ivabradine has been researched along with Heart Disease, Ischemic in 68 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 31 (45.59) | 29.6817 |
| 2010's | 34 (50.00) | 24.3611 |
| 2020's | 3 (4.41) | 2.80 |
| Authors | Studies |
|---|---|
| Cuisiat, F; Le Grand, B; Létienne, R; Mas, A; Pignier, C; Rolland, F; Vacher, B | 1 |
| Chen, T; Fang, X; Huang, J; Xu, X; Zhao, Q; Zheng, J; Zhu, H | 1 |
| Belenkov, YN; Ilgisonis, IS; Naymann, YI; Privalova, EA; Zhito, AV | 1 |
| DiDomenico, RJ; Griffin, T; Hellenbart, EL | 1 |
| Dalla Vecchia, LA; De Maria, B; Perego, F | 1 |
| Bangalore, S; Chen, C; Godoy, LC; Kaur, G; Mehta, PK; Morrone, D; Sidhu, MS | 1 |
| Kiyakbaev, GK; Kobalava, ZD; Shavarov, AA | 1 |
| Bakkehaug, JP; How, OJ; Kildal, AB; Myrmel, T; Rødland, L; Rønning, L | 1 |
| Lyon, AR; Ng, FS; Peters, NS; Shadi, IT | 1 |
| Jacobshagen, C | 1 |
| Chichkanov, GG; Tsorin, IB | 1 |
| Li, L; Peng, L; Song, A; Wang, G; Yan, B; Zeng, L | 1 |
| Garganeeva, AA; Shabanova, MV | 1 |
| Caetano, J; Delgado Alves, J | 1 |
| Angelini, L; Battistoni, I; Perna, GP | 1 |
| Ilashchuk, T; Okipniak, I; Shirokova, S | 1 |
| Freedman, B; Gedik, N; Heusch, G; Kleinbongard, P; Klöcker, N; Witting, P | 1 |
| Glezer, MG | 1 |
| Lopatin, YM | 1 |
| Cacciapuoti, F | 1 |
| Heusch, G; Kleinbongard, P | 1 |
| Colombo, A; Fragasso, G; Fumero, A; Giannini, F; Godino, C; Maranta, F; Margonato, A; Oppizzi, M; Slavich, M | 1 |
| Bakkehaug, JP; How, OJ; Kildal, AB; Myrmel, T; Naesheim, T; Torgersen Engstad, E | 1 |
| Abreu-Gonzalez, P; Dominguez-Rodriguez, A | 1 |
| Allen, CJ; Guha, K; Hartley, A; Sharma, R | 1 |
| Arkad'eva, NM; Bakshiev, VI; Kolomoets, NM; Kostycheva, TV; Usenko, SV; Uvaĭsova, KU; Zarubina, EG | 1 |
| Arora, R; Jawad, E | 1 |
| Anderzhanova, AA; Dranko, ON; Makolkin, VI; Petriĭ, VV | 1 |
| van de Borne, P | 1 |
| Belhani, D; Bricca, G; Bui-Xuan, B; Chevalier, P; Descotes, J; Manati, W; Tabib, A; Timour, Q; Vaillant, F | 1 |
| Bertolazzi, M; Macciò, S; Rognoni, A; Rognoni, G | 1 |
| Abreu-Gonzalez, P; Bosa-Ojeda, F; Consuegra-Sanchez, L; Dominguez-Rodriguez, A; Fard, SS; Grande, AS; Jiménez-Sosa, A; Kaski, JC | 1 |
| Fomin, IV; Valikulova, FIu | 1 |
| Cargnoni, A; Ceconi, C; Ferrari, R; Francolini, G; Parinello, G | 1 |
| Filipovský, J | 1 |
| Biriuchenko, MV; Kapelovich, VIu; Kupaeva, RA; Pozdniakova, NV; Sekerko, SA; Tatarchenko, IP | 1 |
| Gewirtz, H | 1 |
| Grigor'eva, NIu | 1 |
| Heusch, G | 3 |
| Rosano, GM; Vitale, C; Volterrani, M | 1 |
| Bugatti, S; Dei Cas, L; Lombardi, C; Metra, M; Zacà, V | 1 |
| Kolosova, MV; Komlev, AD; Kuzenkova, VE; Kuziaev, AI; Laskin, GM | 1 |
| Abuladze, GV; Chachua, TB; Dundua, GI; Kvirkveliia, AA; Nebieridze, MI | 1 |
| Ferrari, R; Fox, KM | 1 |
