juglone has been researched along with Parkinson Disease in 2 studies
juglone: structure
juglone : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thabit, S | 1 |
| Handoussa, H | 1 |
| ElSayed, NS | 1 |
| Breitinger, HG | 1 |
| Breitinger, U | 1 |
| Wink, M | 1 |
| Ghosh, A | 1 |
| Saminathan, H | 1 |
| Kanthasamy, A | 1 |
| Anantharam, V | 1 |
| Jin, H | 1 |
| Sondarva, G | 1 |
| Harischandra, DS | 1 |
| Qian, Z | 1 |
| Rana, A | 1 |
| Kanthasamy, AG | 1 |
2 other studies available for juglone and Parkinson Disease
| Article | Year |
|---|---|
A fruit extract of Styphnolobium japonicum (L.) counteracts oxidative stress and mediates neuroprotection in Caenorhabditis elegans.
Topics: alpha-Synuclein; Amyloid beta-Peptides; Animals; Caenorhabditis elegans; Fruit; Neuroprotection; Oxi | 2023 |
The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Brain | 2013 |