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kainic acid and Akinetic-Rigid Variant of Huntington Disease

kainic acid has been researched along with Akinetic-Rigid Variant of Huntington Disease in 76 studies

Research

Studies (76)

Timeframe	Studies, this research(%)	All Research%
pre-1990	53 (69.74)	18.7374
1990's	15 (19.74)	18.2507
2000's	7 (9.21)	29.6817
2010's	1 (1.32)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Mazurová, Y; Osterreicher, J; Valousková, V	1
Barton, SJ; Bunner, KD; Dorner, JL; Gaither, TW; Klein, EL; Miller, BR; Rebec, GV	1
Choi, DW; Lee, CS; Macdonald, ME; Moss, JL; Revilla, FJ; Snider, BJ; Wheeler, VC	1
Guidetti, P; Pellicciari, R; Sapko, MT; Schwarcz, R; Tagle, DA; Yu, P	1
McLin, JP; Steward, O; Thompson, LM	1
Ciliax, BJ; Pan, HS; Penney, JB; Young, AB	1
Arnason, BG; Beutler, BA; Noronha, AB; Poon, MM	1
Johnston, GA; Sanberg, PR	1
McGeer, EG; McGeer, PL; Wong, PT	1
Carter, CJ	2
Bird, ED; Hefti, F; Melamed, E	1
Levin, SL; Sytinskiĭ, IA	1
Köhler, C; Schwarcz, R	1
Coyle, JT; Deckel, AW; Robinson, RG; Sanberg, PR	1
Hunter, JF; Rieke, GK; Scarfe, AD	1
Bioulac, B; Doudet, D; Gross, C	1
Butterfield, DA; Markesbery, WR	1
Brennan, MJ; Kramer, S; Metz, J; van der Westhuyzen, J	1
McGeer, EG; McGeer, PL	3
Deshmukh, P; Morelli, M; Schoemaker, H; Yamamura, HI	1
Finch, CE	1
Krammer, EB	1
Kimura, H; McGeer, EG; McGeer, PL	1
Bird, ED; Coyle, JT; London, ED; Yamamura, HI	1
Bernheimer, H; Higatsberger, MR; Hornykiewicz, O; Shannak, KS; Sperk, G	1
Choi, D; Gottron, F; Turetsky, D	1
Folstein, SE; Hedreen, JC; Peyser, CE; Ross, CA; Wagster, MV	1
Albin, RL; Kremer, B; Tallaksen-Greene, SJ	1
Dodd, PR; Johnston, GA; Leong, DK	1
Akiyama, A; Nakazato, T	1
Bernardi, G; Calabresi, P; Centonze, D; Gubellini, P; Marfia, GA; Pisani, A; Sancesario, G	1
Alberch, J; Arenas, E; Canals, JM; Checa, N; Marco, S; Michels, A; Pérez-Navarro, E	1
Leavens, W; Morton, AJ	1
Akerud, P; Alberch, J; Arenas, E; Canals, JM; Checa, N; Marco, S; Michels, A; Pérez-Navarro, E; Tolosa, E	1
Giordano, M; Mejía-Viggiano, MC	1
Fibiger, HC; Mason, ST; Sanberg, PR	1
Fibiger, HC; Lehmann, J; Sanberg, PR	2
Fibiger, HC; Mason, ST	2
Coyle, JT	1
Carolei, A; Del Castillo, G	1
de Gubareff, T; Olney, JW	1
McGeer, EG; McGeer, PL; Singh, K	1
Friedle, NM; Kelly, PH; Moore, KE	1
Bennett, JP; Coyle, JT; Schwarcz, R	1
Coyle, JT; Harris, LW; Heyl, WC; London, ED	1
Beaumont, K; Bird, ED; Fields, JZ; Maurin, Y; Reisine, TD; Spokes, E; Yamamura, HI	1
Fibiger, HC; Sanberg, PR	1
Henke, H	1
Borison, RL; Diamond, BI	1
McGeer, EG; Singh, EA	1
Arregui, A; Emson, PC; Spokes, EG	1
Bennett, JP; Campochiaro, P; Coyle, JT; Schwarcz, R	1
Cotton, P	1
Dure, LS; Penney, JB; Young, AB	1
Dodd, PR; Johnston, GA; Morrison, MM; Ruwoldt, A; Smith, AI; Walls, RS; Watson, WE	1
Beal, MF; Ferrante, RJ; Kowall, NW; Swartz, KJ	1
Ford, LM; Giordano, M; Sanberg, PR; Shipley, MT	1
Kanazawa, I	1
Norman, AB; Pratt, RG; Samaratunga, RC; Sanberg, PR; Thomas, SR	1
Jhamandas, K; Ruzicka, BB	1
Giòrdano, M; Hagenmeyer-Houser, SH; Henault, MA; Nash, DR; Ragozzino, ME; Sanberg, PR	1
Gray, PN; May, PC	1
Beal, MF; Burd, GD; Landis, DM; Marshall, PE; Martin, JB	1
Choi, DW; Koh, JY; Peters, S	1
Bioulac, B; Doudet, D; Gross, C; Pouchot, C	1
Matyja, E	1
Allen, GS; Huang, S; Tulipan, N; Whetsell, WO	1
Deckel, AW; Henault, MA; Sanberg, PR	1
Marasigan, SM; Miyoshi, K; Sato, M	1
Go, KG; Gramsbergen, JB; Korf, J; Prenen, GH	1
Giordano, M; Hagenmeyer-Houser, SH; Sanberg, PR	1

Reviews

9 review(s) available for kainic acid and Akinetic-Rigid Variant of Huntington Disease

Article	Year
Glutamate and Huntington's disease. The Medical journal of Australia, 1981, Oct-31, Volume: 2, Issue:9 Topics: Age Factors; Animals; Basal Ganglia; Glutamates; Humans; Huntington Disease; Kainic Acid; Models, Biological; Neurons; Neurotransmitter Agents; Psychotropic Drugs; Rats; Receptors, Dopamine; Synapses	1981
[Toxic action of kainic acid as a model of Huntington chorea and epilepsy (review)]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1983, Volume: 83, Issue:5 Topics: Animals; Anticonvulsants; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Drug Interactions; gamma-Aminobutyric Acid; Hippocampus; Humans; Huntington Disease; Kainic Acid; Pyrrolidines; Rats; Seizures; Substantia Nigra	1983