| Belhani, D; Bui-Xuan, B; Chevalier, P; Dehina, L; Descotes, J; Mazzadi, A; Riera, C; Tabib, A; Timour, Q; Vaillant, F | 1 |
| Bonadei, I; Bontempi, L; Curnis, A; D'Aloia, A; Dei Cas, L; Del Magro, F; Piovanelli, B; Vizzardi, E | 1 |
| Bui-Xuan, B; Chevalier, P; Dehina, L; Descotes, J; Dizerens, N; Lauzier, B; Tabib, A; Timour, Q; Vaillant, F | 1 |
| Brambilla, G; Dei Cas, L; Della Pina, P; Gavazzoni, M; Gorga, E; Raddino, R; Regazzoni, V | 1 |
| Riccioni, G | 2 |
| Borer, JS; Fox, K; Jaillon, P; Lerebours, G | 1 |
| Bidouard, JP; Lesage, L; Péglion, JL; Reure, H; Vilaine, JP | 1 |
| Berdeaux, A; Colin, P; Ghaleh, B; Giudicelli, JF; Hittinger, L; Monnet, X | 1 |
| Vilaine, JP | 2 |
| Borer, JS | 1 |
| Fox, K | 1 |
| Eliseev, OM | 1 |
| Ford, I; Fox, KM; Ruzyllo, W; Tendera, M | 1 |
| Borer, JS; DiFrancesco, D | 1 |
| Berdeaux, A | 1 |
| Chaitman, BR; Sano, J | 1 |
| Arkad'eva, NM; Baksheev, VI; Kartashov, VT; Kolomoets, NM; Kostycheva, TV; Shvediuk, VM; Zarubina, EG | 1 |
| Baksheev, VI; Kolomoets, NM; Zarubina, EG | 1 |
| Berdeaux, A; Colin, P; de Curzon, OP; Ghaleh, B; Giudicelli, JF; Monnet, X | 1 |
29 review(s) available for ivabradine and Heart Disease, Ischemic
| Article | Year |
|---|---|
Effects of the Antianginal Drugs Ranolazine, Nicorandil, and Ivabradine on Coronary Microvascular Function in Patients With Nonobstructive Coronary Artery Disease: A Meta-analysis of Randomized Controlled Trials.
Topics: Angina Pectoris; Cardiovascular Agents; Coronary Artery Disease; Humans; Ivabradine; Myocardial Ischemia; Nicorandil; Randomized Controlled Trials as Topic; Ranolazine; Treatment Outcome | 2019 |
Beyond Heart Failure and Ischemic Heart Disease: A Scoping Review of Novel Uses of Ivabradine in Adults.
Topics: Adult; Cardiovascular Agents; Heart Failure; Heart Rate; Humans; Ivabradine; Myocardial Ischemia; Sinoatrial Node | 2020 |
Ivabradine in Cardiovascular Disease Management Revisited: a Review.
Topics: Cardiovascular Agents; Cardiovascular Diseases; Humans; Ivabradine; Myocardial Ischemia; Prospective Studies; Randomized Controlled Trials as Topic; Stroke Volume; Tachycardia, Sinus | 2021 |
[Late sodium current and calcium overload--pathogenesis and adequate treatment].
Topics: Acetanilides; Adrenergic beta-Antagonists; Angina Pectoris; Atrial Fibrillation; Benzazepines; Calcium; Calcium Channel Blockers; Cardiovascular Agents; Coronary Artery Disease; Electrocardiography; Endothelium, Vascular; Heart Failure, Diastolic; Humans; Hypercalcemia; Ivabradine; Myocardial Ischemia; Nitrates; Piperazines; Ranolazine; Sodium; Sodium Channels; Sodium-Calcium Exchanger | 2013 |
[Heart rate reduction due to selective specific inhibition of the If current opens new possibilities in treatment of basic cardiovascular diseases].
