Page last updated: 2024-09-04

ivabradine and Cardiovascular Diseases

ivabradine has been researched along with Cardiovascular Diseases in 42 studies

Research

Studies (42)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	14 (33.33)	29.6817
2010's	24 (57.14)	24.3611
2020's	4 (9.52)	2.80

Authors

Authors	Studies
D'Orazio, N; Gammone, MA; Massari, F; Riccioni, G	1
Barhdadi, A; de Denus, S; Dubé, MP; Legault, MA; Lemieux Perreault, LP; Lumbers, RT; Provost, S; Sandoval, J; Shah, S; Tardif, JC; Tyl, B	1
Benstoem, C; Brandenburg, V; Breuer, T; Heussen, N; Kalvelage, C; Marx, G; Stoppe, C	1
Bangalore, S; Chen, C; Godoy, LC; Kaur, G; Mehta, PK; Morrone, D; Sidhu, MS	1
Dukkipati, SR; Koruth, JS; Lala, A; Pinney, S; Reddy, VY	1
Kang, S; Li, CJ; Zhang, XM	1
Dvorianchikova, ZY; Gatsura, SV; Golosova, AN; Karamysheva, EI; Ulyanova, EA	1
Newale, S; Sathyamurthy, I	1
Higo, T; Ide, T; Kawasaki, Y; Ohtani, K; Tanaka, M; Tsutsui, H	1
Bangalore, S; Messerli, FH; Tanna, MS	1
Böhm, M; Custodis, F; Laufs, U; Reil, JC	1
Bemelmans, RH; Visseren, FL	1
Adam, O; Böhm, M; Custodis, F; Laufs, U; Möhlenkamp, S; Reil, JC; Schirmer, SH	1
Ferrari, R; Ford, I; Fox, K; Steg, PG; Tardif, JC; Tendera, M	1
Dulsat, C	1
Böhm, M; Borer, JS; Deedwania, P; Kim, JB; Reil, JC	1
Angelini, L; Battistoni, I; Perna, GP	1
Armenian, SH; Ehrhardt, MJ; Fulbright, JM	1
Nguyen, E; Weeda, ER; White, CM	1
Böhm, M; Borer, JS; Ewen, S; Ford, I; Komajda, M; Laufs, U; Lloyd, SM; Lopez-Sendon, J; Mahfoud, F; Ponikowski, P; Swedberg, K; Tavazzi, L	1
Bolorunduro, OB; Jha, SK; Oliphant, CS; Owens, RE	1
Champion, S	1
Tardif, JC	1
Ferrari, R; Ford, I; Fox, K; Robertson, M; Steg, PG; Tendera, M	1
Thorin, E; Thorin-Trescases, N	1
Bruguera Cortada, J; Varela, A	1
Riccioni, G	1
Ceconi, C; Ferrari, R	1
Bonadei, I; Bontempi, L; Curnis, A; D'Aloia, A; Dei Cas, L; Del Magro, F; Piovanelli, B; Vizzardi, E	1
Franceschelli, S; Riccioni, G; Speranza, L	1
De Santis, V; Magliocca, A; Nencini, C; Porto, AG; Santoro, A; Tritapepe, L; Vitale, D	1
Crea, F; Di Franco, A; Ghirlanda, G; Lanza, GA; Milo, M; Nerla, R; Pitocco, D; Russo, G; Sarullo, FM; Stazi, A; Tarzia, P; Villano, A; Zaccardi, F	1
Mangoni, ME; Marger, L; Nargeot, J	1
Danchin, N; Kadri, Z	1
Cargnoni, A; Ceconi, C; Ferrari, R; Stavroula, G	1
Camm, AJ; Savelieva, I	1
Tendera, M	1
Dilaveris, P; Gatzoulis, K; Giannopoulos, G; Stefanadis, C; Synetos, A	1
Mach, F; Purcell, H	1
Borer, JS	1
Böhm, M; Reil, JC	1
Triggle, CR	1

