ivabradine has been researched along with Cardiovascular Stroke in 61 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 19 (31.15) | 29.6817 |
| 2010's | 32 (52.46) | 24.3611 |
| 2020's | 10 (16.39) | 2.80 |
| Authors | Studies |
|---|---|
| Bertero, A; Cain, K; Dupras, S; El-Nachef, D; Futakuchi-Tsuchida, A; Jayabalu, A; Kalucki, FA; Kattman, S; Knollmann, BC; MacLellan, WR; Marchianò, S; Murry, CE; Nakamura, DS; Nakamura, K; Neidig, LE; Pabon, L; Reinecke, H; Robinson, MR; Thies, RS; Tian, R; Tsuchida, H; Weber, GJ; Whittington, D; Yang, X | 1 |
| Gluud, C; Jakobsen, JC; Liang, N; Maagaard, M; Nielsen, EE; Sethi, NJ; Yang, SH | 1 |
| Mackiewicz, U; Mączewski, M; Marciszek, M; Oknińska, M; Paterek, A | 1 |
| Adamcova, M; Aziriova, S; Baka, T; Krajcirovicova, K; Paulis, L; Repova, K; Simko, F | 1 |
| Abe, K; Furusawa, S; Ide, T; Ikeda, M; Ikeda, S; Ishikita, A; Ishimaru, K; Matsushima, S; Miyamoto, HD; Okabe, K; Tadokoro, T; Tsutsui, H | 1 |
| Botana, L; Diez-Mata, J; Hernandez, I; Ramirez-Carracedo, R; Sanchez, S; Saura, M; Tesoro, L; Zamorano, JL; Zaragoza, C | 1 |
| Chen, J; Chen, Q; Chen, S; Wang, B; Wang, Q; Yang, S; Zhang, X | 1 |
| Chen, Y; Dai, Y; Li, X; Wei, G; Zha, L | 1 |
| Sun, S; Yi, S; Zhang, Y | 1 |
| Castejón, B; Pascual Izco, M; Piedras, MJ; Sanmartín, M; Zamorano, JL; Zaragoza, C | 1 |
| Abe, K; Arimura, T; Kamada, K; Kishi, T; Mannoji, H; Nishikawa, T; Saku, K; Sunagawa, G; Sunagawa, K; Tsutsui, H | 1 |
| Alonso Salinas, GL; Castejón Navarro, B; Cuadrado Berrocal, I; Díez, J; Hernández Navarro, I; Largo Aramburu, C; Osorio Ruiz, Á; Pascual Izco, M; Ramírez-Carracedo, R; Sanmartín, M; Saura Redondo, M; Zamorano, JL; Zaragoza, C | 1 |
| Chen, S; Wu, X; Wu, Z; Ye, F; You, W | 1 |
| Abrahamsson, P; Böhm, M; Borer, JS; Ford, I; Kober, L; Komajda, M; Lloyd, SM; Metra, M; Swedberg, K; Tavazzi, L | 1 |
| Böhm, M; Borer, JS; Ferrari, R; Ford, I; Fox, K; Komajda, M; Robertson, M; Steg, PG; Swedberg, K; Tavazzi, L; Tendera, M | 1 |
| Glezer, MG | 1 |
| Goicolea, J; Hamon, M; Lopez-de-Sà, E; Lopez-Sendon, JL; Meinertz, T; Schiele, F; Steg, P; Werdan, K | 1 |
| Bonnet, J; Chasseriaud, W; Cochet, H; Coste, P; Douard, H; Gerbaud, E; Gilbert, S; Horovitz, A; Montaudon, M; Pucheu, Y | 1 |
| Chu, S; Dobrzynski, H; Duda, M; Gerges, JY; Lewartowski, B; Mackiewicz, U; Mączewski, M | 1 |
| Kositsyna, IV; Tereshchenko, SN; Uskach, TM | 1 |
| Asrar Ul Haq, M; Mutha, V; Rudd, N; Subiakto, I; Van Gaal, WJ | 1 |
| Bogatyryov, Y; Christensen, LP; Dedkov, EI; McCooey, DS; Tomanek, RJ; Weiss, RM | 1 |
| Hampton, T | 1 |
| D'iakov, IN; Glezer, MG | 1 |
| Böhm, M; Borer, JS; Ford, I; Kindermann, I; Komajda, M; Lainscak, M; Maack, C; Robertson, M; Swedberg, K; Tavazzi, L | 1 |
| Hu, D; Sun, Y; Yu, J | 1 |
| Nguyen, E; Weeda, ER; White, CM | 1 |