Topics: Adrenergic beta-Antagonists; Animals; Atherosclerosis; Benzazepines; Cardiotonic Agents; Heart; Heart Failure; Heart Rate; Humans; Ivabradine; Myocardial Ischemia; Stroke Volume; Ventricular Dysfunction, Left | 2013 |
Ivabradine significantly improves cardiac function in patients with ischemic heart disease: a meta-analysis of randomized controlled trials.
Topics: Benzazepines; Humans; Ivabradine; Myocardial Ischemia; Randomized Controlled Trials as Topic; Recovery of Function; Treatment Outcome; Ventricular Function, Left | 2013 |
Heart rate and cardiovascular protection.
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Atherosclerosis; Benzazepines; Cardiovascular Agents; Clinical Trials as Topic; Heart Failure; Heart Rate; Humans; Hypertension; Ivabradine; Myocardial Ischemia; Risk Factors | 2015 |
[Heart rate modulation in stable ischemic heart disease: what we have learned from the SIGNIFY study?].
Topics: Benzazepines; Cardiovascular Diseases; Clinical Trials as Topic; Coronary Artery Disease; Drug Interactions; Heart Rate; Humans; Ivabradine; Myocardial Ischemia; Risk Factors; Treatment Outcome | 2015 |
Ranolazine and Ivabradine: two different modalities to act against ischemic heart disease.
Topics: Angina, Stable; Benzazepines; Cardiovascular Agents; Heart Rate; Humans; Ivabradine; Myocardial Ischemia; Oxygen Consumption; Ranolazine | 2016 |
Ivabradine: Cardioprotection By and Beyond Heart Rate Reduction.
Topics: Angina, Stable; Animals; Benzazepines; Cardiotonic Agents; Coronary Artery Disease; Heart Failure; Heart Rate; Humans; Ivabradine; Longevity; Mice; Myocardial Ischemia; Myocardial Reperfusion; Swine | 2016 |
Ivabradine: A Current Overview.
Topics: Animals; Benzazepines; Cardiovascular Agents; Heart Failure; Heart Rate; Humans; Ivabradine; Myocardial Ischemia; Ventricular Dysfunction, Left | 2016 |
Chronic stable angina pectoris.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetanilides; Angina Pectoris; Antihypertensive Agents; Benzazepines; Bosentan; Chronic Disease; Counterpulsation; Cyclic Nucleotide-Gated Cation Channels; Exercise Test; Heart Murmurs; Humans; Ivabradine; Myocardial Contraction; Myocardial Ischemia; Myocardial Revascularization; Myocardium; Nicorandil; Oxygen Consumption; Perhexiline; Piperazines; Protein Kinase Inhibitors; Ranolazine; Sulfonamides; Trimetazidine; Vasodilator Agents | 2008 |
[What are the alternatives to betablockers in 2009?].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Benzazepines; Cardiomyopathies; Heart Failure; Heart Valve Diseases; Humans; Ivabradine; Myocardial Infarction; Myocardial Ischemia; Patient Selection; Stereoisomerism; Vasodilator Agents | 2008 |
Ivabradine: cardiovascular effects.
Topics: Animals; Benzazepines; Cardiovascular Physiological Phenomena; Clinical Trials as Topic; Coronary Circulation; Coronary Disease; Heart Rate; Humans; Ivabradine; Myocardial Ischemia | 2009 |
Heart rate in ischemic heart disease. The innovation of ivabradine: more than pure heart rate reduction.
Topics: Adrenergic beta-Antagonists; Benzazepines; Cardiovascular Agents; Coronary Artery Disease; Heart Rate; Humans; Ivabradine; Myocardial Ischemia; Randomized Controlled Trials as Topic | 2010 |
[Heart rate: a risk factor or an epiphenomenon?].
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Benzazepines; Calcium Channel Blockers; Cohort Studies; Cyclic Nucleotide-Gated Cation Channels; Female; Follow-Up Studies; Heart Failure; Heart Rate; Hospitalization; Humans; Hypertension; Ivabradine; Male; Middle Aged; Multivariate Analysis; Myocardial Ischemia; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Stereoisomerism; Tachycardia; Time Factors; Ventricular Dysfunction, Left | 2010 |
Heart rate and heart failure. Not a simple relationship.