Reviews

31 review(s) available for ivabradine and Cardiovascular Diseases

Article	Year
Beneficial effect of ivabradine against cardiovascular diseases. Frontiers in bioscience (Scholar edition), 2020, 03-01, Volume: 12, Issue:1 Topics: Animals; Cardiovascular Agents; Cardiovascular Diseases; Heart Rate; Humans; Ivabradine; Randomized Controlled Trials as Topic	2020
Ivabradine as adjuvant treatment for chronic heart failure. The Cochrane database of systematic reviews, 2020, 11-04, Volume: 11 Topics: Bias; Cardiovascular Agents; Cardiovascular Diseases; Chemotherapy, Adjuvant; Chronic Disease; Exercise Tolerance; Female; Heart Failure; Humans; Ivabradine; Male; Middle Aged; Placebos; Randomized Controlled Trials as Topic; Stroke Volume	2020
Ivabradine in Cardiovascular Disease Management Revisited: a Review. Cardiovascular drugs and therapy, 2021, Volume: 35, Issue:5 Topics: Cardiovascular Agents; Cardiovascular Diseases; Humans; Ivabradine; Myocardial Ischemia; Prospective Studies; Randomized Controlled Trials as Topic; Stroke Volume; Tachycardia, Sinus	2021
The Clinical Use of Ivabradine. Journal of the American College of Cardiology, 2017, Oct-03, Volume: 70, Issue:14 Topics: Benzazepines; Cardiovascular Agents; Cardiovascular Diseases; Cyclic Nucleotide-Gated Cation Channels; Heart Rate; Humans; Ivabradine	2017
Ivabradine has a neutral effect on mortality in randomized controlled trials. Medicine, 2017, Volume: 96, Issue:40 Topics: Adrenergic beta-Antagonists; Aged; Benzazepines; Cardiovascular Agents; Cardiovascular Diseases; Cause of Death; Female; Heart Rate; Humans; Ivabradine; Male; Middle Aged; Odds Ratio; Randomized Controlled Trials as Topic; Rest; Risk Factors; Treatment Outcome	2017
Ivabradine: Evidence and current role in cardiovascular diseases and other emerging indications. Indian heart journal, 2018, Volume: 70 Suppl 3 Topics: Cardiovascular Agents; Cardiovascular Diseases; Cause of Death; Global Health; Humans; Ivabradine; Survival Rate	2018
Ivabradine for the Treatment of Cardiovascular Diseases. Circulation journal : official journal of the Japanese Circulation Society, 2019, 01-25, Volume: 83, Issue:2 Topics: Cardiovascular Diseases; Heart Rate; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ivabradine; Sinoatrial Node	2019
Stable coronary artery disease: are there therapeutic benefits of heart rate lowering? Journal of hypertension, 2019, Volume: 37, Issue:6 Topics: Adrenergic beta-Antagonists; Cardiovascular Diseases; Coronary Artery Disease; Heart; Heart Rate; Humans; Ivabradine	2019
[The resting heart rate]. Nederlands tijdschrift voor geneeskunde, 2014, Volume: 158 Topics: Benzazepines; Blood Pressure; Cardiovascular Diseases; Heart Failure; Heart Rate; Humans; Ivabradine; Prognosis; Risk Factors; Tachycardia	2014
[Heart rate: clinical variable and risk marker]. Deutsche medizinische Wochenschrift (1946), 2014, Volume: 139, Issue:33 Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Cardiomyopathy, Dilated; Cardiovascular Diseases; Dose-Response Relationship, Drug; Drug Therapy, Combination; Heart Rate; Humans; Ivabradine; Male; Mineralocorticoid Receptor Antagonists; Reference Values; Risk Factors; Survival Rate; Ventricular Dysfunction, Left	2014
Resting heart rate: risk indicator and emerging risk factor in cardiovascular disease. The American journal of medicine, 2015, Volume: 128, Issue:3 Topics: Benzazepines; Cardiovascular Agents; Cardiovascular Diseases; Heart Rate; Humans; Ivabradine; Rest; Risk Factors; Treatment Outcome	2015
