Page last updated: 2024-09-04

ivabradine and Cardiac Remodeling, Ventricular

ivabradine has been researched along with Cardiac Remodeling, Ventricular in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (21.88)29.6817
2010's20 (62.50)24.3611
2020's5 (15.63)2.80

Authors

AuthorsStudies
Che Hassan, HH; Kamisah, Y1
Adamcova, M; Aziriova, S; Baka, T; Krajcirovicova, K; Paulis, L; Repova, K; Simko, F1
Chen, H; Guo, R; Liu, Q; Luo, X; Xu, Y; Yan, S; Zhang, W; Zhong, X1
Abe, K; Furusawa, S; Ide, T; Ikeda, M; Ikeda, S; Ishikita, A; Ishimaru, K; Matsushima, S; Miyamoto, HD; Okabe, K; Tadokoro, T; Tsutsui, H1
Kruszewski, M; Leszek, P; Mackiewicz, U; Mączewski, M; Oknińska, M; Paterek, A; Śmigielski, W; Sochanowicz, B1
Bruckner, T; Darche, FF; Doesch, AO; Ehlermann, P; Helmschrott, M; Katus, HA; Rahm, AK; Rivinius, R; Ruhparwar, A; Thomas, D1
Bonadei, I; Carubelli, V; Fabbricatore, D; Lombardi, CM; Metra, M; Pagnoni, M; Rossi, L; Sciatti, E; Vizzardi, E1
Dengler, T; Doesch, AO; Ehlermann, P; Erbel, C; Frankenstein, L; Gleissner, CA; Hardt, S; Katus, HA; Mueller, S; Ruhparwar, A1
Bonnet, J; Chasseriaud, W; Cochet, H; Coste, P; Douard, H; Gerbaud, E; Gilbert, S; Horovitz, A; Montaudon, M; Pucheu, Y1
Bogatyryov, Y; Christensen, LP; Dedkov, EI; McCooey, DS; Tomanek, RJ; Weiss, RM1
Berdeaux, A; Bizé, A; Ghaleh, B; Hittinger, L; Jozwiak, M; Melka, J; Rienzo, M; Sambin, L; Su, JB1
Pereira-Barretto, AC1
Borer, JS; Tavazzi, L1
Beyers, RJ; French, BA; Hossack, JA; Lin, D; O'Connor, DM; Piras, BA; Smith, RS1
Heusch, G1
Delcayre, C; Messaoudi, S; Milliez, P; Nehme, J; Rodriguez, C; Samuel, JL1
Campanelli, JJ; Christensen, LP; Dedkov, EI; Tomanek, RJ; Weiss, RM; Zhang, RL; Zheng, W1
Riccioni, G1
Bouly, M; Ceconi, C; Cerbai, E; Comini, L; Ferrari, R; Mugelli, A; Stillitano, F; Suffredini, S1
Ceconi, C; Ferrari, R; Ford, I; Fox, K; Freedman, SB; Gueret, P; Hildebrandt, P; McDonagh, T; Parrinello, G; Robertson, M; Steg, PG; Tardif, JC; Tendera, M1
Bouly, M; Brogioni, S; Ceconi, C; Cerbai, E; Comini, L; Ferrari, R; Mugelli, A; Stillitano, F; Suffredini, S1
Fruhwald, F; Pieske, B1
Böhm, M; Borer, JS; Ford, I; Komajda, M; O'Meara, E; Swedberg, K; Tardif, JC; Tavazzi, L1
Albajrami, O; Bellumkonda, L; Jacoby, D1
Becher, PM; Lindner, D; Miteva, K; Savvatis, K; Schmack, B; Schultheiss, HP; Tschöpe, C; Van Linthout, S; Westermann, D; Zietsch, C1
Dias, P; Gandhi, A; Ibrahim, M; Navaratnarajah, M; Sarathchandra, P; Shah, A; Siedlecka, U; Terracciano, CM; van Doorn, C; Yacoub, MH1
Málek, F1
Cho, KI; Han, J; Kim, BH; Kim, IJ; Kim, JY; Kim, N; Kim, SM1
Barbier, S; Chagraoui, A; Henry, JP; Lallemand, F; Lerebours, G; Mahlberg-Gaudin, F; Mulder, P; Renet, S; Richard, V; Thuillez, C1
Bedossa, P; Ciobotaru, V; Escoubet, B; Heimburger, M; Heymes, C; Logeart, D; Louedec, L; Mercadier, JJ; Michel, JB; Ventura-Clapier, R1
Berdeaux, A1
Mackiewicz, U; Maczewski, M1

