Nervous System; Chelating Agents; Chronic Disease; Edetic Acid; Excitatory Amino Acid Agonists; Extracellular Space; Fluorescent Dyes; Hyperalgesia; Injections, Spinal; Kainic Acid; Male; Mice; Reaction Time; Tosyl Compounds; Zinc | 2000 |
Chronic epileptogenesis requires development of a network of pathologically interconnected neuron clusters: a hypothesis.
Topics: Action Potentials; Animals; Chronic Disease; Dentate Gyrus; Epilepsies, Partial; Epilepsy; Hippocampus; Kainic Acid; Kindling, Neurologic; Male; Models, Neurological; Neural Pathways; Neuronal Plasticity; Rats; Rats, Sprague-Dawley | 2000 |
NMDA receptor-dependent plasticity of granule cell spiking in the dentate gyrus of normal and epileptic rats.
Topics: Action Potentials; Animals; Chronic Disease; Dentate Gyrus; Electric Stimulation; Epilepsy; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Kainic Acid; Kindling, Neurologic; Magnesium; Male; Neuronal Plasticity; Neurons; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2000 |
Collapse of extracellular glutamate regulation during epileptogenesis: down-regulation and functional failure of glutamate transporter function in rats with chronic seizures induced by kainic acid.
Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Carrier Proteins; Chronic Disease; Dose-Response Relationship, Drug; Down-Regulation; Epilepsy; Extracellular Space; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Kainic Acid; Male; Membrane Proteins; Membrane Transport Proteins; Organic Anion Transporters; Potassium; Rats; Rats, Wistar; RNA, Messenger; Seizures | 2001 |
Changes in neuronal excitability and synaptic function in a chronic model of temporal lobe epilepsy.
Topics: Action Potentials; Animals; Chronic Disease; Epilepsy, Temporal Lobe; Excitatory Postsynaptic Potentials; Hippocampus; Kainic Acid; Long-Term Potentiation; Potassium Channel Blockers; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tetraethylammonium | 2001 |
Local generation of fast ripples in epileptic brain.
Topics: Action Potentials; Animals; Biological Clocks; Brain; Brain Mapping; Chronic Disease; Dentate Gyrus; Disease Models, Animal; Electric Stimulation; Entorhinal Cortex; Epilepsy; Evoked Potentials; Feedback; GABA Antagonists; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Microelectrodes; Neural Inhibition; Perforant Pathway; Rats; Rats, Sprague-Dawley; Reaction Time | 2002 |
Acromelic acid, a novel kainate analogue, induces long-lasting paraparesis with selective degeneration of interneurons in the rat spinal cord.
Topics: Animals; Behavior, Animal; Chronic Disease; Glial Fibrillary Acidic Protein; Immunohistochemistry; Interneurons; Kainic Acid; Male; Nerve Degeneration; Paraplegia; Rats; Rats, Inbred Strains; Spinal Cord | 1992 |
Alterations in cortical [3H]kainate and alpha-[3H]amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding in a spontaneous canine model of chronic hepatic encephalopathy.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Chronic Disease; Dizocilpine Maleate; Dogs; Glutamates; Glutamic Acid; Hepatic Encephalopathy; Ibotenic Acid; Kainic Acid; Ligands; Tritium | 1991 |
The contribution of non-NMDA and NMDA receptors to graded bursting activity in the CA1 region of the hippocampus in a chronic model of epilepsy.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Chronic Disease; Electric Stimulation; Electrophysiology; Epilepsy; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
[Regional cerebral blood flow during development of limbic seizures induced by kainic acid (KA) microinjection into unilateral amygdala in chronic cats].
Topics: Amygdala; Animals; Astrocytes; Cats; Cell Division; Cerebrovascular Circulation; Chronic Disease; Disease Models, Animal; Hippocampus; Hydrogen; Kainic Acid; Limbic System; Microinjections; Seizures | 1988 |