kainic acid has been researched along with Brain Disorders in 78 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (30.77) | 18.7374 |
| 1990's | 27 (34.62) | 18.2507 |
| 2000's | 21 (26.92) | 29.6817 |
| 2010's | 5 (6.41) | 24.3611 |
| 2020's | 1 (1.28) | 2.80 |
| Authors | Studies |
|---|---|
| Bunney, W; Limon, A; Scaduto, P; Sequeira, A; Vawter, MP | 1 |
| Borkowska, S; Fiedorowicz, K; Grymula, K; Kucia, M; Mierzejewska, K; Piotrowska, K; Ratajczak, MZ; Suszynska, M; Tarnowski, M | 1 |
| Ahn, SY; Han, JY; Hong, JT; Nam, SY; Oh, KW; Yoo, JH | 1 |
| Chara, JC; Cipriani, R; Matute, C; Rodríguez-Antigüedad, A | 1 |
| Chang, Y; Huang, SK; Lin, TY; Lu, CW; Wang, SJ | 1 |
| Pulido, OM | 1 |
| Gao, S; Ho, G; Kng, YL; Kumar, S; Loh, MY; Min, XS; Zhuo, L | 1 |
| de la Riva, GT; Gulland, FM; Heyning, JE; Johnson, CK; Langlois, GW; Mazet, JA; Rowles, TK | 1 |
| Barakos, J; Battey, TW; Colegrove, K; Dennison, S; Gulland, F; Montie, EW; Pussini, N; Wheeler, E | 1 |
| Lu, A; Nee, AC; Ran, R; Sharp, FR; Tang, Y | 1 |
| Lichtman, AH; Mechoulam, R | 1 |
| Chao, BB; Peng, YP; Qiu, YH; Wang, JJ | 1 |
| Galea, I; Newman, TA; Perry, VH; van Rooijen, N | 1 |
| Akcay, YD; Sozmen, EY; Yalcin, A | 1 |
| Chen, CL; Chiang, SY; Chuang, CM; Hsieh, CL; Hsieh, CT; Hsu, SF; Lin, JG; Tang, NY | 1 |
| Janeczko, K; Janicka, D; Kowalczyk, A; Setkowicz, Z; Turlej, A | 1 |
| Drago, F; Ignoto, A; Incognito, T; Micale, V; Rampello, L; Spartà, M | 1 |
| Cui, HS; Kim, MR; Sok, DE | 1 |
| Hashizume, K; Hodozuka, A; Tanaka, T; Tsuda, H | 1 |
| Fowler, KR; Olton, DS | 1 |
| Collins, JF; Parks, DA; Schwarcz, R | 1 |
| Bird, ED; Hefti, F; Melamed, E | 1 |
| Huston, JP; Pritzel, M; Sarter, M | 1 |
| Henn, V; Hepp, K; Lang, W; Reisine, H | 1 |
| Chan, SH; Lai, YY | 1 |
| Aldinio, C; French, ED; Schwarcz, R | 1 |
| Hefti, F; Liebman, J; Melamed, E; Pettibone, DJ; Wurtman, RJ | 1 |
| Berg, M; Bruhn, T; Diemer, NH; Frandsen, A; Schousboe, A | 1 |
| Castellano, B; Diemer, NH; Finsen, BR; Jensen, MB; Jørgensen, MB; Zimmer, J | 1 |
| Lehmann, JC; Procureur, D; Wood, PL | 1 |
| Cutler, RC; Joseph, JA | 1 |
| Kondoh, T; Low, WC | 1 |
| Aramnejad, E; Ceserani, R; Costa, G; Lanza, M; Pisani, A; Princi, P; Saija, A; Scalese, M | 1 |
| Chronopoulos, A; Gatt, A; Holmes, GL; Hyde, P; Liu, Z; Mikati, MA; Stafstrom, CE; Thurber, S; Werner, S | 1 |
| Ben Ari, Y; Cantagrel, S; Charriaut-Marlangue, C; Moreau, J; Pollard, H | 1 |
| Diemer, NH; Finsen, BR; Jørgensen, MB; Zimmer, J | 1 |
| Carmant, L; Holmes, GL; Liu, Z; Mikati, MA; Werner, SJ | 1 |
| Suzuki, Y | 1 |
| Floreani, M; Franceschini, D; Giusti, P; Manev, H; Petrone, M | 1 |
| Lei, DL; Liu, HM; Yang, DL | 1 |
| Bardgett, ME; Csernansky, CA; Csernansky, JG; Roe, DL | 1 |
| Bruce-Keller, AJ; Mattson, MP; McFall, R; Umberger, G | 1 |
| Azcoitia, I; Garcia-Segura, LM; Hutchison, JB; Hutchison, RE; Rodriguez, JR; Wozniak, A | 1 |
| Engelhardt, RT; Johannessen, JN; Johnson, GA; Lester, DS; Lyon, RC; McGregor, GN; Schmued, LC | 1 |
