juglone has been researched along with Melanoma in 4 studies
juglone: structure
juglone : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study demonstrates cytotoxic and genotoxic potential of juglone, a chief constituent of walnut, and its underlying mechanisms against melanoma cells." | 7.75 | Juglone, a naphthoquinone from walnut, exerts cytotoxic and genotoxic effects against cultured melanoma tumor cells. ( Aithal, BK; Kumar, MR; Rao, BN; Rao, BS; Udupa, N, 2009) |
| "Juglone is a natural compound isolated from walnut trees." | 5.46 | Juglone potentiates TRAIL‑induced apoptosis in human melanoma cells via activating the ROS‑p38‑p53 pathway. ( Chen, Y; Ding, F; Du, J; Li, J; Liu, X; Liu, Y; Lv, Y; Mo, S; Wu, J; Zhang, Y, 2017) |
| "This study demonstrates cytotoxic and genotoxic potential of juglone, a chief constituent of walnut, and its underlying mechanisms against melanoma cells." | 3.75 | Juglone, a naphthoquinone from walnut, exerts cytotoxic and genotoxic effects against cultured melanoma tumor cells. ( Aithal, BK; Kumar, MR; Rao, BN; Rao, BS; Udupa, N, 2009) |
| "Juglone is a natural compound isolated from walnut trees." | 1.46 | Juglone potentiates TRAIL‑induced apoptosis in human melanoma cells via activating the ROS‑p38‑p53 pathway. ( Chen, Y; Ding, F; Du, J; Li, J; Liu, X; Liu, Y; Lv, Y; Mo, S; Wu, J; Zhang, Y, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yue, WH | 1 |
| Qin, LQ | 1 |
| Cai, J | 1 |
| Mei, R | 1 |
| Qian, HQ | 1 |
| Zou, ZY | 1 |
| Li, Z | 1 |
| Liu, X | 2 |
| Li, M | 1 |
| Chai, J | 1 |
| He, S | 1 |
| Wu, J | 2 |
| Xu, J | 1 |
| Chen, Y | 1 |
| Zhang, Y | 1 |
| Du, J | 1 |
| Lv, Y | 1 |
| Mo, S | 1 |
| Liu, Y | 1 |
| Ding, F | 1 |
| Li, J | 1 |
| Aithal, BK | 1 |
| Kumar, MR | 1 |
| Rao, BN | 1 |
| Udupa, N | 1 |
| Rao, BS | 1 |
4 other studies available for juglone and Melanoma
| Article | Year |
|---|---|
Jug-PLGA-NPs, a New Form of Juglone with Enhanced Efficiency and Reduced Toxicity on Melanoma.
Topics: Animals; Cell Line, Tumor; Delayed-Action Preparations; Drug Carriers; Melanoma; Mice; Mice, Nude; N | 2022 |
Juglone potentiates BRAF inhibitor‑induced apoptosis in melanoma through reactive oxygen species and the p38‑p53 pathway.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Humans; MAP Kinase Signaling System; Melanoma; N | 2020 |
Juglone potentiates TRAIL‑induced apoptosis in human melanoma cells via activating the ROS‑p38‑p53 pathway.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Humans; Melanoma; Naphthoquinones; p38 Mitogen-Activated | 2017 |
Juglone, a naphthoquinone from walnut, exerts cytotoxic and genotoxic effects against cultured melanoma tumor cells.
Topics: Animals; Annexin A5; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; DNA Fragment | 2009 |