jnj-7777120 and Nerve-Degeneration

jnj-7777120 has been researched along with Nerve-Degeneration* in 1 studies

Other Studies

1 other study(ies) available for jnj-7777120 and Nerve-Degeneration

ArticleYear
Histamine-4 receptor antagonist JNJ7777120 inhibits pro-inflammatory microglia and prevents the progression of Parkinson-like pathology and behaviour in a rat model.
    Brain, behavior, and immunity, 2019, Volume: 76

    The activation of microglial cells is presumed to play a key role in the pathogenesis of Parkinson's disease (PD). The activity of microglia is regulated by the histamine-4 receptor (H

    Topics: alpha-Synuclein; Animals; Behavior, Animal; Brain; Corpus Striatum; Disease Models, Animal; Disease Progression; Dopaminergic Neurons; Histamine; Indoles; Inflammation; Male; Microglia; Nerve Degeneration; Parkinson Disease; Parkinsonian Disorders; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Histamine H4; Rotenone

2019