| Clarke, EE; Gervais, FG; Huang, J; LeBlanc, A; Nicholson, DW; Rigby, M; Robertson, GS; Roy, S; Ruffolo, SC; Shearman, MS; Smith, D; Thornberry, NA; Vaillancourt, JP; Van Der Ploeg, LH; Xanthoudakis, S; Xu, D; Zamboni, RJ; Zheng, H; Zhu, Y | 1 |
| Aisen, PS; Mukherjee, P; Osaka, H; Pasinetti, GM | 1 |
| Gerard, C; Höepken, UE; Lu, B; McGinty, A; Osaka, H; Pasinetti, GM | 1 |
| Qiao, M; Zhang, S | 1 |
| Benson, S; Busman, M; Chavez, FP; Cordaro, J; De Vogelaere, A; DeLong, R; Doucette, GJ; Gulland, F; Harvey, J; Haulena, M; Lefebvre, K; Lipscomb, T; Loscutoff, S; Lowenstine, LJ; Marin, R; McLellan, WA; Miller, PE; Moeller, PD; Powell, CL; Rowles, T; Scholin, CA; Silvagni, P; Silver, M; Spraker, T; Trainer, V; Van Dolah, FM | 1 |
| Bouilleret, V; Marescaux, C; Namer, IJ; Nehlig, A | 1 |
| Beravs, K; Demsar, F; Frangez, R | 1 |
| Katzir, H; Mathern, GW; Mendoza, D | 1 |
| Akhtar, N; Bu, J; Nishiyama, A | 1 |
| Baudry, M; Bi, R; Chun, JT; Hoe, W; Liu, R; Liu, W; Schreiber, SS | 1 |
| Ayala-Guerrero, F; Gonzalez-Maciel, A; Reynoso-Robles, R; Romero-Velazquez, RM; Vargas, L | 1 |
| Alzheimer, C; Braun, S; Durka, S; Hertel, M; Werner, S | 1 |
| Ben-Ari, Y; Ottersen, OP; Tremblay, E | 1 |
| Fibiger, HC; Sanberg, PR | 1 |
| Hertzberg, EL; Nagy, JI; Vukelic, JI; Yamamoto, T | 1 |
| Clark, AJ; Hastings, MH; Latimer, M; Stone, TW; Winn, P | 1 |
| Matthews, JC; Scallet, AC | 1 |
| Kaplan, SM; Nash, DR; Norman, AB; Sanberg, PR | 1 |
| Bédard, L; Hockin, JC; Kosatsky, T; Perl, TM; Remis, RS; Todd, EC | 1 |
| Attwell, D; Barbour, B; Szatkowski, M | 1 |
| Hunt, SP; Mantyh, PW | 1 |
| Kaijima, M; Tanaka, S; Tanaka, T; Yonemasu, Y | 1 |
| Go, KG; Gramsbergen, JB; Korf, J; Prenen, GH | 1 |
| Allen, GS; Luo, SQ; Tulipan, N; Whetsell, WO | 1 |
| Asanuma, H; Kosar, E; Robinson, H; Tsukahara, N | 1 |
| Deckel, AW; Moran, TH; Robinson, RG | 1 |
| Gramsbergen, JB; Korf, J; Loopuijt, L; Paans, AM; Vaalburg, W; Veenma-van der Duin, L | 1 |
| Delepierre, M; Isacson, O; Peschanski, M; Roques, BP; Rudin, M | 1 |
| Armstrong, DR; Ault, B; Gruenthal, M; Nadler, JV | 1 |
| Diemer, NH; Johansen, FF | 1 |
| Anderson, KJ; DeKosky, ST; Scheff, SW | 1 |
| Choi, DW; Koh, JY | 1 |
| Coyle, JT; Deckel, AW; Moran, TH; Robinson, RG; Sanberg, PR | 1 |
| Gage, FH; Kesslak, JP | 1 |
3 review(s) available for kainic acid and Brain Disorders
| Article | Year |
|---|---|
Domoic acid toxicologic pathology: a review.
Topics: Age Factors; Animals; Brain Diseases; Canada; Humans; Kainic Acid; Mollusca; Sex Factors; Shellfish Poisoning | 2008 |
The role of oxidative stress in signal transduction changes and cell loss in senescence.
Topics: Aging; Animals; Antioxidants; Brain; Brain Diseases; Cyclic N-Oxides; Free Radicals; Humans; Hydroxyl Radical; Kainic Acid; Neurons; Nitrogen Oxides; Oxidative Stress; Signal Transduction; Spin Labels | 1994 |
Cation shifts and excitotoxins in Alzheimer and Huntington disease and experimental brain damage.