| Beyers, RJ; French, BA; Hossack, JA; Lin, D; O'Connor, DM; Piras, BA; Smith, RS | 1 |
| Cao, X; Li, X; Sun, Z; Xia, H; Zhang, B | 1 |
| Astashkin On Behalf Of The Linkor Study Investigators, EI; Glezer, MG | 1 |
| D'iachkov, VA; Germanov, AV; Golovin, EA; Shchukin, IuV; Surkova, EA; Vachev, AN | 1 |
| Ferrari, R; Ford, I; Fox, K; Steg, PG; Tendera, M | 2 |
| Gres, P; Heusch, G; Schilawa, D; Schulz, R; Skyschally, A; van Caster, P | 1 |
| Golubev, AV; Kositsyna, IV; Tereshchenko, SN | 1 |
| Heusch, G | 1 |
| van de Borne, P | 1 |
| Delcayre, C; Messaoudi, S; Milliez, P; Nehme, J; Rodriguez, C; Samuel, JL | 1 |
| Goris, M; Henning, RH; Schoemaker, RG; Ulu, N; van Gilst, WH | 1 |
| Abreu-Gonzalez, P; Bosa-Ojeda, F; Consuegra-Sanchez, L; Dominguez-Rodriguez, A; Fard, SS; Grande, AS; Jiménez-Sosa, A; Kaski, JC | 1 |
| Campanelli, JJ; Christensen, LP; Dedkov, EI; Tomanek, RJ; Weiss, RM; Zhang, RL; Zheng, W | 1 |
| Ferrari, R; Ford, I; Fox, K; Robertson, M; Steg, PG; Tendera, M | 1 |
| Cannizzaro, S; Di Pasquale, P; Fasullo, S; Ganci, F; Giambanco, F; Maringhini, G; Migliore, G; Paterna, S; Pinto, V; Sarullo, FM; Torres, D; Vitale, G | 1 |
| Berdeaux, A; Bruneval, P; Chetboul, V; Couvreur, N; Ghaleh, B; Gouni, V; Mandet, C; Pons, S; Pouchelon, JL; Tissier, R | 1 |
| Christensen, LP; Tomanek, RJ; Zhang, RL | 1 |
| Akchurin, RS; Chernova, NA; Erastova, NV; Grishin, IR; Karpov, IuA; Latypov, RS; Lopukhova, VV; Mareev, IuV; Saidova, MA; Sapel'nikov, OV | 1 |
| Lebedev, EV; Shkol'nik, EL; Vasiuk, IuA | 1 |
| Bouly, M; Ceconi, C; Cerbai, E; Comini, L; Ferrari, R; Mugelli, A; Stillitano, F; Suffredini, S | 1 |
| Ahmed, D; Clark, AL; Cleland, JG; Coletta, AP; Torabi, A | 1 |
| Feola, M; Lombardo, E; Menditto, E; Nervo, E; Piccolo, S; Taglieri, C | 1 |
| Bouly, M; Brogioni, S; Ceconi, C; Cerbai, E; Comini, L; Ferrari, R; Mugelli, A; Stillitano, F; Suffredini, S | 1 |
| Brakenhielm, E; Debunne, M; Fang, Y; Henry, JP; Lallemand, F; Mulder, P; Richard, V; Thuillez, C; Vercauteren, M | 1 |
| Abdulazizov, OSh; Diachuk, LI; Kiiakbaev, GK; Kobalava, ZhD; Moiseev, VS; Potapenko, AV | 1 |
| Kauffels, A; Lee, IO; Schilling, MK; Slotta, JE | 1 |
| Athanasiadis, A; Sechtem, U | 1 |
| Barbier, S; Chagraoui, A; Henry, JP; Lallemand, F; Lerebours, G; Mahlberg-Gaudin, F; Mulder, P; Renet, S; Richard, V; Thuillez, C | 1 |
| Er, F; Hoppe, UC | 1 |
| Hennersdorf, MG | 1 |
| Brockert, M; Gams, E; Langenbach, MR; Pomblum, VJ; Schepan, M; Schipke, JD; Schmitz-Spanke, S; Zirngibl, H | 1 |
| Christensen, LP; Dedkov, EI; Mahlberg-Gaudin, F; Tomanek, RJ; Weiss, RM; Zheng, W | 1 |
| Mackiewicz, U; Maczewski, M | 1 |
7 review(s) available for ivabradine and Cardiovascular Stroke
| Article | Year |
|---|---|
Ivabradine added to usual care in patients with heart failure: a systematic review with meta-analysis and trial sequential analysis.
