juglone has been researched along with Amyotrophic Lateral Sclerosis in 1 studies
juglone: structure
juglone : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kesavapany, S | 1 |
| Patel, V | 1 |
| Zheng, YL | 1 |
| Pareek, TK | 1 |
| Bjelogrlic, M | 1 |
| Albers, W | 1 |
| Amin, N | 1 |
| Jaffe, H | 1 |
| Gutkind, JS | 1 |
| Strong, MJ | 1 |
| Grant, P | 1 |
| Pant, HC | 1 |
1 other study available for juglone and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Inhibition of Pin1 reduces glutamate-induced perikaryal accumulation of phosphorylated neurofilament-H in neurons.
Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Cell Nucleus; Ganglia, Spinal; | 2007 |