Topics: Animals; Benzazepines; Cardiac Pacing, Artificial; Coronary Artery Disease; Disease Models, Animal; Heart Failure; Heart Rate; Humans; Ivabradine; Models, Cardiovascular; Multicenter Studies as Topic; Myocardial Ischemia; Myocardium; Randomized Controlled Trials as Topic; Stress, Mechanical; Tachycardia; Tachycardia, Supraventricular; Treatment Outcome; Ventricular Dysfunction, Left; Vertebrates | 2011 |
Heart rate: a forgotten link in coronary artery disease?
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Arteriosclerosis; Benzazepines; Coronary Artery Disease; Coronary Vessels; Disease Progression; Elasticity; Endothelium, Vascular; Heart Rate; Hemodynamics; Humans; Ivabradine; Myocardial Ischemia; Myocardium; Oxygen Consumption | 2011 |
The importance of reducing heart rate in cardiovascular diseases: effects of Ivabradine.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Benzazepines; Cardiovascular Agents; Cardiovascular Diseases; Clinical Trials as Topic; Cyclic Nucleotide-Gated Cation Channels; Heart Failure; Heart Rate; Humans; Ivabradine; Myocardial Ischemia; Prognosis; Sinoatrial Node | 2011 |
[Pharmacological correction of heart rate in myocardial ischemia].
Topics: Action Potentials; Adrenergic beta-Antagonists; Benzazepines; Calcium Channel Blockers; Heart Rate; Humans; Ion Channels; Ivabradine; Myocardial Contraction; Myocardial Ischemia; Oxygen Consumption; Risk Factors | 2012 |
Ivabradine: an intelligent drug for the treatment of ischemic heart disease.
Topics: Angina, Stable; Animals; Benzazepines; Depression, Chemical; Heart; Heart Rate; Humans; Ivabradine; Myocardial Contraction; Myocardial Ischemia; Sinoatrial Node | 2012 |
Ivabradine: the hope for a good treatment of ischemic heart disease.
Topics: Angina, Stable; Benzazepines; Coronary Artery Disease; Humans; Ivabradine; Myocardial Ischemia | 2013 |
[The discovery of the selective If current inhibitor ivabradine (Procoralan): a new therapeutic approach to ischemic heart disease].
Topics: Benzazepines; Biological Clocks; Cardiotonic Agents; Coronary Disease; Electrophysiology; Humans; Ivabradine; Myocardial Ischemia | 2006 |
Therapeutic effects of I(f) blockade: evidence and perspective.
Topics: Angina Pectoris; Animals; Benzazepines; Heart Rate; Humans; Ion Channels; Ivabradine; Myocardial Ischemia; Randomized Controlled Trials as Topic; Ventricular Dysfunction, Left | 2006 |
The discovery of the selective I(f) current inhibitor ivabradine. A new therapeutic approach to ischemic heart disease.
Topics: Animals; Atrioventricular Node; Benzazepines; Depression, Chemical; Drug Evaluation, Preclinical; Heart Rate; Ion Channels; Ivabradine; Myocardial Contraction; Myocardial Ischemia; Physical Conditioning, Animal; Sinoatrial Node; Ventricular Function | 2006 |
The funny current: cellular basis for the control of heart rate.
Topics: Animals; Benzazepines; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Electrophysiology; Heart Rate; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ivabradine; Muscle Proteins; Myocardial Ischemia; Myocytes, Cardiac; Potassium Channels; Protein Isoforms; Sinoatrial Node | 2007 |
Preclinical results with I(f) current inhibition by ivabradine.
Topics: Animals; Benzazepines; Cardiac Output; Coronary Circulation; Cyclic Nucleotide-Gated Cation Channels; Drug Evaluation, Preclinical; Heart Conduction System; Heart Rate; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ivabradine; Mice; Muscle Proteins; Myocardial Contraction; Myocardial Ischemia; Myocardium; Potassium Channels; Rats; Stroke Volume; Ventricular Function, Left; Ventricular Remodeling | 2007 |
Heart rate in the pathophysiology of coronary blood flow and myocardial ischaemia: benefit from selective bradycardic agents.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Benzazepines; Coronary Circulation; Heart Rate; Humans; Ivabradine; Myocardial Ischemia | 2008 |
Novel therapeutic approaches to treating chronic angina in the setting of chronic ischemic heart disease.