[Heart rate modulation in stable ischemic heart disease: what we have learned from the SIGNIFY study?]. Giornale italiano di cardiologia (2006), 2015, Volume: 16, Issue:3 Topics: Benzazepines; Cardiovascular Diseases; Clinical Trials as Topic; Coronary Artery Disease; Drug Interactions; Heart Rate; Humans; Ivabradine; Myocardial Ischemia; Risk Factors; Treatment Outcome	2015
Role of Ivabradine in the Treatment of Patients With Cardiovascular Disease. The Annals of pharmacotherapy, 2016, Volume: 50, Issue:6 Topics: Angina Pectoris; Benzazepines; Canada; Cardiovascular Diseases; Coronary Artery Disease; Female; Heart Failure, Systolic; Heart Rate; Humans; Ivabradine; Male; Myocardial Infarction; Stroke Volume; Treatment Outcome	2016
Ivabradine: A Review of Labeled and Off-Label Uses. American journal of cardiovascular drugs : drugs, devices, and other interventions, 2016, Volume: 16, Issue:5 Topics: Adrenergic beta-Antagonists; Benzazepines; Blood Pressure; Cardiovascular Agents; Cardiovascular Diseases; Clinical Trials as Topic; Heart Rate; Humans; Ivabradine; Off-Label Use	2016
Comment on: Ivabradine: A Review of Labeled and Off-Label Uses. American journal of cardiovascular drugs : drugs, devices, and other interventions, 2016, Volume: 16, Issue:6 Topics: Benzazepines; Cardiovascular Agents; Cardiovascular Diseases; Drug Utilization; Humans; Ivabradine; Off-Label Use	2016
Ivabradine: I(f) inhibition in the management of stable angina pectoris and other cardiovascular diseases. Drugs of today (Barcelona, Spain : 1998), 2008, Volume: 44, Issue:3 Topics: Angina Pectoris; Animals; Benzazepines; Cardiotonic Agents; Cardiovascular Diseases; Heart Rate; Humans; Ivabradine	2008
Vascular endothelial ageing, heartbeat after heartbeat. Cardiovascular research, 2009, Oct-01, Volume: 84, Issue:1 Topics: Adrenergic beta-Antagonists; Aging; Animals; Atherosclerosis; Baroreflex; Benzazepines; Cardiovascular Diseases; Endothelium, Vascular; Heart Rate; Humans; Ivabradine; Nitric Oxide; Pulsatile Flow; Risk Factors; Shear Strength; Stress, Mechanical	2009
Role of heart rate in cardiovascular diseases: how the results of the BEAUTIFUL study change clinical practice. American journal of cardiovascular drugs : drugs, devices, and other interventions, 2009, Volume: 9 Suppl 1 Topics: Aged; Benzazepines; Cardiovascular Diseases; Coronary Artery Disease; Female; Heart Rate; Humans; Ivabradine; Male; Middle Aged; Randomized Controlled Trials as Topic; Ventricular Dysfunction, Left	2009
Ivabradine: recent and potential applications in clinical practice. Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:3 Topics: Angina Pectoris; Animals; Benzazepines; Cardiovascular Agents; Cardiovascular Diseases; Coronary Artery Disease; Female; Heart Rate; Humans; Ivabradine; Male; Risk Factors; Ventricular Dysfunction, Left	2011
Selective and specific I(f) inhibition with ivabradine: new perspectives for the treatment of cardiovascular disease. Expert review of cardiovascular therapy, 2011, Volume: 9, Issue:8 Topics: Animals; Benzazepines; Cardiotonic Agents; Cardiovascular Diseases; Cyclic Nucleotide-Gated Cation Channels; Depression, Chemical; Drug Interactions; Heart Rate; Humans; Ivabradine; Myocardial Contraction; Ventricular Function, Left	2011
