josamycin and Respiratory-Tract-Infections

josamycin has been researched along with Respiratory-Tract-Infections* in 2 studies

Other Studies

2 other study(ies) available for josamycin and Respiratory-Tract-Infections

ArticleYear
Antimicrobial susceptibility of Mycoplasma pneumoniae isolates and molecular analysis of macrolide-resistant strains from Shanghai, China.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5

    Fifty-three Mycoplasma pneumoniae strains were isolated from pediatric patients in Shanghai, China, from October 2005 to February 2008. Of 53 clinical isolates, 44 (83%) were resistant to erythromycin (MICs of >128 microg/ml for all 44 strains), azithromycin, and clarithromycin. All macrolide-resistant M. pneumoniae strains harbored an A-to-G transition mutation at position 2063 in 23S rRNA genes. Forty-five (85%) clinical isolates were classified into the P1 gene restriction fragment length polymorphism type I, and six (11%) were type II.

    Topics: Adhesins, Bacterial; Anti-Bacterial Agents; Child; China; Drug Resistance, Bacterial; Genes, rRNA; Humans; Macrolides; Microbial Sensitivity Tests; Mutation; Mycoplasma pneumoniae; Pneumonia, Mycoplasma; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Respiratory Tract Infections; RNA, Ribosomal, 23S; Sequence Analysis, DNA

2009
Molecular mechanisms of macrolide resistance in clinical isolates of Mycoplasma pneumoniae from China.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5

    Fifty clinical Mycoplasma pneumoniae strains were isolated from 370 children with respiratory tract infections. Four strains were susceptible to macrolides, while the other 46 (92%) were macrolide resistant. The molecular mechanism of resistance was shown to be associated with point mutations in 23S rRNA at positions 2063 and 2064.

    Topics: Anti-Bacterial Agents; Child; China; Drug Resistance, Bacterial; Humans; Macrolides; Microbial Sensitivity Tests; Mycoplasma pneumoniae; Pneumonia, Mycoplasma; Point Mutation; Respiratory Tract Infections; RNA, Ribosomal, 23S

2009