Huntington's disease: a generalized membrane defect. Life sciences, 1981, Mar-09, Volume: 28, Issue:10 Topics: Animals; Blood Platelets; Cell Membrane; Electron Spin Resonance Spectroscopy; Erythrocyte Aging; Erythrocyte Membrane; Erythrocytes; gamma-Aminobutyric Acid; Humans; Huntington Disease; Kainic Acid; Lipid Bilayers; Lymphocytes; Membrane Lipids; Membrane Proteins; Neurons; Rats; Skin	1981
Kainic acid: The neurotoxic breakthrough. Critical reviews in toxicology, 1982, Volume: 10, Issue:1 Topics: Animals; Epilepsy; Hippocampus; Huntington Disease; Kainic Acid; Neurotoxins; Pyrrolidines; Receptors, Cell Surface; Receptors, Glutamate; Retina	1982
The relationships of aging changes in the basal ganglia to manifestations of Huntington's chorea. Annals of neurology, 1980, Volume: 7, Issue:5 Topics: Adenylyl Cyclases; Aging; Animals; Basal Ganglia; Cell Survival; Disease Models, Animal; Dopamine; Humans; Huntington Disease; Kainic Acid; Mice; Mice, Inbred CBA; Rats; Receptors, Dopamine; Species Specificity; Substantia Nigra	1980
[Recent neurobiological and related pharmaco-therapeutic acquisitions in Huntington's chorea]. La Clinica terapeutica, 1979, Sep-30, Volume: 90, Issue:6 Topics: Amphetamine; Antipsychotic Agents; Brain; Butyrophenones; gamma-Aminobutyric Acid; Humans; Huntington Disease; Kainic Acid; Levodopa; Lithium; Neurotransmitter Agents; Phenothiazines; Sympatholytics; Tetrabenazine	1979
Use of the neurotoxic agents kainic acid and tetanus toxin in the extrapyramidal system. Advances in cytopharmacology, 1979, Volume: 3 Topics: Animals; Brain; Cerebellum; Extrapyramidal Tracts; gamma-Aminobutyric Acid; Hippocampus; Huntington Disease; Hydroxydopamines; Hypothalamo-Hypophyseal System; Kainic Acid; Neurotoxins; Pyrrolidines; Rats; Retina; Tetanus Toxin	1979
[Model of choreic movement in monkey--contribution for understanding the mechanism of chorea in Huntington's disease]. Jikken dobutsu. Experimental animals, 1990, Volume: 39, Issue:2 Topics: Animals; Disease Models, Animal; Dopamine; Haplorhini; Huntington Disease; Kainic Acid; Levodopa	1990
Cation shifts and excitotoxins in Alzheimer and Huntington disease and experimental brain damage. Progress in brain research, 1986, Volume: 70 Topics: Aged; Alzheimer Disease; Amino Acids; Animals; Brain; Brain Diseases; Calcium; Cations; gamma-Aminobutyric Acid; Humans; Huntington Disease; Kainic Acid; Middle Aged; Neurotoxins; Tetrodotoxin	1986

Other Studies

67 other study(ies) available for kainic acid and Akinetic-Rigid Variant of Huntington Disease

Article	Year
[An animal model of Huntington's disease: the development of histopathological changes within the neurotoxic lesions of the striatum in long-term surviving rats]. Acta medica (Hradec Kralove). Supplementum, 2002, Volume: 45, Issue:2 Topics: Animals; Corpus Striatum; Disease Models, Animal; Huntington Disease; Ibotenic Acid; Kainic Acid; Neurotoxins; Rats; Rats, Long-Evans	2002
Up-regulation of GLT1 reverses the deficit in cortically evoked striatal ascorbate efflux in the R6/2 mouse model of Huntington's disease. Journal of neurochemistry, 2012, Volume: 121, Issue:4 Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Aspartic Acid; Ceftriaxone; Cerebral Cortex; Corpus Striatum; Electric Stimulation; Excitatory Amino Acid Transporter 2; Extracellular Fluid; Genotype; Huntington Disease; Kainic Acid; Male; Mice; Mice, Transgenic; Microinjections; Transcription, Genetic; Up-Regulation	2012
Neocortical neurons cultured from mice with expanded CAG repeats in the huntingtin gene: unaltered vulnerability to excitotoxins and other insults. Neuroscience, 2003, Volume: 120, Issue:3 Topics: Animals; Apoptosis; Cell Culture Techniques; Gene Expression; Genotype; Huntingtin Protein; Huntington Disease; Immunoblotting; Immunohistochemistry; Kainic Acid; Mice; Mice, Transgenic; N-Methylaspartate; Neocortex; Nerve Tissue Proteins; Neurons; Neurotoxins; Nuclear Proteins; Oxidative Stress; Peptides; Trinucleotide Repeat Expansion	2003