Topics: Acetanilides; Adrenergic beta-Antagonists; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Calcium Channel Blockers; Chronic Disease; Enzyme Inhibitors; Humans; Ivabradine; Myocardial Ischemia; Nicorandil; Nitro Compounds; Piperazines; Ranolazine; rho-Associated Kinases; Sinoatrial Node; Trimetazidine; Vasodilator Agents | 2007 |
10 trial(s) available for ivabradine and Heart Disease, Ischemic
| Article | Year |
|---|---|
[The Use of Selective Inhibitor of If-Channels Ivabradine in Patients with Ischemic Heart Disease, Heart Failure with High Heart Rate].
Topics: Heart Failure; Heart Rate; Humans; Ivabradine; Myocardial Ischemia; Quality of Life | 2019 |
[Clinical efficiency of ivabradine in patients with cardiorespiratory pathology].
Topics: Benzazepines; Cyclic Nucleotide-Gated Cation Channels; Dose-Response Relationship, Drug; Echocardiography; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Humans; Ivabradine; Male; Middle Aged; Myocardial Ischemia; Pilot Projects; Pulmonary Disease, Chronic Obstructive; Pulmonary Wedge Pressure; Quality of Life; Stroke Volume; Treatment Outcome; Ventricular Function, Left | 2008 |
Randomised, double-blind, placebo-controlled trial of ivabradine in patients with acute coronary syndrome: effects of the If current inhibitor ivabradine on reduction of inflammation markers in patients with acute coronary syndrome--RIVIERA trial study de
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Benzazepines; Biomarkers; C-Reactive Protein; Double-Blind Method; Drug Administration Schedule; Endpoint Determination; Female; Heart Arrest; Humans; Inflammation; Ion Channels; Ivabradine; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Patient Admission | 2009 |
[Antianginal effect of long-term use of ivabradine in patients with ischemic heart disease and diabetes in ambulatory conditions].
Topics: Adrenergic Antagonists; Aged; Ambulatory Care; Angina Pectoris; Benzazepines; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Ivabradine; Male; Middle Aged; Myocardial Ischemia; Treatment Outcome | 2009 |
[Ivabradine in patients with stable ischemic heart disease and left ventricular systolic dysfunction: the results of the BEAUTIFUL study].
Topics: Benzazepines; Cardiotonic Agents; Double-Blind Method; Female; Heart Rate; Humans; Ivabradine; Male; Middle Aged; Myocardial Ischemia; Ventricular Dysfunction, Left | 2009 |
[Clinical efficacy of ivabradin and nebivolol addition in combined treatment of ischemic heart disease patients with left ventricular dysfunction].
Topics: Benzazepines; Benzopyrans; Dose-Response Relationship, Drug; Drug Therapy, Combination; Echocardiography, Doppler, Color; Electrocardiography; Ethanolamines; Follow-Up Studies; Humans; Ivabradine; Middle Aged; Myocardial Contraction; Myocardial Ischemia; Nebivolol; Platelet Aggregation Inhibitors; Stereoisomerism; Treatment Outcome; Vasodilator Agents; Ventricular Dysfunction, Left | 2008 |
[Effect of the I(f) channel blocker ivabradine on the parameters of external respiration function in patients with chronic obstructive pulmonary disease in its stable course period].
Topics: Aged; Benzazepines; Cardiovascular Agents; Cyclic Nucleotide-Gated Cation Channels; Electrocardiography; Female; Heart Rate; Humans; Ivabradine; Male; Middle Aged; Myocardial Ischemia; Pulmonary Disease, Chronic Obstructive; Respiration; Respiratory Function Tests | 2010 |
Antianginal and antiischemic effects of ivabradine, an I(f) inhibitor, in stable angina: a randomized, double-blind, multicentered, placebo-controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Benzazepines; Depression, Chemical; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Ivabradine; Male; Middle Aged; Myocardial Ischemia; Sinoatrial Node; Treatment Outcome; Vision Disorders | 2003 |
Antianginal efficacy and safety of ivabradine compared with amlodipine in patients with stable effort angina pectoris: a 3-month randomised, double-blind, multicentre, noninferiority trial.
