Page last updated: 2024-10-29

juglone and Breast Neoplasms

juglone has been researched along with Breast Neoplasms in 7 studies

juglone: structure
juglone : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.

Breast Neoplasms: Tumors or cancer of the human BREAST.

Research Excerpts

ExcerptRelevanceReference
"Investigating the effects of juglone loaded P188/phospholipid mixed micelles (J-MM) in breast cancer."7.83Juglone loaded poloxamer 188/phospholipid mixed micelles evaluated in vitro and in vivo in breast cancer. ( Che, D; Jin, X; Lv, H; Zhang, Y; Zhang, Z, 2016)
"This study aimed to evaluate the effects of Pin1 inhibitor Juglone on proliferation, migration and the angiogenic ability of breast cancer cell line MCF7Adr."7.81Effect of Pin1 inhibitor juglone on proliferation, migration and angiogenic ability of breast cancer cell line MCF7Adr. ( Hu, YG; Li, Y; Shen, YF, 2015)
"In human tamoxifen-resistant breast cancer, our results show a significant correlation between Pin1 overexpression and high levels of LC-3."5.36The prolyl isomerase Pin1 induces LC-3 expression and mediates tamoxifen resistance in breast cancer. ( Cho, HG; Choi, HS; Kang, BS; Khanal, P; Lim, SC; Namgoong, GM; Oh, YK; Shim, JH; Yoo, JC, 2010)
"This study investigated the nature and mechanism of juglone-induced apoptosis in the human breast cancer cell line MCF-7."3.83Mechanism of juglone-induced apoptosis of MCF-7 cells by the mitochondrial pathway. ( Ji, YB; Qu, ZY; Xin, GS; Yu, M; Zou, X, 2016)
"Investigating the effects of juglone loaded P188/phospholipid mixed micelles (J-MM) in breast cancer."3.83Juglone loaded poloxamer 188/phospholipid mixed micelles evaluated in vitro and in vivo in breast cancer. ( Che, D; Jin, X; Lv, H; Zhang, Y; Zhang, Z, 2016)
"This study aimed to evaluate the effects of Pin1 inhibitor Juglone on proliferation, migration and the angiogenic ability of breast cancer cell line MCF7Adr."3.81Effect of Pin1 inhibitor juglone on proliferation, migration and angiogenic ability of breast cancer cell line MCF7Adr. ( Hu, YG; Li, Y; Shen, YF, 2015)
"In human tamoxifen-resistant breast cancer, our results show a significant correlation between Pin1 overexpression and high levels of LC-3."1.36The prolyl isomerase Pin1 induces LC-3 expression and mediates tamoxifen resistance in breast cancer. ( Cho, HG; Choi, HS; Kang, BS; Khanal, P; Lim, SC; Namgoong, GM; Oh, YK; Shim, JH; Yoo, JC, 2010)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hu, YG1
Shen, YF1
Li, Y1
Ji, YB1
Xin, GS1
Qu, ZY1
Zou, X1
Yu, M1
Jin, X1
Zhang, Y1
Zhang, Z1
Che, D1
Lv, H1
Sajadimajd, S1
Yazdanparast, R1
Namgoong, GM1
Khanal, P1
Cho, HG1
Lim, SC1
Oh, YK1
Kang, BS1
Shim, JH2
Yoo, JC1
Choi, HS1
K A, T1
T, R1
G, R1
K C, S1
Nair, RS1
G, S1
Banerji, A1
Somasundaram, V1
Srinivas, P1
Nishi, M1
Sakai, Y1
Akutsu, H1
Nagashima, Y1
Quinn, G1
Masui, S1
Kimura, H1
Perrem, K1
Umezawa, A1
Yamamoto, N1
Lee, SW1
Ryo, A1

Other Studies

7 other studies available for juglone and Breast Neoplasms

ArticleYear
Effect of Pin1 inhibitor juglone on proliferation, migration and angiogenic ability of breast cancer cell line MCF7Adr.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2015, Volume: 35, Issue:4

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Movement; Cell Proliferation; Cyclin E; Fe

2015
Mechanism of juglone-induced apoptosis of MCF-7 cells by the mitochondrial pathway.
    Genetics and molecular research : GMR, 2016, Jul-25, Volume: 15, Issue:3

    Topics: Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Caspase 3; Cell Line, Tumor; Cytochromes c;

2016
Juglone loaded poloxamer 188/phospholipid mixed micelles evaluated in vitro and in vivo in breast cancer.
    International journal of pharmaceutics, 2016, Dec-30, Volume: 515, Issue:1-2

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Drug Carriers; Female; Humans;

2016
Sensitizing effect of juglone is mediated by down regulation of Notch1 signaling pathway in trastuzumab-resistant SKBR3 cells.
    Apoptosis : an international journal on programmed cell death, 2017, Volume: 22, Issue:1

    Topics: Breast Neoplasms; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans;

2017
The prolyl isomerase Pin1 induces LC-3 expression and mediates tamoxifen resistance in breast cancer.
    The Journal of biological chemistry, 2010, Jul-30, Volume: 285, Issue:31

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzym

2010
Structure activity relationship of plumbagin in BRCA1 related cancer cells.
    Molecular carcinogenesis, 2013, Volume: 52, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; BRCA1 Protein; Breast Neoplasms; Cell Cycle Checkpoints; Drug Scr

2013
Induction of cells with cancer stem cell properties from nontumorigenic human mammary epithelial cells by defined reprogramming factors.
    Oncogene, 2014, Jan-30, Volume: 33, Issue:5

    Topics: Animals; Breast Neoplasms; CD24 Antigen; Cell Differentiation; Cell Line, Tumor; Cell Proliferation;

2014