Topics: Aged; Alzheimer Disease; Amino Acids; Animals; Brain; Brain Diseases; Calcium; Cations; gamma-Aminobutyric Acid; Humans; Huntington Disease; Kainic Acid; Middle Aged; Neurotoxins; Tetrodotoxin | 1986 |
75 other study(ies) available for kainic acid and Brain Disorders
| Article | Year |
|---|---|
Preservation of global synaptic excitatory to inhibitory ratio during long postmortem intervals.
Topics: Adult; Animals; Brain; Brain Diseases; Excitatory Postsynaptic Potentials; Female; gamma-Aminobutyric Acid; Humans; Inhibitory Postsynaptic Potentials; Kainic Acid; Male; Oocytes; Rats; Rats, Wistar; Receptors, Neurotransmitter; Synaptosomes; Temperature; Time Factors | 2020 |
Evidence that the population of quiescent bone marrow-residing very small embryonic/epiblast-like stem cells (VSELs) expands in response to neurotoxic treatment.
Topics: Animals; Bone Marrow Cells; Brain Diseases; Cell Movement; Cell Proliferation; Cells, Cultured; Dentate Gyrus; Embryonic Stem Cells; Flow Cytometry; Kainic Acid; Male; Mice, Inbred C57BL | 2014 |
Alleviation of kainic acid-induced brain barrier dysfunction by 4-o-methylhonokiol in in vitro and in vivo models.
Topics: Animals; Antioxidants; Biphenyl Compounds; Blood-Brain Barrier; Brain Diseases; Capillary Permeability; Kainic Acid; Lignans; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2015 |
FTY720 attenuates excitotoxicity and neuroinflammation.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Brain Diseases; Cell Death; Cells, Cultured; Cerebellum; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Fingolimod Hydrochloride; In Vitro Techniques; Kainic Acid; L-Lactate Dehydrogenase (Cytochrome); Male; N-Methylaspartate; Neurons; Organ Culture Techniques; Phosphorylation; Rats; Rats, Sprague-Dawley; Time Factors | 2015 |
Baicalein, a Constituent of Scutellaria baicalensis, Reduces Glutamate Release and Protects Neuronal Cell Against Kainic Acid-Induced Excitotoxicity in Rats.
Topics: Animals; Brain; Brain Diseases; Calcium; Calcium Channels, N-Type; Excitatory Postsynaptic Potentials; Flavanones; Glutamic Acid; Humans; Kainic Acid; Male; Neurons; Plant Extracts; Protective Agents; Rats; Rats, Sprague-Dawley; Scutellaria baicalensis | 2016 |
Molecular imaging of retinal gliosis in transgenic mice induced by kainic acid neurotoxicity.
Topics: Animals; Brain Diseases; Diagnostic Imaging; Disease Models, Animal; Excitatory Amino Acid Agonists; Fluorescence; Glial Fibrillary Acidic Protein; Gliosis; Green Fluorescent Proteins; Immunohistochemistry; Injections, Intraperitoneal; Kainic Acid; Mice; Mice, Transgenic; Neurotoxicity Syndromes; Ophthalmoscopes; Optic Nerve; Retinal Diseases | 2009 |
Association of an unusual marine mammal mortality event with Pseudo-nitzschia spp. Blooms along the southern California coastline.
Topics: Animals; Brain Diseases; California; Environmental Monitoring; Epidemiological Monitoring; Eutrophication; Female; Food Chain; Kainic Acid; Male; Marine Toxins; Mortality; Neurotoxins; Poisoning; Sea Lions; Seasons | 2009 |
Magnetic resonance imaging quality and volumes of brain structures from live and postmortem imaging of California sea lions with clinical signs of domoic acid toxicosis.
Topics: Animals; Brain; Brain Diseases; Kainic Acid; Magnetic Resonance Imaging; Marine Toxins; Sea Lions | 2010 |
Blood genomic expression profile for neuronal injury.
Topics: Animals; Blood Physiological Phenomena; Brain Diseases; Down-Regulation; Gene Expression Profiling; Genome; Ischemic Attack, Transient; Kainic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Monocytes; Neuropeptides; Oligonucleotide Array Sequence Analysis; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seizures; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2003 |
Neuroscience. Stout guards of the central nervous system.
Topics: Animals; Anticonvulsants; Arachidonic Acids; Brain; Brain Diseases; Cannabidiol; Cannabinoid Receptor Modulators; Cannabinoids; Convulsants; Dronabinol; Endocannabinoids; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycerides; Humans; Kainic Acid; Mice; Neurons; Neuroprotective Agents; Polyunsaturated Alkamides; Rats; Receptors, Cannabinoid; Receptors, Drug; Signal Transduction | 2003 |
Effect of lesions of cerebellar fastigial nuclei on lymphocyte functions of rats.