Topics: Aged; Amlodipine; Angina Pectoris; Benzazepines; Blood Pressure; Calcium Channel Blockers; Cardiotonic Agents; Double-Blind Method; Electrocardiography; Exercise Tolerance; Female; Heart Rate; Humans; Ivabradine; Male; Middle Aged; Myocardial Ischemia; Nitrates | 2007 |
[Effect of ivabradin on mechanism of inter-ventricle interaction and respiratory function in conditions of cardio-respiratory pathology (results of Russian pilot study)].
Topics: Anti-Arrhythmia Agents; Benzazepines; Blood Pressure; Female; Heart Function Tests; Heart Rate; Humans; Ivabradine; Male; Middle Aged; Myocardial Ischemia; Pilot Projects; Pulmonary Disease, Chronic Obstructive; Respiratory Function Tests; Russia; Treatment Outcome; Ventricular Function | 2008 |
29 other study(ies) available for ivabradine and Heart Disease, Ischemic
| Article | Year |
|---|---|
Sodium late current blockers in ischemia reperfusion: is the bullet magic?
Topics: Animals; Dose-Response Relationship, Drug; Electrophysiology; Female; Guinea Pigs; Humans; Imaging, Three-Dimensional; Male; Models, Molecular; Molecular Structure; Myocardial Ischemia; Rabbits; Rats; Rats, Wistar; Reperfusion; Sodium Channel Blockers; Structure-Activity Relationship | 2008 |
A case of highly disabling orthostatic hypotension: when an integrated cardiac rehabilitation approach makes the difference.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Cardiac Rehabilitation; Cardiovascular Agents; Humans; Hypotension, Orthostatic; Ivabradine; Male; Myocardial Ischemia; Quality of Life; Standing Position; Tilt-Table Test; Time Factors | 2020 |
[A New Insight on Anti-Ischemic Action of Ivabradine in Patients With Stable Angina].
Topics: Angina, Stable; Benzazepines; Cardiovascular Agents; Heart Failure; Heart Rate; Hemodynamics; Humans; Ivabradine; Myocardial Ischemia; Sinoatrial Node | 2017 |
Opposite diastolic effects of omecamtiv mecarbil versus dobutamine and ivabradine co-treatment in pigs with acute ischemic heart failure.
Topics: Animals; Cardiotonic Agents; Cardiovascular Agents; Diastole; Dobutamine; Drug Therapy, Combination; Heart Failure; Ivabradine; Male; Myocardial Ischemia; Swine; Treatment Outcome; Urea | 2018 |
Selective heart rate reduction with ivabradine slows ischaemia-induced electrophysiological changes and reduces ischaemia-reperfusion-induced ventricular arrhythmias.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Heart Rate; Ivabradine; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Ventricular Fibrillation | 2013 |
[Effect of optimal pulse slowing therapy on the course of recovery period in patients with ischemic heart disease after surgical myocardial revascularization].
Topics: Benzazepines; Bisoprolol; Cardiovascular Agents; Comparative Effectiveness Research; Drug Monitoring; Drug Therapy, Combination; Exercise Tolerance; Female; Heart Rate; Humans; Ivabradine; Male; Middle Aged; Myocardial Ischemia; Myocardial Revascularization; Postoperative Complications; Tachycardia; Treatment Outcome | 2014 |
[The comparative effectiveness of beta-blockers and inhibitors of if-iodium using in patients with stable angina pectoris].
Topics: Adrenergic beta-Antagonists; Angina, Stable; Benzazepines; Bisoprolol; Carbazoles; Carvedilol; Electrocardiography; Female; Heart Rate; Humans; Ivabradine; Male; Middle Aged; Myocardial Ischemia; Propanolamines | 2015 |
Pleiotropic, heart rate-independent cardioprotection by ivabradine.
Topics: Animals; Benzazepines; Cardiotonic Agents; Cell Survival; Cells, Cultured; Heart Rate; Ivabradine; Male; Mice; Myocardial Ischemia; Myocytes, Cardiac | 2015 |
[Effect of Treatment With Ivabradine on Quality of Life of Patients With Ischemic Heart Disease: Results of the LINCOR Program].
