Page last updated: 2024-10-29

juglone and Colonic Neoplasms

juglone has been researched along with Colonic Neoplasms in 6 studies

juglone: structure
juglone : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.

Colonic Neoplasms: Tumors or cancer of the COLON.

Research Excerpts

ExcerptRelevanceReference
" This study implies the therapeutic effect of IND and juglone [JUG] against colon carcinogenesis, without gastric ulceration - an adverse side effect of IND."8.02Effects of combined treatment with Indomethacin and Juglone on AOM/DSS induced colon carcinogenesis in Balb/c mice: Roles of inflammation and apoptosis. ( Devaraj, H; Seetha, A; Sudhandiran, G, 2021)
" This study implies the therapeutic effect of IND and juglone [JUG] against colon carcinogenesis, without gastric ulceration - an adverse side effect of IND."4.02Effects of combined treatment with Indomethacin and Juglone on AOM/DSS induced colon carcinogenesis in Balb/c mice: Roles of inflammation and apoptosis. ( Devaraj, H; Seetha, A; Sudhandiran, G, 2021)
"Treatment with juglone was not as effective as with indomethacin; however, a combination of both was shown to be more effective, suggesting that juglone may be considered for therapeutic intervention of colon cancer."1.56Indomethacin and juglone inhibit inflammatory molecules to induce apoptosis in colon cancer cells. ( Devaraj, H; Seetha, A; Sudhandiran, G, 2020)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's3 (50.00)2.80

Authors

AuthorsStudies
Seetha, A2
Devaraj, H2
Sudhandiran, G2
González-Montiel, GA1
Kaweesa, EN1
Feau, N1
Hamelin, RC1
Stone, JK1
Loesgen, S1
Spoerlein-Guettler, C1
Mahal, K1
Schobert, R1
Biersack, B1
Sugie, S1
Okamoto, K1
Rahman, KM1
Tanaka, T1
Kawai, K1
Yamahara, J1
Mori, H1
Kamei, H1
Koide, T1
Kojima, T1
Hashimoto, Y1
Hasegawa, M1

Other Studies

6 other studies available for juglone and Colonic Neoplasms

ArticleYear
Indomethacin and juglone inhibit inflammatory molecules to induce apoptosis in colon cancer cells.
    Journal of biochemical and molecular toxicology, 2020, Volume: 34, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Prot

2020
Chemical, Bioactivity, and Biosynthetic Screening of Epiphytic Fungus
    Molecules (Basel, Switzerland), 2020, May-19, Volume: 25, Issue:10

    Topics: Anti-Bacterial Agents; Ascomycota; Biosynthetic Pathways; Cell Proliferation; Colonic Neoplasms; Gen

2020
Effects of combined treatment with Indomethacin and Juglone on AOM/DSS induced colon carcinogenesis in Balb/c mice: Roles of inflammation and apoptosis.
    Life sciences, 2021, Jan-01, Volume: 264

    Topics: Animals; Apoptosis; Azoxymethane; Carcinogenesis; Cell Count; Cell Line, Tumor; Collagen; Colonic Ne

2021
Ferrocene and (arene)ruthenium(II) complexes of the natural anticancer naphthoquinone plumbagin with enhanced efficacy against resistant cancer cells and a genuine mode of action.
    Journal of inorganic biochemistry, 2014, Volume: 138

    Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Cell Cycle; Cell L

2014
Inhibitory effects of plumbagin and juglone on azoxymethane-induced intestinal carcinogenesis in rats.
    Cancer letters, 1998, May-15, Volume: 127, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Azo Compounds; Benzopyrans; Colonic Neoplasms; Coumarins

1998
Inhibition of cell growth in culture by quinones.
    Cancer biotherapy & radiopharmaceuticals, 1998, Volume: 13, Issue:3

    Topics: Anthraquinones; Antineoplastic Agents; Arbutin; Cell Division; Colonic Neoplasms; Humans; Naphthoqui

1998