Page last updated: 2024-08-21

kainic acid and Amyotrophic Lateral Sclerosis

kainic acid has been researched along with Amyotrophic Lateral Sclerosis in 22 studies

Research

Studies (22)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (9.09)	18.2507
2000's	15 (68.18)	29.6817
2010's	4 (18.18)	24.3611
2020's	1 (4.55)	2.80

Authors

Authors	Studies
Chen, W; Dong, W; Guan, F; Ma, Y; Zhang, L; Zhang, X	1
Bala Krishnan, T; Goh, TE; Mitra, NK; Nadarajah, VD; Soga, T; Vasavaraj, AK	1
Blizzard, CA; Clark, JA; Dawkins, E; Dickson, TC; King, AE; Lewis, KE; Southam, KA	1
Gohar, M; Humayun, S; Leystra-Lantz, C; McLean, J; Mepham, J; Moisse, K; Strong, MJ; Volkening, K	1
Antonini, A; Caioli, S; Curcio, L; Marolda, R; Pieri, M; Severini, C; Zona, C	1
Dengler, R; Döhler, K; Huang, D; Knippenberg, S; Körner, S; Petri, S; Ragancokova, D; Sun, H; Thau, N	1
Cairns, NJ; Ferrario, M; Liberini, P; Moretto, G; Paterlini, M; Pizzi, M; Spano, P; Valerio, A	1
Callewaert, G; Leyssen, M; Robberecht, W; Van Damme, P; Van Den Bosch, L	1
Albo, F; Bernardi, G; Ferrari, F; Longone, P; Mercuri, N; Spalloni, A; Zona, C	1
Albo, F; Bernardi, G; Ferrari, F; Longone, P; Pascucci, T; Puglisi-Allegra, S; Spalloni, A; Zona, C	1
Ito, K; Kanazawa, I; Kawahara, Y; Kwak, S; Sun, H	1
Arneja, A; Crocker, A; David, S; Jeong, GB; Kalb, RG; Mojsilovic-Petrovic, J; Russell, D; Russell, DS	1
Andries, M; Robberecht, W; Van Damme, P; Van Den Bosch, L	1
Fridovich, I; McNamara, JO	1
Brorson, JR; Robberecht, W; Vandenberghe, W	1
Delfs, J; Geula, C; Kuznetsov, D; Saroff, D	1
Aoki, M; Berger, UV; Brown, RH; Danbolt, NC; Hediger, MA; Pasinelli, P; Trotti, D	1
Klaassen, H; Robberecht, W; Van Den Bosch, L; Van Houtte, E; Vandenberghe, W	1
Capobianco, A; Comoletti, D; Mennini, T; Muzio, V; Ravizza, T	1
Bernardi, G; Cavalcanti, S; Costa, N; De Sarro, G; Gaetti, C; Marchetti, C; Mercuri, N; Siniscalchi, A; Zona, C	1
Berchtold, MW; Celio, MR; Klaassen, H; Meijers, B; Missiaen, L; Robberecht, W; Ruehlicke, T; Schwaller, B; Stork, S; Van Den Bosch, L; Van Houtte, E; Vleminckx, V	1
Allaoua, H; Boksa, P; Chaudieu, I; Krieger, C; Perry, TL; Quirion, R	1

