kaempferol-3-o-rhamnoside and Pseudomonas-Infections

kaempferol-3-o-rhamnoside has been researched along with Pseudomonas-Infections* in 1 studies

Other Studies

1 other study(ies) available for kaempferol-3-o-rhamnoside and Pseudomonas-Infections

Article	Year
Antibacterial effects of afzelin isolated from Cornus macrophylla on Pseudomonas aeruginosa, a leading cause of illness in immunocompromised individuals. Molecules (Basel, Switzerland), 2014, Mar-17, Volume: 19, Issue:3 The crude ethyl acetate extract of the leaves of Cornus macrophylla showed antibacterial activity against Pseudomonas aeruginosa, a leading cause of illness in immunocompromised individuals. Bioactivity-guided separation led to the isolation of kaempferol 3-O-α-L-rhamnopyranoside (afzelin). The structure was determined based on evaluation of its spectroscopic (UV, MS, and NMR) data. The minimum inhibitory concentration (MIC) of afzelin against Pseudomonas aeruginosa was found to be 31 µg/mL. In addition, the results indicated that a hydroxyl group at C3 of the C-ring of the flavone skeleton and the rhamnose group may act as a negative factor and an enhancing factor, respectively, in the antibacterial activities of afzelin. Topics: Anti-Bacterial Agents; Cornus; Humans; Immunocompromised Host; Mannosides; Microbial Sensitivity Tests; Plant Extracts; Proanthocyanidins; Pseudomonas aeruginosa; Pseudomonas Infections	2014

Article

Year

Antibacterial effects of afzelin isolated from Cornus macrophylla on Pseudomonas aeruginosa, a leading cause of illness in immunocompromised individuals.

Molecules (Basel, Switzerland), 2014, Mar-17, Volume: 19, Issue:3

The crude ethyl acetate extract of the leaves of Cornus macrophylla showed antibacterial activity against Pseudomonas aeruginosa, a leading cause of illness in immunocompromised individuals. Bioactivity-guided separation led to the isolation of kaempferol 3-O-α-L-rhamnopyranoside (afzelin). The structure was determined based on evaluation of its spectroscopic (UV, MS, and NMR) data. The minimum inhibitory concentration (MIC) of afzelin against Pseudomonas aeruginosa was found to be 31 µg/mL. In addition, the results indicated that a hydroxyl group at C3 of the C-ring of the flavone skeleton and the rhamnose group may act as a negative factor and an enhancing factor, respectively, in the antibacterial activities of afzelin.

Topics: Anti-Bacterial Agents; Cornus; Humans; Immunocompromised Host; Mannosides; Microbial Sensitivity Tests; Plant Extracts; Proanthocyanidins; Pseudomonas aeruginosa; Pseudomonas Infections

2014