kainic acid has been researched along with Brain Injuries in 102 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.98) | 18.7374 |
| 1990's | 20 (19.61) | 18.2507 |
| 2000's | 59 (57.84) | 29.6817 |
| 2010's | 20 (19.61) | 24.3611 |
| 2020's | 2 (1.96) | 2.80 |
| Authors | Studies |
|---|---|
| Anagnostou, I; Morales, T; Muñoz-Mayorga, D | 1 |
| Aronica, E; Cattalini, A; de Curtis, M; Gnatkovsky, V; Pereira, MF; Testa, G; van Vliet, EA; Vila Verde, D; Zimmer, T | 1 |
| Dingledine, R; Du, Y; Jiang, J; Kinjo, ER; Nguyen, HP; Yu, Y | 1 |
| Alessi, C; Cattalini, A; Colciaghi, F; de Curtis, M; Figini, M; Noè, F; Vila Verde, D; Zucca, I | 1 |
| Caso, JR; Chien, BY; Hu, CK; Miguel, ZD; Munhoz, CD; Sapolsky, RM; Sorrells, SF; Tran, KV | 1 |
| Fahim, E; Friedman, LK; Halbsgut, LR; Hong, H; Kapoor, K | 1 |
| Brown, MS; Frey, L; Huber, K; Lepkin, A; Schickedanz, A; Serkova, N | 1 |
| Arkhipov, VI; Kapralova, MV | 1 |
| Choi, DJ; Choi, I; Jeong, HK; Ji, KM; Joe, EH; Jou, I; Min, KJ | 1 |
| Duncan, C; Gulland, FM; Kirkley, KS; Madl, JE; Tjalkens, RB | 1 |
| Bevinahal, PK; Bhonde, RR; Dhanushkodi, A; Rai, KS; Talakad, SN; Trichur, RR; Venugopal, C | 1 |
| Lei, GF; Li, BM; Li, J; Sun, RP; Wang, JW; Yin, P; Yu, L; Zhang, XT | 1 |
| Doihara, T; Hamada, F; Kobayashi, N; Matsuda, S; Nabeka, H; Saito, S; Shimokawa, T; Wakisaka, H | 1 |
| Agostinho, AS; Burtscher, J; Fogli, B; Hausott, B; Klimaschewski, L; Marvaldi, L; Schwarzer, C; Thongrong, S; Zangrandi, L | 1 |
| Baumann, M; Belluardo, N; Bruelle, C; Di Liberto, V; Eriksson, O; Korhonen, L; Lalowski, M; Lindholm, D; Louhivuori, L; Mäkelä, J; Mudò, G; Pham, DD; Soliymani, R | 1 |
| Andrade, P; Gröhn, O; Jokivarsi, K; Kettunen, MI; Leinonen, V; Paasonen, J; Pirttimäki, T; Pitkänen, A; Quittek, S; Salo, RA; Shatillo, A; Sierra, A | 1 |
| Darbar, A; Hodge, CJ; McCasland, JS; Siddiqui, AH; Stevens, RT | 1 |
| Gong, CX; Grundke-Iqbal, I; Iqbal, K; Liang, Z; Liu, F | 1 |
| Fawcett, JW; Raha-Chowdhury, R; Watts, C; Zhao, JW | 1 |
| Hatori, A; Inoue, O; Kawamura, K; Kumata, K; Odawara, C; Suzuki, K; Yamaguchi, M; Yamasaki, T; Yanamoto, K; Yui, J; Zhang, MR | 1 |
| Barresi, V; Belluardo, N; Condorelli, DF; Mudò, G; Trovato-Salinaro, A | 1 |
| Clark, S; Dudek, FE; Hellier, JL; Staley, KJ; White, A; Williams, PA | 1 |
| DellaValle, B; Hempel, C; Kurtzhals, JA; Penkowa, M | 1 |
| Azcoitia, I; Calvo, S; Cano, E; Martín, ED; Serrano-Pérez, MC; Tranque, P; Vaquero, CF | 1 |
| Banares, S; Hakem, R; Head, BP; Hu, Y; Huang, X; Krajewska, M; Krajewski, S; Kress, C; Kyoda, T; Leyva, R; Reed, JC; Rong, J; Salmena, L; Sze, CH; Whalen, MJ; Yang, J; You, Z | 1 |
| Chung, PW; Jin, DK; Kim, BJ; Kim, YB; Lee, SH; Lee, YT; Moon, HS; Park, KY; Park, YS; Suh, BC; Yoon, WT | 1 |
| Ambartsumian, N; Berezin, V; Bock, E; Dmytriyeva, O; Kiryushko, D; Lopez-Hoyos, M; Lukanidin, E; Marsolais, A; Owczarek, S; Pankratova, S; Ridley, CM; Sonn, K; Soroka, V | 1 |
| Doncarlos, LL; García-Ovejero, D; García-Segura, LM; Veiga, S | 1 |
| Alzheimer, C; Werner, S | 1 |
| Farooqui, AA; Fong, CW; Gopalakrishnakone, P; Kodama, K; Ong, WY; Sato, K; Thwin, MM | 1 |
| Bauer, K; Brauer, D; Christ, S; Friedrichsen, S; Heuer, H; Raivich, G; Winckler, M | 1 |
| Karbanová, J; Mokrý, J; Osterreicher, J | 1 |
| Al-Majdalawi, A; Calvo, B; Díaz-Flores, L; Garrosa, M; Gayoso, MJ | 1 |
| Giza, CC; Hovda, DA; Lee, SM; Vespa, PM; Zanier, ER | 1 |
| Farooqui, AA; Goh, EW; Halliwell, B; Lu, XR; Ong, WY; Patel, SC | 1 |
| Azcoitia, I; Garcia-Segura, LM; Hales, DB; Lavaque, E; Perez-Martin, M; Sierra, A | 1 |
| Cosi, C; Guerin, K; Koek, W; Marien, M; Rollet, K | 1 |
| Fukui, S; Ishihara, S; Nawashiro, H; Nomura, N; Otani, N; Shima, K; Tsuzuki, N | 1 |
| Anderson, PN; Bethea, JR; Burgaya, F; del Río, JA; Fontana, X; Hunt, D; Mingorance, A; Schwab, ME; Solé, M; Soriano, E; Tang, BL; Teng, FY; Ureña, JM | 1 |
| Hilton, GD; McCarthy, MM; Ndubuizu, AN | 1 |
| Adamo, EB; Altavilla, D; Bellomo, M; Bitto, A; Bonaccorso, MC; Calapai, G; Laureanti, F; Marini, H; Marini, R; Minutoli, L; Passaniti, M; Seminara, P; Squadrito, F | 1 |
| Culic, M; Filipovic, R; Milenkovic, I; Nedeljkovic, N; Pekovic, S; Rakic, L; Stojiljkovic, M | 1 |
| Atoji, Y; Wild, JM | 1 |
| Boring, L; Grass, DS; Hewitt, D; Purchio, AF; Ramboz, S; Zhu, L | 1 |
| Best, N; Gorianov, V; Nvue, R; Pringle, AK; Sundstrom, LE | 1 |
| Hattiangady, B; Rao, MS; Shetty, AK; Shetty, GA; Zaman, V | 1 |
| Liebkind, R; Liesi, P; Rauhala, P; Väänänen, A; Wiksten, M | 1 |