Reviews

5 review(s) available for ivabradine and Cardiac Remodeling, Ventricular

ArticleYear
Therapeutic Use and Molecular Aspects of Ivabradine in Cardiac Remodeling: A Review.
    International journal of molecular sciences, 2023, Feb-01, Volume: 24, Issue:3

    Topics: Animals; Benzazepines; Heart Failure; Heart Rate; Ivabradine; Quality of Life; Ventricular Remodeling

2023
Cardiac and Hemodynamic Benefits: Mode of Action of Ivabradine in Heart Failure.
    Advances in therapy, 2015, Volume: 32, Issue:10

    Topics: Benzazepines; Cardiovascular Agents; Heart Failure; Heart Rate; Hemodynamics; Humans; Ivabradine; Stroke Volume; Ventricular Remodeling

2015
Update on ivabradine for heart failure.
    Trends in cardiovascular medicine, 2016, Volume: 26, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Benzazepines; Cyclic Nucleotide-Gated Cation Channels; Heart Failure; Heart Rate; Humans; Ivabradine; Quality of Life; Signal Transduction; Sinoatrial Node; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling

2016
Ivabradine: from molecular basis to clinical effectiveness.
    Advances in therapy, 2010, Volume: 27, Issue:3

    Topics: Benzazepines; Cardiovascular Agents; Coronary Artery Disease; Diabetes Complications; Heart Rate; Humans; Ivabradine; Sinoatrial Node; Ventricular Remodeling

2010
Preclinical results with I(f) current inhibition by ivabradine.
    Drugs, 2007, Volume: 67 Suppl 2

    Topics: Animals; Benzazepines; Cardiac Output; Coronary Circulation; Cyclic Nucleotide-Gated Cation Channels; Drug Evaluation, Preclinical; Heart Conduction System; Heart Rate; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ivabradine; Mice; Muscle Proteins; Myocardial Contraction; Myocardial Ischemia; Myocardium; Potassium Channels; Rats; Stroke Volume; Ventricular Function, Left; Ventricular Remodeling

2007

Trials

2 trial(s) available for ivabradine and Cardiac Remodeling, Ventricular

ArticleYear
Effect of heart rate reduction by ivabradine on left ventricular remodeling in the echocardiographic substudy of BEAUTIFUL.
    International journal of cardiology, 2011, Feb-03, Volume: 146, Issue:3

    Topics: Aged; Benzazepines; Coronary Occlusion; Double-Blind Method; Female; Heart Rate; Humans; Ivabradine; Male; Ultrasonography; Ventricular Remodeling

2011
Effects of selective heart rate reduction with ivabradine on left ventricular remodelling and function: results from the SHIFT echocardiography substudy.
    European heart journal, 2011, Volume: 32, Issue:20

    Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Double-Blind Method; Echocardiography; Female; Heart Failure; Humans; Ivabradine; Male; Middle Aged; Stroke Volume; Ventricular Dysfunction, Left; Ventricular Remodeling

2011

Other Studies

25 other study(ies) available for ivabradine and Cardiac Remodeling, Ventricular

ArticleYear
Ivabradine improves survival and attenuates cardiac remodeling in isoproterenol-induced myocardial injury.
    Fundamental & clinical pharmacology, 2021, Volume: 35, Issue:4

    Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Heart Failure; Isoproterenol; Ivabradine; Male; Myocardial Infarction; Rats; Rats, Wistar; Ventricular Function, Left; Ventricular Remodeling

2021
Effect of early use of ivabradine on left ventricular remodeling after primary percutaneous coronary intervention in patients with acute ST-segment elevation myocardial infarction: A pilot test.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2021, Volume: 26, Issue:2

    Topics: Acute Disease; Cardiovascular Agents; Female; Humans; Ivabradine; Male; Middle Aged; Percutaneous Coronary Intervention; Pilot Projects; ST Elevation Myocardial Infarction; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling

2021
Heart Rate Reduction with Ivabradine Prevents Cardiac Rupture after Myocardial Infarction in Mice.
    Cardiovascular drugs and therapy, 2022, Volume: 36, Issue:2

    Topics: Animals; Heart Rate; Heart Rupture; Humans; Ivabradine; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Ventricular Remodeling

2022
Ivabradine prevents deleterious effects of dopamine therapy in heart failure: No role for HCN4 overexpression.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 136

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dopamine; Female; Heart Failure; Heart Rate; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ivabradine; Male; Muscle Proteins; Myocardium; Potassium Channels; Rats, Wistar; Ventricular Function, Left; Ventricular Remodeling

2021
Control of cardiac chronotropic function in patients after heart transplantation: effects of ivabradine and metoprolol succinate on resting heart rate in the denervated heart.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2018, Volume: 107, Issue:2

    Topics: Adult; Anti-Arrhythmia Agents; Benzazepines; Female; Germany; Heart; Heart Rate; Heart Transplantation; Humans; Hypertrophy, Left Ventricular; Ivabradine; Kaplan-Meier Estimate; Male; Metoprolol; Middle Aged; Retrospective Studies; Risk Factors; Tachycardia, Sinus; Time Factors; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling

2018
Effects of ivabradine on endothelial function, aortic properties and ventricular-arterial coupling in chronic systolic heart failure patients.
    Cardiovascular therapeutics, 2018, Volume: 36, Issue:3

    Topics: Aged; Aged, 80 and over; Aorta; Benzazepines; Cardiotonic Agents; Chronic Disease; Echocardiography; Endothelium, Vascular; Female; Heart Failure, Systolic; Heart Ventricles; Humans; Ivabradine; Male; Middle Aged; Vascular Stiffness; Ventricular Remodeling

2018
Heart rate reduction for 36 months with ivabradine reduces left ventricular mass in cardiac allograft recipients: a long-term follow-up study.
    Drug design, development and therapy, 2013, Volume: 7

    Topics: Adolescent; Adult; Aged; Benzazepines; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Heart Rate; Heart Transplantation; Heart Ventricles; Humans; Immunosuppressive Agents; Ivabradine; Male; Middle Aged; Mycophenolic Acid; Tachycardia, Sinus; Time Factors; Ventricular Remodeling; Young Adult

2013
Effect of ivabradine on left ventricular remodelling after reperfused myocardial infarction: A pilot study.
    Archives of cardiovascular diseases, 2014, Volume: 107, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Benzazepines; Drug Therapy, Combination; Feasibility Studies; Female; Heart Rate; Humans; Ivabradine; Magnetic Resonance Imaging; Male; Middle Aged; Myocardial Infarction; Myocardium; Percutaneous Coronary Intervention; Pilot Projects; Practice Guidelines as Topic; Time Factors; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling

2014
Effect of Chronic Heart Rate Reduction by I(f) Current Inhibitor Ivabradine on Left Ventricular Remodeling and Systolic Performance in Middle-Aged Rats With Postmyocardial Infarction Heart Failure.
    Journal of cardiovascular pharmacology and therapeutics, 2015, Volume: 20, Issue:3