The importance of reducing heart rate in cardiovascular diseases: effects of Ivabradine. Minerva medica, 2011, Volume: 102, Issue:5 Topics: Adrenergic beta-Antagonists; Angina Pectoris; Benzazepines; Cardiovascular Agents; Cardiovascular Diseases; Clinical Trials as Topic; Cyclic Nucleotide-Gated Cation Channels; Heart Failure; Heart Rate; Humans; Ivabradine; Myocardial Ischemia; Prognosis; Sinoatrial Node	2011
The biological effects of ivabradine in cardiovascular disease. Molecules (Basel, Switzerland), 2012, Apr-30, Volume: 17, Issue:5 Topics: Animals; Benzazepines; Cardiovascular Diseases; CD4-Positive T-Lymphocytes; Cell Movement; Chemokine CCL2; Cyclic Nucleotide-Gated Cation Channels; Gene Expression; Heart Rate; Humans; Ivabradine; NADPH Oxidases; Risk Factors; Sinoatrial Node	2012
Ivabradine: potential clinical applications in critically ill patients. Clinical research in cardiology : official journal of the German Cardiac Society, 2013, Volume: 102, Issue:3 Topics: Anti-Arrhythmia Agents; Benzazepines; Cardiac Surgical Procedures; Cardiotonic Agents; Cardiovascular Diseases; Critical Illness; Drug Interactions; Heart; Heart Rate; Humans; Ivabradine; Myocardial Contraction; Sympathetic Nervous System; Treatment Outcome; Ventricular Function	2013
If current inhibition: cellular basis and physiology. Advances in cardiology, 2006, Volume: 43 Topics: Animals; Benzazepines; Cardiotonic Agents; Cardiovascular Diseases; Diastole; Heart Conduction System; Heart Rate; Humans; Ion Channels; Ivabradine	2006
Clinical perspectives of heart rate slowing for coronary event reduction and heart failure. Advances in cardiology, 2006, Volume: 43 Topics: Adrenergic beta-Antagonists; Benzazepines; Cardiotonic Agents; Cardiovascular Diseases; Diastole; Heart Conduction System; Heart Rate; Humans; Ion Channels; Ivabradine; Oxygen Consumption	2006
Heart rate reduction by pharmacological If current inhibition. Advances in cardiology, 2006, Volume: 43 Topics: Benzazepines; Cardiotonic Agents; Cardiovascular Diseases; Diastole; Heart Conduction System; Heart Rate; Humans; Ion Channels; Ivabradine; Myocardial Contraction	2006
Novel If current inhibitor ivabradine: safety considerations. Advances in cardiology, 2006, Volume: 43 Topics: Adrenergic beta-Antagonists; Angina Pectoris; Automobile Driving; Benzazepines; Bradycardia; Cardiotonic Agents; Cardiovascular Diseases; Clinical Trials as Topic; Eye; Heart Conduction System; Heart Rate; Humans; Ion Channels; Ivabradine; Sinoatrial Node	2006
Future directions: what data do we need? Advances in cardiology, 2006, Volume: 43 Topics: Adrenergic beta-Antagonists; Benzazepines; Cardiotonic Agents; Cardiovascular Diseases; Clinical Trials as Topic; Diastole; Heart Conduction System; Heart Rate; Humans; Ion Channels; Ivabradine	2006
Heart rate lowering by inhibition of the pacemaker current: a new therapeutic perspective in cardiovascular disease. Cardiovascular & hematological agents in medicinal chemistry, 2006, Volume: 4, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Benzazepines; Cardiovascular Diseases; Clinical Trials as Topic; Dose-Response Relationship, Drug; Heart Rate; Humans; Ion Channels; Ivabradine; Sinoatrial Node; Tachycardia, Sinus	2006
[Heart rate as a cardiovascular risk factor: potential clinical benefit with ivabradine]. Revue medicale suisse, 2007, May-30, Volume: 3, Issue:113 Topics: Benzazepines; Cardiovascular Diseases; Heart Rate; Humans; Ivabradine; Risk Factors	2007
Perspectives of I(f) inhibition by ivabradine in cardiology. Drugs, 2007, Volume: 67 Suppl 2 Topics: Benzazepines; Cardiovascular Diseases; Heart Rate; Humans; Ion Channels; Ivabradine	2007