Topics: Aged; Benzazepines; Cardiovascular Agents; Cyclic Nucleotide-Gated Cation Channels; Female; Follow-Up Studies; Humans; Ivabradine; Male; Myocardial Ischemia; Program Evaluation; Quality of Life; Retrospective Studies; Surveys and Questionnaires; Time Factors; Treatment Outcome | 2015 |
[Evaluation of the Antianginal Efficacy of Ivabradine In Patients With Ischemic Heart Disease Complicated by Heart Failure].
Topics: Adult; Aged; Aged, 80 and over; Angina, Stable; Benzazepines; Cardiovascular Agents; Cyclic Nucleotide-Gated Cation Channels; Female; Follow-Up Studies; Heart Rate; Humans; Ivabradine; Male; Middle Aged; Myocardial Ischemia; Treatment Outcome | 2015 |
Long-Term Preservation of Left Ventricular Systolic Function in Patients With Refractory Angina Pectoris and Inducible Myocardial Ischemia on Optimal Medical Therapy.
Topics: Aged; Angina Pectoris; Benzazepines; Cardiovascular Agents; Echocardiography; Exercise Test; Female; Follow-Up Studies; Humans; Ivabradine; Male; Myocardial Ischemia; Ranolazine; Retrospective Studies; Sodium Channel Blockers; Stroke Volume; Systole; Time Factors; Tomography, Emission-Computed, Single-Photon; Trimetazidine; Vasodilator Agents; Ventricular Function, Left | 2016 |
Reversing dobutamine-induced tachycardia using ivabradine increases stroke volume with neutral effect on cardiac energetics in left ventricular post-ischaemia dysfunction.
Topics: Animals; Benzazepines; Cardiac Output; Cardiotonic Agents; Coronary Circulation; Dobutamine; Energy Metabolism; Heart; Heart Rate; In Vitro Techniques; Ivabradine; Male; Mice; Myocardial Ischemia; Myocardium; Oxygen Consumption; Stroke Volume; Swine; Tachycardia; Ventricular Dysfunction, Left | 2016 |
Ivabradine and the anti-inflammatory effects in patients with ischemic heart disease.
Topics: Acute Coronary Syndrome; Aged; Anti-Arrhythmia Agents; Benzazepines; C-Reactive Protein; Coronary Circulation; Female; Heart Rate; Humans; Inflammation; Ivabradine; Male; Middle Aged; Myocardial Ischemia; Randomized Controlled Trials as Topic; Review Literature as Topic | 2016 |
[Experience of the use of ivabradine in clinical practice].
Topics: Adult; Aged; Benzazepines; Dose-Response Relationship, Drug; Electrocardiography; Exercise Test; Female; Follow-Up Studies; Humans; Ivabradine; Male; Middle Aged; Myocardial Ischemia; Stereoisomerism; Time Factors; Treatment Outcome | 2008 |
Ivabradine induces an increase in ventricular fibrillation threshold during acute myocardial ischemia: an experimental study.
Topics: Action Potentials; Acute Disease; Animals; Anti-Arrhythmia Agents; Benzazepines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Heart Conduction System; Heart Rate; Ivabradine; Male; Mitochondria, Heart; Myocardial Ischemia; Succinate Dehydrogenase; Sus scrofa; Time Factors; Ventricular Fibrillation; Ventricular Function, Left; Ventricular Pressure | 2008 |
Heart rate reduction with ivabradine improves energy metabolism and mechanical function of isolated ischaemic rabbit heart.
Topics: Adenosine Triphosphate; Animals; Benzazepines; Creatine Kinase; Cyclic Nucleotide-Gated Cation Channels; Energy Metabolism; Heart; Heart Rate; Ivabradine; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Norepinephrine; Rabbits | 2009 |
'Funny' current: if heart rate slowing is not the best answer, what might be?
Topics: Animals; Benzazepines; Cyclic Nucleotide-Gated Cation Channels; Energy Metabolism; Heart Rate; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channels; Ivabradine; Myocardial Ischemia; Rabbits; Ventricular Function, Left | 2009 |
[Efficacy of therapy with bisoprolol and ivabradine in patients with ischemic heart disease combined with chronic obstructive pulmonary disease assessment of parameters of 24-hour ECG monitoring].