Other Studies

22 other study(ies) available for kainic acid and Amyotrophic Lateral Sclerosis

Article	Year
Ablation of C9orf72 together with excitotoxicity induces ALS in rats. The FEBS journal, 2021, Volume: 288, Issue:5 Topics: Amyotrophic Lateral Sclerosis; Animals; C9orf72 Protein; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Gene Deletion; Gene Expression Profiling; Gene Expression Regulation; Gene-Environment Interaction; Golgi Apparatus; Humans; Kainic Acid; Male; Motor Neurons; Nerve Tissue Proteins; Neurogenesis; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Spleen; Transport Vesicles	2021
Effect of intra-cisternal application of kainic acid on the spinal cord and locomotor activity in rats. International journal of clinical and experimental pathology, 2013, Volume: 6, Issue:8 Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Excitatory Amino Acid Agonists; Immunohistochemistry; Kainic Acid; Male; Motor Activity; Neurons; Rats; Rats, Wistar; Spinal Cord	2013
Identifying the primary site of pathogenesis in amyotrophic lateral sclerosis - vulnerability of lower motor neurons to proximal excitotoxicity. Disease models & mechanisms, 2015, Volume: 8, Issue:3 Topics: Amyotrophic Lateral Sclerosis; Animals; Axons; Cell Line; Forelimb; Hindlimb; Kainic Acid; Mice, Inbred C57BL; Motor Activity; Motor Neurons; Nerve Degeneration; Neurotoxins; Spinal Cord	2015
The complement factor C5a receptor is upregulated in NFL-/- mouse motor neurons. Journal of neuroimmunology, 2009, May-29, Volume: 210, Issue:1-2 Topics: Amyotrophic Lateral Sclerosis; Animals; Complement C5a; Disease Models, Animal; Excitatory Amino Acid Agonists; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Neuron Disease; Motor Neurons; Nerve Degeneration; Neurofilament Proteins; Neurotoxins; Receptor, Anaphylatoxin C5a; Up-Regulation	2009
Substance P receptor activation induces downregulation of the AMPA receptor functionality in cortical neurons from a genetic model of Amyotrophic Lateral Sclerosis. Neurobiology of disease, 2011, Volume: 44, Issue:1 Topics: Amyotrophic Lateral Sclerosis; Animals; Blotting, Western; Cell Survival; Cells, Cultured; Cerebral Cortex; Down-Regulation; Electrophysiological Phenomena; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Humans; Immunohistochemistry; Kainic Acid; Mice; Mice, Transgenic; Neurokinin-1 Receptor Antagonists; Neurons; Patch-Clamp Techniques; Receptors, AMPA; Receptors, Neurokinin-1; Synaptic Transmission	2011
Therapeutic potential of N-acetyl-glucagon-like peptide-1 in primary motor neuron cultures derived from non-transgenic and SOD1-G93A ALS mice. Cellular and molecular neurobiology, 2013, Volume: 33, Issue:3 Topics: Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Calcium; Calcium Signaling; Cells, Cultured; Coculture Techniques; Cytosol; Female; Fluorometry; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Humans; Intracellular Space; Kainic Acid; Male; Mice; Mice, Transgenic; Motor Neurons; Neuroprotective Agents; Neurotoxins; Receptors, Glucagon; Superoxide Dismutase	2013
Spinal cord mGlu1a receptors: possible target for amyotrophic lateral sclerosis therapy. Pharmacology, biochemistry, and behavior, 2002, Volume: 73, Issue:2 Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Survival; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Ganglia, Spinal; Glycine; Humans; Immunohistochemistry; Kainic Acid; Motor Neurons; Nerve Degeneration; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord	2002
The AMPA receptor antagonist NBQX prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis. Neuroscience letters, 2003, Jun-05, Volume: 343, Issue:2 Topics: Age Factors; Alanine; Amyotrophic Lateral Sclerosis; Analysis of Variance; Animals; Behavior, Animal; Calcium; Cells, Cultured; Disease Models, Animal; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Forelimb; Glycine; Hand Strength; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Neurons; Psychomotor Performance; Quinoxalines; Receptors, AMPA	2003
Cu/Zn-superoxide dismutase (GLY93-->ALA) mutation alters AMPA receptor subunit expression and function and potentiates kainate-mediated toxicity in motor neurons in culture. Neurobiology of disease, 2004, Volume: 15, Issue:2 Topics: Alanine; Amyotrophic Lateral Sclerosis; Animals; Cells, Cultured; Drug Resistance; Fetus; Genetic Predisposition to Disease; Glycine; Kainic Acid; Membrane Potentials; Mice; Mice, Transgenic; Motor Neurons; Mutation; Neurotoxins; Protein Subunits; Receptors, AMPA; RNA, Messenger; Superoxide Dismutase; Synaptic Transmission	2004
Altered vulnerability to kainate excitotoxicity of transgenic-Cu/Zn SOD1 neurones. Neuroreport, 2004, Nov-15, Volume: 15, Issue:16 Topics: Amyotrophic Lateral Sclerosis; Analysis of Variance; Animals; Asparagine; Calcium Channel Blockers; Cell Count; Cell Survival; Cells, Cultured; Cerebral Cortex; Cobalt; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Female; Glial Fibrillary Acidic Protein; Glutamic Acid; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Transgenic; Motor Neurons; Neurotoxins; Nifedipine; Phosphopyruvate Hydratase; Sodium Channel Blockers; Spinal Cord; Superoxide Dismutase; Tetrodotoxin; Time Factors	2004