Topics: Animals; Biogenic Monoamines; Brain Chemistry; Brain Diseases; Cell Death; Cell Proliferation; Cerebellar Nuclei; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Flow Cytometry; Glutamic Acid; Hypothalamus; Kainic Acid; Killer Cells, Natural; Lymphocyte Activation; Lymphocytes; Macrolides; Quinolines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Staining and Labeling; Tetrazolium Salts; Thiazoles; Time Factors; Urea | 2005 |
Blood-derived dendritic cells in an acute brain injury.
Topics: Acute Disease; Animals; Antigens, Differentiation; Biomarkers; Bone Marrow; Brain Diseases; Cell Line; Dendritic Cells; Excitatory Amino Acid Agonists; Kainic Acid; Male; Rats; Rats, Inbred Lew; T-Lymphocytes; Time Factors; Whole-Body Irradiation | 2005 |
The effect of melatonin on lipid peroxidation and nitrite/nitrate levels, and on superoxide dismutase and catalase activities in kainic acid-induced injury.
Topics: Animals; Brain Diseases; Catalase; Kainic Acid; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Nitrates; Nitrites; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2005 |
Gastrodia elata BL mediates the suppression of nNOS and microglia activation to protect against neuronal damage in kainic acid-treated rats.
Topics: Animals; Apoptosis; Brain Diseases; Drugs, Chinese Herbal; Excitatory Amino Acid Agonists; Gastrodia; Hippocampus; Kainic Acid; Male; Microglia; Nerve Tissue Proteins; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley | 2005 |
Congenital brain dysplasias of different genesis can differently affect susceptibility to pilocarpine- or kainic acid-induced seizures in the rat.
Topics: Animals; Behavior, Animal; Brain Diseases; Convulsants; Dose-Response Relationship, Drug; Electroencephalography; Female; Gamma Rays; Kainic Acid; Pilocarpine; Pregnancy; Radiation Injuries, Experimental; Rats; Rats, Wistar; Seizures; Status Epilepticus | 2005 |
Dopaminergic drugs may counteract behavioral and biochemical changes induced by models of brain injury.
Topics: Amnesia; Animals; Antioxidants; Behavior, Animal; Brain Diseases; Brain Ischemia; Dopamine Agents; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Agonists; Glutathione; Hypoxia, Brain; Injections, Intraventricular; Injections, Subcutaneous; Kainic Acid; Male; Motor Activity; Oxidation-Reduction; Rats; Rats, Sprague-Dawley | 2006 |
Protection by petaslignolide A, a major neuroprotective compound in the butanol extract of Petasites japonicus leaves, against oxidative damage in the brains of mice challenged with kainic acid.
Topics: Animals; Blood-Brain Barrier; Brain Diseases; Butanols; Enzyme Induction; Furans; Glutathione; Kainic Acid; Lignans; Male; Mice; Mice, Inbred ICR; Neuroprotective Agents; Oxidative Stress; Petasites; Plant Extracts; Plant Leaves | 2005 |
Focal cortical dysplasia: pathophysiological approach.
Topics: Adolescent; Animals; Animals, Newborn; Autoradiography; Behavior, Animal; Brain Diseases; Brain Mapping; Cerebral Cortex; Child; Electroencephalography; Epilepsy; Female; Flumazenil; gamma-Aminobutyric Acid; Humans; Immunohistochemistry; Iodine Radioisotopes; Kainic Acid; Male; Nervous System Malformations; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2006 |
Recovery of function following injections of kainic acid: behavioral, electrophysiological and neuroanatomical correlates.
Topics: Animals; Brain Diseases; Conditioning, Classical; Discrimination Learning; Evoked Potentials; Hippocampus; Kainic Acid; Male; Memory; Pyrrolidines; Rats; Rats, Inbred Strains; Synaptic Transmission | 1984 |
alpha-Amino-omega-phosphono carboxylates block ibotenate but not kainate neurotoxicity in rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain Diseases; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Neurotoxins; Oxazoles; Pyrrolidines; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Valine | 1982 |
Huntington chorea is not associated with hyperactivity of nigrostriatal dopaminergic neurons: studies in postmortem tissues and in rats with kainic acid lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Diseases; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Humans; Huntington Disease; Kainic Acid; Male; Middle Aged; Neurons; Rats; Rats, Inbred Strains | 1982 |
Behavioral and neuronal reorganization after unilateral substantia nigra lesions: evidence for increased interhemispheric nigrostriatal projections.
Topics: Animals; Behavior, Animal; Brain Diseases; Brain Mapping; Catecholamines; Corpus Striatum; Hydroxydopamines; Kainic Acid; Male; Neural Pathways; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1983 |
Experimental gaze palsies in monkeys and their relation to human pathology.
