juglone has been researched along with B16 Melanoma in 4 studies
juglone: structure
juglone : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study demonstrates cytotoxic and genotoxic potential of juglone, a chief constituent of walnut, and its underlying mechanisms against melanoma cells." | 7.75 | Juglone, a naphthoquinone from walnut, exerts cytotoxic and genotoxic effects against cultured melanoma tumor cells. ( Aithal, BK; Kumar, MR; Rao, BN; Rao, BS; Udupa, N, 2009) |
| "This study demonstrates cytotoxic and genotoxic potential of juglone, a chief constituent of walnut, and its underlying mechanisms against melanoma cells." | 3.75 | Juglone, a naphthoquinone from walnut, exerts cytotoxic and genotoxic effects against cultured melanoma tumor cells. ( Aithal, BK; Kumar, MR; Rao, BN; Rao, BS; Udupa, N, 2009) |
| "Juglone pretreatment before radiation also resulted in a significant elevation in the intracellular reactive oxygen species levels compared with radiation alone." | 1.38 | Tumor growth inhibitory effect of juglone and its radiation sensitizing potential: in vivo and in vitro studies. ( Aithal, KB; Kumar, S; Rao, BN; Rao, SB; Udupa, N, 2012) |
| " In vitro cytotoxicity studies against melanoma cells indicated that liposomal juglone was more toxic than free juglone." | 1.37 | Evaluation of pharmacokinetic, biodistribution, pharmacodynamic, and toxicity profile of free juglone and its sterically stabilized liposomes. ( Aithal, BK; Arumugam, K; Prabhu, V; Rao, BN; Sajankila, SP; Satish Rao, BS; Satyamoorthy, K; Shavi, G; Sunil Kumar, MR; Udupa, N; Upadhya, R, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, W | 1 |
| Bao, J | 1 |
| Lin, W | 1 |
| Gao, H | 1 |
| Zhao, W | 1 |
| Zhang, Q | 1 |
| Leung, CH | 1 |
| Ma, DL | 1 |
| Lu, J | 1 |
| Chen, X | 1 |
| Aithal, BK | 2 |
| Kumar, MR | 1 |
| Rao, BN | 3 |
| Udupa, N | 3 |
| Rao, BS | 1 |
| Aithal, KB | 1 |
| Kumar, S | 1 |
| Rao, SB | 1 |
| Sunil Kumar, MR | 1 |
| Upadhya, R | 1 |
| Prabhu, V | 1 |
| Shavi, G | 1 |
| Arumugam, K | 1 |
| Sajankila, SP | 1 |
| Satyamoorthy, K | 1 |
| Satish Rao, BS | 1 |
4 other studies available for juglone and B16 Melanoma
| Article | Year |
|---|---|
2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Glutathione; Humans; Hydrogen Peroxide; JNK Mitogen-Activated | 2016 |
Juglone, a naphthoquinone from walnut, exerts cytotoxic and genotoxic effects against cultured melanoma tumor cells.
Topics: Animals; Annexin A5; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; DNA Fragment | 2009 |
Tumor growth inhibitory effect of juglone and its radiation sensitizing potential: in vivo and in vitro studies.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Survival; DNA Damage; Female; Male; Melanoma, Experi | 2012 |
Evaluation of pharmacokinetic, biodistribution, pharmacodynamic, and toxicity profile of free juglone and its sterically stabilized liposomes.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Female; | 2011 |