Endogenous kynurenate controls the vulnerability of striatal neurons to quinolinate: Implications for Huntington's disease. Experimental neurology, 2006, Volume: 197, Issue:1 Topics: Animals; Brain Chemistry; Excitatory Amino Acid Agonists; Huntington Disease; Kainic Acid; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Mice; Mice, Knockout; Microinjections; Neostriatum; Neurons; Quinolinic Acid; Transaminases	2006
Differential susceptibility to striatal neurodegeneration induced by quinolinic acid and kainate in inbred, outbred and hybrid mouse strains. The European journal of neuroscience, 2006, Volume: 24, Issue:11 Topics: Animals; Chimera; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance; Genetic Predisposition to Disease; Huntington Disease; Kainic Acid; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Mice, Inbred ICR; Nerve Degeneration; Neurons; Neurotoxins; Phenotype; Quinolinic Acid; Species Specificity	2006
GABA and benzodiazepine receptors in basal ganglia function. Neuroscience letters, 1984, Jun-29, Volume: 47, Issue:3 Topics: Animals; Basal Ganglia; Caudate Nucleus; Corpus Striatum; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Huntington Disease; Kainic Acid; Neural Inhibition; Neural Pathways; Putamen; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Opioid; Substantia Nigra; Synaptic Transmission	1984
The absence of unique kainic acid-like molecules in urine, serum, and CSF from Huntington's disease patients. Journal of the neurological sciences, 1981, Volume: 51, Issue:3 Topics: Animals; Binding, Competitive; Brain; Glutamates; Glutamic Acid; Huntington Disease; Kainic Acid; Ketoglutaric Acids; Male; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Kainic Acid	1981
Effects of kainic acid injection and cortical lesion on ornithine and aspartate aminotransferases in rat striatum. Journal of neuroscience research, 1982, Volume: 8, Issue:4 Topics: Animals; Aspartate Aminotransferases; Corpus Striatum; Frontal Lobe; Glutamates; Glutamic Acid; Humans; Huntington Disease; Kainic Acid; Muridae; Neural Pathways; Ornithine-Oxo-Acid Transaminase; Parietal Lobe; Pyrrolidines; Transaminases	1982
Increased alanine aminotransferase activity in the Huntington's disease putamen. Journal of the neurological sciences, 1984, Volume: 66, Issue:1 Topics: Alanine Transaminase; Animals; Corpus Striatum; Cytosol; Glutamate-Ammonia Ligase; Humans; Huntington Disease; Kainic Acid; Male; Middle Aged; Mitochondria; Putamen; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains	1984
Huntington chorea is not associated with hyperactivity of nigrostriatal dopaminergic neurons: studies in postmortem tissues and in rats with kainic acid lesions. Neurology, 1982, Volume: 32, Issue:6 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Diseases; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Humans; Huntington Disease; Kainic Acid; Male; Middle Aged; Neurons; Rats; Rats, Inbred Strains	1982
Differential vulnerability of central neurons of the rat to quinolinic acid. Neuroscience letters, 1983, Jul-15, Volume: 38, Issue:1 Topics: Animals; Brain; Corpus Striatum; Diencephalon; Epilepsy, Temporal Lobe; Hippocampus; Huntington Disease; Ibotenic Acid; Kainic Acid; Male; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Telencephalon	1983
Reversal of long-term locomotor abnormalities in the kainic acid model of Huntington's disease by day 18 fetal striatal implants. European journal of pharmacology, 1983, Sep-30, Volume: 93, Issue:3-4 Topics: Animals; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Female; Fetus; Huntington Disease; Kainic Acid; Locomotion; Pregnancy; Rats; Rats, Inbred Strains	1983
Reduced GABA transaminase activity in the Huntington's disease putamen. Neuroscience letters, 1984, Aug-10, Volume: 48, Issue:3 Topics: 4-Aminobutyrate Transaminase; Animals; Choline O-Acetyltransferase; Glutamate Decarboxylase; Humans; Huntington Disease; Kainic Acid; Putamen; Rats; Reference Values	1984
L-pyroglutamate: an alternate neurotoxin for a rodent model of Huntington's disease. Brain research bulletin, 1984, Volume: 13, Issue:3 Topics: Animals; Basal Ganglia; Basal Ganglia Diseases; Corpus Striatum; Disease Models, Animal; Huntington Disease; Kainic Acid; Male; Mice; Microscopy, Electron; Pyrrolidinones; Pyrrolidonecarboxylic Acid	1984