    Topics: Aging; Animals; Benzazepines; Collagen; Coronary Vessels; Cyclic Nucleotide-Gated Cation Channels; Heart Failure; Heart Rate; Ivabradine; Male; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Systole; Ventricular Function, Left; Ventricular Remodeling

2015
Ivabradine improves left ventricular function during chronic hypertension in conscious pigs.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:1

    Topics: Animals; Benzazepines; Consciousness; Cyclic Nucleotide-Gated Cation Channels; Disease Models, Animal; Female; Heart Ventricles; Hypertension; Ivabradine; Swine; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling

2015
Heart Rate Reduction With Ivabradine Protects Against Left Ventricular Remodeling by Attenuating Infarct Expansion and Preserving Remote-Zone Contractile Function and Synchrony in a Mouse Model of Reperfused Myocardial Infarction.
    Journal of the American Heart Association, 2016, 04-22, Volume: 5, Issue:4

    Topics: Animals; Benzazepines; Cardiovascular Agents; Disease Models, Animal; Echocardiography; Heart Rate; Heart Ventricles; Ivabradine; Magnetic Resonance Imaging, Cine; Male; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Ventricular Function, Left; Ventricular Remodeling

2016
Pleiotropic action(s) of the bradycardic agent ivabradine: cardiovascular protection beyond heart rate reduction.
    British journal of pharmacology, 2008, Volume: 155, Issue:7

    Topics: Animals; Atherosclerosis; Benzazepines; Cardiotonic Agents; Disease Models, Animal; Heart Rate; Humans; Ivabradine; Myocardial Infarction; Myocardial Reperfusion Injury; Ventricular Remodeling

2008
Beneficial effects of delayed ivabradine treatment on cardiac anatomical and electrical remodeling in rat severe chronic heart failure.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Benzazepines; Collagen; Disease Models, Animal; Drug Administration Schedule; Echocardiography, Doppler; Electrocardiography, Ambulatory; Fibrosis; Heart Failure; Heart Rate; Ivabradine; Male; Myocardial Infarction; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Severity of Illness Index; Stroke Volume; Telemetry; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Pressure; Ventricular Remodeling

2009
Postmyocardial infarction remodeling and coronary reserve: effects of ivabradine and beta blockade therapy.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:1

    Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Atenolol; Benzazepines; Bradykinin; Cardiotonic Agents; Collagen; Coronary Circulation; Electrocardiography; Heart Rate; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Ivabradine; Male; Myocardial Infarction; Neovascularization, Physiologic; Organ Size; Perfusion; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Ventricular Remodeling

2009
Heart rate reduction with ivabradine prevents the global phenotype of left ventricular remodeling.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:1

    Topics: Action Potentials; Animals; Benzazepines; Electrocardiography; Energy Metabolism; Heart; Heart Rate; Ivabradine; Male; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; Ventricular Function, Left; Ventricular Remodeling

2011
Long-term treatment with ivabradine in post-myocardial infarcted rats counteracts f-channel overexpression.
    British journal of pharmacology, 2012, Volume: 165, Issue:5

    Topics: Animals; Benzazepines; Cyclic Nucleotide-Gated Cation Channels; Heart Atria; Heart Rate; Heart Ventricles; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channels; Ivabradine; Male; MicroRNAs; Myocardial Infarction; Myocytes, Cardiac; Potassium Channels; Rats; Rats, Wistar; Ventricular Remodeling

2012
Left ventricular remodelling in systolic heart failure using ivabradine. Slower is smaller is better?
    European heart journal, 2011, Volume: 32, Issue:20

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Female; Heart Failure; Humans; Ivabradine; Male; Ventricular Dysfunction, Left; Ventricular Remodeling

2011
Natural history of end-stage LV dysfunction: has it improved from the classic Franciosa and Cohn Graph?
    Cardiology clinics, 2011, Volume: 29, Issue:4