Trials

3 trial(s) available for ivabradine and Cardiovascular Diseases

Article	Year
Ivabradine in stable coronary artery disease without clinical heart failure. The New England journal of medicine, 2014, Sep-18, Volume: 371, Issue:12 Topics: Adrenergic beta-Antagonists; Aged; Angina, Stable; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Cardiovascular Diseases; Coronary Artery Disease; Double-Blind Method; Drug Therapy, Combination; Female; Heart Failure; Heart Rate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intention to Treat Analysis; Ivabradine; Kaplan-Meier Estimate; Male; Middle Aged; Risk	2014
Heart rate as a prognostic risk factor in patients with coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a subgroup analysis of a randomised controlled trial. Lancet (London, England), 2008, Sep-06, Volume: 372, Issue:9641 Topics: Aged; Benzazepines; Cardiovascular Diseases; Coronary Disease; Female; Heart Rate; Humans; Ivabradine; Male; Middle Aged; Prognosis; Proportional Hazards Models; Risk Factors; Tachycardia; Ventricular Dysfunction, Left	2008
Differential effects of heart rate reduction by atenolol or ivabradine on peripheral endothelial function in type 2 diabetic patients. Heart (British Cardiac Society), 2012, Volume: 98, Issue:24 Topics: Atenolol; Benzazepines; Brachial Artery; Cardiovascular Diseases; Cyclic Nucleotide-Gated Cation Channels; Diabetes Mellitus, Type 2; Double-Blind Method; Electrocardiography; Endothelium, Vascular; Female; Follow-Up Studies; Heart Rate; Humans; Ivabradine; Male; Middle Aged; Prospective Studies; Sympathetic Nervous System; Sympatholytics; Vasodilation	2012

Other Studies

8 other study(ies) available for ivabradine and Cardiovascular Diseases

Article	Year
A genetic model of ivabradine recapitulates results from randomized clinical trials. PloS one, 2020, Volume: 15, Issue:7 Topics: Adult; Aged; Alleles; Cardiovascular Diseases; Endpoint Determination; Female; Genetic Variation; Genome-Wide Association Study; Heart Rate; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ivabradine; Male; Mendelian Randomization Analysis; Middle Aged; Models, Genetic; Muscle Proteins; Potassium Channels; Randomized Controlled Trials as Topic; Risk Factors	2020
[Ivabradine in Modern Pharmacotherapy of Cardiovascular Diseases - Realities and Prospects]. Kardiologiia, 2018, Issue:2 Topics: Benzazepines; Cardiovascular Agents; Cardiovascular Diseases; Heart Rate; Humans; Ivabradine	2018
Heart rate: a global target for cardiovascular disease and therapy along the cardiovascular disease continuum. Journal of cardiology, 2013, Volume: 62, Issue:3 Topics: Atherosclerosis; Benzazepines; Cardiovascular Diseases; Endothelium, Vascular; Heart Rate; Humans; Ivabradine; Prognosis; Rest; Risk; Risk Factors; Stroke	2013
A report from the European Society of Cardiology Congress 2014 (August 30-September 3 - Barcelona, Spain). Drugs of today (Barcelona, Spain : 1998), 2014, Volume: 50, Issue:9 Topics: Aminobutyrates; Benzaldehydes; Benzazepines; Biphenyl Compounds; Cardiology; Cardiovascular Diseases; Drug Combinations; Enalapril; Humans; Ivabradine; Oximes; Stents; Tetrazoles; Valsartan	2014
Screening and intervention for treatment-related cardiac dysfunction in childhood cancer survivors. Future oncology (London, England), 2015, Volume: 11, Issue:14 Topics: Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Biomarkers; Cardiovascular Diseases; Child; Echocardiography; Guidelines as Topic; Humans; Ivabradine; Neoplasms; Survivors; Troponin I; Troponin T	2015
Non-adherence to ivabradine and placebo and outcomes in chronic heart failure: an analysis from SHIFT. European journal of heart failure, 2016, Volume: 18, Issue:6 Topics: Aged; Benzazepines; Cardiovascular Agents; Cardiovascular Diseases; Cause of Death; Double-Blind Method; Female; Heart Failure; Heart Failure, Systolic; Hospitalization; Humans; Ivabradine; Male; Medication Adherence; Middle Aged; Mortality; Placebos; Proportional Hazards Models; Randomized Controlled Trials as Topic	2016
If inhibition by Ivabradine. Foreword. Drugs, 2007, Volume: 67 Suppl 2 Topics: Benzazepines; Cardiovascular Diseases; Heart Rate; Humans; Ivabradine	2007
Defying the economists: a decrease in heart rate improves not only cardiac but also endothelial function. British journal of pharmacology, 2008, Volume: 154, Issue:4 Topics: Animals; Benzazepines; Cardiotonic Agents; Cardiovascular Diseases; Endothelium, Vascular; Heart Rate; Humans; Ivabradine; Mice; Sinoatrial Node; Vasodilation	2008