[Activity of dopaminergic neurons of the substantia nigra following lesions of the neostriatum by kainic acid]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1984, Volume: 178, Issue:3 Topics: Action Potentials; Animals; Caudate Nucleus; Disease Models, Animal; Dopamine; Electrophysiology; Huntington Disease; Kainic Acid; Male; Neurons; Putamen; Pyrrolidines; Rats; Rats, Inbred Strains; Substantia Nigra	1984
Neurotoxicity of folates: implications for vitamin B12 deficiency and Huntington's chorea. Medical hypotheses, 1981, Volume: 7, Issue:7 Topics: Animals; Brain; Chemical Phenomena; Chemistry; Chiroptera; Folic Acid; gamma-Aminobutyric Acid; Humans; Huntington Disease; Kainic Acid; Models, Biological; Rats; Receptors, Cell Surface; Receptors, Kainic Acid; Tetrahydrofolates; Vitamin B 12 Deficiency	1981
[3H]Ro5-4864 benzodiazepine binding in the kainate lesioned striatum and Huntington's diseased basal ganglia. Brain research, 1982, Sep-30, Volume: 248, Issue:2 Topics: Aged; Animals; Benzodiazepinones; Binding Sites; Corpus Striatum; Flunitrazepam; Humans; Huntington Disease; Kainic Acid; Male; Middle Aged; Neuroglia; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A	1982
Anterograde and transsynaptic degeneration 'en cascade' in basal ganglia induced by intrastriatal injection of kainic acid: an animal analogue of Huntington's disease. Brain research, 1980, Aug-25, Volume: 196, Issue:1 Topics: Acetylcholinesterase; Animals; Basal Ganglia; Corpus Striatum; Disease Models, Animal; Female; Globus Pallidus; Huntington Disease; Kainic Acid; Male; Nerve Degeneration; Neurons; Pyrrolidines; Rats; Substantia Nigra; Synapses	1980
Metabolic alterations in an animal model of Huntington's disease using the 14C-deoxyglucose method. Journal of neural transmission. Supplementum, 1980, Issue:16 Topics: Animals; Autoradiography; Deoxy Sugars; Deoxyglucose; Disease Models, Animal; Huntington Disease; Kainic Acid; Male; Rats	1980
Decreased receptor-binding sites for kainic acid in brains of patients with Huntington's disease. Biological psychiatry, 1981, Volume: 16, Issue:2 Topics: Adult; Animals; Binding Sites; Brain Chemistry; Caudate Nucleus; Female; Frontal Lobe; Humans; Huntington Disease; Kainic Acid; Male; Middle Aged; Postmortem Changes; Putamen; Pyrrolidines; Rats; Receptors, Drug	1981
Striatal ganglioside levels in the rat following kainic acid lesions: comparison with Huntington's disease. Experimental brain research, 1981, Volume: 44, Issue:1 Topics: Animals; Brain Chemistry; Corpus Striatum; Disease Models, Animal; Gangliosides; Humans; Huntington Disease; Kainic Acid; Male; Pyrrolidines; Rats; Tissue Distribution	1981
SMI-32 antibody against non-phosphorylated neurofilaments identifies a subpopulation of cultured cortical neurons hypersensitive to kainate toxicity. Neuroscience letters, 1995, Jul-14, Volume: 194, Issue:1-2 Topics: Alzheimer Disease; Animals; Antibodies, Monoclonal; Cell Death; Cells, Cultured; Cerebral Cortex; Huntington Disease; Hypersensitivity; Immunohistochemistry; Kainic Acid; Mice; Mice, Inbred Strains; Neurofilament Proteins; Neurons	1995
Selective loss of [3H]kainic acid and [3H]AMPA binding in layer VI of frontal cortex in Huntington's disease. Experimental neurology, 1994, Volume: 127, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Autoradiography; Frontal Lobe; Humans; Huntington Disease; Kainic Acid; Middle Aged; Neurons; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Reference Values; Tritium	1994
AMPA and NMDA binding sites in the hypothalamic lateral tuberal nucleus: implications for Huntington's disease. Neurology, 1993, Volume: 43, Issue:8 Topics: Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Glutamates; Glutamic Acid; Humans; Huntington Disease; Hypothalamic Area, Lateral; Ibotenic Acid; Kainic Acid; Middle Aged; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate	1993
Brain extracts containing a Huntington disease antigen inhibit [3H]kainate binding and block synaptosomal amino acid transport. Neurochemistry international, 1993, Volume: 23, Issue:2 Topics: Amino Acids; Animals; Antigens; Biological Transport; Brain; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; Huntington Disease; Kainic Acid; Rats; Rats, Sprague-Dawley; Synaptosomes; Tissue Extracts; Tritium	1993