Topics: Animals; Brain Diseases; Chlorocebus aethiops; Eye Movements; Kainic Acid; Macaca mulatta; Ophthalmoplegia; Pons; Reticular Formation | 1984 |
Antagonization of clonidine- and morphine-promoted antinociception by kainic acid lesion of nucleus reticularis gigantocellularis in the rat.
Topics: Animals; Brain Diseases; Clonidine; Kainic Acid; Male; Morphine; Nociceptors; Pain; Rats; Rats, Inbred Strains; Reticular Formation | 1982 |
Intrahippocampal kainic acid, seizures and local neuronal degeneration: relationships assessed in unanesthetized rats.
Topics: Animals; Brain Diseases; Convulsants; Dose-Response Relationship, Drug; Electroencephalography; Hippocampus; Kainic Acid; Male; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures | 1982 |
Aromatic L-amino acid decarboxylase in rat corpus striatum: implications for action of L-dopa in parkinsonism.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Brain Diseases; Corpus Striatum; Dopamine; Glutamate Decarboxylase; Kainic Acid; Levodopa; Male; Neurons; Parkinson Disease; Rats; Serotonin | 1981 |
Kainic acid-induced seizures and brain damage in the rat: role of calcium homeostasis.
Topics: Animals; Behavior, Animal; Body Temperature; Brain Diseases; Calcium; Calcium Channels; Dantrolene; Homeostasis; Ion Channel Gating; Kainic Acid; Male; Nimodipine; Pyramidal Cells; Rats; Rats, Wistar; Seizures | 1995 |
Microglial and astroglial reactions to ischemic and kainic acid-induced lesions of the adult rat hippocampus.
Topics: Acid Anhydride Hydrolases; Animals; Astrocytes; Brain Diseases; Brain Ischemia; Hippocampus; Immunoglobulin G; Immunohistochemistry; Intermediate Filament Proteins; Kainic Acid; Macrophage-1 Antigen; Male; Neuroglia; Phosphoric Monoester Hydrolases; Rats; Rats, Wistar; Staining and Labeling | 1993 |
7-Chlorokynurenate prevents NMDA-induced and kainate-induced striatal lesions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Diseases; Choline O-Acetyltransferase; Corpus Striatum; Dose-Response Relationship, Drug; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine | 1993 |
Glutamate uptake blockade induces striatal dopamine release in 6-hydroxydopamine rats with intrastriatal grafts: evidence for host modulation of transplanted dopamine neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Diseases; Brain Tissue Transplantation; Corpus Striatum; Dopamine; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Kainic Acid; Male; Mesencephalon; N-Methylaspartate; Neurons; Oxidopamine; Rats; Tyrosine 3-Monooxygenase | 1994 |
Protective effect of glutathione on kainic acid-induced neuropathological changes in the rat brain.
Topics: Animals; Behavior, Animal; Brain; Brain Diseases; Glucose; Glutathione; Hippocampus; Kainic Acid; Male; Rats; Rats, Wistar; Seizures; Water | 1994 |
Phenobarbital modifies seizure-related brain injury in the developing brain.
Topics: Aging; Analysis of Variance; Animals; Brain Diseases; Kainic Acid; Male; Phenobarbital; Rats; Rats, Sprague-Dawley; Recurrence; Seizures; Status Epilepticus | 1994 |
Apoptosis associated DNA fragmentation in epileptic brain damage.
Topics: Amygdala; Animals; Apoptosis; Brain Diseases; DNA; Epilepsy; Hippocampus; Injections; Kainic Acid; Male; Rats; Rats, Wistar | 1994 |
Microglial MHC antigen expression after ischemic and kainic acid lesions of the adult rat hippocampus.
Topics: Animals; Brain Diseases; Brain Ischemia; Hippocampus; Histocompatibility Antigens; Kainic Acid; Leukocyte Common Antigens; Male; Nerve Degeneration; Neuroglia; Rats; Rats, Wistar | 1993 |
Effect of kainic acid-induced status epilepticus on inositol-trisphosphate and seizure-induced brain damage in mature and immature animals.
Topics: Aging; Animals; Brain Diseases; Excitatory Amino Acids; Inositol Phosphates; Kainic Acid; Male; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus | 1995 |
[Changes of torsional eye movements after lesion of the rostral interstitial nucleus of the MLF (riMLF)--analysis on listing's plane].
Topics: Animals; Brain Diseases; Eye Movements; Kainic Acid; Macaca mulatta; Tegmentum Mesencephali | 1995 |
In vitro and in vivo protection against kainate-induced excitotoxicity by melatonin.