Topics: Atrial Fibrillation; Bradycardia; Heart Failure; Humans; Ivabradine; Myocardial Infarction; Quality of Life | 2022 |
Effectiveness and safety of ivabradine in the treatment of acute myocardial infarction: a systematic review and meta-analysis.
Topics: China; Humans; Ivabradine; Myocardial Infarction; Stroke Volume | 2021 |
Effect of ivabradine in patients with left-ventricular systolic dysfunction: a pooled analysis of individual patient data from the BEAUTIFUL and SHIFT trials.
Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Cardiotonic Agents; Coronary Artery Disease; Female; Heart Failure; Heart Rate; Hospitalization; Humans; Ivabradine; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Randomized Controlled Trials as Topic; Treatment Outcome; Ventricular Dysfunction, Left | 2013 |
[Ivabradine in acute myocardial infarction].
Topics: Anti-Arrhythmia Agents; Benzazepines; Clinical Trials as Topic; Heart Rate; Humans; Ivabradine; Myocardial Infarction; Tachycardia; Treatment Outcome | 2014 |
Role of Ivabradine in the Treatment of Patients With Cardiovascular Disease.
Topics: Angina Pectoris; Benzazepines; Canada; Cardiovascular Diseases; Coronary Artery Disease; Female; Heart Failure, Systolic; Heart Rate; Humans; Ivabradine; Male; Myocardial Infarction; Stroke Volume; Treatment Outcome | 2016 |
[What are the alternatives to betablockers in 2009?].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Benzazepines; Cardiomyopathies; Heart Failure; Heart Valve Diseases; Humans; Ivabradine; Myocardial Infarction; Myocardial Ischemia; Patient Selection; Stereoisomerism; Vasodilator Agents | 2008 |
Thyrotoxicosis after parathyroidectomy mimicking myocardial infarction: a case report and review of the literature.
Topics: Benzazepines; Diagnosis, Differential; Female; Humans; Ivabradine; Middle Aged; Myocardial Infarction; Parathyroidectomy; Thyrotoxicosis; Treatment Outcome | 2012 |
11 trial(s) available for ivabradine and Cardiovascular Stroke
| Article | Year |
|---|---|
Risk following hospitalization in stable chronic systolic heart failure.
Topics: Aged; Aged, 80 and over; Benzazepines; Cardiovascular Agents; Chronic Disease; Disease Progression; Female; Follow-Up Studies; Heart Failure, Systolic; Hospitalization; Humans; Ivabradine; Male; Middle Aged; Myocardial Infarction; Prognosis; Risk Factors; Time Factors | 2013 |
[LINKOR: results of observational program in patients with myocardial infarction].
Topics: Adult; Aged; Aged, 80 and over; Benzazepines; Cyclic Nucleotide-Gated Cation Channels; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Heart Rate; Humans; Ivabradine; Male; Middle Aged; Myocardial Infarction; Quality of Life; Retrospective Studies; Russia; Treatment Outcome | 2013 |
Safety of intravenous ivabradine in acute ST-segment elevation myocardial infarction patients treated with primary percutaneous coronary intervention: a randomized, placebo-controlled, double-blind, pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Benzazepines; Double-Blind Method; Female; Heart Rate; Humans; Infusions, Intravenous; Ivabradine; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Pilot Projects; Tachycardia; Treatment Outcome | 2013 |
Use of ivabradine and atorvastatin in emergent orthopedic lower limb surgery and computed tomography coronary plaque imaging and novel biomarkers of cardiovascular stress and lipid metabolism for the study and prevention of perioperative myocardial infarc
Topics: Anti-Arrhythmia Agents; Atorvastatin; Benzazepines; Biomarkers; Clinical Protocols; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Emergencies; Femoral Neck Fractures; Heart Rate; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ivabradine; Middle Aged; Myocardial Infarction; Orthopedic Procedures; Plaque, Atherosclerotic; Predictive Value of Tests; Prospective Studies; Pyrroles; Research Design; Risk Factors; Severity of Illness Index; Tachycardia, Ventricular; Tomography, X-Ray Computed; Treatment Outcome; Victoria | 2014 |
Influence of Cardiovascular and Noncardiovascular Co-morbidities on Outcomes and Treatment Effect of Heart Rate Reduction With Ivabradine in Stable Heart Failure (from the SHIFT Trial).