| Burns, KA; Davis, RJ; Flavell, RA; Kuan, CY; Lu, A; Rakic, P; Schloemer, AJ; Sharp, FR; Strauss, KI; Vorhees, CV; Weng, WL; Williams, MT | 1 |
| Chang, PY; Chao, CC; Kuo, JT; Lin-Chao, S | 1 |
| Behrens, A; Brecht, S; Chromik, A; Claussen, M; Davis, RJ; Flavell, RA; Goetz, M; Herdegen, T; Kirchhof, R; Kuan, CY; Nicolaus, T; Pearse, D; Raivich, G; Vaudano, E; Waetzig, V; Wagner, E; Wessig, J; Willesen, M | 1 |
| Alberch, J; Canals, JM; Canudas, AM; Pallàs, M; Pezzi, S | 1 |
| Cardoso, AL; da Cruz, MT; de Almeida, LP; de Lima, MC; Simões, S | 1 |
| Ampo, K; Kadono, C; Kiryu-Seo, S; Kiyama, H; Konishi, H; Maeda, M; Ohba, N | 1 |
| Antoniou, K; Kitraki, E; Papalexi, E | 1 |
| Chang, A; Cheng, H; Liao, LP; Lin, AM; Tsai, MJ; Wang, CH | 1 |
| Hilton, GD; McCarthy, MM; Ndubuizu, A; Nunez, JL | 1 |
| Clark, S; Dudek, FE; Ferraro, DJ; Kadam, SD; Staley, KJ; White, AM; Williams, PA | 1 |
| Janeczko, K; Nowak, B; Setkowicz, Z | 1 |
| Deschamps, K; Dubreuil, CI; Marklund, N; McIntosh, TK; McKerracher, L | 1 |
| Hattiangady, B; Rao, MS; Shetty, AK; Zaman, V | 1 |
| Ermakova, IV; Hodges, H; Loseva, EV; Sinden, J | 1 |
| Farooqui, AA; Horrocks, LA; Ong, WY | 1 |
| Cho, GJ; Choi, WS; Han, JY; Kang, AK; Kang, SS; Kim, YH; Kim, YS; Noh, HS; Park, CH; Shin, HS | 1 |
| Brenner, M; Fukui, S; Gomi, H; Nawashiro, H; Ohsumi, A; Ooigawa, H; Otani, N; Shima, K; Toyooka, T | 1 |
| Dai, F; Gu, PF; Hou, Y; Wu, CF; Yang, JY | 1 |
| Lacreuse, A; Mao, H; Toufexis, D; Wang, X; Wu, S | 1 |
| Rivest, S; Simard, AR | 1 |
| Cunningham, MO; Davies, CH; Driver, JE; LeBeau, FE; Racca, C; Towers, SK; Whittington, MA | 1 |
| Dudek, FE; Hellier, JL; Staley, KJ; White, AM; Williams, PA | 1 |
| Adem, A; Jin, T; Lu, MO; Mix, E; Quezada, HC; Zhang, XM; Zhu, J | 1 |
| Alvarez-Barrientos, A; Cortes-Canteli, M; Luna-Medina, R; Perez-Castillo, A; Santos, A; Sanz-Sancristobal, M | 1 |
| Barbin, G; Cotman, CW; Manthrope, M; Nieto-Sampedro, M; Varon, S | 1 |
| Bell, MD; Fraser, I; Gordon, S; Hughes, D; Lawson, L; Lopez-Gonzalez, R; Perry, VH | 1 |
| Le Gal La Salle, G; Ridoux, V; Synguelakis, M; Valin, A | 1 |
| Ibáñez, CF; Persson, H | 1 |
| Baldwin, SA; Cheng, B; Christakos, S; Geddes, JW; Keller, J; Mattson, MP; Scheff, SW; Smith-Swintosky, VL | 1 |
| Araujo, M; Wandosell, F | 1 |
| Panter, SS; Regan, RF | 1 |
| Alzheimer, C; Hübner, G; Munz, B; ten Bruggencate, G; Tretter, YP; Werner, S | 1 |
| Gallyas, F; Ribak, CE; Séress, L; Tóth, P; Tóth, Z | 1 |
| Bausch, SB; Catterall, WA; Franck, JE; Lin, RC; Noebels, JL; Westenbroek, RE | 1 |
| Kelly, JB; van Adel, BA | 1 |
| Der Terrossian, E; Plantier, M; Represa, A | 1 |
| Faddis, BT; Goldberg, MP; Hasbani, MJ; Hyrc, KL; Romano, C | 1 |
| Azcoitia, I; Garcia-Segura, LM; Hutchison, JB; Hutchison, RE; Rodriguez, JR; Wozniak, A | 1 |
| He, X; Shiosaka, S; Tomizawa, K; Yamanaka, H; Yoshida, S | 1 |
| Aguado, F; Ferrer, I; Pozas, E | 1 |
| Alzheimer, C; Hertel, M; Tretter, Y; Werner, S | 1 |
| Carbonell, WS; Grady, MS | 1 |
| Agnello, D; Brines, ML; Cerami, A; Cerami, C; de Lanerolle, NC; Ghezzi, P; Itri, LM; Keenan, S | 1 |
| Bing, G; Feng, Z; Han, Y; Hong, J; Iadarola, M; Qi, Q; Tiao, N; Wilson, B | 1 |
| He, XP; Shiosaka, S; Yoshida, S | 1 |
| Corti, C; Ferraguti, F; Mion, S; Valerio, E; Xuereb, J | 1 |
| Giuli, LC; Kunis, D; Meier, TJ; Monje, ML; Phillips, RG; Sapolsky, RM; Yenari, MA | 1 |
| Benz, AM; Izumi, M; Izumi, Y; Zorumski, CF | 1 |
| Baldinotti, I; Ciani, E; Contestabile, A | 1 |
| Chabot, JG; Mennicken, F; Quirion, R | 1 |
| Aono, S; Kawashima, S; Keino, H; Matsui, F; Oohira, A; Shuo, T; Tokita, Y; Yamauchi, S | 1 |
| Dahlström, A; Ling, EA; McRae, A; Nee, LE; Polinsky, RJ | 1 |
| Clifton, GL; Dixon, CE; Hamm, RJ; Hayes, RL; Jenkins, LW; Lyeth, BG; Miller, LP; Oleniak, L; Panchision, D; Phillips, LL | 1 |
| Brown, IR | 1 |
| Cooley, RK; Fine, A; Vanderwolf, CH | 1 |
5 review(s) available for kainic acid and Brain Injuries
| Article | Year |
|---|---|
Fibroblast growth factors and neuroprotection.
Topics: Activins; Animals; Apoptosis; Brain; Brain Injuries; Calcium; Fibroblast Growth Factors; Humans; Inhibin-beta Subunits; Kainic Acid; Mitochondria; Multigene Family; Neuroglia; Neurons; Neuroprotective Agents; Reactive Oxygen Species; Receptors, Fibroblast Growth Factor; Receptors, Kainic Acid | 2002 |
Inhibitors of brain phospholipase A2 activity: their neuropharmacological effects and therapeutic importance for the treatment of neurologic disorders.
