Page last updated: 2024-10-29

juglone and Glioma

juglone has been researched along with Glioma in 2 studies

juglone: structure
juglone : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"Malignant gliomas are aggressive and life-threatening tumours that still show a poor prognosis: the current therapeutic approach based on surgical resection and chemotherapy combined with radiotherapy does not provide a satisfactory chance of long-term survival to patients."5.46Antiproliferative activity of Juglone derivatives on rat glioma. ( Mucignat-Caretta, C; Pavan, V; Pezzani, R; Redaelli, M; Ribaudo, G; Zagotto, G; Zorzan, M, 2017)
" We have already shown that 5-hydroxy-1,4-naphthalenedione (juglone) exerts antiproliferative, anti-invasive, and cytotoxic effects on glioma C6 cells."3.855-Hydroxy-1,4-naphthalenedione exerts anticancer effects on glioma cells through interaction with the mitochondrial electron transport chain. ( Li, N; Liobikas, J; Sidlauskas, K; Sidlauskiene, R, 2017)
"Malignant gliomas are aggressive and life-threatening tumours that still show a poor prognosis: the current therapeutic approach based on surgical resection and chemotherapy combined with radiotherapy does not provide a satisfactory chance of long-term survival to patients."1.46Antiproliferative activity of Juglone derivatives on rat glioma. ( Mucignat-Caretta, C; Pavan, V; Pezzani, R; Redaelli, M; Ribaudo, G; Zagotto, G; Zorzan, M, 2017)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pavan, V1
Ribaudo, G1
Zorzan, M1
Redaelli, M1
Pezzani, R1
Mucignat-Caretta, C1
Zagotto, G1
Sidlauskas, K1
Sidlauskiene, R1
Li, N1
Liobikas, J1

Other Studies

2 other studies available for juglone and Glioma

ArticleYear
Antiproliferative activity of Juglone derivatives on rat glioma.
    Natural product research, 2017, Volume: 31, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proli

2017
5-Hydroxy-1,4-naphthalenedione exerts anticancer effects on glioma cells through interaction with the mitochondrial electron transport chain.
    Neuroscience letters, 2017, 02-03, Volume: 639

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Electron Transport; Glioma; Humans; Mitochondria;

2017