In vivo electrochemical measurement of the long-lasting release of dopamine and serotonin induced by intrastriatal kainic acid. Journal of neurochemistry, 1997, Volume: 69, Issue:5 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Ascorbic Acid; Circadian Rhythm; Corpus Striatum; Dopamine; Electrochemistry; Huntington Disease; Kainic Acid; Kinetics; Male; Microinjections; Rats; Rats, Wistar; Serotonin; Time Factors	1997
Striatal spiny neurons and cholinergic interneurons express differential ionotropic glutamatergic responses and vulnerability: implications for ischemia and Huntington's disease. Annals of neurology, 1998, Volume: 43, Issue:5 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Cholinergic Fibers; Corpus Striatum; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Huntington Disease; Interneurons; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurotoxins; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission	1998
Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 after excitotoxicity in a rat model of Huntington's disease. Neurobiology of disease, 1998, Volume: 5, Issue:5 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cycloleucine; Excitatory Amino Acid Agonists; Huntington Disease; Kainic Acid; Male; Neostriatum; Nerve Growth Factors; Neuroprotective Agents; Neurotrophin 3; Quinolinic Acid; Rats; Rats, Sprague-Dawley; RNA, Messenger	1998
Mice transgenic for the human Huntington's disease mutation have reduced sensitivity to kainic acid toxicity. Brain research bulletin, 2000, May-01, Volume: 52, Issue:1 Topics: Animals; Brain; Cell Nucleus; Drug Resistance; Hindlimb; Hippocampus; Humans; Huntington Disease; Inclusion Bodies; Kainic Acid; Mice; Mice, Transgenic; Mutation; Neurons; Pyramidal Cells; Seizures; Survival Analysis; Time Factors	2000
Expression of brain-derived neurotrophic factor in cortical neurons is regulated by striatal target area. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Jan-01, Volume: 21, Issue:1 Topics: 3T3 Cells; Animals; Axonal Transport; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Colchicine; Corpus Striatum; Disease Models, Animal; Fibroblasts; Fluorescent Dyes; Hippocampus; Huntington Disease; In Situ Hybridization; Kainic Acid; Male; Mice; Microinjections; Neural Pathways; Neurons; Nitro Compounds; Propionates; Quinolinic Acid; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; RNA, Messenger; Stilbamidines; Up-Regulation	2001
Gender differences in spontaneous and MK-801-induced activity after striatal lesions. Brain research bulletin, 2001, Volume: 56, Issue:6 Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Huntington Disease; Hyperkinesis; Kainic Acid; Male; Motor Activity; Neostriatum; Neurons; Neurotoxins; Rats; Rats, Wistar; Sex Characteristics	2001
Kainic acid lesions of the striatum dissociate amphetamine and apomorphine stereotypy: similarities to Huntingdon's chorea. Science (New York, N.Y.), 1978, Jul-28, Volume: 201, Issue:4353 Topics: Animals; Apomorphine; Behavior; Choline O-Acetyltransferase; Corpus Striatum; Dextroamphetamine; Disease Models, Animal; Glutamate Decarboxylase; Humans; Huntington Disease; Kainic Acid; Male; Nucleus Accumbens; Pyrrolidines; Rats; Stereotyped Behavior; Tyrosine 3-Monooxygenase	1978
Impaired learning and memory after kainic acid lesions of the striatum: a behavioral model of Huntington's disease. Brain research, 1978, Jun-30, Volume: 149, Issue:2 Topics: Animals; Avoidance Learning; Cerebral Cortex; Choline O-Acetyltransferase; Corpus Striatum; Disease Models, Animal; Glutamate Decarboxylase; Huntington Disease; Kainic Acid; Male; Memory; Mental Recall; Motor Activity; Pyrrolidines; Rats; Retention, Psychology; Tyrosine 3-Monooxygenase	1978
Kainic acid lesions of the striatum: behavioural sequalae similar to Huntington's chorea. Brain research, 1978, Oct-27, Volume: 155, Issue:2 Topics: Animals; Apomorphine; Cerebral Cortex; Choline O-Acetyltransferase; Corpus Striatum; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamate Decarboxylase; Habituation, Psychophysiologic; Humans; Huntington Disease; Kainic Acid; Male; Motor Activity; Neurons; Nucleus Accumbens; Pyrrolidines; Rats; Stereotyped Behavior; Tyrosine 3-Monooxygenase	1978