Topics: Adrenergic beta-Antagonists; Aged; Benzazepines; Bisoprolol; Bronchoconstriction; Cyclic Nucleotide-Gated Cation Channels; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Humans; Ivabradine; Male; Middle Aged; Myocardial Ischemia; Pulmonary Disease, Chronic Obstructive; Treatment Outcome | 2009 |
A BEAUTIFUL lesson--ivabradine protects from ischaemia, but not from heart failure: through heart rate reduction or more?
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Coronary Artery Disease; Heart Failure; Humans; Ivabradine; Myocardial Ischemia; Retrospective Studies; Ventricular Dysfunction, Left | 2009 |
[Clinical-hemodynamic and anti-ischemic effects ivabradine and nebivolol ischemic heart disease with left ventricular dysfunction].
Topics: Adrenergic beta-1 Receptor Antagonists; Benzazepines; Benzopyrans; Electrocardiography; Ethanolamines; Female; Hemodynamics; Humans; Ivabradine; Male; Middle Aged; Myocardial Ischemia; Nebivolol; Treatment Outcome; Ventricular Dysfunction, Left | 2010 |
Heart rate reduction with ivabradine increases ischaemia-induced ventricular fibrillation threshold: role of myocyte structure and myocardial perfusion.
Topics: Animals; Benzazepines; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Conduction System; Heart Rate; Ivabradine; Mitochondria, Heart; Muscle Cells; Myocardial Ischemia; Positron-Emission Tomography; Swine; Ventricular Fibrillation | 2011 |
Ivabradine but not propranolol delays the time to onset of ischaemia-induced ventricular fibrillation by preserving myocardial metabolic energy status.
Topics: Animals; Anti-Arrhythmia Agents; Benzazepines; Cyclic Nucleotide-Gated Cation Channels; Disease Models, Animal; Energy Metabolism; Ivabradine; Male; Myocardial Ischemia; Myocardium; Propranolol; Resuscitation; Swine; Ventricular Fibrillation | 2013 |
[New pharmacological approaches to ischemic heart disease].
Topics: Acetanilides; Benzazepines; Humans; Ivabradine; Myocardial Ischemia; Piperazines; Ranolazine | 2012 |
Anti-ischemic effects of ivabradine, a selective heart rate-reducing agent, in exercise-induced myocardial ischemia in pigs.
Topics: Animals; Benzazepines; Blood Pressure; Female; Heart Rate; Ivabradine; Male; Myocardial Ischemia; Physical Exertion; Propranolol; Swine, Miniature | 2003 |
Heart rate reduction during exercise-induced myocardial ischaemia and stunning.
Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Atenolol; Benzazepines; Blood Pressure; Constriction; Coronary Circulation; Dogs; Heart Rate; Ivabradine; Myocardial Ischemia; Myocardial Stunning; Physical Exertion; Ventricular Function, Left | 2004 |
Selective and specific I(f) inhibition: new perspectives for the treatment of stable angina.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Animals; Benzazepines; Calcium Channel Blockers; Cardiovascular Agents; Drug Administration Schedule; Drug Evaluation, Preclinical; Drug Therapy, Combination; Heart Rate; Humans; Ivabradine; Myocardial Ischemia; Nitrates; Randomized Controlled Trials as Topic; Sinoatrial Node | 2006 |
[Ivabradin (coraxan). One more new approach to fighting myocardial ischemia in patients with ischemic heart disease].
Topics: Animals; Benzazepines; Heart Rate; Humans; Ivabradine; Myocardial Ischemia; Stereoisomerism; Treatment Outcome | 2006 |
[Clinical efficacy of ivabradine in patients with ischemic heart disease in combination with chronic obstructive pulmonary disease].
Topics: Benzazepines; Dose-Response Relationship, Drug; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Humans; Ivabradine; Male; Middle Aged; Myocardial Ischemia; Pulmonary Disease, Chronic Obstructive; Quality of Life; Respiratory Function Tests; Stereoisomerism; Treatment Outcome | 2008 |
Effects of heart rate reduction with ivabradine on exercise-induced myocardial ischemia and stunning.
Topics: Animals; Benzazepines; Cardiotonic Agents; Dogs; Heart Rate; Ivabradine; Myocardial Contraction; Myocardial Ischemia; Myocardial Stunning; Physical Conditioning, Animal; Regional Blood Flow | 2001 |