juglone and Glioma
juglone has been researched along with Glioma in 2 studies
juglone: structure
juglone : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Malignant gliomas are aggressive and life-threatening tumours that still show a poor prognosis: the current therapeutic approach based on surgical resection and chemotherapy combined with radiotherapy does not provide a satisfactory chance of long-term survival to patients." | 5.46 | Antiproliferative activity of Juglone derivatives on rat glioma. ( Mucignat-Caretta, C; Pavan, V; Pezzani, R; Redaelli, M; Ribaudo, G; Zagotto, G; Zorzan, M, 2017) |
| " We have already shown that 5-hydroxy-1,4-naphthalenedione (juglone) exerts antiproliferative, anti-invasive, and cytotoxic effects on glioma C6 cells." | 3.85 | 5-Hydroxy-1,4-naphthalenedione exerts anticancer effects on glioma cells through interaction with the mitochondrial electron transport chain. ( Li, N; Liobikas, J; Sidlauskas, K; Sidlauskiene, R, 2017) |
| "Malignant gliomas are aggressive and life-threatening tumours that still show a poor prognosis: the current therapeutic approach based on surgical resection and chemotherapy combined with radiotherapy does not provide a satisfactory chance of long-term survival to patients." | 1.46 | Antiproliferative activity of Juglone derivatives on rat glioma. ( Mucignat-Caretta, C; Pavan, V; Pezzani, R; Redaelli, M; Ribaudo, G; Zagotto, G; Zorzan, M, 2017) |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Pavan, V | 1 |
| Ribaudo, G | 1 |
| Zorzan, M | 1 |
| Redaelli, M | 1 |
| Pezzani, R | 1 |
| Mucignat-Caretta, C | 1 |
| Zagotto, G | 1 |
| Sidlauskas, K | 1 |
| Sidlauskiene, R | 1 |
| Li, N | 1 |
| Liobikas, J | 1 |
Other Studies
2 other studies available for juglone and Glioma
| Article | Year |
|---|---|
Antiproliferative activity of Juglone derivatives on rat glioma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proli | 2017 |
5-Hydroxy-1,4-naphthalenedione exerts anticancer effects on glioma cells through interaction with the mitochondrial electron transport chain.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Electron Transport; Glioma; Humans; Mitochondria; | 2017 |