Slow and selective death of spinal motor neurons in vivo by intrathecal infusion of kainic acid: implications for AMPA receptor-mediated excitotoxicity in ALS. Journal of neurochemistry, 2006, Volume: 98, Issue:3 Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Death; Excitatory Amino Acid Agonists; Injections, Spinal; Kainic Acid; Male; Motor Neurons; Rats; Rats, Inbred F344; Rats, Wistar; Receptors, AMPA; Spinal Cord; Time Factors	2006
Protecting motor neurons from toxic insult by antagonism of adenosine A2a and Trk receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Sep-06, Volume: 26, Issue:36 Topics: Adenosine A2 Receptor Antagonists; Amyotrophic Lateral Sclerosis; Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Kainic Acid; Motor Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptor, Adenosine A2A	2006
Ivermectin inhibits AMPA receptor-mediated excitotoxicity in cultured motor neurons and extends the life span of a transgenic mouse model of amyotrophic lateral sclerosis. Neurobiology of disease, 2007, Volume: 25, Issue:1 Topics: Adenosine Triphosphate; Amyotrophic Lateral Sclerosis; Animals; Cell Death; Cell Survival; Cells, Cultured; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hypoglycemia; Hypoxia, Brain; Ivermectin; Kainic Acid; Longevity; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Neurons; Pyridoxal Phosphate; Rats; Receptors, AMPA; Receptors, Purinergic P2; Superoxide Dismutase; Superoxide Dismutase-1; Triazines	2007
Human genetics. Did radicals strike Lou Gehrig? Nature, 1993, Mar-04, Volume: 362, Issue:6415 Topics: Amyotrophic Lateral Sclerosis; Calcium Channels; Humans; Kainic Acid; Models, Biological; Motor Neurons; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Superoxide Dismutase; Superoxides	1993
AMPA receptor calcium permeability, GluR2 expression, and selective motoneuron vulnerability. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Jan-01, Volume: 20, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amyotrophic Lateral Sclerosis; Animals; Calcium; Cell Survival; Cells, Cultured; Excitatory Amino Acid Agonists; Gene Expression; Kainic Acid; Motor Neurons; Nerve Degeneration; Neurotoxins; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord	2000
Selective vulnerability of spinal cord motor neurons to non-NMDA toxicity. Neuroreport, 2000, Apr-07, Volume: 11, Issue:5 Topics: Acetylcholinesterase; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Cell Count; Cell Size; Cell Survival; Cells, Cultured; Excitatory Amino Acid Agonists; Immunohistochemistry; Kainic Acid; Motor Neurons; Neurofilament Proteins; Neurotoxins; Quisqualic Acid; Rats; Receptors, Glutamate; Spinal Cord	2000
Amyotrophic lateral sclerosis-linked glutamate transporter mutant has impaired glutamate clearance capacity. The Journal of biological chemistry, 2001, Jan-05, Volume: 276, Issue:1 Topics: Amino Acid Substitution; Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Animals; ATP-Binding Cassette Transporters; Biological Transport; Cell Membrane; COS Cells; Cytoplasm; Electric Conductivity; Fluorescent Antibody Technique; Genes, Dominant; Glutamic Acid; Glycosylation; Humans; Kainic Acid; Microinjections; Mutation; Oocytes; RNA, Complementary; Sodium Glutamate; Transfection; Xenopus laevis	2001
Ca(2+)-permeable AMPA receptors and selective vulnerability of motor neurons. Journal of the neurological sciences, 2000, Nov-01, Volume: 180, Issue:1-2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amyotrophic Lateral Sclerosis; Animals; Benzodiazepines; Calcium Channels; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Kainic Acid; Motor Neurons; Neurotoxins; Nifedipine; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, AMPA; Spider Venoms	2000
Nitric oxide produced by non-motoneuron cells enhances rat embryonic motoneuron sensitivity to excitotoxins: comparison in mixed neuron/glia or purified cultures. Journal of the neurological sciences, 2001, Nov-15, Volume: 192, Issue:1-2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amyotrophic Lateral Sclerosis; Animals; Anterior Horn Cells; Cell Communication; Cell Differentiation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Glycine; Kainic Acid; Magnesium; N-Methylaspartate; Neuroglia; Neurotoxins; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate	2001
Kainate-induced currents in rat cortical neurons in culture are modulated by riluzole. Synapse (New York, N.Y.), 2002, Mar-15, Volume: 43, Issue:4 Topics: Amyotrophic Lateral Sclerosis; Animals; Cells, Cultured; Cerebral Cortex; Epilepsy; Excitatory Amino Acid Agonists; Fetus; Ion Channels; Kainic Acid; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Riluzole	2002
Protective effect of parvalbumin on excitotoxic motor neuron death. Experimental neurology, 2002, Volume: 174, Issue:2 Topics: Amyotrophic Lateral Sclerosis; Animals; Blotting, Western; Calcium; Calcium Signaling; Cell Death; Cells, Cultured; Cytoprotection; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Agonists; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Neurons; Neurotoxins; Organ Specificity; Parvalbumins; Phenotype; Posterior Horn Cells; Receptors, AMPA	2002
Excitatory amino acid receptors in human spinal cord. Evaluation in amyotrophic lateral sclerosis patients. Annals of the New York Academy of Sciences, 1992, May-11, Volume: 648 Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Humans; Kainic Acid; Middle Aged; Neurotoxins; Oxadiazoles; Quisqualic Acid; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reference Values; Spinal Cord; Tritium	1992