Topics: Aged; Benzazepines; Cardiovascular Agents; Comorbidity; Cyclic Nucleotide-Gated Cation Channels; Double-Blind Method; Female; Follow-Up Studies; Global Health; Heart Failure, Systolic; Heart Rate; Humans; Incidence; Ivabradine; Male; Middle Aged; Myocardial Infarction; Pulmonary Disease, Chronic Obstructive; Survival Rate; Treatment Outcome | 2015 |
[Status of β-blocker use and heart rate control in Chinese patients with stable coronary artery disease].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Benzazepines; Blood Pressure; Coronary Angiography; Coronary Artery Disease; Electrocardiography; Female; Heart Failure; Heart Rate; Humans; Ivabradine; Male; Middle Aged; Myocardial Infarction; Outpatients; Percutaneous Coronary Intervention; Prospective Studies; Registries; Risk Factors | 2016 |
The BEAUTIFUL study: randomized trial of ivabradine in patients with stable coronary artery disease and left ventricular systolic dysfunction - baseline characteristics of the study population.
Topics: Aged; Benzazepines; Cardiovascular Agents; Coronary Artery Disease; Diabetes Complications; Double-Blind Method; Drug Therapy, Combination; Female; Heart Failure; Humans; Ivabradine; Male; Metabolic Syndrome; Middle Aged; Myocardial Infarction; Ventricular Dysfunction, Left | 2008 |
Randomised, double-blind, placebo-controlled trial of ivabradine in patients with acute coronary syndrome: effects of the If current inhibitor ivabradine on reduction of inflammation markers in patients with acute coronary syndrome--RIVIERA trial study de
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Benzazepines; Biomarkers; C-Reactive Protein; Double-Blind Method; Drug Administration Schedule; Endpoint Determination; Female; Heart Arrest; Humans; Inflammation; Ion Channels; Ivabradine; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Patient Admission | 2009 |
Relationship between ivabradine treatment and cardiovascular outcomes in patients with stable coronary artery disease and left ventricular systolic dysfunction with limiting angina: a subgroup analysis of the randomized, controlled BEAUTIFUL trial.
Topics: Adult; Angina Pectoris; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Coronary Artery Disease; Death, Sudden, Cardiac; Double-Blind Method; Female; Hospitalization; Humans; Ivabradine; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Ventricular Dysfunction, Left; Young Adult | 2009 |
Comparison of ivabradine versus metoprolol in early phases of reperfused anterior myocardial infarction with impaired left ventricular function: preliminary findings.
Topics: Aged; Benzazepines; Double-Blind Method; Female; Follow-Up Studies; Humans; Ivabradine; Male; Metoprolol; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Pilot Projects; Time Factors; Ventricular Dysfunction, Left | 2009 |
[Efficacy of ivabradin in combined treatment of patients with postinfarction systolic chronic cardiac failure].
Topics: Anti-Arrhythmia Agents; Benzazepines; Chronic Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Heart Failure, Systolic; Heart Rate; Humans; Ivabradine; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Treatment Outcome | 2011 |
43 other study(ies) available for ivabradine and Cardiovascular Stroke
| Article | Year |
|---|---|
Pharmacologic therapy for engraftment arrhythmia induced by transplantation of human cardiomyocytes.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cell Line; Cell- and Tissue-Based Therapy; Disease Models, Animal; Drug Combinations; Humans; Ivabradine; Male; Myocardial Infarction; Myocytes, Cardiac; Pluripotent Stem Cells; Stem Cell Transplantation; Swine; Tachycardia | 2021 |
Ivabradine is as effective as metoprolol in the prevention of ventricular arrhythmias in acute non-reperfused myocardial infarction in the rat.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Calcium Signaling; Cells, Cultured; Heart Rate; Ivabradine; Male; Metoprolol; Myocardial Infarction; Myocytes, Cardiac; Rats; Rats, Wistar; Ryanodine Receptor Calcium Release Channel; Tachycardia, Ventricular; Ventricular Fibrillation | 2020 |
Ivabradine improves survival and attenuates cardiac remodeling in isoproterenol-induced myocardial injury.
Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Heart Failure; Isoproterenol; Ivabradine; Male; Myocardial Infarction; Rats; Rats, Wistar; Ventricular Function, Left; Ventricular Remodeling | 2021 |
Heart Rate Reduction with Ivabradine Prevents Cardiac Rupture after Myocardial Infarction in Mice.
