juglone has been researched along with Prostatic Neoplasms in 6 studies
juglone: structure
juglone : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.
Prostatic Neoplasms: Tumors or cancer of the PROSTATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The treatments currently used for prostate cancer (PC) do not meet clinical needs, and thus, new therapies with greater effectiveness are urgently required." | 1.91 | Juglone promotes antitumor activity against prostate cancer via suppressing glycolysis and oxidative phosphorylation. ( Fang, F; Hu, C; Li, Z; Liu, D; Wang, L; Xu, H; Zhang, S, 2023) |
| "Juglone is a natural compound which has been isolated from Juglans mandshurica Maxim." | 1.39 | Juglone, isolated from Juglans mandshurica Maxim, induces apoptosis via down-regulation of AR expression in human prostate cancer LNCaP cells. ( Qu, S; Sui, D; Xu, H; Yu, X, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, H | 2 |
| Yu, X | 1 |
| Qu, S | 1 |
| Sui, D | 1 |
| Li, K | 2 |
| Ma, T | 1 |
| Cai, J | 1 |
| Huang, M | 2 |
| Guo, H | 1 |
| Zhou, D | 1 |
| Luan, S | 1 |
| Yang, J | 1 |
| Liu, D | 3 |
| Jing, Y | 2 |
| Zhao, L | 2 |
| Li, A | 1 |
| Zhao, F | 1 |
| Xie, X | 1 |
| Hu, C | 1 |
| Li, Z | 1 |
| Zhang, S | 1 |
| Fang, F | 1 |
| Wang, L | 1 |
| de Freitas, PP | 1 |
| Ribeiro, RCB | 1 |
| Dos Santos Guimarães, I | 1 |
| Moreira, CS | 1 |
| Rocha, DR | 1 |
| de Carvalho da Silva, F | 1 |
| Ferreira, VF | 1 |
| Gimba, ERP | 1 |
| Kanaoka, R | 1 |
| Kushiyama, A | 1 |
| Seno, Y | 1 |
| Nakatsu, Y | 1 |
| Matsunaga, Y | 1 |
| Fukushima, T | 1 |
| Tsuchiya, Y | 1 |
| Sakoda, H | 1 |
| Fujishiro, M | 1 |
| Yamamotoya, T | 1 |
| Kamata, H | 1 |
| Matsubara, A | 1 |
| Asano, T | 1 |
6 other studies available for juglone and Prostatic Neoplasms
| Article | Year |
|---|---|
Juglone, isolated from Juglans mandshurica Maxim, induces apoptosis via down-regulation of AR expression in human prostate cancer LNCaP cells.
Topics: Apoptosis; Cell Line, Tumor; Down-Regulation; Humans; Juglans; Male; Plant Extracts; Prostatic Neopl | 2013 |
Conjugates of 18β-glycyrrhetinic acid derivatives with 3-(1H-benzo[d]imidazol-2-yl)propanoic acid as Pin1 inhibitors displaying anti-prostate cancer ability.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug | 2017 |
Design, synthesis and biological evaluation of ring A modified 11-keto-boswellic acid derivatives as Pin1 inhibitors with remarkable anti-prostate cancer activity.
Topics: Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Drug Design; Humans; Male; Molecular D | 2018 |
Juglone promotes antitumor activity against prostate cancer via suppressing glycolysis and oxidative phosphorylation.
Topics: Cell Line, Tumor; Energy Metabolism; Glycolysis; Hexokinase; Humans; Male; Oxidative Phosphorylation | 2023 |
(3,3'-Methylene)bis-2-hydroxy-1,4-naphthoquinones induce cytotoxicity against DU145 and PC3 cancer cells by inhibiting cell viability and promoting cell cycle arrest.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Prolife | 2021 |
Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines.
Topics: Animals; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Nude; N | 2015 |