Page last updated: 2024-09-05

jtp 4819 and Aging

jtp 4819 has been researched along with Aging in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jalkanen, AJ; Jarho, EM; Mannila, A; Männistö, PT; Puttonen, KA; Ruotsalainen, S; Sinervä, V; Venäläinen, JI; Wallén, EA1
Iwamoto, Y; Kato, T; Okamiya, K; Toide, K1
Abe, H; Fujiwara, T; Iwamoto, Y; Toide, K1
Okamiya, K; Shinoda, M; Toide, K1
Fujiwara, T; Iwamoto, Y; Shinoda, M; Toide, K1

Other Studies

5 other study(ies) available for jtp 4819 and Aging

ArticleYear
Beneficial effect of prolyl oligopeptidase inhibition on spatial memory in young but not in old scopolamine-treated rats.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 100, Issue:2

    Topics: Aging; Amnesia; Animals; Frontal Lobe; Hippocampus; Hypothalamus; Inositol 1,4,5-Trisphosphate; Male; Maze Learning; Memory; Motor Activity; Muscarinic Antagonists; Neurotensin; Prolyl Oligopeptidases; Pyrrolidines; Rats; Rats, Wistar; Scopolamine; Serine Endopeptidases; Serine Proteinase Inhibitors; Substance P

2007
Effect of a novel prolyl endopeptidase inhibitor, JTP-4819, on prolyl endopeptidase activity and substance P- and arginine-vasopressin-like immunoreactivity in the brains of aged rats.
    Journal of neurochemistry, 1995, Volume: 65, Issue:1

    Topics: Aging; Animals; Arginine Vasopressin; Cerebral Cortex; Diterpenes; Hippocampus; Immunoenzyme Techniques; Male; Phorbol Esters; Prolyl Oligopeptidases; Pyrrolidines; Rats; Rats, Inbred F344; Rats, Wistar; Serine Endopeptidases; Serine Proteinase Inhibitors; Substance P

1995
JTP-4819: a novel prolyl endopeptidase inhibitor with potential as a cognitive enhancer.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:3

    Topics: Acetylcholine; Aging; Animals; Avoidance Learning; Cognition; Cognition Disorders; Flavobacterium; Frontal Lobe; Hippocampus; Hydrolysis; Male; Microdialysis; Neuropeptides; Prolyl Oligopeptidases; Pyrrolidines; Rats; Rats, Inbred F344; Rats, Wistar; Scopolamine; Serine Endopeptidases; Serine Proteinase Inhibitors; Substrate Specificity

1995
Effect of a novel prolyl endopeptidase inhibitor, JTP-4819, on thyrotropin-releasing hormone-like immunoreactivity in the cerebral cortex and hippocampus of aged rats.
    Japanese journal of pharmacology, 1995, Volume: 69, Issue:3

    Topics: Aging; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hippocampus; Immunohistochemistry; Male; Pyrrolidines; Rats; Rats, Inbred F344; Thyrotropin-Releasing Hormone

1995
Effect of a novel prolyl endopeptidase inhibitor, JTP-4819, on spatial memory and central cholinergic neurons in aged rats.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 56, Issue:3

    Topics: Acetylcholine; Aging; Alzheimer Disease; Animals; Cerebral Cortex; Choline O-Acetyltransferase; Drug Evaluation, Preclinical; Hippocampus; Male; Maze Learning; Memory; Neurons; Prolyl Oligopeptidases; Pyrrolidines; Rats; Rats, Inbred F344; Serine Endopeptidases; Serine Proteinase Inhibitors

1997