Topics: Animals; Ascorbic Acid; Brain; Brain Diseases; Dose-Response Relationship, Drug; Ferric Compounds; Kainic Acid; Lipid Peroxidation; Male; Melatonin; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Synaptosomes | 1996 |
Kainate-induced brain lesion: similar local and remote histopathological and molecular changes as in ischemic brain infarct.
Topics: Animals; Brain; Brain Diseases; Brain Ischemia; Cerebral Infarction; Kainic Acid; Male; Microinjections; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Staining and Labeling; Time Factors | 1996 |
Induction of Fos protein by antipsychotic drugs in rat brain following kainic acid-induced limbic-cortical neuronal loss.
Topics: Animals; Antipsychotic Agents; Brain; Brain Diseases; Cell Count; Clozapine; Dose-Response Relationship, Drug; Gene Expression; Genes, fos; Haloperidol; Kainic Acid; Limbic System; Male; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley | 1998 |
Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults.
Topics: Animals; Antihypertensive Agents; Behavior, Animal; Brain Diseases; Corpus Striatum; Diet; Energy Intake; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Malonates; Maze Learning; Memory; Mitochondria; Neurotoxins; Nitro Compounds; Oxidative Stress; Propionates; Rats; Rats, Sprague-Dawley; Visual Cortex | 1999 |
Aromatase expression by astrocytes after brain injury: implications for local estrogen formation in brain repair.
Topics: Animals; Aromatase; Astrocytes; Brain; Brain Diseases; Brain Injuries; Estrogens; Female; Kainic Acid; Male; Mice; Mice, Inbred BALB C; Rats; Rats, Wistar; Wound Healing; Wounds, Penetrating | 1999 |
3-Dimensional visualization of lesions in rat brain using magnetic resonance imaging microscopy.
Topics: Animals; Brain; Brain Diseases; Histocytochemistry; Image Processing, Computer-Assisted; Kainic Acid; Magnetic Resonance Imaging; Microscopy; Neurotoxins; Rats | 1999 |
Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation.
Topics: Acute Disease; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Amyloidosis; Animals; Apoptosis; Aspartic Acid; Aspartic Acid Endopeptidases; Brain Diseases; Camptothecin; Caspase 3; Caspases; Cysteine Proteinase Inhibitors; Endopeptidases; Enzyme Inhibitors; Enzyme Precursors; Excitatory Amino Acid Agonists; Hippocampus; Humans; In Situ Nick-End Labeling; Kainic Acid; Leukemia, Erythroblastic, Acute; Male; Mice; Mice, Inbred C57BL; Mutation; Neurons; Oligopeptides; Rabbits; Rats; Rats, Wistar; Sweden; Tumor Cells, Cultured | 1999 |
Complement-derived anaphylatoxin C5a protects against glutamate-mediated neurotoxicity.
Topics: Alzheimer Disease; Animals; Blotting, Northern; Brain; Brain Diseases; Caspase 3; Caspases; Cells, Cultured; Complement C5a; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Humans; Kainic Acid; Mice; Neurotoxins; Recombinant Proteins; Time Factors | 1999 |
Expression of C5a receptor in mouse brain: role in signal transduction and neurodegeneration.
Topics: Animals; Brain; Brain Diseases; Cells, Cultured; Complement C5a; Humans; Kainic Acid; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Nerve Degeneration; Neuroglia; Neurons; Receptors, Complement; Recombinant Proteins; RNA, Messenger; Signal Transduction | 1999 |
[Beneficial effect and mechanism of 764-3 on cognitive deficit induced by brain damage in rats].
Topics: Animals; Brain Diseases; Ca(2+) Mg(2+)-ATPase; Cognition Disorders; Drugs, Chinese Herbal; Kainic Acid; Male; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase | 1997 |
Mortality of sea lions along the central California coast linked to a toxic diatom bloom.
Topics: Animals; Bivalvia; Brain Diseases; California; Chromatography, Liquid; Diatoms; Eutrophication; Fishes; Food Chain; Humans; Kainic Acid; Marine Toxins; Mass Spectrometry; Mortality; Neurotoxins; Poisoning; Sea Lions | 2000 |
Magnetic resonance imaging follow-up of progressive hippocampal changes in a mouse model of mesial temporal lobe epilepsy.
Topics: Animals; Brain Diseases; Disease Models, Animal; Epilepsy, Temporal Lobe; Follow-Up Studies; Functional Laterality; Gadolinium; Hippocampus; Image Enhancement; Kainic Acid; Magnetic Resonance Imaging; Mice; Microinjections; Nerve Degeneration; Sclerosis; Seizures; Status Epilepticus | 2000 |
Assessment of kainate toxicity using contrast enhanced magnetic resonance imaging.