Intracerebral injections of kainic acid and tetanus toxin: possible models for the signs of chorea and dystonia. Advances in neurology, 1978, Volume: 21 Topics: Animals; Biogenic Amines; Brain Chemistry; Choline O-Acetyltransferase; Corpus Striatum; Disease Models, Animal; Dystonia Musculorum Deformans; Glutamate Decarboxylase; Humans; Huntington Disease; Kainic Acid; Pyrrolidines; Rats; Substantia Nigra; Tetanus Toxin; Thalamus; Tyrosine 3-Monooxygenase	1978
Kainic acid lesions of the striatum in rats mimic the spontaneous motor abnormalities of Huntington's Disease. Neuropharmacology, 1979, Volume: 18, Issue:4 Topics: Animals; Behavior, Animal; Choline O-Acetyltransferase; Corpus Striatum; Disease Models, Animal; Glutamate Decarboxylase; Huntington Disease; Kainic Acid; Male; Motor Activity; Pimozide; Pyrrolidines; Rats; Tyrosine 3-Monooxygenase	1979
An animal model for Huntington's disease. Biological psychiatry, 1979, Volume: 14, Issue:2 Topics: Animals; Choline O-Acetyltransferase; Corpus Striatum; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Huntington Disease; Kainic Acid; Nerve Degeneration; Neural Pathways; Rats; Receptors, Neurotransmitter; Substantia Nigra; Tyrosine 3-Monooxygenase	1979
Glutamate neurotoxicity and Huntington's chorea. Nature, 1978, Feb-09, Volume: 271, Issue:5645 Topics: Animals; Corpus Striatum; gamma-Aminobutyric Acid; Glutamates; Huntington Disease; Injections; Kainic Acid; Male; Neurons; Rats	1978
Kainate-induced degeneration of neostriatal neurons: dependency upon corticostriatal tract. Brain research, 1978, Jan-13, Volume: 139, Issue:2 Topics: Animals; Cerebral Cortex; Corpus Striatum; Efferent Pathways; Glutamates; Huntington Disease; In Vitro Techniques; Kainic Acid; Male; Nerve Degeneration; Pyrrolidines; Rats	1978
Regional brain atrophy and reductions in glutamate release and uptake after intrastriatal kainic acid. British journal of pharmacology, 1978, Volume: 63, Issue:1 Topics: Animals; Brain; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dopamine; Glutamate Decarboxylase; Glutamates; Huntington Disease; Kainic Acid; Male; Pyrrolidines; Rats	1978
Inhibitors of GABA metabolism: implications for Huntington's disease. Annals of neurology, 1977, Volume: 2, Issue:4 Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Aminocaproic Acid; Animals; Caudate Nucleus; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Huntington Disease; Kainic Acid; Male; Nerve Degeneration; Rats; Substantia Nigra; Transaminases; Valproic Acid	1977
Effect of 2-dimethylaminoethanol in kainate-lesioned rat striatum: anomaly in the radioenzymatic assay of acetylcholine. Communications in psychopharmacology, 1978, Volume: 2, Issue:4 Topics: Acetylcholine; Animals; Brain Chemistry; Choline; Chromatography, Gas; Corpus Striatum; Deanol; Disease Models, Animal; Ethanolamines; Huntington Disease; Kainic Acid; Male; Phosphorus Radioisotopes; Pyrrolidines; Rats	1978
Huntington's disease and its animal model: alterations in kainic acid binding. Life sciences, 1979, Feb-26, Volume: 24, Issue:9 Topics: Animals; Binding Sites; Caudate Nucleus; Choline O-Acetyltransferase; Corpus Striatum; Disease Models, Animal; Huntington Disease; Kainic Acid; Kinetics; Male; Putamen; Pyrrolidines; Rats; Synaptic Membranes; Time Factors	1979
Sedative effects of apomorphine in an animal model of Huntington's disease. Archives of neurology, 1979, Volume: 36, Issue:6 Topics: Animals; Apomorphine; Corpus Striatum; Dextroamphetamine; Disease Models, Animal; Humans; Huntington Disease; Kainic Acid; Male; Motor Activity; Rats; Receptors, Dopamine; Stereotyped Behavior	1979
Body weight, feeding, and drinking behaviors in rats with kainic acid-induced lesions of striatal neurons--with a note on body weight symptomatology in Huntington's disease. Experimental neurology, 1979, Volume: 66, Issue:3 Topics: Animals; Body Weight; Brain Diseases; Corpus Striatum; Disease Models, Animal; Drinking Behavior; Feeding Behavior; Huntington Disease; Kainic Acid; Male; Pyrrolidines; Rats	1979
Kainic acid binding in human caudate nucleus: effect of Huntington's disease. Neuroscience letters, 1979, Volume: 14, Issue:2-3 Topics: Binding, Competitive; Caudate Nucleus; Glutamates; Humans; Huntington Disease; Kainic Acid; Molecular Conformation; Pyrrolidines; Stereoisomerism	1979
