Page last updated: 2024-10-29

juglone and Glial Cell Tumors

juglone has been researched along with Glial Cell Tumors in 2 studies

juglone: structure
juglone : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.

Research Excerpts

ExcerptRelevanceReference
"Malignant gliomas are aggressive and life-threatening tumours that still show a poor prognosis: the current therapeutic approach based on surgical resection and chemotherapy combined with radiotherapy does not provide a satisfactory chance of long-term survival to patients."5.46Antiproliferative activity of Juglone derivatives on rat glioma. ( Mucignat-Caretta, C; Pavan, V; Pezzani, R; Redaelli, M; Ribaudo, G; Zagotto, G; Zorzan, M, 2017)
" We have already shown that 5-hydroxy-1,4-naphthalenedione (juglone) exerts antiproliferative, anti-invasive, and cytotoxic effects on glioma C6 cells."3.855-Hydroxy-1,4-naphthalenedione exerts anticancer effects on glioma cells through interaction with the mitochondrial electron transport chain. ( Li, N; Liobikas, J; Sidlauskas, K; Sidlauskiene, R, 2017)
"Malignant gliomas are aggressive and life-threatening tumours that still show a poor prognosis: the current therapeutic approach based on surgical resection and chemotherapy combined with radiotherapy does not provide a satisfactory chance of long-term survival to patients."1.46Antiproliferative activity of Juglone derivatives on rat glioma. ( Mucignat-Caretta, C; Pavan, V; Pezzani, R; Redaelli, M; Ribaudo, G; Zagotto, G; Zorzan, M, 2017)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pavan, V1
Ribaudo, G1
Zorzan, M1
Redaelli, M1
Pezzani, R1
Mucignat-Caretta, C1
Zagotto, G1
Sidlauskas, K1
Sidlauskiene, R1
Li, N1
Liobikas, J1

Other Studies

2 other studies available for juglone and Glial Cell Tumors

ArticleYear
Antiproliferative activity of Juglone derivatives on rat glioma.
    Natural product research, 2017, Volume: 31, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proli

2017
5-Hydroxy-1,4-naphthalenedione exerts anticancer effects on glioma cells through interaction with the mitochondrial electron transport chain.
    Neuroscience letters, 2017, 02-03, Volume: 639

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Electron Transport; Glioma; Humans; Mitochondria;

2017