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Cardiac Resynchronization Therapy; Defibrillators, Implantable; Heart Failure; Heart-Assist Devices; Humans; Hydralazine; Ivabradine; Mineralocorticoid Receptor Antagonists; Nitrates; Renin-Angiotensin System; Risk Factors; Survival Analysis; Sympathetic Nervous System; Treatment Outcome; Ventricular Dysfunction, Left; Ventricular Remodeling

2011
Role of heart rate reduction in the prevention of experimental heart failure: comparison between If-channel blockade and β-receptor blockade.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:5

    Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin II; Animals; Apoptosis; Benzazepines; Cyclic Nucleotide-Gated Cation Channels; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Heart Failure; Heart Rate; Immunohistochemistry; In Situ Nick-End Labeling; Ivabradine; Male; Metoprolol; Mice; Mice, Inbred C57BL; Multivariate Analysis; Random Allocation; Sensitivity and Specificity; Statistics, Nonparametric; Tachycardia; Treatment Outcome; Ventricular Dysfunction, Left; Ventricular Remodeling

2012
Influence of ivabradine on reverse remodelling during mechanical unloading.
    Cardiovascular research, 2013, Feb-01, Volume: 97, Issue:2

    Topics: Animals; Atrophy; Benzazepines; Calcium; Calcium Channels, L-Type; Excitation Contraction Coupling; Fibrosis; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; Ivabradine; Metoprolol; Myocardium; Rats; Ventricular Remodeling

2013
[Effect of ivabradin on heart rate, left ventricular function a NT-proBNP concentration in patients with systolic chronic heart failure--case reports].
    Vnitrni lekarstvi, 2012, Volume: 58, Issue:10

    Topics: Adult; Aged; Benzazepines; Chronic Disease; Cyclic Nucleotide-Gated Cation Channels; Female; Heart Failure, Systolic; Heart Rate; Humans; Ivabradine; Male; Natriuretic Peptide, Brain; Peptide Fragments; Ventricular Function, Left; Ventricular Remodeling

2012
Heart rate reduction with ivabradine prevents thyroid hormone-induced cardiac remodeling in rat.
    Heart and vessels, 2013, Volume: 28, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Benzazepines; Calcium Signaling; Disease Models, Animal; Fibrosis; Heart Rate; Heart Ventricles; Hyperthyroidism; Ivabradine; Male; Myocardial Contraction; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Stroke Volume; Thyroxine; Ultrasonography; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling

2013
Long-term heart rate reduction induced by the selective I(f) current inhibitor ivabradine improves left ventricular function and intrinsic myocardial structure in congestive heart failure.
    Circulation, 2004, Apr-06, Volume: 109, Issue:13

    Topics: Animals; Benzazepines; Capillaries; Cardiac Output; Collagen; Drug Evaluation, Preclinical; Heart Failure; Heart Rate; Heart Ventricles; Ion Transport; Ivabradine; Male; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; Sinoatrial Node; Stroke Volume; Ventricular Function, Left; Ventricular Remodeling

2004
Effect of long-term heart rate reduction by If current inhibition on pressure overload-induced heart failure in rats.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 324, Issue:1

    Topics: Animals; Atrial Natriuretic Factor; Benzazepines; Heart Failure; Heart Rate; Hypertrophy, Left Ventricular; Ivabradine; Male; Rats; Rats, Wistar; RNA, Messenger; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Ventricular Pressure; Ventricular Remodeling

2008
Effect of metoprolol and ivabradine on left ventricular remodelling and Ca2+ handling in the post-infarction rat heart.
    Cardiovascular research, 2008, Jul-01, Volume: 79, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Benzazepines; Calcium; Disease Models, Animal; Heart Failure; Heart Rate; Hypertrophy, Left Ventricular; Ivabradine; Male; Metoprolol; Myocardial Infarction; Rats; Rats, Wistar; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sodium-Calcium Exchanger; Ventricular Remodeling

2008