Topics: Animals; Heart Rate; Heart Rupture; Humans; Ivabradine; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Ventricular Remodeling | 2022 |
Ivabradine Induces Cardiac Protection against Myocardial Infarction by Preventing Cyclophilin-A Secretion in Pigs under Coronary Ischemia/Reperfusion.
Topics: Animals; Basigin; Biomarkers; Cardiotonic Agents; Cyclophilin A; Disease Models, Animal; Gene Expression Regulation; Heart; Humans; Ivabradine; Myocardial Infarction; Swine; Vesicle-Associated Membrane Protein 1 | 2021 |
Ivabradine protects rats against myocardial infarction through reinforcing autophagy via inhibiting PI3K/AKT/mTOR/p70S6K pathway.
Topics: Animals; Autophagy; Cardiotonic Agents; Cytokines; Diastole; Heart Ventricles; Hemodynamics; Inflammation Mediators; Ivabradine; Myocardial Infarction; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Systole; TOR Serine-Threonine Kinases | 2021 |
The efficacy of ivabradine in the treatment of acute myocardial infarction: A protocol for systematic review and meta-analysis.
Topics: Heart Rate; Humans; Ivabradine; Meta-Analysis as Topic; Myocardial Infarction; Rest; Stroke Volume; Systematic Reviews as Topic; Treatment Outcome; Ventricular Function, Left | 2021 |
Effects of Ivabradine on Heart Rate and Hemodynamic Parameters in a Swine Model of Cardiogenic Shock.
Topics: Animals; Arterial Pressure; Benzazepines; Blood Pressure; Cardiac Output; Central Venous Pressure; Female; Heart Rate; Hemodynamics; Ivabradine; Myocardial Infarction; Pulmonary Artery; Pulmonary Wedge Pressure; Shock, Cardiogenic; Swine; Tidal Volume | 2017 |
Mechano-chronotropic Unloading During the Acute Phase of Myocardial Infarction Markedly Reduces Infarct Size via the Suppression of Myocardial Oxygen Consumption.
Topics: Animals; Cardiovascular Agents; Combined Modality Therapy; Disease Models, Animal; Dogs; Heart Rate; Heart-Assist Devices; Ivabradine; Myocardial Infarction; Myocardium; Oxygen Consumption; Prosthesis Design; Prosthesis Implantation; Recovery of Function; Ventricular Function, Left | 2019 |
Ivabradine in acute heart failure: Effects on heart rate and hemodynamic parameters in a randomized and controlled swine trial.
Topics: Acute Disease; Animals; Arterial Pressure; Cardiac Output; Cardiovascular Agents; Disease Models, Animal; Female; Heart Failure; Heart Rate; Ivabradine; Myocardial Infarction; Sus scrofa; Time Factors | 2020 |
Ivabradine promotes angiogenesis and reduces cardiac hypertrophy in mice with myocardial infarction.
Topics: Administration, Oral; Angiogenesis Inducing Agents; Animals; Cardiomegaly; Cardiovascular Agents; Disease Models, Animal; Echocardiography; Electrocardiography; Heart Rate; Ivabradine; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Nitric Oxide Synthase Type III; Random Allocation | 2018 |
Effect of ivabradine on left ventricular remodelling after reperfused myocardial infarction: A pilot study.
Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Benzazepines; Drug Therapy, Combination; Feasibility Studies; Female; Heart Rate; Humans; Ivabradine; Magnetic Resonance Imaging; Male; Middle Aged; Myocardial Infarction; Myocardium; Percutaneous Coronary Intervention; Pilot Projects; Practice Guidelines as Topic; Time Factors; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling | 2014 |
Ivabradine protects against ventricular arrhythmias in acute myocardial infarction in the rat.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Calcium; Gene Expression Regulation; Ivabradine; Male; Myocardial Infarction; Potassium Channels; Rats; Rats, Inbred WKY | 2014 |
Effect of Chronic Heart Rate Reduction by I(f) Current Inhibitor Ivabradine on Left Ventricular Remodeling and Systolic Performance in Middle-Aged Rats With Postmyocardial Infarction Heart Failure.
Topics: Aging; Animals; Benzazepines; Collagen; Coronary Vessels; Cyclic Nucleotide-Gated Cation Channels; Heart Failure; Heart Rate; Ivabradine; Male; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Systole; Ventricular Function, Left; Ventricular Remodeling | 2015 |
Clinical trial results may lead to changes in cardiovascular care.