Topics: Animals; Blood Proteins; Brain; Brain Injuries; Humans; Kainic Acid; Models, Biological; Nervous System Diseases; Neurons; Pain; Phospholipases A; Phospholipases A2 | 2006 |
Development of spontaneous seizures after experimental status epilepticus: implications for understanding epileptogenesis.
Topics: Animals; Biomarkers; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Humans; Kainic Acid; Models, Neurological; Monitoring, Physiologic; Rats; Seizures; Status Epilepticus; Telemetry; Time Factors; Videotape Recording | 2007 |
Role and expression of neurotrophins and the trk family of tyrosine kinase receptors in neural growth and rescue after injury.
Topics: Animals; Base Sequence; Brain Injuries; Central Nervous System; Cloning, Molecular; Female; Fibroblasts; Hippocampus; Humans; In Situ Hybridization; Kainic Acid; Male; Molecular Sequence Data; Neuropeptides; Protein-Tyrosine Kinases; Receptors, Nerve Growth Factor; RNA, Messenger; Signal Transduction | 1993 |
Induction of heat shock (stress) genes in the mammalian brain by hyperthermia and other traumatic events: a current perspective.
Topics: Animals; Brain Chemistry; Brain Injuries; Brain Ischemia; Fever; Gene Expression Regulation; Heat-Shock Proteins; Humans; Infections; Kainic Acid; Mammals; Multigene Family; Nerve Tissue Proteins; Rabbits; Rats; Seizures | 1990 |
97 other study(ies) available for kainic acid and Brain Injuries
| Article | Year |
|---|---|
Prolactin neuroprotective action against excitotoxic insult in the hippocampus of male mice.
Topics: Animals; Brain Injuries; Cell Death; Disease Models, Animal; Hippocampus; Humans; Kainic Acid; Mice; Neurons; Neuroprotective Agents; Neurotoxins; Prolactin; Rats | 2021 |
Seizure activity and brain damage in a model of focal non-convulsive status epilepticus.
Topics: Animals; Anticonvulsants; Brain; Brain Injuries; Disease Models, Animal; Epilepsy; Guinea Pigs; Kainic Acid; Seizures; Status Epilepticus | 2021 |
Suppressing pro-inflammatory prostaglandin signaling attenuates excitotoxicity-associated neuronal inflammation and injury.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Injuries; Cytokines; Dinoprostone; Disease Models, Animal; Gliosis; Hippocampus; Indoles; Inflammation; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Receptors, Prostaglandin E, EP2 Subtype; Seizures; Signal Transduction; Status Epilepticus | 2019 |
Epileptiform activity contralateral to unilateral hippocampal sclerosis does not cause the expression of brain damage markers.
Topics: Animals; Biomarkers; Brain Injuries; CA1 Region, Hippocampal; Electroencephalography; Epilepsy; Excitatory Amino Acid Agonists; Guinea Pigs; Hippocampus; Kainic Acid; Magnetic Resonance Imaging; Male; Nerve Tissue Proteins; Sclerosis; Status Epilepticus | 2019 |
Glucocorticoid signaling in myeloid cells worsens acute CNS injury and inflammation.
Topics: Analysis of Variance; Animals; Brain Infarction; Brain Injuries; Brain-Derived Neurotrophic Factor; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Corticosterone; Cytokines; Disease Models, Animal; Encephalitis; Gene Expression Regulation; Green Fluorescent Proteins; Infarction, Middle Cerebral Artery; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microfilament Proteins; Myeloid Cells; NF-kappaB-Inducing Kinase; Protein Serine-Threonine Kinases; Receptor Protein-Tyrosine Kinases; Receptor, TIE-2; Receptors, Glucocorticoid; Signal Transduction | 2013 |
Certain secondary antiepileptic drugs can rescue hippocampal injury following a critical growth period despite poor anticonvulsant activity and cognitive deficits.
Topics: Age Factors; Animals; Animals, Newborn; Anticonvulsants; Body Weight; Brain Injuries; Cell Count; Cognition Disorders; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Hippocampus; Humans; Kainic Acid; Male; Maze Learning; Rats; Rats, Sprague-Dawley; Seizures; Treatment Outcome | 2013 |
ADC mapping and T1-weighted signal changes on post-injury MRI predict seizure susceptibility after experimental traumatic brain injury.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries; Convulsants; Diffusion Magnetic Resonance Imaging; Electroencephalography; Epilepsy, Post-Traumatic; Kainic Acid; Magnetic Resonance Imaging; Male; Prognosis; Rats; Rats, Sprague-Dawley; Seizures; Severity of Illness Index; Time Factors | 2014 |
Expression of metabotropic glutamate receptors after hippocampal injury.
Topics: Animals; Brain Injuries; CA3 Region, Hippocampal; Frontal Lobe; Gene Expression; Kainic Acid; Male; Rats, Wistar; Receptors, Metabotropic Glutamate; RNA, Long Noncoding; Synaptic Transmission | 2014 |
Astrogliosis is a possible player in preventing delayed neuronal death.
Topics: Animals; Astrocytes; Biomarkers; Brain Injuries; Cell Communication; Cell Death; Cerebral Cortex; Excitatory Amino Acid Transporter 2; Glial Fibrillary Acidic Protein; Gliosis; Glutamate-Ammonia Ligase; Kainic Acid; Male; N-Methylaspartate; Neurons; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; S100 Calcium Binding Protein beta Subunit | 2014 |
Domoic acid-induced seizures in California sea lions (Zalophus californianus) are associated with neuroinflammatory brain injury.
Topics: Animals; Brain Injuries; Glutamate-Ammonia Ligase; Kainic Acid; Neurons; Oxidative Stress; Sea Lions; Seizures; Water Pollutants, Chemical | 2014 |
Infusion of human embryonic kidney cell line conditioned medium reverses kainic acid induced hippocampal damage in mice.
Topics: Animals; Brain Injuries; Culture Media, Conditioned; Excitatory Amino Acid Agonists; HEK293 Cells; Hippocampus; Humans; Kainic Acid; Male; Mice; Time Factors | 2014 |
Maternal immune activation increases seizure susceptibility in juvenile rat offspring.
Topics: Animals; Animals, Newborn; Anxiety; Brain Injuries; Disease Models, Animal; Disease Susceptibility; Epilepsy; Female; Hippocampus; Kainic Acid; Lipopolysaccharides; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Seizures | 2015 |
A prosaposin-derived Peptide alleviates kainic Acid-induced brain injury.
Topics: Amino Acid Sequence; Animals; Avoidance Learning; Brain Injuries; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Molecular Sequence Data; Nerve Growth Factors; Neurons; Peptide Fragments; Rats; Rats, Wistar; Saposins; Synapses | 2015 |
Sprouty2 and -4 hypomorphism promotes neuronal survival and astrocytosis in a mouse model of kainic acid induced neuronal damage.
