juglone has been researched along with Malignant Melanoma in 4 studies
juglone: structure
juglone : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study demonstrates cytotoxic and genotoxic potential of juglone, a chief constituent of walnut, and its underlying mechanisms against melanoma cells." | 7.75 | Juglone, a naphthoquinone from walnut, exerts cytotoxic and genotoxic effects against cultured melanoma tumor cells. ( Aithal, BK; Kumar, MR; Rao, BN; Rao, BS; Udupa, N, 2009) |
| "Juglone is a natural compound isolated from walnut trees." | 5.46 | Juglone potentiates TRAIL‑induced apoptosis in human melanoma cells via activating the ROS‑p38‑p53 pathway. ( Chen, Y; Ding, F; Du, J; Li, J; Liu, X; Liu, Y; Lv, Y; Mo, S; Wu, J; Zhang, Y, 2017) |
| "This study demonstrates cytotoxic and genotoxic potential of juglone, a chief constituent of walnut, and its underlying mechanisms against melanoma cells." | 3.75 | Juglone, a naphthoquinone from walnut, exerts cytotoxic and genotoxic effects against cultured melanoma tumor cells. ( Aithal, BK; Kumar, MR; Rao, BN; Rao, BS; Udupa, N, 2009) |
| "Juglone is a natural compound isolated from walnut trees." | 1.46 | Juglone potentiates TRAIL‑induced apoptosis in human melanoma cells via activating the ROS‑p38‑p53 pathway. ( Chen, Y; Ding, F; Du, J; Li, J; Liu, X; Liu, Y; Lv, Y; Mo, S; Wu, J; Zhang, Y, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yue, WH | 1 |
| Qin, LQ | 1 |
| Cai, J | 1 |
| Mei, R | 1 |
| Qian, HQ | 1 |
| Zou, ZY | 1 |
| Li, Z | 1 |
| Liu, X | 2 |
| Li, M | 1 |
| Chai, J | 1 |
| He, S | 1 |
| Wu, J | 2 |
| Xu, J | 1 |
| Chen, Y | 1 |
| Zhang, Y | 1 |
| Du, J | 1 |
| Lv, Y | 1 |
| Mo, S | 1 |
| Liu, Y | 1 |
| Ding, F | 1 |
| Li, J | 1 |
| Aithal, BK | 1 |
| Kumar, MR | 1 |
| Rao, BN | 1 |
| Udupa, N | 1 |
| Rao, BS | 1 |
4 other studies available for juglone and Malignant Melanoma
| Article | Year |
|---|---|
Jug-PLGA-NPs, a New Form of Juglone with Enhanced Efficiency and Reduced Toxicity on Melanoma.
Topics: Animals; Cell Line, Tumor; Delayed-Action Preparations; Drug Carriers; Melanoma; Mice; Mice, Nude; N | 2022 |
Juglone potentiates BRAF inhibitor‑induced apoptosis in melanoma through reactive oxygen species and the p38‑p53 pathway.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Humans; MAP Kinase Signaling System; Melanoma; N | 2020 |
Juglone potentiates TRAIL‑induced apoptosis in human melanoma cells via activating the ROS‑p38‑p53 pathway.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Humans; Melanoma; Naphthoquinones; p38 Mitogen-Activated | 2017 |
Juglone, a naphthoquinone from walnut, exerts cytotoxic and genotoxic effects against cultured melanoma tumor cells.
Topics: Animals; Annexin A5; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; DNA Fragment | 2009 |