Kainic acid animal model predicts therapeutic agents in Huntington's chorea. Transactions of the American Neurological Association, 1979, Volume: 104 Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Huntington Disease; Kainic Acid; Male; Pyrrolidines; Rats	1979
Angiotensin converting enzyme in kainic acid--injected striata. Annals of neurology, 1978, Volume: 4, Issue:1 Topics: Animals; Choline O-Acetyltransferase; Corpus Striatum; Glutamate Decarboxylase; Huntington Disease; Injections; Kainic Acid; Male; Peptidyl-Dipeptidase A; Pyrrolidines; Rats	1978
Angiotensin-converting enzyme in substantia nigra: reduction of activity in Huntington's disease and after intrastriatal kainic acid in rats. European journal of pharmacology, 1978, Nov-01, Volume: 52, Issue:1 Topics: Animals; Caudate Nucleus; Corpus Striatum; Humans; Huntington Disease; Kainic Acid; Male; Nucleus Accumbens; Peptidyl-Dipeptidase A; Putamen; Pyrrolidines; Rats; Substantia Nigra	1978
Clinical, neuropathologic and pharmacologic aspects of Huntington's disease: correlates with a new animal model. Progress in neuro-psychopharmacology, 1977, Volume: 1, Issue:1-2 Topics: Animals; Brain; Corpus Striatum; Disease Models, Animal; gamma-Aminobutyric Acid; Humans; Huntington Disease; Kainic Acid; Pyrrolidines; Rats; Receptors, Cholinergic; Substantia Nigra; Synaptic Transmission	1977
Neuroscientists begin to piece together more parts of Huntington's disease puzzle. JAMA, 1992, Dec-16, Volume: 268, Issue:23 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biomarkers; Brain Chemistry; Disease Models, Animal; Fibroblast Growth Factors; Humans; Huntington Disease; Ibotenic Acid; Kainic Acid; Lactates; Lactic Acid; Rats	1992
Excitatory amino acid binding sites in the caudate nucleus and frontal cortex of Huntington's disease. Annals of neurology, 1991, Volume: 30, Issue:6 Topics: Adolescent; Adult; Age Factors; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Binding, Competitive; Caudate Nucleus; Cell Death; Child; Dizocilpine Maleate; Frontal Lobe; Glycine; Humans; Huntington Disease; Ibotenic Acid; Kainic Acid; Middle Aged; N-Methylaspartate; Phencyclidine; Receptors, AMPA; Receptors, Glutamate; Receptors, Glycine; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine	1991
The interaction of a Huntington disease factor with receptors for the neurotoxin kainic acid. Metabolic brain disease, 1991, Volume: 6, Issue:4 Topics: Animals; Brain; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Striatum; Humans; Huntington Disease; In Vitro Techniques; Kainic Acid; Leukocytes; Rats; Receptors, Kainic Acid; Receptors, Neurotransmitter; Spectrophotometry, Ultraviolet; Subcellular Fractions; Synaptic Membranes	1991
Chronic quinolinic acid lesions in rats closely resemble Huntington's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1991, Volume: 11, Issue:6 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atrophy; Biogenic Amines; Cerebral Cortex; Choline O-Acetyltransferase; Corpus Striatum; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamates; Huntington Disease; Ibotenic Acid; Kainic Acid; Male; Mesencephalon; NADPH Dehydrogenase; Neurons; Neuropeptide Y; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Reference Values; Somatostatin; Substance P	1991
Neural grafts and pharmacological intervention in a model of Huntington's disease. Brain research bulletin, 1990, Volume: 25, Issue:3 Topics: Acetylcholinesterase; Amphetamine; Animals; Brain Tissue Transplantation; Catalepsy; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Electron Transport Complex IV; Female; Fetal Tissue Transplantation; Huntington Disease; Immunohistochemistry; Kainic Acid; Motor Activity; Nerve Degeneration; Pregnancy; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains	1990
T1 and T2 weighted magnetic resonance imaging of excitotoxin lesions and neural transplants in rat brain in vivo. Experimental neurology, 1990, Volume: 109, Issue:2 Topics: Animals; Corpus Striatum; Disease Models, Animal; Huntington Disease; Kainic Acid; Magnetic Resonance Imaging; Male; Rats; Rats, Inbred Strains	1990