Topics: Analysis of Variance; Animals; Brain Injuries; Cell Survival; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Gene Expression Regulation; Gliosis; Hippocampus; Intracellular Signaling Peptides and Proteins; Kainic Acid; Male; Membrane Proteins; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Pentylenetetrazole; Protein Serine-Threonine Kinases; RNA, Messenger; Seizures; Signal Transduction | 2016 |
Peroxisome proliferator-activated receptor-γ coactivator-1α mediates neuroprotection against excitotoxic brain injury in transgenic mice: role of mitochondria and X-linked inhibitor of apoptosis protein.
Topics: Animals; bcl-X Protein; Brain Injuries; CA1 Region, Hippocampal; Cell Death; Cells, Cultured; Inhibitor of Apoptosis Proteins; Kainic Acid; Mice; Mitochondria; Neurons; Oxidative Phosphorylation; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Proto-Oncogene Proteins c-bcl-2 | 2016 |
Implantable RF-coil with multiple electrodes for long-term EEG-fMRI monitoring in rodents.
Topics: Animals; Brain; Brain Injuries; Brain Mapping; Electrodes, Implanted; Electroencephalography; Evoked Potentials, Somatosensory; Excitatory Amino Acid Agonists; Follow-Up Studies; Image Processing, Computer-Assisted; Kainic Acid; Magnetic Resonance Imaging; Male; Monitoring, Physiologic; Oxygen; Rats; Rats, Wistar; Signal-To-Noise Ratio | 2016 |
Pharmacological modulation of cortical plasticity following kainic acid lesion in rat barrel cortex.
Topics: Animals; Anticonvulsants; Brain Injuries; Central Nervous System Stimulants; Cerebral Cortex; Dextroamphetamine; Kainic Acid; Neuronal Plasticity; Phenytoin; Rats; Rats, Sprague-Dawley; Recovery of Function; Time Factors; Vibrissae | 2008 |
Dysregulation of tau phosphorylation in mouse brain during excitotoxic damage.
Topics: Animals; Brain Injuries; Excitatory Amino Acid Agonists; Gene Expression Regulation; Glycogen Synthase Kinase 3; Immunoprecipitation; Kainic Acid; Male; Mice; Phosphorylation; Protein Phosphatase 2; Protein Subunits; tau Proteins; Time Factors | 2009 |
Astrocytes and oligodendrocytes can be generated from NG2+ progenitors after acute brain injury: intracellular localization of oligodendrocyte transcription factor 2 is associated with their fate choice.
Topics: Animals; Antigens; Astrocytes; Basic Helix-Loop-Helix Transcription Factors; Brain Injuries; Cell Nucleus; Cell Proliferation; Cytoplasm; Encephalitis; Female; Glial Fibrillary Acidic Protein; Kainic Acid; Lipopolysaccharides; Male; Mice; Nerve Tissue Proteins; Oligodendrocyte Transcription Factor 2; Oligodendroglia; Proteoglycans; Random Allocation; Rats; Rats, Sprague-Dawley; Seizures; Stem Cells | 2009 |
Evaluation of N-benzyl-N-[11C]methyl-2- (7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide ([11C]DAC) as a novel translocator protein (18 kDa) radioligand in kainic acid-lesioned rat.
Topics: Animals; Brain Injuries; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Excitatory Amino Acid Agonists; Kainic Acid; Ligands; Male; Mice; Positron-Emission Tomography; Purines; Radioligand Assay; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, GABA; Tissue Distribution | 2009 |
Identification of calcium sensing receptor (CaSR) mRNA-expressing cells in normal and injured rat brain.
Topics: Animals; Brain; Brain Injuries; Cell Count; Ibotenic Acid; Immunohistochemistry; In Situ Hybridization; Kainic Acid; Male; Neurons; Oligodendroglia; Rats; Rats, Wistar; Receptors, Calcium-Sensing; RNA, Messenger; Seizures; Time Factors | 2009 |
EEG spike activity precedes epilepsy after kainate-induced status epilepticus.
Topics: Action Potentials; Animals; Biomarkers; Brain Injuries; Chronic Disease; Dentate Gyrus; Disease Models, Animal; Electroencephalography; Epilepsy; Humans; Kainic Acid; Male; Monitoring, Physiologic; Rats; Rats, Sprague-Dawley; Recurrence; Signal Processing, Computer-Assisted; Status Epilepticus; Telemetry; Time Factors; Video Recording | 2010 |
In vivo expression of neuroglobin in reactive astrocytes during neuropathology in murine models of traumatic brain injury, cerebral malaria, and autoimmune encephalitis.
Topics: Animals; Astrocytes; Autoimmune Diseases of the Nervous System; Brain; Brain Injuries; Disease Models, Animal; Encephalitis; Epilepsy; Female; Globins; Immunohistochemistry; Kainic Acid; Malaria, Cerebral; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuroglobin; Neurons | 2010 |
Response of transcription factor NFATc3 to excitotoxic and traumatic brain insults: identification of a subpopulation of reactive astrocytes.
Topics: Analysis of Variance; Animals; Astrocytes; Blotting, Western; Brain; Brain Injuries; Cell Death; Glial Fibrillary Acidic Protein; Immunohistochemistry; Kainic Acid; Mice; Microscopy, Confocal; Neurons; NFATC Transcription Factors; Reverse Transcriptase Polymerase Chain Reaction | 2011 |
Neuronal deletion of caspase 8 protects against brain injury in mouse models of controlled cortical impact and kainic acid-induced excitotoxicity.
Topics: Animals; Blood-Brain Barrier; Brain Injuries; Caspase 8; Cell Death; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Gene Deletion; Gliosis; Inflammation; Kainic Acid; Memory; Mice; Neurons; Neurotoxins; Seizures; Tumor Necrosis Factor-alpha | 2011 |
IL-1β induction and IL-6 suppression are associated with aggravated neuronal damage in a lipopolysaccharide-pretreated kainic acid-induced rat pup seizure model.
Topics: Animals; Animals, Newborn; Body Temperature; Brain Injuries; Cytokines; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Hippocampus; Interleukin-1beta; Interleukin-6; Kainic Acid; Lipopolysaccharides; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reaction Time; Seizures; Statistics, Nonparametric; Status Epilepticus; Time Factors; Tumor Necrosis Factor-alpha | 2012 |
The metastasis-promoting S100A4 protein confers neuroprotection in brain injury.
Topics: Amino Acid Motifs; Animals; Brain Injuries; Cell Death; Cytoprotection; Female; Gene Deletion; HEK293 Cells; Humans; Janus Kinases; Kainic Acid; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neurons; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Peptides; Rats; Receptors, Interleukin-10; S100 Calcium-Binding Protein A4; S100 Proteins; Seizures; STAT Transcription Factors; Up-Regulation | 2012 |
Glial expression of estrogen and androgen receptors after rat brain injury.