Topics: Aminobutyrates; Angioplasty; Angiotensin Receptor Antagonists; Benzazepines; Biphenyl Compounds; Clinical Trials as Topic; Drug Combinations; Heart Failure; Humans; Ivabradine; Myocardial Infarction; Practice Guidelines as Topic; Tetrazoles; Valsartan | 2014 |
[Clinical and Economic Efficacy of Ivabradine in Patients Suffered Myocardial Infarction].
Topics: Benzazepines; Cardiovascular Agents; Cost-Benefit Analysis; Costs and Cost Analysis; Cyclic Nucleotide-Gated Cation Channels; Drug Costs; Humans; Ivabradine; Myocardial Infarction; Retrospective Studies | 2015 |
Heart Rate Reduction With Ivabradine Protects Against Left Ventricular Remodeling by Attenuating Infarct Expansion and Preserving Remote-Zone Contractile Function and Synchrony in a Mouse Model of Reperfused Myocardial Infarction.
Topics: Animals; Benzazepines; Cardiovascular Agents; Disease Models, Animal; Echocardiography; Heart Rate; Heart Ventricles; Ivabradine; Magnetic Resonance Imaging, Cine; Male; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Ventricular Function, Left; Ventricular Remodeling | 2016 |
The Effects of Ivabradine on Cardiac Function after Myocardial Infarction are Weaker in Diabetic Rats.
Topics: Animals; Benzazepines; Cardiovascular Agents; Coronary Vessels; Diabetes Mellitus, Experimental; Disease Models, Animal; Echocardiography; Heart Failure; Heart Function Tests; Hyperglycemia; Ivabradine; Ligation; Male; Myocardial Infarction; Nerve Tissue Proteins; Norepinephrine; Rats; Rats, Sprague-Dawley; Signal Transduction; Streptozocin | 2016 |
[Causes of Angina Pectoris in Survivors of Myocardial Infarction and the Role of Optimization of Antianginal Therapy. Data of the LINKOR Study E..]
Topics: Aged; Angina Pectoris; Benzazepines; Cardiovascular Agents; Female; Humans; Ivabradine; Male; Middle Aged; Myocardial Infarction; Physical Exertion; Quality of Life; Risk Factors | 2016 |
[The role of beta-adrenoblockers and If-inhibitor ivabradine in lowering of rate of development of cardiac complications after carotid endarterectomy].
Topics: Adrenergic beta-Antagonists; Benzazepines; Carotid Artery Diseases; Drug Therapy, Combination; Endarterectomy, Carotid; Follow-Up Studies; Humans; Incidence; Ivabradine; Metoprolol; Middle Aged; Myocardial Infarction; Postoperative Complications; Retrospective Studies; Russia; Stereoisomerism; Treatment Outcome | 2008 |
Improvement of regional myocardial blood flow and function and reduction of infarct size with ivabradine: protection beyond heart rate reduction.
Topics: Animals; Benzazepines; Cardiovascular Agents; Coronary Circulation; Drug Evaluation, Preclinical; Heart Rate; Ivabradine; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Swine; Swine, Miniature | 2008 |
[Possibilities of the use of ivabradine in complex therapy acute coronary syndrome].
Topics: Aged; Benzazepines; Drug Therapy, Combination; Electrocardiography; Female; Fibrinolytic Agents; Follow-Up Studies; Heart Rate; Humans; Ivabradine; Male; Myocardial Infarction; Stereoisomerism; Thrombolytic Therapy | 2008 |
Pleiotropic action(s) of the bradycardic agent ivabradine: cardiovascular protection beyond heart rate reduction.
Topics: Animals; Atherosclerosis; Benzazepines; Cardiotonic Agents; Disease Models, Animal; Heart Rate; Humans; Ivabradine; Myocardial Infarction; Myocardial Reperfusion Injury; Ventricular Remodeling | 2008 |
Beneficial effects of delayed ivabradine treatment on cardiac anatomical and electrical remodeling in rat severe chronic heart failure.
Topics: Animals; Anti-Arrhythmia Agents; Benzazepines; Collagen; Disease Models, Animal; Drug Administration Schedule; Echocardiography, Doppler; Electrocardiography, Ambulatory; Fibrosis; Heart Failure; Heart Rate; Ivabradine; Male; Myocardial Infarction; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Severity of Illness Index; Stroke Volume; Telemetry; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Pressure; Ventricular Remodeling | 2009 |
Effects of ivabradine and metoprolol on cardiac angiogenesis and endothelial dysfunction in rats with heart failure.
