juglone has been researched along with Brain Neoplasms in 4 studies
juglone: structure
juglone : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this paper, we present the effects of juglone alone and in combination with temozolomide on glioblastoma cells." | 5.91 | Juglone in Combination with Temozolomide Shows a Promising Epigenetic Therapeutic Effect on the Glioblastoma Cell Line. ( Barciszewska, AM; Belter, A; Gawrońska, I; Giel-Pietraszuk, M; Naskręt-Barciszewska, MZ, 2023) |
| "Juglone could inhibit the growth of TSCs in gliomas through the activation of ROS-p38-MAPK pathway in vitro, and the anti-glioma effect was validated in vivo, which offers a potential therapeutic agent to gliomas." | 5.46 | Juglone induces apoptosis of tumor stem-like cells through ROS-p38 pathway in glioblastoma. ( Chen, L; Hua, W; Mao, Y; Wu, J; Xu, Y; Zhang, H; Zhang, J; Zhang, Y; Zhu, W, 2017) |
| "Malignant gliomas are aggressive and life-threatening tumours that still show a poor prognosis: the current therapeutic approach based on surgical resection and chemotherapy combined with radiotherapy does not provide a satisfactory chance of long-term survival to patients." | 5.46 | Antiproliferative activity of Juglone derivatives on rat glioma. ( Mucignat-Caretta, C; Pavan, V; Pezzani, R; Redaelli, M; Ribaudo, G; Zagotto, G; Zorzan, M, 2017) |
| " In this paper, we present the effects of juglone alone and in combination with temozolomide on glioblastoma cells." | 1.91 | Juglone in Combination with Temozolomide Shows a Promising Epigenetic Therapeutic Effect on the Glioblastoma Cell Line. ( Barciszewska, AM; Belter, A; Gawrońska, I; Giel-Pietraszuk, M; Naskręt-Barciszewska, MZ, 2023) |
| "Juglone could inhibit the growth of TSCs in gliomas through the activation of ROS-p38-MAPK pathway in vitro, and the anti-glioma effect was validated in vivo, which offers a potential therapeutic agent to gliomas." | 1.46 | Juglone induces apoptosis of tumor stem-like cells through ROS-p38 pathway in glioblastoma. ( Chen, L; Hua, W; Mao, Y; Wu, J; Xu, Y; Zhang, H; Zhang, J; Zhang, Y; Zhu, W, 2017) |
| "Malignant gliomas are aggressive and life-threatening tumours that still show a poor prognosis: the current therapeutic approach based on surgical resection and chemotherapy combined with radiotherapy does not provide a satisfactory chance of long-term survival to patients." | 1.46 | Antiproliferative activity of Juglone derivatives on rat glioma. ( Mucignat-Caretta, C; Pavan, V; Pezzani, R; Redaelli, M; Ribaudo, G; Zagotto, G; Zorzan, M, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barciszewska, AM | 1 |
| Belter, A | 1 |
| Gawrońska, I | 1 |
| Giel-Pietraszuk, M | 1 |
| Naskręt-Barciszewska, MZ | 1 |
| Wu, J | 1 |
| Zhang, H | 1 |
| Xu, Y | 1 |
| Zhang, J | 1 |
| Zhu, W | 1 |
| Zhang, Y | 1 |
| Chen, L | 1 |
| Hua, W | 1 |
| Mao, Y | 1 |
| Wang, J | 1 |
| Liu, K | 1 |
| Wang, XF | 1 |
| Sun, DJ | 1 |
| Pavan, V | 1 |
| Ribaudo, G | 1 |
| Zorzan, M | 1 |
| Redaelli, M | 1 |
| Pezzani, R | 1 |
| Mucignat-Caretta, C | 1 |
| Zagotto, G | 1 |
4 other studies available for juglone and Brain Neoplasms
| Article | Year |
|---|---|
Juglone in Combination with Temozolomide Shows a Promising Epigenetic Therapeutic Effect on the Glioblastoma Cell Line.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Epi | 2023 |
Juglone induces apoptosis of tumor stem-like cells through ROS-p38 pathway in glioblastoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Gliobla | 2017 |
Juglone reduces growth and migration of U251 glioblastoma cells and disrupts angiogenesis.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cell Movem | 2017 |
Antiproliferative activity of Juglone derivatives on rat glioma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proli | 2017 |