Topics: Animals; Astrocytes; Brain; Brain Injuries; Disease Models, Animal; Estrogen Receptor alpha; Estrogen Receptor beta; Glial Fibrillary Acidic Protein; Gliosis; Immunohistochemistry; Kainic Acid; Lectins; Male; Microglia; Nerve Degeneration; Nerve Regeneration; Neuroglia; Plant Lectins; Rats; Rats, Wistar; Receptors, Androgen; Receptors, Estrogen; Vimentin | 2002 |
Secretory phospholipase A2 activity in the normal and kainate injected rat brain, and inhibition by a peptide derived from python serum.
Topics: Amino Acid Sequence; Animals; Boidae; Brain; Brain Injuries; Excitatory Amino Acid Agonists; Hippocampus; Injections, Intraventricular; Kainic Acid; Medulla Oblongata; Molecular Sequence Data; Neurotoxins; Peptides; Phospholipases A; Phospholipases A2; Pons; Rats; Rats, Wistar | 2003 |
Connective tissue growth factor: a novel marker of layer VII neurons in the rat cerebral cortex.
Topics: Animals; Animals, Newborn; Biomarkers; Brain Injuries; Cerebral Cortex; Connective Tissue Growth Factor; Embryo, Mammalian; Excitatory Amino Acid Agonists; Female; Gene Expression Regulation, Developmental; Hippocampus; Immediate-Early Proteins; In Situ Hybridization; Intercellular Signaling Peptides and Proteins; Kainic Acid; Male; Mice; Microtubule-Associated Proteins; Neurons; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA Probes; RNA, Messenger; Sulfur Isotopes; Time Factors | 2003 |
Experimental brain injury induces activation of neural stem cells in the forebrain subependyma.
Topics: Animals; Brain Injuries; Cell Division; Cyclophosphamide; Female; Immunophenotyping; Kainic Acid; Neurons; Nitroprusside; Prosencephalon; Rats; Rats, Wistar; Stem Cells; Time Factors | 2003 |
Selective calcification of rat brain lesions caused by systemic administration of kainic acid.
Topics: Animals; Astrocytes; Brain; Brain Injuries; Calcium; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Kainic Acid; Lectins; Male; Microglia; Neurons; Rats; Rats, Wistar; Time Factors | 2003 |
Increased hippocampal CA3 vulnerability to low-level kainic acid following lateral fluid percussion injury.
Topics: Animals; Blood-Brain Barrier; Brain Injuries; Cell Count; Excitatory Amino Acid Agonists; Functional Laterality; Glucose; Hippocampus; Kainic Acid; Male; Neurons; Rats; Rats, Sprague-Dawley; Seizures | 2003 |
Increase in cholesterol and cholesterol oxidation products, and role of cholesterol oxidation products in kainate-induced neuronal injury.
Topics: Animals; Animals, Newborn; Brain Injuries; Cholesterol; Ethanol; Excitatory Amino Acid Agonists; Gas Chromatography-Mass Spectrometry; Hippocampus; Immunohistochemistry; In Vitro Techniques; Kainic Acid; Microscopy, Electron; Oxidation-Reduction; Rats; Rats, Wistar; Receptors, AMPA | 2003 |
Steroidogenic acute regulatory protein in the rat brain: cellular distribution, developmental regulation and overexpression after injury.
Topics: Aging; Animals; Animals, Newborn; Brain Chemistry; Brain Injuries; Bromodeoxyuridine; Excitatory Amino Acid Agonists; Gene Expression Regulation, Developmental; Immunohistochemistry; Kainic Acid; Male; Neurons; Phosphoproteins; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2003 |
The PARP inhibitor benzamide protects against kainate and NMDA but not AMPA lesioning of the mouse striatum in vivo.
Topics: Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzamides; Brain Injuries; Chromatography, High Pressure Liquid; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Time Factors | 2004 |
A role of glial fibrillary acidic protein in hippocampal degeneration after cerebral trauma or kainate-induced seizure.
Topics: Animals; Brain Injuries; Cell Survival; Glial Fibrillary Acidic Protein; Hippocampus; Kainic Acid; Mice; Mice, Knockout; Nerve Degeneration; Neurons; Seizures; Wounds, Nonpenetrating | 2003 |
Regulation of Nogo and Nogo receptor during the development of the entorhino-hippocampal pathway and after adult hippocampal lesions.
Topics: Animals; Animals, Newborn; Antibodies; Astrocytes; Brain Injuries; COS Cells; Entorhinal Cortex; Fetus; Gene Expression Regulation, Developmental; Gliosis; GPI-Linked Proteins; Growth Cones; Hippocampus; Kainic Acid; Mice; Myelin Proteins; Nerve Regeneration; Neuronal Plasticity; Nogo Proteins; Nogo Receptor 1; Perforant Pathway; Receptors, Cell Surface; Receptors, Peptide; RNA, Messenger | 2004 |
Neuroprotective effects of estradiol in newborn female rat hippocampus.
Topics: Analysis of Variance; Animals; Animals, Newborn; Brain Injuries; Cell Count; Cell Death; Cells, Cultured; Drug Interactions; Estradiol; Estrogen Antagonists; Female; Hippocampus; Kainic Acid; L-Lactate Dehydrogenase; Neuroprotective Agents; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Tamoxifen; Time Factors | 2004 |
Modulation of IL-1 beta gene expression by lipid peroxidation inhibition after kainic acid-induced rat brain injury.
Topics: Animals; Behavior, Animal; Benzofurans; Brain Edema; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Gene Expression Regulation; Glutathione; Hippocampus; Interleukin-1; Kainic Acid; Lipid Peroxidation; Male; Malondialdehyde; Nerve Degeneration; Neurotoxins; Oxidative Stress; Rats; Rats, Sprague-Dawley; RNA, Messenger; Seizures | 2004 |
Spatio-temporal changes in neurofilament proteins immunoreactivity following kainate-induced cerebellar lesion in rats.
Topics: Animals; Brain Injuries; Cerebellum; Disease Models, Animal; Glutamic Acid; Immunohistochemistry; Kainic Acid; Male; Nerve Fibers, Myelinated; Nerve Regeneration; Neurofilament Proteins; Neuronal Plasticity; Neurons; Neurotoxins; Purkinje Cells; Rats; Rats, Wistar; Reaction Time; Synaptophysin; Up-Regulation | 2004 |
Fiber connections of the hippocampal formation and septum and subdivisions of the hippocampal formation in the pigeon as revealed by tract tracing and kainic acid lesions.
Topics: Animals; Biotin; Brain Injuries; Cholera Toxin; Columbidae; Dextrans; Female; Hippocampus; Histocytochemistry; Kainic Acid; Male; Nerve Fibers; Neural Networks, Computer; Neural Pathways; Neurons; Septum of Brain | 2004 |
Non-invasive imaging of GFAP expression after neuronal damage in mice.
Topics: Animals; Brain Injuries; Brain Mapping; Diagnostic Imaging; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Kainic Acid; Liver; Luciferases; Mice; Mice, Transgenic; Neurons; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staining and Labeling; Time Factors | 2004 |
Time window and pharmacological characterisation of kainate-mediated preconditioning in organotypic rat hippocampal slice cultures.
Topics: Animals; Animals, Newborn; Brain Injuries; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Organ Culture Techniques; Quinoxalines; Rats; Rats, Wistar; Time Factors | 2004 |
Hippocampal neurotrophin levels after injury: Relationship to the age of the hippocampus at the time of injury.