Topics: Animals; Benzazepines; Heart Failure; Heart Rate; Ivabradine; Male; Metoprolol; Myocardial Infarction; Rats; Rats, Wistar; Ventricular Dysfunction, Left | 2009 |
Postmyocardial infarction remodeling and coronary reserve: effects of ivabradine and beta blockade therapy.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Atenolol; Benzazepines; Bradykinin; Cardiotonic Agents; Collagen; Coronary Circulation; Electrocardiography; Heart Rate; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Ivabradine; Male; Myocardial Infarction; Neovascularization, Physiologic; Organ Size; Perfusion; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Ventricular Remodeling | 2009 |
Chronic heart rate reduction with ivabradine improves systolic function of the reperfused heart through a dual mechanism involving a direct mechanical effect and a long-term increase in FKBP12/12.6 expression.
Topics: Animals; Anti-Arrhythmia Agents; Benzazepines; Blotting, Western; Calcium-Binding Proteins; Coronary Occlusion; Heart Rate; Ivabradine; Myocardial Infarction; Myocardial Reperfusion; Rabbits; Stroke Volume; Tacrolimus Binding Protein 1A; Ventricular Dysfunction, Left | 2010 |
Chronic heart rate reduction facilitates cardiomyocyte survival after myocardial infarction.
Topics: Animals; Anti-Arrhythmia Agents; Atenolol; Benzazepines; Bradycardia; Cell Survival; Cicatrix; Coronary Circulation; Diastole; Disease Models, Animal; Heart Rate; Ivabradine; Male; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Recovery of Function; Regeneration; Treatment Outcome | 2010 |
[Application of cardiac resynchronization therapy and ivabradine in a patient with chronic heart failure].
Topics: Benzazepines; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiovascular Agents; Digoxin; Diuretics; Echocardiography; Electrocardiography; Furosemide; Heart Atria; Heart Failure; Heart Rate; Heart Ventricles; Humans; Ivabradine; Male; Middle Aged; Myocardial Infarction; Spironolactone; Treatment Outcome | 2010 |
[Possibilities of if channels inhibitor ivabradine in complex treatment of survivors of myocardial infarction with stable angina].
Topics: Aged; Angina Pectoris; Benzazepines; Cyclic Nucleotide-Gated Cation Channels; Echocardiography; Follow-Up Studies; Humans; Ivabradine; Middle Aged; Myocardial Infarction; Time Factors; Tomography, Emission-Computed; Tomography, X-Ray Computed; Treatment Outcome | 2010 |
Heart rate reduction with ivabradine prevents the global phenotype of left ventricular remodeling.
Topics: Action Potentials; Animals; Benzazepines; Electrocardiography; Energy Metabolism; Heart; Heart Rate; Ivabradine; Male; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; Ventricular Function, Left; Ventricular Remodeling | 2011 |
Clinical trials update from the European Society of Cardiology Meeting 2010: SHIFT, PEARL-HF, STAR-heart, and HEBE-III.
Topics: Adrenergic beta-Antagonists; Benzazepines; Clinical Trials as Topic; Comorbidity; Cyclic Nucleotide-Gated Cation Channels; Drug Therapy, Combination; Erythropoietin; Heart Failure; Hematinics; Humans; Hyperkalemia; Ivabradine; Myocardial Infarction; Polymers; Renal Insufficiency; Stem Cell Transplantation | 2010 |
[Antianginal efficacy of ivabradine in a very old patient with aortic stenosis: effects on cardiac output and transvalvular aortic gradients].
Topics: Adrenergic beta-Antagonists; Aged, 80 and over; Angina Pectoris; Aortic Valve Stenosis; Benzazepines; Cardiotonic Agents; Drug Therapy, Combination; Humans; Ivabradine; Male; Myocardial Infarction | 2010 |
Long-term treatment with ivabradine in post-myocardial infarcted rats counteracts f-channel overexpression.
Topics: Animals; Benzazepines; Cyclic Nucleotide-Gated Cation Channels; Heart Atria; Heart Rate; Heart Ventricles; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channels; Ivabradine; Male; MicroRNAs; Myocardial Infarction; Myocytes, Cardiac; Potassium Channels; Rats; Rats, Wistar; Ventricular Remodeling | 2012 |
Heart rate reduction induced by the if current inhibitor ivabradine improves diastolic function and attenuates cardiac tissue hypoxia.
