jyl-1421 and Pain
jyl-1421 has been researched along with Pain* in 1 studies
Other Studies
1 other study(ies) available for jyl-1421 and Pain
| Article | Year |
|---|---|
Novel non-vanilloid VR1 antagonist of high analgesic effects and its structural requirement for VR1 antagonistic effects.
A novel non-vanilloid VR1 antagonist consisting of a new vanilloid equivalent exhibits excellent analgesic effects as well as highly potent antagonistic activities in both capsaicin single channel and calcium uptake assays. In addition, the structural requirement for the vanilloid equivalent of the potent VR1 antagonist has also been elucidated. Topics: Analgesics; Animals; Capsaicin; Mice; Models, Molecular; Molecular Conformation; Pain; Receptors, Drug; Structure-Activity Relationship | 2003 |