Topics: Aging; Animals; Behavior, Animal; Brain Chemistry; Brain Injuries; CD11b Antigen; Cell Count; Enzyme-Linked Immunosorbent Assay; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Injections, Intraventricular; Kainic Acid; Male; Nerve Growth Factors; Rats; Rats, Inbred F344 | 2004 |
Soluble KDI domain of gamma1 laminin protects adult hippocampus from excitotoxicity of kainic acid.
Topics: Animals; Brain Injuries; Drug Interactions; Functional Laterality; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Kainic Acid; Laminin; Male; Neocortex; Protein Structure, Tertiary; Rats; Rats, Wistar; Staining and Labeling; Stereotaxic Techniques | 2004 |
Hypoxia-ischemia induces DNA synthesis without cell proliferation in dying neurons in adult rodent brain.
Topics: Adrenalectomy; Age Factors; Animals; Apoptosis; Brain; Brain Injuries; Bromodeoxyuridine; DNA; Excitatory Amino Acid Agonists; Hippocampus; Hypoxia-Ischemia, Brain; In Situ Nick-End Labeling; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Neurons; Rats; Rats, Sprague-Dawley; S Phase | 2004 |
Identification of rat Gas7 isoforms differentially expressed in brain and regulated following kainate-induced neuronal injury.
Topics: Amino Acid Sequence; Animals; Blotting, Northern; Blotting, Western; Brain Injuries; Cloning, Molecular; Excitatory Amino Acid Agonists; Gene Expression Regulation; Immunohistochemistry; Kainic Acid; Male; Mice; Molecular Sequence Data; Nerve Tissue Proteins; Neurites; PC12 Cells; Protein Isoforms; Rats; Rats, Sprague-Dawley; RNA; Sequence Alignment; Time Factors; Transfection | 2005 |
Specific pathophysiological functions of JNK isoforms in the brain.
Topics: Animals; Autonomic Denervation; Behavior, Animal; Blotting, Western; Brain; Brain Injuries; Cell Count; Cell Death; Enzyme Activation; Facial Nerve Diseases; Female; Functional Laterality; Gene Expression Regulation; Immunohistochemistry; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Isoenzymes; Kainic Acid; Male; Medial Forebrain Bundle; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neurons; Oxidopamine; Phosphorylation; Proto-Oncogene Proteins c-jun; Serine; Staining and Labeling; Time Factors; Tyrosine 3-Monooxygenase | 2005 |
Endogenous brain-derived neurotrophic factor protects dopaminergic nigral neurons against transneuronal degeneration induced by striatal excitotoxic injury.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Blotting, Northern; Brain Injuries; Brain-Derived Neurotrophic Factor; Cell Count; Corpus Striatum; Diagnostic Imaging; Dopamine; Electrophoretic Mobility Shift Assay; Functional Laterality; Gene Expression Regulation, Developmental; Immunoglobulin G; Immunohistochemistry; In Situ Hybridization; Kainic Acid; Male; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Receptor, trkB; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2005 |
Tf-lipoplex-mediated NGF gene transfer to the CNS: neuronal protection and recovery in an excitotoxic model of brain injury.
Topics: Animals; Brain; Brain Chemistry; Brain Injuries; Corpus Striatum; Gene Expression; Genetic Therapy; Immunohistochemistry; Injections; Kainic Acid; Liposomes; Male; Models, Animal; Nerve Growth Factor; Rats; Rats, Wistar; Transfection; Transferrin | 2005 |
The p53-independent nuclear translocation of cyclin G1 in degenerating neurons by ischemic and traumatic insults.
Topics: Animals; Brain Injuries; Brain Ischemia; Cell Death; Cells, Cultured; Cyclin G; Cyclin G1; Cyclins; Cycloheximide; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Fluoresceins; Fluorescent Dyes; Gene Expression Regulation; Gerbillinae; Immunohistochemistry; In Situ Hybridization; In Situ Nick-End Labeling; Kainic Acid; Mice; Mice, Knockout; Microscopy, Immunoelectron; N-Methylaspartate; Nerve Degeneration; Neurons; Organic Chemicals; Phosphopyruvate Hydratase; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Time Factors; Tumor Suppressor Protein p53 | 2005 |
Estrogens influence behavioral responses in a kainic acid model of neurotoxicity.
Topics: Analysis of Variance; Animals; Brain Injuries; Estradiol; Exploratory Behavior; Female; Hippocampus; Kainic Acid; Maze Learning; Models, Animal; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; Ovariectomy; Rats; Rats, Wistar; Recognition, Psychology; Space Perception | 2005 |
Kainic acid-induced oxidative injury is attenuated by hypoxic preconditioning.
Topics: Animals; Antioxidants; Apoptosis; Brain; Brain Injuries; Female; Hematocrit; Hypoxia; Kainic Acid; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred WKY | 2005 |
Simultaneous glutamate and GABA(A) receptor agonist administration increases calbindin levels and prevents hippocampal damage induced by either agent alone in a model of perinatal brain injury.
Topics: Animals; Animals, Newborn; Blotting, Western; Brain Injuries; Calbindins; Cells, Cultured; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Agonists; GABA Agonists; Hippocampus; Immunohistochemistry; Kainic Acid; Muscimol; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; S100 Calcium Binding Protein G | 2005 |
Efficient unsupervised algorithms for the detection of seizures in continuous EEG recordings from rats after brain injury.
Topics: Algorithms; Animals; Artifacts; Brain Injuries; Electroencephalography; Hippocampus; Kainic Acid; Models, Statistical; Predictive Value of Tests; Rats; Seizures; Telemetry | 2006 |
Neocortical injuries at different developmental stages determine different susceptibility to seizures induced in adulthood.
Topics: Animals; Brain; Brain Injuries; Convulsants; Kainic Acid; Kindling, Neurologic; Male; Neocortex; Rats; Rats, Wistar; Status Epilepticus | 2006 |
Activation of Rho after traumatic brain injury and seizure in rats.
Topics: Animals; Anticonvulsants; Brain Injuries; Cerebral Cortex; Diazepam; Disease Models, Animal; Drug Interactions; Enzyme Activation; Gene Expression Regulation, Enzymologic; Hippocampus; Kainic Acid; Male; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; Seizures | 2006 |
Incorporation of embryonic CA3 cell grafts into the adult hippocampus at 4-months after injury: effects of combined neurotrophic supplementation and caspase inhibition.
Topics: Animals; Brain Injuries; Bromodeoxyuridine; Caspases; Cell Count; Cell Survival; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hippocampus; Histocytochemistry; Kainic Acid; Male; Nerve Growth Factors; Neurons; Phosphopyruvate Hydratase; Rats; Rats, Inbred F344; Stem Cell Transplantation | 2006 |
Transplantation of cultured astrocytes attenuates degenerative changes in rats with kainic acid-induced brain damage.