Topics: Animals; Benzazepines; Cell Hypoxia; Cell Proliferation; Diastole; Disease Models, Animal; Heart Failure; Heart Rate; Hypoxia-Inducible Factor 1, alpha Subunit; Ivabradine; Male; Myocardial Infarction; Nitric Oxide; Rats; Rats, Wistar; Time Factors; Vasodilation; Ventricular Dysfunction, Left; Ventricular Function, Left | 2012 |
[Update coronary artery disease: important progresses in acute and chronic therapy].
Topics: Acetanilides; Angina Pectoris; Angioplasty, Balloon, Coronary; Benzazepines; Coronary Artery Disease; Early Medical Intervention; Humans; Ivabradine; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Ranolazine; Survival Rate; Thrombolytic Therapy | 2012 |
Long-term heart rate reduction induced by the selective I(f) current inhibitor ivabradine improves left ventricular function and intrinsic myocardial structure in congestive heart failure.
Topics: Animals; Benzazepines; Capillaries; Cardiac Output; Collagen; Drug Evaluation, Preclinical; Heart Failure; Heart Rate; Heart Ventricles; Ion Transport; Ivabradine; Male; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; Sinoatrial Node; Stroke Volume; Ventricular Function, Left; Ventricular Remodeling | 2004 |
[Ivabradine -- a novel approach for heart rate lowering].
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Angina Pectoris; Animals; Benzazepines; Contraindications; Electrocardiography; Heart Failure; Heart Rate; Humans; Ivabradine; Myocardial Infarction; Randomized Controlled Trials as Topic; Sinoatrial Node; Treatment Outcome; Ventricular Function, Left | 2005 |
[Possibilities of reducing heart rate by I(f)-channel inhibitors].
Topics: Angina Pectoris; Anti-Arrhythmia Agents; Benzazepines; Cause of Death; Cyclic Nucleotide-Gated Cation Channels; Electrocardiography; Exercise Test; Heart Rate; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channels; Ivabradine; Muscle Proteins; Myocardial Infarction; Potassium Channels; Prognosis; Randomized Controlled Trials as Topic; Sinoatrial Node; Stereoisomerism; Tachycardia | 2006 |
Comparison of a beta-blocker and an If current inhibitor in rabbits with myocardial infarction.
Topics: Adrenergic beta-Antagonists; Animals; Aorta; Benzazepines; Blood Flow Velocity; Cardiotonic Agents; Coronary Circulation; Disease Models, Animal; Electrocardiography; Heart Rate; Heart Ventricles; Ivabradine; Male; Metoprolol; Myocardial Contraction; Myocardial Infarction; Natriuretic Peptide, Brain; Oxygen Consumption; Potassium Channel Blockers; Rabbits; Time Factors; Ventricular Function, Left; Ventricular Myosins | 2006 |
Rationale and design of a randomized, double-blind, placebo-controlled trial of ivabradine in patients with stable coronary artery disease and left ventricular systolic dysfunction: the morBidity-mortality EvAlUaTion of the I(f) inhibitor ivabradine in pa
Topics: Adult; Benzazepines; Cardiovascular Agents; Coronary Artery Disease; Double-Blind Method; Female; Heart Rate; Hospitalization; Humans; Ivabradine; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Randomized Controlled Trials as Topic; Research Design; Ventricular Dysfunction, Left | 2006 |
Preservation of coronary reserve by ivabradine-induced reduction in heart rate in infarcted rats is associated with decrease in perivascular collagen.
Topics: Animals; Benzazepines; Collagen; Coronary Circulation; Coronary Vessels; Fractional Flow Reserve, Myocardial; Heart Rate; Ivabradine; Male; Myocardial Infarction; Rats; Rats, Sprague-Dawley | 2007 |
Effect of metoprolol and ivabradine on left ventricular remodelling and Ca2+ handling in the post-infarction rat heart.
Topics: Adrenergic beta-Antagonists; Animals; Benzazepines; Calcium; Disease Models, Animal; Heart Failure; Heart Rate; Hypertrophy, Left Ventricular; Ivabradine; Male; Metoprolol; Myocardial Infarction; Rats; Rats, Wistar; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sodium-Calcium Exchanger; Ventricular Remodeling | 2008 |