Topics: Animals; Brain; Brain Diseases; Contrast Media; Gadolinium; Gadolinium DTPA; Image Enhancement; Kainic Acid; Magnetic Resonance Imaging; Polylysine; Rats; Rats, Wistar | 2000 |
Effect of theophylline and trimethobenzamide when given during kainate-induced status epilepticus: an improved histopathologic rat model of human hippocampal sclerosis.
Topics: Animals; Benzamides; Brain Diseases; Cell Count; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Humans; Hypertension; Kainic Acid; Mossy Fibers, Hippocampal; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Sclerosis; Status Epilepticus; Theophylline | 2000 |
Transient expression of the NG2 proteoglycan by a subpopulation of activated macrophages in an excitotoxic hippocampal lesion.
Topics: Animals; Antigens; Astrocytes; Brain Diseases; Female; Glial Fibrillary Acidic Protein; Hippocampus; Humans; Kainic Acid; Macrophage-1 Antigen; Macrophages; Membrane Proteins; Microglia; Neurotoxins; Proteoglycans; Rats; Rats, Sprague-Dawley; Receptor, Platelet-Derived Growth Factor alpha; Time Factors; Tumor Cells, Cultured | 2001 |
Kainate excitotoxicity in organotypic hippocampal slice cultures: evidence for multiple apoptotic pathways.
Topics: Amino Acid Chloromethyl Ketones; Animals; Animals, Newborn; Apoptosis; bcl-2-Associated X Protein; Brain Diseases; Caspase Inhibitors; Caspases; Cells, Cultured; Cyclosporine; Cytochrome c Group; Cytosol; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hippocampus; Immunohistochemistry; Kainic Acid; Membrane Potentials; Mitochondria; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyramidal Cells; Rats; RNA, Messenger | 2001 |
Effect of an anticonvulsant drug on kainic acid-induced brain damage.
Topics: Animals; Anticonvulsants; Behavior, Animal; Brain Diseases; Cerebellar Cortex; Cerebellum; Dentate Gyrus; Excitatory Amino Acid Agonists; Kainic Acid; Male; Nerve Degeneration; Purkinje Cells; Rats; Rats, Wistar | 2001 |
Upregulation and activation of the Nrf-1 transcription factor in the lesioned hippocampus.
Topics: Animals; Brain Diseases; Cell Nucleus; DNA-Binding Proteins; Excitatory Amino Acid Agonists; GA-Binding Protein Transcription Factor; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hippocampus; Kainic Acid; Male; Membrane Proteins; Mice; Neurons; NF-E2-Related Factor 1; Nuclear Respiratory Factor 1; Nuclear Respiratory Factors; RNA, Messenger; Time Factors; Tissue Distribution; Trans-Activators; Transcription Factors; Up-Regulation | 2002 |
[Primary and secondary cerebral lesions produced by kainic acid injections in the rat].
Topics: Amygdala; Animals; Brain Diseases; Hippocampus; Injections; Kainic Acid; Pyrrolidines; Rats; Seizures; Thalamic Nuclei | 1979 |
Body weight, feeding, and drinking behaviors in rats with kainic acid-induced lesions of striatal neurons--with a note on body weight symptomatology in Huntington's disease.
Topics: Animals; Body Weight; Brain Diseases; Corpus Striatum; Disease Models, Animal; Drinking Behavior; Feeding Behavior; Huntington Disease; Kainic Acid; Male; Pyrrolidines; Rats | 1979 |
Depletion of connexin43-immunoreactivity in astrocytes after kainic acid-induced lesions in rat brain.
Topics: Animals; Astrocytes; Brain Diseases; Connexins; Immunohistochemistry; Kainic Acid; Male; Membrane Proteins; Nerve Degeneration; Rats; Rats, Inbred Strains; Thalamus | 1991 |
A comparison of excitotoxic lesions of the basal forebrain by kainate, quinolinate, ibotenate, N-methyl-D-aspartate or quisqualate, and the effects on toxicity of 2-amino-5-phosphonovaleric acid and kynurenic acid in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Brain Diseases; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats | 1991 |
Nutrition, neurotoxicants and age-related neurodegeneration.
Topics: Aging; Amino Acids; Animals; Avoidance Learning; Brain Diseases; Diet; Dietary Proteins; Energy Intake; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Rats; Rats, Inbred F344; Risk Factors; Trimethyltin Compounds | 1991 |
An evaluation of the possible protective effects of neonatal striatal transplants against kainic acid-induced lesions.
Topics: Animals; Animals, Newborn; Body Weight; Brain Diseases; Brain Tissue Transplantation; Corpus Striatum; Kainic Acid; Male; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Seizures; Transplantation, Homologous | 1991 |
An outbreak of toxic encephalopathy caused by eating mussels contaminated with domoic acid.