Topics: Amygdala; Animals; Antibodies, Monoclonal; Astrocytes; Brain; Brain Injuries; Cell Transplantation; Cells, Cultured; Dentate Gyrus; Hippocampus; Kainic Acid; Male; Rats; Rats, Wistar | 2005 |
Ketogenic diet protects the hippocampus from kainic acid toxicity by inhibiting the dissociation of bad from 14-3-3.
Topics: 14-3-3 Proteins; Animals; bcl-Associated Death Protein; Blotting, Western; Brain Injuries; Caspase 3; Diet, Carbohydrate-Restricted; Gene Expression Regulation; Hippocampus; Immunoprecipitation; Kainic Acid; Male; Mice; Mice, Inbred ICR | 2006 |
Enhanced hippocampal neurodegeneration after traumatic or kainate excitotoxicity in GFAP-null mice.
Topics: Animals; Astrocytes; Brain Injuries; Cell Communication; Cell Survival; Cytoprotection; Disease Models, Animal; Drug Resistance; Glial Fibrillary Acidic Protein; Hippocampus; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Neurotoxins; Pyramidal Cells; Recovery of Function; Seizures; Up-Regulation | 2006 |
Effect of drug-induced ascorbic acid release in the striatum and the nucleus accumbens in hippocampus-lesioned rats.
Topics: Analysis of Variance; Animals; Ascorbic Acid; Brain Chemistry; Brain Injuries; Central Nervous System Depressants; Central Nervous System Stimulants; Corpus Striatum; Ethanol; Hippocampus; Interneurons; Kainic Acid; Male; Methamphetamine; Microdialysis; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Rats; Rats, Wistar | 2006 |
Changes of metabolite profile in kainic acid induced hippocampal injury in rats measured by HRMAS NMR.
Topics: Amino Acids; Animals; Brain Injuries; Excitatory Amino Acid Agonists; Excitatory Amino Acids; gamma-Aminobutyric Acid; Hippocampus; Kainic Acid; Magnetic Resonance Spectroscopy; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 2007 |
Neuroprotective effects of resident microglia following acute brain injury.
Topics: Animals; Bone Marrow Transplantation; Brain Injuries; Disease Models, Animal; Glucocorticoids; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Myeloid Differentiation Factor 88; NF-kappa B; Nitroprusside; Stilbamidines; Thymidine Kinase; Time Factors | 2007 |
Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP).
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Age Factors; Amyloid beta-Protein Precursor; Animals; Biological Clocks; Brain Injuries; Calcium Channel Agonists; Dose-Response Relationship, Drug; Drug Interactions; Hippocampus; Humans; In Vitro Techniques; Kainic Acid; Mice; Mice, Transgenic; Spectrum Analysis | 2007 |
TNF-alpha receptor 1 deficiency enhances kainic acid-induced hippocampal injury in mice.
Topics: Animals; Behavior, Animal; Brain Injuries; Case-Control Studies; CD11b Antigen; Exploratory Behavior; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hippocampus; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Motor Activity; Neurodegenerative Diseases; Receptors, Tumor Necrosis Factor, Type I; Seizures | 2008 |
CCAAT/enhancer binding protein beta deficiency provides cerebral protection following excitotoxic injury.
Topics: Animals; Brain Injuries; CCAAT-Enhancer-Binding Protein-beta; Cells, Cultured; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Mice; Rats | 2008 |
Injury-induced neuronotrophic activity in adult rat brain: correlation with survival of delayed implants in the wound cavity.
Topics: Animals; Brain Injuries; Corpus Striatum; Graft Survival; Kainic Acid; Male; Neurons; Rats; Rats, Inbred Strains | 1983 |
Upregulation of the macrophage scavenger receptor in response to different forms of injury in the CNS.
Topics: Animals; Animals, Newborn; Antibodies, Monoclonal; Brain; Brain Injuries; Immunohistochemistry; Kainic Acid; Lipopolysaccharides; Macrophages; Membrane Proteins; Mice; Mice, Inbred BALB C; Nerve Crush; Optic Nerve; Optic Nerve Injuries; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Reference Values; Scavenger Receptors, Class B; Sciatic Nerve; Up-Regulation | 1994 |
Ex vivo culture of adult microglial cells from previously lesioned rat brains.
Topics: Animals; Astrocytes; Brain Injuries; Cell Division; Cells, Cultured; Hippocampus; Kainic Acid; Male; Microglia; Rats; Rats, Wistar | 1994 |
Brain injury and tumor necrosis factors induce calbindin D-28k in astrocytes: evidence for a cytoprotective response.
Topics: Animals; Astrocytes; Blotting, Western; Brain Injuries; Calbindins; Calcimycin; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Hippocampus; Immunohistochemistry; Ionophores; Kainic Acid; Lymphotoxin-alpha; Male; Malonates; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G; Tumor Necrosis Factor-alpha | 1995 |
Differential cellular response after glutamate analog hippocampal damage.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Biomarkers; Brain; Brain Injuries; Cerebral Cortex; Cerebral Ventricles; Corpus Callosum; Glial Fibrillary Acidic Protein; Gliosis; Glutamic Acid; Hippocampus; Immunohistochemistry; Injections, Intraventricular; Kainic Acid; Male; Microglia; Neurons; Rats; Rats, Wistar | 1996 |
Hemoglobin potentiates excitotoxic injury in cortical cell culture.
Topics: Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Antioxidants; Brain Injuries; Cells, Cultured; Cerebral Cortex; Chromans; Deferoxamine; Drug Synergism; Excitatory Amino Acids; Hemoglobin A; Humans; Kainic Acid; Kinetics; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Neuroglia; Neurons | 1996 |
Strong induction of activin expression after hippocampal lesion.
Topics: Activins; Animals; Brain Injuries; Female; Hippocampus; In Situ Hybridization; Inhibins; Kainic Acid; Mice; Mice, Inbred C57BL; RNA, Messenger | 1996 |
A common morphological response of astrocytes to various injuries: "dark" astrocytes. A light and electron microscopic analysis.
Topics: Animals; Astrocytes; Brain; Brain Injuries; Craniocerebral Trauma; Female; Kainic Acid; Male; Microscopy, Electron; Neurons; Pentylenetetrazole; Rats; Rats, Wistar | 1997 |
Upregulation of L-type Ca2+ channels in reactive astrocytes after brain injury, hypomyelination, and ischemia.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Astrocytes; Brain Injuries; Brain Ischemia; Calcium Channels; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Agonists; Gerbillinae; Glial Fibrillary Acidic Protein; Gliosis; Homeostasis; Hot Temperature; Injections, Intraventricular; Kainic Acid; Male; Mice; Mice, Neurologic Mutants; Myelin Sheath; Rats; Up-Regulation; Wounds, Stab | 1998 |
Kainic acid lesions of the superior olivary complex: effects on sound localization by the albino rat.
Topics: Animals; Auditory Pathways; Brain Injuries; Brain Mapping; Brain Stem; Excitatory Amino Acid Agonists; Kainic Acid; Male; Pons; Rats; Rats, Wistar; Sound Localization | 1998 |
Beta-actin immunoreactivity in rat microglial cells: developmental pattern and participation in microglial reaction after kainate injury.
