juglone has been researched along with Neoplasms in 9 studies
juglone: structure
juglone : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This review focuses on the anti-cancer prospects of plant-derived quinones, namely, aloe-emodin, juglone, β-lapachol, plumbagin, shikonin, and thymoquinone." | 2.49 | Quinones derived from plant secondary metabolites as anti-cancer agents. ( Bao, JL; Chen, XP; Huang, MQ; Lu, JJ; Wang, YT; Wu, GS; Xu, WS, 2013) |
| "Furthermore, we verified that metastasis was suppressed by juglone treatment." | 1.91 | Juglone Inhibits Tumor Metastasis by Regulating Stemness Characteristics and the Epithelial-to-Mesenchymal Transition in Cancer Cells both ( Chen, X; Ding, S; Gao, X; Jin, J; Le, Y; Matunda, C; Wang, H; Wang, L; Yu, Y; Zou, C, 2023) |
| "Juglone has been showed to exert a direct cytotoxic effect on tumor cells." | 1.51 | Juglone eliminates MDSCs accumulation and enhances antitumor immunity. ( Cui, Y; E, F; Gao, X; Qiu, Z; Wang, H; Yu, Y; Zhang, H; Zhao, W; Zou, C, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 3 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 2 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 2 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Furqan, M | 1 |
| Fayyaz, A | 1 |
| Firdous, F | 1 |
| Raza, H | 1 |
| Bilal, A | 1 |
| Saleem, RSZ | 1 |
| Shahzad-Ul-Hussan, S | 1 |
| Youssef, FS | 1 |
| Al Musayeib, NM | 1 |
| Ashour, ML | 1 |
| Hussain, H | 1 |
| Faisal, A | 1 |
| Tang, YT | 1 |
| Chu, P | 1 |
| Ma, XD | 1 |
| Tang, ZY | 1 |
| Sun, ZL | 1 |
| Zou, C | 4 |
| Yu, Y | 2 |
| Wang, H | 2 |
| Matunda, C | 1 |
| Ding, S | 1 |
| Wang, L | 1 |
| Chen, X | 1 |
| Le, Y | 1 |
| Jin, J | 1 |
| Gao, X | 2 |
| Zhao, W | 1 |
| Cui, Y | 1 |
| Zhang, H | 1 |
| E, F | 1 |
| Qiu, Z | 1 |
| Chen, XG | 1 |
| Zhang, Y | 1 |
| Lu, JJ | 1 |
| Bao, JL | 1 |
| Wu, GS | 1 |
| Xu, WS | 1 |
| Huang, MQ | 1 |
| Chen, XP | 1 |
| Wang, YT | 1 |
| Morrissey, JM | 1 |
| Taylor, KD | 1 |
| Gilman, SD | 1 |
| Cenas, N | 1 |
| Prast, S | 1 |
| Nivinskas, H | 1 |
| Sarlauskas, J | 1 |
| Arnér, ES | 1 |
5 reviews available for juglone and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
Identification and Characterization of Natural and Semisynthetic Quinones as Aurora Kinase Inhibitors.
Topics: Anthraquinones; Aurora Kinase A; Aurora Kinase B; Cell Line, Tumor; DNA Helicases; Humans; Neoplasms | 2022 |
Molecular biological mechanism of action in cancer therapies: Juglone and its derivatives, the future of development.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Cell Movement; Cell Proliferation; DNA-Directed DNA Pol | 2022 |
[Recent advance in the study of novel anti-tumor targets and drugs--aurora kinase and Pin1].
Topics: Antineoplastic Agents; Apoptosis; Aurora Kinases; Humans; Naphthoquinones; Neoplasms; NIMA-Interacti | 2009 |
Quinones derived from plant secondary metabolites as anti-cancer agents.
Topics: Anthraquinones; Antineoplastic Agents, Phytogenic; Benzoquinones; Cell Line, Tumor; Cell Survival; H | 2013 |
4 other studies available for juglone and Neoplasms
| Article | Year |
|---|---|
Juglone Inhibits Tumor Metastasis by Regulating Stemness Characteristics and the Epithelial-to-Mesenchymal Transition in Cancer Cells both
Topics: Apoptosis; Blotting, Western; Epithelial-Mesenchymal Transition; Naphthoquinones; Neoplasm Metastasi | 2023 |
Juglone eliminates MDSCs accumulation and enhances antitumor immunity.
Topics: Animals; Antineoplastic Agents; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Chemical and Drug Indu | 2019 |
Ultrasound-mediated release of iron from ferritin.
Topics: Antineoplastic Agents; Combined Modality Therapy; Ferritins; Iron; Naphthoquinones; Neoplasms; Oxida | 2003 |
Interactions of nitroaromatic compounds with the mammalian selenoprotein thioredoxin reductase and the relation to induction of apoptosis in human cancer cells.
Topics: Animals; Apoptosis; Binding Sites; Caspase 3; Caspase 7; Caspases; Cell Line, Tumor; Dinitrobenzenes | 2006 |