jtp 4819 has been researched along with Alzheimer Disease in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benoist, A; De Nanteuil, G; Hervé, Y; Lepagnol, J; Portevin, B; Rémond, G; Vincent, M | 1 |
| Fujiwara, T; Iwamoto, Y; Kato, T; Okamiya, K; Shinoda, M; Toide, K | 1 |
| Fujiwara, T; Iwamoto, Y; Okamiya, K; Shinoda, M; Toide, K; Uemura, A | 1 |
| Fujiwara, T; Iwamoto, Y; Shinoda, M; Toide, K | 1 |
| Miyazaki, A; Shinoda, M; Toide, K | 1 |
1 review(s) available for jtp 4819 and Alzheimer Disease
| Article | Year |
|---|---|
A novel prolyl endopeptidase inhibitor, JTP-4819--its behavioral and neurochemical properties for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Prolyl Oligopeptidases; Pyrrolidines; Rats; Serine Endopeptidases; Serine Proteinase Inhibitors | 1998 |
4 other study(ies) available for jtp 4819 and Alzheimer Disease
| Article | Year |
|---|---|
New prolyl endopeptidase inhibitors: in vitro and in vivo activities of azabicyclo[2.2.2]octane, azabicyclo[2.2.1]heptane, and perhydroindole derivatives.
Topics: Alzheimer Disease; Amino Acid Sequence; Amnesia; Animals; Avoidance Learning; Bridged Bicyclo Compounds, Heterocyclic; Drug Design; Drug Evaluation, Preclinical; Humans; Molecular Conformation; Molecular Sequence Data; Nerve Tissue Proteins; Prolyl Oligopeptidases; Pyrroles; Rats; Scopolamine; Serine Endopeptidases; Serine Proteinase Inhibitors; Structure-Activity Relationship | 1996 |
Effect of a novel prolyl endopeptidase inhibitor, JTP-4819, on neuropeptide metabolism in the rat brain.
Topics: Administration, Oral; Alzheimer Disease; Animals; Arginine Vasopressin; Cerebral Cortex; Dose-Response Relationship, Drug; Hippocampus; Neuropeptides; Prolyl Oligopeptidases; Pyrrolidines; Rats; Rats, Wistar; Serine Endopeptidases; Serine Proteinase Inhibitors; Substance P; Thyrotropin-Releasing Hormone | 1996 |
A novel prolyl endopeptidase inhibitor, JTP-4819, with potential for treating Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Avoidance Learning; Brain Chemistry; Brain Ischemia; Dose-Response Relationship, Drug; Maze Learning; Microdialysis; Neuropeptides; Nootropic Agents; Prolyl Oligopeptidases; Protease Inhibitors; Pyrrolidines; Rats; Serine Endopeptidases | 1997 |
Effect of a novel prolyl endopeptidase inhibitor, JTP-4819, on spatial memory and central cholinergic neurons in aged rats.
Topics: Acetylcholine; Aging; Alzheimer Disease; Animals; Cerebral Cortex; Choline O-Acetyltransferase; Drug Evaluation, Preclinical; Hippocampus; Male; Maze Learning; Memory; Neurons; Prolyl Oligopeptidases; Pyrrolidines; Rats; Rats, Inbred F344; Serine Endopeptidases; Serine Proteinase Inhibitors | 1997 |