Topics: Actins; Animals; Antibodies, Monoclonal; Brain Injuries; Immunohistochemistry; Kainic Acid; Male; Microglia; Rats; Rats, Wistar | 1998 |
Distinct roles for sodium, chloride, and calcium in excitotoxic dendritic injury and recovery.
Topics: Animals; Brain Injuries; Bridged Bicyclo Compounds; Calcium; Cells, Cultured; Chlorides; Coculture Techniques; Cytosol; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; Microscopy, Fluorescence; N-Methylaspartate; Quinoxalines; Receptors, Glutamate; Sodium; Veratridine | 1998 |
Aromatase expression by astrocytes after brain injury: implications for local estrogen formation in brain repair.
Topics: Animals; Aromatase; Astrocytes; Brain; Brain Diseases; Brain Injuries; Estrogens; Female; Kainic Acid; Male; Mice; Mice, Inbred BALB C; Rats; Rats, Wistar; Wound Healing; Wounds, Penetrating | 1999 |
Injury induces neuropsin mRNA in the central nervous system.
Topics: Animals; Brain Injuries; In Situ Hybridization; Kainic Acid; Kallikreins; Mice; RNA, Messenger; Serine Endopeptidases; Spinal Cord Injuries | 1999 |
Fra-1 immunoreactivity in the rat brain during normal postnatal development and after injury in adulthood.
Topics: Aging; Animals; Animals, Newborn; Blotting, Western; Brain; Brain Injuries; Gene Expression Regulation; Gene Expression Regulation, Developmental; Glial Fibrillary Acidic Protein; Immunohistochemistry; Kainic Acid; Neurons; Organ Specificity; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley | 1999 |
Connective tissue growth factor: a novel player in tissue reorganization after brain injury?
Topics: Animals; Brain Injuries; Connective Tissue Growth Factor; Fibronectins; Functional Laterality; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Growth Substances; Hippocampus; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Time Factors | 2000 |
Evidence disputing the importance of excitotoxicity in hippocampal neuron death after experimental traumatic brain injury.
Topics: Animals; Brain Injuries; Cell Survival; Excitatory Amino Acid Agonists; Exocytosis; Hippocampus; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Neurons | 1999 |
Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury.
Topics: Animals; Biotin; Blood-Brain Barrier; Brain Injuries; Erythropoietin; Female; Kainic Acid; Male; Mice; Mice, Inbred BALB C; Neuroprotective Agents; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Receptors, Erythropoietin; Recombinant Proteins; Seizures | 2000 |
Cloning and expression of MP13 gene from rat hippocampus, a new factor related to guanosine triphosphate regulation.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain Injuries; Cell Survival; Cloning, Molecular; Gene Expression Regulation; Guanosine Triphosphate; Hippocampus; Kainic Acid; Molecular Sequence Data; Neurons; Proto-Oncogene Proteins c-fos; Rats; Transcription Factors | 2000 |
Expression of neuropsin in oligodendrocytes after injury to the CNS.
Topics: Animals; Axons; Brain Injuries; Excitatory Amino Acid Agonists; Eye Enucleation; Hippocampus; Immunohistochemistry; Kainic Acid; Kallikreins; Mice; Myelin Basic Protein; Nerve Degeneration; Oligodendroglia; Optic Nerve; Pyramidal Cells; RNA, Messenger; Serine Endopeptidases | 2001 |
Activated astrocytes in areas of kainate-induced neuronal injury upregulate the expression of the metabotropic glutamate receptors 2/3 and 5.
Topics: Adaptation, Physiological; Animals; Astrocytes; Brain Injuries; COS Cells; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Gliosis; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Mice; Nerve Degeneration; Nerve Regeneration; Neuronal Plasticity; Pyramidal Cells; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Up-Regulation | 2001 |
Gene therapy effectiveness differs for neuronal survival and behavioral performance.
Topics: Animals; Behavior, Animal; Brain Injuries; Calbindins; Cell Survival; Genes, Reporter; Genetic Therapy; Genetic Vectors; Hippocampus; Kainic Acid; Male; Nerve Tissue Proteins; Neurons; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G; Simplexvirus; Time Factors | 2001 |
Lactate dehydrogenase release is facilitated by brief sonication of rat hippocampal slices and isolated retinas following acute neuronal damage.
Topics: Acute Disease; Animals; Brain Injuries; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hippocampus; Iodoacetates; Kainic Acid; L-Lactate Dehydrogenase; Nerve Degeneration; Neurochemistry; Neurons; Neurotoxins; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Retina; Sonication | 2001 |
Sustained, long-lasting inhibition of nitric oxide synthase aggravates the neural damage in some models of excitotoxic brain injury.
Topics: Animals; Basal Nucleus of Meynert; Brain; Brain Injuries; Calcium Channel Blockers; Choline O-Acetyltransferase; Cholinergic Fibers; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamate Decarboxylase; Ibotenic Acid; Immunohistochemistry; Kainic Acid; Male; NADPH Dehydrogenase; Neostriatum; Nerve Degeneration; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Verapamil | 2001 |
Systemic administration of kainic acid in adult rat stimulates expression of the chemokine receptor CCR5 in the forebrain.
Topics: Animals; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Avian Proteins; Basigin; Blood Proteins; Brain Injuries; Chemokines; Excitatory Amino Acid Agonists; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Gliosis; Immunohistochemistry; Kainic Acid; Membrane Glycoproteins; Nerve Degeneration; Neuroglia; Neurons; Neurotoxins; Phosphopyruvate Hydratase; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, CCR5; RNA, Messenger; Up-Regulation | 2002 |
Transient expression of juvenile-type neurocan by reactive astrocytes in adult rat brains injured by kainate-induced seizures as well as surgical incision.
Topics: Animals; Astrocytes; Blotting, Western; Brain Injuries; Chondroitin Sulfate Proteoglycans; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Kainic Acid; Lectins, C-Type; Membrane Glycoproteins; Membrane Proteins; Nerve Tissue Proteins; Neurocan; Proteoglycans; Rats; Rats, Sprague-Dawley; Receptor-Like Protein Tyrosine Phosphatases, Class 5; RNA, Messenger; Seizures; Syndecan-3; Time Factors | 2002 |
Studies of activated microglial cells and macrophages using Alzheimer's disease cerebrospinal fluid in adult rats with experimentally induced lesions.
Topics: Alzheimer Disease; Animals; Antibodies, Monoclonal; Brain Injuries; Freezing; Immunohistochemistry; Kainic Acid; Macrophages; Male; Microscopy, Immunoelectron; Neuroglia; Rats; Rats, Wistar | 1992 |
Excitatory amino acid receptor subtype binding following traumatic brain injury.
Topics: Animals; Brain Injuries; Kainic Acid; Oxadiazoles; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Intracortical grafts of embryonic basal forebrain tissue restore low voltage fast activity in rats with basal forebrain lesions.
Topics: Acetylcholinesterase; Animals; Brain; Brain Injuries; Cerebral Cortex; Electrophysiology; Embryo, Mammalian; Functional Laterality; Kainic Acid; Male; Nerve Tissue; Rats; Transplantation, Heterotopic | 1990 |