Page last updated: 2024-10-29

juglone and Inflammation

juglone has been researched along with Inflammation in 7 studies

juglone: structure
juglone : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"The current study was performed to evaluate the therapeutic impacts of the juglone in acetic acid-induced colitis in male Wistar rats."8.31Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023)
" This study implies the therapeutic effect of IND and juglone [JUG] against colon carcinogenesis, without gastric ulceration - an adverse side effect of IND."8.02Effects of combined treatment with Indomethacin and Juglone on AOM/DSS induced colon carcinogenesis in Balb/c mice: Roles of inflammation and apoptosis. ( Devaraj, H; Seetha, A; Sudhandiran, G, 2021)
"The current study was performed to evaluate the therapeutic impacts of the juglone in acetic acid-induced colitis in male Wistar rats."4.31Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats. ( Abdolghaffari, AH; Abdollahi, AR; Alizadeh Nobakht, NA; Esmaealzadeh, N; Khayatan, D; Lashgari, NA; Momeni Roudsari, N; Momtaz, S; Niknejad, A; Tavakoli, S, 2023)
" This study implies the therapeutic effect of IND and juglone [JUG] against colon carcinogenesis, without gastric ulceration - an adverse side effect of IND."4.02Effects of combined treatment with Indomethacin and Juglone on AOM/DSS induced colon carcinogenesis in Balb/c mice: Roles of inflammation and apoptosis. ( Devaraj, H; Seetha, A; Sudhandiran, G, 2021)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (28.57)24.3611
2020's5 (71.43)2.80

Authors

AuthorsStudies
Maruo, S1
Kuriyama, I1
Kuramochi, K1
Tsubaki, K1
Yoshida, H1
Mizushina, Y1
Şenol, N1
Şahin, M1
Şahin, U1
Alizadeh Nobakht, NA1
Lashgari, NA1
Momeni Roudsari, N1
Niknejad, A1
Khayatan, D1
Tavakoli, S1
Abdollahi, AR1
Esmaealzadeh, N1
Momtaz, S1
Abdolghaffari, AH1
Kim, NH1
Kim, HK1
Lee, JH1
Jo, SI1
Won, HM1
Lee, GS1
Lee, HS1
Nam, KW1
Kim, WJ1
Han, MD1
Seetha, A1
Devaraj, H1
Sudhandiran, G1
Chen, S1
Wu, X1
Yu, Z1
Peng, X1
Nie, Y1
Wu, J1
Huang, Q1
Cheng, Y1

Other Studies

7 other studies available for juglone and Inflammation

ArticleYear
Inhibitory effect of novel 5-O-acyl juglones on mammalian DNA polymerase activity, cancer cell growth and inflammatory response.
    Bioorganic & medicinal chemistry, 2011, Oct-01, Volume: 19, Issue:19

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line, Tumor; DNA Polymerase beta; Enz

2011
Protective effect of juglone on electric field-induced apoptosis and inflammation in liver and kidney tissue in rats.
    Research in veterinary science, 2023, Volume: 164

    Topics: Animals; Apoptosis; Caspase 3; Inflammation; Kidney; Liver; Male; Oxidative Stress; Rats; Rats, Wist

2023
Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats.
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2023, Volume: 22, Issue:2

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis; Colon; Inflammation; Inflamma

2023
Juglone Suppresses LPS-induced Inflammatory Responses and NLRP3 Activation in Macrophages.
    Molecules (Basel, Switzerland), 2020, Jul-07, Volume: 25, Issue:13

    Topics: Animals; Cell Line; Inflammation; Interleukin-18; Interleukin-1beta; Lipopolysaccharides; Macrophage

2020
Effects of combined treatment with Indomethacin and Juglone on AOM/DSS induced colon carcinogenesis in Balb/c mice: Roles of inflammation and apoptosis.
    Life sciences, 2021, Jan-01, Volume: 264

    Topics: Animals; Apoptosis; Azoxymethane; Carcinogenesis; Cell Count; Cell Line, Tumor; Collagen; Colonic Ne

2021
Juglone Suppresses Inflammation and Oxidative Stress in Colitis Mice.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Animals; Colitis, Ulcerative; Inflammation; Male; Mice; Mice, Inbred C57BL; Naphthoquinones; Oxidati

2021
Juglone prevents metabolic endotoxemia-induced hepatitis and neuroinflammation via suppressing TLR4/NF-κB signaling pathway in high-fat diet rats.
    Biochemical and biophysical research communications, 2015, Jul-03, Volume: 462, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Astrocytes; Cytokines; Diet, High-Fat; Endotoxemia; Hepatitis, An

2015