Elevation of Met-enkephalin-like immunoreactivity in the rat striatum and globus pallidus following the focal injection of excitotoxins. Brain research, 1990, Dec-17, Volume: 536, Issue:1-2 Topics: Animals; Corpus Striatum; Enkephalin, Methionine; Globus Pallidus; Huntington Disease; Injections; Kainic Acid; Male; N-Methylaspartate; Neurotoxins; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Radioimmunoassay; Rats; Rats, Inbred Strains	1990
Intraparenchymal striatal transplants required for maintenance of behavioral recovery in an animal model of Huntington's disease. Journal of neural transplantation, 1989, Volume: 1, Issue:1 Topics: Analysis of Variance; Animals; Brain Tissue Transplantation; Corpus Striatum; Disease Models, Animal; Electroshock; Huntington Disease; Kainic Acid; Male; Motor Activity; Rats; Rats, Inbred Strains	1989
L-Homocysteic acid as an alternative cytotoxin for studying glutamate-induced cellular degeneration of Huntington's disease and normal skin fibroblasts. Life sciences, 1985, Oct-21, Volume: 37, Issue:16 Topics: Aspartic Acid; Cell Survival; Cells, Cultured; Cysteic Acid; Cysteine; Fibroblasts; Glutamates; Glutamic Acid; Homocysteine; Humans; Huntington Disease; In Vitro Techniques; Isomerism; Kainic Acid; Kinetics; N-Methylaspartate; Neurotransmitter Agents; Skin; Time Factors	1985
Excitotoxin lesions do not mimic the alteration of somatostatin in Huntington's disease. Brain research, 1985, Dec-30, Volume: 361, Issue:1-2 Topics: Animals; Brain; Corpus Striatum; Disease Models, Animal; Enkephalin, Leucine; Humans; Huntington Disease; Ibotenic Acid; Immune Sera; Immunoassay; Kainic Acid; Male; Neurons; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin; Tissue Distribution	1985
Neurons containing NADPH-diaphorase are selectively resistant to quinolinate toxicity. Science (New York, N.Y.), 1986, Oct-03, Volume: 234, Issue:4772 Topics: Animals; Aspartic Acid; Glutamates; Glutamic Acid; Humans; Huntington Disease; Kainic Acid; Mice; N-Methylaspartate; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; Neurons; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid	1986
[Activity of substantia nigra pars reticulata neurons after lesion of the ipsilateral neostriatum by kainic acid in rats]. Journal de physiologie, 1985, Volume: 80, Issue:5 Topics: Animals; Caudate Nucleus; Disease Models, Animal; Electrophysiology; Huntington Disease; Kainic Acid; Male; Neurons; Putamen; Rats; Rats, Inbred Strains; Substantia Nigra	1985
Morphologic evidence of a primary response of gila to kainic acid administration into the rat neostriatum; studied in vivo and in vitro. Experimental neurology, 1986, Volume: 92, Issue:3 Topics: Animals; Astrocytes; Corpus Striatum; Culture Media; Huntington Disease; Injections; Kainic Acid; Microscopy, Electron; Neuroglia; Organ Culture Techniques; Rats; Rats, Inbred Strains; Time Factors	1986
Neonatal striatal grafts prevent lethal syndrome produced by bilateral intrastriatal injection of kainic acid. Brain research, 1986, Jul-02, Volume: 377, Issue:1 Topics: Animals; Animals, Newborn; Basal Ganglia Diseases; Corpus Striatum; Disease Models, Animal; Female; Huntington Disease; Kainic Acid; Rats; Rats, Inbred Lew	1986
Locomotor hyperactivity: effects of multiple striatal transplants in an animal model of Huntington's disease. Pharmacology, biochemistry, and behavior, 1986, Volume: 25, Issue:1 Topics: Animals; Corpus Striatum; Disease Models, Animal; Fetus; Huntington Disease; Kainic Acid; Male; Rats	1986
Experimental striatal degeneration induced by kainic acid administration: relevance to morphological changes in Huntington's disease. The Japanese journal of psychiatry and neurology, 1986, Volume: 40, Issue:1 Topics: Animals; Corpus Striatum; Disease Models, Animal; Huntington Disease; Kainic Acid; Male; Microinjections; Microscopy, Electron; Nerve Degeneration; Rats; Rats, Inbred Strains; Stereotaxic Techniques	1986
Intraparenchymal fetal striatal transplants and recovery in kainic acid lesioned rats. Brain research, 1988, Apr-12, Volume: 446, Issue:1 Topics: Animals; Corpus Striatum; Disease Models, Animal; Fetus; Huntington Disease; Kainic Acid; Motor Activity; Rats	1988