Topics: Adult; Age Factors; Aged; Animals; Bivalvia; Brain Diseases; Canada; Disease Outbreaks; Female; Follow-Up Studies; Food Contamination; Foodborne Diseases; Gastrointestinal Diseases; Humans; Kainic Acid; Male; Marine Toxins; Memory Disorders; Middle Aged; Neurotransmitter Agents; Prince Edward Island; Sex Factors | 1990 |
Non-vesicular release of glutamate from glial cells by reversed electrogenic glutamate uptake.
Topics: Animals; Biological Transport, Active; Brain Diseases; Extracellular Space; Glutamates; Hypoxia; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neuroglia; Neurons; Potassium; Urodela | 1990 |
Changes in 3H-substance P receptor binding in the rat brain after kainic acid lesion of the corpus striatum.
Topics: Animals; Autoradiography; Binding Sites; Brain Diseases; Corpus Striatum; Kainic Acid; Male; Rats; Rats, Inbred Strains; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Tritium | 1986 |
Ibotenic acid-induced nigral lesion and limbic seizure in cats.
Topics: Animals; Brain Diseases; Cats; Electroencephalography; Female; Ibotenic Acid; Kainic Acid; Limbic System; Male; Oxazoles; Seizures; Substantia Nigra | 1989 |
Striatal grafts provide sustained protection from kainic and quinolinic acid-induced damage.
Topics: Animals; Animals, Newborn; Brain Diseases; Cell Count; Corpus Striatum; Kainic Acid; Neurons; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Lew; Time Factors | 1988 |
Modification of the projection from the sensory cortex to the motor cortex following the elimination of thalamic projections to the motor cortex in cats.
Topics: Animals; Brain Diseases; Cats; Evoked Potentials; Female; Kainic Acid; Male; Motor Cortex; Neuronal Plasticity; Reaction Time; Sensory Deprivation; Somatosensory Cortex; Synaptic Transmission; Thalamic Nuclei | 1985 |
Behavioral recovery following kainic acid lesions and fetal implants of the striatum occurs independent of dopaminergic mechanisms.
Topics: Animals; Brain Diseases; Corpus Striatum; Dopamine; Female; Fetus; Kainic Acid; Movement Disorders; Rats; Rats, Inbred Strains; Receptors, Dopamine; Synaptic Transmission | 1986 |
Imaging of the degeneration of neurons and their processes in rat or cat brain by 45CaCl2 autoradiography or 55CoCl2 positron emission tomography.
Topics: Animals; Autoradiography; Brain; Brain Diseases; Calcium; Calcium Chloride; Calcium Radioisotopes; Cats; Cobalt; Cobalt Radioisotopes; Corpus Striatum; Frontal Lobe; Hippocampus; Hydroxydopamines; Kainic Acid; Male; Nerve Degeneration; Neurons; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra; Tomography, Emission-Computed | 1988 |
Magnetic resonance imaging of intracerebral neural grafts.
Topics: Animals; Brain; Brain Diseases; Kainic Acid; Magnetic Resonance Imaging; Rats; Thalamus | 1988 |
Comparison of seizures and brain lesions produced by intracerebroventricular kainic acid and bicuculline methiodide.
Topics: Animals; Bicuculline; Brain Diseases; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Rats; Rats, Inbred Strains; Seizures | 1986 |
Influence of the plasma glucose level on brain damage after systemic kainic acid injection in the rat.
Topics: Animals; Blood Glucose; Brain Diseases; Hippocampus; Interneurons; Kainic Acid; Male; Rats; Rats, Inbred Strains | 1986 |
Reactive synaptogenesis in hippocampal area CA1 of aged and young adult rats.
Topics: Aging; Animals; Brain Diseases; Hippocampus; Kainic Acid; Male; Microscopy, Electron; Neuronal Plasticity; Rats; Rats, Inbred F344; Synapses | 1986 |
Effect of anticonvulsant drugs on glutamate neurotoxicity in cortical cell culture.
Topics: Animals; Anticonvulsants; Brain Diseases; Cells, Cultured; Cerebral Cortex; Diazepam; Excitatory Amino Acid Antagonists; Glutamates; Kainic Acid; Mice; Phenobarbital; Phenytoin | 1987 |
Anatomical predictors of behavioral recovery following fetal striatal transplants.
Topics: Animals; Behavior, Animal; Brain Diseases; Corpus Striatum; Female; Fetus; Kainic Acid; Memory; Motor Activity; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1986 |
Recovery of spatial alternation deficits following selective hippocampal destruction with kainic acid.
Topics: Animals; Brain Diseases; Ganglia, Sympathetic; Hippocampus; Kainic Acid; Learning Disabilities; Male; Neuronal Plasticity; Rats; Rats, Inbred Strains | 1986 |